DATE_ADDED_TO_CATALOG PUBMEDID FIRST_AUTHOR DATE JOURNAL LINK STUDY DISEASE_TRAIT INITIAL_SAMPLE_SIZE REPLICATION_SAMPLE_SIZE PLATFORM_[SNPS_PASSING_QC] ASSOCIATION_COUNT MAPPED_TRAIT MAPPED_TRAIT_URI STUDY_ACCESSION GENOTYPING_TECHNOLOGY study_N 2017-06-21 28358029 Afshari NA 2017-03-30 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28358029 Genome-wide association study identifies three novel loci in Fuchs endothelial corneal dystrophy. Fuchs's corneal dystrophy 1,404 European ancestry cases, 2,564 European ancestry controls 671 European ancestry cases, 778 European ancestry controls Illumina [8680745] (imputed) 6 Fuchs endothelial corneal dystrophy http://www.orpha.net/ORDO/Orphanet_98974 GCST004217 Genome-wide genotyping array 3968 2018-01-09 26545403 Bei JX 2016-01-01 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/26545403 A GWAS Meta-analysis and Replication Study Identifies a Novel Locus within CLPTM1L/TERT Associated with Nasopharyngeal Carcinoma in Individuals of Chinese Ancestry. Nasopharyngeal carcinoma 2,152 Chinese ancestry cases, 3,740 Chinese ancestry controls 4,716 Chinese ancestry cases, 5,379 Chinese ancestry controls Illumina [Sequenom custom array used in replication] (imputed) 8 nasopharyngeal neoplasm http://www.ebi.ac.uk/efo/EFO_0004252 GCST005113 Genome-wide genotyping array 5892 2018-01-17 29208002 Kim M 2017-12-06 Lipids Health Dis www.ncbi.nlm.nih.gov/pubmed/29208002 EPHA6 rs4857055 C > T polymorphism associates with hypertension through triglyceride and LDL particle size in the Korean population. Diastolic blood pressure 2146 East Asian ancestry individuals NA Affymetrix [394222] 6 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST005169 Genome-wide genotyping array 2146 2018-01-17 29208002 Kim M 2017-12-06 Lipids Health Dis www.ncbi.nlm.nih.gov/pubmed/29208002 EPHA6 rs4857055 C > T polymorphism associates with hypertension through triglyceride and LDL particle size in the Korean population. Systolic blood pressure 2146 East Asian ancestry individuals NA Affymetrix [394222] 6 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST005168 Genome-wide genotyping array 2146 2018-01-15 29228715 Hofer P 2017-10-09 Oncotarget www.ncbi.nlm.nih.gov/pubmed/29228715 Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas. Colorectal cancer 978 Austrian ancestry colorectal cancer cases, 636 Austrian ancestry advanced colorectal adenoma cases, , 855 Austrian ancestry controls NA Affymetrix [492217] (imputed) 6 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST005148 Genome-wide genotyping array 2469 2018-01-15 29228715 Hofer P 2017-10-09 Oncotarget www.ncbi.nlm.nih.gov/pubmed/29228715 Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas. Colorectal cancer 978 Austrian ancestry cases, 4,294 European ancestry controls NA Affymetrix [492217] (imputed) 42 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST005149 Genome-wide genotyping array 5272 2018-01-15 29228715 Hofer P 2017-10-09 Oncotarget www.ncbi.nlm.nih.gov/pubmed/29228715 Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas. Colorectal cancer 978 Austrian ancestry colorectal cancer cases, 636 Austrian ancestry advanced colorectal adenoma cases, 4,294 European ancestry controls NA Affymetrix [492217] (imputed) 42 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST005150 Genome-wide genotyping array 5908 2018-01-15 29228715 Hofer P 2017-10-09 Oncotarget www.ncbi.nlm.nih.gov/pubmed/29228715 Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas. Colorectal adenoma (advanced) 636 Austrian ancestry cases, 4,294 European ancestry controls NA Affymetrix [492217] (imputed) 21 colorectal adenoma http://www.ebi.ac.uk/efo/EFO_0005406 GCST005151 Genome-wide genotyping array 4930 2018-01-15 29228715 Hofer P 2017-10-09 Oncotarget www.ncbi.nlm.nih.gov/pubmed/29228715 Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas. Colorectal cancer 978 Austrian ancestry cases, 855 Austrian ancestry controls NA Affymetrix [492217] (imputed) 13 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST005152 Genome-wide genotyping array 1833 2018-01-15 29228715 Hofer P 2017-10-09 Oncotarget www.ncbi.nlm.nih.gov/pubmed/29228715 Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas. Colorectal adenoma (advanced) 636 Austrian ancestry cases, 855 Austrian ancestry controls NA Affymetrix [492217] (imputed) 9 colorectal adenoma http://www.ebi.ac.uk/efo/EFO_0005406 GCST005153 Genome-wide genotyping array 1491 2018-01-15 29228715 Hofer P 2017-10-09 Oncotarget www.ncbi.nlm.nih.gov/pubmed/29228715 Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas. Colonoscopy-negative controls vs population controls 855 Austrian ancestry colonoscopy-negative controls, 3,439 European ancestry controls NA Affymetrix [492217] (imputed) 131 colorectal health http://www.ebi.ac.uk/efo/EFO_0008460 GCST005147 Genome-wide genotyping array 4294 2017-12-05 29083406 Ferreira MA 2017-10-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29083406 Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology. Allergic disease (asthma, hay fever or eczema) 180,129 European ancestry cases, 180,709 European ancestry controls NA Affymetrix, Illumina [8307659] (imputed) 136 allergy http://www.ebi.ac.uk/efo/EFO_0003785 GCST005038 Genome-wide genotyping array 360838 2017-09-12 28701861 Randall CL 2017-06-15 Pain Res Manag www.ncbi.nlm.nih.gov/pubmed/28701861 A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain. Fear of severe pain Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals NA Illumina [8591557] (imputed) 8 fear of severe pain measurement http://www.ebi.ac.uk/efo/EFO_0008338 GCST004709 Genome-wide genotyping array 1583 2017-09-12 28701861 Randall CL 2017-06-15 Pain Res Manag www.ncbi.nlm.nih.gov/pubmed/28701861 A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain. Fear of minor pain Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals NA Illumina [8591557] (imputed) 19 fear of minor pain measurement http://www.ebi.ac.uk/efo/EFO_0008340 GCST004708 Genome-wide genotyping array 1583 2017-09-12 28701861 Randall CL 2017-06-15 Pain Res Manag www.ncbi.nlm.nih.gov/pubmed/28701861 A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain. Fear of medical pain (dental) Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals NA Illumina [8591557] (imputed) 6 fear of medical pain measurement http://www.ebi.ac.uk/efo/EFO_0008339 GCST004707 Genome-wide genotyping array 1583 2017-09-12 28701861 Randall CL 2017-06-15 Pain Res Manag www.ncbi.nlm.nih.gov/pubmed/28701861 A Preliminary Genome-Wide Association Study of Pain-Related Fear: Implications for Orofacial Pain. Fear of pain Up to 1,367 European ancestry individuals, up to 159 African American individuals, up to 13 Hispanic individuals, up to 23 Asian, Native American and other ancestry individuals, up to 21 individuals NA Illumina [8591557] (imputed) 4 fear of pain measurement http://www.ebi.ac.uk/efo/EFO_0008330 GCST004706 Genome-wide genotyping array 1583 2017-11-20 28927378 Qian DC 2017-09-19 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/28927378 Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction. Caudate activity during disappointment 106 individuals NA Illumina [at least 621854] (imputed) 0 caudate nucleus measurement, response to disappointment, functional brain measurement http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0008397, http://www.ebi.ac.uk/efo/EFO_0007849 GCST004969 Genome-wide genotyping array 106 2017-11-20 28927378 Qian DC 2017-09-19 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/28927378 Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction. Caudate activity during reward 106 individuals NA Illumina [at least 621854] (imputed) 31 caudate nucleus measurement, functional brain measurement, response to reward http://www.ebi.ac.uk/efo/EFO_0008387, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008396 GCST004970 Genome-wide genotyping array 106 2017-11-20 28927378 Qian DC 2017-09-19 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/28927378 Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction. Putamen activity during reward 106 individuals NA Illumina [at least 621854] (imputed) 0 functional brain measurement, putamen measurement, response to reward http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008389, http://www.ebi.ac.uk/efo/EFO_0008396 GCST004971 Genome-wide genotyping array 106 2017-11-20 28927378 Qian DC 2017-09-19 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/28927378 Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction. Putamen actvity during disappointment 106 individuals NA Illumina [at least 621854] (imputed) 0 response to disappointment, functional brain measurement, putamen measurement http://www.ebi.ac.uk/efo/EFO_0008397, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0008389 GCST004972 Genome-wide genotyping array 106 2017-08-01 28512139 Mack S 2017-05-16 J Lipid Res www.ncbi.nlm.nih.gov/pubmed/28512139 A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms. Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms 13,781 European ancestry individuals NA Affymetrix, Illumina [at least 7600000] (imputed) 28 lipoprotein A measurement, apolipoprotein A 1 measurement http://www.ebi.ac.uk/efo/EFO_0006925, http://www.ebi.ac.uk/efo/EFO_0004614 GCST004399 Genome-wide genotyping array 13781 2017-08-01 28512139 Mack S 2017-05-16 J Lipid Res www.ncbi.nlm.nih.gov/pubmed/28512139 A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms. Lipoprotein (a) levels 13,781 European ancestry individuals NA Affymetrix, Illumina [at least 7600000] (imputed) 44 lipoprotein A measurement http://www.ebi.ac.uk/efo/EFO_0006925 GCST004398 Genome-wide genotyping array 13781 2018-03-12 29381699 Ravenhall M 2018-01-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29381699 Novel genetic polymorphisms associated with severe malaria and under selective pressure in North-eastern Tanzania. Severe malaria (adjusted for sickle cell variant rs334) 449 Tanzanian ancestry cases, 465 Tanzanian ancestry controls NA Illumina [15200000] (imputed) 14 malaria http://www.ebi.ac.uk/efo/EFO_0001068 GCST005357 Genome-wide genotyping array 914 2018-03-12 29381699 Ravenhall M 2018-01-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29381699 Novel genetic polymorphisms associated with severe malaria and under selective pressure in North-eastern Tanzania. Severe malaria 449 Tanzanian ancestry cases, 465 Tanzanian ancestry controls NA Illumina [15200000] (imputed) 15 malaria http://www.ebi.ac.uk/efo/EFO_0001068 GCST005356 Genome-wide genotyping array 914 2018-03-05 29367611 Gao B 2018-01-24 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29367611 Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer. Paclitaxel disposition in epithelial ovarian cancer 66 European ancestry cases, 14 Asian ancestry cases NA Illumina [610255] 31 response to paclitaxel http://purl.obolibrary.org/obo/GO_1901555 GCST005352 Genome-wide genotyping array 80 2018-03-05 29367611 Gao B 2018-01-24 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29367611 Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer. Carboplatin disposition in epthelial ovarian cancer 42 European ancestry cases, 14 Asian ancestry cases NA Illumina [610255] 18 response to carboplatin http://purl.obolibrary.org/obo/GO_0097328 GCST005351 Genome-wide genotyping array 56 2017-10-20 28935272 Moore KN 2017-09-18 Gynecol Oncol www.ncbi.nlm.nih.gov/pubmed/28935272 Genome-wide association study evaluating single-nucleotide polymorphisms and outcomes in patients with advanced stage serous ovarian or primary peritoneal cancer: An NRG Oncology/Gynecologic Oncology Group study. Progression free survival in serous epithelial ovarian cancer treated with carboplatin and paclitaxel 147 European ancestry women NA Illumina [636555] 4 progression free survival, ovarian carcinoma, response to cisplatin, response to paclitaxel http://www.ebi.ac.uk/efo/EFO_0004920, http://www.ebi.ac.uk/efo/EFO_0001075, http://purl.obolibrary.org/obo/GO_0072718, http://purl.obolibrary.org/obo/GO_1901555 GCST004897 Genome-wide genotyping array 147 2017-10-20 28935272 Moore KN 2017-09-18 Gynecol Oncol www.ncbi.nlm.nih.gov/pubmed/28935272 Genome-wide association study evaluating single-nucleotide polymorphisms and outcomes in patients with advanced stage serous ovarian or primary peritoneal cancer: An NRG Oncology/Gynecologic Oncology Group study. Overall survival in serous epithelial ovarian cancer treated with paclitaxel and cisplatin 289 European ancestry women NA Illumina [636555] 10 overall survival, ovarian carcinoma, response to cisplatin, response to paclitaxel http://www.ebi.ac.uk/efo/EFO_0000638, http://www.ebi.ac.uk/efo/EFO_0001075, http://purl.obolibrary.org/obo/GO_0072718, http://purl.obolibrary.org/obo/GO_1901555 GCST004896 Genome-wide genotyping array 289 2018-01-30 29196614 Sud A 2017-12-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29196614 Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility. Nodular sclerosis Hodgkin lymphoma 1,278 European ancestry cases, 14,325 European ancestry controls 1,586 cases, 3,069 controls Illumina [> 10000000] (imputed) 9 nodular sclerosis Hodgkin lymphoma http://www.ebi.ac.uk/efo/EFO_0004708 GCST005211 Genome-wide genotyping array 15603 2018-01-30 29196614 Sud A 2017-12-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29196614 Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility. Mixed cellularity Hodgkin lymphoma 828 European ancestry cases, 14,315 European ancestry controls 135 cases, 3,069 controls Illumina [> 10000000] (imputed) 3 Hodgkins lymphoma, mixed cellularity http://www.ebi.ac.uk/efo/EFO_1002031 GCST005210 Genome-wide genotyping array 15143 2018-01-30 29196614 Sud A 2017-12-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29196614 Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility. Hodgkin's lymphoma 3,077 European ancestry cases, 13,680 European ancestry controls 2,237 cases, 3,069 controls Illumina [> 10000000] (imputed) 6 Hodgkins lymphoma http://www.ebi.ac.uk/efo/EFO_0000183 GCST005209 Genome-wide genotyping array 16757 2017-09-15 28608620 Coleman JRI 2017-06-13 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/28608620 Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders. Facial emotion recognition 4,097 European ancestry individuals NA Illumina [2487351] (imputed) 3 facial emotion recognition measurement http://www.ebi.ac.uk/efo/EFO_0008329 GCST004727 Genome-wide genotyping array 4097 2017-09-15 28608620 Coleman JRI 2017-06-13 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/28608620 Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders. Facial emotion recognition (happy faces) 4,097 European ancestry individuals NA Illumina [2487351] (imputed) 1 facial emotion recognition measurement http://www.ebi.ac.uk/efo/EFO_0008329 GCST004729 Genome-wide genotyping array 4097 2017-09-15 28608620 Coleman JRI 2017-06-13 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/28608620 Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders. Facial emotion recognition (sad faces) 4,097 European ancestry individuals NA Illumina [2487351] (imputed) 4 facial emotion recognition measurement http://www.ebi.ac.uk/efo/EFO_0008329 GCST004730 Genome-wide genotyping array 4097 2017-09-15 28608620 Coleman JRI 2017-06-13 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/28608620 Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders. Facial emotion recognition (angry faces) 4,097 European ancestry individuals NA Illumina [2487351] (imputed) 4 facial emotion recognition measurement http://www.ebi.ac.uk/efo/EFO_0008329 GCST004728 Genome-wide genotyping array 4097 2017-09-15 28608620 Coleman JRI 2017-06-13 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/28608620 Genome-wide association study of facial emotion recognition in children and association with polygenic risk for mental health disorders. Facial emotion recognition (fearful faces) 4,097 European ancestry individuals NA Illumina [2487351] (imputed) 2 facial emotion recognition measurement http://www.ebi.ac.uk/efo/EFO_0008329 GCST004731 Genome-wide genotyping array 4097 2018-03-29 29358691 Bonas-Guarch S 2018-01-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29358691 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes. Type 2 diabetes 19,693 European ancestry cases, 107,308 European ancestry controls, 6,952 East Asian ancestry cases, 11,865 East Asian ancestry controls, 5,561 South Asian ancestry cases, 14,458 South Asian ancestry controls, 1,804 Mexican ancestry cases, 779 Mexican ancestry controls NA Affymetrix, Illumina [1918233] (imputed) 24 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST005414 Genome-wide genotyping array 168420 2018-03-29 29358691 Bonas-Guarch S 2018-01-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29358691 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes. Type 2 diabetes up to 12,931 European ancestry cases, up to 57,196 European ancestry controls NA Affymetrix, Illumina [~ 13000000] (imputed) 20 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST005413 Genome-wide genotyping array 70127 2018-07-16 29358691 Bonas-Guarch S 2018-01-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29358691 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes. Type 2 diabetes 7,522 European ancestry cases, 50,446 European ancestry controls 35,789 African-American, East Asian, South Asian, European or Hispanic cases, 56,738 African-American, East Asian, South Asian, European or Hispanic controls Affymetrix, Illumina [1918233] (imputed) 1 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST005899 Exome genotyping array [Exome array] 57968 2018-07-16 29358691 Bonas-Guarch S 2018-01-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29358691 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes. Type 2 diabetes 5,277 European ancestry cases, 15,702 European ancestry controls 9,253 European ancestry cases and controls, 3,490 Hispanic case and controls, 174,532 cases and controls Affymetrix, Illumina [~ 1000000] (imputed) 1 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST005898 Genome-wide genotyping array 20979 2017-12-01 28924203 Ren HY 2017-09-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28924203 The common variants implicated in microstructural abnormality of first episode and drug-naïve patients with schizophrenia. White matter microstructure in first episode schizophrenia (right posterior cingulate cortex) 93 Han Chinese cases, 134 Han Chinese controls NA Illumina [6055918] (imputed) 1 white matter microstructure measurement, cingulate cortex measurement http://www.ebi.ac.uk/efo/EFO_0005674, http://www.ebi.ac.uk/efo/EFO_0007738 GCST004992 Genome-wide genotyping array 227 2017-12-01 28924203 Ren HY 2017-09-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28924203 The common variants implicated in microstructural abnormality of first episode and drug-naïve patients with schizophrenia. Total mean fractional anisotropy measurement in first episode schizophrenia 93 Han Chinese cases, 134 Han Chinese controls NA Illumina [6055918] (imputed) 1 mean fractional anisotropy measurement, white matter microstructure measurement http://www.ebi.ac.uk/efo/EFO_0008399, http://www.ebi.ac.uk/efo/EFO_0005674 GCST004996 Genome-wide genotyping array 227 2017-12-01 28924203 Ren HY 2017-09-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28924203 The common variants implicated in microstructural abnormality of first episode and drug-naïve patients with schizophrenia. White matter microstructure in first episode schizophrenia (left posterior cingulate cortex) 93 Han Chinese cases, 134 Han Chinese controls NA Illumina [6055918] (imputed) 1 white matter microstructure measurement, cingulate cortex measurement http://www.ebi.ac.uk/efo/EFO_0005674, http://www.ebi.ac.uk/efo/EFO_0007738 GCST004995 Genome-wide genotyping array 227 2017-12-01 28924203 Ren HY 2017-09-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28924203 The common variants implicated in microstructural abnormality of first episode and drug-naïve patients with schizophrenia. White matter microstructure in first episode schizophrenia (left inferior parietal cortex) 93 Han Chinese cases, 134 Han Chinese controls NA Illumina [6055918] (imputed) 1 parietal cortex measurement, white matter microstructure measurement http://www.ebi.ac.uk/efo/EFO_0008420, http://www.ebi.ac.uk/efo/EFO_0005674 GCST004991 Genome-wide genotyping array 227 2017-12-01 28924203 Ren HY 2017-09-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28924203 The common variants implicated in microstructural abnormality of first episode and drug-naïve patients with schizophrenia. Abnormal white matter microstructure in first episode schizophrenia (multivariate analysis) 93 Han Chinese cases, 134 Han Chinese controls NA Illumina [6055918] (imputed) 1 parietal cortex measurement, white matter microstructure measurement, cingulate cortex measurement http://www.ebi.ac.uk/efo/EFO_0008420, http://www.ebi.ac.uk/efo/EFO_0005674, http://www.ebi.ac.uk/efo/EFO_0007738 GCST004997 Genome-wide genotyping array 227 2017-12-01 28924203 Ren HY 2017-09-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28924203 The common variants implicated in microstructural abnormality of first episode and drug-naïve patients with schizophrenia. White matter microstructure in first episode schizophrenia (left anterior cingulate cortex) 93 Han Chinese cases, 134 Han Chinese controls NA Illumina [6055918] (imputed) 1 white matter microstructure measurement, cingulate cortex measurement http://www.ebi.ac.uk/efo/EFO_0005674, http://www.ebi.ac.uk/efo/EFO_0007738 GCST004994 Genome-wide genotyping array 227 2017-12-01 28924203 Ren HY 2017-09-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28924203 The common variants implicated in microstructural abnormality of first episode and drug-naïve patients with schizophrenia. White matter microstructure in first episode schizophrenia (right anterior cingulate cortex) 93 Han Chinese cases, 134 Han Chinese controls NA Illumina [6055918] (imputed) 1 white matter microstructure measurement, cingulate cortex measurement http://www.ebi.ac.uk/efo/EFO_0005674, http://www.ebi.ac.uk/efo/EFO_0007738 GCST004993 Genome-wide genotyping array 227 2017-07-06 28452372 Gorski M 2017-04-28 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28452372 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. Glomerular filtration rate (cystatin C) 24,063 European ancestry individuals NA Affymetrix, Illumina [up to 10971307] (imputed) 3 glomerular filtration rate, cystatin C measurement http://www.ebi.ac.uk/efo/EFO_0005208, http://www.ebi.ac.uk/efo/EFO_0004617 GCST004293 Genome-wide genotyping array 24063 2017-07-06 28452372 Gorski M 2017-04-28 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28452372 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. Glomerular filtration rate (creatinine) 110,517 European ancestry individuals NA Affymetrix, Illumina [up to 10971307] (imputed) 57 creatinine measurement, glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208 GCST004292 Genome-wide genotyping array 110517 2018-05-14 22961000 Liu JZ 2012-10-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22961000 Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis. Primary biliary cirrhosis 2,861 British and Irish ancestry cases, 8,514 British and Irish ancestry controls NA Illumina [237619] (imputed) 47 primary biliary cirrhosis http://www.ebi.ac.uk/efo/EFO_1001486 GCST005581 Targeted genotyping array [ImmunoChip] 11375 2017-06-27 28183528 Jun GR 2017-02-06 Alzheimers Dement www.ncbi.nlm.nih.gov/pubmed/28183528 Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimer's disease 13,100 European ancestry cases, 13,220 European ancestry controls, 1,472 African American cases, 3,511 African American controls, 951 Japanese ancestry cases, 894 Japanese ancestry controls, 51 Israeli-Arab ancestry cases, 64 Israeli-Arab ancestry controls 5,813 European ancestry cases, 20,474 European ancestry controls NR [NR] 11 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST004246 Genome-wide genotyping array 33263 2017-06-27 28183528 Jun GR 2017-02-06 Alzheimers Dement www.ncbi.nlm.nih.gov/pubmed/28183528 Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimer's disease (APOE e4 interaction) 8,271 European ancestry APOE e4+ cases, 3,480 European ancestry APOE e4+ controls, 4,829 European ancestry APOE e4- cases, 9,740 European ancestry APOE e4- controls, 865 African American APOE e4+ cases, 1,241 African American APOE e4+ control, 607 African American APOE 4e- cases, 2,270 African American APOE 4e- controls, 535 Japanese ancestry APOE 4e+ cases, 151 Japanese ancestry APOE 4+ controls, 416 Japanese ancestry APOE 4- cases, 743 Japanese ancestry APOE 4- controls, 51 Arab-Israeli ancestry APOE e4- cases, 64 Arab-Israeli ancestry e4- controls 3,062 European ancestry APOE e4+ cases, 8,977 European ancestry APOE e4+ controls, 2,751 European ancestry APOE e4- cases, 11,497 European ancestry APOE e4- controls NR [NR] 1 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST004247 Genome-wide genotyping array 33319 2017-06-27 28183528 Jun GR 2017-02-06 Alzheimers Dement www.ncbi.nlm.nih.gov/pubmed/28183528 Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimer's disease in APOE e4+ carriers 8,271 European ancestry cases, 3,480 European ancestry controls, 865 African American cases, 1,241 African American control, 535 Japanese ancestry cases, 151 Japanese ancestry controls 3,062 European ancestry cases, 8,977 European ancestry controls NR [NR] 0 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST004248 Genome-wide genotyping array 14543 2017-06-27 28183528 Jun GR 2017-02-06 Alzheimers Dement www.ncbi.nlm.nih.gov/pubmed/28183528 Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimer's disease in APOE e4- carriers 4,829 European ancestry cases, 9,740 European ancestry controls, 607 African American cases, 2,270 African American controls, 416 Japanese ancestry cases, 743 Japanese ancestry controls, 51 Israeli-Arab ancestry cases, 64 Israeli-Arab ancestry controls 2,751 European ancestry cases, 11,497 European ancestry controls NR [NR] 3 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST004249 Genome-wide genotyping array 18720 2017-06-23 28355232 Ward-Caviness CK 2017-03-29 PLoS One www.ncbi.nlm.nih.gov/pubmed/28355232 A genome-wide trans-ethnic interaction study links the PIGR-FCAMR locus to coronary atherosclerosis via interactions between genetic variants and residential exposure to traffic. Coronary atherosclerosis (increased number of diseased vessels) (traffic exposure interaction) 1,562 European ancestry individuals, 538 African American individuals NA Illumina [at least 756588] 15 coronary atherosclerosis measurement, traffic air pollution measurement http://www.ebi.ac.uk/efo/EFO_0007938, http://www.ebi.ac.uk/efo/EFO_0007908 GCST004224 Genome-wide genotyping array 2100 2017-07-07 28440896 Yin X 2017-04-25 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/28440896 Genome-wide meta-analysis identifies a novel susceptibility signal at CACNA2D3 for nicotine dependence. Nicotine dependence 7,297 European ancestry cases, 5,577 European ancestry controls, 918 European ancestry whole genome sequenced cases, 921 European ancestry whole genome sequenced controls, African American cases, 1,500 African American controls NA Illumina [at least 3251541] (imputed) 14 nicotine dependence http://www.ebi.ac.uk/efo/EFO_0003768 GCST004294 Genome-wide genotyping array 16213 2017-12-19 29058716 Milne RL 2017-10-23 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29058716 Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer. Breast cancer (estrogen-receptor negative) 14,135 European ancestry cases, 58,126 European ancestry controls 7,333 European ancestry cases, 42,468 European ancestry controls Illumina [~ 11500000] (imputed) 46 estrogen-receptor negative breast cancer http://www.ebi.ac.uk/efo/EFO_1000650 GCST005076 Genome-wide genotyping array 72261 2017-12-19 29058716 Milne RL 2017-10-23 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29058716 Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer. Breast cancer 14,135 European ancestry ER- cases, 58,126 European ancestry controls, 7,784 European ancestry BRCA1 carrrier cases, 7,782 European ancestry BRCA1 carrrier controls 7,333 European ancestry ER- cases, 42,468 European ancestry controls, 1,630 European ancestry BRCA1 carrrier cases, 1,712 European ancestry BRCA1 carrrier controls Illumina [~ 11500000] (imputed) 10 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST005077 Genome-wide genotyping array 87829 2017-12-19 29058716 Milne RL 2017-10-23 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29058716 Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer. Breast Cancer in BRCA1 mutation carriers 7,784 European ancestry carrier cases, 7,782 European ancestry carrier controls 1,630 European ancestry carrier cases, 1,712 European ancestry carrier controls Illumina [~ 11500000] (imputed) 10 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST005075 Genome-wide genotyping array 15566 2017-12-01 29071344 Zhou H 2017-10-25 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/29071344 Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression. Major depression and alcohol dependence 3,041 African American individuals, 1,618 European ancestry individuals 1,612 African American individuals, 1,551 European ancestry individuals Illumina [at least 5086170] (imputed) 47 unipolar depression, alcohol dependence http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0003829 GCST005022 Genome-wide genotyping array 4659 2018-08-16 27271309 Li C 2016-08-01 Hypertension www.ncbi.nlm.nih.gov/pubmed/27271309 Genome-Wide Gene-Sodium Interaction Analyses on Blood Pressure: The Genetic Epidemiology Network of Salt-Sensitivity Study. Diastolic blood pressure x sodium interaction (1df test) 1,876 Han Chinese ancestry individuals 775 Chinese ancestry individuals Affymetrix [2216774] (imputed) 1 sodium measurement, diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0009282, http://www.ebi.ac.uk/efo/EFO_0006336 GCST006112 Genome-wide genotyping array 1876 2018-08-16 27271309 Li C 2016-08-01 Hypertension www.ncbi.nlm.nih.gov/pubmed/27271309 Genome-Wide Gene-Sodium Interaction Analyses on Blood Pressure: The Genetic Epidemiology Network of Salt-Sensitivity Study. Systolic blood pressure x sodium interaction (2df test) 1,876 Han Chinese ancestry individuals 775 Chinese ancestry individuals Affymetrix [2216774] (imputed) 2 sodium measurement, systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0009282, http://www.ebi.ac.uk/efo/EFO_0006335 GCST006113 Genome-wide genotyping array 1876 2018-08-16 27271309 Li C 2016-08-01 Hypertension www.ncbi.nlm.nih.gov/pubmed/27271309 Genome-Wide Gene-Sodium Interaction Analyses on Blood Pressure: The Genetic Epidemiology Network of Salt-Sensitivity Study. Diastolic blood pressure x sodium interaction (2df test) 1,876 Han Chinese ancestry individuals 775 Chinese ancestry individuals Affymetrix [2216774] (imputed) 2 sodium measurement, diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0009282, http://www.ebi.ac.uk/efo/EFO_0006336 GCST006111 Genome-wide genotyping array 1876 2018-08-16 27271309 Li C 2016-08-01 Hypertension www.ncbi.nlm.nih.gov/pubmed/27271309 Genome-Wide Gene-Sodium Interaction Analyses on Blood Pressure: The Genetic Epidemiology Network of Salt-Sensitivity Study. Mean arterial pressure x sodium interaction (2df test) 1,876 Han Chinese ancestry individuals 775 Chinese ancestry individuals Affymetrix [2216774] (imputed) 1 sodium measurement, mean arterial pressure http://www.ebi.ac.uk/efo/EFO_0009282, http://www.ebi.ac.uk/efo/EFO_0006340 GCST006114 Genome-wide genotyping array 1876 2018-08-16 27271309 Li C 2016-08-01 Hypertension www.ncbi.nlm.nih.gov/pubmed/27271309 Genome-Wide Gene-Sodium Interaction Analyses on Blood Pressure: The Genetic Epidemiology Network of Salt-Sensitivity Study. Systolic blood pressure x sodium interaction (1df test) 1,876 Han Chinese ancestry individuals 775 Chinese ancestry individuals Affymetrix [2216774] (imputed) 0 sodium measurement, systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0009282, http://www.ebi.ac.uk/efo/EFO_0006335 GCST006115 Genome-wide genotyping array 1876 2018-08-16 27271309 Li C 2016-08-01 Hypertension www.ncbi.nlm.nih.gov/pubmed/27271309 Genome-Wide Gene-Sodium Interaction Analyses on Blood Pressure: The Genetic Epidemiology Network of Salt-Sensitivity Study. Mean arterial pressure x sodium interaction (1df test) 1,876 Han Chinese ancestry individuals 775 Chinese ancestry individuals Affymetrix [2216774] (imputed) 0 sodium measurement, mean arterial pressure http://www.ebi.ac.uk/efo/EFO_0009282, http://www.ebi.ac.uk/efo/EFO_0006340 GCST006116 Genome-wide genotyping array 1876 2018-08-16 27271309 Li C 2016-08-01 Hypertension www.ncbi.nlm.nih.gov/pubmed/27271309 Genome-Wide Gene-Sodium Interaction Analyses on Blood Pressure: The Genetic Epidemiology Network of Salt-Sensitivity Study. Pulse pressure x sodium interaction (1df test) 1,876 Han Chinese ancestry individuals 775 Chinese ancestry individuals Affymetrix [2216774] (imputed) 0 pulse pressure measurement, sodium measurement http://www.ebi.ac.uk/efo/EFO_0005763, http://www.ebi.ac.uk/efo/EFO_0009282 GCST006117 Genome-wide genotyping array 1876 2018-08-16 27271309 Li C 2016-08-01 Hypertension www.ncbi.nlm.nih.gov/pubmed/27271309 Genome-Wide Gene-Sodium Interaction Analyses on Blood Pressure: The Genetic Epidemiology Network of Salt-Sensitivity Study. Pulse pressure x sodium interaction (2df test) 1,876 Han Chinese ancestry individuals 775 Chinese ancestry individuals Affymetrix [2216774] (imputed) 0 pulse pressure measurement, sodium measurement http://www.ebi.ac.uk/efo/EFO_0005763, http://www.ebi.ac.uk/efo/EFO_0009282 GCST006118 Genome-wide genotyping array 1876 2017-11-27 29058489 Ogata S 2017-10-23 Clin Exp Hypertens www.ncbi.nlm.nih.gov/pubmed/29058489 Genome-wide association study for white coat effect in Japanese middle-aged to elderly people: The HOMED-BP study. White coat effect (clinic systolic blood pressure minus home systolic blood pressure) 295 Japanese ancestry individuals 236 Japanese ancestry individuals Affymetrix [6901629] (imputed) 0 response to stress, systolic blood pressure change measurement http://purl.obolibrary.org/obo/GO_0006950, http://www.ebi.ac.uk/efo/EFO_0006944 GCST004984 Genome-wide genotyping array 295 2017-11-27 29058489 Ogata S 2017-10-23 Clin Exp Hypertens www.ncbi.nlm.nih.gov/pubmed/29058489 Genome-wide association study for white coat effect in Japanese middle-aged to elderly people: The HOMED-BP study. White coat effect (clinic diastolic blood pressure minus home diastolic blood pressure) 295 Japanese ancestry individuals 236 Japanese ancestry individuals Affymetrix [6901629] (imputed) 0 diastolic blood pressure change measurement, response to stress http://www.ebi.ac.uk/efo/EFO_0006945, http://purl.obolibrary.org/obo/GO_0006950 GCST004985 Genome-wide genotyping array 295 2017-11-30 29058377 Sanchez-Roige S 2017-10-23 Addict Biol www.ncbi.nlm.nih.gov/pubmed/29058377 Genome-wide association study of alcohol use disorder identification test (AUDIT) scores in 20 328 research participants of European ancestry. Alcohol consumption over the past year 20,328 European ancestry individuals NA Illumina [13280794] (imputed) 5 alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0007878 GCST004990 Genome-wide genotyping array 20328 2018-01-17 29093273 Almgren P 2017-11-02 JCI Insight www.ncbi.nlm.nih.gov/pubmed/29093273 Genetic determinants of circulating GIP and GLP-1 concentrations. Insulin levels in response to oral glucose tolerance test (fasting) 3,344 Swedish ancestry individuals 4,905 Finnish ancestry individuals Illumina [at least 81396] 1 insulin measurement, glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0004467, http://www.ebi.ac.uk/efo/EFO_0004307 GCST005159 Genome-wide genotyping array 3344 2018-01-17 29093273 Almgren P 2017-11-02 JCI Insight www.ncbi.nlm.nih.gov/pubmed/29093273 Genetic determinants of circulating GIP and GLP-1 concentrations. Glucagon levels in response to oral glucose tolerance test (fasting) 3,344 Swedish ancestry individuals 4,905 Finnish ancestry individuals Illumina [at least 81396] 4 glucagon measurement, glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0008463, http://www.ebi.ac.uk/efo/EFO_0004307 GCST005162 Genome-wide genotyping array 3344 2018-01-17 29093273 Almgren P 2017-11-02 JCI Insight www.ncbi.nlm.nih.gov/pubmed/29093273 Genetic determinants of circulating GIP and GLP-1 concentrations. GIP levels in response to oral glucose tolerance test (fasting) 3,344 Swedish ancestry individuals 4,905 Finnish ancestry individuals Illumina [at least 81396] 2 glucose-dependent insulinotropic peptide measurement, glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0008464, http://www.ebi.ac.uk/efo/EFO_0004307 GCST005167 Genome-wide genotyping array 3344 2018-01-17 29093273 Almgren P 2017-11-02 JCI Insight www.ncbi.nlm.nih.gov/pubmed/29093273 Genetic determinants of circulating GIP and GLP-1 concentrations. GLP-1 levels in response to oral glucose tolerance test (fasting) 3,344 Swedish ancestry individuals 4,905 Finnish ancestry individuals Illumina [at least 81396] 4 glucagon-like peptide-1 measurement, glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0008465, http://www.ebi.ac.uk/efo/EFO_0004307 GCST005164 Genome-wide genotyping array 3344 2018-01-17 29093273 Almgren P 2017-11-02 JCI Insight www.ncbi.nlm.nih.gov/pubmed/29093273 Genetic determinants of circulating GIP and GLP-1 concentrations. Insulin levels in response to oral glucose tolerance test (30 minutes) 3,344 Swedish ancestry individuals 4,905 Finnish ancestry individuals Illumina [at least 81396] 3 insulin measurement, glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0004467, http://www.ebi.ac.uk/efo/EFO_0004307 GCST005160 Genome-wide genotyping array 3344 2018-01-17 29093273 Almgren P 2017-11-02 JCI Insight www.ncbi.nlm.nih.gov/pubmed/29093273 Genetic determinants of circulating GIP and GLP-1 concentrations. Insulin levels in response to oral glucose tolerance test (120 minutes) 3,344 Swedish ancestry individuals 4,905 Finnish ancestry individuals Illumina [at least 81396] 1 insulin measurement, glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0004467, http://www.ebi.ac.uk/efo/EFO_0004307 GCST005161 Genome-wide genotyping array 3344 2018-01-17 29093273 Almgren P 2017-11-02 JCI Insight www.ncbi.nlm.nih.gov/pubmed/29093273 Genetic determinants of circulating GIP and GLP-1 concentrations. GLP-1 levels in response to oral glucose tolerance test (120 minutes) 3,344 Swedish ancestry individuals 4,905 Finnish ancestry individuals Illumina [at least 81396] 1 glucagon-like peptide-1 measurement, glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0008465, http://www.ebi.ac.uk/efo/EFO_0004307 GCST005165 Genome-wide genotyping array 3344 2018-01-17 29093273 Almgren P 2017-11-02 JCI Insight www.ncbi.nlm.nih.gov/pubmed/29093273 Genetic determinants of circulating GIP and GLP-1 concentrations. GIP levels in response to oral glucose tolerance test (120 minutes) 3,344 Swedish ancestry individuals 4,905 Finnish ancestry individuals Illumina [at least 81396] 12 glucose-dependent insulinotropic peptide measurement, glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0008464, http://www.ebi.ac.uk/efo/EFO_0004307 GCST005166 Genome-wide genotyping array 3344 2018-01-17 29093273 Almgren P 2017-11-02 JCI Insight www.ncbi.nlm.nih.gov/pubmed/29093273 Genetic determinants of circulating GIP and GLP-1 concentrations. Glucagon levels in response to oral glucose tolerance test (120 minutes) 3,344 Swedish ancestry individuals 4,905 Finnish ancestry individuals Illumina [at least 81396] 2 glucagon measurement, glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0008463, http://www.ebi.ac.uk/efo/EFO_0004307 GCST005163 Genome-wide genotyping array 3344 2017-12-05 29064472 Lencer R 2017-10-24 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29064472 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study. Pursuit maintenance gain in psychotic disorders 114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases NA Illumina [4404269] (imputed) 11 pursuit maintenance gain measurement http://www.ebi.ac.uk/efo/EFO_0008433 GCST005028 Genome-wide genotyping array 591 2017-12-05 29064472 Lencer R 2017-10-24 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29064472 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study. Initial pursuit acceleration 114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls NA Illumina [4404269] (imputed) 56 initial pursuit acceleration http://www.ebi.ac.uk/efo/EFO_0008434 GCST005023 Genome-wide genotyping array 849 2017-12-05 29064472 Lencer R 2017-10-24 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29064472 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study. Pursuit maintenance gain 114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls NA Illumina [4404269] (imputed) 111 pursuit maintenance gain measurement http://www.ebi.ac.uk/efo/EFO_0008433 GCST005024 Genome-wide genotyping array 849 2017-12-05 29064472 Lencer R 2017-10-24 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29064472 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study. Anti-saccade response 114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 76 African ancestry controls, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases, 182 European ancestry controls NA Illumina [4404269] (imputed) 41 antisaccade response measurement http://www.ebi.ac.uk/efo/EFO_0006874 GCST005025 Genome-wide genotyping array 849 2017-12-05 29064472 Lencer R 2017-10-24 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29064472 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study. Initial pursuit acceleration in psychotic disorders 114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases. NA Illumina [4404269] (imputed) 22 initial pursuit acceleration http://www.ebi.ac.uk/efo/EFO_0008434 GCST005026 Genome-wide genotyping array 591 2017-12-05 29064472 Lencer R 2017-10-24 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29064472 Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study. Anti-saccade error rate in psychotic disorders 114 African ancestry schizophrenia cases, 69 African schizo-affective cases, 41 African ancestry bipolar disorder cases, 116 European ancestry schizophrenia cases, 86 European ancestry schizo-affective cases, 165 European ancestry bipolar disorder cases NA Illumina [4404269] (imputed) 3 antisaccade response measurement http://www.ebi.ac.uk/efo/EFO_0006874 GCST005027 Genome-wide genotyping array 591 2018-07-04 29499414 Pei YF 2018-02-27 Bone www.ncbi.nlm.nih.gov/pubmed/29499414 Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density. Femoral neck bone mineral density up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals NA Affymetrix, Illumina [7998108] (imputed) 36 femoral neck bone mineral density http://www.ebi.ac.uk/efo/EFO_0007785 GCST005795 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 40491 2018-07-04 29499414 Pei YF 2018-02-27 Bone www.ncbi.nlm.nih.gov/pubmed/29499414 Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density. Lumbar spine bone mineral density up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals NA Affymetrix, Illumina [7998108] (imputed) 34 spine bone mineral density http://www.ebi.ac.uk/efo/EFO_0007701 GCST005796 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 40491 2018-01-12 29095316 Suh Y 2017-11-01 Medicine (Baltimore) www.ncbi.nlm.nih.gov/pubmed/29095316 Genome-wide association study for genetic variants related with maximal voluntary ventilation reveals two novel genomic signals associated with lung function. Lung function (maximal voluntary ventilation) 8,842 Korean ancestry individuals NA Affymetrix [2476376] (imputed) 3 maximal voluntary ventilation, pulmonary function measurement http://www.ebi.ac.uk/efo/EFO_0008431, http://www.ebi.ac.uk/efo/EFO_0003892 GCST005127 Genome-wide genotyping array 8842 2018-01-12 29095316 Suh Y 2017-11-01 Medicine (Baltimore) www.ncbi.nlm.nih.gov/pubmed/29095316 Genome-wide association study for genetic variants related with maximal voluntary ventilation reveals two novel genomic signals associated with lung function. Lung function (forced expiratory volume in 1 second) 8,842 Korean ancestry individuals NA Affymetrix [2476376] (imputed) 2 forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0004314 GCST005132 Genome-wide genotyping array 8842 2018-01-12 29095316 Suh Y 2017-11-01 Medicine (Baltimore) www.ncbi.nlm.nih.gov/pubmed/29095316 Genome-wide association study for genetic variants related with maximal voluntary ventilation reveals two novel genomic signals associated with lung function. Lung function (forced expiratory flow during mid-portion (25% and 75%) of forced vital capacity) 8,842 Korean ancestry individuals NA Affymetrix [2476376] (imputed) 0 maximal midexpiratory flow rate http://www.ebi.ac.uk/efo/EFO_0004313 GCST005129 Genome-wide genotyping array 8842 2018-01-12 29095316 Suh Y 2017-11-01 Medicine (Baltimore) www.ncbi.nlm.nih.gov/pubmed/29095316 Genome-wide association study for genetic variants related with maximal voluntary ventilation reveals two novel genomic signals associated with lung function. Lung function (forced vital capacity) 8,842 Korean ancestry individuals NA Affymetrix [2476376] (imputed) 2 vital capacity http://www.ebi.ac.uk/efo/EFO_0004312 GCST005131 Genome-wide genotyping array 8842 2018-01-12 29095316 Suh Y 2017-11-01 Medicine (Baltimore) www.ncbi.nlm.nih.gov/pubmed/29095316 Genome-wide association study for genetic variants related with maximal voluntary ventilation reveals two novel genomic signals associated with lung function. Lung function (FEV1/FVC) 8,842 Korean ancestry individuals NA Affymetrix [2476376] (imputed) 0 FEV/FEC ratio http://www.ebi.ac.uk/efo/EFO_0004713 GCST005130 Genome-wide genotyping array 8842 2017-11-13 19330027 Ahmed S 2009-05-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19330027 Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Breast cancer 390 European ancestry cases, 364 European ancestry controls 38,430 European ancestry cases, 2,572 East Asian ancestry cases, 41,926 European ancestry controls, 2,059 East Asian ancestry controls Illumina, Perlegen [up to 206586] 2 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST004948 Genome-wide genotyping array 754 2017-11-13 19330027 Ahmed S 2009-05-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19330027 Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Breast cancer 390 European ancestry cases, 364 European ancestry controls 11,645 European ancestry cases, 12,015 European ancestry controls Perlegen [up to 206586] 1 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST004949 Genome-wide genotyping array 754 2017-12-20 29124805 Carlson JC 2017-11-10 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/29124805 Identification of 16q21 as a modifier of nonsyndromic orofacial cleft phenotypes. Orofacial clefts (cleft lip vs. cleft lip and palate) 56 African ancestry cleft lip cases, 121 Asian ancestry cleft lip cases, 128 European ancestry cleft lip cases, 145 Latin/South American cleft lip cases, 91 African ancestry cleft lip with cleft palate cases, 246 Asian ancestry cleft lip with cleft palate cases, 448 European ancestry cleft lip with cleft palate cases, 905 Latin/South American cleft lip with cleft palate cases, 2 cleft lip with cleft palate cases 176 Brazilian ancestry cleft lip cases, 168 Mongolian ancestry cleft lip cases, 16 Filipino ancestry cleft lip cases, 213 European ancestry cleft lip cases, 224 Asian ancestry cleft lip cases, 287 Brazilian ancestry cleft lip with cleft palate cases, 374 Mongolian ancestry cleft lip with cleft palate cases, 64 Filipino ancestry cleft lip with cleft palate cases, 385 European ancestry cleft lip with cleft palate cases, 703 Asian ancestry cleft lip with cleft palate cases. Illumina [10401483] (imputed) 0 Cleft palate, Orofacial clefting syndrome, cleft lip http://purl.obolibrary.org/obo/HP_0000175, http://www.orpha.net/ORDO/Orphanet_139039, http://www.ebi.ac.uk/efo/EFO_0003959 GCST005079 Genome-wide genotyping array 2142 2018-02-02 29082582 Almli LM 2017-10-30 Addict Biol www.ncbi.nlm.nih.gov/pubmed/29082582 Problematic alcohol use associates with sodium channel and clathrin linker 1 (SCLT1) in trauma-exposed populations. Problematic alcohol use in trauma-exposed individuals 1,036 African American individuals 828 European ancestry individuals, 108 African ancestry individuals, 282 Hispanic and Native American individuals, 170 other ancestry individuals, 6 Asian individuals Illumina [501278] 5 alcohol use disorder measurement, response to trauma exposure http://www.ebi.ac.uk/efo/EFO_0009458, http://www.ebi.ac.uk/efo/EFO_0008483 GCST005236 Genome-wide genotyping array 1036 2017-04-20 28012008 Lu S 2016-12-23 J Bone Miner Metab www.ncbi.nlm.nih.gov/pubmed/28012008 Bivariate genome-wide association analyses identified genetic pleiotropic effects for bone mineral density and alcohol drinking in Caucasians. Whole body bone mineral density and alcohol drinking 506 European ancestry males, 1,553 European ancestry females NA Affymetrix [69108] 0 alcohol consumption measurement, bone density http://www.ebi.ac.uk/efo/EFO_0007878, http://www.ebi.ac.uk/efo/EFO_0003923 GCST003921 Genome-wide genotyping array 2059 2017-04-20 28012008 Lu S 2016-12-23 J Bone Miner Metab www.ncbi.nlm.nih.gov/pubmed/28012008 Bivariate genome-wide association analyses identified genetic pleiotropic effects for bone mineral density and alcohol drinking in Caucasians. Hip bone mineral density and alcohol drinking 506 European ancestry males, 1,553 European ancestry females NA Affymetrix [69108] 0 hip bone mineral density, alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0007702, http://www.ebi.ac.uk/efo/EFO_0007878 GCST003920 Genome-wide genotyping array 2059 2017-04-20 28012008 Lu S 2016-12-23 J Bone Miner Metab www.ncbi.nlm.nih.gov/pubmed/28012008 Bivariate genome-wide association analyses identified genetic pleiotropic effects for bone mineral density and alcohol drinking in Caucasians. Spine bone mineral density and alcohol drinking 506 European ancestry males, 1,553 European ancestry females NA Affymetrix [69108] 1 alcohol consumption measurement, spine bone mineral density http://www.ebi.ac.uk/efo/EFO_0007878, http://www.ebi.ac.uk/efo/EFO_0007701 GCST003919 Genome-wide genotyping array 2059 2017-06-20 28274756 Mhatre S 2017-03-03 Lancet Oncol www.ncbi.nlm.nih.gov/pubmed/28274756 Common genetic variation and risk of gallbladder cancer in India: a case-control genome-wide association study. Gallbladder cancer 1,042 Indian ancestry cases, 1,709 Indian ancestry controls 428 Indian ancestry cases, 420 Indian ancestry controls Illumina [10400000] (imputed) 2 gallbladder neoplasm http://www.ebi.ac.uk/efo/EFO_0004606 GCST004201 Genome-wide genotyping array 2751 2017-05-25 28139693 Hoffmann TJ 2017-01-31 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28139693 Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer. Prostate-specific antigen levels 28,503 European ancestry individuals 2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer), 5,603 European ancestry individuals Affymetrix [10109774] (imputed) 40 prostate specific antigen measurement http://www.ebi.ac.uk/efo/EFO_0004624 GCST004093 Genome-wide genotyping array 28503 2017-05-25 28139693 Hoffmann TJ 2017-01-31 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28139693 Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer. Prostate-specific antigen levels (conditioned on lead SNPs) 28,503 European ancestry individuals 2,716 Latino individuals, 2,518 East Asian ancestry individuals, 1,585 African American individuals, 6,193 European ancestry individuals (later diagnosed with prostate cancer) Affymetrix [10109774] (imputed) 21 prostate specific antigen measurement http://www.ebi.ac.uk/efo/EFO_0004624 GCST004094 Genome-wide genotyping array 28503 2017-03-31 27694959 Bonder MJ 2016-10-03 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27694959 The effect of host genetics on the gut microbiome. Gut microbiota (functional units) 984 European ancestry individuals 530 European ancestry individuals Illumina [8100000] (imputed) 56 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST003854 Genome-wide genotyping array 984 2017-03-31 27694959 Bonder MJ 2016-10-03 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27694959 The effect of host genetics on the gut microbiome. Gut microbiota (bacterial taxa) 984 European ancestry individuals 530 European ancestry individuals Illumina [8100000] (imputed) 21 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST003855 Genome-wide genotyping array 984 2017-05-11 27182965 Pickrell JK 2016-05-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27182965 Detection and interpretation of shared genetic influences on 42 human traits. Parkinson's disease 9,619 European ancestry cases, 324,522 European ancestry controls NA Illumina [12438219] (imputed) 25 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST003984 Genome-wide genotyping array 334141 2017-05-11 27182965 Pickrell JK 2016-05-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27182965 Detection and interpretation of shared genetic influences on 42 human traits. Breast size 33,790 European ancestry individuals NA Illumina [12039487] (imputed) 23 breast size http://www.ebi.ac.uk/efo/EFO_0004884 GCST003985 Genome-wide genotyping array 33790 2017-05-11 27182965 Pickrell JK 2016-05-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27182965 Detection and interpretation of shared genetic influences on 42 human traits. Migraine 53,109 European ancestry cases, 230,876 European ancestry controls NA Illumina [13763073] (imputed) 27 migraine disorder http://www.ebi.ac.uk/efo/EFO_0003821 GCST003986 Genome-wide genotyping array 283985 2017-05-11 27182965 Pickrell JK 2016-05-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27182965 Detection and interpretation of shared genetic influences on 42 human traits. Asthma 28,399 European ancestry cases, 128,843 European ancestry controls NA Illumina [13747813] (imputed) 27 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST003987 Genome-wide genotyping array 157242 2017-05-11 27182965 Pickrell JK 2016-05-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27182965 Detection and interpretation of shared genetic influences on 42 human traits. Hypothyroidism 17,558 European ancestry cases, 117,083 European ancestry controls NA Illumina [13676411] (imputed) 26 hypothyroidism http://www.ebi.ac.uk/efo/EFO_0004705 GCST003988 Genome-wide genotyping array 134641 2017-05-11 27182965 Pickrell JK 2016-05-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27182965 Detection and interpretation of shared genetic influences on 42 human traits. Chin dimples 58,032 European ancestry cases, 13,457 European ancestry controls NA Illumina [13537761] (imputed) 46 chin morphology measurement http://www.ebi.ac.uk/efo/EFO_0007842 GCST003989 Genome-wide genotyping array 71489 2017-05-11 27182965 Pickrell JK 2016-05-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27182965 Detection and interpretation of shared genetic influences on 42 human traits. Allergy 66,973 European ancestry cases, 113,768 European ancestry controls NA Illumina [12845910] (imputed) 26 allergy http://www.ebi.ac.uk/efo/EFO_0003785 GCST003990 Genome-wide genotyping array 180741 2017-05-11 27182965 Pickrell JK 2016-05-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27182965 Detection and interpretation of shared genetic influences on 42 human traits. Childhood ear infection 46,936 European ancestry cases, 74,874 European ancestry controls NA Illumina [13754664] (imputed) 24 susceptibility to childhood ear infection measurement http://www.ebi.ac.uk/efo/EFO_0007904 GCST003991 Genome-wide genotyping array 121810 2017-05-11 27182965 Pickrell JK 2016-05-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27182965 Detection and interpretation of shared genetic influences on 42 human traits. Photic sneeze reflex 32,446 European ancestry cases, 67,249 European ancestry controls NA Illumina [13729857] (imputed) 50 autosomal dominant compelling helio-ophthalmic outburst syndrome http://www.ebi.ac.uk/efo/EFO_0007887 GCST003992 Genome-wide genotyping array 99695 2017-05-11 27182965 Pickrell JK 2016-05-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27182965 Detection and interpretation of shared genetic influences on 42 human traits. Menarche (age at onset) 76,831 European ancestry individuals NA Illumina [12039492] 44 age at menarche http://www.ebi.ac.uk/efo/EFO_0004703 GCST003993 Genome-wide genotyping array 76831 2017-05-11 27182965 Pickrell JK 2016-05-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27182965 Detection and interpretation of shared genetic influences on 42 human traits. Age at voice drop 55,871 European ancestry individuals NA Illumina [12039491] 14 age at voice drop http://www.ebi.ac.uk/efo/EFO_0007888 GCST003994 Genome-wide genotyping array 55871 2017-05-11 27182965 Pickrell JK 2016-05-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27182965 Detection and interpretation of shared genetic influences on 42 human traits. Tonsillectomy 60,098 European ancestry cases, 113,323 European ancestry controls NA Illumina [13757430] (imputed) 36 tonsillectomy risk measurement http://www.ebi.ac.uk/efo/EFO_0007924 GCST003995 Genome-wide genotyping array 173421 2017-05-11 27182965 Pickrell JK 2016-05-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27182965 Detection and interpretation of shared genetic influences on 42 human traits. Monobrow 69,284 European ancestry individuals NA Illumina [12039491] (imputed) 50 synophrys measurement http://www.ebi.ac.uk/efo/EFO_0007906 GCST003996 Genome-wide genotyping array 69284 2017-05-11 27182965 Pickrell JK 2016-05-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27182965 Detection and interpretation of shared genetic influences on 42 human traits. Myopia 106,086 European ancestry cases, 85,757 European ancestry controls NA Illumina [13762925] (imputed) 51 Myopia http://purl.obolibrary.org/obo/HP_0000545 GCST003997 Genome-wide genotyping array 191843 2017-05-11 27182965 Pickrell JK 2016-05-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27182965 Detection and interpretation of shared genetic influences on 42 human traits. Joint mobility (Beighton score) 64,143 European ancestry individuals NA Illumina [12039492] (imputed) 25 joint hypermobility measurement http://www.ebi.ac.uk/efo/EFO_0007905 GCST003998 Genome-wide genotyping array 64143 2017-05-11 27182965 Pickrell JK 2016-05-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27182965 Detection and interpretation of shared genetic influences on 42 human traits. Nose size 67,023 European ancestry individuals NA Illumina [12039491] (imputed) 25 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST003999 Genome-wide genotyping array 67023 2017-05-11 27182965 Pickrell JK 2016-05-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27182965 Detection and interpretation of shared genetic influences on 42 human traits. Male-pattern baldness 9,009 European ancestry cases, 8,491 European ancestry controls NA Illumina [13436641] (imputed) 44 androgenetic alopecia http://www.ebi.ac.uk/efo/EFO_0004191 GCST003983 Genome-wide genotyping array 17500 2017-09-05 28394258 Wild PS 2017-04-10 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/28394258 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. Peak velocity of the mitral E-wave 21,852 European ancestry individuals 14,787 European ancestry individuals Affymetrix, Illumina [at least 283291] (imputed) 0 left ventricular diastolic function measurement http://www.ebi.ac.uk/efo/EFO_0008204 GCST004653 Genome-wide genotyping array 21852 2017-09-05 28394258 Wild PS 2017-04-10 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/28394258 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. Isovolumetric relaxation time 21,852 European ancestry individuals 14,787 European ancestry individuals Affymetrix, Illumina [at least 283291] (imputed) 5 left ventricular diastolic function measurement http://www.ebi.ac.uk/efo/EFO_0008204 GCST004649 Genome-wide genotyping array 21852 2017-09-05 28394258 Wild PS 2017-04-10 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/28394258 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. Peak velocity of excursion of lateral mitral annulus in early diastolic phase 21,852 European ancestry individuals 14,787 European ancestry individuals Affymetrix, Illumina [at least 283291] (imputed) 0 left ventricular diastolic function measurement http://www.ebi.ac.uk/efo/EFO_0008204 GCST004658 Genome-wide genotyping array 21852 2017-09-05 28394258 Wild PS 2017-04-10 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/28394258 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. Peak velocity of the mitral A-wave 21,852 European ancestry individuals 14,787 European ancestry individuals Affymetrix, Illumina [at least 283291] (imputed) 2 left ventricular diastolic function measurement http://www.ebi.ac.uk/efo/EFO_0008204 GCST004652 Genome-wide genotyping array 21852 2017-09-05 28394258 Wild PS 2017-04-10 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/28394258 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave. 21,852 European ancestry individuals 14,787 European ancestry individuals Affymetrix, Illumina [at least 283291] (imputed) 1 left ventricular diastolic function measurement http://www.ebi.ac.uk/efo/EFO_0008204 GCST004656 Genome-wide genotyping array 21852 2017-09-05 28394258 Wild PS 2017-04-10 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/28394258 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. Deceleration time of the mitral E-wave 21,852 European ancestry individuals 14,787 European ancestry individuals Affymetrix, Illumina [at least 283291] (imputed) 0 left ventricular diastolic function measurement http://www.ebi.ac.uk/efo/EFO_0008204 GCST004654 Genome-wide genotyping array 21852 2017-09-05 28394258 Wild PS 2017-04-10 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/28394258 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. Ratio of the peak velocity of the excursion of the lateral mitral annulus in the early diastolic phase and the peak velocity of the mitral E-wave 21,852 European ancestry individuals 14,787 European ancestry individuals Affymetrix, Illumina [at least 283291] (imputed) 0 left ventricular diastolic function measurement http://www.ebi.ac.uk/efo/EFO_0008204 GCST004657 Genome-wide genotyping array 21852 2017-09-05 28394258 Wild PS 2017-04-10 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/28394258 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. Diastolic dysfunction with preserved ejection pressure 21,852 European ancestry individuals 14,787 European ancestry individuals Affymetrix, Illumina [at least 283291] (imputed) 0 left ventricular diastolic function measurement http://www.ebi.ac.uk/efo/EFO_0008204 GCST004650 Genome-wide genotyping array 21852 2017-09-05 28394258 Wild PS 2017-04-10 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/28394258 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. Heart failure with preserved ejection fraction 21,852 European ancestry individuals 14,787 European ancestry individuals Affymetrix, Illumina [at least 283291] (imputed) 0 left ventricular diastolic function measurement http://www.ebi.ac.uk/efo/EFO_0008204 GCST004660 Genome-wide genotyping array 21852 2017-09-05 28394258 Wild PS 2017-04-10 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/28394258 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. Aortic root size 30,201 European ancestry individuals 14,002 European ancestry individuals Affymetrix, Illumina [at least 283291] (imputed) 8 aortic root size http://www.ebi.ac.uk/efo/EFO_0005037 GCST004651 Genome-wide genotyping array 30201 2017-09-05 28394258 Wild PS 2017-04-10 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/28394258 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. Left atrial antero-posterior diameter 30,201 European ancestry individuals NA Affymetrix, Illumina [at least 283291] (imputed) 16 left ventricular structural measurement http://www.ebi.ac.uk/efo/EFO_0008205 GCST004647 Genome-wide genotyping array 30201 2017-09-05 28394258 Wild PS 2017-04-10 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/28394258 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. Left ventricle diastolic internal dimension 30,201 European ancestry individuals 14,002 European ancestry individuals Affymetrix, Illumina [at least 283291] (imputed) 2 left ventricular structural measurement http://www.ebi.ac.uk/efo/EFO_0008205 GCST004655 Genome-wide genotyping array 30201 2017-09-05 28394258 Wild PS 2017-04-10 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/28394258 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. Left ventricle wall thickness 30,201 European ancestry individuals NA Affymetrix, Illumina [at least 283291] (imputed) 21 left ventricular structural measurement http://www.ebi.ac.uk/efo/EFO_0008205 GCST004646 Genome-wide genotyping array 30201 2017-09-05 28394258 Wild PS 2017-04-10 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/28394258 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. Left ventricular mass 30,201 European ancestry individuals 14,002 European ancestry individuals Affymetrix, Illumina [at least 283291] (imputed) 1 left ventricular structural measurement http://www.ebi.ac.uk/efo/EFO_0008205 GCST004659 Genome-wide genotyping array 30201 2017-09-05 28394258 Wild PS 2017-04-10 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/28394258 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. Left ventricular fractional shortening 30,201 European ancestry individuals 14,002 European ancestry individuals Affymetrix, Illumina [at least 283291] (imputed) 1 left ventricular systolic function measurement http://www.ebi.ac.uk/efo/EFO_0008206 GCST004645 Genome-wide genotyping array 30201 2017-09-05 28394258 Wild PS 2017-04-10 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/28394258 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. Left ventricle systolic dysfunction 30,201 European ancestry individuals NA Affymetrix, Illumina [at least 283291] (imputed) 6 left ventricular systolic function measurement http://www.ebi.ac.uk/efo/EFO_0008206 GCST004648 Genome-wide genotyping array 30201 2017-04-24 27846281 Galesloot TE 2016-11-15 PLoS One www.ncbi.nlm.nih.gov/pubmed/27846281 Meta-GWAS and Meta-Analysis of Exome Array Studies Do Not Reveal Genetic Determinants of Serum Hepcidin. Hepcidin/transferrin saturation ratio 1495 European ancestry individuals without iron deficiency or clinical inflammation, 324 European ancestry individuals, 1206 Val Borbera (founder/genetic isolated) individuals without iron deficiency or clinical inflammation, 274 Val Borbera (founder/genetic isolated) individuals, 2,695 European ancestry individuals without iron deficiency or clinical inflammation, 207 individuals NA Illumina [up to 38043574] (imputed) 13 hepcidin:transferrin saturation ratio http://www.ebi.ac.uk/efo/EFO_0007902 GCST003945 Genome-wide genotyping array 6201 2017-04-24 27846281 Galesloot TE 2016-11-15 PLoS One www.ncbi.nlm.nih.gov/pubmed/27846281 Meta-GWAS and Meta-Analysis of Exome Array Studies Do Not Reveal Genetic Determinants of Serum Hepcidin. Hepcidin/ferritin ratio 1495 European ancestry individuals without iron deficiency or clinical inflammation, 324 European ancestry individuals, 1206 Val Borbera (founder/genetic isolated) individuals without iron deficiency or clinical inflammation, 274 Val Borbera (founder/genetic isolated) individuals, 2,695 European ancestry individuals without iron deficiency or clinical inflammation, 207 individuals NA Illumina [up to 38043574] (imputed) 43 hepcidin:ferritin ratio http://www.ebi.ac.uk/efo/EFO_0007901 GCST003944 Genome-wide genotyping array 6201 2017-04-24 27846281 Galesloot TE 2016-11-15 PLoS One www.ncbi.nlm.nih.gov/pubmed/27846281 Meta-GWAS and Meta-Analysis of Exome Array Studies Do Not Reveal Genetic Determinants of Serum Hepcidin. Hepcidin levels 1495 European ancestry individuals without iron deficiency or clinical inflammation, 324 European ancestry individuals, 1206 Val Borbera (founder/genetic isolated) individuals without iron deficiency or clinical inflammation, 274 Val Borbera (founder/genetic isolated) individuals, 2,695 European ancestry individuals without iron deficiency or clinical inflammation, 207 individuals 1,018 European ancestry individuals, 2,876 individuals Illumina [up to 38043574] (imputed) 7 serum hepcidin measurement http://www.ebi.ac.uk/efo/EFO_0004504 GCST003943 Genome-wide genotyping array 6201 2017-05-24 28087736 Ludwig KU 2017-01-13 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28087736 Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only. Nonsyndromic cleft lip with or without cleft palate 399 European ancestry cases, 1,318 European ancestry controls, 666 European ancestry trios, 795 Asian trios 224 European ancestry cases, 921 European ancestry controls, 152 Mayan cases, 323 Mayan controls, 198 Middle Eastern cases, 391 Middle Eastern controls NR [8012124] (imputed) 13 Cleft palate, cleft lip http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959 GCST004088 Genome-wide genotyping array 3178 2017-05-24 28087736 Ludwig KU 2017-01-13 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28087736 Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only. Cleft palate 550 European, Asian and unknown trios NA NR [~ 8380000] (imputed) 0 Cleft palate http://purl.obolibrary.org/obo/HP_0000175 GCST004089 Genome-wide genotyping array 550 2017-05-30 28167838 Deckert J 2017-02-07 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/28167838 GLRB allelic variation associated with agoraphobic cognitions, increased startle response and fear network activation: a potential neurogenetic pathway to panic disorder. Agoraphobic traits 1,370 German ancestry individuals 6,392 European ancestry individuals Illumina [7071105] (imputed) 0 agoraphobia symptom measurement http://www.ebi.ac.uk/efo/EFO_0007945 GCST004109 Genome-wide genotyping array 1370 2017-06-29 28207573 Backman JD 2017-04-01 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/28207573 Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response. Clopidogrel active metabolite levels 513 Amish individuals NA Affymetrix [7884700] (imputed) 27 clopidogrel metabolite measurement http://www.ebi.ac.uk/efo/EFO_0007966 GCST004264 Genome-wide genotyping array 513 2017-06-29 28207573 Backman JD 2017-04-01 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/28207573 Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response. Response to clopidogrel therapy 513 Amish individuals NA Affymetrix [7884700] (imputed) 1 platelet reactivity measurement, response to clopidogrel http://www.ebi.ac.uk/efo/EFO_0004985, http://purl.obolibrary.org/obo/GO_1903493 GCST004266 Genome-wide genotyping array 513 2017-06-26 28283553 Srinivasan L 2017-03-10 Arch Dis Child Fetal Neonatal Ed www.ncbi.nlm.nih.gov/pubmed/28283553 Genome-wide association study of sepsis in extremely premature infants. Sepsis in extremely premature infants 155 European ancestry cases, 190 non-European ancestry cases, 184 European ancestry controls, 222 non-European ancestry controls NA Illumina [7200000] (imputed) 6 Neonatal sepsis http://purl.obolibrary.org/obo/HP_0040187 GCST004230 Genome-wide genotyping array 751 2017-06-06 28212542 Ransohoff KJ 2017-02-09 Oncotarget www.ncbi.nlm.nih.gov/pubmed/28212542 Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma. Melanoma 4,842 European ancestry cases, 286,565 European ancestry controls 1,804 European ancestry cases, 1,026 European ancestry controls Illumina [at least 560000] (imputed) 28 melanoma http://www.ebi.ac.uk/efo/EFO_0000756 GCST004142 Genome-wide genotyping array 291407 2017-05-30 28167095 Forno E 2017-02-04 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/28167095 Genome-wide interaction study of dust mite allergen on lung function in children with asthma. Lung function (FEV1/FVC) in asthma (dust mite allergen exposure interaction) 440 Puerto Rican ancestry child cases 497 European ancestry child cases, 605 Hispanic child cases Illumina [1830000] (imputed) 2 allergen exposure measurement, FEV/FEC ratio http://www.ebi.ac.uk/efo/EFO_0007944, http://www.ebi.ac.uk/efo/EFO_0004713 GCST004108 Genome-wide genotyping array 440 2017-05-30 28167095 Forno E 2017-02-04 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/28167095 Genome-wide interaction study of dust mite allergen on lung function in children with asthma. Lung function (FEV1) in asthma (dust mite allergen exposure interaction) 440 Puerto Rican ancestry child cases 497 European ancestry child cases, 605 Hispanic child cases Illumina [1830000] (imputed) 5 forced expiratory volume, allergen exposure measurement http://www.ebi.ac.uk/efo/EFO_0004314, http://www.ebi.ac.uk/efo/EFO_0007944 GCST004107 Genome-wide genotyping array 440 2017-05-30 28044437 McDonald MN 2017-01-02 J Cachexia Sarcopenia Muscle www.ncbi.nlm.nih.gov/pubmed/28044437 Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1. Body mass index (change over time) in gastrointestinal cancer or chronic obstructive pulmonary disease 237 COPD cases, 204 GI cancer cases NA Affymetrix [418365] 4 longitudinal BMI measurement http://www.ebi.ac.uk/efo/EFO_0005937 GCST004100 Genome-wide genotyping array 441 2017-05-30 28044437 McDonald MN 2017-01-02 J Cachexia Sarcopenia Muscle www.ncbi.nlm.nih.gov/pubmed/28044437 Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1. Body mass index (change over time) in cancer or chronic obstructive pulmonary disease 1,085 cancer cases, 237 COPD cases NA Affymetrix [418365] 3 longitudinal BMI measurement http://www.ebi.ac.uk/efo/EFO_0005937 GCST004103 Genome-wide genotyping array 1322 2017-05-30 28044437 McDonald MN 2017-01-02 J Cachexia Sarcopenia Muscle www.ncbi.nlm.nih.gov/pubmed/28044437 Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1. Body mass index (change over time) in lung cancer 112 cases NA Affymetrix [418365] 3 longitudinal BMI measurement http://www.ebi.ac.uk/efo/EFO_0005937 GCST004104 Genome-wide genotyping array 112 2017-05-30 28044437 McDonald MN 2017-01-02 J Cachexia Sarcopenia Muscle www.ncbi.nlm.nih.gov/pubmed/28044437 Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1. Body mass index (change over time) in gastrointestinal cancer 204 cases NA Affymetrix [418365] 3 longitudinal BMI measurement http://www.ebi.ac.uk/efo/EFO_0005937 GCST004101 Genome-wide genotyping array 204 2017-05-30 28044437 McDonald MN 2017-01-02 J Cachexia Sarcopenia Muscle www.ncbi.nlm.nih.gov/pubmed/28044437 Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1. Body mass index (change over time) in chronic obstructive pulmonary disease 237 cases NA Affymetrix [418365] 6 longitudinal BMI measurement http://www.ebi.ac.uk/efo/EFO_0005937 GCST004105 Genome-wide genotyping array 237 2017-05-30 28044437 McDonald MN 2017-01-02 J Cachexia Sarcopenia Muscle www.ncbi.nlm.nih.gov/pubmed/28044437 Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1. Body mass index (change over time) in lung cancer or chronic obstructive pulmonary disease 112 lung cancer cases, 237 COPD cases NA Affymetrix [418365] 5 longitudinal BMI measurement http://www.ebi.ac.uk/efo/EFO_0005937 GCST004102 Genome-wide genotyping array 349 2017-05-30 28044437 McDonald MN 2017-01-02 J Cachexia Sarcopenia Muscle www.ncbi.nlm.nih.gov/pubmed/28044437 Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1. Body mass index (change over time) in cancer 1,085 cases NA Affymetrix [418365] 1 longitudinal BMI measurement http://www.ebi.ac.uk/efo/EFO_0005937 GCST004106 Genome-wide genotyping array 1085 2017-03-24 27670767 Chang SW 2016-09-27 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/27670767 Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes. Diabetes in response to antihypertensive drug treatment (treatment strategy interaction) 138 European American hypertensive cases with diabetes, 414 European American hypertensive cases without diabetes 157 Hispanic hypertensive cases with diabetes, 314 Hispanic hypertensive cases without diabetes, 39 African American hypertensive cases with diabetes, 78 African American hypertensive cases without diabetes Illumina [NR] (imputed) 3 response to antihypertensive drug, diabetes mellitus, response to beta blocker, response to calcium channel blocker http://www.ebi.ac.uk/efo/EFO_0005405, http://www.ebi.ac.uk/efo/EFO_0000400, http://www.ebi.ac.uk/efo/EFO_0007766, http://www.ebi.ac.uk/efo/EFO_0007767 GCST003797 Genome-wide genotyping array 552 2017-03-16 27670397 Reyes-Gibby CC 2016-09-27 Sci Rep www.ncbi.nlm.nih.gov/pubmed/27670397 Genome-wide association study suggests common variants within RP11-634B7.4 gene influencing severe pre-treatment pain in head and neck cancer patients. Pre-treatment pain in head and neck squamous cell carcinoma 148 European ancestry cases, 810 European ancestry controls 58 European ancestry cases, 352 European ancestry controls Illumina [714494] 9 pain http://www.ebi.ac.uk/efo/EFO_0003843 GCST003760 Genome-wide genotyping array 958 2017-03-20 27623749 Hwang JY 2016-09-14 Sci Rep www.ncbi.nlm.nih.gov/pubmed/27623749 An integrative study identifies KCNC2 as a novel predisposing factor for childhood obesity and the risk of diabetes in the Korean population. Body mass index 484 Korean ancestry children 10,390 Korean ancestry individuals Illumina [357789] (imputed) 0 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST003789 Genome-wide genotyping array 484 2017-03-27 27798624 Eppinga RN 2016-10-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27798624 Identification of genomic loci associated with resting heart rate and shared genetic predictors with all-cause mortality. Resting heart rate 127,919 European ancestry individuals, 2,478 Asian ancestry individuals, 1,734 Black individuals, 684 Mixed ancestry individuals, 1,436 individuals 130,795 European ancestry individuals Affymetrix [19941912] (imputed) 86 resting heart rate http://www.ebi.ac.uk/efo/EFO_0004351 GCST003818 Genome-wide genotyping array 134251 2017-03-21 27671213 Petros Z 2016-09-26 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/27671213 Genome-wide association and replication study of anti-tuberculosis drugs-induced liver toxicity. Liver injury in anti-tuberculosis drug treatment 48 Ethiopian cases with liver injury, 354 Ethiopian cases without liver injury 27 Ethiopian cases with liver injury, 217 Ethiopian cases without liver injury Illumina [660206] 2 response to rifampicin, drug-induced liver injury http://www.ebi.ac.uk/efo/EFO_0007866, http://www.ebi.ac.uk/efo/EFO_0004228 GCST003792 Genome-wide genotyping array 402 2017-03-06 27671502 Blokland GAM 2016-09-23 Int J Psychophysiol www.ncbi.nlm.nih.gov/pubmed/27671502 Genome-wide association study of working memory brain activation. Brain activation in response to working memory task 679 European ancestry individuals 97 unknown ancestry individuals Illumina [529379] 0 memory performance, functional brain measurement, short-term memory http://www.ebi.ac.uk/efo/EFO_0004874, http://www.ebi.ac.uk/efo/EFO_0007849, http://www.ebi.ac.uk/efo/EFO_0004335 GCST003698 Genome-wide genotyping array 679 2017-03-31 27647854 Sandholm N 2016-09-19 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/27647854 The Genetic Landscape of Renal Complications in Type 1 Diabetes. Kidney disease (end stage renal disease vs non-end stage renal disease) in type 1 diabetes 729 European ancestry cases, 84 cases, 3,290 European ancestry controls, 705 controls 94 European ancestry cases, 964 cases, 993 European ancestry controls, 4806 controls Illumina [NR] (imputed) 2 chronic kidney disease, diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0003884, http://www.ebi.ac.uk/efo/EFO_0000401 GCST003862 Genome-wide genotyping array 4808 2017-03-31 27647854 Sandholm N 2016-09-19 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/27647854 The Genetic Landscape of Renal Complications in Type 1 Diabetes. Kidney disease (end stage renal disease vs normoalbuminuria) in type 1 diabetes 729 European ancestry cases, 84 cases, 1,903 European ancestry controls, 491 controls 94 European ancestry cases, 964 cases, 627 European ancestry controls, 3187 controls Illumina [NR] (imputed) 1 chronic kidney disease, diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0003884, http://www.ebi.ac.uk/efo/EFO_0000401 GCST003861 Genome-wide genotyping array 3207 2017-03-31 27647854 Sandholm N 2016-09-19 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/27647854 The Genetic Landscape of Renal Complications in Type 1 Diabetes. Chronic kidney disease (severe chronic kidney disease vs normal kidney function) in type 1 diabetes 907 European ancestry cases, 210 cases, 1,661 European ancestry controls, 357 controls 1,266 cases, 2,655 controls Illumina [NR] (imputed) 2 chronic kidney disease, diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0003884, http://www.ebi.ac.uk/efo/EFO_0000401 GCST003863 Genome-wide genotyping array 3135 2017-03-31 27647854 Sandholm N 2016-09-19 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/27647854 The Genetic Landscape of Renal Complications in Type 1 Diabetes. Kidney disease (early and late stages) in type 1 diabetes 2,068 European ancestry cases, 495 cases, 1,903 European ancestry controls, 690 controls 68 European ancestry cases, 3,188 cases, 815 European ancestry controls, 3,907 controls Illumina [NR] (imputed) 1 chronic kidney disease, diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0003884, http://www.ebi.ac.uk/efo/EFO_0000401 GCST003864 Genome-wide genotyping array 5156 2017-03-31 27647854 Sandholm N 2016-09-19 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/27647854 The Genetic Landscape of Renal Complications in Type 1 Diabetes. Kidney disease (early stage) in type 1 diabetes 555 European ancestry cases, 245 cases, 1,903 European ancestry controls, 690 controls 602 cases, 1,459 controls Illumina [NR] (imputed) 3 chronic kidney disease, diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0003884, http://www.ebi.ac.uk/efo/EFO_0000401 GCST003865 Genome-wide genotyping array 3393 2017-03-31 27647854 Sandholm N 2016-09-19 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/27647854 The Genetic Landscape of Renal Complications in Type 1 Diabetes. Kidney disease (late stage) in type 1 diabetes 1,507 European ancestry cases, 250 controls, 1,903 European ancestry controls, 690 controls 2,536 cases, 3,907 controls Illumina [NR] (imputed) 1 chronic kidney disease, diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0003884, http://www.ebi.ac.uk/efo/EFO_0000401 GCST003866 Genome-wide genotyping array 4350 2017-03-31 27647854 Sandholm N 2016-09-19 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/27647854 The Genetic Landscape of Renal Complications in Type 1 Diabetes. Chronic kidney disease (chronic kidney disease vs normal or mildly reduced eGFR) in type 1 diabetes 1,142 European ancestry cases, 113 cases, 2,442 European ancestry controls, 467 controls 2,046 cases, 4,549 controls Illumina [NR] (imputed) 1 chronic kidney disease, diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0003884, http://www.ebi.ac.uk/efo/EFO_0000401 GCST003867 Genome-wide genotyping array 4164 2017-03-31 28171582 Gao X 2016-11-15 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28171582 Genome-wide association study identifies WNT7B as a novel locus for central corneal thickness in Latinos. Central corneal thickness 3,584 Latino individuals 931 Latino individuals Illumina [576798] (imputed) 6 central corneal thickness http://www.ebi.ac.uk/efo/EFO_0005213 GCST003856 Genome-wide genotyping array 3584 2019-02-10 27841878 Hoffmann TJ 2016-11-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27841878 Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation. Diastolic blood pressure 295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals NA Affymetrix [at least 2696785] (imputed) 237 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST007094 Genome-wide genotyping array 321262 2019-02-10 27841878 Hoffmann TJ 2016-11-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27841878 Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation. Pulse pressure 295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals NA Affymetrix [at least 2696785] (imputed) 257 pulse pressure measurement http://www.ebi.ac.uk/efo/EFO_0005763 GCST007096 Genome-wide genotyping array 321262 2019-02-10 27841878 Hoffmann TJ 2016-11-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27841878 Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation. Systolic blood pressure 295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals NA Affymetrix [at least 2696785] (imputed) 260 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST007099 Genome-wide genotyping array 321262 2019-02-10 27841878 Hoffmann TJ 2016-11-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27841878 Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation. Diastolic blood pressure 80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals NA Affymetrix [at least 2696785] (imputed) 127 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST007098 Genome-wide genotyping array 99785 2019-02-10 27841878 Hoffmann TJ 2016-11-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27841878 Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation. Pulse pressure 80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals NA Affymetrix [at least 2696785] (imputed) 169 pulse pressure measurement http://www.ebi.ac.uk/efo/EFO_0005763 GCST007097 Genome-wide genotyping array 99785 2019-02-10 27841878 Hoffmann TJ 2016-11-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27841878 Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation. Systolic blood pressure 80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals NA Affymetrix [at least 2696785] (imputed) 144 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST007095 Genome-wide genotyping array 99785 2017-05-11 28098162 Hibar DP 2017-01-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28098162 Novel genetic loci associated with hippocampal volume. Hippocampal volume 26,814 European ancestry individuals up to 3,863 European ancestry individuals, up to 562 African American individuals, up to 886 Asian ancestry individuals, up to 1,411 Mexican American individuals Affymetrix, Illumina, Perlegen [NR] (imputed) 2 hippocampal volume http://www.ebi.ac.uk/efo/EFO_0005035 GCST003961 Genome-wide genotyping array 26814 2017-06-06 28195142 Gudmundsson J 2017-02-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28195142 A genome-wide association study yields five novel thyroid cancer risk loci. Thyroid cancer 2,637 European ancestry cases, 364 non-array typed, familial imputed Icelandic ancestry cases, 134,811 European ancestry controls, 152,739 non-array typed, familial imputed Icelandic ancestry controls. NA Illumina [7100000] (imputed) 12 thyroid carcinoma http://www.ebi.ac.uk/efo/EFO_0002892 GCST004144 Genome-wide genotyping array 290551 2017-06-14 28295283 Wang H 2017-03-13 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/28295283 Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans. Colorectal cancer 1,894 African American ancestry cases, 4,703 African American ancestry controls. 891 African American ancestry cases, 1,150 African American ancestry controls, 1,611 Hispanic ancestry cases, 4,330 Hispanic ancestry controls. Illumina [10050748] (imputed) 2 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST004168 Genome-wide genotyping array 6597 2017-06-14 28295283 Wang H 2017-03-13 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/28295283 Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans. Rectal cancer 443 African American ancestry cases, 4,703 African American ancestry controls. 284 African American ancestry cases, 1,150 African American ancestry controls Illumina [10050748] (imputed) 0 rectum cancer http://www.ebi.ac.uk/efo/EFO_1000657 GCST004169 Genome-wide genotyping array 5146 2017-06-14 28295283 Wang H 2017-03-13 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/28295283 Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans. Colon cancer 1,451 African American ancestry cases, 4,703 African American ancestry controls. 607 African American ancestry cases, 1,146 African American ancestry controls. Illumina [10050748] (imputed) 2 colonic neoplasm http://www.ebi.ac.uk/efo/EFO_0004288 GCST004167 Genome-wide genotyping array 6154 2017-07-13 28298293 Hu Y 2017-03-15 J Lipid Res www.ncbi.nlm.nih.gov/pubmed/28298293 Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations. Palmitoleic acid (16:1n-7) levels 3,521 Chinese ancestry individuals, European individuals (see Wu 2013). NA Affymetrix, Illumina [~ 2200000] (imputed) 4 palmitoleic acid measurement http://www.ebi.ac.uk/efo/EFO_0007973 GCST004339 Genome-wide genotyping array 5534 2017-07-13 28298293 Hu Y 2017-03-15 J Lipid Res www.ncbi.nlm.nih.gov/pubmed/28298293 Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations. Vaccenic acid (18:1n-7) levels 3,521 Chinese ancestry individuals, 12,020 European ancestry individuals NA Affymetrix, Illumina [2200000] (imputed) 4 vaccenic acid measurement http://www.ebi.ac.uk/efo/EFO_0007974 GCST004342 Genome-wide genotyping array 15541 2017-07-13 28298293 Hu Y 2017-03-15 J Lipid Res www.ncbi.nlm.nih.gov/pubmed/28298293 Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations. Oleic acid (18:1n-9) levels 3,521 Chinese ancestry individuals, European ancestry individuals (see Wu et al 2013) NA Affymetrix, Illumina [2200000] (imputed) 4 oleic acid measurement http://www.ebi.ac.uk/efo/EFO_0006810 GCST004338 Genome-wide genotyping array 5534 2017-07-13 28298293 Hu Y 2017-03-15 J Lipid Res www.ncbi.nlm.nih.gov/pubmed/28298293 Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations. Gondoic acid (20:1n-9) levels 3,521 Chinese ancestry individuals, 12,020 European ancestry individuals NA Affymetrix, Illumina [2200000] (imputed) 4 gondoic acid measurement http://www.ebi.ac.uk/efo/EFO_0007975 GCST004337 Genome-wide genotyping array 15541 2017-07-13 28298293 Hu Y 2017-03-15 J Lipid Res www.ncbi.nlm.nih.gov/pubmed/28298293 Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations. Erucic acid (22:1n-9) levels 3,521 Chinese ancestry individuals, 12,020 European ancestry individuals NA Affymetrix, Illumina [2200000] (imputed) 0 erucic acid measurement http://www.ebi.ac.uk/efo/EFO_0007976 GCST004340 Genome-wide genotyping array 15541 2017-07-13 28298293 Hu Y 2017-03-15 J Lipid Res www.ncbi.nlm.nih.gov/pubmed/28298293 Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations. Nervonic acid (24:1n-9) levels 3,521 Chinese ancestry individuals, 12,020 European ancestry individuals NA Affymetrix, Illumina [2200000] (imputed) 0 nervonic acid measurement http://www.ebi.ac.uk/efo/EFO_0007977 GCST004341 Genome-wide genotyping array 15541 2017-06-21 28322352 Ran S 2017-03-21 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28322352 Gene-based genome-wide association study identified 19p13.3 for lean body mass. Lean body mass 1,000 European ancestry individuals 2,283 European ancestry individuals Affymetrix [up to 379319] (imputed) 0 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST004218 Genome-wide genotyping array 1000 2017-03-31 27659466 van der Harst P 2016-09-27 J Am Coll Cardiol www.ncbi.nlm.nih.gov/pubmed/27659466 52 Genetic Loci Influencing Myocardial Mass. QRS duration 59,565 European ancestry individuals, 690 Orcadian (founder/genetic isolate) individuals 13,263 European ancestry individuals, 3,603 African American individuals, 4,619 Indian ancestry individuals Affymetrix, Illumina, Perlegen [at least 2766983] (imputed) 47 QRS complex, QRS duration http://www.ebi.ac.uk/efo/EFO_0005054, http://www.ebi.ac.uk/efo/EFO_0005055 GCST003844 Genome-wide genotyping array 60255 2017-04-01 27659466 van der Harst P 2016-09-27 J Am Coll Cardiol www.ncbi.nlm.nih.gov/pubmed/27659466 52 Genetic Loci Influencing Myocardial Mass. QRS complex (12-leadsum) up to 47,942 European ancestry individuals, up to 690 Orcadian (founder/genetic isolate) individuals 13,263 European ancestry individuals, 3,603 African American individuals, 4,619 Indian ancestry individuals Affymetrix, Illumina, Perlegen [2766983] (imputed) 21 QRS amplitude, QRS complex http://www.ebi.ac.uk/efo/EFO_0007742, http://www.ebi.ac.uk/efo/EFO_0005054 GCST003872 Genome-wide genotyping array 48632 2017-04-01 27659466 van der Harst P 2016-09-27 J Am Coll Cardiol www.ncbi.nlm.nih.gov/pubmed/27659466 52 Genetic Loci Influencing Myocardial Mass. QRS complex (Cornell) up to 58,172 European ancestry individuals, up to 690 Orcadian (founder/genetic isolate) individuals 13,263 European ancestry individuals, 3,603 African American individuals, 4,619 Indian ancestry individuals Affymetrix, Illumina, Perlegen [2766983] (imputed) 17 QRS amplitude, QRS complex http://www.ebi.ac.uk/efo/EFO_0007742, http://www.ebi.ac.uk/efo/EFO_0005054 GCST003871 Genome-wide genotyping array 58862 2017-04-01 27659466 van der Harst P 2016-09-27 J Am Coll Cardiol www.ncbi.nlm.nih.gov/pubmed/27659466 52 Genetic Loci Influencing Myocardial Mass. QRS complex (Sokolow-Lyon) up to 54,303 European ancestry individuals, up to 690 Orcadian (founder/genetic isolate) individuals 13,263 European ancestry individuals, 3,603 African American individuals, 4,619 Indian ancestry individuals Affymetrix, Illumina, Perlegen [2766983] (imputed) 9 QRS amplitude, QRS complex http://www.ebi.ac.uk/efo/EFO_0007742, http://www.ebi.ac.uk/efo/EFO_0005054 GCST003870 Genome-wide genotyping array 54993 2017-02-24 27663945 Middeldorp CM 2016-08-05 J Am Acad Child Adolesc Psychiatry www.ncbi.nlm.nih.gov/pubmed/27663945 A Genome-Wide Association Meta-Analysis of Attention-Deficit/Hyperactivity Disorder Symptoms in Population-Based Pediatric Cohorts. Attention deficit hyperactivity disorder symptom score 17,666 children NA Affymetrix, Illumina [at least 5260671] (imputed) 9 ADHD symptom measurement http://www.ebi.ac.uk/efo/EFO_0007860 GCST003657 Genome-wide genotyping array 17666 2017-03-09 27665939 Liang KH 2016-09-26 Sci Rep www.ncbi.nlm.nih.gov/pubmed/27665939 UGT2B28 genomic variation is associated with hepatitis B e-antigen seroconversion in response to antiviral therapy. Hepatitis B (viral clearance) 27 Asian ancestry delayed seroconversion cases, 30 Asian ancestry spontaneously recovered controls 192 Asian ancestry delayed seroconversion cases, 110 Asian ancestry spontaneously recovered controls Affymetrix [478372] 0 seroconversion, hepatitis B virus infection http://www.ebi.ac.uk/efo/EFO_0007851, http://www.ebi.ac.uk/efo/EFO_0004197 GCST003718 Genome-wide genotyping array 57 2017-06-15 28118524 Saxena R 2017-01-24 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/28118524 A Multinational Arab Genome-Wide Association Study Identifies New Genetic Associations for Rheumatoid Arthritis. Rheumatoid arthritis 97 African admixed Arab ancestry cases, 410 non-African admixed Arab ancestry cases, 4 Arab ancestry cases, 56 African admixed Arab ancestry controls, 290 non-African admixed Arab ancestry controls, 6 Arab ancestry controls 283 Arab ancestry cases, 221 Arab ancestry controls Illumina [7000653] (imputed) 4 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST004172 Genome-wide genotyping array 863 2017-06-15 28118524 Saxena R 2017-01-24 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/28118524 A Multinational Arab Genome-Wide Association Study Identifies New Genetic Associations for Rheumatoid Arthritis. Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive) 357 African admixed and non-African admixed Arab ancestry cases, 352 African admixed and non-African admixed Arab ancestry controls 234 Arab ancestry cases, 225 Arab ancestry controls Illumina [7000653] (imputed) 4 rheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0007837, http://www.ebi.ac.uk/efo/EFO_0007791 GCST004174 Genome-wide genotyping array 709 2017-06-15 28118524 Saxena R 2017-01-24 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/28118524 A Multinational Arab Genome-Wide Association Study Identifies New Genetic Associations for Rheumatoid Arthritis. Rheumatoid arthritis (rheumatoid factor and anti-cyclic citrullinated peptide seronegative) 154 African admixed and non-African admixed Arab ancestry cases, 352 African admixed and non-African admixed Arab ancestry controls 54 Arab ancestry cases, 225 Arab ancestry controls Illumina [7000653] (imputed) 0 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST004173 Genome-wide genotyping array 506 2017-04-21 28002826 D'Adamo CR 2016-12-22 J Nutrigenet Nutrigenomics www.ncbi.nlm.nih.gov/pubmed/28002826 The CAPN2/CAPN8 Locus on Chromosome 1q Is Associated with Variation in Serum Alpha-Carotene Concentrations. Carotenoid levels (cryptoxanthin) 433 Old Order Amish individuals NA Affymetrix [2193082] (imputed) 0 cryptoxanthin measurement http://www.ebi.ac.uk/efo/EFO_0007897 GCST003934 Genome-wide genotyping array 433 2017-04-21 28002826 D'Adamo CR 2016-12-22 J Nutrigenet Nutrigenomics www.ncbi.nlm.nih.gov/pubmed/28002826 The CAPN2/CAPN8 Locus on Chromosome 1q Is Associated with Variation in Serum Alpha-Carotene Concentrations. Carotenoid levels (alpha-carotene) 433 Old Order Amish individuals NA Affymetrix [2193082] (imputed) 3 alpha-carotene measurement http://www.ebi.ac.uk/efo/EFO_0007893 GCST003938 Genome-wide genotyping array 433 2017-04-21 28002826 D'Adamo CR 2016-12-22 J Nutrigenet Nutrigenomics www.ncbi.nlm.nih.gov/pubmed/28002826 The CAPN2/CAPN8 Locus on Chromosome 1q Is Associated with Variation in Serum Alpha-Carotene Concentrations. Vitamin E levels (alpha-tocopherol) 433 Old Order Amish individuals NA Affymetrix [2193082] (imputed) 0 alpha-tocopherol measurement http://www.ebi.ac.uk/efo/EFO_0007898 GCST003935 Genome-wide genotyping array 433 2017-04-21 28002826 D'Adamo CR 2016-12-22 J Nutrigenet Nutrigenomics www.ncbi.nlm.nih.gov/pubmed/28002826 The CAPN2/CAPN8 Locus on Chromosome 1q Is Associated with Variation in Serum Alpha-Carotene Concentrations. Carotenoid levels (beta-carotene) 433 Old Order Amish individuals NA Affymetrix [2193082] (imputed) 0 beta-carotene measurement http://www.ebi.ac.uk/efo/EFO_0007894 GCST003931 Genome-wide genotyping array 433 2017-04-21 28002826 D'Adamo CR 2016-12-22 J Nutrigenet Nutrigenomics www.ncbi.nlm.nih.gov/pubmed/28002826 The CAPN2/CAPN8 Locus on Chromosome 1q Is Associated with Variation in Serum Alpha-Carotene Concentrations. Carotenoid levels (lutein) 433 Old Order Amish individuals NA Affymetrix [2193082] (imputed) 0 lutein measurement http://www.ebi.ac.uk/efo/EFO_0007895 GCST003932 Genome-wide genotyping array 433 2017-04-21 28002826 D'Adamo CR 2016-12-22 J Nutrigenet Nutrigenomics www.ncbi.nlm.nih.gov/pubmed/28002826 The CAPN2/CAPN8 Locus on Chromosome 1q Is Associated with Variation in Serum Alpha-Carotene Concentrations. Carotenoid levels (zeaxanthin) 433 Old Order Amish individuals NA Affymetrix [2193082] (imputed) 0 zeaxanthin measurement http://www.ebi.ac.uk/efo/EFO_0007896 GCST003933 Genome-wide genotyping array 433 2017-04-21 28002826 D'Adamo CR 2016-12-22 J Nutrigenet Nutrigenomics www.ncbi.nlm.nih.gov/pubmed/28002826 The CAPN2/CAPN8 Locus on Chromosome 1q Is Associated with Variation in Serum Alpha-Carotene Concentrations. Vitamin E levels (gamma-tocopherol) 433 Old Order Amish individuals NA Affymetrix [2193082] (imputed) 0 gamma-tocopherol measurement http://www.ebi.ac.uk/efo/EFO_0007899 GCST003936 Genome-wide genotyping array 433 2017-04-21 28002826 D'Adamo CR 2016-12-22 J Nutrigenet Nutrigenomics www.ncbi.nlm.nih.gov/pubmed/28002826 The CAPN2/CAPN8 Locus on Chromosome 1q Is Associated with Variation in Serum Alpha-Carotene Concentrations. Retinol levels 433 Old Order Amish individuals NA Affymetrix [2193082] (imputed) 0 retinol measurement http://www.ebi.ac.uk/efo/EFO_0007900 GCST003937 Genome-wide genotyping array 433 2017-03-29 27632927 Einarsdottir E 2016-09-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/27632927 Genome-wide association analysis reveals variants on chromosome 19 that contribute to childhood risk of chronic otitis media with effusion. Otitis media 803 Finnish ancestry child cases, 2,073 Finnish ancestry controls NA Illumina [319683] 4 Otitis media http://www.ebi.ac.uk/efo/EFO_0004992 GCST003827 Genome-wide genotyping array 2876 2017-03-29 27632927 Einarsdottir E 2016-09-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/27632927 Genome-wide association analysis reveals variants on chromosome 19 that contribute to childhood risk of chronic otitis media with effusion. Otitis media (chronic) 512 Finnish ancestry child cases, 2,073 Finnish ancestry controls 1,466 child cases, 3,394 controls Illumina [319683] 2 Otitis media http://www.ebi.ac.uk/efo/EFO_0004992 GCST003828 Genome-wide genotyping array 2585 2017-03-29 27632927 Einarsdottir E 2016-09-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/27632927 Genome-wide association analysis reveals variants on chromosome 19 that contribute to childhood risk of chronic otitis media with effusion. Otitis media (recurrent) 702 Finnish ancestry child cases, 2,073 Finnish ancestry controls NA Illumina [319683] 4 Otitis media http://www.ebi.ac.uk/efo/EFO_0004992 GCST003829 Genome-wide genotyping array 2775 2018-04-26 26974007 Ellinghaus D 2016-03-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26974007 Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) 8,726 European ancestry ankylosing spondylitis cases, 19,085 European ancestry Crohn’s disease cases, 6,530 European ancestry psoriasis cases, 3,408 European ancestry primary sclerosing cholangitis cases, 14,513 European ancestry ulcerative colitis cases, 34,213 European ancestry controls NA Illumina [130052] 244 ankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis http://www.ebi.ac.uk/efo/EFO_0003898, http://www.ebi.ac.uk/efo/EFO_0000676, http://www.ebi.ac.uk/efo/EFO_0000729, http://www.ebi.ac.uk/efo/EFO_0000384, http://www.ebi.ac.uk/efo/EFO_0004268 GCST005537 Targeted genotyping array [ImmunoChip] 86475 2017-05-11 28017375 van Rooij FJA 2016-12-22 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/28017375 Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. Mean corpuscular hemoglobin concentration up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals. 16,389 European and African American individuals. NR [2500000] (imputed) 20 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST004007 Genome-wide genotyping array 39703 2017-05-11 28017375 van Rooij FJA 2016-12-22 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/28017375 Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. Red blood cell count up to 40,258 European ancestry individuals, up to 16,128 African American individuals, up to 15,252 East Asian individuals. 16,389 individuals of European and African American ancestry. NR [2500000] (imputed) 20 erythrocyte count http://www.ebi.ac.uk/efo/EFO_0004305 GCST004008 Genome-wide genotyping array 71638 2017-05-11 28017375 van Rooij FJA 2016-12-22 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/28017375 Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. Mean corpuscular hemoglobin up to 21,020 European ancestry individuals, up to 3,621 African American individuals, up to 15,062 East Asian individuals. 16,389 individuals of European and African American ancestry. NR [2500000] (imputed) 39 mean corpuscular hemoglobin http://www.ebi.ac.uk/efo/EFO_0004527 GCST004006 Genome-wide genotyping array 39703 2017-05-11 28017375 van Rooij FJA 2016-12-22 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/28017375 Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. Hematocrit up to 40,258 European ancestry individuals, up to 16,128 African American individuals, up to 15,252 East Asian ancestry individuals. 16,389 European and African American individuals NR [2500000] (imputed) 15 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST004003 Genome-wide genotyping array 71638 2017-05-11 28017375 van Rooij FJA 2016-12-22 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/28017375 Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. Mean corpuscular volume up to 29,946 European ancestry individuals, up to 6150 African American individuals, 15,074 East Asian individuals. 16,389 individuals of European and African American ancestry. NR [2500000] (imputed) 58 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST004004 Genome-wide genotyping array 51170 2017-05-11 28017375 van Rooij FJA 2016-12-22 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/28017375 Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. Hemoglobin levels up to 40,258 European ancestry individuals, 16,128 African American individuals, up to 15,252 East Asian ancestry individuals. 16,389 European and African American individuals Affymetrix, Illumina [2500000] (imputed) 14 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST004005 Genome-wide genotyping array 71638 2017-06-12 28282560 Pott J 2017-02-24 Atherosclerosis www.ncbi.nlm.nih.gov/pubmed/28282560 Genome-wide meta-analysis identifies novel loci of plaque burden in carotid artery. Carotid plaque burden 7,189 European ancestry individuals NA Affymetrix [9576485] (imputed) 39 carotid plaque build http://www.ebi.ac.uk/efo/EFO_0006501 GCST004162 Genome-wide genotyping array 7189 2017-06-06 28273873 Park YM 2017-03-05 Nutrients www.ncbi.nlm.nih.gov/pubmed/28273873 Interaction between Single Nucleotide Polymorphism and Urinary Sodium, Potassium, and Sodium-Potassium Ratio on the Risk of Hypertension in Korean Adults. Hypertension 8,839 Korean ancestry individuals. NA Affymetrix [1291657] (imputed) 3 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST004143 Genome-wide genotyping array 8839 2017-07-04 28317342 Hivert MF 2017-03-20 Obesity (Silver Spring) www.ncbi.nlm.nih.gov/pubmed/28317342 Genetic determinants of adiponectin regulation revealed by pregnancy. Adiponectin levels in pregnancy 1,322 European ancestry individuals 522 European ancestry individuals, 174 French Canadian founder individuals Illumina [NR] 3 adiponectin measurement http://www.ebi.ac.uk/efo/EFO_0004502 GCST004289 Genome-wide genotyping array 1322 2017-06-29 28348047 Li C 2017-04-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/28348047 Genome-Wide Association Study Meta-Analysis of Long-Term Average Blood Pressure in East Asians. Systolic blood pressure (long-term average) 18,422 East Asian ancestry individuals up to 46,629 European ancestry individuals Affymetrix, Illumina [up to 2400000] (imputed) 4 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST004257 Genome-wide genotyping array 18422 2017-06-29 28348047 Li C 2017-04-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/28348047 Genome-Wide Association Study Meta-Analysis of Long-Term Average Blood Pressure in East Asians. Diastolic blood pressure (long-term average) 18,422 East Asian ancestry individuals up to 46,629 European ancestry individuals Affymetrix, Illumina [up to 2400000] (imputed) 3 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST004258 Genome-wide genotyping array 18422 2017-06-29 28348047 Li C 2017-04-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/28348047 Genome-Wide Association Study Meta-Analysis of Long-Term Average Blood Pressure in East Asians. Pulse pressure (long-term average) 18,422 East Asian ancestry individuals up to 46,629 European ancestry individuals Affymetrix, Illumina [up to 2400000] (imputed) 0 pulse pressure measurement http://www.ebi.ac.uk/efo/EFO_0005763 GCST004260 Genome-wide genotyping array 18422 2017-06-29 28348047 Li C 2017-04-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/28348047 Genome-Wide Association Study Meta-Analysis of Long-Term Average Blood Pressure in East Asians. Mean arterial pressure (long-term average) 18,422 East Asian ancestry individuals up to 46,629 European ancestry individuals Affymetrix, Illumina [up to 2400000] (imputed) 4 mean arterial pressure http://www.ebi.ac.uk/efo/EFO_0006340 GCST004259 Genome-wide genotyping array 18422 2017-07-13 28416812 Yang L 2017-04-18 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/28416812 A new locus regulating MICALL2 expression was identified for association with executive inhibition in children with attention deficit hyperactivity disorder. Executive inhibition (Stroop WIT and CIT) in attention deficit hyperactivity disorder up to 780 Han Chinese ancestry child or adolescent individuals up to 922 Han Chinese ancestry child or adolescent individuals Affymetrix [at least 644166] (imputed) 1 cognitive inhibition measurement http://www.ebi.ac.uk/efo/EFO_0007969 GCST004336 Genome-wide genotyping array 780 2017-06-08 28166215 Hobbs BD 2017-02-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28166215 Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. Chronic obstructive pulmonary disease 11,157 European ancestry cases, 36,699 European ancestry controls, 1,142 African American cases, 2,380 African American controls, 199 Korean ancestry cases, 6,741 Korean ancestry controls, 52 Hispanic cases, 548 Hispanic controls. 12,051 European ancestry cases, 11,111 European ancestry controls, 153 Korean ancestry cases, 205 Korean ancestry controls. Affymetrix, Illumina [NR] (imputed) 31 chronic obstructive pulmonary disease http://www.ebi.ac.uk/efo/EFO_0000341 GCST004147 Genome-wide genotyping array 58918 2017-05-24 28093568 Trampush JW 2017-01-17 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/28093568 GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium. Cognitive function up to 35,298 European ancestry individuals NA Affymetrix, Illumina [8037763] (imputed) 13 intelligence http://www.ebi.ac.uk/efo/EFO_0004337 GCST004077 Genome-wide genotyping array 35298 2017-06-21 28270201 Nagy R 2017-03-07 Genome Med www.ncbi.nlm.nih.gov/pubmed/28270201 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants. Diastolic blood pressure 19,546 British ancestry individuals from 6863 families. NA Illumina [24111857] (imputed) 4 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST004203 Genome-wide genotyping array 26409 2017-06-21 28270201 Nagy R 2017-03-07 Genome Med www.ncbi.nlm.nih.gov/pubmed/28270201 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants. Systolic blood pressure 19,547 British ancestry individuals from 6863 families. NA Illumina [24111857] (imputed) 0 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST004204 Genome-wide genotyping array 26410 2017-06-21 28270201 Nagy R 2017-03-07 Genome Med www.ncbi.nlm.nih.gov/pubmed/28270201 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants. Pulse pressure 19,546 British ancestry individuals from 6863 families. NA Illumina [24111857] (imputed) 0 pulse pressure measurement http://www.ebi.ac.uk/efo/EFO_0005763 GCST004205 Genome-wide genotyping array 26409 2017-06-21 28270201 Nagy R 2017-03-07 Genome Med www.ncbi.nlm.nih.gov/pubmed/28270201 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants. Fasting plasma glucose 15,226 British ancestry non-diabetics individuals from 6863 families, 948 British ancestry diabetic individuals from 6863 families. NA Illumina [24111857] (imputed) 16 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST004206 Genome-wide genotyping array 29900 2017-06-21 28270201 Nagy R 2017-03-07 Genome Med www.ncbi.nlm.nih.gov/pubmed/28270201 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants. HDL cholesterol 19,223 British ancestry individuals from 6863 families. NA Illumina [24111857] (imputed) 26 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST004207 Genome-wide genotyping array 26086 2017-06-21 28270201 Nagy R 2017-03-07 Genome Med www.ncbi.nlm.nih.gov/pubmed/28270201 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants. Body mass index 19,900 British ancestry individuals from 6863 families. NA Illumina [24111857] (imputed) 5 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST004208 Genome-wide genotyping array 26763 2017-06-21 28270201 Nagy R 2017-03-07 Genome Med www.ncbi.nlm.nih.gov/pubmed/28270201 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants. Cholesterol, total 19,259 British ancestry individuals from 6863 families. NA Illumina [24111857] (imputed) 17 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST004209 Genome-wide genotyping array 26122 2017-06-21 28270201 Nagy R 2017-03-07 Genome Med www.ncbi.nlm.nih.gov/pubmed/28270201 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants. Body fat percentage 19,480 British ancestry individuals from 6863 families. NA Illumina [24111857] (imputed) 6 body fat percentage http://www.ebi.ac.uk/efo/EFO_0007800 GCST004210 Genome-wide genotyping array 26343 2017-06-21 28270201 Nagy R 2017-03-07 Genome Med www.ncbi.nlm.nih.gov/pubmed/28270201 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants. Urate levels 2077 British ancestry individuals from 6863 families. NA Illumina [24111857] (imputed) 4 urate measurement http://www.ebi.ac.uk/efo/EFO_0004531 GCST004211 Genome-wide genotyping array 8940 2017-06-21 28270201 Nagy R 2017-03-07 Genome Med www.ncbi.nlm.nih.gov/pubmed/28270201 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants. Height 19,965 British ancestry individuals from 6863 families. NA Illumina [24111857] (imputed) 32 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST004212 Genome-wide genotyping array 26828 2017-06-21 28270201 Nagy R 2017-03-07 Genome Med www.ncbi.nlm.nih.gov/pubmed/28270201 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants. Resting heart rate 19,920 British ancestry individuals from 6863 families. NA Illumina [24111857] (imputed) 6 resting heart rate http://www.ebi.ac.uk/efo/EFO_0004351 GCST004213 Genome-wide genotyping array 26783 2017-06-21 28270201 Nagy R 2017-03-07 Genome Med www.ncbi.nlm.nih.gov/pubmed/28270201 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants. Creatinine levels 16,347 British ancestry from 6863 families. NA Illumina [24111857] (imputed) 4 creatinine measurement http://www.ebi.ac.uk/efo/EFO_0004518 GCST004214 Genome-wide genotyping array 23210 2017-06-21 28270201 Nagy R 2017-03-07 Genome Med www.ncbi.nlm.nih.gov/pubmed/28270201 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants. Urea levels 19,293 British ancestry individuals from 6863 families. NA Illumina [24111857] (imputed) 5 blood urea nitrogen measurement http://www.ebi.ac.uk/efo/EFO_0004741 GCST004215 Genome-wide genotyping array 26156 2017-06-21 28270201 Nagy R 2017-03-07 Genome Med www.ncbi.nlm.nih.gov/pubmed/28270201 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants. Waist-to-hip ratio adjusted for body mass index 19,695 British ancestry individuals from 6863 families. NA Illumina [24111857] (imputed) 4 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST004216 Genome-wide genotyping array 26558 2017-05-15 27790247 He L 2016-11-03 Front Genet www.ncbi.nlm.nih.gov/pubmed/27790247 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases. Age-related diseases and mortality 9,618 European ancestry individuals 19,796 European ancestry individuals Affymetrix [NR] 14 cancer, heart failure, diabetes mellitus, stroke, atrial fibrillation, mortality, coronary artery disease http://www.ebi.ac.uk/efo/EFO_0000311, http://www.ebi.ac.uk/efo/EFO_0003144, http://www.ebi.ac.uk/efo/EFO_0000400, http://www.ebi.ac.uk/efo/EFO_0000712, http://www.ebi.ac.uk/efo/EFO_0000275, http://www.ebi.ac.uk/efo/EFO_0004352, http://www.ebi.ac.uk/efo/EFO_0001645 GCST004044 Genome-wide genotyping array 9618 2017-05-15 27790247 He L 2016-11-03 Front Genet www.ncbi.nlm.nih.gov/pubmed/27790247 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases. Age-related diseases, mortality and associated endophenotypes 9,618 European ancestry individuals 19,796 European ancestry individuals Affymetrix [NR] 44 total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, cancer, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0000712, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0000275, http://www.ebi.ac.uk/efo/EFO_0004612, http://www.ebi.ac.uk/efo/EFO_0001645, http://www.ebi.ac.uk/efo/EFO_0000311, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0003144, http://www.ebi.ac.uk/efo/EFO_0000400, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004352 GCST004045 Genome-wide genotyping array 9618 2017-05-15 27790247 He L 2016-11-03 Front Genet www.ncbi.nlm.nih.gov/pubmed/27790247 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases. Age-related disease endophenotypes 9,618 European ancestry individuals 19,796 European ancestry individuals Affymetrix [NR] 31 total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0007928, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612 GCST004046 Genome-wide genotyping array 9618 2016-11-28 26921259 Baurley JW 2016-02-27 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/26921259 Smokescreen: a targeted genotyping array for addiction research. Nicotine metabolite ratio 49 African American ancestry individuals, 51 Asian American ancestry individuals, 215 European American individuals NA Affymetrix [646247] 1 nicotine metabolite ratio http://www.ebi.ac.uk/efo/EFO_0007794 GCST003376 Genome-wide genotyping array 315 2017-06-26 28334899 Spracklen CN 2017-02-21 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28334899 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. Total cholesterol levels 22,814 East Asian ancestry individuals 57,490 East Asian ancestry individuals Affymetrix, Illumina [~ 2400000] (imputed) 16 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST004231 Genome-wide genotyping array 22814 2017-06-26 28334899 Spracklen CN 2017-02-21 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28334899 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. LDL cholesterol levels 32,285 East Asian ancestry individuals, 173,082 European ancestry individuals 8,478 Chinese ancestry individuals Affymetrix, Illumina [~ 1900000] (imputed) 66 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST004233 Genome-wide genotyping array 205367 2017-06-26 28334899 Spracklen CN 2017-02-21 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28334899 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. HDL cholesterol levels 25,169 East Asian ancestry individuals 45,953 East Asian ancestry individuals Affymetrix, Illumina [~ 2400000] (imputed) 18 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST004234 Genome-wide genotyping array 25169 2017-06-26 28334899 Spracklen CN 2017-02-21 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28334899 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. Total cholesterol levels 32,576 East Asian ancestry individuals, 187,365 European ancestry individuals 10,855 Chinese ancestry individuals Affymetrix, Illumina [up to 1900000] (imputed) 81 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST004235 Genome-wide genotyping array 219941 2017-06-26 28334899 Spracklen CN 2017-02-21 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28334899 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. LDL cholesterol levels 22,526 East Asian ancestry individuals 37,842 East Asian ancestry individuals Affymetrix, Illumina [~ 2400000] (imputed) 13 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST004236 Genome-wide genotyping array 22526 2017-06-26 28334899 Spracklen CN 2017-02-21 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28334899 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. Triglyceride levels 28,183 East Asian ancestry individuals, 177,861 European ancestry individuals 10,857 Chinese ancestry individuals Affymetrix, Illumina [up to 1900000] (imputed) 49 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST004237 Genome-wide genotyping array 206044 2017-06-26 28334899 Spracklen CN 2017-02-21 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28334899 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. Triglyceride levels 18,421 East Asian ancestry individuals 38,060 East Asian ancestry individuals Affymetrix, Illumina [~ 2400000] (imputed) 11 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST004238 Genome-wide genotyping array 18421 2017-06-26 28334899 Spracklen CN 2017-02-21 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28334899 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. HDL cholesterol levels 34,930 East Asian ancestry individuals, 187,167 European ancestry individuals 8,741 Chinese ancestry individuals Affymetrix, Illumina [~ 1900000] (imputed) 90 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST004232 Genome-wide genotyping array 222097 2017-06-26 28179588 Fagerholm R 2017-03-14 Oncotarget www.ncbi.nlm.nih.gov/pubmed/28179588 TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer. Survival in breast cancer (TP53 expression interaction) 572 Finnish ancestry cases 4,610 European ancestry cases NR [NR] 0 overall survival, breast carcinoma, TP53 mutation status http://www.ebi.ac.uk/efo/EFO_0000638, http://www.ebi.ac.uk/efo/EFO_0000305, http://www.ebi.ac.uk/efo/EFO_0008382 GCST004229 Genome-wide genotyping array 572 2017-06-26 28179588 Fagerholm R 2017-03-14 Oncotarget www.ncbi.nlm.nih.gov/pubmed/28179588 TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer. Survival in TP53 positive breast cancer 157 Finnish ancestry cases NA NR [NR] 0 overall survival, TP53 Positive Breast Carcinoma http://www.ebi.ac.uk/efo/EFO_0000638, http://www.ebi.ac.uk/efo/EFO_1002010 GCST004228 Genome-wide genotyping array 157 2017-05-11 28029757 Merkel PA 2016-12-28 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/28029757 Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis. Vasculitis associated with antineutrophil cytoplasmic antibody reactive to myeloperoxidase 324 European ancestry cases and 3258 European ancestry controls. 54 European ancestry cases and 1465 European ancestry controls. Affymetrix [at least 333035] (imputed) 1 anti-neutrophil antibody associated vasculitis http://www.ebi.ac.uk/efo/EFO_0004826 GCST003977 Genome-wide genotyping array 3582 2017-05-11 28029757 Merkel PA 2016-12-28 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/28029757 Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis. Vasculitis associated with antineutrophil cytoplasmic antibody reactive to proteinase-3 882 European ancestry cases and 3258 European ancestry controls. 479 European ancestry cases and 1465 European ancestry controls. Affymetrix [at least 333035] (imputed) 0 anti-neutrophil antibody associated vasculitis http://www.ebi.ac.uk/efo/EFO_0004826 GCST003978 Genome-wide genotyping array 4140 2017-05-11 28029757 Merkel PA 2016-12-28 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/28029757 Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis. Antineutrophil cytoplasmic antibody-associated vasculitis 1,015 European ancestry granulomatosis with polyangiitis cases, 206 European ancestry microscopic polyangiitis cases, 3,258 European ancestry controls. 541 European ancestry granulomatosis with polyangiitis cases, 30 European ancestry microscopic polyangiitis cases, 1,465 European ancestry controls. Affymetrix [at least 333035] (imputed) 6 anti-neutrophil antibody associated vasculitis http://www.ebi.ac.uk/efo/EFO_0004826 GCST003976 Genome-wide genotyping array 4479 2017-03-30 27529621 Otowa T 2016-08-16 PLoS One www.ncbi.nlm.nih.gov/pubmed/27529621 The First Pilot Genome-Wide Gene-Environment Study of Depression in the Japanese Population. Depressive symptoms 320 Japanese ancestry individuals 439 Japanese ancestry individuals Affymetrix [534848] 1 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST003836 Genome-wide genotyping array 320 2017-03-30 27529621 Otowa T 2016-08-16 PLoS One www.ncbi.nlm.nih.gov/pubmed/27529621 The First Pilot Genome-Wide Gene-Environment Study of Depression in the Japanese Population. Depressive symptoms (stressful life events interaction) 320 Japanese ancestry individuals 439 Japanese ancestry individuals Affymetrix [534848] 4 depressive symptom measurement, stressful life event measurement http://www.ebi.ac.uk/efo/EFO_0007006, http://www.ebi.ac.uk/efo/EFO_0007781 GCST003835 Genome-wide genotyping array 320 2017-07-01 28135244 Warren HR 2017-01-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28135244 Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Diastolic blood pressure 140,886 European ancestry individuals 190,318 European ancestry individuals Affymetrix [~ 9800000] (imputed) 94 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST004280 Genome-wide genotyping array 140886 2017-07-01 28135244 Warren HR 2017-01-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28135244 Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Pulse pressure 140,886 European ancestry individuals 190,318 European ancestry individuals Affymetrix [~ 9800000] (imputed) 94 pulse pressure measurement http://www.ebi.ac.uk/efo/EFO_0005763 GCST004278 Genome-wide genotyping array 140886 2017-07-01 28135244 Warren HR 2017-01-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28135244 Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Systolic blood pressure 140,882 European ancestry individuals 190,318 European ancestry individuals Affymetrix [~ 9800000] (imputed) 42 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST004279 Genome-wide genotyping array 140882 2017-05-12 28039329 Noordam R 2016-12-30 J Med Genet www.ncbi.nlm.nih.gov/pubmed/28039329 A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. QT interval (tricyclic/tetracyclic antidepressant use interaction) 1,250 European ancestry users, 295 African American users, 1,886 Hispanic or Latino ancestry users, 40,701 European ancestry non-users, 9,940 African American non-users, 67,863 Hispanic or Latino ancestry non-users NA Affymetrix, Illumina [NR] (imputed) 1 response to tetracyclic antidepressant, QT interval, response to tricyclic antidepressant http://www.ebi.ac.uk/efo/EFO_0007917, http://www.ebi.ac.uk/efo/EFO_0004682, http://www.ebi.ac.uk/efo/EFO_0007916 GCST004010 Genome-wide genotyping array 121935 2017-05-12 28039329 Noordam R 2016-12-30 J Med Genet www.ncbi.nlm.nih.gov/pubmed/28039329 A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. RR interval (tricyclic/tetracyclic antidepressant use interaction) 1,417 European ancestry users, 295 African American users, 174 Hispanic or Latino ancestry users, 44,289 European ancestry non-users, 9,940 African American non-users, 13,634 Hispanic or Latino ancestry non-users NA Affymetrix, Illumina [NR] (imputed) 3 RR interval, response to tetracyclic antidepressant, response to tricyclic antidepressant http://www.ebi.ac.uk/efo/EFO_0004831, http://www.ebi.ac.uk/efo/EFO_0007917, http://www.ebi.ac.uk/efo/EFO_0007916 GCST004011 Genome-wide genotyping array 69749 2017-06-30 28289848 Haralambieva IH 2017-04-01 Hum Genet www.ncbi.nlm.nih.gov/pubmed/28289848 Genome-wide associations of CD46 and IFI44L genetic variants with neutralizing antibody response to measles vaccine. Immune response to measles vaccine (measles-specific neutralising antibody titre) 2,555 European ancestry individuals, 317 African American individuals NA Illumina [at least 508199] 6 response to vaccine http://www.ebi.ac.uk/efo/EFO_0004645 GCST004269 Genome-wide genotyping array 2872 2017-06-30 28289848 Haralambieva IH 2017-04-01 Hum Genet www.ncbi.nlm.nih.gov/pubmed/28289848 Genome-wide associations of CD46 and IFI44L genetic variants with neutralizing antibody response to measles vaccine. Immune response to measles vaccine (measles-induced IFN gamma) up to 2,555 European ancestry individuals, up to 317 African American individuals NA Illumina [at least 508199] 1 response to vaccine http://www.ebi.ac.uk/efo/EFO_0004645 GCST004268 Genome-wide genotyping array 2872 2017-05-19 28054174 Leslie EJ 2017-01-04 Hum Genet www.ncbi.nlm.nih.gov/pubmed/28054174 Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate. Cleft palate 272 Asian ancestry case-parent trios, 161 Asian ancestry controls, 38 European ancestry cases, 296 European ancestry case-parent trios, 835 European ancestry controls, 40 Latino or African cases, 34 Latino or African case-parent trios, 704 Latino or African controls, 14 case-parent trios. NA Illumina [6090031] (imputed) 7 Cleft palate http://purl.obolibrary.org/obo/HP_0000175 GCST004052 Genome-wide genotyping array 2394 2017-05-19 28054174 Leslie EJ 2017-01-04 Hum Genet www.ncbi.nlm.nih.gov/pubmed/28054174 Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate. Orofacial clefts 83 Asian ancestry cases, 1,445 Asian ancestry case-parent trios, 161 Asian ancestry controls, 208 European ancestry cases, 1,284 European ancestry case-parent trios, 835 European ancestry controls, 610 Latino or African cases, 663 Latino or African case-parent trios, 704 Latino or African controls, 35 case-parent trios. NA Illumina [6090031] (imputed) 24 Oral cleft http://purl.obolibrary.org/obo/HP_0000202 GCST004051 Genome-wide genotyping array 6028 2017-05-19 28054174 Leslie EJ 2017-01-04 Hum Genet www.ncbi.nlm.nih.gov/pubmed/28054174 Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate. Cleft lip with or without cleft palate 83 Asian ancestry cases, 1,173 Asian ancestry case-parent trios, 161 Asian ancestry controls,170 European ancestry cases, 988 European ancestry case-parent trios, 835 European ancestry controls, 570 Latino or African cases, 629 Latino or African case-parent trios, 704 Latino or African controls, 21 case-parent trios. NA Illumina [6090031] (imputed) 32 Cleft palate, cleft lip http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959 GCST004050 Genome-wide genotyping array 5334 2017-06-29 28388302 Petros Z 2017-04-01 OMICS www.ncbi.nlm.nih.gov/pubmed/28388302 Genome-Wide Association and Replication Study of Hepatotoxicity Induced by Antiretrovirals Alone or with Concomitant Anti-Tuberculosis Drugs. Liver injury in anti-retroviral drug treated HIV 14 Ethiopian cases with HIV, 293 Ethiopian controls with HIV. 7 Ethiopian cases with HIV, 66 Ethiopian controls with HIV. Illumina [662282] 1 response to efavirenz, drug-induced liver injury http://www.ebi.ac.uk/efo/EFO_0006904, http://www.ebi.ac.uk/efo/EFO_0004228 GCST004261 Genome-wide genotyping array 307 2017-06-29 28388302 Petros Z 2017-04-01 OMICS www.ncbi.nlm.nih.gov/pubmed/28388302 Genome-Wide Association and Replication Study of Hepatotoxicity Induced by Antiretrovirals Alone or with Concomitant Anti-Tuberculosis Drugs. Liver injury in combined anti-retroviral and anti-tuberculosis drug-treated HIV with tuberculosis 27 Ethiopian cases with HIV and tuberculosis, 159 Ethiopian controls with HIV and tuberculosis. 8 Ethiopian cases with HIV and tuberculosis, up to 108 Ethiopian controls with HIV and tuberculosis. Illumina [662807] 3 response to rifampicin, response to efavirenz, drug-induced liver injury http://www.ebi.ac.uk/efo/EFO_0007866, http://www.ebi.ac.uk/efo/EFO_0006904, http://www.ebi.ac.uk/efo/EFO_0004228 GCST004262 Genome-wide genotyping array 186 2017-07-21 28416822 Low SK 2017-04-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28416822 Identification of six new genetic loci associated with atrial fibrillation in the Japanese population. Atrial fibrillation 8,180 Japanese ancestry cases, 28,612 Japanese ancestry controls 3,120 Japanese ancestry cases, 125,064 Japanese ancestry controls, 15,993 European ancestry cases, 113,719 European ancestry controls Illumina [5018049] (imputed) 19 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST004373 Genome-wide genotyping array 36792 2017-06-27 28352666 Liu TC 2017-03-23 JCI Insight www.ncbi.nlm.nih.gov/pubmed/28352666 LRRK2 but not ATG16L1 is associated with Paneth cell defect in Japanese Crohn's disease patients. Paneth cell defects in Crohn's disease 98 Japanese ancestry cases NA Affymetrix [4198245] (imputed) 9 abnormal paneth cell measurement http://www.ebi.ac.uk/efo/EFO_0007963 GCST004251 Genome-wide genotyping array 98 2016-12-13 26915486 Adams JN 2016-02-23 Gene www.ncbi.nlm.nih.gov/pubmed/26915486 Genetic analysis of advanced glycation end products in the DHS MIND study. Advanced glycation end-product levels 399 diabetes cases, 107 non-diabetes controls from 240 families NA Affymetrix [371951] 5 advanced glycation end-product measurement, type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0007819, http://www.ebi.ac.uk/efo/EFO_0001360 GCST003457 Genome-wide genotyping array 746 2017-03-22 27669169 Chang IS 2016-09-26 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/27669169 Genetic Modifiers of Progression-Free Survival in Never-Smoking Lung Adenocarcinoma Patients Treated with First-Line Tyrosine Kinase Inhibitors. Progression free survival in EGFR-mutation-positive never-smoking lung adenocarcinoma treated with gefitinib or erlotinib 128 Chinese ancestry cases 153 cases, 70 Chinese ancestry cases Illumina [418580] 0 progression free survival, response to gefitinib, response to erlotinib, lung adenocarcinoma http://www.ebi.ac.uk/efo/EFO_0004920, http://www.ebi.ac.uk/efo/EFO_0007867, http://www.ebi.ac.uk/efo/EFO_0007868, http://www.ebi.ac.uk/efo/EFO_0000571 GCST003794 Genome-wide genotyping array 128 2017-03-16 27669027 Boueiz A 2016-09-26 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/27669027 Genome-Wide Association Study of the Genetic Determinants of Emphysema Distribution. Emphysema distribution in smoking 7,039 European ancestry individuals, 2,955 African American individuals, 1538 individuals NA Illumina [at least 10657975] (imputed) 9 emphysema pattern measurement http://www.ebi.ac.uk/efo/EFO_0005850 GCST003761 Genome-wide genotyping array 11532 2017-06-16 28166213 Wain LV 2017-02-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28166213 Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. Lung function (FEV1) 48,943 European ancestry individuals. 57,176 European ancestry individuals, 38,199 individuals. Affymetrix [up to 27624732] (imputed) 33 forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0004314 GCST004183 Genome-wide genotyping array 48943 2017-06-16 28166213 Wain LV 2017-02-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28166213 Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. Lung function (FVC) 48,943 European ancestry individuals. 57,176 European ancestry individuals, 38,199 individuals. Affymetrix [27624732] (imputed) 20 vital capacity http://www.ebi.ac.uk/efo/EFO_0004312 GCST004184 Genome-wide genotyping array 48943 2017-06-16 28166213 Wain LV 2017-02-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28166213 Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. Lung function (FEV1/FVC) 48,943 European ancestry individuals 57,176 European ancestry individuals, 38,199 individuals. Affymetrix [27624732] (imputed) 56 FEV/FEC ratio http://www.ebi.ac.uk/efo/EFO_0004713 GCST004185 Genome-wide genotyping array 48943 2017-06-08 28165464 Law PJ 2017-02-06 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28165464 Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia. Chronic lymphocytic leukemia 4,478 European ancestry cases and 13,213 European ancestry controls. 1,722 European ancestry cases and 4,385 European ancestry controls. Affymetrix, Illumina [> 10000000] (imputed) 37 chronic lymphocytic leukemia http://www.ebi.ac.uk/efo/EFO_0000095 GCST004146 Genome-wide genotyping array 17691 2017-06-02 28073927 Springelkamp H 2017-01-10 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28073927 New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics. Optic cup area 20,353 European ancestry individuals, 2,131 Erasmus Rucphen (founder/genetic isolate) individuals 7,333 Asian ancestry individuals Affymetrix, Illumina [~ 8000000] (imputed) 47 optic cup area measurement http://www.ebi.ac.uk/efo/EFO_0006940 GCST004137 Genome-wide genotyping array 22484 2017-05-24 28073927 Springelkamp H 2017-01-10 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28073927 New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics. Vertical cup-disc ratio 21,768 European ancestry individuals, 2,131 Erasmus Rucphen (founder/genetic isolate) individuals 8,168 Asian ancestry individuals Affymetrix, Illumina [~ 8000000] (imputed) 46 cup-to-disc ratio measurement http://www.ebi.ac.uk/efo/EFO_0006939 GCST004075 Genome-wide genotyping array 23899 2017-05-24 28073927 Springelkamp H 2017-01-10 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28073927 New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics. Optic disc area 20,373 European ancestry individuals, 2,131 Erasmus Rucphen (founder/genetic isolate) individuals 7,302 Asian ancestry individuals Affymetrix, Illumina [~ 8000000] (imputed) 32 optic disc area measurement http://www.ebi.ac.uk/efo/EFO_0006937 GCST004076 Genome-wide genotyping array 22504 2017-05-24 28073927 Springelkamp H 2017-01-10 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28073927 New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics. Intraocular pressure 25,916 European ancestry individuals, 1,073 Orcadian (founder/genetic isolate) individuals, 2,589 Erasmus Rucphen (founder/genetic isolate) individuals 8,352 Asian ancestry individuals Affymetrix, Illumina [~ 8000000] (imputed) 17 intraocular pressure measurement http://www.ebi.ac.uk/efo/EFO_0004695 GCST004074 Genome-wide genotyping array 29578 2017-06-12 28222112 Dumitrescu L 2017-01-01 PLoS One www.ncbi.nlm.nih.gov/pubmed/28222112 Genome-wide study of resistant hypertension identified from electronic health records. Resistance to antihypertensive treatment in hypertension 1,719 European ancestry resistant cases, 708 European ancestry controlled hypertensives, 1,111 African American, Hispanic and other ancestry resistant cases, 168 African American, Hispanic and other ancestry controlled hypertensives NA Affymetrix, Illumina [2530150] (imputed) 6 treatment-resistant hypertension http://www.ebi.ac.uk/efo/EFO_1002006 GCST004163 Genome-wide genotyping array 3706 2017-06-05 28224759 Pei YF 2017-02-22 Obesity (Silver Spring) www.ncbi.nlm.nih.gov/pubmed/28224759 Genomic variants at 20p11 associated with body fat mass in the European population. Body fat mass 9,179 European ancestry individuals NA Affymetrix [6817908] (imputed) 3 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST004141 Genome-wide genotyping array 9179 2017-06-22 28300201 Hernandez-Pacheco N 2017-03-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28300201 Identification of a novel locus associated with skin colour in African-admixed populations. Skin pigmentation 285 Puerto Rican individuals 373 African American individuals Affymetrix [14000000] (imputed) 42 skin pigmentation http://www.ebi.ac.uk/efo/EFO_0003784 GCST004219 Genome-wide genotyping array 285 2017-01-09 27126917 Spada J 2016-04-29 J Sleep Res www.ncbi.nlm.nih.gov/pubmed/27126917 Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study. Daytime sleep phenotypes 874 European ancestry individuals NA Affymetrix [7141204] (imputed) 101 daytime rest measurement http://www.ebi.ac.uk/efo/EFO_0007828 GCST003518 Genome-wide genotyping array 874 2017-01-16 27126917 Spada J 2016-04-29 J Sleep Res www.ncbi.nlm.nih.gov/pubmed/27126917 Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study. Night sleep phenotypes 941 European ancestry individuals NA Affymetrix [7141204] (imputed) 210 sleep duration, nighttime rest measurement, sleep quality, sleep latency http://www.ebi.ac.uk/efo/EFO_0005271, http://www.ebi.ac.uk/efo/EFO_0007827, http://www.ebi.ac.uk/efo/EFO_0005272, http://www.ebi.ac.uk/efo/EFO_0005280 GCST003542 Genome-wide genotyping array 941 2017-06-02 28115739 Smith AH 2017-01-24 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/28115739 Genome-wide association study of therapeutic opioid dosing identifies a novel locus upstream of OPRM1. Methadone dose in opioid dependence 1,027 European American cases, 383 African American cases NA Illumina [at least 988306] (imputed) 37 methadone dose measurement http://www.ebi.ac.uk/efo/EFO_0007907 GCST004136 Genome-wide genotyping array 1410 2017-08-03 26853712 Zhang YB 2016-02-08 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26853712 Genome-wide association study identifies multiple susceptibility loci for craniofacial microsomia. Craniofacial microsomia 330 Chinese ancestry left-side-affected cases, 609 Chinese ancestry right-side-affected cases, 2,012 Chinese ancestry controls 151 Chinese ancestry left-side-affected cases, 292 Chinese ancestry right-side-affected cases, 1,669 Chinese ancestry controls Illumina [792342] 13 Hemifacial microsomia http://www.orpha.net/ORDO/Orphanet_141136 GCST004412 Genome-wide genotyping array 2951 2018-01-12 29151059 Delgado DA 2017-11-18 J Med Genet www.ncbi.nlm.nih.gov/pubmed/29151059 Genome-wide association study of telomere length among South Asians identifies a second RTEL1 association signal. Telomere length 5,075 Bangladeshi ancestry individuals NA Illumina [~ 6300000] (imputed) 7 telomere length http://www.ebi.ac.uk/efo/EFO_0004505 GCST005143 Genome-wide genotyping array 5075 2017-07-17 28429243 Dudenkov TM 2017-04-20 Breast Cancer Res Treat www.ncbi.nlm.nih.gov/pubmed/28429243 SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway. Estrone conjugates/estrone ratio in resected early stage estrogen-receptor positive breast cancer 707 European ancestry postmenopausal cases, 52 African ancestry postmenopausal cases, 15 Asian ancestry postmenopausal cases NA Illumina [8203257] (imputed) 1 estrone conjugate measurement, estrone measurement http://www.ebi.ac.uk/efo/EFO_0007971, http://www.ebi.ac.uk/efo/EFO_0007970 GCST004360 Genome-wide genotyping array 774 2017-07-17 28429243 Dudenkov TM 2017-04-20 Breast Cancer Res Treat www.ncbi.nlm.nih.gov/pubmed/28429243 SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway. Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer 707 European ancestry postmenopausal cases, 52 African ancestry postmenopausal cases, 15 Asian ancestry postmenopausal cases NA Illumina [8203257] (imputed) 14 androstenedione measurement, estrone measurement http://www.ebi.ac.uk/efo/EFO_0007972, http://www.ebi.ac.uk/efo/EFO_0007970 GCST004361 Genome-wide genotyping array 774 2017-07-17 28429243 Dudenkov TM 2017-04-20 Breast Cancer Res Treat www.ncbi.nlm.nih.gov/pubmed/28429243 SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway. Plasma estrone levels in resected estrogen-receptor positive breast cancer 707 European ancestry postmenopausal cases, 52 African ancestry postmenopausal cases, 15 Asian ancestry postmenopausal cases NA Illumina [8203257] (imputed) 2 estrone measurement http://www.ebi.ac.uk/efo/EFO_0007970 GCST004362 Genome-wide genotyping array 774 2017-07-17 28429243 Dudenkov TM 2017-04-20 Breast Cancer Res Treat www.ncbi.nlm.nih.gov/pubmed/28429243 SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway. Plasma androstenedione levels in resected early stage-receptor positive breast cancer 707 European ancestry postmenopausal cases, 52 African ancestry postmenopausal cases, 15 Asian ancestry postmenopausal cases NA Illumina [8203257] (imputed) 5 androstenedione measurement http://www.ebi.ac.uk/efo/EFO_0007972 GCST004363 Genome-wide genotyping array 774 2017-07-17 28429243 Dudenkov TM 2017-04-20 Breast Cancer Res Treat www.ncbi.nlm.nih.gov/pubmed/28429243 SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway. Plasma estrone conjugates levels in resected early stage estrogen-receptor positive breast cancer 707 European ancestry postmenopausal cases, 52 African ancestry postmenopausal cases, 15 Asian ancestry postmenopausal cases NA Illumina [8203257] (imputed) 2 estrone conjugate measurement http://www.ebi.ac.uk/efo/EFO_0007971 GCST004359 Genome-wide genotyping array 774 2017-07-10 28449029 Munz M 2017-04-25 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28449029 A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis. Aggressive periodontitis 851 European ancestry cases, 6,836 European ancestry controls 223 cases, up to 564 controls Illumina [at least 5870152] (imputed) 5 aggressive periodontitis http://www.ebi.ac.uk/efo/EFO_0006342 GCST004303 Genome-wide genotyping array 7687 2017-07-11 28406950 Kim J 2017-04-13 PLoS One www.ncbi.nlm.nih.gov/pubmed/28406950 Interaction of iron status with single nucleotide polymorphisms on incidence of type 2 diabetes. Prevalent type 2 diabetes 911 Korean ancestry prevalent diabetes cases, 7,024 Korean ancestry incident diabetes and non-diabetes controls NA Affymetrix [352228] 1 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST004304 Genome-wide genotyping array 7935 2017-07-11 28406950 Kim J 2017-04-13 PLoS One www.ncbi.nlm.nih.gov/pubmed/28406950 Interaction of iron status with single nucleotide polymorphisms on incidence of type 2 diabetes. Type 2 diabetes 1,895 Korean ancestry cases, 6,040 Korean ancestry controls NA Affymetrix [352228] 2 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST004305 Genome-wide genotyping array 7935 2017-07-12 28453575 Hodonsky CJ 2017-04-28 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28453575 Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos. Hematocrit 12,502 Hispanic/Latino individuals 7,106 Hispanic/Latino individuals Illumina [27801688] (imputed) 3 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST004330 Genome-wide genotyping array 12502 2017-07-12 28453575 Hodonsky CJ 2017-04-28 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28453575 Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos. Mean corpuscular hemoglobin concentration 12,502 Hispanic/Latino individuals 4,772 Hispanic/Latino individuals Illumina [27801688] (imputed) 9 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST004329 Genome-wide genotyping array 12502 2017-07-12 28453575 Hodonsky CJ 2017-04-28 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28453575 Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos. Red blood cell count 12,502 Hispanic/Latino individuals 4,772 Hispanic/Latino individuals Illumina [27801688] (imputed) 5 erythrocyte count http://www.ebi.ac.uk/efo/EFO_0004305 GCST004332 Genome-wide genotyping array 12502 2017-07-12 28453575 Hodonsky CJ 2017-04-28 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28453575 Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos. Hemoglobin 12,502 Hispanic/Latino individuals 7,106 Hispanic/Latino individuals Illumina [27801688] (imputed) 3 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST004331 Genome-wide genotyping array 12502 2017-07-12 28453575 Hodonsky CJ 2017-04-28 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28453575 Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos. Red cell distribution width 12,502 Hispanic/Latino individuals 4,772 Hispanic/Latino individuals Illumina [27801688] (imputed) 1 red blood cell distribution width http://www.ebi.ac.uk/efo/EFO_0005192 GCST004333 Genome-wide genotyping array 12502 2017-07-12 28453575 Hodonsky CJ 2017-04-28 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28453575 Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos. Mean corpuscular hemoglobin 12,502 Hispanic/Latino individuals 4,772 Hispanic/Latino individuals Illumina [27801688] (imputed) 14 mean corpuscular hemoglobin http://www.ebi.ac.uk/efo/EFO_0004527 GCST004334 Genome-wide genotyping array 12502 2017-07-12 28453575 Hodonsky CJ 2017-04-28 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28453575 Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos. Mean corpuscular volume 12,502 Hispanic/Latino individuals 4,772 Hispanic/Latino individuals Illumina [27801688] (imputed) 16 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST004335 Genome-wide genotyping array 12502 2017-10-06 28598419 Hong X 2017-06-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28598419 Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth. Preterm birth (maternal effect) (maternal pre-pregnancy BMI interaction) 329 African American normal weight preterm birth mothers, 514 African American normal weight term birth mothers, 463 African American overweight or obese preterm birth mothers, 580 African American overweight or obese term birth mothers NA Affymetrix, Illumina [9929081] (imputed) 1 body mass index, premature birth, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0003917, http://www.ebi.ac.uk/efo/EFO_0005939 GCST004842 Genome-wide genotyping array 1886 2017-10-06 28598419 Hong X 2017-06-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28598419 Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth. Preterm birth (maternal effect) 698 African American preterm birth mothers, 1,035 African American term birth mothers 307 African American preterm birth mothers, 475 African American term birth mothers, 318 European ancestry preterm birth mothers, 365 European ancestry term birth mothers Illumina [13317377] (imputed) 0 premature birth, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0003917, http://www.ebi.ac.uk/efo/EFO_0005939 GCST004841 Genome-wide genotyping array 1733 2017-10-06 28598419 Hong X 2017-06-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28598419 Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth. Spontaneous preterm birth (maternal effect) 461 African American spontaneous preterm birth mothers, 1,035 African American term birth mothers NA Illumina [13317377] (imputed) 2 spontaneous preterm birth, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0006917, http://www.ebi.ac.uk/efo/EFO_0005939 GCST004845 Genome-wide genotyping array 1496 2017-10-06 28598419 Hong X 2017-06-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28598419 Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth. Gestational age at birth (maternal effect) 698 African American preterm birth mothers, 1,035 African American term birth mothers NA Illumina [13317377] (imputed) 3 gestational age, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0005112, http://www.ebi.ac.uk/efo/EFO_0005939 GCST004844 Genome-wide genotyping array 1733 2017-10-06 28598419 Hong X 2017-06-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28598419 Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth. Preterm birth (maternal effect) (maternal pre-pregnancy BMI interaction) 447 African American normal weight term birth mothers, 498 African American overweight or obese term birth mothers, 268 African American normal weight preterm birth mothers, 373 African American overweight or obese preterm birth mothers 67 African American normal weight term birth mothers, 82 African American overweight or obese term birth mothers, 61 African American normal weight preterm birth mothers, 90 African American overweight or obese preterm birth mothers, 247 European ancestry normal weight term birth mothers, 118 European ancestry overweight or obese term birth mothers, 192 European ancestry normal weight preterm birth mothers, 126 European ancestry overweight or obese preterm birth mothers Illumina [13317377] (imputed) 0 body mass index, premature birth, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0003917, http://www.ebi.ac.uk/efo/EFO_0005939 GCST004843 Genome-wide genotyping array 1586 2017-10-13 28916551 Liu Y 2017-09-15 J Rheumatol www.ncbi.nlm.nih.gov/pubmed/28916551 Genetic Determinants of Radiographic Knee Osteoarthritis in African Americans. Knee osteoarthritis 742 African American cases, 475 African American controls NA Illumina [8300000] (imputed) 6 osteoarthritis, knee http://www.ebi.ac.uk/efo/EFO_0004616 GCST004881 Genome-wide genotyping array 1217 2017-09-11 28604731 Hammerschlag AR 2017-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28604731 Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits. Insomnia complaints 12,863 European ancestry male cases, 19,521 European ancestry female cases, 40,776 European ancestry male controls, 39,846 European ancestry female controls 1,983 Icelandic ancestry male cases, 1,791 Icelandic ancestry female cases, 2,064 Icelandic ancestry male controls, 1,727 Icelandic ancestry female controls Affymetrix [at least 12428592] (imputed) 2 insomnia http://www.ebi.ac.uk/efo/EFO_0004698 GCST004695 Genome-wide genotyping array 113006 2017-09-11 28604731 Hammerschlag AR 2017-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28604731 Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits. Sleep duration 112,411 European ancestry male individuals NA Affymetrix [at least 12428592] (imputed) 3 sleep duration http://www.ebi.ac.uk/efo/EFO_0005271 GCST004694 Genome-wide genotyping array 112411 2017-09-11 28604731 Hammerschlag AR 2017-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28604731 Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits. Insomnia complaints (sex interaction) 12,863 European ancestry male cases, 19,521 European ancestry female cases, 40,776 European ancestry male controls, 39,846 European ancestry female controls NA Affymetrix [at least 12428592] (imputed) 0 insomnia http://www.ebi.ac.uk/efo/EFO_0004698 GCST004700 Genome-wide genotyping array 113006 2017-09-11 28604731 Hammerschlag AR 2017-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28604731 Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits. Insomnia complaints (continuous) 12,863 European ancestry male cases, 19,521 European ancestry female cases, 40,776 European ancestry male controls, 39,846 European ancestry female controls NA Affymetrix [at least 12428592] (imputed) 1 insomnia http://www.ebi.ac.uk/efo/EFO_0004698 GCST004701 Genome-wide genotyping array 113006 2017-09-11 28604731 Hammerschlag AR 2017-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28604731 Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits. Insomnia complaints (dichotomous) 32,384 European ancestry cases, 27,128 European ancestry controls NA Affymetrix [at least 12428592] (imputed) 1 insomnia http://www.ebi.ac.uk/efo/EFO_0004698 GCST004702 Genome-wide genotyping array 59512 2017-09-11 28604731 Hammerschlag AR 2017-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28604731 Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits. Chronotype 101,185 European ancestry individuals NA Affymetrix [at least 12428592] (imputed) 9 circadian rhythm http://www.ebi.ac.uk/efo/EFO_0004354 GCST004696 Genome-wide genotyping array 101185 2017-09-11 28604731 Hammerschlag AR 2017-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28604731 Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits. Ease of getting up in the morning 112,866 European ancestry individuals NA Affymetrix [at least 12428592] (imputed) 5 chronotype measurement http://www.ebi.ac.uk/efo/EFO_0008328 GCST004697 Genome-wide genotyping array 112866 2017-09-11 28604731 Hammerschlag AR 2017-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28604731 Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits. Daytime nap 113,054 European ancestry cases and controls NA Affymetrix [at least 12428592] (imputed) 4 daytime rest measurement http://www.ebi.ac.uk/efo/EFO_0007828 GCST004693 Genome-wide genotyping array 113054 2017-09-11 28604731 Hammerschlag AR 2017-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28604731 Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits. Snoring 105,377 European ancestry cases and controls NA Affymetrix [at least 12428592] (imputed) 1 snoring measurement http://www.ebi.ac.uk/efo/EFO_0008341 GCST004698 Genome-wide genotyping array 105377 2017-09-11 28604731 Hammerschlag AR 2017-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28604731 Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits. Daytime sleepiness 112,717 European ancestry cases and controls NA Affymetrix [at least 12428592] (imputed) 6 excessive daytime sleepiness measurement http://www.ebi.ac.uk/efo/EFO_0007875 GCST004699 Genome-wide genotyping array 112717 2018-11-02 28604731 Hammerschlag AR 2017-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28604731 Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits. Insomnia complaints 19,521 European ancestry female cases, 39,846 European ancestry female controls 1,983 Icelandic ancestry male cases, 1,791 Icelandic ancestry female cases, 2,064 Icelandic ancestry male controls, 1,727 Icelandic ancestry female controls Affymetrix [at least 12428592] (imputed) 1 insomnia http://www.ebi.ac.uk/efo/EFO_0004698 GCST006487 Genome-wide genotyping array 59367 2018-11-02 28604731 Hammerschlag AR 2017-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28604731 Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits. Insomnia complaints 12,863 European ancestry male cases, 40,776 European ancestry male controls 1,983 Icelandic ancestry male cases, 1,791 Icelandic ancestry female cases, 2,064 Icelandic ancestry male controls, 1,727 Icelandic ancestry female controls Affymetrix [at least 12428592] (imputed) 2 insomnia http://www.ebi.ac.uk/efo/EFO_0004698 GCST006488 Genome-wide genotyping array 53639 2017-09-14 28610988 Kerr KF 2017-06-10 Heart Rhythm www.ncbi.nlm.nih.gov/pubmed/28610988 Genome-wide association study of heart rate and its variability in Hispanic/Latino cohorts. Heart rate 13,184 Hispanic/Latino individuals 7,073 European ancestry individuals, 4,771 African American individuals Affymetrix, Illumina [16967914] (imputed) 2 heart rate http://www.ebi.ac.uk/efo/EFO_0004326 GCST004715 Genome-wide genotyping array 13184 2017-09-14 28610988 Kerr KF 2017-06-10 Heart Rhythm www.ncbi.nlm.nih.gov/pubmed/28610988 Genome-wide association study of heart rate and its variability in Hispanic/Latino cohorts. Heart rate variability traits (RMSSD) 13,767 Hispanic/Latino individuals 4,730 European ancestry individuals, 2,908 African American individuals Affymetrix, Illumina [17209892] (imputed) 2 heart rate variability measurement http://www.ebi.ac.uk/efo/EFO_0008003 GCST004716 Genome-wide genotyping array 13767 2017-09-14 28610988 Kerr KF 2017-06-10 Heart Rhythm www.ncbi.nlm.nih.gov/pubmed/28610988 Genome-wide association study of heart rate and its variability in Hispanic/Latino cohorts. Heart rate variability traits (SDNN) 13,184 Hispanic/Latino individuals 7,073 European ancestry individuals, 2,908 African American individuals Affymetrix, Illumina [17209740] (imputed) 3 heart rate variability measurement http://www.ebi.ac.uk/efo/EFO_0008003 GCST004714 Genome-wide genotyping array 13184 2017-08-23 28630421 Li D 2017-06-19 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28630421 A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling. Anorexia nervosa (excluding migration to or from binge-eating disorder or bulimia nervosa) 692 European ancestry female cases and 3,570 European ancestry female controls Cases and controls (see Boraska et al, 2014) Illumina [507999] 1 anorexia nervosa http://www.ebi.ac.uk/efo/EFO_0004215 GCST004585 Genome-wide genotyping array 4262 2017-07-21 28627999 Ikram MA 2017-06-19 J Cereb Blood Flow Metab www.ncbi.nlm.nih.gov/pubmed/28627999 Heritability and genome-wide associations studies of cerebral blood flow in the general population. Cerebral blood flow 4,472 Dutch individuals 1,350 Icelandic individuals Illumina [NR] 1 cerebral blood flow measurement http://www.ebi.ac.uk/efo/EFO_0007980 GCST004376 Genome-wide genotyping array 4472 2017-08-31 28604728 Litchfield K 2017-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28604728 Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor. Testicular germ cell tumor 5,518 European ancestry cases, 19,055 European ancestry controls 1,801 European ancestry cases, 4,027 European ancestry controls Illumina [at least 371504] (imputed) 43 Testicular Germ Cell Tumor http://www.ebi.ac.uk/efo/EFO_1000566 GCST004635 Genome-wide genotyping array 24573 2018-02-27 29292387 Turley P 2018-01-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29292387 Multi-trait analysis of genome-wide association summary statistics using MTAG. Depressive symptoms (MTAG) 354,862 European ancestry individuals NA Illumina [NR] (imputed) 64 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST005323 Genome-wide genotyping array 354862 2018-02-27 29292387 Turley P 2018-01-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29292387 Multi-trait analysis of genome-wide association summary statistics using MTAG. Subjective well-being (MTAG) 388,538 European ancestry individuals NA Illumina [NR] (imputed) 49 wellbeing measurement http://www.ebi.ac.uk/efo/EFO_0007869 GCST005325 Genome-wide genotyping array 388538 2018-02-27 29292387 Turley P 2018-01-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29292387 Multi-trait analysis of genome-wide association summary statistics using MTAG. Neuroticism (MTAG) 168,105 European ancestry individuals NA Illumina [NR] (imputed) 37 neuroticism measurement http://www.ebi.ac.uk/efo/EFO_0007660 GCST005326 Genome-wide genotyping array 168105 2018-02-27 29292387 Turley P 2018-01-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29292387 Multi-trait analysis of genome-wide association summary statistics using MTAG. Neuroticism 168,105 European ancestry individuals NA Illumina [NR] (imputed) 12 neuroticism measurement http://www.ebi.ac.uk/efo/EFO_0007660 GCST005327 Genome-wide genotyping array 168105 2018-02-27 29292387 Turley P 2018-01-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29292387 Multi-trait analysis of genome-wide association summary statistics using MTAG. Depressive symptoms 354,862 European ancestry individuals NA Illumina [NR] (imputed) 32 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST005324 Genome-wide genotyping array 354862 2018-02-27 29292387 Turley P 2018-01-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29292387 Multi-trait analysis of genome-wide association summary statistics using MTAG. Subjective well-being 388,538 European ancestry individuals NA Illumina [NR] (imputed) 13 wellbeing measurement http://www.ebi.ac.uk/efo/EFO_0007869 GCST005328 Genome-wide genotyping array 388538 2017-08-03 28447399 Jia P 2017-04-26 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/28447399 Genome-wide association study of HIV-associated neurocognitive disorder (HAND): A CHARTER group study. Neurocognitive impairment in HIV-1 infection (continuous) 490 African American individuals, 443 European ancestry individuals, 99 Hispanic individuals, 17 individuals NA Affymetrix [NR] 6 cognitive impairment measurement http://www.ebi.ac.uk/efo/EFO_0007998 GCST004406 Genome-wide genotyping array 1049 2017-08-03 28447399 Jia P 2017-04-26 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/28447399 Genome-wide association study of HIV-associated neurocognitive disorder (HAND): A CHARTER group study. HIV-associated neurocognitive disorder (mild neurocognitive disorder or asymptomatic neurocognitive impairment) 155 African American asymptomatic neurocognitive impairment cases, 150 European ancestry asymptomatic neurocognitive impairment cases, 49 Hispanic asymptomatic neurocognitive impairment cases, 5 asymptomatic neurocognitive impairment cases, 30 African American mild neurocognitive disorder cases, 45 European ancestry mild neurocognitive disorder cases, 17 Hispanic mild neurocognitive disorder cases, 297 African American controls, 230 European ancestry controls, 29 Hispanic controls, 11 controls NA Affymetrix [NR] 4 HIV-associated neurocognitive disorder, mild neurocognitive disorder, asymptomatic neurocognitive impairment http://www.ebi.ac.uk/efo/EFO_0007948, http://www.ebi.ac.uk/efo/EFO_0007982, http://www.ebi.ac.uk/efo/EFO_0007983 GCST004411 Genome-wide genotyping array 1018 2017-08-03 28447399 Jia P 2017-04-26 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/28447399 Genome-wide association study of HIV-associated neurocognitive disorder (HAND): A CHARTER group study. HIV-associated neurocognitive disorder (mild neurocognitive disorder) 30 African American cases, 45 European ancestry cases, 17 Hispanic cases, 297 African American controls, 230 European ancestry controls, 29 Hispanic controls, 11 controls NA Affymetrix [NR] 3 HIV-associated neurocognitive disorder, mild neurocognitive disorder http://www.ebi.ac.uk/efo/EFO_0007948, http://www.ebi.ac.uk/efo/EFO_0007982 GCST004408 Genome-wide genotyping array 659 2017-08-03 28447399 Jia P 2017-04-26 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/28447399 Genome-wide association study of HIV-associated neurocognitive disorder (HAND): A CHARTER group study. HIV-associated neurocognitive disorder 192 African American cases, 213 European ancestry cases, 70 Hispanic cases, 6 unknown ancestry cases, 297 African American controls, 230 European ancestry controls, 29 Hispanic controls, 11 controls NA Affymetrix [NR] 2 HIV-associated neurocognitive disorder http://www.ebi.ac.uk/efo/EFO_0007948 GCST004409 Genome-wide genotyping array 1048 2017-08-03 28447399 Jia P 2017-04-26 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/28447399 Genome-wide association study of HIV-associated neurocognitive disorder (HAND): A CHARTER group study. Neurocognitive impairment in HIV-1 infection (dichotomous) 140 African American cases, 167 European ancestry cases, 53 Hispanic cases, 6 cases, 350 African American controls, 276 European ancestry controls, 46 Hispanic controls, 11 controls NA Affymetrix [NR] 9 cognitive impairment measurement http://www.ebi.ac.uk/efo/EFO_0007998 GCST004407 Genome-wide genotyping array 1049 2017-08-03 28447399 Jia P 2017-04-26 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/28447399 Genome-wide association study of HIV-associated neurocognitive disorder (HAND): A CHARTER group study. HIV-associated neurocognitive disorder (asymptomatic neurocogntive impairment) 155 African American cases, 150 European ancestry cases, 49 Hispanic cases, 5 cases, 297 African American controls, 230 European ancestry controls, 29 Hispanic controls, 11 controls NA Affymetrix [NR] 3 HIV-associated neurocognitive disorder, asymptomatic neurocognitive impairment http://www.ebi.ac.uk/efo/EFO_0007948, http://www.ebi.ac.uk/efo/EFO_0007983 GCST004410 Genome-wide genotyping array 926 2017-06-23 28424481 Sugiura-Ogasawara M 2017-04-20 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/28424481 The first genome-wide association study identifying new susceptibility loci for obstetric antiphospholipid syndrome. Obstetric antiphospholipid syndrome 115 Japanese ancestry female cases, 419 Japanese ancestry male and female controls NA Affymetrix [426344] 15 antiphospholipid syndrome http://www.ebi.ac.uk/efo/EFO_0002689 GCST004227 Genome-wide genotyping array 534 2017-07-10 28425483 Qiu F 2017-04-20 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28425483 A genome-wide association study identifies six novel risk loci for primary biliary cholangitis. Primary biliary cholangitis 1,122 Han Chinese ancestry cases, 4,036 Han Chinese ancestry controls 907 Han Chinese ancestry cases, 2,127 Han Chinese ancestry controls Illumina [776516] 22 primary biliary cirrhosis http://www.ebi.ac.uk/efo/EFO_1001486 GCST004302 Genome-wide genotyping array 5158 2017-07-04 28441426 White CC 2017-04-25 PLoS Med www.ncbi.nlm.nih.gov/pubmed/28441426 Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data. Residual cognition 979 European ancestry individuals NA Affymetrix, Illumina [~ 7000000] (imputed) 9 cognition, aging http://www.ebi.ac.uk/efo/EFO_0003925, http://purl.obolibrary.org/obo/GO_0007568 GCST004291 Genome-wide genotyping array 979 2017-08-07 27082954 Ward-Caviness CK 2016-04-15 PLoS One www.ncbi.nlm.nih.gov/pubmed/27082954 Genetic Variants in the Bone Morphogenic Protein Gene Family Modify the Association between Residential Exposure to Traffic and Peripheral Arterial Disease. Peripheral arterial disease (traffic-related air pollution interaction) 104 European ancestry cases, 1,519 European ancestry controls, 34 African American cases, 520 African American controls NA Illumina [905956] 159 peripheral arterial disease, traffic air pollution measurement http://www.ebi.ac.uk/efo/EFO_0004265, http://www.ebi.ac.uk/efo/EFO_0007908 GCST004482 Genome-wide genotyping array 2177 2018-04-25 23603761 Hinks A 2013-04-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23603761 Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis. Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) 2,816 European ancestry cases, 13,056 European ancestry controls NA Illumina [123003] 31 systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis http://www.ebi.ac.uk/efo/EFO_1001999, http://www.ebi.ac.uk/efo/EFO_1002020, http://www.ebi.ac.uk/efo/EFO_1002019 GCST005528 Targeted genotyping array [ImmunoChip] 15872 2017-11-06 28918882 Wattacheril J 2017-09-14 J Pediatr www.ncbi.nlm.nih.gov/pubmed/28918882 Genome-Wide Associations Related to Hepatic Histology in Nonalcoholic Fatty Liver Disease in Hispanic Boys. Pediatric non-alcoholic fatty liver disease activity score 208 Hispanic boys NA Illumina [up to 624297] 1 non-alcoholic fatty liver disease severity measurement http://www.ebi.ac.uk/efo/EFO_0008421 GCST004942 Genome-wide genotyping array 208 2017-11-06 28918882 Wattacheril J 2017-09-14 J Pediatr www.ncbi.nlm.nih.gov/pubmed/28918882 Genome-Wide Associations Related to Hepatic Histology in Nonalcoholic Fatty Liver Disease in Hispanic Boys. Liver fibrosis in pediatric non-alcoholic fatty acid liver disease 208 Hispanic boys NA Illumina [up to 624297] 5 Hepatic fibrosis http://purl.obolibrary.org/obo/HP_0001395 GCST004938 Genome-wide genotyping array 208 2017-11-06 28918882 Wattacheril J 2017-09-14 J Pediatr www.ncbi.nlm.nih.gov/pubmed/28918882 Genome-Wide Associations Related to Hepatic Histology in Nonalcoholic Fatty Liver Disease in Hispanic Boys. Pediatric nonalcoholic steatohepatitis 46 Hispanic boy definite NASH cases, 110 Hispanic boy borderline NASH controls NA Illumina [up to 624297] 2 non-alcoholic steatohepatitis http://www.ebi.ac.uk/efo/EFO_1001249 GCST004943 Genome-wide genotyping array 156 2017-11-20 28921760 Chenoweth MJ 2017-09-16 Addiction www.ncbi.nlm.nih.gov/pubmed/28921760 Genome-wide association study of a nicotine metabolism biomarker in African American smokers: impact of chromosome 19 genetic influences. Nicotine metabolite ratio in current smokers 954 African American individuals 480 African American individuals Illumina [at least 17919969] (imputed) 3 nicotine metabolite ratio http://www.ebi.ac.uk/efo/EFO_0007794 GCST004976 Genome-wide genotyping array 954 2017-11-17 28922980 Konte B 2017-09-19 World J Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/28922980 A genome-wide association study of early gamma-band response in a schizophrenia case-control sample. Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia 74 European ancestry cases, 241 European ancestry controls NA Illumina [304635] 3 gamma wave measurement http://www.ebi.ac.uk/efo/EFO_0008388 GCST004953 Genome-wide genotyping array 315 2018-08-03 28927820 Sugier PE 2017-09-16 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/28927820 A novel role for ciliary function in atopy: ADGRV1 and DNAH5 interactions. Atopy 925 European ancestry cases, 735 European ancestry controls 641 French Canadian (founder/population isolate) cases, 497 French Canadian (founder/population isolate) controls, 106 cases, 340 controls Illumina [501167] 2 atopy http://www.ebi.ac.uk/efo/EFO_0002686 GCST006040 Genome-wide genotyping array 1660 2017-10-17 28937693 Clarke TK 2017-07-25 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/28937693 Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117). Alcohol consumption 59,088 European ancestry females, 53,029 European ancestry males NA Affymetrix [12489781] (imputed) 20 alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0007878 GCST004886 Genome-wide genotyping array 112117 2017-10-17 28937693 Clarke TK 2017-07-25 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/28937693 Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117). Alcohol consumption in current drinkers 108,309 European ancestry individuals NA Affymetrix [12489781] (imputed) 8 alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0007878 GCST004887 Genome-wide genotyping array 108309 2017-09-13 28598434 Scelo G 2017-06-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28598434 Genome-wide association study identifies multiple risk loci for renal cell carcinoma. Renal cell carcinoma 10,784 European ancestry cases, 20,406 European ancestry controls 3,182 European ancestry cases, 6,301 European ancestry controls Illumina [7437091] (imputed) 26 renal cell carcinoma http://www.ebi.ac.uk/efo/EFO_0000681 GCST004710 Genome-wide genotyping array 31190 2017-09-15 28613276 Nolte IM 2017-06-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28613276 Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Heart rate variability traits (SDNN) 27,850 European ancestry individuals 24,125 European ancestry individuals, 11,234 Hispanic/Latino individuals, 6,899 African American individuals Affymetrix, Illumina, Perlegen [at least 2135543] (imputed) 23 heart rate variability measurement http://www.ebi.ac.uk/efo/EFO_0008003 GCST004734 Genome-wide genotyping array 27850 2017-09-15 28613276 Nolte IM 2017-06-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28613276 Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Heart rate variability traits (RMSSD) 26,523 European ancestry individuals 20,429 European ancestry individuals, 11,234 Hispanic/Latino individuals, 6,895 African American individuals Affymetrix, Illumina, Perlegen [at least 2135543] (imputed) 22 heart rate variability measurement http://www.ebi.ac.uk/efo/EFO_0008003 GCST004733 Genome-wide genotyping array 26523 2017-09-15 28613276 Nolte IM 2017-06-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28613276 Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Heart rate variability traits (pvRSA/HF) 24,088 European ancestry individuals 9,377 European ancestry individuals, 404 Hispanic/Latino individuals, 1,901 African American individuals Affymetrix, Illumina, Perlegen [at least 2135543] (imputed) 12 heart rate variability measurement http://www.ebi.ac.uk/efo/EFO_0008003 GCST004732 Genome-wide genotyping array 24088 2018-02-20 29385134 Kawaguchi T 2018-01-31 PLoS One www.ncbi.nlm.nih.gov/pubmed/29385134 Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers. Nonalcoholic steatohepatitis-derived hepatocellular carcinoma 58 Japanese ancestry cases, 7,672 Japanese ancestry controls NA Illumina [93606] 3 hepatocellular carcinoma, non-alcoholic steatohepatitis http://www.ebi.ac.uk/efo/EFO_0000182, http://www.ebi.ac.uk/efo/EFO_1001249 GCST005309 Genome-wide genotyping array 7730 2018-02-20 29385134 Kawaguchi T 2018-01-31 PLoS One www.ncbi.nlm.nih.gov/pubmed/29385134 Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers. Brunt stage in nonalcoholic fatty liver disease 474 Japanese ancestry cases NA Illumina [93606] 0 non-alcoholic fatty liver disease severity measurement http://www.ebi.ac.uk/efo/EFO_0008421 GCST005307 Genome-wide genotyping array 474 2018-02-20 29385134 Kawaguchi T 2018-01-31 PLoS One www.ncbi.nlm.nih.gov/pubmed/29385134 Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers. Brunt grade in nonalcoholic fatty liver disease 567 Japanese ancestry cases NA Illumina [93606] 0 non-alcoholic fatty liver disease severity measurement http://www.ebi.ac.uk/efo/EFO_0008421 GCST005310 Genome-wide genotyping array 567 2018-02-20 29385134 Kawaguchi T 2018-01-31 PLoS One www.ncbi.nlm.nih.gov/pubmed/29385134 Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers. Hepatocyte fat droplet content in nonalcoholic fatty liver disease 834 Japanese ancestry cases NA Illumina [93606] 0 non-alcoholic fatty liver disease severity measurement http://www.ebi.ac.uk/efo/EFO_0008421 GCST005311 Genome-wide genotyping array 834 2018-02-20 29385134 Kawaguchi T 2018-01-31 PLoS One www.ncbi.nlm.nih.gov/pubmed/29385134 Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers. Nonalcoholic fatty liver disease 902 Japanese ancestry cases, 7,672 Japanese ancestry controls NA Illumina [93606] 7 non-alcoholic fatty liver disease http://www.ebi.ac.uk/efo/EFO_0003095 GCST005308 Genome-wide genotyping array 8574 2017-09-14 28604732 Wang Z 2017-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28604732 Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor. Testicular germ cell tumor 3,558 European ancestry cases, 13,970 European ancestry controls NA Illumina [9210350] (imputed) 37 Testicular Germ Cell Tumor http://www.ebi.ac.uk/efo/EFO_1000566 GCST004713 Genome-wide genotyping array 17528 2017-10-16 28924153 Chang X 2017-09-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28924153 Common variants in MMP20 at 11q22.2 predispose to 11q deletion and neuroblastoma risk. Neuroblastoma (11q deletion) 113 European ancestry cases, 5,109 European ancestry controls 44 European ancestry cases, 1,902 European ancestry controls Illumina [NR] 1 neuroblastoma http://www.ebi.ac.uk/efo/EFO_0000621 GCST004883 Genome-wide genotyping array 5222 2017-10-16 28924153 Chang X 2017-09-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28924153 Common variants in MMP20 at 11q22.2 predispose to 11q deletion and neuroblastoma risk. Neuroblastoma (11q deletion vs 11q undeleted and MYCN amplification) 113 European ancestry 11q-deletion neuroblastoma cases, 78 European ancestry 11q-undeleted neuroblastoma cases, 204 European ancestry MYCN-amplification neuroblastoma cases NA Illumina [NR] 0 neuroblastoma http://www.ebi.ac.uk/efo/EFO_0000621 GCST004882 Genome-wide genotyping array 417 2017-10-16 28924153 Chang X 2017-09-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28924153 Common variants in MMP20 at 11q22.2 predispose to 11q deletion and neuroblastoma risk. Neuroblastoma (1p deletion) 69 European ancestry cases, 5,109 European ancestry controls NA Illumina [NR] 1 neuroblastoma http://www.ebi.ac.uk/efo/EFO_0000621 GCST004884 Genome-wide genotyping array 5178 2017-10-16 28924153 Chang X 2017-09-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28924153 Common variants in MMP20 at 11q22.2 predispose to 11q deletion and neuroblastoma risk. Neuroblastoma (MYCN amplification) 260 European ancestry cases, 5,109 European ancestry controls NA Illumina [NR] 2 neuroblastoma http://www.ebi.ac.uk/efo/EFO_0000621 GCST004885 Genome-wide genotyping array 5369 2018-08-03 28921602 Lee MH 2017-09-16 Hepatology www.ncbi.nlm.nih.gov/pubmed/28921602 Human leukocyte antigen variants and risk of hepatocellular carcinoma modified by hepatitis C virus genotypes: A genome-wide association study. Hepatocellular carcinoma in hepatitis C infection 502 Chinese ancestry cases, 749 Chinese ancestry controls 669 Chinese ancestry cases, 429 Chinese ancestry controls Affymetrix [576032] 1 hepatocellular carcinoma http://www.ebi.ac.uk/efo/EFO_0000182 GCST006037 Genome-wide genotyping array 1251 2017-07-18 28240269 Suhre K 2017-02-27 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28240269 Connecting genetic risk to disease end points through the human blood plasma proteome. Blood protein levels 997 European ancestry individuals 338 Arab, South Asian and Filipino ancestry individuals Affymetrix [509946] 590 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST004365 Genome-wide genotyping array 997 2017-10-23 28931804 Benyamin B 2017-09-20 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28931804 Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis (sporadic) 1,234 Chinese ancestry cases, 2,850 Chinese ancestry controls, 12,577 European ancestry cases, 23,475 European ancestry controls 576 cases, 683 controls Illumina [at least 6613544] (imputed) 4 sporadic amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0001357 GCST004901 Genome-wide genotyping array 40136 2019-08-20 28931804 Benyamin B 2017-09-20 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28931804 Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis (sporadic) 1,234 Chinese ancestry cases, 2,850 Chinese ancestry controls, 12,577 European ancestry cases, 23,475 European ancestry controls 576 cases, 683 controls Illumina [at least 6613544] (imputed) 0 sporadic amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0001357 GCST008472 Genome-wide genotyping array 40136 2018-08-30 28941034 Smith CE 2017-09-21 Mol Nutr Food Res www.ncbi.nlm.nih.gov/pubmed/28941034 Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent. BMI x dairy intake interaction (1df interaction test) up to 25,513 European ancestry individuals up to 17,675 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 0 energy intake, body mass index http://www.ebi.ac.uk/efo/EFO_0003939, http://www.ebi.ac.uk/efo/EFO_0004340 GCST006173 Genome-wide genotyping array 25513 2018-02-21 26414677 Day FR 2015-11-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26414677 Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Menopause (age at onset) up to 69,626 European ancestry women NA Affymetrix, Illumina [~ 2600000] (imputed) 51 age at menopause http://www.ebi.ac.uk/efo/EFO_0004704 GCST005312 Genome-wide genotyping array 69626 2018-05-02 26414677 Day FR 2015-11-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26414677 Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Menopause (age at onset) up to 2,545 European ancestry women up to 46,638 European ancestry women Illumina [Exome array] 2 age at menopause http://www.ebi.ac.uk/efo/EFO_0004704 GCST005560 Genome-wide genotyping array, Exome genotyping array [Exome array] 2545 2017-09-05 28632202 Witt SH 2017-06-20 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/28632202 Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia. Borderline personality disorder 998 European ancestry cases, 1,545 European ancestry controls NA Illumina [10736316] (imputed) 28 Borderline personality disorder http://purl.obolibrary.org/obo/HP_0012076 GCST004641 Genome-wide genotyping array 2543 2017-09-11 28628665 Sobota RS 2017-06-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28628665 A chromosome 5q31.1 locus associates with tuberculin skin test reactivity in HIV-positive individuals from tuberculosis hyper-endemic regions in east Africa. Resistance to Mycobacterium tuberculosis in HIV-positive individuals measured by a negative tuberculin skin test (continuous) 244 cases, 225 controls NA Illumina [542585] 4 tuberculin skin test reactivity measurement, decreased susceptibility to bacterial infection http://www.ebi.ac.uk/efo/EFO_0008307, http://www.ebi.ac.uk/efo/EFO_0008322 GCST004689 Genome-wide genotyping array 469 2017-09-11 28628665 Sobota RS 2017-06-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28628665 A chromosome 5q31.1 locus associates with tuberculin skin test reactivity in HIV-positive individuals from tuberculosis hyper-endemic regions in east Africa. Resistance to Mycobacterium tuberculosis in HIV-positive individuals measured by a negative tuberculin skin test (dichotomous) 244 cases, 225 controls NA Illumina [542585] 3 tuberculin skin test reactivity measurement, decreased susceptibility to bacterial infection http://www.ebi.ac.uk/efo/EFO_0008307, http://www.ebi.ac.uk/efo/EFO_0008322 GCST004690 Genome-wide genotyping array 469 2017-05-30 28112199 Law PJ 2017-01-23 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28112199 Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci. B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) 1,842 European ancestry chronic lymphocytic leukemia cases, 1,465 European ancestry Hodgkin lymphoma cases, 3,790 European ancestry multiple myeloma cases, 7,324 European ancestry controls NA Illumina [10806625] (imputed) 20 Hodgkins lymphoma, multiple myeloma, chronic lymphocytic leukemia http://www.ebi.ac.uk/efo/EFO_0000183, http://www.ebi.ac.uk/efo/EFO_0001378, http://www.ebi.ac.uk/efo/EFO_0000095 GCST004099 Genome-wide genotyping array 14421 2017-06-29 28360221 Boger CA 2017-03-30 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/28360221 NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality. Blood osmolality (transformed sodium) 45,889 European ancestry individuals, up to 8,765 Asian Indian ancestry individuals, up to 7,215 African ancestry individuals 17,637 European ancestry individuals Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 37 blood osmolality measurement http://www.ebi.ac.uk/efo/EFO_0007967 GCST004267 Genome-wide genotyping array 61869 2018-01-09 29059430 Morton LM 2017-11-01 J Natl Cancer Inst www.ncbi.nlm.nih.gov/pubmed/29059430 Genome-Wide Association Study to Identify Susceptibility Loci That Modify Radiation-Related Risk for Breast Cancer After Childhood Cancer. Breast cancer in childhood cancer survivors treated with less than 10 gray radiotherapy 69 European ancestry cases, 2,144 European ancestry controls NA Affymetrix, Illumina [16958466] (imputed) 3 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST005110 Genome-wide genotyping array 2213 2018-01-09 29059430 Morton LM 2017-11-01 J Natl Cancer Inst www.ncbi.nlm.nih.gov/pubmed/29059430 Genome-Wide Association Study to Identify Susceptibility Loci That Modify Radiation-Related Risk for Breast Cancer After Childhood Cancer. Breast cancer in childhood cancer survivors treated with more than 10 gray radiotherapy 131 European ancestry cases, 493 European ancestry controls NA Affymetrix, Illumina [16958466] (imputed) 3 response to radiation, breast carcinoma http://purl.obolibrary.org/obo/GO_0009314, http://www.ebi.ac.uk/efo/EFO_0000305 GCST005112 Genome-wide genotyping array 624 2018-01-09 29059430 Morton LM 2017-11-01 J Natl Cancer Inst www.ncbi.nlm.nih.gov/pubmed/29059430 Genome-Wide Association Study to Identify Susceptibility Loci That Modify Radiation-Related Risk for Breast Cancer After Childhood Cancer. Breast cancer in childhood cancer survivors 207 European ancestry female cases, 2,774 European ancestry female controls NA Affymetrix, Illumina [16958466] (imputed) 5 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST005111 Genome-wide genotyping array 2981 2017-11-20 29051540 Marenholz I 2017-10-20 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29051540 Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy. Cow's milk allergy 169 European ancestry cases, 2,387 European ancestry controls 390 European ancestry cases, 2,510 European ancestry controls Illumina [5405832] (imputed) 0 milk allergy measurement http://www.ebi.ac.uk/efo/EFO_0007019 GCST004978 Genome-wide genotyping array 2556 2017-11-20 29051540 Marenholz I 2017-10-20 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29051540 Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy. Food allergy 497 European ancestry cases, 2,387 European ancestry controls 1,050 European ancestry cases, 2,510 European ancestry controls Illumina [5405832] (imputed) 2 food allergy measurement http://www.ebi.ac.uk/efo/EFO_0007016 GCST004979 Genome-wide genotyping array 2884 2017-11-20 29051540 Marenholz I 2017-10-20 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29051540 Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy. Peanut allergy 230 European ancestry cases, 2,387 European ancestry controls 438 European ancestry cases, 2,510 European ancestry controls Illumina [5405832] (imputed) 1 peanut allergy measurement http://www.ebi.ac.uk/efo/EFO_0007017 GCST004980 Genome-wide genotyping array 2617 2017-11-20 29051540 Marenholz I 2017-10-20 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29051540 Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy. Hen's egg allergy 288 European ancestry cases, 2,387 European ancestry controls 416 European ancestry cases, 2,510 European ancestry controls Illumina [5405832] (imputed) 2 egg allergy measurement http://www.ebi.ac.uk/efo/EFO_0007018 GCST004977 Genome-wide genotyping array 2675 2017-11-28 29066090 Allen RJ 2017-10-20 Lancet Respir Med www.ncbi.nlm.nih.gov/pubmed/29066090 Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study. Idiopathic pulmonary fibrosis 602 European ancestry cases, 3,366 European ancestry controls 2,158 cases, 5,195 controls Affymetrix [NR] (imputed) 8 idiopathic pulmonary fibrosis http://www.ebi.ac.uk/efo/EFO_0000768 GCST004986 Genome-wide genotyping array 3968 2018-02-13 29374233 Lu AT 2018-01-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29374233 GWAS of epigenetic aging rates in blood reveals a critical role for TERT. Extrinsic epigenetic age acceleration 8,393 European ancestry individuals 1,023 African American individuals, 491 Hispanic individuals Affymetrix, Illumina [~ 7400000] (imputed) 3 aging http://purl.obolibrary.org/obo/GO_0007568 GCST005288 Genome-wide genotyping array 8393 2018-02-13 29374233 Lu AT 2018-01-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29374233 GWAS of epigenetic aging rates in blood reveals a critical role for TERT. Intrinsic epigenetic age acceleration 8,393 European ancestry individuals 1,023 African American individuals, 491 Hispanic individuals Affymetrix, Illumina [~ 7400000] (imputed) 6 aging http://purl.obolibrary.org/obo/GO_0007568 GCST005287 Genome-wide genotyping array 8393 2017-11-10 29088834 Kimura M 2017-08-24 Oncotarget www.ncbi.nlm.nih.gov/pubmed/29088834 A genome-wide association analysis identifies PDE1A|DNAJC10 locus on chromosome 2 associated with idiopathic pulmonary arterial hypertension in a Japanese population. Pulmonary arterial hypertension 23 Japanese ancestry cases, 2,002 Japanese ancestry controls 21 Japanese ancestry cases, 991 Japanese ancestry controls Illumina [1347690] 1 pulmonary arterial hypertension http://www.ebi.ac.uk/efo/EFO_0001361 GCST004947 Genome-wide genotyping array 2025 2017-12-18 29123153 Lee TH 2017-11-09 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29123153 A genome-wide association study links small-vessel ischemic stroke to autophagy. Small vessel stroke 342 Chinese ancestry cases, 1,731 Chinese ancestry control 188 Chinese ancestry cases, 1,265 Chinese ancestry control Affymetrix [552090] (imputed) 7 small vessel stroke http://www.ebi.ac.uk/efo/EFO_1001504 GCST005057 Genome-wide genotyping array 2073 2017-05-15 28046027 Kim T 2017-01-03 PLoS One www.ncbi.nlm.nih.gov/pubmed/28046027 Genome-Wide Association Study Reveals Four Loci for Lipid Ratios in the Korean Population and the Constitutional Subgroup. NHDL cholesterol to HDL cholesterol ratio 5,292 Korean ancestry individuals 2,567 Korean ancestry individuals Affymetrix [310746] 1 non-HDL cholesterol:HDL cholesterol ratio http://www.ebi.ac.uk/efo/EFO_0007931 GCST004035 Genome-wide genotyping array 5292 2017-05-15 28046027 Kim T 2017-01-03 PLoS One www.ncbi.nlm.nih.gov/pubmed/28046027 Genome-Wide Association Study Reveals Four Loci for Lipid Ratios in the Korean Population and the Constitutional Subgroup. LDL cholesterol to HDL cholesterol ratio 5,292 Korean ancestry individuals 2,567 Korean ancestry individuals Affymetrix [310746] 2 LDL cholesterol:HDL cholesterol ratio http://www.ebi.ac.uk/efo/EFO_0007930 GCST004036 Genome-wide genotyping array 5292 2017-05-15 28046027 Kim T 2017-01-03 PLoS One www.ncbi.nlm.nih.gov/pubmed/28046027 Genome-Wide Association Study Reveals Four Loci for Lipid Ratios in the Korean Population and the Constitutional Subgroup. Triglyceride to HDL cholesterol ratio 5,292 Korean ancestry individuals 2,567 Korean ancestry individuals Affymetrix [310746] 2 triglyceride:HDL cholesterol ratio http://www.ebi.ac.uk/efo/EFO_0007929 GCST004037 Genome-wide genotyping array 5292 2017-12-18 29077507 Chen H 2017-10-27 Am J Respir Cell Mol Biol www.ncbi.nlm.nih.gov/pubmed/29077507 Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men. Obstructive sleep apnea trait (apnea hypopnea index) 677 African American women, 544 African American men, 115 Asian women, 113 Asian men, 1,825 European ancestry women, 3,902 European ancestry men, 7,492 Hispanic women, 5,065 Hispanic men NA Affymetrix, Illumina [NR] (imputed) 31 sleep apnea measurement http://www.ebi.ac.uk/efo/EFO_0007817 GCST005051 Genome-wide genotyping array 19733 2017-12-18 29077507 Chen H 2017-10-27 Am J Respir Cell Mol Biol www.ncbi.nlm.nih.gov/pubmed/29077507 Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men. Obstructive sleep apnea during non-REM sleep (apnea hypopnea index) 1,221 African American individuals, 228 Asian individuals, 5,727 European ancestry individuals,12,557 Hispanic individuals 206 African American individuals, 2,792 Asian individuals, 5,315 European ancestry individuals, 55 European ancestry obstructive sleep apnea cases, 12 European ancestry controls Affymetrix, Illumina [NR] (imputed) 0 sleep apnea measurement during non-REM sleep http://www.ebi.ac.uk/efo/EFO_0008456 GCST005049 Genome-wide genotyping array 19733 2017-12-18 29077507 Chen H 2017-10-27 Am J Respir Cell Mol Biol www.ncbi.nlm.nih.gov/pubmed/29077507 Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men. Obstructive sleep apnea during REM sleep (apnea hypopnea index) 677 African American women, 544 African American men, 115 Asian women, 113 Asian men, 1,825 European ancestry women, 3,902 European ancestry men, 7,492 Hispanic women, 5,065 Hispanic men NA Affymetrix, Illumina [NR] (imputed) 7 sleep apnea measurement during REM sleep http://www.ebi.ac.uk/efo/EFO_0008455 GCST005050 Genome-wide genotyping array 19733 2018-08-17 29107063 Yashin AI 2017-10-26 Exp Gerontol www.ncbi.nlm.nih.gov/pubmed/29107063 Hidden heterogeneity in Alzheimer's disease: Insights from genetic association studies and other analyses. Alzheimer's disease at least 3,569 European, Black, and unknown ancestry cases, at least 19,085 European, Black, and unknown ancestry controls NA Illumina [up to 1329158] 1 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST006121 Genome-wide genotyping array 22654 2018-08-17 29107063 Yashin AI 2017-10-26 Exp Gerontol www.ncbi.nlm.nih.gov/pubmed/29107063 Hidden heterogeneity in Alzheimer's disease: Insights from genetic association studies and other analyses. Alzheimer's disease (age of onset) 12,169 European ancestry individuals, 2,078 Black individuals, 4,053 unknown ancestry individuals NA Illumina [up to 1329158] 1 Alzheimer's disease, age at onset http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0004847 GCST006120 Genome-wide genotyping array 18300 2017-12-05 29097388 Magvanjav O 2017-11-02 J Am Heart Assoc www.ncbi.nlm.nih.gov/pubmed/29097388 Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials. Uncontrolled blood pressure in combination therapy (beta blocker and thiazide diuretic) 123 European ancestry cases, 191 European ancestry controls 85 European ancestry cases, 136 European ancestry controls, 81 Hispanic cases, 112 Hispanic controls Illumina [NR] (imputed) 2 blood pressure, response to thiazide, response to beta blocker http://www.ebi.ac.uk/efo/EFO_0004325, http://www.ebi.ac.uk/efo/EFO_0007981, http://www.ebi.ac.uk/efo/EFO_0007766 GCST005039 Genome-wide genotyping array 314 2017-12-05 29097388 Magvanjav O 2017-11-02 J Am Heart Assoc www.ncbi.nlm.nih.gov/pubmed/29097388 Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials. Systolic blood pressure in combination therapy (beta blocker and thiazide diuretic) 314 European ancestry individuals 221 European ancestry individuals, 193 Hispanic individuals Illumina [NR] (imputed) 1 systolic blood pressure, response to thiazide, response to beta blocker http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0007981, http://www.ebi.ac.uk/efo/EFO_0007766 GCST005040 Genome-wide genotyping array 314 2017-12-05 29097388 Magvanjav O 2017-11-02 J Am Heart Assoc www.ncbi.nlm.nih.gov/pubmed/29097388 Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials. Diastolic blood pressure in combination therapy (beta blocker and thiazide diuretic) 314 European ancestry individuals 221 European ancestry individuals, 193 Hispanic individuals Illumina [NR] (imputed) 3 diastolic blood pressure, response to thiazide, response to beta blocker http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0007981, http://www.ebi.ac.uk/efo/EFO_0007766 GCST005041 Genome-wide genotyping array 314 2017-12-20 29127183 Seyerle AA 2017-11-10 Heart www.ncbi.nlm.nih.gov/pubmed/29127183 Genome-wide association study of PR interval in Hispanics/Latinos identifies novel locus at ID2. PR interval 14,756 Hispanic individuals 4,296 European ancestry individuals, 3,763 African American individuals, 6,805 East Asian ancestry individuals Affymetrix, Illumina [18828993] (imputed) 9 PR interval http://www.ebi.ac.uk/efo/EFO_0004462 GCST005080 Genome-wide genotyping array 14756 2018-09-05 29455858 Sung YJ 2018-02-15 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29455858 A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) 14,607 European ancestry current smokers, 65,935 European ancestry former and never smokers, 5,545 African ancestry current smokers, 21,571 African ancestry former and never smokers, 2,465 Asian ancestry current smokers, 10,973 Asian ancestry former and never smokers, 1,068 Hispanic current smokers, 7,737 Hispanic former and never smokers 48,198 European ancestry current smokers, 251,872 European ancestry former and never smokers, 1,971 African ancestry current smokers, 5,814 African ancestry former and never smokers, 29,485 Asian ancestry current smokers, 119,447 Asian ancestry former and never smokers, 3,737 Hispanic current smokers, 14,199 Hispanic former and never smokers Affymetrix, Illumina [18800000] (imputed) 9 smoking status measurement, systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006335 GCST006186 Genome-wide genotyping array 129901 2018-09-05 29455858 Sung YJ 2018-02-15 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29455858 A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) 14,607 European ancestry current smokers, 65,935 European ancestry former and never smokers, 5,545 African ancestry current smokers, 21,571 African ancestry former and never smokers, 2,465 Asian ancestry current smokers, 10,973 Asian ancestry former and never smokers, 1,068 Hispanic current smokers, 7,737 Hispanic former and never smokers 48,198 European ancestry current smokers, 251,872 European ancestry former and never smokers, 1,971 African ancestry current smokers, 5,814 African ancestry former and never smokers, 29,485 Asian ancestry current smokers, 119,447 Asian ancestry former and never smokers, 3,737 Hispanic current smokers, 14,199 Hispanic former and never smokers Affymetrix, Illumina [18800000] (imputed) 95 smoking status measurement, systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006335 GCST006195 Genome-wide genotyping array 129901 2018-09-05 29455858 Sung YJ 2018-02-15 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29455858 A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) 14,607 European ancestry current smokers, 65,935 European ancestry former and never smokers, 5,545 African ancestry current smokers, 21,571 African ancestry former and never smokers, 2,465 Asian ancestry current smokers, 10,973 Asian ancestry former and never smokers, 1,068 Hispanic current smokers, 7,737 Hispanic former and never smokers 48,198 European ancestry current smokers, 251,872 European ancestry former and never smokers, 1,971 African ancestry current smokers, 5,814 African ancestry former and never smokers, 29,485 Asian ancestry current smokers, 119,447 Asian ancestry former and never smokers, 3,737 Hispanic current smokers, 14,199 Hispanic former and never smokers Affymetrix, Illumina [18800000] (imputed) 9 smoking status measurement, diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336 GCST006194 Genome-wide genotyping array 129901 2018-09-05 29455858 Sung YJ 2018-02-15 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29455858 A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) 14,607 European ancestry current smokers, 65,935 European ancestry former and never smokers, 5,545 African ancestry current smokers, 21,571 African ancestry former and never smokers, 2,465 Asian ancestry current smokers, 10,973 Asian ancestry former and never smokers, 1,068 Hispanic current smokers, 7,737 Hispanic former and never smokers 48,198 European ancestry current smokers, 251,872 European ancestry former and never smokers, 1,971 African ancestry current smokers, 5,814 African ancestry former and never smokers, 29,485 Asian ancestry current smokers, 119,447 Asian ancestry former and never smokers, 3,737 Hispanic current smokers, 14,199 Hispanic former and never smokers Affymetrix, Illumina [18800000] (imputed) 97 smoking status measurement, diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336 GCST006193 Genome-wide genotyping array 129901 2018-09-05 29455858 Sung YJ 2018-02-15 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29455858 A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. Systolic blood pressure x smoking status (ever vs never) interaction (2df test) 43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers 139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers Affymetrix, Illumina [18800000] (imputed) 88 smoking status measurement, systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006335 GCST006192 Genome-wide genotyping array 128608 2018-09-05 29455858 Sung YJ 2018-02-15 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29455858 A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. Diastolic blood pressure x smoking status (ever vs never) interaction (1df test) 43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers 139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers Affymetrix, Illumina [18800000] (imputed) 2 smoking status measurement, diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336 GCST006191 Genome-wide genotyping array 128608 2018-09-05 29455858 Sung YJ 2018-02-15 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29455858 A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) 43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers 139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers Affymetrix, Illumina [18800000] (imputed) 91 smoking status measurement, diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336 GCST006190 Genome-wide genotyping array 128608 2018-09-05 29455858 Sung YJ 2018-02-15 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29455858 A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. Systolic blood pressure x smoking status (ever vs never) interaction (1df test) 43,016 European ancestry ever smokers, 37,535 European ancestry never smokers, 12,693 African ancestry ever smokers, 13,121 African ancestry never smokers, 4,142 Asian ancestry ever smokers, 9,296 Asian ancestry never smokers, 3,228 Hispanic ever smokers, 5,577 Hispanic never smokers 139,127 European ancestry ever smokers, 145,914 European ancestry never smokers, 3,105 African ancestry ever smokers, 3,075 African ancestry never smokers, 70,335 Asian ancestry ever smokers, 78,597 Asian ancestry never smokers, 6,810 Hispanic ever smokers, 11,133 Hispanic never smokers Affymetrix, Illumina [18800000] (imputed) 0 smoking status measurement, systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006335 GCST006189 Genome-wide genotyping array 128608 2018-09-05 29455858 Sung YJ 2018-02-15 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29455858 A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. Systolic blood pressure (cigarette smoking interaction) 80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals 305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals Affymetrix, Illumina [18800000] (imputed) 46 smoking status measurement, systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006335 GCST006188 Genome-wide genotyping array 129913 2018-09-05 29455858 Sung YJ 2018-02-15 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29455858 A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. Diastolic blood pressure (cigarette smoking interaction) 80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals 305,513 European ancestry individuals, 7,786 African individuals, 148,932 Asian individuals, 13,533 Hispanic individuals, 4,414 Brazilian individuals Affymetrix, Illumina [18800000] (imputed) 45 smoking status measurement, diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006336 GCST006187 Genome-wide genotyping array 129913 2018-07-24 26426971 Winkler TW 2015-10-01 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/26426971 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Body mass index x sex interaction up to 142,613 European ancestry men, up to 167,276 European ancestry women NA Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 0 sex interaction measurement, body mass index http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0004340 GCST005949 Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip] 309889 2018-07-24 26426971 Winkler TW 2015-10-01 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/26426971 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Body mass index x sex x age interaction (4df test) up to 51,625 European ancestry men aged <50, up to 60,654 European ancestry women aged <50, up to 90,988 European ancestry men aged >50, up to 106,622 European ancestry women aged >50 NA Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 15 sex interaction measurement, body mass index, age at assessment http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0008007 GCST005950 Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip] 310089 2018-07-24 26426971 Winkler TW 2015-10-01 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/26426971 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Body mass index up to 309,889 European ancestry individuals NA Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 200 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST005951 Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip] 309889 2018-07-24 26426971 Winkler TW 2015-10-01 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/26426971 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Body mass index (age>50) up to 90,988 European ancestry men, up to 106,622 European ancestry women NA Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 8 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST005952 Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip] 197610 2018-07-24 26426971 Winkler TW 2015-10-01 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/26426971 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Body mass index (age <50) up to 51,625 European ancestry men, up to 60,654 European ancestry women NA Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 11 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST005953 Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip] 112279 2018-07-24 26426971 Winkler TW 2015-10-01 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/26426971 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Body mass index x age interaction up to 112,279 European ancestry individuals aged <50, up to 197,610 European ancestry individuals aged >50 NA Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 5 body mass index, age at assessment http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0008007 GCST005954 Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip] 309989 2018-07-24 26426971 Winkler TW 2015-10-01 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/26426971 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Body mass index x sex x age interaction up to 51,625 European ancestry men aged <50, up to 60,654 European ancestry women aged <50, up to 90,988 European ancestry men aged >50, up to 106,622 European ancestry women aged >50 NA Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 0 sex interaction measurement, body mass index, age at assessment http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0008007 GCST005955 Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip] 310089 2018-07-24 26426971 Winkler TW 2015-10-01 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/26426971 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Waist-to-hip ratio adjusted for BMI up to 113,720 European ancestry men, up to 138,655 European ancestry women NA Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 85 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST005956 Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip] 252375 2018-07-24 26426971 Winkler TW 2015-10-01 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/26426971 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Waist-to-hip ratio adjusted for BMI (age <50) up to 43,776 European ancestry men, up to 50,526 European ancestry women NA Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 15 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST005957 Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip] 94302 2018-07-24 26426971 Winkler TW 2015-10-01 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/26426971 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Waist-to-hip ratio adjusted for BMI (age >50) up to 69,944 European ancestry men, up to 88,129 European ancestry women NA Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 20 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST005958 Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip] 158073 2018-07-24 26426971 Winkler TW 2015-10-01 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/26426971 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Waist-to-hip ratio adjusted for BMI x sex interaction up to 113,720 European ancestry men, up to 138,655 European ancestry women NA Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 33 BMI-adjusted waist-hip ratio, sex interaction measurement http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343 GCST005959 Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip] 252375 2018-07-24 26426971 Winkler TW 2015-10-01 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/26426971 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Waist-to-hip ratio adjusted for BMI x sex x age interaction up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50 NA Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 0 BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007 GCST005960 Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip] 252575 2018-07-24 26426971 Winkler TW 2015-10-01 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/26426971 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Waist-to-hip ratio adjusted for BMI x age interaction up to 94,302 European ancestry individuals aged <50, up to 158,073 European ancestry individuals aged >50 NA Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 0 BMI-adjusted waist-hip ratio, age at assessment http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008007 GCST005961 Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip] 252475 2018-07-24 26426971 Winkler TW 2015-10-01 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/26426971 The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) up to 43,776 European ancestry men aged <50, up to 50,526 European ancestry women aged <50, up to 69,944 European ancestry men aged >50, up to 88,129 European ancestry women aged >50 NA Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 85 BMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0008007 GCST005962 Genome-wide genotyping array, Targeted genotyping array [Metabochip, CardioMetabochip] 252575 2017-12-11 22885922 Morris AP 2012-09-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22885922 Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Type 2 diabetes 6,377 European ancestry male cases, 5,794 European ancestry female cases, 22,243 European ancestry male controls, 34,619 European ancestry female controls 12,938 European ancestry male cases, 8,553 European ancestry female cases, 904 Pakistani ancestry male cases, 274 Pakistani ancestry female cases, 30,273 European ancestry male controls, 25,374 European ancestry female controls, 2,088 Pakistani ancestry male controls, 384 Pakistani ancestry female controls Affymetrix, Illumina [up to 2500000] (imputed) 110 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST005047 Genome-wide genotyping array 69033 2017-06-02 28158719 Jain D 2017-02-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28158719 Genome-wide association of white blood cell counts in Hispanic/Latino Americans: the Hispanic Community Health Study/Study of Latinos. White blood cell count up to 11,809 Hispanic/Latino American individuals up to 7,200 Hispanic/Latino American individuals Illumina [27887661] (imputed) 5 leukocyte count http://www.ebi.ac.uk/efo/EFO_0004308 GCST004126 Genome-wide genotyping array 11809 2017-06-02 28158719 Jain D 2017-02-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28158719 Genome-wide association of white blood cell counts in Hispanic/Latino Americans: the Hispanic Community Health Study/Study of Latinos. White blood cell count (basophil) up to 11,809 Hispanic/Latino American individuals up to 7,200 Hispanic/Latino American individuals Illumina [27887661] (imputed) 5 basophil count http://www.ebi.ac.uk/efo/EFO_0005090 GCST004127 Genome-wide genotyping array 11809 2017-06-02 28158719 Jain D 2017-02-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28158719 Genome-wide association of white blood cell counts in Hispanic/Latino Americans: the Hispanic Community Health Study/Study of Latinos. White blood cell count (eosinophil) up to 11,809 Hispanic/Latino American individuals up to 7,200 Hispanic/Latino American individuals Illumina [27887661] (imputed) 5 eosinophil count http://www.ebi.ac.uk/efo/EFO_0004842 GCST004135 Genome-wide genotyping array 11809 2017-06-02 28158719 Jain D 2017-02-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28158719 Genome-wide association of white blood cell counts in Hispanic/Latino Americans: the Hispanic Community Health Study/Study of Latinos. White blood cell count (lymphocyte) up to 11,809 Hispanic/Latino American individuals up to 7,200 Hispanic/Latino American individuals Illumina [27887661] (imputed) 2 lymphocyte count http://www.ebi.ac.uk/efo/EFO_0004587 GCST004130 Genome-wide genotyping array 11809 2017-06-02 28158719 Jain D 2017-02-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28158719 Genome-wide association of white blood cell counts in Hispanic/Latino Americans: the Hispanic Community Health Study/Study of Latinos. White blood cell count (monocyte) up to 11,809 Hispanic/Latino American individuals up to 7,200 Hispanic/Latino American individuals Illumina [27887661] (imputed) 9 monocyte count http://www.ebi.ac.uk/efo/EFO_0005091 GCST004129 Genome-wide genotyping array 11809 2017-06-02 28158719 Jain D 2017-02-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28158719 Genome-wide association of white blood cell counts in Hispanic/Latino Americans: the Hispanic Community Health Study/Study of Latinos. White blood cell count (neutrophil) up to 11,809 Hispanic/Latino American individuals up to 7,200 Hispanic/Latino American individuals Illumina [27887661] (imputed) 4 neutrophil count http://www.ebi.ac.uk/efo/EFO_0004833 GCST004128 Genome-wide genotyping array 11809 2017-08-03 28485404 Jorgenson E 2017-05-09 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/28485404 Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study. Alcohol consumption (drinks per week) 23,104 European ancestry non-drinker individuals, 47,967 European ancestry drinker individuals, 2,673 Hispanic/Latino non-drinker individuals, 4,374 Hispanic/Latino drinker individuals, 3,288 East Asian ancestry non-drinker individuals, 2,746 East Asian ancestry drinker individuals, 1,165 African American non-drinkers individuals, 1,310 African American drinker individuals.        NA Affymetrix [NR] (imputed) 8 alcohol consumption measurement, alcohol drinking http://www.ebi.ac.uk/efo/EFO_0007878, http://www.ebi.ac.uk/efo/EFO_0004329 GCST004405 Genome-wide genotyping array 86627 2017-08-03 28485404 Jorgenson E 2017-05-09 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/28485404 Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study. Alcohol consumption (drinkers vs non-drinkers) 23,104 European ancestry non-drinker individuals, 47,967 European ancestry drinker individuals, 2,673 Hispanic/Latino non-drinker individuals, 4,374 Hispanic/Latino drinker individuals, 3,288 East Asian ancestry non-drinker individuals, 2,746 East Asian ancestry drinker individuals, 1,165 African American non-drinkers individuals, 1,310 African American drinker individuals.        NA Affymetrix [NR] (imputed) 7 alcohol consumption measurement, alcohol drinking http://www.ebi.ac.uk/efo/EFO_0007878, http://www.ebi.ac.uk/efo/EFO_0004329 GCST004404 Genome-wide genotyping array 86627 2017-07-13 28471803 Choe EK 2017-05-03 Eur J Cancer Prev www.ncbi.nlm.nih.gov/pubmed/28471803 Search for genetic factor association with cancer-free prostate-specific antigen level elevation on the basis of a genome-wide association study in the Korean population. Elevated serum prostate-specific antigen levels in healthy men 2,841 Korean ancestry individuals 1,283 Korean ancestry individuals Affymetrix [584061] 2 prostate specific antigen measurement http://www.ebi.ac.uk/efo/EFO_0004624 GCST004345 Genome-wide genotyping array 2841 2017-08-16 28540026 Anney RJL 2017-05-22 Mol Autism www.ncbi.nlm.nih.gov/pubmed/28540026 Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia. Autism spectrum disorder or schizophrenia schizophrenia cases and controls (see Ripke, 2014), up to 6,197 European ancestry ASD cases, up to 7,377 European ancestry controls, up to 1,190 ASD cases, up to 1,190 controls NA Affymetrix, Illumina [NR] 301 schizophrenia, autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0003756 GCST004521 Genome-wide genotyping array 17968 2017-08-16 28540026 Anney RJL 2017-05-22 Mol Autism www.ncbi.nlm.nih.gov/pubmed/28540026 Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia. Autism spectrum disorder 6,197 European ancestry cases, 7,377 European ancestry controls, 1,190 cases, 1,190 controls 8,266 European ancestry cases, 147,562 European ancestry controls, 886 cases, 1,105 controls Affymetrix, Illumina [6695386] (imputed) 3 autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0003756 GCST004520 Genome-wide genotyping array 15954 2017-08-10 28443625 Justice AE 2017-04-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28443625 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. BMI (smoking interaction) 98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men 21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 2 smoking behavior, body mass index http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340 GCST004496 Genome-wide genotyping array 196760 2017-08-10 28443625 Justice AE 2017-04-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28443625 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Waist circumference adjusted for BMI (adjusted for smoking behaviour) 97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men 21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 140 smoking behavior, BMI-adjusted waist circumference http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789 GCST004500 Genome-wide genotyping array 195506 2017-08-10 28443625 Justice AE 2017-04-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28443625 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) 95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men 21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 116 smoking behavior, BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788 GCST004505 Genome-wide genotyping array 191661 2017-08-10 28443625 Justice AE 2017-04-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28443625 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Waist-to-hip ratio adjusted for BMI (smoking interaction) 95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men 21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 2 smoking behavior, BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788 GCST004506 Genome-wide genotyping array 191661 2017-08-10 28443625 Justice AE 2017-04-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28443625 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Waist circumference adjusted for BMI (smoking interaction) 97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men 21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 2 smoking behavior, BMI-adjusted waist circumference http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789 GCST004502 Genome-wide genotyping array 195506 2017-08-10 28443625 Justice AE 2017-04-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28443625 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) 97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men 21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 135 smoking behavior, BMI-adjusted waist circumference http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007789 GCST004501 Genome-wide genotyping array 195506 2017-08-10 28443625 Justice AE 2017-04-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28443625 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) 95,362 European ancestry women, 62,085 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men 21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 45 smoking behavior, BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007788 GCST004507 Genome-wide genotyping array 191661 2017-08-10 28443625 Justice AE 2017-04-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28443625 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. BMI (adjusted for smoking behaviour) 98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men 21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 145 smoking behavior, body mass index http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340 GCST004495 Genome-wide genotyping array 196760 2017-08-10 28443625 Justice AE 2017-04-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28443625 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Body mass index (joint analysis main effects and smoking interaction) 98,173 European ancestry women, 64,373 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men 21,496 European ancestry women, 24,385 European ancestry men, 118,364 European ancestry individuals, 2,326 African American/Afro-Caribbean ancestry women, 855 African American/Afro-Caribbean ancestry men Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 140 smoking behavior, body mass index http://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0004340 GCST004497 Genome-wide genotyping array 196760 2017-08-10 28443625 Justice AE 2017-04-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28443625 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Waist circumference adjusted for BMI in non-smokers 77,113 European ancestry women, 47,319 European ancestry men, 4,856 European ancestry individuals, 8,799 African American/Afro-Caribbean ancestry women, 1,803 African American/Afro-Caribbean ancestry men, 1,020 Indian Asian ancestry women, 6,691 Indian Asian ancestry men, 1,526 Filipino ancestry women, 2,469 Hispanic/Latino ancestry women, 1,318 Hispanic/Latino ancestry men 16,011 European ancestry women, 17,912 European ancestry men, 105,218 European ancestry individuals, 2,073 African American/Afro-Caribbean ancestry women, 647 African American/Afro-Caribbean ancestry men Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 108 BMI-adjusted waist circumference http://www.ebi.ac.uk/efo/EFO_0007789 GCST004504 Genome-wide genotyping array 152914 2017-08-10 28443625 Justice AE 2017-04-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28443625 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Waist-to-hip ratio adjusted for BMI in smokers 18,972 European ancestry women, 16,109 European ancestry men, 973 European ancestry individuals, 1,701 African American/Afro-Caribbean ancestry women, 903 African American/Afro-Caribbean ancestry men, 10 Indian Asian ancestry women, 957 Indian Asian ancestry men, 267 Filipino ancestry women, 475 Hispanic/Latino ancestry women, 446 Hispanic/Latino ancestry men 5,485 European ancestry women, 6,471 European ancestry men, 13,416 European ancestry individuals, 253 African American/Afro-Caribbean ancestry women, 208 African American/Afro-Caribbean ancestry men Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 1 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST004509 Genome-wide genotyping array 40813 2017-08-10 28443625 Justice AE 2017-04-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28443625 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. BMI in non-smokers 77,279 European ancestry women, 47,280 European ancestry men, 4,856 European ancestry individuals, 8,799 African American/Afro-Caribbean ancestry women, 1,803 African American/Afro-Caribbean ancestry men, 1,020 Indian Asian ancestry women, 6,691 Indian Asian ancestry men, 1,526 Filipino ancestry women, 2,469 Hispanic/Latino ancestry women, 1,318 Hispanic/Latino ancestry men 16,011 European ancestry women, 17,912 European ancestry men, 105,218 European ancestry individuals, 2,073 African American/Afro-Caribbean ancestry women, 647 African American/Afro-Caribbean ancestry men Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 105 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST004499 Genome-wide genotyping array 153041 2017-08-10 28443625 Justice AE 2017-04-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28443625 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Waist circumference adjusted for BMI in smokers 19,276 European ancestry women, 16,408 European ancestry men, 973 European ancestry individuals, 1,701 African American/Afro-Caribbean ancestry women, 903 African American/Afro-Caribbean ancestry men, 10 Indian Asian ancestry women, 957 Indian Asian ancestry men, 267 Filipino ancestry women, 475 Hispanic/Latino ancestry women, 446 Hispanic/Latino ancestry men 5,485 European ancestry women, 6,471 European ancestry men, 13,416 European ancestry individuals, 253 African American/Afro-Caribbean ancestry women, 208 African American/Afro-Caribbean ancestry men Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 15 BMI-adjusted waist circumference http://www.ebi.ac.uk/efo/EFO_0007789 GCST004503 Genome-wide genotyping array 41416 2017-08-10 28443625 Justice AE 2017-04-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28443625 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. BMI in smokers 19,883 European ancestry women, up to 16,928 European ancestry men, up to 973 European ancestry individuals, 1,701 African American/Afro-Caribbean ancestry women, 903 African American/Afro-Caribbean ancestry men, 10 Indian Asian ancestry women, 957 Indian Asian ancestry men, 267 Filipino ancestry women, 475 Hispanic/Latino ancestry women, 446 Hispanic/Latino ancestry men 5,485 European ancestry women, 6,471 European ancestry men, 13,416 European ancestry individuals, 253 African American/Afro-Caribbean ancestry women, 208 African American/Afro-Caribbean ancestry men Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 30 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST004498 Genome-wide genotyping array 42543 2017-08-10 28443625 Justice AE 2017-04-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28443625 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Waist-to-hip ratio adjusted for BMI in non-smokers 75,379 European ancestry women, 45,811 European ancestry men, 4,856 European ancestry individuals, 8,799 African American/Afro-Caribbean ancestry women, 1,803 African American/Afro-Caribbean ancestry men, 1,020 Indian Asian ancestry women, 6,691 Indian Asian ancestry men, 1,526 Filipino ancestry women, 2,469 Hispanic/Latino ancestry women, 1,318 Hispanic/Latino ancestry men 16,011 European ancestry women, 17,912 European ancestry men, 105,218 European ancestry individuals, 2,073 African American/Afro-Caribbean ancestry women, 647 African American/Afro-Caribbean ancestry men Affymetrix, Illumina, Perlegen [up to 2800000] (imputed) 46 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST004508 Genome-wide genotyping array 149672 2017-06-21 28314753 Terao C 2017-03-17 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/28314753 Transethnic meta-analysis identifies GSDMA and PRDM1 as susceptibility genes to systemic sclerosis. Systemic sclerosis 700 Japanese ancestry cases, 1,797 Japanese ancestry controls, 564 European ancestry cases, 1,776 European ancestry controls 564 Japanese ancestry cases, 1,863 Japanese ancestry controls, 2,592 European ancestry cases, 9,315 European ancestry controls Illumina [3610917] (imputed) 7 systemic scleroderma http://www.ebi.ac.uk/efo/EFO_0000717 GCST004202 Genome-wide genotyping array 4837 2017-07-24 28498854 Liang J 2017-05-12 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28498854 Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations. Systolic blood pressure Up to 31,155 African individuals Up to 4,187 African individuals, up to 14,016 Korean ancestry individuals, up to 23,914 European ancestry individuals, up to 12,278 Hispanic individuals Affymetrix, Illumina [at least 30072738] (imputed) 9 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST004385 Genome-wide genotyping array 31155 2017-07-24 28498854 Liang J 2017-05-12 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28498854 Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations. Diastolic blood pressure Up to 31,155 African individuals Up to 4,187 African individuals, up to 14,016 Korean ancestry individuals, up to 23,914 European ancestry individuals, up to 12,278 Hispanic individuals Affymetrix, Illumina [at least 30072738] (imputed) 15 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST004386 Genome-wide genotyping array 31155 2017-07-24 28498854 Liang J 2017-05-12 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28498854 Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations. Pulse pressure Up to 31,155 African individuals Up to 4,187 African individuals, up to 14,016 Korean ancestry individuals, up to 23,914 European ancestry individuals, up to 12,278 Hispanic individuals Affymetrix, Illumina [at least 30072738] (imputed) 9 pulse pressure measurement http://www.ebi.ac.uk/efo/EFO_0005763 GCST004387 Genome-wide genotyping array 31155 2017-07-24 28498854 Liang J 2017-05-12 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28498854 Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations. Hypertension 18,440 African individuals 2,375 African individuals, 3,718 Korean ancestry individuals, 9,348 European ancestry individuals, 3,445 Hispanic individuals Affymetrix, Illumina [at least 30072738] (imputed) 7 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST004384 Genome-wide genotyping array 18440 2017-07-24 28498854 Liang J 2017-05-12 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28498854 Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations. Blood pressure traits (multi-trait analysis) Up to 31,155 African individuals Up to 4,187 African individuals, up to 14,016 Korean ancestry individuals, up to 23,914 European ancestry individuals, up to 12,278 Hispanic individuals Affymetrix, Illumina [at least 30072738] (imputed) 32 pulse pressure measurement, diastolic blood pressure, systolic blood pressure, hypertension http://www.ebi.ac.uk/efo/EFO_0005763, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0000537 GCST004388 Genome-wide genotyping array 31155 2017-09-29 28820441 Veenstra J 2017-08-19 Nutrients www.ncbi.nlm.nih.gov/pubmed/28820441 Genome-Wide Interaction Study of Omega-3 PUFAs and Other Fatty Acids on Inflammatory Biomarkers of Cardiovascular Health in the Framingham Heart Study. Interleukin-6 (red blood cell fatty acid level interaction) 2,703 individuals NA Affymetrix [2500000] (imputed) 2 fatty acid measurement, interleukin-6 measurement http://www.ebi.ac.uk/efo/EFO_0005110, http://www.ebi.ac.uk/efo/EFO_0004810 GCST004814 Genome-wide genotyping array 2703 2017-09-29 28820441 Veenstra J 2017-08-19 Nutrients www.ncbi.nlm.nih.gov/pubmed/28820441 Genome-Wide Interaction Study of Omega-3 PUFAs and Other Fatty Acids on Inflammatory Biomarkers of Cardiovascular Health in the Framingham Heart Study. Lipoprotein-associated phospholipase A2 (red blood cell fatty acid level interaction) 2,703 individuals NA Affymetrix [2500000] (imputed) 0 fatty acid measurement, lipoprotein-associated phospholipase A(2) measurement http://www.ebi.ac.uk/efo/EFO_0005110, http://www.ebi.ac.uk/efo/EFO_0004746 GCST004816 Genome-wide genotyping array 2703 2017-09-29 28820441 Veenstra J 2017-08-19 Nutrients www.ncbi.nlm.nih.gov/pubmed/28820441 Genome-Wide Interaction Study of Omega-3 PUFAs and Other Fatty Acids on Inflammatory Biomarkers of Cardiovascular Health in the Framingham Heart Study. Intercellular adhesion molecule 1 (red blood cell fatty acid level interaction) 2,703 individuals NA Affymetrix [2500000] (imputed) 1 fatty acid measurement, ICAM-1 measurement http://www.ebi.ac.uk/efo/EFO_0005110, http://www.ebi.ac.uk/efo/EFO_0004520 GCST004818 Genome-wide genotyping array 2703 2017-09-29 28820441 Veenstra J 2017-08-19 Nutrients www.ncbi.nlm.nih.gov/pubmed/28820441 Genome-Wide Interaction Study of Omega-3 PUFAs and Other Fatty Acids on Inflammatory Biomarkers of Cardiovascular Health in the Framingham Heart Study. Cellular adhesion molecule (red blood cell fatty acid level interaction) 2,703 individuals NA Affymetrix [2500000] (imputed) 1 fatty acid measurement, cellular adhesion molecule measurement http://www.ebi.ac.uk/efo/EFO_0005110, http://www.ebi.ac.uk/efo/EFO_0008353 GCST004820 Genome-wide genotyping array 2703 2017-09-29 28820441 Veenstra J 2017-08-19 Nutrients www.ncbi.nlm.nih.gov/pubmed/28820441 Genome-Wide Interaction Study of Omega-3 PUFAs and Other Fatty Acids on Inflammatory Biomarkers of Cardiovascular Health in the Framingham Heart Study. Monocyte chemoattractant protein-1 (red blood cell fatty acid level interaction) 2,703 individuals NA Affymetrix [2500000] (imputed) 1 fatty acid measurement, CCL2 measurement http://www.ebi.ac.uk/efo/EFO_0005110, http://www.ebi.ac.uk/efo/EFO_0004749 GCST004821 Genome-wide genotyping array 2703 2017-09-29 28820441 Veenstra J 2017-08-19 Nutrients www.ncbi.nlm.nih.gov/pubmed/28820441 Genome-Wide Interaction Study of Omega-3 PUFAs and Other Fatty Acids on Inflammatory Biomarkers of Cardiovascular Health in the Framingham Heart Study. Tumor necrosis factor receptor II (red blood cell fatty acid level interaction) 2,703 individuals NA Affymetrix [2500000] (imputed) 1 fatty acid measurement, tumor necrosis factor receptor II measurement http://www.ebi.ac.uk/efo/EFO_0005110, http://www.ebi.ac.uk/efo/EFO_0008384 GCST004817 Genome-wide genotyping array 2703 2017-09-29 28820441 Veenstra J 2017-08-19 Nutrients www.ncbi.nlm.nih.gov/pubmed/28820441 Genome-Wide Interaction Study of Omega-3 PUFAs and Other Fatty Acids on Inflammatory Biomarkers of Cardiovascular Health in the Framingham Heart Study. C-reactive protein (red blood cell fatty acid level interaction) 2,703 individuals NA Affymetrix [2500000] (imputed) 2 fatty acid measurement, C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0005110, http://www.ebi.ac.uk/efo/EFO_0004458 GCST004815 Genome-wide genotyping array 2703 2017-09-29 28820441 Veenstra J 2017-08-19 Nutrients www.ncbi.nlm.nih.gov/pubmed/28820441 Genome-Wide Interaction Study of Omega-3 PUFAs and Other Fatty Acids on Inflammatory Biomarkers of Cardiovascular Health in the Framingham Heart Study. Osteoprotegerin (red blood cell fatty acid level interaction) 2,703 individuals NA Affymetrix [2500000] (imputed) 0 fatty acid measurement, osteoprotegerin measurement http://www.ebi.ac.uk/efo/EFO_0005110, http://www.ebi.ac.uk/efo/EFO_0005918 GCST004819 Genome-wide genotyping array 2703 2017-09-29 28820441 Veenstra J 2017-08-19 Nutrients www.ncbi.nlm.nih.gov/pubmed/28820441 Genome-Wide Interaction Study of Omega-3 PUFAs and Other Fatty Acids on Inflammatory Biomarkers of Cardiovascular Health in the Framingham Heart Study. P-Selectin (red blood cell fatty acid level interaction) 2,703 individuals NA Affymetrix [2500000] (imputed) 0 fatty acid measurement, P-Selectin measurement http://www.ebi.ac.uk/efo/EFO_0005110, http://www.ebi.ac.uk/efo/EFO_0008254 GCST004822 Genome-wide genotyping array 2703 2017-09-23 28828242 Dajani R 2017-08-17 PeerJ www.ncbi.nlm.nih.gov/pubmed/28828242 Genome-wide association study identifies novel type II diabetes risk loci in Jordan subpopulations. Type 2 diabetes 67 Greater Middle Eastern ancestry cases, 214 Greater Middle Eastern ancestry controls 1,952 European ancestry cases, 2,960 European ancestry controls Illumina [645000] 1 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST004782 Genome-wide genotyping array 281 2018-05-30 29203360 Sanders MGH 2017-12-02 J Invest Dermatol www.ncbi.nlm.nih.gov/pubmed/29203360 The genetics of seborrheic dermatitis: a candidate gene approach and pilot genome-wide association study. Seborrheic dermatitis 609 European and unknown ancestry cases, 3441 European and unknown ancestry controls NA Illumina [9008729] (imputed) 12 seborrheic dermatitis http://www.ebi.ac.uk/efo/EFO_1000764 GCST005655 Genome-wide genotyping array 4050 2017-08-18 28537267 Sapkota Y 2017-05-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28537267 Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism. Endometriosis 14,926 European ancestry cases, 189,715 European ancestry controls, 2,119 Japanese ancestry cases, 2,143 Japanese ancestry controls NA Affymetrix, Illumina [up to 6979035] (imputed) 35 endometriosis http://www.ebi.ac.uk/efo/EFO_0001065 GCST004549 Genome-wide genotyping array 208903 2017-07-18 28530673 Sniekers S 2017-05-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28530673 Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence. Intelligence up to 58,799 European ancestry adults, up to 19,509 European ancestry children NA Affymetrix, Illumina [12104294] (imputed) 36 intelligence http://www.ebi.ac.uk/efo/EFO_0004337 GCST004364 Genome-wide genotyping array 78308 2017-07-13 28421636 Dennis J 2017-04-18 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/28421636 Leveraging cell type specific regulatory regions to detect SNPs associated with tissue factor pathway inhibitor plasma levels. Tissue factor pathway inhibitor levels 251 French Canadian individuals from 5 families 1,033 European ancestry individuals Illumina [6159088] (imputed) 0 tissue factor pathway inhibitor measurement http://www.ebi.ac.uk/efo/EFO_0007968 GCST004344 Genome-wide genotyping array 256 2017-08-14 28430825 Ng MCY 2017-04-21 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28430825 Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium. Waist-to-hip ratio adjusted for body mass index 4,783 African American men, 15,601 African American women 981 African American men, 1,730 African American women, 104,079 European ancestry men, 116,742 European ancestry women Affymetrix, Illumina [20502658] (imputed) 13 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST004518 Genome-wide genotyping array 20384 2017-08-14 28430825 Ng MCY 2017-04-21 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28430825 Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium. Body mass index (adult) 16,559 African ancestry men, 26,193 African ancestry women 2,458 African ancestry men, 7,685 African ancestry women, 152,893 European ancestry men, 171,977 European ancestry women Affymetrix, Illumina [17972087] (imputed) 32 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST004519 Genome-wide genotyping array 42752 2018-04-26 26051272 Fischer A 2015-09-15 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/26051272 Identification of Immune-Relevant Factors Conferring Sarcoidosis Genetic Risk. Sarcoidosis 1,726 European ancestry cases, 5,482 European ancestry controls 1,912 European ancestry cases, 5,938 European ancestry controls, 781 African American cases, 876 African American controls Illumina [128705] 9 Sarcoidosis http://www.orpha.net/ORDO/Orphanet_797 GCST005538 Targeted genotyping array [ImmunoChip] 7208 2018-01-15 29160300 Oetting WS 2017-11-21 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/29160300 Genome-wide association study identifies the common variants in CYP3A4 and CYP3A5 responsible for variation in tacrolimus trough concentration in Caucasian kidney transplant recipients. Tacrolimus trough concentration in kidney transplant patients 1,345 European ancestry individuals (homozygous for LoF CYPA3A5) NA Affymetrix [1221308] (imputed) 1 tacrolimus measurement http://www.ebi.ac.uk/efo/EFO_0008458 GCST005144 Genome-wide genotyping array 1353 2017-07-13 28537254 Tsoi LC 2017-05-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28537254 Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants. Psoriasis Up to 11,988 European ancestry cases, up to 275,335 European ancestry controls 7,044 European ancestry cases, 11,434 European ancestry controls Illumina, Perlegen [9113515] (imputed) 61 psoriasis http://www.ebi.ac.uk/efo/EFO_0000676 GCST004346 Genome-wide genotyping array 287323 2017-08-16 28476931 Piaggi P 2017-05-05 Diabetes www.ncbi.nlm.nih.gov/pubmed/28476931 A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated With Reduced Energy Expenditure in American Indians. Energy expenditure (24h) 419 Pima Indian ancestry individuals NA Affymetrix [491265] 9 energy expenditure measurement http://www.ebi.ac.uk/efo/EFO_0008005 GCST004524 Genome-wide genotyping array 419 2017-08-16 28476931 Piaggi P 2017-05-05 Diabetes www.ncbi.nlm.nih.gov/pubmed/28476931 A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated With Reduced Energy Expenditure in American Indians. Resting metabolic rate 509 Pima Indian ancestry individuals NA Affymetrix [491265] 10 resting metabolic rate measurement http://www.ebi.ac.uk/efo/EFO_0008004 GCST004523 Genome-wide genotyping array 509 2017-07-18 28492228 Parks T 2017-05-11 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28492228 Association between a common immunoglobulin heavy chain allele and rheumatic heart disease risk in Oceania. Rheumatic heart disease 767 Oceanian ancestry cases, 1,462 Oceanian ancestry controls, 168 Fijian Indian cases, 151 Fijian Indian controls, 71 mixed and other ancestry cases, 236 mixed and other ancestry controls NA Illumina [5356509] (imputed) 2 rheumatic heart disease http://www.ebi.ac.uk/efo/EFO_1001161 GCST004366 Genome-wide genotyping array 2855 2017-07-19 28494655 Duncan L 2017-05-12 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/28494655 Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa. Anorexia nervosa 3,495 European ancestry cases, 10,982 European ancestry controls NA Illumina [10641224] (imputed) 6 anorexia nervosa http://www.ebi.ac.uk/efo/EFO_0004215 GCST004367 Genome-wide genotyping array 14477 2017-08-10 28490609 Wood AR 2017-05-10 Diabetes www.ncbi.nlm.nih.gov/pubmed/28490609 A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants. Peak insulin response 2,337 Hispanic individuals, 2,159 European ancestry individuals, 332 Pima Indian ancestry individuals 739 European ancestry individuals Affymetrix, Illumina [~ 39000000] (imputed) 9 peak insulin response measurement http://www.ebi.ac.uk/efo/EFO_0008000 GCST004487 Genome-wide genotyping array 4828 2017-08-21 28490609 Wood AR 2017-05-10 Diabetes www.ncbi.nlm.nih.gov/pubmed/28490609 A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants. Acute insulin response 2,346 Hispanic individuals, 2,087 European ancestry individuals, 332 Pima Indian ancestry individuals 741 European ancestry individuals Affymetrix, Illumina [~ 39000000] (imputed) 8 acute insulin response measurement http://www.ebi.ac.uk/efo/EFO_0006831 GCST004575 Genome-wide genotyping array 4765 2017-08-10 28490609 Wood AR 2017-05-10 Diabetes www.ncbi.nlm.nih.gov/pubmed/28490609 A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants. Insulin secretion rate 527 European ancestry individuals NA Affymetrix, Illumina [~ 39000000] (imputed) 2 insulin secretion measurement http://www.ebi.ac.uk/efo/EFO_0008001 GCST004488 Genome-wide genotyping array 527 2017-08-10 28490609 Wood AR 2017-05-10 Diabetes www.ncbi.nlm.nih.gov/pubmed/28490609 A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants. Insulin disposition index 2,345 Hispanic individuals, 2,042 European ancestry individuals, 332 Pima Indian ancestry individuals 741 European ancestry individuals Affymetrix, Illumina [~ 39000000] (imputed) 1 disposition index measurement http://www.ebi.ac.uk/efo/EFO_0006832 GCST004489 Genome-wide genotyping array 4719 2018-12-06 28490609 Wood AR 2017-05-10 Diabetes www.ncbi.nlm.nih.gov/pubmed/28490609 A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants. Insulin disposition index (BMI adjusted) 2,345 Hispanic individuals, 2,042 European ancestry individuals, 332 Pima Indian ancestry individuals 741 European ancestry individuals Affymetrix, Illumina [~ 39000000] (imputed) 0 disposition index measurement http://www.ebi.ac.uk/efo/EFO_0006832 GCST006681 Genome-wide genotyping array 4719 2018-12-06 28490609 Wood AR 2017-05-10 Diabetes www.ncbi.nlm.nih.gov/pubmed/28490609 A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants. Peak insulin response (BMI and insulin secretion adjusted) 2,337 Hispanic individuals, 2,159 European ancestry individuals, 332 Pima Indian ancestry individuals 739 European ancestry individuals Affymetrix, Illumina [~ 39000000] (imputed) 1 peak insulin response measurement http://www.ebi.ac.uk/efo/EFO_0008000 GCST006675 Genome-wide genotyping array 4828 2018-12-06 28490609 Wood AR 2017-05-10 Diabetes www.ncbi.nlm.nih.gov/pubmed/28490609 A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants. Peak insulin response (insulin secretion adjusted) 2,337 Hispanic individuals, 2,159 European ancestry individuals, 332 Pima Indian ancestry individuals 739 European ancestry individuals Affymetrix, Illumina [~ 39000000] (imputed) 1 peak insulin response measurement http://www.ebi.ac.uk/efo/EFO_0008000 GCST006676 Genome-wide genotyping array 4828 2018-12-06 28490609 Wood AR 2017-05-10 Diabetes www.ncbi.nlm.nih.gov/pubmed/28490609 A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants. Acute insulin response (insulin secretion and BMI adjusted) 2,346 Hispanic individuals, 2,087 European ancestry individuals, 332 Pima Indian ancestry individuals 741 European ancestry individuals Affymetrix, Illumina [~ 39000000] (imputed) 0 acute insulin response measurement http://www.ebi.ac.uk/efo/EFO_0006831 GCST006678 Genome-wide genotyping array 4765 2018-12-06 28490609 Wood AR 2017-05-10 Diabetes www.ncbi.nlm.nih.gov/pubmed/28490609 A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants. Acute insulin response (insulin secretion adjusted) 2,346 Hispanic individuals, 2,087 European ancestry individuals, 332 Pima Indian ancestry individuals 741 European ancestry individuals Affymetrix, Illumina [~ 39000000] (imputed) 1 acute insulin response measurement http://www.ebi.ac.uk/efo/EFO_0006831 GCST006677 Genome-wide genotyping array 4765 2018-12-06 28490609 Wood AR 2017-05-10 Diabetes www.ncbi.nlm.nih.gov/pubmed/28490609 A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants. insulin secretion rate (BMI adjusted) 527 European ancestry individuals NA Affymetrix, Illumina [~ 39000000] (imputed) 0 insulin secretion measurement http://www.ebi.ac.uk/efo/EFO_0008001 GCST006679 Genome-wide genotyping array 527 2017-07-14 28472463 Mullin BH 2017-05-04 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28472463 Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation. Bone ultrasound measurement (velocity of sound) 1,268 whole genome sequenced European ancestry women, 8,880 European ancestry women, 6,479 European ancestry men NA Illumina [11973598] (imputed) 21 bone quantitative ultrasound measurement http://www.ebi.ac.uk/efo/EFO_0004514 GCST004350 Genome-wide genotyping array 16627 2017-07-14 28472463 Mullin BH 2017-05-04 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28472463 Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation. Bone ultrasound measurement (broadband ultrasound attenuation) 1,268 whole genome sequenced European ancestry women, 8,880 European ancestry women, 6,479 European ancestry men NA Illumina [11973598] (imputed) 28 bone quantitative ultrasound measurement http://www.ebi.ac.uk/efo/EFO_0004514 GCST004351 Genome-wide genotyping array 16627 2017-08-30 28495826 Williams SR 2017-06-01 Stroke www.ncbi.nlm.nih.gov/pubmed/28495826 Genetic Drivers of von Willebrand Factor Levels in an Ischemic Stroke Population and Association With Risk for Recurrent Stroke. vWF levels in ischaemic stroke and hyperhomocysteinaemia 1,931 European and unknown ancestry individuals NA NR [NR] (imputed) 3 von Willebrand factor measurement http://www.ebi.ac.uk/efo/EFO_0004629 GCST004598 Genome-wide genotyping array 1931 2018-12-06 23603763 Liu JZ 2013-06-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23603763 Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis. Primary sclerosing cholangitis 3,789 European ancestry cases, 25,079 European ancestry controls NA Illumina [140322] (imputed) 19 sclerosing cholangitis http://www.ebi.ac.uk/efo/EFO_0004268 GCST006670 Targeted genotyping array [ImmunoChip] 28868 2018-05-04 23603763 Liu JZ 2013-06-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23603763 Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis. Primary sclerosing cholangitis associated immune-mediated diseases (Crohn's disease, celiac disease, psoriasis, rheumatoid arthritis, sarcoidosis, type 1 diabetes or ulcerative colitis) (pleiotropy) 6,333 European ancestry Crohn's disease cases, 4,533 European ancestry celiac disease cases, 2,529 European ancestry psoriasis cases, 5,539 European ancestry rheumatoid arthritis cases, 568 European ancestry sarcoidosis cases, 7,514 European ancestry type I diabetes cases, 6,687 European ancestry ulcerative colitis cases, 3,789 European ancestry sclerosing cholangitis cases, 106,357 European ancestry controls NA Illumina [at least 130422] 0 rheumatoid arthritis, type I diabetes mellitus, psoriasis, Sarcoidosis, celiac disease, ulcerative colitis, Crohn's disease, sclerosing cholangitis http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0001359, http://www.ebi.ac.uk/efo/EFO_0000676, http://www.orpha.net/ORDO/Orphanet_797, http://www.ebi.ac.uk/efo/EFO_0001060, http://www.ebi.ac.uk/efo/EFO_0000729, http://www.ebi.ac.uk/efo/EFO_0000384, http://www.ebi.ac.uk/efo/EFO_0004268 GCST005563 Genome-wide genotyping array, Targeted genotyping array 143849 2017-11-06 28887542 Prins BP 2017-09-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28887542 Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. Dehydroepiandrosterone sulphate levels 5,414 European ancestry women, 4,308 European ancestry men 9,888 European ancestry individuals, 16,013 individuals Illumina [at least 23756480] (imputed) 2 dehydroepiandrosterone sulphate measurement http://www.ebi.ac.uk/efo/EFO_0007001 GCST004941 Genome-wide genotyping array 9722 2017-11-06 28887542 Prins BP 2017-09-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28887542 Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. Glycated hemoglobin levels 5,288 European ancestry women, 4,148 European ancestry men 9,888 European ancestry individuals, 16,013 individuals Illumina [at least 23756480] (imputed) 2 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST004939 Genome-wide genotyping array 9436 2017-11-06 28887542 Prins BP 2017-09-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28887542 Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. Alanine transaminase levels 5,458 European ancestry women, 4,273 European ancestry men up to 9,888 European ancestry individuals, up to 16,013 individuals Illumina [at least 23756480] (imputed) 1 serum alanine aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004735 GCST004940 Genome-wide genotyping array 9731 2017-12-19 28887542 Prins BP 2017-09-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28887542 Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. Serum albumin levels 5,501 European ancestry women, 4,323 European ancestry men 9,888 European ancestry individuals, 16,013 individuals Illumina [at least 23756480] (imputed) 0 serum albumin measurement http://www.ebi.ac.uk/efo/EFO_0004535 GCST005059 Genome-wide genotyping array 9824 2017-12-19 28887542 Prins BP 2017-09-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28887542 Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. Serum alkaline phosphatase levels 5,451 European ancestry women, 4,282 European ancestry men 9,888 European ancestry individuals, 16,013 individuals Illumina [at least 23756480] (imputed) 0 alkaline phosphatase measurement http://www.ebi.ac.uk/efo/EFO_0004533 GCST005061 Genome-wide genotyping array 9733 2017-12-19 28887542 Prins BP 2017-09-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28887542 Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. Fibrinogen levels 5,468 European ancestry women, 4,294 European ancestry men 9,888 European ancestry individuals, 16,013 individuals Illumina [at least 23756480] (imputed) 0 fibrinogen measurement http://www.ebi.ac.uk/efo/EFO_0004623 GCST005062 Genome-wide genotyping array 9762 2017-12-19 28887542 Prins BP 2017-09-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28887542 Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. Aspartate aminotransferase levels 5,321 European ancestry women, 4,142 European ancestry men 9,888 European ancestry individuals, 16,013 individuals Illumina [at least 23756480] (imputed) 0 aspartate aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004736 GCST005064 Genome-wide genotyping array 9463 2017-12-19 28887542 Prins BP 2017-09-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28887542 Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. Cholesterol, total 5,495 European ancestry women, 4,322 European ancestry men 9,888 European ancestry individuals, 16,013 individuals Illumina [at least 23756480] (imputed) 0 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST005065 Genome-wide genotyping array 9817 2017-12-19 28887542 Prins BP 2017-09-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28887542 Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. Creatinine levels 5,497 European ancestry women, 4,306 European ancestry men 9,888 European ancestry individuals, 16,013 individuals Illumina [at least 23756480] (imputed) 0 creatinine measurement http://www.ebi.ac.uk/efo/EFO_0004518 GCST005066 Genome-wide genotyping array 9803 2017-12-19 28887542 Prins BP 2017-09-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28887542 Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. Gamma glutamyl transferase levels 5,467 European ancestry women, 4,280 European ancestry men 9,888 European ancestry individuals, 16,013 individuals Illumina [at least 23756480] (imputed) 0 serum gamma-glutamyl transferase measurement http://www.ebi.ac.uk/efo/EFO_0004532 GCST005069 Genome-wide genotyping array 9747 2017-12-19 28887542 Prins BP 2017-09-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28887542 Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. HDL cholesterol 5,482 European ancestry women, 4,314 European ancestry men 9,888 European ancestry individuals, 16,013 individuals Illumina [at least 23756480] (imputed) 0 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST005058 Genome-wide genotyping array 9796 2017-12-19 28887542 Prins BP 2017-09-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28887542 Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. Hemoglobin levels 5,392 European ancestry women, 4,275 European ancestry men 9,888 European ancestry individuals, 16,013 individuals Illumina [at least 23756480] (imputed) 0 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST005060 Genome-wide genotyping array 9667 2017-12-19 28887542 Prins BP 2017-09-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28887542 Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. C-reactive protein levels 5,350 European ancestry women, 4,191 European ancestry men 9,888 European ancestry individuals, 16,013 individuals Illumina [at least 23756480] (imputed) 0 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST005067 Genome-wide genotyping array 9541 2017-12-19 28887542 Prins BP 2017-09-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28887542 Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. Insulin-like growth factor 1 levels 5,455 European ancestry women, 4,277 European ancestry men 9,888 European ancestry individuals, 16,013 individuals Illumina [at least 23756480] (imputed) 0 insulin like growth factor measurement http://www.ebi.ac.uk/efo/EFO_0004628 GCST005071 Genome-wide genotyping array 9732 2017-12-19 28887542 Prins BP 2017-09-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28887542 Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. Ferritin levels 5,499 European ancestry women, 4,319 European ancestry men 9,888 European ancestry individuals, 16,013 individuals Illumina [at least 23756480] (imputed) 0 ferritin measurement http://www.ebi.ac.uk/efo/EFO_0004459 GCST005072 Genome-wide genotyping array 9818 2017-12-19 28887542 Prins BP 2017-09-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28887542 Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. Testosterone levels 4,259 European ancestry men 9,888 European ancestry individuals, 16,013 individuals Illumina [at least 23756480] (imputed) 0 testosterone measurement http://www.ebi.ac.uk/efo/EFO_0004908 GCST005074 Genome-wide genotyping array 4259 2017-12-19 28887542 Prins BP 2017-09-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28887542 Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. Triglyceride levels 5,482 European ancestry women, 4,263 European ancestry men 9,888 European ancestry individuals, 16,013 individuals Illumina [at least 23756480] (imputed) 0 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST005073 Genome-wide genotyping array 9745 2017-12-19 28887542 Prins BP 2017-09-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28887542 Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. Urea levels 5,498 European ancestry women, 4,320 European ancestry men 9,888 European ancestry individuals, 16,013 individuals Illumina [at least 23756480] (imputed) 0 blood urea nitrogen measurement http://www.ebi.ac.uk/efo/EFO_0004741 GCST005070 Genome-wide genotyping array 9818 2017-12-19 28887542 Prins BP 2017-09-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28887542 Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. LDL cholesterol up to 5,574 European ancestry women, up to 4,387 European ancestry men 9,888 European ancestry individuals, 16,013 individuals Illumina [at least 23756480] (imputed) 0 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST005068 Genome-wide genotyping array 9961 2017-12-19 28887542 Prins BP 2017-09-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28887542 Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations. Glomerular filtration rate up to 5,574 European ancestry women, up to 4,387 European ancestry men 9,888 European ancestry individuals, 16,013 individuals Illumina [at least 23756480] (imputed) 0 glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0005208 GCST005063 Genome-wide genotyping array 9961 2018-04-25 23143594 Tsoi LC 2012-12-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23143594 Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Psoriasis 10,588 European ancestry cases, 22,806 European ancestry controls NA Illumina [111236] (imputed) 41 psoriasis http://www.ebi.ac.uk/efo/EFO_0000676 GCST005527 Targeted genotyping array [ImmunoChip] 33394 2017-02-08 27577874 Evans DS 2016-08-29 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/27577874 Fine-mapping, novel loci identification, and SNP association transferability in a genome-wide association study of QRS duration in African Americans. QRS duration up to 13,031 African American individuals, 40,407 European ancestry individuals NA Affymetrix, Illumina [2955816] (imputed) 54 QRS duration http://www.ebi.ac.uk/efo/EFO_0005055 GCST003598 Genome-wide genotyping array 53438 2017-02-19 26138065 Schneider BP 2015-07-02 Clin Cancer Res www.ncbi.nlm.nih.gov/pubmed/26138065 Genome-Wide Association Studies for Taxane-Induced Peripheral Neuropathy in ECOG-5103 and ECOG-1199. Neuropathy in taxane-treated breast cancer 151 African American cases, 576 European ancestry cases, 62 African American controls, 781 European ancestry controls 52 African American cases, 437 European ancestry cases, 38 African American controls, 352 European ancestry controls Illumina [at least 810891] (imputed) 0 peripheral neuropathy, response to docetaxel, response to paclitaxel http://www.ebi.ac.uk/efo/EFO_0003100, http://purl.obolibrary.org/obo/GO_1902519, http://purl.obolibrary.org/obo/GO_1901555 GCST003627 Genome-wide genotyping array 1570 2017-09-10 28525603 Ortega-Alonso A 2017-05-19 Schizophr Bull www.ncbi.nlm.nih.gov/pubmed/28525603 Genome-Wide Association Study of Psychosis Proneness in the Finnish Population. Psychosis proneness (hypomanic personality scale) 3,967 Finnish ancestry individuals NA Illumina [~ 9600000] (imputed) 6 psychosis predisposition measurement http://www.ebi.ac.uk/efo/EFO_0008337 GCST004678 Genome-wide genotyping array 3967 2017-09-10 28525603 Ortega-Alonso A 2017-05-19 Schizophr Bull www.ncbi.nlm.nih.gov/pubmed/28525603 Genome-Wide Association Study of Psychosis Proneness in the Finnish Population. Psychosis proneness (perceptual aberration scale) 4,057 Finnish ancestry individuals NA Illumina [~ 9600000] (imputed) 3 psychosis predisposition measurement http://www.ebi.ac.uk/efo/EFO_0008337 GCST004685 Genome-wide genotyping array 4057 2017-09-10 28525603 Ortega-Alonso A 2017-05-19 Schizophr Bull www.ncbi.nlm.nih.gov/pubmed/28525603 Genome-Wide Association Study of Psychosis Proneness in the Finnish Population. Psychosis proneness (revised physical anhedonia scale) 3,988 Finnish ancestry individuals NA Illumina [~ 9600000] (imputed) 1 psychosis predisposition measurement http://www.ebi.ac.uk/efo/EFO_0008337 GCST004680 Genome-wide genotyping array 3988 2017-09-10 28525603 Ortega-Alonso A 2017-05-19 Schizophr Bull www.ncbi.nlm.nih.gov/pubmed/28525603 Genome-Wide Association Study of Psychosis Proneness in the Finnish Population. Psychosis proneness (revised social anhedonia scale) 4,025 Finnish ancestry individuals NA Illumina [~ 9600000] (imputed) 2 psychosis predisposition measurement http://www.ebi.ac.uk/efo/EFO_0008337 GCST004686 Genome-wide genotyping array 4025 2017-09-10 28525603 Ortega-Alonso A 2017-05-19 Schizophr Bull www.ncbi.nlm.nih.gov/pubmed/28525603 Genome-Wide Association Study of Psychosis Proneness in the Finnish Population. Psychosis proneness (hypomanic personality scale and perceptual aberration scale) 3,824 Finnish ancestry individuals NA Illumina [~ 9600000] (imputed) 4 psychosis predisposition measurement http://www.ebi.ac.uk/efo/EFO_0008337 GCST004679 Genome-wide genotyping array 3824 2017-09-10 28525603 Ortega-Alonso A 2017-05-19 Schizophr Bull www.ncbi.nlm.nih.gov/pubmed/28525603 Genome-Wide Association Study of Psychosis Proneness in the Finnish Population. Psychosis proneness (schizoidia scale) 4,191 Finnish ancestry individuals NA Illumina [~ 9600000] (imputed) 0 psychosis predisposition measurement http://www.ebi.ac.uk/efo/EFO_0008337 GCST004687 Genome-wide genotyping array 4191 2017-09-10 28525603 Ortega-Alonso A 2017-05-19 Schizophr Bull www.ncbi.nlm.nih.gov/pubmed/28525603 Genome-Wide Association Study of Psychosis Proneness in the Finnish Population. Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale) 3,787 Finnish ancestry individuals NA Illumina [~ 9600000] (imputed) 6 psychosis predisposition measurement http://www.ebi.ac.uk/efo/EFO_0008337 GCST004681 Genome-wide genotyping array 3787 2017-09-10 28525603 Ortega-Alonso A 2017-05-19 Schizophr Bull www.ncbi.nlm.nih.gov/pubmed/28525603 Genome-Wide Association Study of Psychosis Proneness in the Finnish Population. Psychosis proneness (hypomanic personality scale and revised social anhedonia scale) 3,837 Finnish ancestry individuals NA Illumina [~ 9600000] (imputed) 5 psychosis predisposition measurement http://www.ebi.ac.uk/efo/EFO_0008337 GCST004682 Genome-wide genotyping array 3837 2017-09-10 28525603 Ortega-Alonso A 2017-05-19 Schizophr Bull www.ncbi.nlm.nih.gov/pubmed/28525603 Genome-Wide Association Study of Psychosis Proneness in the Finnish Population. Psychosis proneness (perceptual aberration scale and revised physical anhedonia scale) 3,812 Finnish ancestry individuals NA Illumina [~ 9600000] (imputed) 1 psychosis predisposition measurement http://www.ebi.ac.uk/efo/EFO_0008337 GCST004688 Genome-wide genotyping array 3812 2017-09-10 28525603 Ortega-Alonso A 2017-05-19 Schizophr Bull www.ncbi.nlm.nih.gov/pubmed/28525603 Genome-Wide Association Study of Psychosis Proneness in the Finnish Population. Psychosis proneness (perceptual aberration scale and revised social anhedonia scale) 3,868 Finnish ancestry individuals NA Illumina [~ 9600000] (imputed) 2 psychosis predisposition measurement http://www.ebi.ac.uk/efo/EFO_0008337 GCST004683 Genome-wide genotyping array 3868 2017-09-10 28525603 Ortega-Alonso A 2017-05-19 Schizophr Bull www.ncbi.nlm.nih.gov/pubmed/28525603 Genome-Wide Association Study of Psychosis Proneness in the Finnish Population. Psychosis proneness (revised physical anhedonia scale and revised social anhedonia scale) 3,820 Finnish ancestry individuals NA Illumina [~ 9600000] (imputed) 2 psychosis predisposition measurement http://www.ebi.ac.uk/efo/EFO_0008337 GCST004684 Genome-wide genotyping array 3820 2017-08-02 28512992 Joo YB 2017-05-16 Int J Rheum Dis www.ncbi.nlm.nih.gov/pubmed/28512992 Association of CD8+ T-cells with bone erosion in patients with rheumatoid arthritis. Bone erosion in rheumatoid arthritis 385 Korean ancestry cases, 326 Korean ancestry controls NA Illumina [439289] 2 joint damage measurement http://www.ebi.ac.uk/efo/EFO_0005413 GCST004400 Genome-wide genotyping array 711 2017-09-18 28604730 McKay JD 2017-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28604730 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. Lung cancer 29,266 European ancestry cases, 56,450 European ancestry controls NA Illumina [10439017] (imputed) 135 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST004748 Genome-wide genotyping array 85716 2017-09-18 28604730 McKay JD 2017-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28604730 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. Lung adenocarcinoma 11,273 European ancestry cases, 55,483 European ancestry controls NA Illumina [10439017] (imputed) 79 lung adenocarcinoma http://www.ebi.ac.uk/efo/EFO_0000571 GCST004744 Genome-wide genotyping array 66756 2017-09-18 28604730 McKay JD 2017-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28604730 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. Squamous cell lung carcinoma 7,426 European ancestry cases, 55,627 European ancestry controls NA Illumina [10439017] (imputed) 101 squamous cell lung carcinoma http://www.ebi.ac.uk/efo/EFO_0000708 GCST004750 Genome-wide genotyping array 63053 2017-09-18 28604730 McKay JD 2017-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28604730 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. Small cell lung carcinoma 2,664 European ancestry cases, 21,444 European ancestry controls NA Illumina [10439017] (imputed) 50 small cell lung carcinoma http://www.ebi.ac.uk/efo/EFO_0000702 GCST004746 Genome-wide genotyping array 24108 2017-09-18 28604730 McKay JD 2017-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28604730 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. Lung cancer in ever smokers 23,223 European ancestry cases, 16,964 European ancestry controls NA Illumina [10439017] (imputed) 111 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST004749 Genome-wide genotyping array 40187 2017-09-18 28604730 McKay JD 2017-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28604730 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. Lung cancer in never smokers 2,355 European ancestry cases, 7,504 European ancestry controls NA Illumina [10439017] (imputed) 23 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST004747 Genome-wide genotyping array 9859 2017-10-23 28877031 Zhang G 2017-09-07 N Engl J Med www.ncbi.nlm.nih.gov/pubmed/28877031 Genetic Associations with Gestational Duration and Spontaneous Preterm Birth. Preterm birth (maternal effect) 3,331 European ancestry preterm birth mothers, 40,236 European ancestry term birth mothers 2,565 European ancestry preterm birth mothers, 6,034 European ancestry term birth mothers Illumina [15635593] (imputed) 5 premature birth, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0003917, http://www.ebi.ac.uk/efo/EFO_0005939 GCST004898 Genome-wide genotyping array 43567 2017-10-23 28877031 Zhang G 2017-09-07 N Engl J Med www.ncbi.nlm.nih.gov/pubmed/28877031 Genetic Associations with Gestational Duration and Spontaneous Preterm Birth. Gestational age at birth (maternal effect) 43,568 European ancestry mothers 8,643 European ancestry mothers Illumina [15635593] (imputed) 11 gestational age, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0005112, http://www.ebi.ac.uk/efo/EFO_0005939 GCST004899 Genome-wide genotyping array 43568 2018-04-25 23749187 Cortes A 2013-07-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23749187 Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci. Ankylosing spondylitis 9,069 European ancestry cases, 1,550 East Asian ancestry cases, 13,578 European ancestry controls, 1,567 East Asian ancestry controls NA Illumina [128935] 70 ankylosing spondylitis http://www.ebi.ac.uk/efo/EFO_0003898 GCST005529 Targeted genotyping array [ImmunoChip] 25764 2018-04-25 23749187 Cortes A 2013-07-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23749187 Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci. Ankylosing spondylitis (SNP x SNP interaction) 9,069 European ancestry cases, 13,578 European ancestry controls NA Illumina [128935] 2 ankylosing spondylitis http://www.ebi.ac.uk/efo/EFO_0003898 GCST005530 Targeted genotyping array [ImmunoChip] 22647 2017-03-20 28171663 Huo D 2016-09-04 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28171663 Genome-wide association studies in women of African ancestry identified 3q26.21 as a novel susceptibility locus for oestrogen receptor negative breast cancer. Breast cancer 3962 African American cases, 711 African ancestry cases, 4,150 African ancestry controls, 624 African ancestry controls 1,984 African American cases, 2,939 African American controls Illumina [16147413] (imputed) 2 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST003782 Genome-wide genotyping array 9447 2017-03-20 28171663 Huo D 2016-09-04 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28171663 Genome-wide association studies in women of African ancestry identified 3q26.21 as a novel susceptibility locus for oestrogen receptor negative breast cancer. Breast cancer (estrogen-receptor positive) 1795 African American cases, 99 African ancestry cases, 4,150 African American controls, 624 African ancestry controls 1093 African American cases, 2939 African American controls Illumina [16147413] (imputed) 1 estrogen-receptor positive breast cancer http://www.ebi.ac.uk/efo/EFO_1000649 GCST003781 Genome-wide genotyping array 6668 2017-03-20 28171663 Huo D 2016-09-04 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28171663 Genome-wide association studies in women of African ancestry identified 3q26.21 as a novel susceptibility locus for oestrogen receptor negative breast cancer. Breast cancer (estrogen-receptor negative) 1349 African American cases, 42 African ancestry cases, 4,150 African American controls, 624 African ancestry controls 573 African American cases, 2,939 African American controls Illumina [16147413] (imputed) 2 estrogen-receptor negative breast cancer http://www.ebi.ac.uk/efo/EFO_1000650 GCST003780 Genome-wide genotyping array 6165 2017-04-23 27595289 Goyal RK 2016-09-05 Bone Marrow Transplant www.ncbi.nlm.nih.gov/pubmed/27595289 Novel HLA-DP region susceptibility loci associated with severe acute GvHD. Acute graft versus host disease in bone marrow transplantation (recipient effect) 291 European ancestry recipients with acute graft versus host disease, 288 European ancestry recipients without acute graft versus host disease NA Affymetrix [905761] 19 acute graft vs. host disease http://www.ebi.ac.uk/efo/EFO_0004599 GCST003941 Genome-wide genotyping array 579 2017-04-23 27595289 Goyal RK 2016-09-05 Bone Marrow Transplant www.ncbi.nlm.nih.gov/pubmed/27595289 Novel HLA-DP region susceptibility loci associated with severe acute GvHD. Acute graft versus host disease in bone marrow transplantation (donor effect) 315 European ancestry donors (recipients with acute graft versus host disease), 341 European ancestry donors (recipients without graft versus host disease) NA Affymetrix [905761] 3 acute graft vs. host disease, donor genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0004599, http://www.ebi.ac.uk/efo/EFO_0007892 GCST003942 Genome-wide genotyping array 656 2017-03-13 27527254 Gharahkhani P 2016-08-12 Lancet Oncol www.ncbi.nlm.nih.gov/pubmed/27527254 Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis. Barrett's esophagus 6,167 European ancestry cases, 17,159 European ancestry controls NA Illumina [11942825] (imputed) 5 Barrett's esophagus http://www.ebi.ac.uk/efo/EFO_0000280 GCST003738 Genome-wide genotyping array 23326 2017-03-13 27527254 Gharahkhani P 2016-08-12 Lancet Oncol www.ncbi.nlm.nih.gov/pubmed/27527254 Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis. Esophageal adenocarcinoma 4,112 European ancestry cases, 17,159 European ancestry controls NA Illumina [13074274] (imputed) 5 esophageal adenocarcinoma http://www.ebi.ac.uk/efo/EFO_0000478 GCST003739 Genome-wide genotyping array 21271 2017-03-13 27527254 Gharahkhani P 2016-08-12 Lancet Oncol www.ncbi.nlm.nih.gov/pubmed/27527254 Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis. Barrett's esophagus or Esophageal adenocarcinoma 6,167 European ancestry Barrett's oesophagus cases, 4,112 European ancestry esophageal adenocarcinoma cases, 17,159 European ancestry controls NA Illumina [11951684] (imputed) 14 esophageal adenocarcinoma, Barrett's esophagus http://www.ebi.ac.uk/efo/EFO_0000478, http://www.ebi.ac.uk/efo/EFO_0000280 GCST003740 Genome-wide genotyping array 27438 2017-03-20 27588450 Mahajan A 2016-09-01 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27588450 Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity. Glomerular filtration rate 23,553 European ancestry individuals, 23,536 Japanese individuals, 16,325 Hispanic individuals, 8,224 African American individuals NA Affymetrix, Illumina [at least 6581000] (imputed) 42 glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0005208 GCST003790 Genome-wide genotyping array 71638 2017-08-18 28448500 Graff M 2017-04-27 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28448500 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) 2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals 6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 141 BMI-adjusted waist-hip ratio, physical activity measurement http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002 GCST004567 Genome-wide genotyping array 156653 2017-08-18 28448500 Graff M 2017-04-27 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28448500 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Body mass index 2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals 6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 266 physical activity measurement, body mass index http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340 GCST004557 Genome-wide genotyping array 161368 2017-08-18 28448500 Graff M 2017-04-27 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28448500 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Waist circumference adjusted for body mass index 2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals 6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 260 BMI-adjusted waist circumference http://www.ebi.ac.uk/efo/EFO_0007789 GCST004562 Genome-wide genotyping array 160475 2017-08-22 28448500 Graff M 2017-04-27 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28448500 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Waist-to-hip ratio adjusted for body mass index 2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals 6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 145 BMI-adjusted waist-hip ratio, physical activity measurement http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002 GCST004576 Genome-wide genotyping array 156653 2017-08-18 28448500 Graff M 2017-04-27 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28448500 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Body mass index (physical activity interaction) 2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals 6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 2 physical activity measurement, body mass index http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340 GCST004568 Genome-wide genotyping array 161368 2017-08-18 28448500 Graff M 2017-04-27 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28448500 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Waist circumference adjusted for BMI (physical activity interaction) 2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals 6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 0 BMI-adjusted waist circumference, physical activity measurement http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002 GCST004561 Genome-wide genotyping array 160475 2017-08-18 28448500 Graff M 2017-04-27 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28448500 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Waist-to-hip ratio adjusted for BMI (physical activity interaction) 2,518 African American women, 83,707 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 52,993 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals 6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 0 BMI-adjusted waist-hip ratio, physical activity measurement http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0008002 GCST004566 Genome-wide genotyping array 156653 2017-08-18 28448500 Graff M 2017-04-27 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28448500 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Body mass index (joint analysis main effects and physical activity interaction) 2,518 African American women, 86,278 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 55,137 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals 6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 242 physical activity measurement, body mass index http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340 GCST004558 Genome-wide genotyping array 161368 2017-08-18 28448500 Graff M 2017-04-27 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28448500 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) 2,518 African American women, 85,730 European ancestry women, 1,773 Filipino ancestry women, 1,030 Indian ancestry women, 1,457 African American men, 54,792 European ancestry men, 7,648 Indian ancestry men, 5,527 European ancestry individuals 6,244 African American women, 17,531 European ancestry women, 329 African American men, 19,956 European ancestry men Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 253 BMI-adjusted waist circumference, physical activity measurement http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0008002 GCST004563 Genome-wide genotyping array 160475 2017-08-18 28448500 Graff M 2017-04-27 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28448500 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Body mass index in physically active individuals 1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,609 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,399 European ancestry men, at least 4,819 European ancestry individuals 4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 195 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST004559 Genome-wide genotyping array 123097 2017-08-18 28448500 Graff M 2017-04-27 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28448500 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Body mass index in physically inactive individuals 561 African American women, 352 Filipino ancestry women, 725 Indian ancestry women, 19,366 European ancestry women, 251 African American men, 4,654 Indian ancestry men, 11,727 European ancestry men, 959 European ancestry individuals 1,437 African American women, 5,184 European ancestry women, 64 African American men, 5,416 European ancestry men Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 45 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST004560 Genome-wide genotyping array 38595 2017-08-18 28448500 Graff M 2017-04-27 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28448500 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Waist circumference adjusted for BMI in active individuals 1,957 African American women, 1,773 Filipino ancestry women, 305 Indian ancestry women, 67,139 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 43,100 European ancestry men, at least 4,819 European ancestry individuals 4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 235 BMI-adjusted waist circumference http://www.ebi.ac.uk/efo/EFO_0007789 GCST004564 Genome-wide genotyping array 122328 2017-08-18 28448500 Graff M 2017-04-27 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28448500 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Waist circumference adjusted for BMI in inactive individuals 561 African American women, 352 Filipino ancestry women, 725 Indian ancestry women, 19,288 European ancestry women, 251 African American men, 4,654 Indian ancestry men, 11,681 European ancestry men, 959 European ancestry individuals 1,437 African American women, 5,184 European ancestry women, 64 African American men, 5,416 European ancestry men Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 14 BMI-adjusted waist circumference http://www.ebi.ac.uk/efo/EFO_0007789 GCST004565 Genome-wide genotyping array 38471 2017-08-22 28448500 Graff M 2017-04-27 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28448500 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Waist-to-hip ratio adjusted for BMI in active individuals 1,957 African American women, 1,421 Filipino ancestry women, 305 Indian ancestry women, 65,539 European ancestry women, 1,206 African American men, 2,029 Indian ancestry men, 41,673 European ancestry men, 4,819 European ancestry individuals 4,807 African American women, 12,347 European ancestry women, 265 African American men, 14,540 European ancestry men Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 143 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST004578 Genome-wide genotyping array 118949 2017-08-22 28448500 Graff M 2017-04-27 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28448500 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Waist-to-hip ratio adjusted for BMI in inactive individuals 561 African American women, 352 Filipino ancestry women, 725 Indian ancestry women, 18,865 European ancestry women, 251 African American men, 4,654 Indian ancestry men, 11,309 European ancestry men, 959 European ancestry individuals 1,437 African American women, 5,184 European ancestry women, 64 African American men, 5,416 European ancestry men Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 8 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST004577 Genome-wide genotyping array 37676 2017-06-12 28163062 Matsuura K 2017-02-02 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/28163062 Genome-Wide Association Study Identifies TLL1 Variant Associated With Development of Hepatocellular Carcinoma After Eradication of Hepatitis C Virus Infection. Hepatocellular carcinoma in post hepatitis C eradication by interferon therapy 123 Japanese ancestry hepatocellular carcinoma cases, 333 Japanese ancestry 5-yr hepatocellular carcinoma-free controls 130 Japanese ancestry hepatocellular carcinoma cases, 210 Japanese ancestry 5-yr hepatocellular carcinoma-free controls Affymetrix [443299] 1 response to interferon, hepatocellular carcinoma http://www.ebi.ac.uk/efo/EFO_0007859, http://www.ebi.ac.uk/efo/EFO_0000182 GCST004160 Genome-wide genotyping array 461 2018-03-23 29364747 Jonsson L 2018-01-01 J Dent Res www.ncbi.nlm.nih.gov/pubmed/29364747 Rare and Common Variants Conferring Risk of Tooth Agenesis. Tooth agenesis 1,944 Icelandic ancestry cases, 338,554 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals) 151 European ancestry cases, 6,019 European ancestry controls, 150 European and other ancestry cases, 2,696 European and other ancestry controls Illumina [NR] (imputed) 4 tooth agenesis http://www.ebi.ac.uk/efo/EFO_0005410 GCST005389 Genome-wide genotyping array 340498 2018-03-23 29364747 Jonsson L 2018-01-01 J Dent Res www.ncbi.nlm.nih.gov/pubmed/29364747 Rare and Common Variants Conferring Risk of Tooth Agenesis. Tooth agenesis (mandibular second premolars) 1,196 Icelandic ancestry cases, 338,554 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals) 66 European ancestry cases, 4,667 European ancestry controls, 82 European and other ancestry cases, 2,696 European and other ancestry controls Illumina [NR] (imputed) 1 tooth agenesis http://www.ebi.ac.uk/efo/EFO_0005410 GCST005390 Genome-wide genotyping array 339750 2018-03-23 29364747 Jonsson L 2018-01-01 J Dent Res www.ncbi.nlm.nih.gov/pubmed/29364747 Rare and Common Variants Conferring Risk of Tooth Agenesis. Tooth agenesis (maxillary lateral incisors) 600 Icelandic ancestry cases, 338,554 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals) 102 European ancestry cases, 204 European ancestry controls, 32 European and other ancestry cases, 2,696 European and other ancestry controls Illumina [NR] (imputed) 2 tooth agenesis http://www.ebi.ac.uk/efo/EFO_0005410 GCST005391 Genome-wide genotyping array 339154 2018-03-23 29364747 Jonsson L 2018-01-01 J Dent Res www.ncbi.nlm.nih.gov/pubmed/29364747 Rare and Common Variants Conferring Risk of Tooth Agenesis. Tooth agenesis (maxillary second premolars) 600 Icelandic ancestry cases, 338,554 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals) NA Illumina [NR] (imputed) 1 tooth agenesis http://www.ebi.ac.uk/efo/EFO_0005410 GCST005392 Genome-wide genotyping array 339154 2017-08-11 28520984 Saccone NL 2017-05-17 Nicotine Tob Res www.ncbi.nlm.nih.gov/pubmed/28520984 Genome-wide association study of heavy smoking and daily/nondaily smoking in the Hispanic Community Health Study / Study of Latinos (HCHS/SOL). Smoking status (daily vs non-daily) 778 Hispanic non-daily smoker cases, 1,786 Hispanic daily smoker controls 85 Hispanic non-daily smokers, 343 Hispanic daily smokers, 158 African American non-daily smokers, 1,106 African American daily smokers, 232 European ancestry non-daily smokers, 1,316 European ancestry daily smokers Illumina [at least 2400000] (imputed) 0 smoking behaviour measurement http://www.ebi.ac.uk/efo/EFO_0005671 GCST004511 Genome-wide genotyping array 2564 2017-08-11 28520984 Saccone NL 2017-05-17 Nicotine Tob Res www.ncbi.nlm.nih.gov/pubmed/28520984 Genome-wide association study of heavy smoking and daily/nondaily smoking in the Hispanic Community Health Study / Study of Latinos (HCHS/SOL). Smoking status (heavy vs light) 1,929 Hispanic heavy smoker cases, 3,156 Hispanic light smoker controls NA Illumina [~ 11400000] (imputed) 2 smoking behaviour measurement http://www.ebi.ac.uk/efo/EFO_0005671 GCST004512 Genome-wide genotyping array 5085 2017-08-11 28520984 Saccone NL 2017-05-17 Nicotine Tob Res www.ncbi.nlm.nih.gov/pubmed/28520984 Genome-wide association study of heavy smoking and daily/nondaily smoking in the Hispanic Community Health Study / Study of Latinos (HCHS/SOL). Smoking status (current vs former) 2,564 Hispanic current smoker cases, 2,555 Hispanic former smoker controls NA Illumina [at least 2400000] (imputed) 0 smoking status measurement http://www.ebi.ac.uk/efo/EFO_0006527 GCST004513 Genome-wide genotyping array 5119 2017-08-11 28520984 Saccone NL 2017-05-17 Nicotine Tob Res www.ncbi.nlm.nih.gov/pubmed/28520984 Genome-wide association study of heavy smoking and daily/nondaily smoking in the Hispanic Community Health Study / Study of Latinos (HCHS/SOL). Smoking status (ever vs never smokers) 5,119 Hispanic ever smoker cases, 7,616 Hispanic never smoker controls NA Illumina [at least 2400000] (imputed) 0 smoking status measurement http://www.ebi.ac.uk/efo/EFO_0006527 GCST004514 Genome-wide genotyping array 12735 2017-07-10 28416818 Christophersen IE 2017-04-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28416818 Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Atrial fibrillation 15,979 European ancestry cases, 102,776 European ancestry controls, 641 African American cases, 5,234 African American controls, 837 Japanese ancestry cases, 3,293 Japanese controls, 277 Hispanic cases, 3,081 Hispanic controls,197 Brazilian ancestry cases, 758 Brazilian ancestry controls. 8,180 Japanese ancestry cases, 28,612 Japanese ancestry controls. Affymetrix, Illumina [11795432] (imputed) 10 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST004295 Genome-wide genotyping array 133073 2017-07-10 28416818 Christophersen IE 2017-04-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28416818 Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Atrial fibrillation 15,979 European ancestry cases, 102,776 European ancestry controls, 641 African American cases, 5,234 African American controls, 837 Japanese ancestry cases, 3,293 Japanese controls, 277 Hispanic cases, 3,081 Hispanic controls,197 Brazilian ancestry cases, 758 Brazilian ancestry controls. 3,666 cases, 139,852 controls Affymetrix, Illumina [11795432] (imputed) 8 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST004296 Genome-wide genotyping array 133073 2017-07-10 28416818 Christophersen IE 2017-04-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28416818 Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Atrial fibrillation 15,979 European ancestry cases, 102,776 European ancestry controls. NA Affymetrix, Illumina [11795432] (imputed) 20 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST004297 Genome-wide genotyping array 118755 2017-07-10 28416818 Christophersen IE 2017-04-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28416818 Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Atrial fibrillation 837 Japanese ancestry cases, 3,293 Japanese controls 8,180 Japanese ancestry cases, 28,612 Japanese ancestry controls. Affymetrix, Illumina [11795432] (imputed) 1 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST004298 Genome-wide genotyping array 4130 2017-07-10 28416818 Christophersen IE 2017-04-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28416818 Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Atrial fibrillation 641 African American cases, 5,234 African American controls 447 African American cases, 442 African American controls Affymetrix, Illumina [11795432] (imputed) 1 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST004299 Genome-wide genotyping array 5875 2017-07-10 28416818 Christophersen IE 2017-04-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28416818 Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Incident atrial fibrillation 7,323 European ancestry cases, 102,776 European ancestry controls. NA Affymetrix, Illumina [at least 3187278] (imputed) 5 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST004300 Genome-wide genotyping array 110099 2017-07-10 28416818 Christophersen IE 2017-04-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28416818 Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Prevalent atrial fibrillation 8,656 European ancestry cases, 102,776 European ancestry controls. NA Affymetrix, Illumina [at least 3187278] (imputed) 9 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST004301 Genome-wide genotyping array 111432 2017-07-27 28461288 Yan Q 2017-05-01 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/28461288 A meta-analysis of genome-wide association studies of asthma in Puerto Ricans. Asthma 1,666 Puerto Rican child cases, 478 Puerto Rican adult cases, 1,505 Puerto Rican child controls, 1,388 Puerto Rican adult controls NA Affymetrix, Illumina [7485508] (imputed) 3 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST004390 Genome-wide genotyping array 5037 2017-06-19 28459102 Zhang S 2016-04-20 JDR Clin Trans Res www.ncbi.nlm.nih.gov/pubmed/28459102 The Novel ASIC2 Locus is Associated with Severe Gingival Inflammation. Severe gingival inflammation 4,077 European American individuals NA Affymetrix [2500000] (imputed) 5 Gingival bleeding http://purl.obolibrary.org/obo/HP_0000225 GCST004198 Genome-wide genotyping array 4077 2017-09-14 28468790 Agopian AJ 2017-06-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/28468790 Genome-Wide Association Studies and Meta-Analyses for Congenital Heart Defects. Left ventricular obstructive tract defect (inherited effect) 247 European ancestry trios, 70 non-European ancestry trios, 192 European and other ancestry trios NA Illumina [at least 4483243] (imputed) 15 congenital left-sided heart lesions http://www.ebi.ac.uk/efo/EFO_0005938 GCST004719 Genome-wide genotyping array 509 2017-09-14 28468790 Agopian AJ 2017-06-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/28468790 Genome-Wide Association Studies and Meta-Analyses for Congenital Heart Defects. Conotruncal heart defects (maternal effects) up to 838 European ancestry trios NA Illumina [at least 4756722] (imputed) 22 Conotruncal heart malformations http://www.orpha.net/ORDO/Orphanet_2445 GCST004723 Genome-wide genotyping array 838 2017-09-14 28468790 Agopian AJ 2017-06-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/28468790 Genome-Wide Association Studies and Meta-Analyses for Congenital Heart Defects. Left ventricular obstructive tract defect (maternal effect) up to 439 European ancestry trios NA Illumina [at least 4756722] (imputed) 9 congenital left-sided heart lesions http://www.ebi.ac.uk/efo/EFO_0005938 GCST004722 Genome-wide genotyping array 439 2017-09-14 28468790 Agopian AJ 2017-06-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/28468790 Genome-Wide Association Studies and Meta-Analyses for Congenital Heart Defects. Congenital heart disease (inherited effect) 1,119 European ancestry trios, 406 European ancestry cases, 2,976 European ancestry controls, 415 non-European ancestry trios NA Illumina [at least 4756772] (imputed) 10 congenital heart disease http://www.ebi.ac.uk/efo/EFO_0005207 GCST004718 Genome-wide genotyping array 4916 2017-09-14 28468790 Agopian AJ 2017-06-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/28468790 Genome-Wide Association Studies and Meta-Analyses for Congenital Heart Defects. Congenital heart disease (maternal effect) 1,119 European ancestry trios NA Illumina [at least 4756722] (imputed) 20 congenital heart disease http://www.ebi.ac.uk/efo/EFO_0005207 GCST004721 Genome-wide genotyping array 1119 2017-09-14 28468790 Agopian AJ 2017-06-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/28468790 Genome-Wide Association Studies and Meta-Analyses for Congenital Heart Defects. Conotruncal heart defects (inherited effects) 483 European ancestry trios, 406 European ancestry cases, 2,976 European ancestry controls, 355 European and other ancestry trios, 187 non-European ancestry trios. NA Illumina [at least 4756722] (imputed) 10 Conotruncal heart malformations http://www.orpha.net/ORDO/Orphanet_2445 GCST004720 Genome-wide genotyping array 4407 2017-07-14 28460022 Lee JY 2017-04-27 Eur Heart J www.ncbi.nlm.nih.gov/pubmed/28460022 Korean atrial fibrillation network genome-wide association study for early-onset atrial fibrillation identifies novel susceptibility loci. Early onset atrial fibrillation 672 Korean ancestry cases, 3,700 Korean ancestry controls 200 Korean ancestry cases, 1,812 Korean ancestry controls Affymetrix [642422] 6 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST004352 Genome-wide genotyping array 4372 2017-10-09 28199695 Jones AV 2017-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28199695 GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci. Itch intensity from mosquito bite 84,724 European ancestry individuals NA Illumina [13520550] (imputed) 98 mosquito bite reaction itch intensity measurement http://www.ebi.ac.uk/efo/EFO_0008377 GCST004861 Genome-wide genotyping array 84724 2017-10-09 28199695 Jones AV 2017-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28199695 GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci. Itch intensity from mosquito bite adjusted by bite size 41,355 European ancestry men and 43,369 European ancestry women NA Illumina [13520550] (imputed) 240 mosquito bite reaction itch intensity measurement, mosquito bite reaction size measurement http://www.ebi.ac.uk/efo/EFO_0008377, http://www.ebi.ac.uk/efo/EFO_0008378 GCST004862 Genome-wide genotyping array 84724 2017-10-09 28199695 Jones AV 2017-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28199695 GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci. Mosquito bite size 84,724 European ancestry individuals NA Illumina [13520550] (imputed) 147 mosquito bite reaction size measurement http://www.ebi.ac.uk/efo/EFO_0008378 GCST004863 Genome-wide genotyping array 84724 2017-10-09 28199695 Jones AV 2017-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28199695 GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci. Perceived unattractiveness to mosquitoes 16,576 European ancestry individuals NA Illumina [7433384] (imputed) 45 perceived unattractiveness to mosquitos measurement http://www.ebi.ac.uk/efo/EFO_0008380 GCST004864 Genome-wide genotyping array 16576 2017-10-09 28199695 Jones AV 2017-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28199695 GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci. Itch intensity from mosquito bite adjusted by bite size 69,057 European ancestry individuals without immune related conditions NA Illumina [13519193] (imputed) 96 mosquito bite reaction itch intensity measurement, mosquito bite reaction size measurement http://www.ebi.ac.uk/efo/EFO_0008377, http://www.ebi.ac.uk/efo/EFO_0008378 GCST004865 Genome-wide genotyping array 69057 2017-08-08 28439531 Aslibekyan S 2017-03-08 J Nutr Intermed Metab www.ncbi.nlm.nih.gov/pubmed/28439531 Genome- and CD4+ T-cell methylome-wide association study of circulating trimethylamine-N-oxide in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN). Plasma trimethylamine N-oxide levels 626 European ancestry individuals NA Affymetrix [9432837] (imputed) 12 plasma trimethylamine N-oxide measurement http://www.ebi.ac.uk/efo/EFO_0005691 GCST004484 Genome-wide genotyping array 626 2017-08-30 27863252 Astle WJ 2016-11-17 Cell www.ncbi.nlm.nih.gov/pubmed/27863252 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. Myeloid white cell count 169,219 European ancestry individuals NA Affymetrix [~ 2500000] (imputed) 164 myeloid white cell count http://www.ebi.ac.uk/efo/EFO_0007988 GCST004626 Genome-wide genotyping array 169219 2017-08-30 27863252 Astle WJ 2016-11-17 Cell www.ncbi.nlm.nih.gov/pubmed/27863252 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. Lymphocyte counts 171,643 European ancestry individuals NA Affymetrix [~ 2500000] (imputed) 188 lymphocyte count http://www.ebi.ac.uk/efo/EFO_0004587 GCST004627 Genome-wide genotyping array 171643 2017-08-30 27863252 Astle WJ 2016-11-17 Cell www.ncbi.nlm.nih.gov/pubmed/27863252 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. Immature fraction of reticulocytes 170,548 European ancestry individuals NA Affymetrix [~ 2500000] (imputed) 152 reticulocyte count http://www.ebi.ac.uk/efo/EFO_0007986 GCST004628 Genome-wide genotyping array 170548 2017-08-30 27863252 Astle WJ 2016-11-17 Cell www.ncbi.nlm.nih.gov/pubmed/27863252 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. Neutrophil count 170,702 European ancestry individuals NA Affymetrix [~ 2500000] (imputed) 152 neutrophil count http://www.ebi.ac.uk/efo/EFO_0004833 GCST004629 Genome-wide genotyping array 170702 2017-08-30 27863252 Astle WJ 2016-11-17 Cell www.ncbi.nlm.nih.gov/pubmed/27863252 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. Mean corpuscular hemoglobin 172,332 European ancestry individuals NA Affymetrix [~ 2500000] (imputed) 275 mean corpuscular hemoglobin http://www.ebi.ac.uk/efo/EFO_0004527 GCST004630 Genome-wide genotyping array 172332 2017-08-30 27863252 Astle WJ 2016-11-17 Cell www.ncbi.nlm.nih.gov/pubmed/27863252 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. Basophil percentage of white cells 171,996 European ancestry individuals NA Affymetrix [~ 2500000] (imputed) 65 basophil percentage of leukocytes http://www.ebi.ac.uk/efo/EFO_0007992 GCST004631 Genome-wide genotyping array 171996 2017-08-30 27863252 Astle WJ 2016-11-17 Cell www.ncbi.nlm.nih.gov/pubmed/27863252 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. Lymphocyte percentage of white cells 171,748 European ancestry individuals NA Affymetrix [~ 2500000] (imputed) 147 lymphocyte percentage of leukocytes http://www.ebi.ac.uk/efo/EFO_0007993 GCST004632 Genome-wide genotyping array 171748 2017-08-30 27863252 Astle WJ 2016-11-17 Cell www.ncbi.nlm.nih.gov/pubmed/27863252 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. Neutrophil percentage of white cells 171,542 European ancestry individuals NA Affymetrix [~ 2500000] (imputed) 135 neutrophil percentage of leukocytes http://www.ebi.ac.uk/efo/EFO_0007990 GCST004633 Genome-wide genotyping array 171542 2017-08-30 27863252 Astle WJ 2016-11-17 Cell www.ncbi.nlm.nih.gov/pubmed/27863252 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. Basophil percentage of granulocytes 170,223 European ancestry individuals NA Affymetrix [~ 2500000] (imputed) 62 basophil percentage of granulocytes http://www.ebi.ac.uk/efo/EFO_0007995 GCST004634 Genome-wide genotyping array 170223 2017-08-30 27863252 Astle WJ 2016-11-17 Cell www.ncbi.nlm.nih.gov/pubmed/27863252 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. Mean platelet volume 164,454 European ancestry individuals NA Affymetrix [~ 2500000] (imputed) 294 mean platelet volume http://www.ebi.ac.uk/efo/EFO_0004584 GCST004599 Genome-wide genotyping array 164454 2017-08-30 27863252 Astle WJ 2016-11-17 Cell www.ncbi.nlm.nih.gov/pubmed/27863252 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. Red blood cell count 172,952 European ancestry individuals NA Affymetrix [~ 2500000] (imputed) 212 erythrocyte count http://www.ebi.ac.uk/efo/EFO_0004305 GCST004601 Genome-wide genotyping array 172952 2017-08-09 28470677 Tang H 2017-05-03 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/28470677 Genetic polymorphisms associated with pancreatic cancer survival: a genome-wide association study. Survival in pancreatic cancer 868 European ancestry cases 820 European ancestry cases NR [7738399] (imputed) 61 overall survival, pancreatic carcinoma http://www.ebi.ac.uk/efo/EFO_0000638, http://www.ebi.ac.uk/efo/EFO_0002618 GCST004485 Genome-wide genotyping array 868 2017-06-29 28358823 Kim SK 2017-03-30 PLoS One www.ncbi.nlm.nih.gov/pubmed/28358823 Genome-wide association screens for Achilles tendon and ACL tears and tendinopathy. Achilles tendinopathy 4,258 European ancestry cases, 413 Latin-American cases, 268 East Asian ancestry cases, 192 African American cases, 17 South East Asian ancestry cases, 79,006 European ancestry controls, 8,147 Latin-American controls, 7,250 East Asian ancestry controls, 2,969 African American controls, 459 South East Asian ancestry controls NA Affymetrix [10551193] (imputed) 4 Tendinopathy http://www.ebi.ac.uk/efo/EFO_1001434 GCST004263 Genome-wide genotyping array 102979 2017-06-29 28358823 Kim SK 2017-03-30 PLoS One www.ncbi.nlm.nih.gov/pubmed/28358823 Genome-wide association screens for Achilles tendon and ACL tears and tendinopathy. Anterior cruciate ligament rupture 495 European ancestry cases, 54 Latin-American cases, 49 East Asian ancestry cases, 82,769 European ancestry controls, 8,506 Latin-American controls, 7,469 East Asian ancestry controls NA Affymetrix [8303052] (imputed) 3 ligament rupture http://www.ebi.ac.uk/efo/EFO_1002012 GCST004265 Genome-wide genotyping array 99342 2017-09-21 28743860 Medina-Gomez C 2017-07-25 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28743860 Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus. TB-LM or TBLH-BMD (pleiotropy) 8,327 European ancestry individuals, 2,087 individuals NA Illumina [2276811] (imputed) 12 bone density, lean body mass http://www.ebi.ac.uk/efo/EFO_0003923, http://www.ebi.ac.uk/efo/EFO_0004995 GCST004771 Genome-wide genotyping array 10414 2017-09-21 28743860 Medina-Gomez C 2017-07-25 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28743860 Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus. Lean body mass 8,327 European ancestry individuals, 2,087 individuals NA Illumina [2276811] (imputed) 1 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST004770 Genome-wide genotyping array 10414 2017-09-21 28743860 Medina-Gomez C 2017-07-25 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28743860 Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus. Bone mineral density (paediatric, total body less head) 8,327 European ancestry individuals, 2,087 individuals NA Illumina [2276811] (imputed) 10 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST004772 Genome-wide genotyping array 10414 2016-09-23 26502338 Bentham J 2015-10-26 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26502338 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus. Systemic lupus erythematosus 5,201 European ancestry cases, 9,066 European ancestry controls NA Illumina [> 644674] (imputed) 47 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST003156 Genome-wide genotyping array 14267 2016-09-23 26502338 Bentham J 2015-10-26 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26502338 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus. Systemic lupus erythematosus 5,201 European ancestry cases, 9,066 European ancestry controls 2,018 European ancestry cases, 6,925 European ancestry controls Illumina [644674] 53 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST003155 Genome-wide genotyping array 14267 2017-01-31 27436580 Cui Q 2016-07-19 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/27436580 An extended genome-wide association study identifies novel susceptibility loci for nasopharyngeal carcinoma. Nasopharyngeal carcinoma 1,583 Southern Chinese ancestry cases, 2,979 Southern Chinese ancestry controls 5,463 Southern Chinese ancestry cases, 5,591 Southern Chinese ancestry controls Illumina [463250] 6 nasopharyngeal neoplasm http://www.ebi.ac.uk/efo/EFO_0004252 GCST003578 Genome-wide genotyping array 4562 2015-05-14 22174851 Lingappa JR 2011-12-12 PLoS One www.ncbi.nlm.nih.gov/pubmed/22174851 Genomewide association study for determinants of HIV-1 acquisition and viral set point in HIV-1 serodiscordant couples with quantified virus exposure. HIV-1 viral setpoint 496 African ancestry cases NA Illumina [990115] 14 HIV viral set point measurement http://www.ebi.ac.uk/efo/EFO_0006319 GCST001352 Genome-wide genotyping array 496 2015-05-14 22174851 Lingappa JR 2011-12-12 PLoS One www.ncbi.nlm.nih.gov/pubmed/22174851 Genomewide association study for determinants of HIV-1 acquisition and viral set point in HIV-1 serodiscordant couples with quantified virus exposure. HIV-1 susceptibility 496 African ancestry cases and 302 African ancestry exposed controls from serodiscordant couples NA Illumina [990115] 9 HIV-1 infection, Susceptibility to viral and mycobacterial infections http://www.ebi.ac.uk/efo/EFO_0000180, http://www.orpha.net/ORDO/Orphanet_391311 GCST001353 Genome-wide genotyping array 798 2008-07-01 18521185 Chen WM 2008-06-04 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/18521185 Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. Fasting plasma glucose 5,088 European ancestry individuals 18,436 European ancestry individuals Illumina [315635] 1 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST000202 Genome-wide genotyping array 5088 2014-07-01 20385819 Chen W 2010-04-12 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/20385819 Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Age-related macular degeneration 2,157 European ancestry cases, 1,150 European ancestry controls 7,892 European ancestry cases, 5,998 European ancestry controls, 678 Japanese ancestry cases, 336 Japanese ancestry controls Illumina [~ 2500000] (imputed) 8 age-related macular degeneration http://www.ebi.ac.uk/efo/EFO_0001365 GCST000652 Genome-wide genotyping array 3307 2011-09-21 21827660 Yang TH 2011-08-09 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/21827660 Combinations of newly confirmed Glioma-Associated loci link regions on chromosomes 1 and 9 to increased disease risk. Glioma 781 European ancestry cases, 3,992 European ancestry controls NA Illumina [489781] 1 central nervous system cancer http://www.ebi.ac.uk/efo/EFO_0000326 GCST001194 Genome-wide genotyping array 4773 2013-06-26 23532257 Ma RC 2013-03-27 Diabetologia www.ncbi.nlm.nih.gov/pubmed/23532257 Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4. Type 2 diabetes 684 Han Chinese ancestry cases, 955 Han Chinese ancestry controls 18,954 East Asian ancestry cases, 18,029 East Asian ancestry controls, 794 Malay ancestry cases, 1,204 Malay ancestry controls, 977 Indian ancestry cases, 1,169 Indian ancestry controls, 8,130 European ancestry cases, 38,987 European ancestry controls Illumina [2925090] (imputed) 1 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST001919 Genome-wide genotyping array 1639 2015-05-08 22076464 Ellinghaus E 2011-11-11 Leukemia www.ncbi.nlm.nih.gov/pubmed/22076464 Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia. Acute lymphoblastic leukemia (childhood) 419 European ancestry ETV6-RUNX1 positive cases, 474 European ancestry controls 951 European ancestry ETV6-RUNX1 positive cases, 326 European ancestry ETV6-RUNX1 negative cases, 3,061 European ancestry controls Affymetrix [355750] 31 acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000220 GCST001320 Genome-wide genotyping array 900 2012-03-23 22344221 Okada Y 2012-02-19 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22344221 Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations. Body mass index (SNP x SNP interaction) 26,620 Japanese ancestry individuals 35,625 East Asian ancestry individuals Illumina [2178018] (imputed) 10 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST001416 Genome-wide genotyping array 26620 2014-04-10 24143190 Low SK 2013-10-15 PLoS One www.ncbi.nlm.nih.gov/pubmed/24143190 Genome-wide association study of breast cancer in the Japanese population. Breast cancer 2,642 Japanese ancestry cases, 2,099 Japanese ancestry controls 2,885 Japanese ancestry cases, 3,395 Japanese ancestry controls Illumina [5335291] (imputed) 4 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST002234 Genome-wide genotyping array 4741 2011-08-02 21668797 Agrawal A 2010-11-04 Addict Biol www.ncbi.nlm.nih.gov/pubmed/21668797 A genome-wide association study of DSM-IV cannabis dependence. Cannabis dependence 708 African American or European ancestry cases, 2,346 African American or European ancestry controls NA Illumina [948142] 10 cannabis dependence http://www.ebi.ac.uk/efo/EFO_0007191 GCST000861 Genome-wide genotyping array 3054 2012-11-28 22968431 Urban TJ 2012-09-09 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/22968431 Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs. Drug-induced liver injury 783 European ancestry cases, 3,001 European ancestry controls 307 European ancestry cases, 2,587 European ancestry controls Illumina [800769] 1 drug-induced liver injury http://www.ebi.ac.uk/efo/EFO_0004228 GCST001673 Genome-wide genotyping array 3784 2011-11-24 22020760 Won HH 2011-10-21 Cancer www.ncbi.nlm.nih.gov/pubmed/22020760 Polymorphic markers associated with severe oxaliplatin-induced, chronic peripheral neuropathy in colon cancer patients. Response to platinum-based agents 96 colon cancer cases 247 colon cancer cases Affymetrix [656843] 3 response to platinum based chemotherapy http://www.ebi.ac.uk/efo/EFO_0004647 GCST001291 Genome-wide genotyping array 96 2012-11-28 22990020 Huang J 2012-09-18 Blood www.ncbi.nlm.nih.gov/pubmed/22990020 Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. Plasminogen activator inhibitor type 1 levels (PAI-1) 19,599 European ancestry individuals 10,764 European ancestry individuals Affymetrix, Illumina [2445683] (imputed) 4 plasminogen activator inhibitor 1 measurement http://www.ebi.ac.uk/efo/EFO_0004792 GCST001684 Genome-wide genotyping array 19599 2012-11-04 22951725 Tang XF 2012-09-06 J Invest Dermatol www.ncbi.nlm.nih.gov/pubmed/22951725 Association analyses identify three susceptibility Loci for vitiligo in the Chinese Han population. Vitiligo 1,117 Han Chinese ancestry cases, 1,701 Han Chinese ancestry controls 5,740 Han Chinese ancestry cases, 10,324 Han Chinese ancestry controls Illumina [493909] 4 Vitiligo http://www.ebi.ac.uk/efo/EFO_0004208 GCST001670 Genome-wide genotyping array 2818 2012-09-25 22829776 Coviello AD 2012-07-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22829776 A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. Sex hormone-binding globulin levels 21,791 European ancestry individuals 8,175 European ancestry individuals Affymetrix, Illumina [2543887] (imputed) 30 sex hormone-binding globulin measurement http://www.ebi.ac.uk/efo/EFO_0004696 GCST001612 Genome-wide genotyping array 21791 2013-08-21 21738480 Nalls MA 2011-07-01 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21738480 Multiple loci are associated with white blood cell phenotypes. White blood cell count 19,509 European ancestry individuals 11,823 European ancestry individuals Affymetrix, Illumina [> 2400000] (imputed) 10 leukocyte count http://www.ebi.ac.uk/efo/EFO_0004308 GCST001137 Genome-wide genotyping array 19509 2014-03-25 24058526 Bhatnagar P 2013-09-13 PLoS One www.ncbi.nlm.nih.gov/pubmed/24058526 Genome-wide meta-analysis of systolic blood pressure in children with sickle cell disease. Systolic blood pressure in sickle cell anemia 1617 African American cases NA Illumina [1019297] (imputed) 10 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST002187 Genome-wide genotyping array 1617 2013-08-21 23263444 Frazier-Wood AC 2012-12-22 Hum Genet www.ncbi.nlm.nih.gov/pubmed/23263444 Genetic variants associated with VLDL, LDL and HDL particle size differ with race/ethnicity. Lipoprotein diameter 817 European ancestry individuals 2,430 European ancestry individuals, 1,594 African American individuals, 1,422 Hispanic individuals, 758 Chinese ancestry individuals Affymetrix [2543887] (imputed) 0 Bronchopulmonary dysplasia http://www.orpha.net/ORDO/Orphanet_70589 GCST001789 Genome-wide genotyping array 817 2013-02-01 23143601 Lan Q 2012-11-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23143601 Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. Lung cancer 5,510 East Asian ancestry cases, 4,544 East Asian ancestry controls 1,099 East Asian ancestry cases, 2,913 East Asian ancestry controls Illumina [596032] 7 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST001740 Genome-wide genotyping array 10054 2014-04-25 24064335 Pei YF 2013-10-08 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/24064335 Meta-analysis of genome-wide association data identifies novel susceptibility loci for obesity. Body mass index 8,463 European ancestry individuals, 7,478 African American individuals, 3,348 Hispanic individuals, 1,624 Han Chinese ancestry individuals 4,979 European ancestry individuals, 2,740 Han Chinese ancestry individuals Affymetrix, Illumina [4325550] (imputed) 3 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST002227 Genome-wide genotyping array 20913 2014-04-25 24064335 Pei YF 2013-10-08 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/24064335 Meta-analysis of genome-wide association data identifies novel susceptibility loci for obesity. Fat body mass 6,433 European ancestry individuals, 709 African American individuals, 408 Hispanic individuals, 1,622 Han Chinese ancestry individuals 4,967 European ancestry individuals, 2,740 Han Chinese ancestry individuals Affymetrix, Illumina [4325550] (imputed) 2 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST002226 Genome-wide genotyping array 9172 2008-06-16 18372901 Tenesa A 2008-03-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18372901 Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Colorectal cancer 981 European ancestry cases, 1,002 European ancestry controls 10,287 European ancestry cases, 10,401 European ancestry controls, 4,400 Japanese ancestry cases, 3,179 Japanese ancestry controls, 1,789 cases, 1,771 controls Illumina [541628] 3 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST000168 Genome-wide genotyping array 1983 2012-11-13 22935194 Connolly JJ 2012-08-30 Child Dev www.ncbi.nlm.nih.gov/pubmed/22935194 A genome-wide association study of autism incorporating autism diagnostic interview-revised, autism diagnostic observation schedule, and social responsiveness scale. Autism Up to 2,165 European, African American, East Asian and South Asian ancestry individuals Up to 1,231 individuals Illumina [522149] 0 autism http://www.ebi.ac.uk/efo/EFO_0003758 GCST001655 Genome-wide genotyping array 2165 2010-05-03 20360315 Uher R 2010-04-01 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/20360315 Genome-wide pharmacogenetics of antidepressant response in the GENDEP project. Response to antidepressants 706 European ancestry individuals NA Illumina [539391] 8 response to antidepressant http://purl.obolibrary.org/obo/GO_0036276 GCST000643 Genome-wide genotyping array 706 2010-06-14 20484958 Diergaarde B 2010-05-17 Pancreatology www.ncbi.nlm.nih.gov/pubmed/20484958 Pooling-based genome-wide association study implicates gamma-glutamyltransferase 1 (GGT1) gene in pancreatic carcinogenesis. Pancreatic cancer 97 European ancestry cases, 93 European ancestry controls 63 European ancestry cases, 79 European ancestry controls Affymetrix [> 900000] 0 pancreatic carcinoma http://www.ebi.ac.uk/efo/EFO_0002618 GCST000686 Genome-wide genotyping array 190 2014-02-11 23886662 Weidinger S 2013-07-25 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23886662 A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis. Atopic dermatitis 1563 European ancestry cases, 4,054 European ancestry controls 2,286 European ancestry cases, 3,160 European ancestry controls Illumina [2406139] (imputed) 4 atopic eczema http://www.ebi.ac.uk/efo/EFO_0000274 GCST002100 Genome-wide genotyping array 5617 2009-01-15 19056611 Timpson NJ 2008-12-03 Diabetes www.ncbi.nlm.nih.gov/pubmed/19056611 Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data. Type 2 diabetes 958 European ancestry obese cases, 955 European ancestry non-obese cases, 2,938 European ancestry controls Up to 3,757 European ancestry cases, up to 5,346 European ancestry controls Affymetrix [393453] 8 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST000277 Genome-wide genotyping array 4851 2014-12-10 24751813 Drago A 2014-06-01 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/24751813 Genome-wide association study supports the role of the immunological system and of the neurodevelopmental processes in response to haloperidol treatment. Response to haloperidol in psychosis 96 European ancestry cases NA Illumina [1080870] (imputed) 2 response to haloperidol http://purl.obolibrary.org/obo/GO_1905119 GCST002465 Genome-wide genotyping array 96 2014-12-11 24919509 Terao C 2014-06-11 J Med Genet www.ncbi.nlm.nih.gov/pubmed/24919509 A genome-wide association study of serum levels of prostate-specific antigen in the Japanese population. Prostate-specific antigen levels 1,086 Japanese ancestry males 1,302 Japanese ancestry males Illumina [303283] 2 prostate specific antigen measurement http://www.ebi.ac.uk/efo/EFO_0004624 GCST002476 Genome-wide genotyping array 1086 2015-07-15 25429064 He M 2014-11-26 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/25429064 Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. Height 36,227 East Asian ancestry individuals 57,699 East Asian ancestry individuals Affymetrix, Illumina [2704730] (imputed) 125 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST002702 Genome-wide genotyping array 36227 2015-04-16 25129146 Wu C 2014-08-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/25129146 Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations. Esophageal squamous cell carcinoma 5,337 Han Chinese ancestry cases, 5,787 Han Chinese ancestry controls 9,654 Han Chinese ancestry cases, 10,058 Han Chinese ancestry controls Affymetrix, Illumina [7556215] (imputed) 10 esophageal squamous cell carcinoma http://www.ebi.ac.uk/efo/EFO_0005922 GCST002568 Genome-wide genotyping array 11124 2014-10-23 24677629 Wolf EJ 2014-03-27 Depress Anxiety www.ncbi.nlm.nih.gov/pubmed/24677629 A genome-wide association study of clinical symptoms of dissociation in a trauma-exposed sample. Post-traumatic stress disorder 484 European ancestry trauma-exposed individuals NA Illumina [1197702] 7 post-traumatic stress disorder http://www.ebi.ac.uk/efo/EFO_0001358 GCST002401 Genome-wide genotyping array 484 2010-07-13 20585324 Dick DM 2010-06-27 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/20585324 Genome-wide association study of conduct disorder symptomatology. Conduct disorder (symptom count) 872 European, African American and other ancestry substance dependence cases, 3,091 European, African American and other ancestry controls NA Illumina [948658] 17 conduct disorder http://www.ebi.ac.uk/efo/EFO_0004216 GCST000713 Genome-wide genotyping array 3963 2010-07-13 20585324 Dick DM 2010-06-27 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/20585324 Genome-wide association study of conduct disorder symptomatology. Conduct disorder 872 European, African American and other ancestry substance dependence cases, 3,091 European, African American and other ancestry controls NA Illumina [948658] 12 conduct disorder http://www.ebi.ac.uk/efo/EFO_0004216 GCST000714 Genome-wide genotyping array 3963 2014-05-01 24163127 Figueroa JD 2013-10-24 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/24163127 Genome-wide association study identifies multiple loci associated with bladder cancer risk. Bladder cancer 6,911 European ancestry cases, 11,818 European ancestry controls 801 cases, 1,307 controls Illumina [462190] 7 bladder carcinoma http://www.ebi.ac.uk/efo/EFO_0000292 GCST002243 Genome-wide genotyping array 18729 2014-05-01 24163127 Figueroa JD 2013-10-24 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/24163127 Genome-wide association study identifies multiple loci associated with bladder cancer risk. Bladder cancer up to 2,305 European ancestry cases, up to 3,901 European ancestry controls up to 13,298 cases, up to 54,535 controls Illumina [462190] 10 bladder carcinoma http://www.ebi.ac.uk/efo/EFO_0000292 GCST002240 Genome-wide genotyping array 6206 2015-01-13 24940741 Chang SW 2014-06-18 PLoS One www.ncbi.nlm.nih.gov/pubmed/24940741 A genome-wide association study on chronic HBV infection and its clinical progression in male Han-Taiwanese. Chronic hepatitis B infection 321 Chinese ancestry cases, 304 Chinese ancestry controls 1,302 Chinese ancestry cases, 761 Chinese ancestry controls Illumina [456262] 5 chronic hepatitis B virus infection http://www.ebi.ac.uk/efo/EFO_0004239 GCST002490 Genome-wide genotyping array 625 2011-01-06 21076409 Sotoodehnia N 2010-11-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21076409 Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. QRS duration 39,717 European ancestry individuals, 690 Orcadian individuals 7,170 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 12 heart function measurement http://www.ebi.ac.uk/efo/EFO_0004311 GCST000872 Genome-wide genotyping array 40407 2014-04-10 24121790 Levine DM 2013-10-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24121790 A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus. Esophageal adenocarcinoma 1,516 European ancestry cases, 3,209 European ancestry controls 874 European ancestry cases, 6,911 European ancestry controls Illumina [922031] 8 esophageal adenocarcinoma http://www.ebi.ac.uk/efo/EFO_0000478 GCST002232 Genome-wide genotyping array 4725 2014-04-10 24121790 Levine DM 2013-10-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24121790 A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus. Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined) 3,928 European ancestry cases, 3,207 European ancestry controls 1,636 European ancestry cases, 6,911 European ancestry controls Illumina [922031] 10 esophageal adenocarcinoma, digestive system disease, Barrett's esophagus http://www.ebi.ac.uk/efo/EFO_0000478, http://www.ebi.ac.uk/efo/EFO_0000405, http://www.ebi.ac.uk/efo/EFO_0000280 GCST002231 Genome-wide genotyping array 7135 2014-04-10 24121790 Levine DM 2013-10-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24121790 A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus. Barrett's esophagus 2,416 European ancestry cases, 3,206 European ancestry controls 759 European ancestry cases, 6,911 European ancestry controls Illumina [922031] 7 Barrett's esophagus http://www.ebi.ac.uk/efo/EFO_0000280 GCST002230 Genome-wide genotyping array 5622 2010-09-24 20811658 Uhl GR 2010-08-24 Mol Med www.ncbi.nlm.nih.gov/pubmed/20811658 Genome-wide association for smoking cessation success in a trial of precessation nicotine replacement. Smoking cessation 369 European ancestry individuals NA Affymetrix [905273] 1 smoking cessation http://www.ebi.ac.uk/efo/EFO_0004319 GCST000778 Genome-wide genotyping array 369 2015-04-24 25187374 Hwang JY 2014-09-03 Diabetes www.ncbi.nlm.nih.gov/pubmed/25187374 Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians. Fasting plasma glucose 24,740 East Asian ancestry individuals 21,345 East Asian ancestry individuals Affymetrix, Illumina [up to 2315813] (imputed) 14 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST002586 Genome-wide genotyping array 24740 2014-11-12 24785509 Barnett GC 2014-04-28 Radiother Oncol www.ncbi.nlm.nih.gov/pubmed/24785509 A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity. Response to radiotherapy in cancer (late toxicity) 579 European ancestry prostate cancer cases, 1,194 European ancestry breast cancer cases 516 European ancestry prostate cancer cases, 862 prostate cancer cases, 355 breast cancer cases Illumina [2417493] (imputed) 10 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST002431 Genome-wide genotyping array 1773 2015-05-22 25343990 Cornelis MC 2014-10-24 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/25343990 Genome-wide association study of selenium concentrations. Toenail selenium levels 4,162 European ancestry individuals NA Affymetrix, Illumina [2378986] (imputed) 16 selenium measurement http://www.ebi.ac.uk/efo/EFO_0006331 GCST002671 Genome-wide genotyping array 4162 2015-07-08 25343990 Cornelis MC 2014-10-24 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/25343990 Genome-wide association study of selenium concentrations. Blood and toenail selenium levels 9,639 European ancestry individuals NA Affymetrix, Illumina [2379663] (imputed) 12 selenium measurement http://www.ebi.ac.uk/efo/EFO_0006331 GCST002670 Genome-wide genotyping array 9639 2015-04-01 25147783 Keene KL 2014-08-06 Front Public Health www.ncbi.nlm.nih.gov/pubmed/25147783 Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial. Vitamin B levels in ischemic stroke 1,725 European ancestry cases, 258 African ancestry cases, 117 cases NA Illumina [737081] 8 vitamin B measurement http://www.ebi.ac.uk/efo/EFO_0004843 GCST002559 Genome-wide genotyping array 2100 2015-09-14 25387704 Malone SM 2014-12-01 Psychophysiology www.ncbi.nlm.nih.gov/pubmed/25387704 Heritability and molecular-genetic basis of resting EEG activity: a genome-wide association study. Electroencephalogram traits 2,383 European ancestry adolescents and 1,643 European ancestry adults from 1,613 families NA Illumina [527829] 27 theta wave measurement, delta wave measurement, alpha peak frequency measurement, alpha wave measurement, electroencephalogram measurement, beta wave measurement http://www.ebi.ac.uk/efo/EFO_0006873, http://www.ebi.ac.uk/efo/EFO_0006872, http://www.ebi.ac.uk/efo/EFO_0006883, http://www.ebi.ac.uk/efo/EFO_0006870, http://www.ebi.ac.uk/efo/EFO_0004357, http://www.ebi.ac.uk/efo/EFO_0006871 GCST002709 Genome-wide genotyping array 5639 2015-06-08 25194280 Wei Q 2014-09-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/25194280 Genome-wide association study identifies three susceptibility loci for laryngeal squamous cell carcinoma in the Chinese population. Laryngeal squamous cell carcinoma 993 Chinese ancestry cases, 1,995 Chinese ancestry controls 2,398 Chinese ancestry cases, 2,804 Chinese ancestry controls Affymetrix [662108] 6 laryngeal squamous cell carcinoma http://www.ebi.ac.uk/efo/EFO_0006352 GCST002597 Genome-wide genotyping array 2988 2015-04-23 25060954 Wolber LE 2014-07-24 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/25060954 Salt-inducible kinase 3, SIK3, is a new gene associated with hearing. Hearing function 1,022 European ancestry individuals, 280 Carlantino (founder/genetic isolate) individuals, 1,097 Friuli Venezia Giulia (founder/genetic isolate) individuals, 804 Korcula (founder/genetic isolate) individuals, 497 Split (founder/genetic isolate) individuals, 421 Cilento (founder/genetic isolate) individuals, 470 Talana (founder/genetic isolate) individuals, 348 Silk Road individuals NA Affymetrix, Illumina [> 2300000] (imputed) 5 sensory perception of sound http://purl.obolibrary.org/obo/GO_0007605 GCST002543 Genome-wide genotyping array 4939 2014-03-13 23942779 McGue M 2013-08-14 Behav Genet www.ncbi.nlm.nih.gov/pubmed/23942779 A genome-wide association study of behavioral disinhibition. Nicotine use 7,188 European ancestry individuals NA Illumina [527829] 6 nicotine use http://www.ebi.ac.uk/efo/EFO_0005430 GCST002135 Genome-wide genotyping array 7188 2014-03-13 23942779 McGue M 2013-08-14 Behav Genet www.ncbi.nlm.nih.gov/pubmed/23942779 A genome-wide association study of behavioral disinhibition. Alcohol consumption 7,188 European ancestry individuals NA Illumina [527829] 2 alcohol drinking http://www.ebi.ac.uk/efo/EFO_0004329 GCST002130 Genome-wide genotyping array 7188 2014-03-13 23942779 McGue M 2013-08-14 Behav Genet www.ncbi.nlm.nih.gov/pubmed/23942779 A genome-wide association study of behavioral disinhibition. Alcohol dependence 7,188 European ancestry individuals NA Illumina [527829] 4 alcohol dependence http://www.ebi.ac.uk/efo/EFO_0003829 GCST002134 Genome-wide genotyping array 7188 2014-03-13 23942779 McGue M 2013-08-14 Behav Genet www.ncbi.nlm.nih.gov/pubmed/23942779 A genome-wide association study of behavioral disinhibition. Illicit drug use 7,188 European ancestry individuals NA Illumina [527829] 10 illegal drug consumption http://www.ebi.ac.uk/efo/EFO_0005431 GCST002133 Genome-wide genotyping array 7188 2014-03-13 23942779 McGue M 2013-08-14 Behav Genet www.ncbi.nlm.nih.gov/pubmed/23942779 A genome-wide association study of behavioral disinhibition. Non-substance related behavioral disinhibition 7,188 European ancestry individuals NA Illumina [527829] 4 non-substance related disinhibited behaviour http://www.ebi.ac.uk/efo/EFO_0005432 GCST002132 Genome-wide genotyping array 7188 2014-03-13 23942779 McGue M 2013-08-14 Behav Genet www.ncbi.nlm.nih.gov/pubmed/23942779 A genome-wide association study of behavioral disinhibition. Behavioural disinhibition (generation interaction) 3,852 European ancestry parents, 3,336 European ancestry offspring NA Illumina [527829] 20 nicotine use, generational effect measurement, illegal drug consumption, non-substance related disinhibited behaviour, alcohol drinking, alcohol dependence http://www.ebi.ac.uk/efo/EFO_0005430, http://www.ebi.ac.uk/efo/EFO_0008364, http://www.ebi.ac.uk/efo/EFO_0005431, http://www.ebi.ac.uk/efo/EFO_0005432, http://www.ebi.ac.uk/efo/EFO_0004329, http://www.ebi.ac.uk/efo/EFO_0003829 GCST002131 Genome-wide genotyping array 7188 2014-03-14 23969696 Sabater-Lleal M 2013-08-22 Circulation www.ncbi.nlm.nih.gov/pubmed/23969696 Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Fibrinogen 91,323 European ancestry individuals 8,423 African American individuals, 1,447 Hispanic individuals Affymetrix, Illumina [2515567] (imputed) 24 fibrinogen measurement http://www.ebi.ac.uk/efo/EFO_0004623 GCST002147 Genome-wide genotyping array 91323 2014-11-21 24825563 McDonald ML 2014-05-13 Am J Respir Cell Mol Biol www.ncbi.nlm.nih.gov/pubmed/24825563 Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease. Resting oxygen saturation in chronic osbtructive pulmonary disease (pulse oxymetry) 820 African American cases 4,568 European ancestry cases Illumina [6160662] (imputed) 2 oxygen saturation measurement http://www.ebi.ac.uk/efo/EFO_0005682 GCST002447 Genome-wide genotyping array 820 2009-02-28 19221038 Soranzo N 2009-02-12 Blood www.ncbi.nlm.nih.gov/pubmed/19221038 A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function. Mean platelet volume 1,221 individuals 7,365 individuals Affymetrix [361352] 1 mean platelet volume http://www.ebi.ac.uk/efo/EFO_0004584 GCST000342 Genome-wide genotyping array 1221 2014-12-14 24927181 Navarini AA 2014-06-13 Nat Commun www.ncbi.nlm.nih.gov/pubmed/24927181 Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. Acne (severe) 1,893 European ancestry cases, 5,132 European ancestry controls 2,063 European ancestry cases, 1,970 European ancestry controls Illumina [7300000] (imputed) 14 acne http://www.ebi.ac.uk/efo/EFO_0003894 GCST002481 Genome-wide genotyping array 7025 2014-10-01 24399259 He L 2014-01-07 Nat Commun www.ncbi.nlm.nih.gov/pubmed/24399259 Two new susceptibility loci 1q24.2 and 11p11.2 confer risk to severe acne. Acne (severe) 1,031 Han Chinese ancestry cases, 1,031 Han Chinese ancestry controls 1,860 Han Chinese ancestry cases, 3,660 Han Chinese ancestry controls Illumina [809305] 3 acne http://www.ebi.ac.uk/efo/EFO_0003894 GCST002329 Genome-wide genotyping array 2062 2014-12-10 24892410 Leu HB 2014-06-03 PLoS One www.ncbi.nlm.nih.gov/pubmed/24892410 A novel SNP associated with nighttime pulse pressure in young-onset hypertension patients could be a genetic prognostic factor for cardiovascular events in a general cohort in Taiwan. Pulse pressure in young-onset hypertension 382 individuals 559 individuals Illumina [560186] 1 pulse pressure measurement http://www.ebi.ac.uk/efo/EFO_0005763 GCST002470 Genome-wide genotyping array 382 2014-10-28 24665060 Argos M 2014-03-24 J Med Genet www.ncbi.nlm.nih.gov/pubmed/24665060 Genome-wide association study of smoking behaviours among Bangladeshi adults. Smoking quantity 1,837 Bangladeshi ancestry males, 198 Bangladeshi ancestry females NA Illumina [1211988] (imputed) 8 smoking behaviour measurement http://www.ebi.ac.uk/efo/EFO_0005671 GCST002393 Genome-wide genotyping array 2035 2014-10-28 24665060 Argos M 2014-03-24 J Med Genet www.ncbi.nlm.nih.gov/pubmed/24665060 Genome-wide association study of smoking behaviours among Bangladeshi adults. Smoking initiation 754 Bangladeshi ancestry never smoker males, 2,565 Bangladeshi ancestry never smoker females, 1,837 Bangladeshi ancestry ever smoker males, 198 Bangladeshi ancestry ever smoker females NA Illumina [1211988] (imputed) 27 smoking initiation http://www.ebi.ac.uk/efo/EFO_0005670 GCST002396 Genome-wide genotyping array 5354 2014-10-28 24665060 Argos M 2014-03-24 J Med Genet www.ncbi.nlm.nih.gov/pubmed/24665060 Genome-wide association study of smoking behaviours among Bangladeshi adults. Age of smoking initiation 1,837 Bangladeshi ancestry males, 198 Bangladeshi ancestry females NA Illumina [1211988] (imputed) 8 age at onset, smoking initiation http://www.ebi.ac.uk/efo/EFO_0004847, http://www.ebi.ac.uk/efo/EFO_0005670 GCST002394 Genome-wide genotyping array 2035 2014-10-28 24665060 Argos M 2014-03-24 J Med Genet www.ncbi.nlm.nih.gov/pubmed/24665060 Genome-wide association study of smoking behaviours among Bangladeshi adults. Smoking cessation 366 Bangladeshi ancestry former smoker males, 87 Bangladeshi ancestry former smoker females, 1,471 Bangladeshi ancestry current smoker males, 111 Bangladeshi ancestry current smoker females NA Illumina [1211988] (imputed) 4 smoking cessation http://www.ebi.ac.uk/efo/EFO_0004319 GCST002395 Genome-wide genotyping array 2035 2014-10-01 24489884 Mick E 2014-01-01 PLoS One www.ncbi.nlm.nih.gov/pubmed/24489884 Genome-wide association study of proneness to anger. Anger 8,747 European ancestry individuals NA Affymetrix [677643] 14 aggressive behavior http://www.ebi.ac.uk/efo/EFO_0003015 GCST002324 Genome-wide genotyping array 8747 2015-06-23 25249183 Lu X 2014-09-23 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/25249183 Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension. Systolic blood pressure 11,816 Han Chinese ancestry individuals 69,146 Han Chinese ancestry individuals Affymetrix, Illumina [2485448] (imputed) 15 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST002630 Genome-wide genotyping array 11816 2015-06-23 25249183 Lu X 2014-09-23 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/25249183 Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension. Diastolic blood pressure 11,816 Han Chinese ancestry individuals 69,146 Han Chinese ancestry individuals Affymetrix, Illumina [2485448] (imputed) 14 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST002631 Genome-wide genotyping array 11816 2015-06-23 25249183 Lu X 2014-09-23 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/25249183 Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension. Hypertension 5,065 Han Chinese ancestry cases, 4,404 Han Chinese ancestry controls 29,799 Han Chinese ancestry cases, 39,347 Han Chinese ancestry controls Affymetrix, Illumina [2485448] (imputed) 12 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST002627 Genome-wide genotyping array 9469 2015-07-07 25281659 van der Valk RJ 2014-10-03 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/25281659 A novel common variant in DCST2 is associated with length in early life and height in adulthood. Birth length 28,459 European ancestry individuals 16,145 European ancestry individuals, 280 Moroccan ancestry individuals, 284 Surinamese ancestry individuals, 319 Turkish ancestry individuals, 651 Chinese ancestry individuals Affymetrix, Illumina [2201971] (imputed) 6 body height at birth http://www.ebi.ac.uk/efo/EFO_0006784 GCST002644 Genome-wide genotyping array 28459 2015-07-07 25281659 van der Valk RJ 2014-10-03 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/25281659 A novel common variant in DCST2 is associated with length in early life and height in adulthood. Infant length 28,238 European ancestry individuals NA Affymetrix, Illumina [2193675] (imputed) 15 infant body height http://www.ebi.ac.uk/efo/EFO_0006785 GCST002646 Genome-wide genotyping array 28238 2015-07-07 25409777 Thyagarajan B 2014-11-01 Respir Res www.ncbi.nlm.nih.gov/pubmed/25409777 Genetic variants associated with lung function: the long life family study. Pulmonary function 3,889 European ancestry individuals 48,201 individuals Illumina [6522421] (imputed) 0 pulmonary function measurement http://www.ebi.ac.uk/efo/EFO_0003892 GCST002683 Genome-wide genotyping array 3889 2015-05-18 24141364 Perez-Andreu V 2013-10-20 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24141364 Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse. Acute lymphoblastic leukemia (childhood) 75 European, Asian, African American, and Hispanic ancestry Ph-like ALL cases, 436 European, Asian, African American, and Hispanic ancestry non Ph-like ALL cases, 6,661 European, Asian, African American, and Hispanic ancestry non-ALL controls 32 European, Asian, African American, and Hispanic ancestry Ph-like ALL cases, 139 European, Asian, African American, and Hispanic ancestry non Ph-like ALL cases, 3,647 European ancestry non-ALL controls, 1,228 African American non-ALL controls, 920 Hispanic non-ALL controls, 25 Native American non-ALL controls Affymetrix [up to 761049] 0 acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000220 GCST002236 Genome-wide genotyping array 7172 2014-11-01 24651765 Williams SR 2014-03-20 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/24651765 Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke. Plasma homocysteine levels (post-methionine load test) 2,710 European and other ancestry individuals, 1,725 European ancestry individuals, 258 African ancestry individuals, 117 individuals NA Affymetrix, Illumina [up to 11000000] (imputed) 5 homocysteine measurement http://www.ebi.ac.uk/efo/EFO_0004578 GCST002391 Genome-wide genotyping array 4810 2015-06-05 25240745 Lopez S 2014-09-18 Mitochondrion www.ncbi.nlm.nih.gov/pubmed/25240745 A genome-wide association study in the genetic analysis of idiopathic thrombophilia project suggests sex-specific regulation of mitochondrial DNA levels. Mitochondrial DNA levels 173 European ancestry males and 213 European ancestry females from 21 families NA Illumina [283437] 21 mitochondrial DNA measurement http://www.ebi.ac.uk/efo/EFO_0006312 GCST002616 Genome-wide genotyping array 407 2015-07-24 25436638 Malinowski JR 2014-12-01 PLoS One www.ncbi.nlm.nih.gov/pubmed/25436638 Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network. Serum thyroid-stimulating hormone levels 4,501 European ancestry individuals, 351 African American individuals NA Illumina [up to 905285] 18 thyroid stimulating hormone measurement http://www.ebi.ac.uk/efo/EFO_0004748 GCST002707 Genome-wide genotyping array 4852 2014-10-15 24574247 Yuan H 2014-02-25 Autism Res www.ncbi.nlm.nih.gov/pubmed/24574247 Investigation of maternal genotype effects in autism by genome-wide association. Maternal genotype effects in autism spectrum disorder families 561 European, African American, Asian and other ancestry mothers of autism cases, 547 European, African American, Asian and other ancestry fathers of autism cases, 508 European ancestry females 982 European and other ancestry mothers of autism cases, 1,007 European and other ancestry fathers of autism cases, 743 European and other ancestry females Illumina [1776310] (imputed) 0 autism spectrum disorder, genetic variation http://www.ebi.ac.uk/efo/EFO_0003756, http://www.ebi.ac.uk/efo/EFO_0004828 GCST002368 Genome-wide genotyping array 1616 2014-10-09 24465431 Ma RC 2014-01-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/24465431 Familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of DACH1 in Chinese. Type 2 diabetes (young onset) and obesity 99 Chinese ancestry cases, 101 Chinese ancestry controls NA Illumina [425513] 2 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST002339 Genome-wide genotyping array 200 2014-10-17 24621683 Cho MH 2014-02-07 Lancet Respir Med www.ncbi.nlm.nih.gov/pubmed/24621683 Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis. Chronic obstructive pulmonary disease (moderate to severe) 5,812 European ancestry cases, 3,955 European ancestry controls, 821 African American cases, 1,749 African American controls 2,651 cases and their relatives Illumina [up to 701491] (imputed) 9 chronic obstructive pulmonary disease http://www.ebi.ac.uk/efo/EFO_0000341 GCST002351 Genome-wide genotyping array 12337 2014-10-17 24621683 Cho MH 2014-02-07 Lancet Respir Med www.ncbi.nlm.nih.gov/pubmed/24621683 Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis. Chronic obstructive pulmonary disease (severe) 3,145 European ancestry cases, 3,955 European ancestry controls, 352 African American cases, 1,749 African American controls 2,651 cases and their relatives Illumina [up to 701491] (imputed) 6 chronic obstructive pulmonary disease http://www.ebi.ac.uk/efo/EFO_0000341 GCST002350 Genome-wide genotyping array 9201 2014-10-14 24839885 Benke KS 2014-02-19 J Am Acad Child Adolesc Psychiatry www.ncbi.nlm.nih.gov/pubmed/24839885 A genome-wide association meta-analysis of preschool internalizing problems. Preschool internalizing problems 3,121 European ancestry individuals, 1,475 children from 1,031 families NA Affymetrix, Illumina [2403520] (imputed) 13 Child Behaviour Checklist assessment http://www.ebi.ac.uk/efo/EFO_0005661 GCST002362 Genome-wide genotyping array 5627 2015-04-02 25006744 Castaldi PJ 2014-07-09 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/25006744 Genome-wide association identifies regulatory Loci associated with distinct local histogram emphysema patterns. Local histogram emphysema pattern 3,732 European ancestry smoker individuals, 2,724 European ancestry chronic obstructive pulmonary disease smoker cases, 2,372 African American smoker individuals, 786 African American chronic obstructive pulmonary disease smoker cases NA Illumina [6942916] (imputed) 25 emphysema pattern measurement http://www.ebi.ac.uk/efo/EFO_0005850 GCST002525 Genome-wide genotyping array 9614 2014-12-10 25015694 Kolek MJ 2014-06-06 Am J Cardiol www.ncbi.nlm.nih.gov/pubmed/25015694 A genome-wide association study to identify genomic modulators of rate control therapy in patients with atrial fibrillation. Response to rate control therapy in atrial fibrillation 95 non-responders, 190 responders 130 non-responders, 157 responders Illumina [6100000] (imputed) 0 response to rate control therapy http://www.ebi.ac.uk/efo/EFO_0005768 GCST002473 Genome-wide genotyping array 285 2014-04-26 24165912 He J 2013-10-28 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/24165912 Genome-wide association study identifies 8 novel loci associated with blood pressure responses to interventions in Han Chinese. Blood pressure measurement (cold pressor test) 1,881 Han Chinese ancestry individuals 698 Han Chinese ancestry individuals Affymetrix [2216774] (imputed) 7 blood pressure, response to cold pressor test http://www.ebi.ac.uk/efo/EFO_0004325, http://www.ebi.ac.uk/efo/EFO_0005404 GCST002247 Genome-wide genotyping array 1881 2014-04-26 24165912 He J 2013-10-28 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/24165912 Genome-wide association study identifies 8 novel loci associated with blood pressure responses to interventions in Han Chinese. Blood pressure measurement (high sodium and potassium intervention) 1,836 Han Chinese ancestry individuals 654 Han Chinese ancestry individuals Affymetrix [2216774] (imputed) 13 blood pressure, response to high sodium diet, response to dietary potassium supplementation http://www.ebi.ac.uk/efo/EFO_0004325, http://www.ebi.ac.uk/efo/EFO_0005401, http://www.ebi.ac.uk/efo/EFO_0005403 GCST002252 Genome-wide genotyping array 1836 2014-04-26 24165912 He J 2013-10-28 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/24165912 Genome-wide association study identifies 8 novel loci associated with blood pressure responses to interventions in Han Chinese. Blood pressure measurement (low sodium intervention) 1,850 Han Chinese ancestry individuals 660 Han Chinese ancestry individuals Affymetrix [2216774] (imputed) 10 blood pressure, response to low sodium diet http://www.ebi.ac.uk/efo/EFO_0004325, http://www.ebi.ac.uk/efo/EFO_0005402 GCST002250 Genome-wide genotyping array 1850 2014-04-26 24165912 He J 2013-10-28 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/24165912 Genome-wide association study identifies 8 novel loci associated with blood pressure responses to interventions in Han Chinese. Blood pressure measurement (high sodium intervention) 1,840 Han Chinese ancestry individuals 659 Han Chinese ancestry individuals Affymetrix [2216774] (imputed) 11 blood pressure, response to high sodium diet http://www.ebi.ac.uk/efo/EFO_0004325, http://www.ebi.ac.uk/efo/EFO_0005401 GCST002249 Genome-wide genotyping array 1840 2014-03-01 23836404 Shulman JM 2013-09-01 JAMA Neurol www.ncbi.nlm.nih.gov/pubmed/23836404 Genetic susceptibility for Alzheimer disease neuritic plaque pathology. Alzheimer's disease (neuritic plaque pathology) 651 European and unknown ancestry individuals 114 individuals Affymetrix [2465581] (imputed) 0 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST002161 Genome-wide genotyping array 651 2012-01-18 22158537 Cho YS 2011-12-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22158537 Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Type 2 diabetes 5,999 East Asian ancestry cases, 9,001 East Asian ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 159 Filipino ancestry cases, 1,624 Filipino ancestry controls 18,127 East Asian ancestry cases, 17,746 East Asian ancestry controls Affymetrix, Illumina [2626356] (imputed) 10 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST001351 Genome-wide genotyping array 18817 2010-06-13 20453842 Stahl EA 2010-05-09 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20453842 Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Rheumatoid arthritis 5,539 European ancestry cases, 20,169 European ancestry controls 6,768 European ancestry cases, 8,806 European ancestry controls Affymetrix, Illumina [~ 2716259] (imputed) 29 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST000679 Genome-wide genotyping array 25708 2012-02-24 22245343 Meda SA 2012-01-08 Neuroimage www.ncbi.nlm.nih.gov/pubmed/22245343 A large scale multivariate parallel ICA method reveals novel imaging-genetic relationships for Alzheimer's disease in the ADNI cohort. Alzheimer's disease 367 European ancestry individuals with mild cognitive impairment, 181 European ancestry individuals with mild early-stage LOAD, 209 European ancestry controls NA Illumina [533872] 2 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST001372 Genome-wide genotyping array 757 2011-06-29 21665993 Han S 2011-06-10 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21665993 Association of variants in FRAP1 and PDGFRA with corneal curvature in Asian populations from Singapore. Corneal curvature 2,008 Chinese ancestry inidividuals, 2,281 Malay ancestry individuals 2,142 Asian Indian ancestry individuals, 929 Chinese ancestry children Illumina [462291] 2 corneal topography http://www.ebi.ac.uk/efo/EFO_0004345 GCST001101 Genome-wide genotyping array 4289 2015-04-16 21844884 Wheeler HE 2011-08-16 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/21844884 Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations. Response to platinum-based chemotherapy (carboplatin) 176 Sub-Saharan African ancestry lymphoblastoid cell lines, 83 African ancestry lymphoblastoid cell lines, 175 East Asian ancestry lymphoblastoid cell lines, 174 European ancestry lymphoblastoid cell lines NA NR [~ 3000000] (imputed) 18 response to carboplatin http://purl.obolibrary.org/obo/GO_0097328 GCST001204 Genome-wide genotyping array 608 2015-04-16 21844884 Wheeler HE 2011-08-16 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/21844884 Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations. Response to platinum-based chemotherapy (cisplatin) 176 Sub-Saharan African ancestry lymphoblastoid cell lines, 83 African ancestry lymphoblastoid cell lines, 175 East Asian ancestry lymphoblastoid cell lines, 174 European ancestry lymphoblastoid cell lines NA NR [~ 3000000] (imputed) 21 response to cisplatin http://purl.obolibrary.org/obo/GO_0072718 GCST001201 Genome-wide genotyping array 608 2013-11-20 23728934 Yang L 2013-05-31 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/23728934 Polygenic transmission and complex neuro developmental network for attention deficit hyperactivity disorder: genome-wide association study of both common and rare variants. Attention deficit hyperactivity disorder 1,040 Han Chinese ancestry cases, 963 Han Chinese ancestry controls NA Affymetrix [656051] 4 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST002048 Genome-wide genotyping array 2003 2013-04-05 23300701 Jiao S 2012-12-26 PLoS One www.ncbi.nlm.nih.gov/pubmed/23300701 Genome-wide search for gene-gene interactions in colorectal cancer. Colorectal cancer (SNP x SNP interaction) 8,380 European ancestry cases, 10,558 European ancestry controls 2,527 European ancestry cases, 2,628 European ancestry controls Illumina [2011668] 7 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST001794 Genome-wide genotyping array 18938 2010-03-26 20231535 Smith NL 2010-03-15 Circulation www.ncbi.nlm.nih.gov/pubmed/20231535 Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. Factor VIII levels 15,279 European ancestry individuals up to 7,604 European ancestry individuals Affymetrix, Illumina [2729294] (imputed) 2 factor VIII measurement http://www.ebi.ac.uk/efo/EFO_0004630 GCST000626 Genome-wide genotyping array 15279 2016-04-01 20231535 Smith NL 2010-03-15 Circulation www.ncbi.nlm.nih.gov/pubmed/20231535 Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. Factor VII levels 15,422 European ancestry individuals Up to 7,604 European ancestry individuals Affymetrix, Illumina [2734954] (imputed) 2 factor VII measurement http://www.ebi.ac.uk/efo/EFO_0004619 GCST000625 Genome-wide genotyping array 15422 2016-04-01 20231535 Smith NL 2010-03-15 Circulation www.ncbi.nlm.nih.gov/pubmed/20231535 Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. vWF levels 17,596 European ancestry individuals Up to 7,604 European ancestry individuals Affymetrix, Illumina [2742821] (imputed) 4 von Willebrand factor measurement http://www.ebi.ac.uk/efo/EFO_0004629 GCST000627 Genome-wide genotyping array 17596 2014-07-23 24262325 Dichgans M 2013-11-21 Stroke www.ncbi.nlm.nih.gov/pubmed/24262325 Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. Coronary artery disease 33,398 cases, 75,726 controls NA Illumina [575000] (imputed) 23 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST002289 Genome-wide genotyping array 109124 2014-07-23 24262325 Dichgans M 2013-11-21 Stroke www.ncbi.nlm.nih.gov/pubmed/24262325 Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. Ischemic stroke 12,389 cases, 62,004 controls NA Affymetrix, Illumina [~ 2500000] (imputed) 6 stroke http://www.ebi.ac.uk/efo/EFO_0000712 GCST002286 Genome-wide genotyping array 74393 2014-07-23 24262325 Dichgans M 2013-11-21 Stroke www.ncbi.nlm.nih.gov/pubmed/24262325 Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. Large artery stroke 2,167 cases, 49,159 controls NA Affymetrix, Illumina [~ 2400000] (imputed) 9 large artery stroke http://www.ebi.ac.uk/efo/EFO_0005524 GCST002288 Genome-wide genotyping array 51326 2014-07-23 24262325 Dichgans M 2013-11-21 Stroke www.ncbi.nlm.nih.gov/pubmed/24262325 Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. Coronary artery disease or ischemic stroke 12,389 Ischemic stroke cases, 22,233 Coronary artery disease cases, ~ 88,766 controls NA Affymetrix, Illumina [up to 2500000] (imputed) 14 stroke, coronary artery disease http://www.ebi.ac.uk/efo/EFO_0000712, http://www.ebi.ac.uk/efo/EFO_0001645 GCST002287 Genome-wide genotyping array 123388 2014-07-23 24262325 Dichgans M 2013-11-21 Stroke www.ncbi.nlm.nih.gov/pubmed/24262325 Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. Coronary artery disease or large artery stroke 2,167 Large artery stroke cases, 22,233 Coronary artery disease cases, ~ 75,921 controls NA Affymetrix, Illumina [up to 2500000] (imputed) 17 large artery stroke, coronary artery disease http://www.ebi.ac.uk/efo/EFO_0005524, http://www.ebi.ac.uk/efo/EFO_0001645 GCST002290 Genome-wide genotyping array 100321 2013-11-07 23666239 Chung CC 2013-05-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23666239 Meta-analysis identifies four new loci associated with testicular germ cell tumor. Testicular germ cell tumor 582 European ancestry male cases, 1,056 European ancestry male controls 3,560 European ancestry male cases, 8,510 European ancestry male controls Illumina [NR] 11 testicular carcinoma http://www.ebi.ac.uk/efo/EFO_0005088 GCST002023 Genome-wide genotyping array 1638 2012-07-19 22673310 Liao M 2012-07-07 Genes Immun www.ncbi.nlm.nih.gov/pubmed/22673310 Genome-wide association study identifies common variants at TNFRSF13B associated with IgG level in a healthy Chinese male population. IgG levels 1,999 Chinese ancestry male individuals 1,496 Chinese ancestry male individuals Illumina [1940243] (imputed) 1 serum IgG measurement http://www.ebi.ac.uk/efo/EFO_0004565 GCST001600 Genome-wide genotyping array 1999 2012-09-27 22808956 Lyons PA 2012-07-19 N Engl J Med www.ncbi.nlm.nih.gov/pubmed/22808956 Genetically distinct subsets within ANCA-associated vasculitis. Antineutrophil cytoplasmic antibody-associated vasculitis 914 European ancestry cases, 5,259 European ancestry controls 1,454 European ancestry cases, 1,666 European ancestry controls Affymetrix [NR] 18 anti-neutrophil antibody associated vasculitis http://www.ebi.ac.uk/efo/EFO_0004826 GCST001613 Genome-wide genotyping array 6173 2013-01-23 23142968 Betcheva ET 2012-11-07 Psychiatr Genet www.ncbi.nlm.nih.gov/pubmed/23142968 Whole-genome-wide association study in the Bulgarian population reveals HHAT as schizophrenia susceptibility gene. Schizophrenia 188 European ancestry cases, 376 European ancestry controls 99 European ancestry cases, 328 European ancestry controls Illumina [495089] 1 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST001733 Genome-wide genotyping array 564 2010-09-22 20711174 Hor H 2010-08-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20711174 Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy. Narcolepsy 562 European ancestry cases, 702 European ancestry controls 370 cases, 495 controls Affymetrix [392949] 2 narcolepsy with cataplexy http://www.ebi.ac.uk/efo/EFO_0000614 GCST000771 Genome-wide genotyping array 1264 2010-09-10 20657596 Johansen CT 2010-07-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20657596 Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia. Hypertriglyceridemia 463 European ancestry cases, 1,197 European ancestry controls NA Affymetrix [~ 2100000] (imputed) 5 Hypertriglyceridemia http://www.ebi.ac.uk/efo/EFO_0004211 GCST000737 Genome-wide genotyping array 1660 2013-02-14 23192594 Velez Edwards DR 2012-11-29 Hum Genet www.ncbi.nlm.nih.gov/pubmed/23192594 Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study. Waist-to-hip circumference ratio (ever vs never smoking interaction) 8,203 African American females, 3,484 Hispanic females NA Affymetrix [706791] 3 smoking behaviour measurement, waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0005671, http://www.ebi.ac.uk/efo/EFO_0004343 GCST001754 Genome-wide genotyping array 11687 2013-02-14 23192594 Velez Edwards DR 2012-11-29 Hum Genet www.ncbi.nlm.nih.gov/pubmed/23192594 Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study. Body mass index (alcohol intake interaction) 8,203 African American females, 3,484 Hispanic females NA Affymetrix [706791] 3 alcohol consumption measurement, body mass index http://www.ebi.ac.uk/efo/EFO_0007878, http://www.ebi.ac.uk/efo/EFO_0004340 GCST001753 Genome-wide genotyping array 11687 2017-08-24 23192594 Velez Edwards DR 2012-11-29 Hum Genet www.ncbi.nlm.nih.gov/pubmed/23192594 Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study. Body mass index (dietary energy interaction) 8,203 African American females, 3,484 Hispanic females NA Affymetrix [706791] 3 diet measurement, body mass index http://www.ebi.ac.uk/efo/EFO_0008111, http://www.ebi.ac.uk/efo/EFO_0004340 GCST004587 Genome-wide genotyping array 11687 2017-08-23 23192594 Velez Edwards DR 2012-11-29 Hum Genet www.ncbi.nlm.nih.gov/pubmed/23192594 Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study. Body mass index (recreational physical activity interaction) 8,203 African American females, 3,484 Hispanic females NA Affymetrix [706791] 3 physical activity measurement, body mass index http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004340 GCST004580 Genome-wide genotyping array 11687 2017-08-24 23192594 Velez Edwards DR 2012-11-29 Hum Genet www.ncbi.nlm.nih.gov/pubmed/23192594 Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study. Body mass index (ever vs never smoking interaction) 8,203 African American females, 3,484 Hispanic females NA Affymetrix [706791] 3 smoking behaviour measurement, body mass index http://www.ebi.ac.uk/efo/EFO_0005671, http://www.ebi.ac.uk/efo/EFO_0004340 GCST004586 Genome-wide genotyping array 11687 2017-08-23 23192594 Velez Edwards DR 2012-11-29 Hum Genet www.ncbi.nlm.nih.gov/pubmed/23192594 Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study. Body mass index (smoking years interaction) 8,203 African American females, 3,484 Hispanic females NA Affymetrix [706791] 3 smoking behaviour measurement, body mass index http://www.ebi.ac.uk/efo/EFO_0005671, http://www.ebi.ac.uk/efo/EFO_0004340 GCST004581 Genome-wide genotyping array 11687 2017-08-23 23192594 Velez Edwards DR 2012-11-29 Hum Genet www.ncbi.nlm.nih.gov/pubmed/23192594 Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study. Waist-to-hip circumference ratio (dietary energy interaction) 8,203 African American females, 3,484 Hispanic females NA Affymetrix [706791] 3 diet measurement, waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0008111, http://www.ebi.ac.uk/efo/EFO_0004343 GCST004582 Genome-wide genotyping array 11687 2017-08-23 23192594 Velez Edwards DR 2012-11-29 Hum Genet www.ncbi.nlm.nih.gov/pubmed/23192594 Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study. Waist-to-hip circumference ratio (smoking years interaction) 8,203 African American females, 3,484 Hispanic females NA Affymetrix [706791] 3 smoking behaviour measurement, waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0005671, http://www.ebi.ac.uk/efo/EFO_0004343 GCST004584 Genome-wide genotyping array 11687 2017-08-23 23192594 Velez Edwards DR 2012-11-29 Hum Genet www.ncbi.nlm.nih.gov/pubmed/23192594 Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study. Waist-to-hip circumference ratio (recreational physical activity interaction) 8,203 African American females, 3,484 Hispanic females NA Affymetrix [706791] 2 physical activity measurement, waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004343 GCST004583 Genome-wide genotyping array 11687 2017-08-23 23192594 Velez Edwards DR 2012-11-29 Hum Genet www.ncbi.nlm.nih.gov/pubmed/23192594 Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study. Waist-to-hip circumference ratio (alcohol intake interaction) 8,203 African American females, 3,484 Hispanic females NA Affymetrix [706791] 3 alcohol consumption measurement, waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007878, http://www.ebi.ac.uk/efo/EFO_0004343 GCST004579 Genome-wide genotyping array 11687 2014-01-09 23817569 Hinds DA 2013-06-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23817569 A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. Self-reported allergy 53,862 European ancestry individuals NA Illumina [2400000] (imputed) 35 allergy http://www.ebi.ac.uk/efo/EFO_0003785 GCST002083 Genome-wide genotyping array 53862 2012-03-30 22354554 Thompson SD 2012-02-21 Arthritis Rheum www.ncbi.nlm.nih.gov/pubmed/22354554 Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13. Arthritis (juvenile idiopathic) 814 European ancestry cases, 658 European ancestry controls, 2,400 controls 1,744 European ancestry cases, 7,010 European ancestry controls Affymetrix [561137] 4 juvenile idiopathic arthritis http://www.ebi.ac.uk/efo/EFO_0002609 GCST001417 Genome-wide genotyping array 3872 2011-12-14 22064162 Edwards AC 2011-11-05 Psychiatr Genet www.ncbi.nlm.nih.gov/pubmed/22064162 Genome-wide association study of comorbid depressive syndrome and alcohol dependence. Depression and alcohol dependence 467 European ancestry cases, 407 European ancestry controls NA Illumina [876476] 8 alcohol dependence http://www.ebi.ac.uk/efo/EFO_0003829 GCST001313 Genome-wide genotyping array 874 2012-03-08 22319020 Davies RW 2012-02-07 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/22319020 A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex. Coronary heart disease 7,123 European ancestry cases, 6,826 European ancestry controls 5,211 European ancestry cases, 5,821 European ancestry controls Affymetrix [~ 5000000] (imputed) 5 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST001401 Genome-wide genotyping array 13949 2011-05-27 21533022 Duncan EL 2011-04-21 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21533022 Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk. Bone mineral density 900 European ancestry female individuals with low hip bone mineral density, 1,055 European ancestry female individuals with high hip bone mineral density 20,898 European ancestry female individuals Illumina [2543887] (imputed) 9 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST001050 Genome-wide genotyping array 1955 2011-10-19 21926972 Sklar P 2011-09-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21926972 Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Bipolar disorder 7,481 European ancestry cases, 9,250 European ancestry controls 4,496 European ancestry cases, 42,422 European ancestry controls Affymetrix, Illumina [2415422] (imputed) 18 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST001241 Genome-wide genotyping array 16731 2012-11-30 22976474 Siddiq A 2012-09-13 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22976474 A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11. Breast cancer 3,666 European ancestry cases, 28,864 European ancestry controls, 1,004 African American cases, 2,744 African American controls 562 European ancestry cases, 6,410 European ancestry controls, 84 Japanese ancestry cases, 830 Japanese ancestry controls, 300 Latino cases, 1,164 Latino controls Illumina [2608509] (imputed) 4 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST001683 Genome-wide genotyping array 36278 2013-11-15 23746317 Yamaguchi T 2013-05-23 Oral Dis www.ncbi.nlm.nih.gov/pubmed/23746317 Genome-wide association study of degenerative bony changes of the temporomandibular joint. Temporomandibular joint disorder 146 East Asian ancestry cases, 374 East Asian ancestry controls NA Illumina [532935] 1 temporomandibular joint disorder http://www.ebi.ac.uk/efo/EFO_0005279 GCST002029 Genome-wide genotyping array 520 2010-04-02 20228799 McGovern DP 2010-03-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20228799 Genome-wide association identifies multiple ulcerative colitis susceptibility loci. Ulcerative colitis 2,693 European ancestry cases, 6,791 European ancestry controls 2,009 European ancestry cases, 1,580 European ancestry controls Illumina [266047] 21 ulcerative colitis http://www.ebi.ac.uk/efo/EFO_0000729 GCST000624 Genome-wide genotyping array 9484 2010-03-30 20208534 Rothenberg ME 2010-03-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20208534 Common variants at 5q22 associate with pediatric eosinophilic esophagitis. Eosinophilic esophagitis (pediatric) 181 European ancestry cases, 1,974 European ancestry controls 170 European ancestry cases, 1,130 European ancestry controls Illumina [~ 550000] 14 eosinophilic esophagitis http://www.ebi.ac.uk/efo/EFO_0004232 GCST000620 Genome-wide genotyping array 2155 2010-03-15 20173747 Ellinor PT 2010-02-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20173747 Common variants in KCNN3 are associated with lone atrial fibrillation. Atrial fibrillation 1,335 European ancestry cases, 12,844 European ancestry controls 1,164 European ancestry cases, 3,607 European ancestry controls Affymetrix, Illumina [~ 2500000] (imputed) 3 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST000602 Genome-wide genotyping array 14179 2015-04-16 25056061 Ripke S 2014-07-22 Nature www.ncbi.nlm.nih.gov/pubmed/25056061 Biological insights from 108 schizophrenia-associated genetic loci. Schizophrenia 32,405 European ancestry cases, 42,221 European ancestry controls, 1,235 European ancestry cases and 1,235 European ancestry controls from 1235 parent-offspring trios, 1,836 East Asian ancestry cases, 3,383 East Asian ancestry controls 1,513 European ancestry cases, 66,236 European ancestry controls Affymetrix, Illumina [9005918] (imputed) 98 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST002539 Genome-wide genotyping array 83550 2014-10-17 24493630 Ahsan H 2014-02-03 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/24493630 A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age. Breast cancer (early onset) 3,523 European ancestry young female cases, 2,702 European ancestry young female controls 3,470 European ancestry young female cases, 5,475 European ancestry young female controls Illumina [1265548] (imputed) 18 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST002346 Genome-wide genotyping array 6225 2016-02-05 25897833 Thompson AG 2015-04-21 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/25897833 Genome-wide association study of behavioural and psychiatric features in human prion disease. Psychotic symptoms and prion disease Up to 170 cases, 5,200 controls NA Illumina [518938] 1 prion disease, psychotic symptoms http://www.ebi.ac.uk/efo/EFO_0004720, http://www.ebi.ac.uk/efo/EFO_0005940 GCST002871 Genome-wide genotyping array 5370 2016-02-05 25897833 Thompson AG 2015-04-21 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/25897833 Genome-wide association study of behavioural and psychiatric features in human prion disease. Mood disorder and prion disease Up to 170 cases, 5,200 controls NA Illumina [518938] 3 prion disease, mood disorder http://www.ebi.ac.uk/efo/EFO_0004720, http://www.ebi.ac.uk/efo/EFO_0004247 GCST002862 Genome-wide genotyping array 5370 2016-02-05 25897833 Thompson AG 2015-04-21 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/25897833 Genome-wide association study of behavioural and psychiatric features in human prion disease. Behavioral disturbance or psychiatric symptoms and prion disease Up to 170 cases, 5,200 controls NA Illumina [518938] 3 prion disease, Behavioral abnormality http://www.ebi.ac.uk/efo/EFO_0004720, http://purl.obolibrary.org/obo/HP_0000708 GCST002866 Genome-wide genotyping array 5370 2016-02-05 25897833 Thompson AG 2015-04-21 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/25897833 Genome-wide association study of behavioural and psychiatric features in human prion disease. Psychotic symptoms in prion disease Up to 170 cases NA Illumina [518938] 3 psychotic symptoms http://www.ebi.ac.uk/efo/EFO_0005940 GCST002867 Genome-wide genotyping array 170 2016-02-05 25897833 Thompson AG 2015-04-21 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/25897833 Genome-wide association study of behavioural and psychiatric features in human prion disease. Mood disorder in prion disease Up to 170 cases NA Illumina [518938] 3 mood disorder http://www.ebi.ac.uk/efo/EFO_0004247 GCST002864 Genome-wide genotyping array 170 2016-02-05 25897833 Thompson AG 2015-04-21 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/25897833 Genome-wide association study of behavioural and psychiatric features in human prion disease. Behavioral disturbance or psychiatric symptoms in prion disease Up to 170 cases NA Illumina [518938] 2 Behavioral abnormality http://purl.obolibrary.org/obo/HP_0000708 GCST002863 Genome-wide genotyping array 170 2016-02-04 25936594 Tomer Y 2015-04-27 J Autoimmun www.ncbi.nlm.nih.gov/pubmed/25936594 Genome wide identification of new genes and pathways in patients with both autoimmune thyroiditis and type 1 diabetes. Type 1 diabetes and autoimmune thyroid diseases 346 European ancestry cases, 727 European ancestry controls 185 European ancestry cases, 340 European ancestry controls Illumina [514008] 11 autoimmune thyroid disease, type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0006812, http://www.ebi.ac.uk/efo/EFO_0001359 GCST002876 Genome-wide genotyping array 1073 2016-02-12 25939698 Tsoi LC 2015-05-05 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25939698 Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci. Psoriasis 3,994 European ancestry cases, 7,699 European ancestry controls 6,268 European ancestry cases, 14,172 European ancestry controls, 5,033 cases, 5,707 controls Illumina [696365] (imputed) 6 psoriasis http://www.ebi.ac.uk/efo/EFO_0000676 GCST002889 Genome-wide genotyping array 11693 2016-01-16 25839716 Ng E 2015-04-02 Environ Res www.ncbi.nlm.nih.gov/pubmed/25839716 Genome-wide association study of plasma levels of polychlorinated biphenyls disclose an association with the CYP2B6 gene in a population-based sample. Polychlorinated biphenyl levels 922 European ancestry individuals NA Illumina [8736858] (imputed) 57 polychlorinated biphenyls measurement http://www.ebi.ac.uk/efo/EFO_0007042 GCST002839 Genome-wide genotyping array 922 2016-01-22 25820613 Warrington NM 2015-03-27 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/25820613 Genome-wide association study of blood lead shows multiple associations near ALAD. Lead levels in blood 5,433 individuals NA Illumina [6391392] (imputed) 15 blood lead measurement http://www.ebi.ac.uk/efo/EFO_0007040 GCST002831 Genome-wide genotyping array 5433 2015-11-14 25637581 Derringer J 2015-01-31 Behav Genet www.ncbi.nlm.nih.gov/pubmed/25637581 Genome-Wide Association Study of Behavioral Disinhibition in a Selected Adolescent Sample. Behavioral disinhibition 1,129 European ancestry individuals, 477 Hispanic individuals, 114 Black individuals, 42 Native American ancestry individuals, 40 Asian or Pacific Islander ancestry individuals, 99 individuals 3,378 European ancestry individuals Affymetrix [696388] 0 behavioural disinhibition measurement http://www.ebi.ac.uk/efo/EFO_0006946 GCST002768 Genome-wide genotyping array 1901 2015-09-22 25648963 Debette S 2014-11-25 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/25648963 Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. Verbal declarative memory Up to 27,337 European ancestry individuals, up to 472 Korkulan individuals, up to 1,267 Erasmus Rucphen Family individuals Up to 10,617 European ancestry individuals, up to 3,811 African American individuals Affymetrix, Illumina [NR] (imputed) 43 memory performance http://www.ebi.ac.uk/efo/EFO_0004874 GCST002701 Genome-wide genotyping array 29076 2015-12-18 25649181 Noordam R 2015-01-20 J Psychiatr Res www.ncbi.nlm.nih.gov/pubmed/25649181 Identifying genetic loci associated with antidepressant drug response with drug-gene interaction models in a population-based study. Depressive symptoms (SSRI exposure interaction) 175 users, 6,268 nonusers NA Illumina [NR] (imputed) 10 drug use measurement, depressive symptom measurement, SSRI use measurement http://www.ebi.ac.uk/efo/EFO_0007010, http://www.ebi.ac.uk/efo/EFO_0007006, http://www.ebi.ac.uk/efo/EFO_0007011 GCST002755 Genome-wide genotyping array 6443 2015-11-17 25631615 Springelkamp H 2015-01-28 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/25631615 Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology. Optic disc area 15,117 European ancestry individuals, 2,131 Erasmus Rucphen Family individuals 2,405 Chinese ancestry individuals, 2,305 Malay ancestry individuals, 2,131 Indian ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 10 optic disc area measurement http://www.ebi.ac.uk/efo/EFO_0006937 GCST002765 Genome-wide genotyping array 17248 2015-11-17 25631615 Springelkamp H 2015-01-28 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/25631615 Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology. Optic cup area 15,087 European ancestry individuals, 2,131 Erasmus Rucphen Family individuals, 2,363 Chinese ancestry individuals, 2,225 Malay ancestry individuals, 2,025 Indian ancestry individuals NA Affymetrix, Illumina [2500000] (imputed) 16 optic cup area measurement http://www.ebi.ac.uk/efo/EFO_0006940 GCST002764 Genome-wide genotyping array 23831 2015-11-17 25631615 Springelkamp H 2015-01-28 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/25631615 Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology. Optic cup area 15,087 European ancestry individuals, 2,131 Erasmus Rucphen Family individuals 2,363 Chinese ancestry individuals, 2,225 Malay ancestry individuals, 2,025 Indian ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 30 optic cup area measurement http://www.ebi.ac.uk/efo/EFO_0006940 GCST002762 Genome-wide genotyping array 17218 2015-11-17 25631615 Springelkamp H 2015-01-28 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/25631615 Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology. Optic disc area 15,117 European ancestry individuals, 2,131 Erasmus Rucphen Family individuals, 2,405 Chinese ancestry individuals, 2,305 Malay ancestry individuals, 2,131 Indian ancestry individuals NA Affymetrix, Illumina [2500000] (imputed) 19 optic disc area measurement http://www.ebi.ac.uk/efo/EFO_0006937 GCST002763 Genome-wide genotyping array 24089 2016-01-14 25643325 Renton AE 2015-04-01 JAMA Neurol www.ncbi.nlm.nih.gov/pubmed/25643325 A genome-wide association study of myasthenia gravis. Myasthenia gravis 972 European ancestry cases, 1,977 European ancestry controls 423 European ancestry cases, 467 European ancestry controls Illumina [8114394] (imputed) 3 Myasthenia gravis http://www.ebi.ac.uk/efo/EFO_0004991 GCST002838 Genome-wide genotyping array 2949 2016-02-10 25898001 Dong C 2015-04-16 Atherosclerosis www.ncbi.nlm.nih.gov/pubmed/25898001 Genetic variants in LEKR1 and GALNT10 modulate sex-difference in carotid intima-media thickness: a genome-wide interaction study. Carotid artery intima media thickness (sex interaction) 931 Hispanic individuals 153 European ancestry individuals, 257 Black individuals Affymetrix [731037] 4 sex interaction measurement, carotid artery intima media thickness http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0007117 GCST002856 Genome-wide genotyping array 931 2016-02-07 25918132 Yucesoy B 2015-04-26 Toxicol Sci www.ncbi.nlm.nih.gov/pubmed/25918132 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma. Diisocyanate-induced asthma 74 European ancestry cases, 824 European ancestry controls NA Illumina [1556551] 180 response to diisocyanate, asthma http://www.ebi.ac.uk/efo/EFO_0006995, http://www.ebi.ac.uk/efo/EFO_0000270 GCST002875 Genome-wide genotyping array 898 2016-02-12 25939597 Berndt SI 2015-05-05 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25939597 Two susceptibility loci identified for prostate cancer aggressiveness. Prostate cancer 4,600 European ancestry cases, 2,941 European ancestry controls 7,779 European ancestry cases, 7,623 European ancestry controls Illumina [1531807] (imputed) 18 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST002890 Genome-wide genotyping array 7541 2016-02-13 25939597 Berndt SI 2015-05-05 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25939597 Two susceptibility loci identified for prostate cancer aggressiveness. Prostate cancer aggressiveness 4,545 European ancestry cases 7,973 European ancestry cases Illumina [1531807] (imputed) 3 cancer aggressiveness measurement, Gleason score measurement, prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0006999, http://www.ebi.ac.uk/efo/EFO_0007000, http://www.ebi.ac.uk/efo/EFO_0001663 GCST002886 Genome-wide genotyping array 4545 2012-12-21 23022100 Franceschini N 2012-09-26 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/23022100 Discovery and fine mapping of serum protein loci through transethnic meta-analysis. Serum total protein level Up to 25,539 European ancestry individuals, 10,168 Japanese ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 12 total blood protein measurement http://www.ebi.ac.uk/efo/EFO_0004536 GCST001698 Genome-wide genotyping array 35707 2012-12-21 23022100 Franceschini N 2012-09-26 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/23022100 Discovery and fine mapping of serum protein loci through transethnic meta-analysis. Serum albumin levels Up to 53,190 European ancestry individuals, 9,380 Japanese ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 16 serum albumin measurement http://www.ebi.ac.uk/efo/EFO_0004535 GCST001699 Genome-wide genotyping array 62570 2013-01-16 23064961 Shaffer JR 2012-10-11 J Dent Res www.ncbi.nlm.nih.gov/pubmed/23064961 GWAS of dental caries patterns in the permanent dentition. Dental caries 920 European ancestry individuals NA Illumina [518997] 32 dental caries http://www.ebi.ac.uk/efo/EFO_0003819 GCST001713 Genome-wide genotyping array 920 2015-02-06 24920014 Cozen W 2014-06-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/24920014 A meta-analysis of Hodgkin lymphoma reveals 19p13.3 TCF3 as a novel susceptibility locus. Hodgkin's lymphoma 1,816 European ancestry cases, 7,877 European ancestry controls 1,281 European ancestry cases, 3,218 European ancestry controls Affymetrix, Illumina [1004829] (imputed) 7 Hodgkins lymphoma http://www.ebi.ac.uk/efo/EFO_0000183 GCST002480 Genome-wide genotyping array 9693 2012-12-11 23023329 Xu J 2012-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23023329 Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4. Prostate cancer 1,417 Han Chinese ancestry cases, 1,008 Han Chinese ancestry controls 3,067 Han Chinese ancestry cases, 7,926 Han Chinese ancestry controls Illumina [587294] 3 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST001702 Genome-wide genotyping array 2425 2015-01-21 24974787 Meng W 2014-06-26 Eur J Pain www.ncbi.nlm.nih.gov/pubmed/24974787 A genome-wide association study suggests an association of Chr8p21.3 (GFRA2) with diabetic neuropathic pain. Neuropathic pain in type 2 diabetes 572 European ancestry cases, 2,491 European ancestry controls NA Affymetrix, Illumina [6494962] (imputed) 2 neuropathic pain http://www.ebi.ac.uk/efo/EFO_0005762 GCST002507 Genome-wide genotyping array 3063 2015-11-21 25710658 Diouf B 2015-02-24 JAMA www.ncbi.nlm.nih.gov/pubmed/25710658 Association of an inherited genetic variant with vincristine-related peripheral neuropathy in children with acute lymphoblastic leukemia. Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia 53 European ancestry cases with peripheral neuropathy, 156 cases without peripheral neuropathy, 10 African ancestry cases with peripheral neuropathy, 33 African ancestry cases without peripheral neuropathy, 1 Asian ancestry case with peripheral neuropathy, 1 Asian ancestry case without peripheral neuropathy, 14 Hispanic cases with peripheral neuropathy, 30 Hispanic cases without peripheral neuropathy, 8 cases with peripheral neuropathy, 15 cases without peripheral neuropathy NA Affymetrix [1576016] (imputed) 5 peripheral neuropathy, response to vincristine http://www.ebi.ac.uk/efo/EFO_0003100, http://www.ebi.ac.uk/efo/EFO_0006950 GCST002792 Genome-wide genotyping array 321 2015-12-16 25672763 Ueta M 2015-02-08 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/25672763 IKZF1, a new susceptibility gene for cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis with severe mucosal involvement. Cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) with severe mucosal involvement 117 Japanese ancestry cases, 691 Japanese ancestry controls 43 East Asian ancestry cases, 278 East Asian ancestry controls, 20 Indian ancestry cases, 56 Indian ancestry controls, 39 Brazilian ancestry cases, 135 Brazilian ancestry controls Affymetrix [449205] 1 Stevens-Johnson syndrome, toxic epidermal necrolysis, response to cold medicine http://www.ebi.ac.uk/efo/EFO_0004276, http://www.ebi.ac.uk/efo/EFO_0004775, http://www.ebi.ac.uk/efo/EFO_0006997 GCST002779 Genome-wide genotyping array 808 2016-01-05 25628645 Tong Y 2015-01-13 Front Genet www.ncbi.nlm.nih.gov/pubmed/25628645 Identification of genetic variants or genes that are associated with Homoharringtonine (HHT) response through a genome-wide association study in human lymphoblastoid cell lines (LCLs). Response to Homoharringtonine (cytotoxicity) 93 African American ancestry lymphoblastoid cell lines, 91 European ancestry lymphoblastoid cell lines, 94 Han Chinese ancestry lymphoblastoid cell lines NA Affymetrix, Illumina [6750581] (imputed) 10 response to homoharringtonine, cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0006996, http://www.ebi.ac.uk/efo/EFO_0006952 GCST002749 Genome-wide genotyping array 278 2016-02-11 25935875 Varenhorst C 2015-05-02 Eur Heart J www.ncbi.nlm.nih.gov/pubmed/25935875 Effect of genetic variations on ticagrelor plasma levels and clinical outcomes. Ticagrelor levels in individuals with acute coronary syndromes treated with ticagrelor 1,794 European ancestry cases, 18 African and Asian ancestry cases 1,922 European ancestry cases, 19 African and Asian ancestry cases Illumina [10962468] (imputed) 6 ticagrelor measurement http://www.ebi.ac.uk/efo/EFO_0007007 GCST002882 Genome-wide genotyping array 1812 2016-02-11 25935875 Varenhorst C 2015-05-02 Eur Heart J www.ncbi.nlm.nih.gov/pubmed/25935875 Effect of genetic variations on ticagrelor plasma levels and clinical outcomes. AR-C124910XX levels in individuals with acute coronary syndromes treated with ticagrelor 1,794 European ancestry cases, 18 African and Asian ancestry cases 1,922 European ancestry cases, 19 African and Asian ancestry cases Illumina [10962468] (imputed) 2 AR-C124910XX measurement http://www.ebi.ac.uk/efo/EFO_0007020 GCST002883 Genome-wide genotyping array 1812 2015-09-10 25917933 Zai CC 2014-11-20 J Psychiatr Res www.ncbi.nlm.nih.gov/pubmed/25917933 A genome-wide association study of suicide severity scores in bipolar disorder. Suicide in bipolar disorder 959 European ancestry individuals NA Affymetrix, Illumina [2659407] (imputed) 4 suicide behaviour measurement, attempted suicide http://www.ebi.ac.uk/efo/EFO_0006882, http://www.ebi.ac.uk/efo/EFO_0004321 GCST002699 Genome-wide genotyping array 959 2013-01-31 23151678 Takata R 2012-11-15 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/23151678 Impact of four loci on serum tamsulosin hydrochloride concentration. Serum tamsulosin hydrochloride concentration 182 Japanese ancestry individuals NA Illumina [481678] 4 response to tamsulosin http://purl.obolibrary.org/obo/GO_1901905 GCST001744 Genome-wide genotyping array 182 2015-06-14 25352340 Benyamin B 2014-10-29 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25352340 Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Iron status biomarkers (ferritin levels) 23,986 European ancestry individuals Up to 24,986 European ancestry individuals Affymetrix, Illumina [~ 2100000] (imputed) 5 iron biomarker measurement, ferritin measurement http://www.ebi.ac.uk/efo/EFO_0004461, http://www.ebi.ac.uk/efo/EFO_0004459 GCST002677 Genome-wide genotyping array 23986 2015-06-14 25352340 Benyamin B 2014-10-29 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25352340 Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Iron status biomarkers (transferrin saturation) 23,986 European ancestry individuals Up to 24,986 European ancestry individuals Affymetrix, Illumina [~ 2100000] (imputed) 6 iron biomarker measurement, transferrin saturation measurement http://www.ebi.ac.uk/efo/EFO_0004461, http://www.ebi.ac.uk/efo/EFO_0006333 GCST002680 Genome-wide genotyping array 23986 2015-06-14 25352340 Benyamin B 2014-10-29 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25352340 Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Iron status biomarkers (iron levels) 23,986 European ancestry individuals Up to 24,986 European ancestry individuals Affymetrix, Illumina [~ 2100000] (imputed) 5 iron biomarker measurement, serum iron measurement http://www.ebi.ac.uk/efo/EFO_0004461, http://www.ebi.ac.uk/efo/EFO_0006332 GCST002679 Genome-wide genotyping array 23986 2015-06-14 25352340 Benyamin B 2014-10-29 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25352340 Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Iron status biomarkers (transferrin levels) 23,986 European ancestry individuals Up to 24,986 European ancestry individuals Affymetrix, Illumina [~ 2100000] (imputed) 9 iron biomarker measurement, transferrin measurement http://www.ebi.ac.uk/efo/EFO_0004461, http://www.ebi.ac.uk/efo/EFO_0006341 GCST002678 Genome-wide genotyping array 23986 2015-06-26 25261932 Cerhan JR 2014-09-28 Nat Genet www.ncbi.nlm.nih.gov/pubmed/25261932 Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma. Diffuse large B cell lymphoma 3,857 European ancestry cases, 7,666 European ancestry controls 1,359 European ancestry cases, 4,557 European ancestry controls Illumina [8363971] (imputed) 8 diffuse large B-cell lymphoma http://www.ebi.ac.uk/efo/EFO_0000403 GCST002636 Genome-wide genotyping array 11523 2015-06-27 25271088 Singh A 2014-10-01 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/25271088 Gene by stress genome-wide interaction analysis and path analysis identify EBF1 as a cardiovascular and metabolic risk gene. Hip circumference (psychosocial stress interaction) 2,460 European ancestry individuals, 548 Chinese ancestry individuals, 1,547 African American individuals, 1,250 Hispanic individuals 3,157 European ancestry individuals Affymetrix [528298] 5 hip circumference, psychosocial stress measurement http://www.ebi.ac.uk/efo/EFO_0005093, http://www.ebi.ac.uk/efo/EFO_0006783 GCST002641 Genome-wide genotyping array 5805 2013-05-11 23400010 Del-Aguila JL 2013-02-12 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/23400010 Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans. Thiazide-induced adverse metabolic effects in hypertensive patients 425 European ancestry cases, 342 African American cases NA Affymetrix, Illumina [> 2000000] (imputed) 59 response to hydrochlorothiazide, triglyceride measurement, fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0005202, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0004465 GCST001859 Genome-wide genotyping array 767 2015-11-17 25656473 de With SA 2015-02-05 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/25656473 Genome-wide association study of lymphoblast cell viability after clozapine exposure. Clozapine-induced cytotoxicity 90 European ancestry lymphoblast cell lines NA NR [2092490] 18 cytotoxicity measurement, response to clozapine http://www.ebi.ac.uk/efo/EFO_0006952, http://purl.obolibrary.org/obo/GO_0097338 GCST002777 Genome-wide genotyping array 90 2016-02-10 25865494 Chan Y 2015-04-09 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/25865494 Genome-wide Analysis of Body Proportion Classifies Height-Associated Variants by Mechanism of Action and Implicates Genes Important for Skeletal Development. Sitting height ratio 3,545 African American individuals, 12,965 European ancestry women, 8,625 European ancestry men NA Affymetrix, Illumina [up to 10250422] (imputed) 44 sitting height ratio http://www.ebi.ac.uk/efo/EFO_0007118 GCST002843 Genome-wide genotyping array 25135 2015-11-20 25886283 Chang X 2015-04-17 PLoS One www.ncbi.nlm.nih.gov/pubmed/25886283 Genome-wide association study of serum minerals levels in children of different ethnic background. Magnesium levels 2,317 European ancestry children, 1,283 African American ancestry children NA Illumina [up to 509150] 15 magnesium measurement http://www.ebi.ac.uk/efo/EFO_0004845 GCST002860 Genome-wide genotyping array 3600 2015-11-20 25886283 Chang X 2015-04-17 PLoS One www.ncbi.nlm.nih.gov/pubmed/25886283 Genome-wide association study of serum minerals levels in children of different ethnic background. Calcium levels 5,261 European ancestry children, 3,817 African American ancestry children NA Illumina [up to 507950] 6 calcium measurement http://www.ebi.ac.uk/efo/EFO_0004838 GCST002857 Genome-wide genotyping array 9078 2015-08-01 25533513 Yao SL 2014-12-22 Chin J Integr Med www.ncbi.nlm.nih.gov/pubmed/25533513 Genome-wide association study on susceptibility genes associated with yang-deficiency constitution: A small sample case-control study. Yang-deficiency constitution 30 cases, 30 balanced constitution controls NA Affymetrix [668548] 1 yang deficiency http://www.ebi.ac.uk/efo/EFO_0006817 GCST002728 Genome-wide genotyping array 60 2015-12-02 25897834 Biernacka JM 2015-04-21 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/25897834 The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response. Response to serotonin reuptake inhibitors in major depressive disorder 298 European ancestry cases, 567 Asian ancestry cases, 1529 European and other ancestry cases NA Illumina [~ 7000000] (imputed) 20 response to selective serotonin reuptake inhibitor http://www.ebi.ac.uk/efo/EFO_0005658 GCST002868 Genome-wide genotyping array 2394 2016-02-04 25918841 Sanchez-Juan P 2015-04-28 PLoS One www.ncbi.nlm.nih.gov/pubmed/25918841 A genome wide association study links glutamate receptor pathway to sporadic Creutzfeldt-Jakob disease risk. Creutzfeldt-Jakob disease (sporadic) 434 European ancestry cases, 1,939 European ancestry controls 1,109 European ancestry cases, 2,264 European ancestry controls Affymetrix [279389] 2 sporadic Creutzfeld Jacob disease http://www.ebi.ac.uk/efo/EFO_1000656 GCST002878 Genome-wide genotyping array 2373 2016-02-10 25903422 Yin X 2015-04-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25903422 Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. Psoriasis 3,496 European ancestry cases, 5,186 European ancestry controls, 1,588 Chinese ancestry cases, 3,546 Chinese ancestry controls 5,134 European ancestry cases, 5,633 European ancestry controls, 5,151 Chinese ancestry cases, 5,152 Chinese ancestry controls Illumina [up to 4778154] (imputed) 68 psoriasis http://www.ebi.ac.uk/efo/EFO_0000676 GCST002874 Genome-wide genotyping array 13816 2015-05-07 25162662 Liao M 2014-08-27 PLoS One www.ncbi.nlm.nih.gov/pubmed/25162662 Genome-wide association study identifies variants in PMS1 associated with serum ferritin in a Chinese population. Ferritin levels 1,999 Han Chinese ancestry individuals 1,496 Chinese ancestry individuals Illumina [1940243] (imputed) 1 ferritin measurement http://www.ebi.ac.uk/efo/EFO_0004459 GCST002578 Genome-wide genotyping array 1999 2013-01-30 23144326 Kim DK 2012-11-09 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/23144326 Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease. Chronic obstructive pulmonary disease-related biomarkers Up to 1,951 European ancestry smokers NA Illumina [588352] 34 tumor necrosis factor-alpha measurement, interleukin-6 measurement, chronic obstructive pulmonary disease, interleukin-8 measurement, fibrinogen measurement, C-reactive protein measurement, CC16 measurement, surfactant protein D measurement http://www.ebi.ac.uk/efo/EFO_0004684, http://www.ebi.ac.uk/efo/EFO_0004810, http://www.ebi.ac.uk/efo/EFO_0000341, http://www.ebi.ac.uk/efo/EFO_0004811, http://www.ebi.ac.uk/efo/EFO_0004623, http://www.ebi.ac.uk/efo/EFO_0004458, http://www.ebi.ac.uk/efo/EFO_0005080, http://www.ebi.ac.uk/efo/EFO_0005081 GCST001737 Genome-wide genotyping array 1951 2015-04-23 25117820 Schneider BP 2014-08-12 Br J Cancer www.ncbi.nlm.nih.gov/pubmed/25117820 Genetic variant predicts bevacizumab-induced hypertension in ECOG-5103 and ECOG-2100. Response to chemotherapy in breast cancer (hypertension) (bevacizumab) 255 European ancestry cases, 387 European ancestry controls NA Illumina [up to 810372] (imputed) 3 response to bevacizumab, chemotherapy-induced hypertension http://www.ebi.ac.uk/efo/EFO_0005943, http://www.ebi.ac.uk/efo/EFO_0005942 GCST002567 Genome-wide genotyping array 642 2015-04-23 25117820 Schneider BP 2014-08-12 Br J Cancer www.ncbi.nlm.nih.gov/pubmed/25117820 Genetic variant predicts bevacizumab-induced hypertension in ECOG-5103 and ECOG-2100. Response to chemotherapy in breast cancer hypertensive cases (cumulative dose) (bevacizumab) 255 European ancestry cases, 387 European ancestry controls NA Illumina [up to 810372] (imputed) 13 cumulative dose response to bevacizumab http://www.ebi.ac.uk/efo/EFO_0005944 GCST002566 Genome-wide genotyping array 642 2015-06-27 25411281 Dashti HS 2014-10-08 Am J Clin Nutr www.ncbi.nlm.nih.gov/pubmed/25411281 Meta-analysis of genome-wide association studies for circulating phylloquinone concentrations. Circulating phylloquinone levels 2,138 European ancestry individuals NA Affymetrix, Illumina [2543887] (imputed) 5 vitamin K measurement http://www.ebi.ac.uk/efo/EFO_0004618 GCST002653 Genome-wide genotyping array 2138 2011-06-18 21647700 Below JE 2011-06-07 Diabetologia www.ncbi.nlm.nih.gov/pubmed/21647700 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals. Type 2 diabetes 837 Mexican American cases, 436 Mexican American controls 967 Mexican ancestry cases, 343 Mexican ancestry controls Affymetrix [1829586] (imputed) 1 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST001092 Genome-wide genotyping array 1273 2015-06-24 25353672 Fernandez-Navarro P 2014-10-29 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/25353672 Genome wide association study identifies a novel putative mammographic density locus at 1q12-q21. Mammographic density 239 European ancestry low mammographic density females, 239 European ancestry high mammographic density females NA Illumina [575374] 5 mammographic density measurement http://www.ebi.ac.uk/efo/EFO_0005941 GCST002676 Genome-wide genotyping array 478 2015-09-15 25387708 Vaidyanathan U 2014-12-01 Psychophysiology www.ncbi.nlm.nih.gov/pubmed/25387708 Heritability and molecular genetic basis of acoustic startle eye blink and affectively modulated startle response: a genome-wide association study. Acoustic startle blink response 3,323 European ancestry twins and their parents NA Illumina [527829] 6 acoustic startle blink response measurement http://www.ebi.ac.uk/efo/EFO_0006875 GCST002708 Genome-wide genotyping array 3323 2015-08-13 25705158 Shim U 2014-12-31 Genomics Inform www.ncbi.nlm.nih.gov/pubmed/25705158 Pathway Analysis of Metabolic Syndrome Using a Genome-Wide Association Study of Korea Associated Resource (KARE) Cohorts. Metabolic syndrome 3,253 Korean ancestry cases, 5,589 Korean ancestry controls NA Affymetrix [312121] 2 metabolic syndrome http://www.ebi.ac.uk/efo/EFO_0000195 GCST002732 Genome-wide genotyping array 8842 2015-11-21 25713168 Leng S 2015-02-23 J Natl Cancer Inst www.ncbi.nlm.nih.gov/pubmed/25713168 15q12 variants, sputum gene promoter hypermethylation, and lung cancer risk: a GWAS in smokers. Gene methylation in lung tissue 1,163 European ancestry smoker individuals 718 European ancestry smoker individuals Illumina [1599980] 3 gene methylation measurement http://www.ebi.ac.uk/efo/EFO_0006959 GCST002786 Genome-wide genotyping array 1163 2016-01-13 25710614 Hong X 2015-02-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25710614 Genome-wide association study identifies peanut allergy-specific loci and evidence of epigenetic mediation in US children. Peanut allergy 316 European ancestry child cases, 144 European ancestry non-allergic non-sensitized normal child controls, 589 European ancestry uncertain phenotype child controls, 1,148 European ancestry uncertain phenotype adult controls 62 European ancestry child cases, 69 European ancestry child controls, 24 child cases, 58 child controls Illumina [6459842] (imputed) 3 peanut allergy measurement http://www.ebi.ac.uk/efo/EFO_0007017 GCST002791 Genome-wide genotyping array 2197 2016-01-13 25710614 Hong X 2015-02-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25710614 Genome-wide association study identifies peanut allergy-specific loci and evidence of epigenetic mediation in US children. Milk allergy 291 European ancestry child cases, 144 European ancestry non-allergic non-sensitized normal child controls, 614 European ancestry uncertain phenotype child controls, 1,148 European ancestry uncertain phenotype adult controls NA Illumina [6459842] (imputed) 5 milk allergy measurement http://www.ebi.ac.uk/efo/EFO_0007019 GCST002788 Genome-wide genotyping array 2197 2016-01-13 25710614 Hong X 2015-02-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25710614 Genome-wide association study identifies peanut allergy-specific loci and evidence of epigenetic mediation in US children. Egg allergy 217 European ancestry child cases, 144 European ancestry non-allergic non-sensitized normal child controls, 688 European ancestry uncertain phenotype child controls, 1,148 European ancestry uncertain phenotype adult controls NA Illumina [6459842] (imputed) 5 egg allergy measurement http://www.ebi.ac.uk/efo/EFO_0007018 GCST002789 Genome-wide genotyping array 2197 2016-01-13 25710614 Hong X 2015-02-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25710614 Genome-wide association study identifies peanut allergy-specific loci and evidence of epigenetic mediation in US children. Food allergy 671 European ancestry child cases, 144 European ancestry non-allergic non-sensitized child controls, 234 European ancestry uncertain phenotype child controls, 1,148 European ancestry uncertain phenotype adult controls NA Illumina [6459842] (imputed) 5 food allergy measurement http://www.ebi.ac.uk/efo/EFO_0007016 GCST002790 Genome-wide genotyping array 2197 2015-12-18 25663231 Beecham GW 2015-02-06 Neurology www.ncbi.nlm.nih.gov/pubmed/25663231 PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease. Parkinson disease and lewy body pathology 484 European ancestry cases, 1,145 European ancestry controls NA Illumina [3922209] (imputed) 10 Parkinson's disease, Lewy body measurement http://www.ebi.ac.uk/efo/EFO_0002508, http://www.ebi.ac.uk/efo/EFO_0007021 GCST002778 Genome-wide genotyping array 1629 2015-11-07 25629512 Cheng CY 2015-01-28 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25629512 New loci and coding variants confer risk for age-related macular degeneration in East Asians. Exudative age-related macular degeneration 2,119 East Asian ancestry cases, 5,691 East Asian ancestry controls 4,226 East Asian ancestry cases, 10,289 East Asian ancestry controls Illumina [4471719] (imputed) 7 wet macular degeneration http://www.ebi.ac.uk/efo/EFO_0004683 GCST002766 Genome-wide genotyping array 7810 2016-03-24 26025379 Ng E 2015-05-29 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26025379 Genome-wide association study of toxic metals and trace elements reveals novel associations. Nickel levels 949 European ancestry individuals NA Illumina [8736858] (imputed) 28 blood nickel measurement http://www.ebi.ac.uk/efo/EFO_0007583 GCST002928 Genome-wide genotyping array 949 2016-03-24 26025379 Ng E 2015-05-29 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26025379 Genome-wide association study of toxic metals and trace elements reveals novel associations. Chromium levels 949 European ancestry individuals NA Illumina [8736858] (imputed) 19 blood chromium measurement http://www.ebi.ac.uk/efo/EFO_0007579 GCST002929 Genome-wide genotyping array 949 2016-03-24 26025379 Ng E 2015-05-29 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26025379 Genome-wide association study of toxic metals and trace elements reveals novel associations. Cobalt levels 949 European ancestry individuals NA Illumina [8736858] (imputed) 19 blood cobalt measurement http://www.ebi.ac.uk/efo/EFO_0007577 GCST002930 Genome-wide genotyping array 949 2016-03-24 26025379 Ng E 2015-05-29 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26025379 Genome-wide association study of toxic metals and trace elements reveals novel associations. Aluminium levels 949 European ancestry individuals NA Illumina [8736858] (imputed) 16 blood aluminium measurement http://www.ebi.ac.uk/efo/EFO_0007575 GCST002931 Genome-wide genotyping array 949 2016-03-24 26025379 Ng E 2015-05-29 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26025379 Genome-wide association study of toxic metals and trace elements reveals novel associations. Manganese levels 949 European ancestry individuals NA Illumina [8736858] (imputed) 37 blood manganese measurement http://www.ebi.ac.uk/efo/EFO_0007581 GCST002932 Genome-wide genotyping array 949 2016-03-24 26025379 Ng E 2015-05-29 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26025379 Genome-wide association study of toxic metals and trace elements reveals novel associations. Molybdenum levels 949 European ancestry individuals NA Illumina [8736858] (imputed) 17 blood molybdenum measurement http://www.ebi.ac.uk/efo/EFO_0007582 GCST002937 Genome-wide genotyping array 949 2016-03-24 26025379 Ng E 2015-05-29 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26025379 Genome-wide association study of toxic metals and trace elements reveals novel associations. Lead levels 949 European ancestry individuals NA Illumina [8736858] (imputed) 28 blood lead measurement http://www.ebi.ac.uk/efo/EFO_0007040 GCST002935 Genome-wide genotyping array 949 2016-03-24 26025379 Ng E 2015-05-29 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26025379 Genome-wide association study of toxic metals and trace elements reveals novel associations. Zinc levels 949 European ancestry individuals NA Illumina [8736858] (imputed) 24 blood zinc measurement http://www.ebi.ac.uk/efo/EFO_0007584 GCST002934 Genome-wide genotyping array 949 2016-03-24 26025379 Ng E 2015-05-29 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26025379 Genome-wide association study of toxic metals and trace elements reveals novel associations. Mercury levels 949 European ancestry individuals NA Illumina [8736858] (imputed) 24 blood mercury measurement http://www.ebi.ac.uk/efo/EFO_0007580 GCST002927 Genome-wide genotyping array 949 2016-03-24 26025379 Ng E 2015-05-29 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26025379 Genome-wide association study of toxic metals and trace elements reveals novel associations. Cadmium levels 949 European ancestry individuals NA Illumina [8736858] (imputed) 30 blood cadmium measurement http://www.ebi.ac.uk/efo/EFO_0007576 GCST002936 Genome-wide genotyping array 949 2016-03-24 26025379 Ng E 2015-05-29 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26025379 Genome-wide association study of toxic metals and trace elements reveals novel associations. Copper levels 949 European ancestry individuals NA Illumina [8736858] (imputed) 42 blood copper measurement http://www.ebi.ac.uk/efo/EFO_0007578 GCST002938 Genome-wide genotyping array 949 2016-12-01 26910538 Choi SH 2016-02-24 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/26910538 Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies. Vascular endothelial growth factor levels 9541 European ancestry individuals, 1,115 Cilento (founder/genetic isolated) individuals, 897 Ogliastran (founder/genetic isolated) individuals, 1,759 Val Borbera (founder/genetic isolated) individuals 2,141 European ancestry individuals, 659 Sorbian (founder/genetic isolated) individuals Affymetrix, Illumina [6705861] (imputed) 10 vascular endothelial growth factor measurement http://www.ebi.ac.uk/efo/EFO_0004762 GCST003403 Genome-wide genotyping array 13312 2016-12-01 26879886 Wakil SM 2016-02-16 Clin Genet www.ncbi.nlm.nih.gov/pubmed/26879886 A common variant association study reveals novel susceptibility loci for low HDL-cholesterol levels in ethnic Arabs. Low high density lipoprotein cholesterol levels 1,747 Saudi Arab ancestry cases, 2,335 Saudi Arab ancestry controls 517 Saudi Arab ancestry cases, 896 Saudi Arab ancestry controls Affymetrix [~ 8000000] (imputed) 11 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST003391 Genome-wide genotyping array 4082 2016-03-24 21116278 Furney SJ 2010-11-30 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/21116278 Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. Entorhinal cortical thickness 424 European ancestry mild cognitive impairment cases, 236 European ancestry Alzheimer's disease cases, 279 European ancestry controls NA Illumina [478011] 5 cortical thickness http://www.ebi.ac.uk/efo/EFO_0004840 GCST000894 Genome-wide genotyping array 939 2016-03-24 21116278 Furney SJ 2010-11-30 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/21116278 Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. Entorhinal cortical volume 424 European ancestry mild cognitive impairment cases, 236 European ancestry Alzheimer's disease cases, 279 European ancestry controls NA Illumina [478011] 1 entorhinal cortical volume http://www.ebi.ac.uk/efo/EFO_0005092 GCST000899 Genome-wide genotyping array 939 2016-03-24 21116278 Furney SJ 2010-11-30 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/21116278 Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. Whole-brain volume 434 European ancestry mild cognitive impairment cases, 245 European ancestry Alzheimer's disease cases, 284 European ancestry controls NA Illumina [478011] 4 whole-brain volume http://www.ebi.ac.uk/efo/EFO_0005089 GCST000891 Genome-wide genotyping array 963 2016-03-24 21116278 Furney SJ 2010-11-30 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/21116278 Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. Hippocampal volume 424 European ancestry mild cognitive impairment cases, 236 European ancestry Alzheimer's disease cases, 279 European ancestry controls NA Illumina [478011] 3 hippocampal volume http://www.ebi.ac.uk/efo/EFO_0005035 GCST000890 Genome-wide genotyping array 939 2016-03-24 21116278 Furney SJ 2010-11-30 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/21116278 Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. Entorhinal cortical thickness (Alzheimer's disease interaction) 424 European ancestry mild cognitive impairment cases, 236 European ancestry Alzheimer's disease cases, 279 European ancestry controls NA Illumina [478011] 1 Alzheimer's disease, cortical thickness http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0004840 GCST000889 Genome-wide genotyping array 939 2016-03-24 21116278 Furney SJ 2010-11-30 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/21116278 Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. Total ventricular volume 424 European ancestry mild cognitive impairment cases, 236 European ancestry Alzheimer's disease cases, 279 European ancestry controls NA Illumina [478011] 8 brain volume measurement http://www.ebi.ac.uk/efo/EFO_0006930 GCST000898 Genome-wide genotyping array 939 2016-03-24 21116278 Furney SJ 2010-11-30 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/21116278 Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. Entorhinal cortical volume (Alzheimer's disease interaction) 424 European ancestry mild cognitive impairment cases, 236 European ancestry Alzheimer's disease cases, 279 European ancestry controls NA Illumina [478011] 1 Alzheimer's disease, entorhinal cortical volume http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0005092 GCST000893 Genome-wide genotyping array 939 2016-03-24 21116278 Furney SJ 2010-11-30 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/21116278 Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. Total ventricular volume (Alzheimer's disease interaction) 424 European ancestry mild cognitive impairment cases, 236 European ancestry Alzheimer's disease cases, 279 European ancestry controls NA Illumina [478011] 11 Alzheimer's disease, brain volume measurement http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0006930 GCST000892 Genome-wide genotyping array 939 2016-03-24 21116278 Furney SJ 2010-11-30 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/21116278 Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. Whole-brain volume (Alzheimer's disease interaction) 434 European ancestry mild cognitive impairment cases, 245 European ancestry Alzheimer's disease cases, 284 European ancestry controls NA Illumina [478011] 4 Alzheimer's disease, whole-brain volume http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0005089 GCST000895 Genome-wide genotyping array 963 2016-03-24 21116278 Furney SJ 2010-11-30 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/21116278 Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. Hippocampal volume (Alzheimer's disease interaction) 424 European ancestry mild cognitive impairment cases, 236 European ancestry Alzheimer's disease cases, 279 European ancestry controls NA Illumina [478011] 0 Alzheimer's disease, hippocampal volume http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0005035 GCST000897 Genome-wide genotyping array 939 2016-12-16 26926045 Adhikari K 2016-03-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26926045 A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features. Scalp hair shape 6,357 Latin American individuals NA Illumina [9143600] (imputed) 9 hair shape measurement http://www.ebi.ac.uk/efo/EFO_0007824 GCST003474 Genome-wide genotyping array 6357 2016-12-16 26926045 Adhikari K 2016-03-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26926045 A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features. Beard thickness 2,922 Latin American individuals NA Illumina [9143600] (imputed) 8 facial hair thickness measurement http://www.ebi.ac.uk/efo/EFO_0007823 GCST003475 Genome-wide genotyping array 2922 2016-12-16 26926045 Adhikari K 2016-03-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26926045 A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features. Eyebrow thickness 2,922 Latin American individuals NA Illumina [9143600] (imputed) 10 facial hair thickness measurement http://www.ebi.ac.uk/efo/EFO_0007823 GCST003476 Genome-wide genotyping array 2922 2016-12-16 26926045 Adhikari K 2016-03-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26926045 A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features. Monobrow thickness 2,922 Latin American individuals NA Illumina [9143600] (imputed) 7 facial hair thickness measurement http://www.ebi.ac.uk/efo/EFO_0007823 GCST003477 Genome-wide genotyping array 2922 2016-12-16 26926045 Adhikari K 2016-03-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26926045 A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features. Hair greying 6,357 Latin American individuals NA Illumina [9143600] (imputed) 8 hair colour measurement http://www.ebi.ac.uk/efo/EFO_0007822 GCST003478 Genome-wide genotyping array 6357 2016-12-16 26926045 Adhikari K 2016-03-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26926045 A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features. Hair color 6,357 Latin American individuals NA Illumina [9143600] (imputed) 11 hair colour measurement http://www.ebi.ac.uk/efo/EFO_0007822 GCST003479 Genome-wide genotyping array 6357 2016-12-16 26926045 Adhikari K 2016-03-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26926045 A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features. Balding 6,357 Latin American individuals NA Illumina [9143600] (imputed) 2 balding measurement http://www.ebi.ac.uk/efo/EFO_0007825 GCST003480 Genome-wide genotyping array 6357 2016-10-05 26704534 Sapkota BR 2015-12-15 J Steroid Biochem Mol Biol www.ncbi.nlm.nih.gov/pubmed/26704534 Genome-wide association study of 25(OH) Vitamin D concentrations in Punjabi Sikhs: Results of the Asian Indian diabetic heart study. Vitamin D levels 1,387 Punjabi Sikh ancestry individuals 2,151 Punjabi Sikh ancestry individuals Illumina [5904251] (imputed) 2 vitamin D measurement http://www.ebi.ac.uk/efo/EFO_0004631 GCST003191 Genome-wide genotyping array 1387 2016-01-27 25673413 Locke AE 2015-02-12 Nature www.ncbi.nlm.nih.gov/pubmed/25673413 Genetic studies of body mass index yield new insights for obesity biology. Body mass index up to 104,666 European ancestry male individuals, up to 132,115 European ancestry female individuals, 370 African American male individuals, 517 African American female individuals, 512 Hispanic male individuals, 764 Hispanic female individuals up to 48,274 European ancestry male individuals, up to 39,864 European ancestry female individuals, 2,441 African American or Afro-Caribbean male individuals, 6,314 African American or Afro-Caribbean female individuals, 919 Filipino male individuals, 828 Filipino female individuals, 205 Seychellois male individuals, 287 Seychellois female individuals, 2,964 South Asian ancestry male individuals, 658 South Asian ancestry female individuals Affymetrix, Illumina [2550021] 634 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST002783 Genome-wide genotyping array 238944 2016-12-13 26876947 Saito T 2016-02-11 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/26876947 Pharmacogenomic Study of Clozapine-Induced Agranulocytosis/Granulocytopenia in a Japanese Population. Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia 50 Japanese ancestry cases, 2905 Japanese ancestry controls NA Illumina [522694] 2 Drug-induced agranulocytosis, response to clozapine http://purl.obolibrary.org/obo/HP_0012235, http://purl.obolibrary.org/obo/GO_0097338 GCST003450 Genome-wide genotyping array 2955 2016-12-07 26908436 Siiskonen SJ 2016-02-12 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/26908436 A Genome-Wide Association Study of Cutaneous Squamous Cell Carcinoma among European Descendants. Squamous cell carcinoma 745 European ancestry cases, 12,805 European ancestry controls 531 European ancestry cases, 551 European ancestry controls Affymetrix [2392512] (imputed) 5 squamous cell carcinoma http://www.ebi.ac.uk/efo/EFO_0000707 GCST003422 Genome-wide genotyping array 13550 2016-10-14 26708676 Pulit SL 2015-12-18 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/26708676 Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study. Ischemic stroke (large artery atherosclerosis) up to 2,349 European ancestry cases, up to 220 African ancestry cases, up to 146 Hispanic cases, 26,690 European ancestry controls, 3,354 African ancestry controls, 2,429 Hispanic controls 33 African ancestry cases, 34 East Asian ancestry cases, 1,787 European ancestry cases, 40 Hispanic ancestry cases, 355 South Asian ancestry cases, 239 African ancestry controls, 329 East Asian ancestry controls, 176,782 European ancestry controls, 686 Hispanic controls, 5,193 South Asian ancestry controls Illumina [up to 15400000] (imputed) 2 Ischemic stroke, large artery stroke http://purl.obolibrary.org/obo/HP_0002140, http://www.ebi.ac.uk/efo/EFO_0005524 GCST003259 Genome-wide genotyping array 35188 2016-10-14 26708676 Pulit SL 2015-12-18 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/26708676 Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study. Ischemic stroke (small artery occlusion) up to 2,252 European ancestry cases, up to 381 African ancestry cases, up to 552 Hispanic cases, 26,690 European ancestry controls, 3,354 African ancestry controls, 2,429 Hispanic controls 47 African ancestry cases, 133 East Asian ancestry cases, 1,847 European ancestry cases, 85 Hispanic cases, 314 South Asian ancestry cases, 239 African ancestry controls, 329 East Asian ancestry controls, 217,755 European ancestry controls, 686 Hispanic controls, 5,193 South Asian ancestry stroke controls Illumina [up to 15400000] (imputed) 1 Ischemic stroke, small artery occlusion http://purl.obolibrary.org/obo/HP_0002140, http://www.ebi.ac.uk/efo/EFO_1001495 GCST003260 Genome-wide genotyping array 35658 2016-10-14 26708676 Pulit SL 2015-12-18 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/26708676 Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study. Ischemic stroke (undetermined subtype) up to 8,062 European ancestry cases, up to 1,086 African ancestry cases, up to 362 Hispanic cases, 26,690 European ancestry controls, 3,354 African ancestry controls, 2,429 Hispanic controls 17 African ancestry cases, 17 East Asian ancestry cases, 3,514 European ancestry cases, 149 Hispanic cases, 239 African ancestry controls, 329 East Asian ancestry controls, 259,291 European ancestry controls, 686 Hispanic controls Illumina [up to 15400000] (imputed) 1 Ischemic stroke http://purl.obolibrary.org/obo/HP_0002140 GCST003261 Genome-wide genotyping array 41983 2016-10-14 26708676 Pulit SL 2015-12-18 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/26708676 Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study. Ischemic stroke 14,300 European ancestry cases, 1,609 African ancestry cases, 942 Hispanic cases, 26,690 European ancestry controls, 3,354 African ancestry controls, 2,429 Hispanic controls 996 African ancestry cases, 219 East Asian ancestry cases, 17,334 European ancestry cases, 548 Hispanic cases, 2,385 South Asian ancestry cases, 5,811 African ancestry controls, 329 East Asian ancestry controls, 350,928 European ancestry controls, 686 Hispanic controls, 5,193 South Asian ancestry controls Illumina [up to 15400000] (imputed) 3 Ischemic stroke http://purl.obolibrary.org/obo/HP_0002140 GCST003258 Genome-wide genotyping array 49324 2016-10-14 26708676 Pulit SL 2015-12-18 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/26708676 Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study. Ischemic stroke (cardioembolic) up to 3,400 European ancestry cases, up to 208 African ancestry cases, up to 118 Hispanic cases, 26,690 European ancestry controls, 3,354 African ancestry controls, 2,429 Hispanic controls 98 African ancestry cases, 31 East Asian ancestry cases, 3,436 European ancestry cases, 97 Hispanic cases, 422 South Asian ancestry cases, 2,917 African ancestry controls, 329 East Asian ancestry controls, 274,063 European ancestry controls, 686 Hispanic controls, 5,193 South Asian ancestry controls Illumina [up to 15400000] (imputed) 2 Ischemic stroke, cardiac embolism http://purl.obolibrary.org/obo/HP_0002140, http://www.ebi.ac.uk/efo/EFO_1001493 GCST003257 Genome-wide genotyping array 36199 2016-10-06 26675016 Cha S 2015-12-16 PLoS One www.ncbi.nlm.nih.gov/pubmed/26675016 A Genome-Wide Association Study Uncovers a Genetic Locus Associated with Thoracic-to-Hip Ratio in Koreans. Thoracic-to-hip circumference ratio 2,388 Korean ancestry males, 2,600 Korean ancestry females 767 Korean ancestry males, 1,485 Korean ancestry females Affymetrix [310746] 2 thoracic-to-hip circumference ratio measurement http://www.ebi.ac.uk/efo/EFO_0007769 GCST003197 Genome-wide genotyping array 4988 2016-10-13 26674333 Traylor M 2015-12-16 Neurology www.ncbi.nlm.nih.gov/pubmed/26674333 Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke. White matter hyperintensities in ischemic stroke 3,670 European ancestry cases NA Affymetrix, Illumina [7567914] (imputed) 8 white matter hyperintensity measurement http://www.ebi.ac.uk/efo/EFO_0005665 GCST003245 Genome-wide genotyping array 3670 2016-12-15 26956414 Berndt SI 2016-03-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26956414 Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia. Chronic lymphocytic leukemia 3,100 European ancestry cases, 7,667 European ancestry controls 1,958 cases, 5,530 controls Affymetrix, Illumina [~ 8500000] (imputed) 31 chronic lymphocytic leukemia http://www.ebi.ac.uk/efo/EFO_0000095 GCST003468 Genome-wide genotyping array 10767 2016-12-19 26962152 Offenbacher S 2016-03-08 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26962152 Genome-wide association study of biologically informed periodontal complex traits offers novel insights into the genetic basis of periodontal disease. Periodontal disease-related phenotype (Socransky) 394 European American individuals with periodontal health, 389 European American individuals with mild-moderate periodontitis, 192 European American individuals with severe periodontitis NA Affymetrix [2135235] (imputed) 6 periodontal measurement http://www.ebi.ac.uk/efo/EFO_0007780 GCST003484 Genome-wide genotyping array 975 2019-08-16 26962152 Offenbacher S 2016-03-08 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26962152 Genome-wide association study of biologically informed periodontal complex traits offers novel insights into the genetic basis of periodontal disease. Periodontal disease related phenotype (PCT2) 394 European American individuals with periodontal health, 389 European American individuals with mild-moderate periodontitis, 192 European American individuals with severe periodontitis NA Affymetrix [2135235] (imputed) 0 periodontal measurement http://www.ebi.ac.uk/efo/EFO_0007780 GCST008439 Genome-wide genotyping array 975 2019-08-16 26962152 Offenbacher S 2016-03-08 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26962152 Genome-wide association study of biologically informed periodontal complex traits offers novel insights into the genetic basis of periodontal disease. Periodontal disease related phenotype (PCT3) 394 European American individuals with periodontal health, 389 European American individuals with mild-moderate periodontitis, 192 European American individuals with severe periodontitis NA Affymetrix [2135235] (imputed) 2 periodontal measurement http://www.ebi.ac.uk/efo/EFO_0007780 GCST008440 Genome-wide genotyping array 975 2019-08-16 26962152 Offenbacher S 2016-03-08 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26962152 Genome-wide association study of biologically informed periodontal complex traits offers novel insights into the genetic basis of periodontal disease. Periodontal disease related phenotype (PCT4) 394 European American individuals with periodontal health, 389 European American individuals with mild-moderate periodontitis, 192 European American individuals with severe periodontitis NA Affymetrix [2135235] (imputed) 1 periodontal measurement http://www.ebi.ac.uk/efo/EFO_0007780 GCST008441 Genome-wide genotyping array 975 2019-08-16 26962152 Offenbacher S 2016-03-08 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26962152 Genome-wide association study of biologically informed periodontal complex traits offers novel insights into the genetic basis of periodontal disease. Periodontal disease related phenotype (PCT5) 394 European American individuals with periodontal health, 389 European American individuals with mild-moderate periodontitis, 192 European American individuals with severe periodontitis NA Affymetrix [2135235] (imputed) 3 periodontal measurement http://www.ebi.ac.uk/efo/EFO_0007780 GCST008442 Genome-wide genotyping array 975 2019-08-16 26962152 Offenbacher S 2016-03-08 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26962152 Genome-wide association study of biologically informed periodontal complex traits offers novel insights into the genetic basis of periodontal disease. Periodontal disease related phenotype (PCT6) 394 European American individuals with periodontal health, 389 European American individuals with mild-moderate periodontitis, 192 European American individuals with severe periodontitis NA Affymetrix [2135235] (imputed) 0 periodontal measurement http://www.ebi.ac.uk/efo/EFO_0007780 GCST008443 Genome-wide genotyping array 975 2016-12-08 26950853 Dehghan A 2016-03-07 PLoS One www.ncbi.nlm.nih.gov/pubmed/26950853 Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium. Incident coronary heart disease 2406 European ancestry cases, 21,618 European ancestry controls 3059 European ancestry cases, 28,087 European ancestry controls Affymetrix, Illumina [2543842] (imputed) 2 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST003431 Genome-wide genotyping array 24024 2016-12-08 26950853 Dehghan A 2016-03-07 PLoS One www.ncbi.nlm.nih.gov/pubmed/26950853 Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium. Incident myocardial infarction 1,570 European ancestry cases, at least 21,618 European ancestry controls 2,328 European ancestry cases, 546 African American ancestry cases, 7655 African American ancestry controls, up to 35,233 European ancestry controls Affymetrix, Illumina [2543842] (imputed) 4 myocardial infarction http://www.ebi.ac.uk/efo/EFO_0000612 GCST003430 Genome-wide genotyping array 23188 2016-12-08 26859814 den Braber A 2016-02-09 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/26859814 Obsessive-compulsive symptoms in a large population-based twin-family sample are predicted by clinically based polygenic scores and by genome-wide SNPs. Obsessive-compulsive symptoms 6,931 individuals NA Affymetrix, Illumina, Perlegen [31265038] (imputed) 13 obsessive-compulsive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007802 GCST003434 Genome-wide genotyping array 6931 2016-12-08 26861389 D'Adamo CR 2016-02-06 Nutrients www.ncbi.nlm.nih.gov/pubmed/26861389 A Common Variant in the SETD7 Gene Predicts Serum Lycopene Concentrations. Serum lycopene concentrations 441 Old Order Amish individuals from 308 families NA Affymetrix [2302013] (imputed) 5 lycopene measurement http://www.ebi.ac.uk/efo/EFO_0007801 GCST003433 Genome-wide genotyping array 749 2016-06-08 26030696 Cho MH 2015-06-01 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/26030696 A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes. Percentage gas trapping 3,243 European ancestry chronic obstructive pulmonary disease cases, 901 African American chronic obstructive pulmonary disease cases, 3,062 European ancestry controls, 2,132 African American controls NA Illumina [6900000] (imputed) 17 gas trapping measurement http://www.ebi.ac.uk/efo/EFO_0007628 GCST002942 Genome-wide genotyping array 9338 2016-06-08 26030696 Cho MH 2015-06-01 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/26030696 A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes. Airway imaging phenotypes 5,385 European ancestry chronic obstructive pulmonary disease cases, 901 African American chronic obstructive pulmonary disease cases, 3,613 European ancestry controls, 2,132 African American controls NA Illumina [7600000] (imputed) 14 airway imaging measurement http://www.ebi.ac.uk/efo/EFO_0007627 GCST002941 Genome-wide genotyping array 12031 2016-06-08 26030696 Cho MH 2015-06-01 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/26030696 A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes. Emphysema imaging phenotypes 5,385 European ancestry chronic obstructive pulmonary disease cases, 901 African American chronic obstructive pulmonary disease cases, 3,613 European ancestry controls, 2,132 African American controls NA Illumina [7600000] (imputed) 52 emphysema imaging measurement http://www.ebi.ac.uk/efo/EFO_0007626 GCST002945 Genome-wide genotyping array 12031 2016-10-13 26631737 Teumer A 2015-12-02 Diabetes www.ncbi.nlm.nih.gov/pubmed/26631737 Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes. Urinary albumin-to-creatinine ratio in diabetes up to 5,825 European ancestry cases up to 1,962 European ancestry cases Affymetrix, Illumina [2191945] (imputed) 2 urinary albumin to creatinine ratio http://www.ebi.ac.uk/efo/EFO_0007778 GCST003250 Genome-wide genotyping array 5825 2016-10-14 26631737 Teumer A 2015-12-02 Diabetes www.ncbi.nlm.nih.gov/pubmed/26631737 Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes. Urinary albumin-to-creatinine ratio in non-diabetics up to 46,051 European ancestry individuals NA Affymetrix, Illumina [2191945] (imputed) 10 urinary albumin to creatinine ratio http://www.ebi.ac.uk/efo/EFO_0007778 GCST003254 Genome-wide genotyping array 46051 2016-10-14 26631737 Teumer A 2015-12-02 Diabetes www.ncbi.nlm.nih.gov/pubmed/26631737 Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes. Microalbuminuria up to 54,116 European ancestry cases NA Affymetrix, Illumina [2191945] (imputed) 15 Moderate albuminuria http://purl.obolibrary.org/obo/HP_0012594 GCST003253 Genome-wide genotyping array 54116 2016-10-14 26631737 Teumer A 2015-12-02 Diabetes www.ncbi.nlm.nih.gov/pubmed/26631737 Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes. Urinary albumin-to-creatinine ratio up to 54,450 European ancestry individuals NA Affymetrix, Illumina [2191945] (imputed) 12 urinary albumin to creatinine ratio http://www.ebi.ac.uk/efo/EFO_0007778 GCST003255 Genome-wide genotyping array 54450 2016-10-06 26621817 Cheng TH 2015-12-01 Sci Rep www.ncbi.nlm.nih.gov/pubmed/26621817 Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1. Colorectal or endometrial cancer 5,725 European ancestry colorectal carcinoma cases, 2,212 European ancestry endometrial carcinoma cases, 13,396 European ancestry controls NA Illumina [up to 6000000] (imputed) 16 colorectal cancer, endometrial neoplasm http://www.ebi.ac.uk/efo/EFO_0005842, http://www.ebi.ac.uk/efo/EFO_0004230 GCST003209 Genome-wide genotyping array 21333 2016-10-06 26621817 Cheng TH 2015-12-01 Sci Rep www.ncbi.nlm.nih.gov/pubmed/26621817 Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1. Colorectal or endometrial cancer 5,725 European ancestry colorectal carcinoma cases, 2,212 European ancestry endometrial carcinoma cases, 13,396 European ancestry controls 4,330 European ancestry endometrial carcinoma cases, 26,849 European ancestry controls Illumina [up to 6000000] (imputed) 13 colorectal cancer, endometrial neoplasm http://www.ebi.ac.uk/efo/EFO_0005842, http://www.ebi.ac.uk/efo/EFO_0004230 GCST003208 Genome-wide genotyping array 21333 2015-07-28 25188341 Beecham GW 2014-09-04 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/25188341 Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias. Dementia and core Alzheimer's disease neuropathologic changes up to 3,887 cases, up to 1,027 controls NA Affymetrix, Illumina [NR] (imputed) 51 Dementia, Alzheimer's disease neuropathologic change http://purl.obolibrary.org/obo/HP_0000726, http://www.ebi.ac.uk/efo/EFO_0006801 GCST002593 Genome-wide genotyping array 4914 2015-07-28 25188341 Beecham GW 2014-09-04 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/25188341 Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias. Neurofibrillary tangles up to 4,707 individuals NA Affymetrix, Illumina [NR] (imputed) 37 neurofibrillary tangles measurement http://www.ebi.ac.uk/efo/EFO_0006797 GCST002594 Genome-wide genotyping array 4707 2015-07-28 25188341 Beecham GW 2014-09-04 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/25188341 Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias. Neuritic plaque up to 4,232 individuals NA Affymetrix, Illumina [NR] (imputed) 34 neuritic plaque measurement http://www.ebi.ac.uk/efo/EFO_0006798 GCST002592 Genome-wide genotyping array 4232 2015-07-28 25188341 Beecham GW 2014-09-04 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/25188341 Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias. Lewy body disease up to 3,526 individuals NA Affymetrix, Illumina [NR] (imputed) 40 Lewy body dementia, Lewy body dementia measurement http://www.ebi.ac.uk/efo/EFO_0006792, http://www.ebi.ac.uk/efo/EFO_0006799 GCST002591 Genome-wide genotyping array 3526 2015-07-28 25188341 Beecham GW 2014-09-04 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/25188341 Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias. Vascular brain injury up to 2,940 individuals NA Affymetrix, Illumina [NR] (imputed) 21 vascular brain injury measurement, vascular brain injury http://www.ebi.ac.uk/efo/EFO_0006800, http://www.ebi.ac.uk/efo/EFO_0006791 GCST002590 Genome-wide genotyping array 2940 2015-07-28 25188341 Beecham GW 2014-09-04 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/25188341 Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias. Hippocampal sclerosis 310 cases, 2,576 controls NA Affymetrix, Illumina [NR] (imputed) 29 hippocampal sclerosis of aging http://www.ebi.ac.uk/efo/EFO_0005678 GCST002589 Genome-wide genotyping array 2886 2015-07-28 25188341 Beecham GW 2014-09-04 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/25188341 Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias. Cerebral amyloid angiopathy 1,673 cases, 1,134 controls NA Affymetrix, Illumina [NR] (imputed) 7 cerebral amyloid angiopathy http://www.ebi.ac.uk/efo/EFO_0006790 GCST002588 Genome-wide genotyping array 2807 2016-02-13 26058915 Tin A 2015-05-29 BMC Genet www.ncbi.nlm.nih.gov/pubmed/26058915 Genetic loci for serum magnesium among African-Americans and gene-environment interaction at MUC1 and TRPM6 in European-Americans: the Atherosclerosis Risk in Communities (ARIC) study. Magnesium levels 2,737 African American individuals 942 African American individuals Affymetrix [14825944] (imputed) 5 magnesium measurement http://www.ebi.ac.uk/efo/EFO_0004845 GCST002933 Genome-wide genotyping array 2737 2016-04-21 26025128 Park HW 2015-05-27 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/26025128 Genetic risk factors for decreased bone mineral accretion in children with asthma receiving multiple oral corticosteroid bursts. Bone mineral accretion in asthma (oral corticosteroid dose interaction) 489 European ancestry children NA Illumina [NR] 9 bone mineral accretion measurement, response to corticosteroid http://www.ebi.ac.uk/efo/EFO_0007591, http://purl.obolibrary.org/obo/GO_0031960 GCST002926 Genome-wide genotyping array 489 2016-07-15 26034056 Hoffmann TJ 2015-06-01 Cancer Discov www.ncbi.nlm.nih.gov/pubmed/26034056 A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. Prostate cancer 6,406 European ancestry cases, 601 African American cases, 288 East Asian ancestry cases, 488 Latino cases30,866 European ancestry controls, 1,650 African American controls, 2,938 East Asian ancestry controls, 3,141 Latino controls 4,599 European ancestry cases, 2,265 African American cases, 2,940 European ancestry controls, 2,414 African American controls Affymetrix [up to 19977088] (imputed) 57 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST002944 Genome-wide genotyping array 46378 2016-06-10 26211971 Ogura Y 2015-07-23 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/26211971 A Functional SNP in BNC2 Is Associated with Adolescent Idiopathic Scoliosis. Adolescent idiopathic scoliosis 2,109 Japanese ancestry cases, 11,140 Japanese ancestry controls 2,223 East Asian ancestry cases, 4,724 East Asian ancestry controls Illumina [4420789] (imputed) 4 adolescent idiopathic scoliosis http://www.ebi.ac.uk/efo/EFO_0005423 GCST003052 Genome-wide genotyping array 13249 2016-06-17 26174136 Setoh K 2015-07-15 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26174136 Three missense variants of metabolic syndrome-related genes are associated with alpha-1 antitrypsin levels. Serum alpha1-antitrypsin levels 3,294 Japanese ancestry individuals 6,065 Japanese ancestry individuals Illumina [6569727] (imputed) 3 serum alpha-1-antitrypsin measurement http://www.ebi.ac.uk/efo/EFO_0005415 GCST003028 Genome-wide genotyping array 3294 2016-07-18 26184070 Aebi M 2015-07-16 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/26184070 Gene-set and multivariate genome-wide association analysis of oppositional defiant behavior subtypes in attention-deficit/hyperactivity disorder. Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder 750 European ancestry child and adolescent cases NA Perlegen [1871025] (imputed) 10 oppositional defiant disorder measurement http://www.ebi.ac.uk/efo/EFO_0007679 GCST003030 Genome-wide genotyping array 750 2016-06-28 26174813 Alemany S 2015-07-14 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/26174813 New suggestive genetic loci and biological pathways for attention function in adult attention-deficit/hyperactivity disorder. Attention function in attention deficit hyperactive disorder 479 European ancestry adult cases NA Illumina [799713] 25 attention function measurement http://www.ebi.ac.uk/efo/EFO_0007636 GCST003025 Genome-wide genotyping array 479 2016-06-28 26176695 Warrier V 2015-07-15 PLoS One www.ncbi.nlm.nih.gov/pubmed/26176695 A Pooled Genome-Wide Association Study of Asperger Syndrome. Asperger syndrome 294 European ancestry cases, 318 European ancestry controls NA Affymetrix [NR] 0 Asperger syndrome http://www.ebi.ac.uk/efo/EFO_0003757 GCST003029 Genome-wide genotyping array 612 2016-05-31 26174610 Kwak TJ 2015-07-14 Exp Dermatol www.ncbi.nlm.nih.gov/pubmed/26174610 Identification of a possible susceptibility locus for UVB-induced skin tanning phenotype in Korean females using genomewide association study. Ultraviolet-induced skin pigmentation (minimal erythema dose) 99 Korean ancestry individuals 112 Korean ancestry individuals Affymetrix [506945] 0 minimal erythema dose http://www.ebi.ac.uk/efo/EFO_0007639 GCST003024 Genome-wide genotyping array 99 2016-09-12 26325155 Brehm JM 2015-09-01 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/26325155 A Genome-Wide Association Study of Post-bronchodilator Lung Function in Children with Asthma. Post-bronchodilator lung function in asthma (FEV1) 447 Puerto Rican ancestry cases 568 European, black or Hispanic cases, 2,414 Hispanic cases Illumina [NR] 0 pulmonary function measurement, forced expiratory volume, response to bronchodilator http://www.ebi.ac.uk/efo/EFO_0003892, http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366 GCST003110 Genome-wide genotyping array 447 2016-09-12 26325155 Brehm JM 2015-09-01 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/26325155 A Genome-Wide Association Study of Post-bronchodilator Lung Function in Children with Asthma. Post-bronchodilator lung function in asthma (FEV1/FVC) 447 Puerto Rican ancestry cases 568 European, black or Hispanic cases, 2,414 Hispanic cases Illumina [NR] 0 pulmonary function measurement, response to bronchodilator, FEV/FEC ratio http://www.ebi.ac.uk/efo/EFO_0003892, http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713 GCST003107 Genome-wide genotyping array 447 2016-04-23 22550155 Edelstein LC 2012-05-01 Circulation www.ncbi.nlm.nih.gov/pubmed/22550155 Human genome-wide association and mouse knockout approaches identify platelet supervillin as an inhibitor of thrombus formation under shear stress. Platelet thrombus formation 125 European ancestry individuals, 116 African American individuals NA Illumina [at least 620901] 6 platelet reactivity measurement, thrombus formation measurement http://www.ebi.ac.uk/efo/EFO_0004985, http://www.ebi.ac.uk/efo/EFO_0007615 GCST001501 Genome-wide genotyping array 241 2016-08-31 26301688 Li YR 2015-08-24 Nat Med www.ncbi.nlm.nih.gov/pubmed/26301688 Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. Pediatric autoimmune diseases 97 European ancestry thyroiditis cases, 107 European ancestry ankylosing spondylitis cases, 100 European ancestry psoriasis cases, 173 European ancestry celiac disease cases, 254 European ancestry systemic lupus erythematosus cases, 308 European ancestry common variable inmunodeficiency cases, 865 European ancestry ulcerative colitis cases, 1,086 European ancestry Type 1 diabetes cases, 1,123 European ancestry juvenile idiopathic arthritis cases, 1,922 European ancestry Crohn's disease cases, 10,718 European ancestry controls NA Illumina [7347414] (imputed) 46 autoimmune thyroid disease, type I diabetes mellitus, Common variable immunodeficiency, ankylosing spondylitis, psoriasis, celiac disease, ulcerative colitis, Crohn's disease, autoimmune disease, juvenile idiopathic arthritis, systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0006812, http://www.ebi.ac.uk/efo/EFO_0001359, http://www.orpha.net/ORDO/Orphanet_1572, http://www.ebi.ac.uk/efo/EFO_0003898, http://www.ebi.ac.uk/efo/EFO_0000676, http://www.ebi.ac.uk/efo/EFO_0001060, http://www.ebi.ac.uk/efo/EFO_0000729, http://www.ebi.ac.uk/efo/EFO_0000384, http://www.ebi.ac.uk/efo/EFO_0005140, http://www.ebi.ac.uk/efo/EFO_0002609, http://www.ebi.ac.uk/efo/EFO_0002690 GCST003097 Genome-wide genotyping array 16754 2016-08-31 26312577 Tan LJ 2015-08-27 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/26312577 Bivariate Genome-Wide Association Study Implicates ATP6V1G1 as a Novel Pleiotropic Locus Underlying Osteoporosis and Age at Menarche. Bone mineral density (spine) and age at menarche 826 Han Chinese ancestry females 1,728 European ancestry females, 709 African American females, 408 Hispanic/Latin American females Affymetrix [702413] 9 age at menarche, spine bone mineral density http://www.ebi.ac.uk/efo/EFO_0004703, http://www.ebi.ac.uk/efo/EFO_0007701 GCST003101 Genome-wide genotyping array 826 2016-09-07 26312577 Tan LJ 2015-08-27 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/26312577 Bivariate Genome-Wide Association Study Implicates ATP6V1G1 as a Novel Pleiotropic Locus Underlying Osteoporosis and Age at Menarche. Bone mineral density (hip) and age at menarche 826 Han Chinese ancestry females 1,728 European ancestry females, 709 African American females, 408 Hispanic/Latin American females Affymetrix [702413] 8 hip bone mineral density, age at menarche http://www.ebi.ac.uk/efo/EFO_0007702, http://www.ebi.ac.uk/efo/EFO_0004703 GCST003102 Genome-wide genotyping array 826 2016-06-29 26339675 Tosto G 2015-06-18 Ann Clin Transl Neurol www.ncbi.nlm.nih.gov/pubmed/26339675 F-box/LRR-repeat protein 7 is genetically associated with Alzheimer's disease. Alzheimer's disease (late onset) 2,451 Caribbean Hispanic cases, 2,063 Caribbean Hispanic controls 550 Caribbean Hispanic cases, 236 Caribbean Hispanic controls Affymetrix, Illumina [8837542] (imputed) 3 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST002983 Genome-wide genotyping array 4514 2016-09-06 26362575 van den Berg SM 2015-09-11 Behav Genet www.ncbi.nlm.nih.gov/pubmed/26362575 Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium. Extraversion 63,030 European ancestry individuals 9,783 European ancestry individuals Affymetrix, Illumina, Perlegen [6941603] (imputed) 0 extraversion http://www.ebi.ac.uk/efo/EFO_0004317 GCST003120 Genome-wide genotyping array 63030 2016-04-12 26289589 Nishizawa D 2015-08-20 Mol Brain www.ncbi.nlm.nih.gov/pubmed/26289589 Associations between the orexin (hypocretin) receptor 2 gene polymorphism Val308Ile and nicotine dependence in genome-wide and subsequent association studies. Nicotine dependence 148 Japanese ancestry individuals 374 Japanese ancestry individuals Illumina [225591] 0 nicotine dependence http://www.ebi.ac.uk/efo/EFO_0003768 GCST003093 Genome-wide genotyping array 148 2016-06-17 26299439 Li WD 2015-08-24 Sci Rep www.ncbi.nlm.nih.gov/pubmed/26299439 Pathway-Based Genome-wide Association Studies Reveal That the Rac1 Pathway Is Associated with Plasma Adiponectin Levels. Adiponectin levels 737 European ancestry females NA Illumina [up to 550000] 5 adiponectin measurement http://www.ebi.ac.uk/efo/EFO_0004502 GCST003096 Genome-wide genotyping array 737 2016-09-12 26299439 Li WD 2015-08-24 Sci Rep www.ncbi.nlm.nih.gov/pubmed/26299439 Pathway-Based Genome-wide Association Studies Reveal That the Rac1 Pathway Is Associated with Plasma Adiponectin Levels. Adiponectin levels (BMI-adjusted) 737 European ancestry females NA Illumina [up to 550000] 4 BMI-adjusted adiponectin measurement http://www.ebi.ac.uk/efo/EFO_0007737 GCST003095 Genome-wide genotyping array 737 2016-09-19 26433129 Tin A 2015-10-03 Diabet Med www.ncbi.nlm.nih.gov/pubmed/26433129 GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study. Plasma lactate levels 6,901 European ancestry individuals 1,671 African American individuals Affymetrix [~ 38000000] (imputed) 4 lactate measurement http://www.ebi.ac.uk/efo/EFO_0007745 GCST003147 Genome-wide genotyping array 6901 2016-09-21 26366535 Sood RF 2015-10-01 Ann Surg www.ncbi.nlm.nih.gov/pubmed/26366535 Genome-wide Association Study of Postburn Scarring Identifies a Novel Protective Variant. Postburn hypertrophic scarring severity 408 European ancestry individuals, 26 Asian ancestry individuals, 19 African American individuals, 11 Native American ancestry individuals, 74 individuals NA Illumina [289639] 1 postburn hypertrophic scarring severity measurement http://www.ebi.ac.uk/efo/EFO_0007747 GCST003146 Genome-wide genotyping array 538 2016-09-06 26343869 Xie G 2015-09-05 Atherosclerosis www.ncbi.nlm.nih.gov/pubmed/26343869 Genome-wide association study on progression of carotid artery intima media thickness over 10 years in a Chinese cohort. Carotid intima media thickness 810 Chinese ancestry individuals NA Illumina [32817] 12 carotid artery intima media thickness http://www.ebi.ac.uk/efo/EFO_0007117 GCST003114 Genome-wide genotyping array 810 2016-09-12 26343387 Nikpay M 2015-09-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26343387 A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease. Coronary artery disease 42,096 European ancestry cases, 361 African American cases, 758 Hispanic American cases, 12,658 South Asian ancestry cases, 1,802 Lebanese ancestry cases, 3,614 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls NA Affymetrix, Illumina [8600000] (imputed) 45 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST003116 Genome-wide genotyping array 187599 2016-09-12 26343387 Nikpay M 2015-09-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26343387 A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease. Myocardial infarction 27,509 European ancestry cases, 130 African American cases, 278 Hispanic American cases, 10,257 South Asian ancestry cases, 288 Lebanese ancestry cases, 1,687 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls NA Affymetrix, Illumina [8600000] (imputed) 38 myocardial infarction http://www.ebi.ac.uk/efo/EFO_0000612 GCST003117 Genome-wide genotyping array 166459 2016-09-06 26433762 Liu X 2015-09-25 J Affect Disord www.ncbi.nlm.nih.gov/pubmed/26433762 A genome-wide association study of bipolar disorder with comorbid eating disorder replicates the SOX2-OT region. Eating disorder in bipolar disorder 184 European ancestry cases, 2,006 European ancestry controls NA Affymetrix [703012] 5 eating disorder http://www.ebi.ac.uk/efo/EFO_0005203 GCST003132 Genome-wide genotyping array 2190 2016-09-06 26433762 Liu X 2015-09-25 J Affect Disord www.ncbi.nlm.nih.gov/pubmed/26433762 A genome-wide association study of bipolar disorder with comorbid eating disorder replicates the SOX2-OT region. Bipolar disorder and eating disorder 184 European ancestry cases with bipolar disorder and eating disorder, 1,370 European ancestry controls NA Affymetrix [703012] 10 eating disorder, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0005203, http://www.ebi.ac.uk/efo/EFO_0000289 GCST003135 Genome-wide genotyping array 1554 2016-09-06 26433762 Liu X 2015-09-25 J Affect Disord www.ncbi.nlm.nih.gov/pubmed/26433762 A genome-wide association study of bipolar disorder with comorbid eating disorder replicates the SOX2-OT region. Bipolar disorder 2,006 European ancestry bipolar disorder without eating disorder cases, 1,370 European ancestry controls NA Affymetrix [703012] 0 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST003136 Genome-wide genotyping array 3376 2016-10-05 26434682 Lin YJ 2015-11-01 Sci Rep www.ncbi.nlm.nih.gov/pubmed/26434682 Genetic variants in PLCB4/PLCB1 as susceptibility loci for coronary artery aneurysm formation in Kawasaki disease in Han Chinese in Taiwan. Coronary artery aneurysm in Kawasaki disease 76 Han Chinese ancestry child cases, 186 Han Chinese ancestry child controls NA Affymetrix [906600] 2 coronary aneurysm http://www.ebi.ac.uk/efo/EFO_1000881 GCST003192 Genome-wide genotyping array 262 2016-09-19 26451028 Hofer E 2015-10-08 Stroke www.ncbi.nlm.nih.gov/pubmed/26451028 White Matter Lesion Progression: Genome-Wide Search for Genetic Influences. White matter lesion progression 1,085 European ancestry elderly cases, 6,688 European ancestry elderly controls NA Affymetrix, Illumina [up to 2543887] (imputed) 7 white matter lesion progression measurement http://www.ebi.ac.uk/efo/EFO_0007746 GCST003151 Genome-wide genotyping array 7773 2016-09-19 26451028 Hofer E 2015-10-08 Stroke www.ncbi.nlm.nih.gov/pubmed/26451028 White Matter Lesion Progression: Genome-Wide Search for Genetic Influences. White matter lesion progression (adjusted for white matter lesion burden at baseline) 1,085 European ancestry elderly cases, 6,688 European ancestry elderly controls NA Affymetrix, Illumina [up to 2543887] (imputed) 6 white matter lesion progression measurement http://www.ebi.ac.uk/efo/EFO_0007746 GCST003152 Genome-wide genotyping array 7773 2016-09-12 26421299 Li J 2015-09-03 Biomed Res Int www.ncbi.nlm.nih.gov/pubmed/26421299 Genetic Interactions Explain Variance in Cingulate Amyloid Burden: An AV-45 PET Genome-Wide Association and Interaction Study in the ADNI Cohort. Cingulate cortical amyloid beta load 215 European ancestry early mild cognitive impairment cases, 152 European ancestry late mild cognitive impairment cases, 45 European ancestry Alzheimer disease cases, 190 European ancestry controls NA Illumina [582718] 5 amyloid-beta measurement, cingulate cortex measurement http://www.ebi.ac.uk/efo/EFO_0005194, http://www.ebi.ac.uk/efo/EFO_0007738 GCST003113 Genome-wide genotyping array 602 2016-09-07 26416757 Band G 2015-09-30 Nature www.ncbi.nlm.nih.gov/pubmed/26416757 A novel locus of resistance to severe malaria in a region of ancient balancing selection. Severe malaria 5,130 African ancestry cases, 5,291 African ancestry controls 5,535 African ancestry cases, 9,948 African ancestry controls Illumina [~ 38000000] (imputed) 3 malaria http://www.ebi.ac.uk/efo/EFO_0001068 GCST003145 Genome-wide genotyping array 10421 2016-09-19 26417704 Corvol H 2015-09-29 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26417704 Genome-wide association meta-analysis identifies five modifier loci of lung disease severity in cystic fibrosis. Lung disease severity in cystic fibrosis 4,139 European and other ancestry p.Phe508del homozygote cases, 2,226 European and other ancestry cases NA Illumina [8520458] (imputed) 29 lung disease associated with cystic fibrosis http://www.ebi.ac.uk/efo/EFO_0009797 GCST003143 Genome-wide genotyping array 6873 2016-09-19 26450422 DeLorenze GN 2015-10-08 J Infect Dis www.ncbi.nlm.nih.gov/pubmed/26450422 Polymorphisms in HLA Class II Genes Are Associated With Susceptibility to Staphylococcus aureus Infection in a White Population. Staphylococcus aureus infection 4,701 European ancestry cases, 45,344 European ancestry controls NA Affymetrix [at least 584535] (imputed) 2 Staphylococcus aureus infection http://www.ebi.ac.uk/efo/EFO_0005681 GCST003150 Genome-wide genotyping array 50045 2016-09-19 26450422 DeLorenze GN 2015-10-08 J Infect Dis www.ncbi.nlm.nih.gov/pubmed/26450422 Polymorphisms in HLA Class II Genes Are Associated With Susceptibility to Staphylococcus aureus Infection in a White Population. Skin and soft tissue Staphylococcus aureus infection 2,130 European ancestry cases, 45,434 European ancestry controls NA Affymetrix [at least 584535] (imputed) 1 skin and soft tissue Staphylococcus aureus infection http://www.ebi.ac.uk/efo/EFO_1001489 GCST003149 Genome-wide genotyping array 47564 2016-05-17 26075790 Kelemen LE 2015-06-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26075790 Genome-wide significant risk associations for mucinous ovarian carcinoma. Mucinous ovarian carcinoma 1,003 European ancestry invasive cases, 641 European ancestry low malignant potential cases, 21,693 European ancestry controls NA Illumina [15504273] (imputed) 6 ovarian mucinous adenocarcinoma http://www.ebi.ac.uk/efo/EFO_0006462 GCST002967 Genome-wide genotyping array 23337 2016-06-13 26081443 Adkins DE 2015-06-17 Twin Res Hum Genet www.ncbi.nlm.nih.gov/pubmed/26081443 Genome-Wide Meta-Analysis of Longitudinal Alcohol Consumption Across Youth and Early Adulthood. Longitudinal alcohol consumption 2,126 adolescents and early adults NA Illumina [866099] (imputed) 6 longitudinal alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0007645 GCST002981 Genome-wide genotyping array 2126 2016-10-14 26077402 de Rooy DP 2015-06-15 J Rheumatol www.ncbi.nlm.nih.gov/pubmed/26077402 Genetic Factors for the Severity of ACPA-negative Rheumatoid Arthritis in 2 Cohorts of Early Disease: A Genome-wide Study. Joint damage progression in ACPA-negative rheumatoid arthritis 262 Western European ancestry cases 253 Western European ancestry cases Illumina [244624] 1 joint damage measurement http://www.ebi.ac.uk/efo/EFO_0005413 GCST003256 Genome-wide genotyping array 262 2016-07-08 26089329 Carty CL 2015-06-18 Stroke www.ncbi.nlm.nih.gov/pubmed/26089329 Meta-Analysis of Genome-Wide Association Studies Identifies Genetic Risk Factors for Stroke in African Americans. Ischemic stroke up to 1,365 African American cases, up to 13,154 African American controls European ancestry individuals (see Traylor, 2012) Affymetrix, Illumina [~ 2600000] (imputed) 9 Ischemic stroke http://purl.obolibrary.org/obo/HP_0002140 GCST002988 Genome-wide genotyping array 14519 2016-07-08 26089329 Carty CL 2015-06-18 Stroke www.ncbi.nlm.nih.gov/pubmed/26089329 Meta-Analysis of Genome-Wide Association Studies Identifies Genetic Risk Factors for Stroke in African Americans. Stroke up to 1,592 African American cases, up to 13,154 African American controls NA Affymetrix, Illumina [up to 2600000] (imputed) 27 stroke http://www.ebi.ac.uk/efo/EFO_0000712 GCST002987 Genome-wide genotyping array 14746 2016-04-23 26100964 Cao S 2015-06-23 Sci Rep www.ncbi.nlm.nih.gov/pubmed/26100964 Genome-wide Association Study on Platinum-induced Hepatotoxicity in Non-Small Cell Lung Cancer Patients. Platinum-induced hepatotoxicity in non-small cell lung cancer 329 Han Chinese ancestry cases 375 Han Chinese ancestry cases Affymetrix [588732] 0 response to platinum based chemotherapy, drug-induced liver injury http://www.ebi.ac.uk/efo/EFO_0004647, http://www.ebi.ac.uk/efo/EFO_0004228 GCST002993 Genome-wide genotyping array 329 2016-06-08 26083242 Dahlin A 2015-06-17 PLoS One www.ncbi.nlm.nih.gov/pubmed/26083242 Genome-Wide Association Study Identifies Novel Pharmacogenomic Loci For Therapeutic Response to Montelukast in Asthma. Response to montelukast in asthma (change in FEV1) 88 European ancestry cases, 10 African ancestry cases, 35 Asian ancestry cases 101 European ancestry cases, 33 African ancestry cases, 50 Asian ancestry cases Illumina [532264] 2 FEV change measurement, response to montelukast http://www.ebi.ac.uk/efo/EFO_0005921, http://www.ebi.ac.uk/efo/EFO_0007612 GCST002979 Genome-wide genotyping array 133 2016-06-21 26098869 Childs EJ 2015-06-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26098869 Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer. Pancreatic cancer 7,638 cases, 7,364 controls 2,287 cases, 4,205 controls Illumina [866891] (imputed) 17 pancreatic carcinoma http://www.ebi.ac.uk/efo/EFO_0002618 GCST002991 Genome-wide genotyping array 15002 2016-07-14 26098866 Helgason H 2015-06-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26098866 Loss-of-function variants in ATM confer risk of gastric cancer. Gastric cancer 2,500 European ancestry cases, 205,652 European ancestry controls (includes non-array genotyped, whole genome imputed individuals) NA Illumina [~ 25000000] (imputed) 8 gastric carcinoma http://www.ebi.ac.uk/efo/EFO_0000178 GCST002992 Genome-wide genotyping array 208152 2016-07-14 26098866 Helgason H 2015-06-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26098866 Loss-of-function variants in ATM confer risk of gastric cancer. Gastric adenocarcinoma (histologically verified) 2,043 European ancestry cases, 202,533 European ancestry controls NA Illumina [~ 25000000] (imputed) 7 gastric adenocarcinoma http://www.ebi.ac.uk/efo/EFO_0000503 GCST002990 Genome-wide genotyping array 204576 2016-06-08 26079190 Galfalvy H 2015-06-16 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/26079190 A genome-wide association study of suicidal behavior. Suicide behavior 577 European ancestry cases, 1,233 European ancestry controls NA Illumina [794207] 5 suicide behaviour http://www.ebi.ac.uk/efo/EFO_0007623 GCST002969 Genome-wide genotyping array 1810 2016-06-08 26079190 Galfalvy H 2015-06-16 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/26079190 A genome-wide association study of suicidal behavior. Suicide ideation score in major depressive disorder 358 European ancestry individuals NA Illumina [794207] 3 suicide ideation measurement http://www.ebi.ac.uk/efo/EFO_0007619 GCST002974 Genome-wide genotyping array 358 2016-06-08 26079190 Galfalvy H 2015-06-16 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/26079190 A genome-wide association study of suicidal behavior. Suicide 317 European ancestry cases, 1,233 European ancestry controls NA Illumina [794207] 3 suicide http://www.ebi.ac.uk/efo/EFO_0007624 GCST002973 Genome-wide genotyping array 1550 2016-06-08 26079190 Galfalvy H 2015-06-16 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/26079190 A genome-wide association study of suicidal behavior. Suicide attempts in major depressive disorder 257 European ancestry cases, 300 European ancestry controls NA Illumina [794207] 1 attempted suicide http://www.ebi.ac.uk/efo/EFO_0004321 GCST002972 Genome-wide genotyping array 557 2016-04-26 26083729 Maruthur NM 2015-06-17 PLoS One www.ncbi.nlm.nih.gov/pubmed/26083729 Genetics of Plasma Soluble Receptor for Advanced Glycation End-Products and Cardiovascular Outcomes in a Community-based Population: Results from the Atherosclerosis Risk in Communities Study. Advanced glycation end-product levels 581 Black individuals, 1,737 European ancestry individuals NA Affymetrix [up to 9100000] (imputed) 2 sRAGE measurement http://www.ebi.ac.uk/efo/EFO_0007622 GCST002977 Genome-wide genotyping array 2318 2016-06-17 26545630 Deming Y 2015-09-25 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/26545630 A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin. Cerebrospinal fluid clusterin levels 300 Alzheimer's disease cases, 373 controls NA Illumina [5970354] (imputed) 24 cerebrospinal fluid clusterin measurement http://www.ebi.ac.uk/efo/EFO_0007657 GCST003134 Genome-wide genotyping array 673 2016-06-17 26545630 Deming Y 2015-09-25 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/26545630 A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin. Plasma clusterin levels 521 Alzheimer's disease cases, 297 controls NA Illumina [5970354] (imputed) 15 plasma clusterin measurement http://www.ebi.ac.uk/efo/EFO_0007656 GCST003133 Genome-wide genotyping array 818 2016-06-17 26545630 Deming Y 2015-09-25 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/26545630 A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin. Cerebrospinal fluid clusterin levels in APOEe4- carriers 123 Alzheimer's disease cases, 270 controls NA Illumina [5970354] (imputed) 1 cerebrospinal fluid clusterin measurement http://www.ebi.ac.uk/efo/EFO_0007657 GCST003137 Genome-wide genotyping array 393 2016-06-17 26545630 Deming Y 2015-09-25 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/26545630 A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin. Cerebrospinal fluid clusterin levels in APOEe4+ carriers 177 Alzheimer's disease cases, 103 controls NA Illumina [5970354] (imputed) 1 cerebrospinal fluid clusterin measurement http://www.ebi.ac.uk/efo/EFO_0007657 GCST003131 Genome-wide genotyping array 280 2016-10-04 26516778 Bis JC 2015-10-30 PLoS One www.ncbi.nlm.nih.gov/pubmed/26516778 Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium. Cardiovascular disease in hypertension (ACE inhibitor interaction) Up to 3,527 European ancestry individuals with cardiovascular disease, up to 11,848 European ancestry individuals without cardiovascular disease Up to 1,751 European ancestry individuals with cardiovascular disease, up to 1,267 African American ancestry individuals with cardiovascular disease, up to 2,874 African American ancestry individuals without cardiovascular disease Affymetrix, Illumina [1892626] (imputed) 1 cardiovascular disease, response to angiotensin-converting enzyme inhibitor http://www.ebi.ac.uk/efo/EFO_0000319, http://www.ebi.ac.uk/efo/EFO_0005325 GCST003186 Genome-wide genotyping array 15375 2016-10-06 26516778 Bis JC 2015-10-30 PLoS One www.ncbi.nlm.nih.gov/pubmed/26516778 Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium. Cardiovascular disease in hypertension (calcium channel blocker interaction) Up to 3,527 European ancestry individuals with cardiovascular disease, up to 11,848 European ancestry individuals without cardiovascular disease Up to 1,751 European ancestry individuals with cardiovascular disease, up to 1,267 African American ancestry individuals with cardiovascular disease, up to 2,874 African American ancestry individuals without cardiovascular disease Affymetrix, Illumina [1807456] (imputed) 2 cardiovascular disease, response to calcium channel blocker http://www.ebi.ac.uk/efo/EFO_0000319, http://www.ebi.ac.uk/efo/EFO_0007767 GCST003205 Genome-wide genotyping array 15375 2016-10-06 26516778 Bis JC 2015-10-30 PLoS One www.ncbi.nlm.nih.gov/pubmed/26516778 Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium. Myocardial infarction in hypertension (calcium channel blocker interaction) Up to 2,114 European ancestry individuals with myocardial infarction, up to 13,261 European ancestry individuals without myocardial infarction Up to 1,171 European ancestry individuals with myocardial infarction Affymetrix, Illumina [1194322] (imputed) 1 response to calcium channel blocker, myocardial infarction http://www.ebi.ac.uk/efo/EFO_0007767, http://www.ebi.ac.uk/efo/EFO_0000612 GCST003206 Genome-wide genotyping array 15375 2016-10-06 26516778 Bis JC 2015-10-30 PLoS One www.ncbi.nlm.nih.gov/pubmed/26516778 Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium. Cardiovascular disease in hypertension (diuretic interaction) Up to 3,527 European ancestry individuals with cardiovascular disease, up to 11,848 European ancestry individuals without cardiovascular disease Up to 1,751 European ancestry individuals with cardiovascular disease, up to 1,267 African American ancestry individuals with cardiovascular disease, up to 2,874 African American ancestry individuals without cardiovascular disease Affymetrix, Illumina [2030893] (imputed) 0 response to diuretic, cardiovascular disease http://purl.obolibrary.org/obo/GO_0036270, http://www.ebi.ac.uk/efo/EFO_0000319 GCST003204 Genome-wide genotyping array 15375 2016-10-06 26516778 Bis JC 2015-10-30 PLoS One www.ncbi.nlm.nih.gov/pubmed/26516778 Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium. Cardiovascular disease in hypertension (beta blocker interaction) Up to 3,527 European ancestry individuals with cardiovascular disease, up to 11,848 European ancestry individuals without cardiovascular disease Up to 1,751 European ancestry individuals with cardiovascular disease, up to 1,267 African American ancestry individuals with cardiovascular disease, up to 2,874 African American ancestry individuals without cardiovascular disease Affymetrix, Illumina [1971049] (imputed) 0 response to beta blocker, cardiovascular disease http://www.ebi.ac.uk/efo/EFO_0007766, http://www.ebi.ac.uk/efo/EFO_0000319 GCST003203 Genome-wide genotyping array 15375 2016-10-04 26516778 Bis JC 2015-10-30 PLoS One www.ncbi.nlm.nih.gov/pubmed/26516778 Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium. Myocardial infarction in hypertension (ACE inhibitor interaction) Up to 2,114 European ancestry individuals with myocardial infarction, up to 13,261 European ancestry individuals without myocardial infarction Up to 1,171 European ancestry individuals with myocardial infarction Affymetrix, Illumina [1465692] (imputed) 0 response to angiotensin-converting enzyme inhibitor, myocardial infarction http://www.ebi.ac.uk/efo/EFO_0005325, http://www.ebi.ac.uk/efo/EFO_0000612 GCST003187 Genome-wide genotyping array 15375 2016-10-06 26516778 Bis JC 2015-10-30 PLoS One www.ncbi.nlm.nih.gov/pubmed/26516778 Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium. Myocardial infarction in hypertension (beta blocker interaction) Up to 2,114 European ancestry individuals with myocardial infarction, up to 13,261 European ancestry individuals without myocardial infarction Up to 1,171 European ancestry individuals with myocardial infarction Affymetrix, Illumina [1780479] (imputed) 0 response to beta blocker, myocardial infarction http://www.ebi.ac.uk/efo/EFO_0007766, http://www.ebi.ac.uk/efo/EFO_0000612 GCST003201 Genome-wide genotyping array 15375 2016-10-06 26516778 Bis JC 2015-10-30 PLoS One www.ncbi.nlm.nih.gov/pubmed/26516778 Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium. Myocardial infarction in hypertension (diuretic interaction) Up to 2,114 European ancestry individuals with myocardial infarction, up to 13,261 European ancestry individuals myocardial infarction Up to 1,171 European ancestry individuals with myocardial infarction Affymetrix, Illumina [1822485] (imputed) 0 response to diuretic, myocardial infarction http://purl.obolibrary.org/obo/GO_0036270, http://www.ebi.ac.uk/efo/EFO_0000612 GCST003202 Genome-wide genotyping array 15375 2016-10-14 26562150 Seldin MF 2015-10-10 Mol Med www.ncbi.nlm.nih.gov/pubmed/26562150 Genome-wide Association Study of Late-Onset Myasthenia Gravis: Confirmation of TNFRSF11A, and Identification of ZBTB10 and Three Distinct HLA Associations. Late-onset myasthenia gravis 532 European ancestry cases, 2,128 European ancestry controls NA Illumina [6175472] (imputed) 21 late-onset myasthenia gravis http://www.ebi.ac.uk/efo/EFO_1001490 GCST003251 Genome-wide genotyping array 2660 2016-10-05 26561523 de Vries PS 2015-11-10 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26561523 A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration. Fibrinogen levels 120,246 European ancestry individuals NA Affymetrix, Illumina [~ 10700000] (imputed) 41 fibrinogen measurement http://www.ebi.ac.uk/efo/EFO_0004623 GCST003194 Genome-wide genotyping array 120246 2016-10-12 26546620 Xu CF 2015-11-06 Clin Cancer Res www.ncbi.nlm.nih.gov/pubmed/26546620 HLA-B*57:01 Confers Susceptibility to Pazopanib-Associated Liver Injury in Patients with Cancer. Response to Pazopanib in cancer (hepatotoxicity) Up to 844 European ancestry cases, up to 325 Asian ancestry cases, up to 19 cases Up to 811 European ancestry cases, up to 114 Asian ancestry cases, up to 77 cases Illumina [6736730] (imputed) 1 response to pazopanib, serum alanine aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0007779, http://www.ebi.ac.uk/efo/EFO_0004735 GCST003232 Genome-wide genotyping array 1188 2016-01-15 26114229 Ashley-Koch AE 2015-06-12 J Affect Disord www.ncbi.nlm.nih.gov/pubmed/26114229 Genome-wide association study of posttraumatic stress disorder in a cohort of Iraq-Afghanistan era veterans. Post-traumatic stress disorder 949 non-Hispanic black individuals, 759 European ancestry individuals NA Illumina [up to 5616481] (imputed) 9 post-traumatic stress disorder http://www.ebi.ac.uk/efo/EFO_0001358 GCST002963 Genome-wide genotyping array 1708 2016-07-11 26112879 Rudkowska I 2015-06-20 J Nutrigenet Nutrigenomics www.ncbi.nlm.nih.gov/pubmed/26112879 Interaction between Common Genetic Variants and Total Fat Intake on Low-Density Lipoprotein Peak Particle Diameter: A Genome-Wide Association Study. LDL peak particle diameter (total fat intake interaction) 541 European ancestry individuals NA Illumina [1632371] (imputed) 21 LDL peak particle diameter measurement, total fat intake measurement http://www.ebi.ac.uk/efo/EFO_0007677, http://www.ebi.ac.uk/efo/EFO_0007678 GCST002989 Genome-wide genotyping array 541 2016-06-08 26116289 Raginis-Zborowska A 2015-06-24 Exp Gerontol www.ncbi.nlm.nih.gov/pubmed/26116289 Genetic determinants of swallowing impairments among community dwelling older population. Dysphagia 71 European ancestry older adult cases, 484 European ancestry older adult controls NA Illumina [4196861] (imputed) 19 Dysphagia http://purl.obolibrary.org/obo/HP_0002015 GCST002995 Genome-wide genotyping array 555 2016-06-10 26151821 Schumacher FR 2015-07-07 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26151821 Genome-wide association study of colorectal cancer identifies six new susceptibility loci. Colorectal cancer 18,299 European ancestry cases, 19,656 European ancestry controls 4,725 East Asian ancestry cases, 9,969 East Asian ancestry controls Affymetrix, Illumina [~ 2500000] (imputed) 22 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST003017 Genome-wide genotyping array 37955 2016-07-13 26121980 Chauhan L 2015-06-30 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/26121980 Genome-wide association analysis identified splicing single nucleotide polymorphism in CFLAR predictive of triptolide chemo-sensitivity. Triptolide cytotoxicity 55 European ancestry lymphoblastoid cell lines NA Affymetrix, Illumina, Perlegen [at least 1978803] (imputed) 16 response to triptolide, cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0007662, http://www.ebi.ac.uk/efo/EFO_0006952 GCST003008 Genome-wide genotyping array 55 2016-04-28 26154020 Ferrari R 2015-06-12 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/26154020 A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia. Frontotemporal dementia 530 European ancestry cases, 926 European ancestry controls NA Illumina [2292247] (imputed) 9 Frontotemporal dementia http://www.orpha.net/ORDO/Orphanet_282 GCST002960 Genome-wide genotyping array 1456 2016-08-22 26307654 Szulkin R 2015-08-25 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/26307654 Genome-wide association study of prostate cancer-specific survival. Prostate cancer (survival) 7,322 cases 18,197 European ancestry cases Affymetrix, Illumina [up to 9536409] (imputed) 4 survival time, prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0000714, http://www.ebi.ac.uk/efo/EFO_0001663 GCST003100 Genome-wide genotyping array 7322 2016-11-29 26806518 Hou L 2016-01-22 Lancet www.ncbi.nlm.nih.gov/pubmed/26806518 Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study. Response to lithium treatment in bipolar disorder (dichotomous phenotype) 659 European ancestry responders, 44 East Asian ancestry responders, 1,684 European ancestry non-responders, 176 East Asian ancestry non-responders NA Affymetrix, Illumina [> 6000000] (imputed) 1 response to lithium ion http://purl.obolibrary.org/obo/GO_0010226 GCST003378 Genome-wide genotyping array 2563 2021-10-15 26806518 Hou L 2016-01-22 Lancet www.ncbi.nlm.nih.gov/pubmed/26806518 Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study. Response to lithium treatment in bipolar disorder (continuous phenotype) 2,039 European ancestry individuals NA Affymetrix, Illumina [> 6000000] (imputed) 4 response to lithium ion http://purl.obolibrary.org/obo/GO_0010226 GCST012487 Genome-wide genotyping array 2039 2021-10-15 26806518 Hou L 2016-01-22 Lancet www.ncbi.nlm.nih.gov/pubmed/26806518 Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study. Response to lithium treatment in bipolar disorder (dichotomous phenotype) 659 European ancestry responders, 1,684 European ancestry non-responders NA Affymetrix, Illumina [> 6000000] (imputed) 3 response to lithium ion http://purl.obolibrary.org/obo/GO_0010226 GCST012486 Genome-wide genotyping array 2343 2021-05-27 26806518 Hou L 2016-01-22 Lancet www.ncbi.nlm.nih.gov/pubmed/26806518 Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study. Response to lithium treatment in bipolar disorder (continuous phenotype) 2,039 European ancestry individuals, 194 East Asian ancestry individuals NA Affymetrix, Illumina [> 6000000] (imputed) 2 response to lithium ion http://purl.obolibrary.org/obo/GO_0010226 GCST011750 Genome-wide genotyping array 2233 2016-11-30 26805783 Schick UM 2016-01-21 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/26805783 Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans. Platelet count 12,491 Hispanic/Latin American individuals 7,170 Hispanic/Latin American individuals Illumina [2232944] (imputed) 13 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST003383 Genome-wide genotyping array 12491 2016-09-27 26632684 Dong J 2015-11-01 Medicine (Baltimore) www.ncbi.nlm.nih.gov/pubmed/26632684 Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults. Sense of smell 6,252 European ancestry individuals NA Affymetrix, Illumina [2543887] (imputed) 22 sensory perception of smell http://purl.obolibrary.org/obo/GO_0007608 GCST003174 Genome-wide genotyping array 6252 2016-11-18 26815016 Julia A 2016-01-27 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/26815016 Identification of IRX1 as a Risk Locus for Rheumatoid Factor Positivity in Rheumatoid Arthritis in a Genome-Wide Association Study. Rheumatoid factor seropositivity in rheumatoid arthritis 896 Spanish ancestry rheumatoid factor-positive cases, 282 Spanish ancestry rheumatoid factor-negative cases 472 Spanish ancestry rheumatoid factor-positive cases, 190 Spanish ancestry rheumatoid factor-negative cases Illumina [509374] 1 rheumatoid factor seropositivity measurement, rheumatoid factor measurement http://www.ebi.ac.uk/efo/EFO_0007791, http://www.ebi.ac.uk/efo/EFO_0005767 GCST003330 Genome-wide genotyping array 1178 2016-12-01 27015805 Pilling LC 2016-03-23 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/27015805 Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants. Parental longevity (father's age at death) 63,775 British middle-aged individuals 2,033 individuals Affymetrix [9678092] (imputed) 0 parental longevity http://www.ebi.ac.uk/efo/EFO_0007796 GCST003392 Genome-wide genotyping array 63775 2016-12-01 27015805 Pilling LC 2016-03-23 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/27015805 Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants. Parental longevity (mother's age at death) 52,776 middle-aged British individuals NA Affymetrix [9658292] (imputed) 51 parental longevity http://www.ebi.ac.uk/efo/EFO_0007796 GCST003393 Genome-wide genotyping array 52776 2016-12-01 27015805 Pilling LC 2016-03-23 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/27015805 Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants. Parental longevity (combined parental age at death) 45,627 middle-aged British individuals NA Affymetrix [9658292] (imputed) 51 parental longevity http://www.ebi.ac.uk/efo/EFO_0007796 GCST003394 Genome-wide genotyping array 45627 2016-12-01 27015805 Pilling LC 2016-03-23 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/27015805 Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants. Parental extreme longevity (95 years and older) 1,339 middle-aged British cases, 40,934 middle-aged British controls NA Affymetrix [9658292] (imputed) 73 parental longevity http://www.ebi.ac.uk/efo/EFO_0007796 GCST003395 Genome-wide genotyping array 42273 2016-10-07 26582766 Lu X 2015-11-18 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/26582766 Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations. Cholesterol, total 8,344 Han Chinese ancestry individuals 14,739 Han Chinese ancestry individuals Affymetrix, Illumina [2573667] (imputed) 14 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST003214 Genome-wide genotyping array 8344 2016-10-07 26582766 Lu X 2015-11-18 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/26582766 Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations. LDL cholesterol 8,344 Han Chinese ancestry individuals 14,739 Han Chinese ancestry individuals Affymetrix, Illumina [2573667] (imputed) 7 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST003216 Genome-wide genotyping array 8344 2016-10-07 26582766 Lu X 2015-11-18 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/26582766 Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations. HDL cholesterol 8,344 Han Chinese ancestry individuals 14,739 Han Chinese ancestry individuals Affymetrix, Illumina [2573667] (imputed) 6 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST003215 Genome-wide genotyping array 8344 2016-10-07 26582766 Lu X 2015-11-18 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/26582766 Genetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations. Triglycerides 8,344 Han Chinese ancestry individuals 14,739 Han Chinese ancestry individuals Affymetrix, Illumina [2573667] (imputed) 9 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST003217 Genome-wide genotyping array 8344 2016-09-28 26589003 Federoff M 2015-11-05 Parkinsonism Relat Disord www.ncbi.nlm.nih.gov/pubmed/26589003 Genome-wide estimate of the heritability of Multiple System Atrophy. Multiple system atrophy 907 European ancestry cases, 3,866 European ancestry controls NA NR [11318628] (imputed) 0 multiple system atrophy http://www.ebi.ac.uk/efo/EFO_1001050 GCST003179 Genome-wide genotyping array 4773 2016-04-12 26629533 Meng W 2015-08-04 EBioMedicine www.ncbi.nlm.nih.gov/pubmed/26629533 A Genome-wide Association Study Provides Evidence of Sex-specific Involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) With Diabetic Neuropathic Pain. Neuropathic pain in type 2 diabetes 470 European ancestry male cases, 491 European ancestry female cases, 2,021 European ancestry male controls, 1,239 European ancestry female controls NA Affymetrix, Illumina [6906962] (imputed) 3 neuropathic pain http://www.ebi.ac.uk/efo/EFO_0005762 GCST003063 Genome-wide genotyping array 4221 2016-11-29 27023175 Stringer S 2016-03-29 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/27023175 Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium. Cannabis use 32,330 European ancestry individuals 2,660 African American individuals, 2,967 European ancestry individuals Affymetrix, Illumina [6444471] (imputed) 6 Cannabis use http://www.ebi.ac.uk/efo/EFO_0007585 GCST003382 Genome-wide genotyping array 32330 2016-11-14 26818729 Weinsheimer S 2016-01-27 J Neurol Neurosurg Psychiatry www.ncbi.nlm.nih.gov/pubmed/26818729 Genome-wide association study of sporadic brain arteriovenous malformations. Brain arteriovenous malformations (sporadic) 515 European ancestry cases, 1191 European ancestry controls 608 European ancestry cases, 744 European ancestry controls Affymetrix [4300568] (imputed) 0 Cerebral arteriovenous malformation http://www.orpha.net/ORDO/Orphanet_46724 GCST003318 Genome-wide genotyping array 1706 2016-11-24 26752167 Taylor JY 2016-01-11 Sci Rep www.ncbi.nlm.nih.gov/pubmed/26752167 A Genome-wide study of blood pressure in African Americans accounting for gene-smoking interaction. Systolic blood pressure (cigarette smoking interaction) 1,083 African American individuals 1,427 African American individuals Affymetrix [761050] 8 systolic blood pressure, smoking behaviour measurement http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0005671 GCST003365 Genome-wide genotyping array 1083 2016-11-24 26752167 Taylor JY 2016-01-11 Sci Rep www.ncbi.nlm.nih.gov/pubmed/26752167 A Genome-wide study of blood pressure in African Americans accounting for gene-smoking interaction. Diastolic blood pressure (cigarette smoking interaction) 1,083 African American individuals 1,427 African American individuals Affymetrix [761050] 0 diastolic blood pressure, smoking behaviour measurement http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0005671 GCST003366 Genome-wide genotyping array 1083 2016-11-17 26776603 Honne K 2016-01-18 Arthritis Res Ther www.ncbi.nlm.nih.gov/pubmed/26776603 A longitudinal genome-wide association study of anti-tumor necrosis factor response among Japanese patients with rheumatoid arthritis. Response to anti-TNF therapy in rheumatoid arthritis 31 Japanese ancestry mild cases, 282 Japanese ancestry moderate cases, 131 Japanese ancestry severe cases NA Illumina [4253138] (imputed) 12 response to TNF antagonist http://www.ebi.ac.uk/efo/EFO_0004653 GCST003329 Genome-wide genotyping array 444 2016-11-17 26829030 Asgari MM 2016-01-29 J Invest Dermatol www.ncbi.nlm.nih.gov/pubmed/26829030 Identification of Susceptibility Loci for Cutaneous Squamous Cell Carcinoma. Squamous cell carcinoma 6,891 European ancestry cases, 54,566 European ancestry controls 810 European ancestry cases, 5,600 European ancestry controls Affymetrix [9610468] (imputed) 12 squamous cell carcinoma http://www.ebi.ac.uk/efo/EFO_0000707 GCST003327 Genome-wide genotyping array 61457 2016-12-01 26831199 Pattaro C 2016-01-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26831199 Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Glomerular filtration rate in non diabetics (creatinine) 118,448 European ancestry individuals 36,433 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 37 creatinine measurement, glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208 GCST003401 Genome-wide genotyping array 118448 2016-11-25 26831199 Pattaro C 2016-01-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26831199 Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Glomerular filtration rate in diabetics (creatinine) 11,522 European ancestry individuals 4,955 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 1 creatinine measurement, glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208 GCST003373 Genome-wide genotyping array 11522 2016-11-25 26831199 Pattaro C 2016-01-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26831199 Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Glomerular filtration rate (cystatin C) 32,834 European ancestry individuals 14,930 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 1 glomerular filtration rate, cystatin C measurement http://www.ebi.ac.uk/efo/EFO_0005208, http://www.ebi.ac.uk/efo/EFO_0004617 GCST003375 Genome-wide genotyping array 32834 2016-11-25 26831199 Pattaro C 2016-01-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26831199 Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Chronic kidney disease 12,385 European ancestry cases, 104,780 European ancestry controls 33,972 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 10 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST003374 Genome-wide genotyping array 117165 2016-11-25 26831199 Pattaro C 2016-01-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26831199 Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Glomerular filtration rate (creatinine) 133,413 European ancestry individuals 42,166 European ancestry individuals, up to 16,471 African ancestry individuals, up to 42,296 Asian ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 63 creatinine measurement, glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208 GCST003372 Genome-wide genotyping array 133413 2016-11-25 26831199 Pattaro C 2016-01-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26831199 Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Glomerular filtration rate (creatinine) 133,413 European ancestry individuals, 16,840 African ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 0 creatinine measurement, glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208 GCST003371 Genome-wide genotyping array 150253 2016-11-10 26780889 Below JE 2016-01-19 Sci Rep www.ncbi.nlm.nih.gov/pubmed/26780889 Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs. Cholesterol, total 4,383 Mexican ancestry individuals 7,876 Latin American/Hispanic individuals, European ancestry individuals (Global Lipids Genetics Consortium et al, 2013) Affymetrix [at least 370268] (imputed) 6 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST003302 Genome-wide genotyping array 4383 2016-11-10 26780889 Below JE 2016-01-19 Sci Rep www.ncbi.nlm.nih.gov/pubmed/26780889 Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs. LDL cholesterol 4,383 Mexican ancestry individuals 7,876 Latin American/Hispanic individuals, European ancestry individuals (Global Lipids Genetics Consortium et al, 2013) Affymetrix [at least 370268] (imputed) 4 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST003303 Genome-wide genotyping array 4383 2016-11-10 26780889 Below JE 2016-01-19 Sci Rep www.ncbi.nlm.nih.gov/pubmed/26780889 Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs. Triglycerides 4,383 Mexican ancestry individuals 7,876 Latin American/Hispanic individuals, European ancestry individuals (Global Lipids Genetics Consortium et al, 2013) Affymetrix [at least 370268] (imputed) 5 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST003301 Genome-wide genotyping array 4383 2016-11-10 26780889 Below JE 2016-01-19 Sci Rep www.ncbi.nlm.nih.gov/pubmed/26780889 Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs. HDL cholesterol 4,383 Mexican ancestry individuals 7,876 Latin American/Hispanic individuals, European ancestry individuals (Global Lipids Genetics Consortium et al, 2013) Affymetrix [at least 370268] (imputed) 7 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST003304 Genome-wide genotyping array 4383 2016-11-18 26785701 Wen W 2016-01-20 Sci Rep www.ncbi.nlm.nih.gov/pubmed/26785701 Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference. Waist circumference up to 44,609 East Asian individuals up to 25,553 East Asian individuals, up to 230,044 individuals Affymetrix, Illumina [at least 1850000] (imputed) 8 waist circumference http://www.ebi.ac.uk/efo/EFO_0004342 GCST003335 Genome-wide genotyping array 44609 2016-11-18 26785701 Wen W 2016-01-20 Sci Rep www.ncbi.nlm.nih.gov/pubmed/26785701 Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference. Waist-to-hip ratio adjusted for body mass index up to 39,869 East Asian individuals up to 20,137 East Asian individuals, up to 209,947 individuals Affymetrix, Illumina [at least 1850000] (imputed) 10 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST003338 Genome-wide genotyping array 39869 2016-11-18 26785701 Wen W 2016-01-20 Sci Rep www.ncbi.nlm.nih.gov/pubmed/26785701 Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference. Waist circumference adjusted for body mass index up to 44,609 East Asian individuals up to 24,146 East Asian individuals, up to 229,290 individuals Affymetrix, Illumina [at least 1850000] (imputed) 12 BMI-adjusted waist circumference http://www.ebi.ac.uk/efo/EFO_0007789 GCST003336 Genome-wide genotyping array 44609 2016-11-18 26785701 Wen W 2016-01-20 Sci Rep www.ncbi.nlm.nih.gov/pubmed/26785701 Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference. Waist-hip ratio up to 39,869 East Asian individuals up to 25,553 East Asian individuals, up to 212,173 individuals Affymetrix, Illumina [at least 1850000] (imputed) 0 waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0004343 GCST003337 Genome-wide genotyping array 39869 2016-12-14 26824906 Rankinen T 2016-01-29 PLoS One www.ncbi.nlm.nih.gov/pubmed/26824906 No Evidence of a Common DNA Variant Profile Specific to World Class Endurance Athletes. World class endurance athleticism 60 Japanese ancestry world-class cases, 116 Japanese ancestry controls at least 140 Sub-Saharan African ancestry cases, at least 275 Sub-Saharan African ancestry controls, at least 606 European ancestry cases, at least 978 European ancestry controls, at least 688 Japanese ancestry controls, 78 cases, 101 controls. Illumina [541179] 3 athletic endurance measurement http://www.ebi.ac.uk/efo/EFO_0007818 GCST003458 Genome-wide genotyping array 176 2016-12-14 26824906 Rankinen T 2016-01-29 PLoS One www.ncbi.nlm.nih.gov/pubmed/26824906 No Evidence of a Common DNA Variant Profile Specific to World Class Endurance Athletes. Endurance athleticism 60 Japanese ancestry world-class cases, 116 Japanese ancestry controls at least 343 Sub-Saharan African ancestry cases, at least 275 Sub-Saharan African ancestry controls, at least 837 European ancestry cases, at least 978 European ancestry controls, at least 137 Japanese ancestry cases, at least 688 Japanese ancestry controls, 78 cases, 101 controls. Illumina [541179] 0 athletic endurance measurement http://www.ebi.ac.uk/efo/EFO_0007818 GCST003459 Genome-wide genotyping array 176 2016-12-08 26833246 Lu Y 2016-02-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26833246 New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. Body fat percentage Up to 31,457 European ancestry men, up to 35,030 European ancestry women, up to 8,259 Indian Asian ancestry men, up to 1,030 Indian Asian ancestry women, 973 Korean ancestry men, 1,360 Korean ancestry women, 154 African American men, 262 African American women Up to 12,480 European ancestry men, up to 10,055 European ancestry women, 315 Jamaican ancestry men, 774 Jamaican ancestry women Affymetrix, Illumina, Perlegen [at least 1958375] (imputed) 47 body fat percentage http://www.ebi.ac.uk/efo/EFO_0007800 GCST003435 Genome-wide genotyping array 78525 2016-12-08 26835600 Hu Y 2016-02-02 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26835600 GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person. Morning vs. evening chronotype 38,937 European ancestry morning chronotype individuals, 50,346 European ancestry evening chronotype individuals NA Illumina [7427422] (imputed) 77 circadian rhythm http://www.ebi.ac.uk/efo/EFO_0004354 GCST003429 Genome-wide genotyping array 89283 2016-12-08 26835600 Hu Y 2016-02-02 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26835600 GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person. Chronotype 38,937 European ancestry morning individuals, 50,346 European ancestry evening individuals, at least 32,842 European ancestry neutral individuals NA Illumina [7427422] (imputed) 2 circadian rhythm http://www.ebi.ac.uk/efo/EFO_0004354 GCST003428 Genome-wide genotyping array 122125 2015-11-03 25616667 Goris A 2015-01-22 Brain www.ncbi.nlm.nih.gov/pubmed/25616667 Genetic variants are major determinants of CSF antibody levels in multiple sclerosis. Oligoclonal band status in multiple sclerosis 2,232 European ancestry OCB positive individuals, 275 European ancestry OCB negative individuals, 439 OCB positive individuals, 80 OCB negative individuals 3,026 OCB positive individuals, 452 OCB negative individuals NR [485522] 3 oligoclonal band measurement http://www.ebi.ac.uk/efo/EFO_0005206 GCST002758 Genome-wide genotyping array 3026 2015-11-03 25616667 Goris A 2015-01-22 Brain www.ncbi.nlm.nih.gov/pubmed/25616667 Genetic variants are major determinants of CSF antibody levels in multiple sclerosis. Immunoglobulin G index levels in multiple sclerosis 773 European ancestry Individuals, 165 Individuals 2,072 Individuals NR [485236] 3 IgG index http://www.ebi.ac.uk/efo/EFO_0006929 GCST002757 Genome-wide genotyping array 938 2015-11-06 25628336 Hromatka BS 2015-01-26 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/25628336 Genetic variants associated with motion sickness point to roles for inner ear development, neurological processes and glucose homeostasis. Motion sickness 80,494 European ancestry individuals NA Illumina [7428049] (imputed) 35 motion sickness http://www.ebi.ac.uk/efo/EFO_0006928 GCST002759 Genome-wide genotyping array 80494 2015-11-07 25672891 Shimizu S 2015-02-11 J Dent Res www.ncbi.nlm.nih.gov/pubmed/25672891 A genome-wide association study of periodontitis in a Japanese population. Periodontitis 1,593 Japanese ancestry cases, 7,980 Japanese ancestry controls 1,167 Japanese ancestry cases, 7,178 Japanese ancestry controls Illumina [597434] 2 periodontitis http://www.ebi.ac.uk/efo/EFO_0000649 GCST002781 Genome-wide genotyping array 9573 2015-05-18 25642632 Liu H 2015-02-02 Nat Genet www.ncbi.nlm.nih.gov/pubmed/25642632 Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy. Leprosy 1,548 Chinese ancestry cases, 2,150 Chinese ancestry controls, 4,362 Chinese ancestry controls with immune-related diseases 6,765 Chinese ancestry cases, 9,505 Chinese ancestry controls Illumina [4577171] (imputed) 22 leprosy http://www.ebi.ac.uk/efo/EFO_0001054 GCST002772 Genome-wide genotyping array 8060 2015-12-18 25637523 Springelkamp H 2015-01-30 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/25637523 ARHGEF12 influences the risk of glaucoma by increasing intraocular pressure. Intraocular pressure 8,015 individuals 7,471 individuals Illumina [NR] (imputed) 48 intraocular pressure measurement http://www.ebi.ac.uk/efo/EFO_0004695 GCST002767 Genome-wide genotyping array 8015 2016-11-16 26732429 Wang Z 2016-01-04 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26732429 Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women. Lung cancer 6,877 East Asian ancestry never smoker cases, 6,277 East Asian ancestry never smoker controls 5,878 East Asian ancestry never smoker cases, 7,046 East Asian ancestry never smoker controls Affymetrix, Illumina [7564751] (imputed) 6 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST003325 Genome-wide genotyping array 13154 2016-11-16 26732429 Wang Z 2016-01-04 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26732429 Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women. Adenocarcinoma Up to 5,744 Chinese ancestry cases, up to 4,817 Chinese ancestry controls, up to 1,133 Japanese ancestry cases, up to 1,460 Japanese ancestry controls Up to 4,647 Chinese ancestry cases, up to 4,099 Chinese ancestry controls, up to 1,231 Japanese ancestry cases, up to 2,947 Japanese ancestry controls Affymetrix, Illumina [7564751] (imputed) 5 lung adenocarcinoma http://www.ebi.ac.uk/efo/EFO_0000571 GCST003326 Genome-wide genotyping array 13154 2016-01-30 25823687 Cao S 2015-03-31 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/25823687 Genome-wide association study of myelosuppression in non-small-cell lung cancer patients with platinum-based chemotherapy. Platinum-induced myelosuppression in non-small cell lung cancer 328 Han Chinese ancestry cases 876 Han Chinese ancestry cases Affymetrix [588732] 1 myelosuppression, response to platinum based chemotherapy http://www.ebi.ac.uk/efo/EFO_0007053, http://www.ebi.ac.uk/efo/EFO_0004647 GCST002833 Genome-wide genotyping array 328 2016-12-08 26830138 Herold C 2016-02-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/26830138 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3. Alzheimer disease and age of onset 2,478 European ancestry cases, 979 ancestry controls both from the same 1,070 families NA Affymetrix [up to 15107142] (imputed) 203 Alzheimer's disease, age at onset http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0004847 GCST003427 Genome-wide genotyping array 4527 2017-02-24 26969751 Parmar PG 2016-03-11 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/26969751 International Genome-Wide Association Study Consortium Identifies Novel Loci Associated With Blood Pressure in Children and Adolescents. Diastolic blood pressure 5,008 European ancestry prepubescent females, 5,082 European ancestry prepubescent males, 4,238 European ancestry pubescent females, 4,185 European ancestry pubescent males, 2,680 European ancestry post-pubescent females, 2,496 European ancestry post-pubescent males NA Affymetrix, Illumina, Perlegen [NR] (imputed) 12 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST003671 Genome-wide genotyping array 23689 2017-02-24 26969751 Parmar PG 2016-03-11 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/26969751 International Genome-Wide Association Study Consortium Identifies Novel Loci Associated With Blood Pressure in Children and Adolescents. Systolic blood pressure 5,008 European ancestry prepubescent females, 5,082 European ancestry prepubescent males, 4,238 European ancestry pubescent females, 4,185 European ancestry pubescent males, 2,680 European ancestry post-pubescent females, 2,496 European ancestry post-pubescent males NA Affymetrix, Illumina, Perlegen [NR] (imputed) 16 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST003670 Genome-wide genotyping array 23689 2016-11-30 26733130 Styrkarsdottir U 2016-01-06 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26733130 Sequence variants in the PTCH1 gene associate with spine bone mineral density and osteoporotic fractures. Bone mineral density (spine) up to 20,132 European ancestry individuals 10,092 European and East Asian ancestry individuals Illumina [19689642] (imputed) 7 spine bone mineral density http://www.ebi.ac.uk/efo/EFO_0007701 GCST003388 Genome-wide genotyping array 20132 2016-11-30 26733130 Styrkarsdottir U 2016-01-06 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26733130 Sequence variants in the PTCH1 gene associate with spine bone mineral density and osteoporotic fractures. Bone mineral density (hip) up to 20,162 European ancestry individuals 10,037 European and East Asian ancestry individuals Illumina [19689642] (imputed) 7 hip bone mineral density http://www.ebi.ac.uk/efo/EFO_0007702 GCST003389 Genome-wide genotyping array 20162 2016-02-05 25898920 Korostishevsky M 2015-04-22 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/25898920 Genomics and metabolomics of muscular mass in a community-based sample of UK females. Blood metabolite levels 3,953 European ancestry individuals NA Illumina [2300000] 4 urate measurement, mannose measurement, blood metabolite measurement, X12063 measurement http://www.ebi.ac.uk/efo/EFO_0004531, http://www.ebi.ac.uk/efo/EFO_0006958, http://www.ebi.ac.uk/efo/EFO_0005664, http://www.ebi.ac.uk/efo/EFO_0006957 GCST002872 Genome-wide genotyping array 3953 2015-08-09 25646338 Mozaffarian D 2014-12-10 Am J Clin Nutr www.ncbi.nlm.nih.gov/pubmed/25646338 Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. Trans fatty acid levels 8,013 European ancestry individuals 1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals Affymetrix, Illumina [~ 2500000] (imputed) 131 trans fatty acid measurement http://www.ebi.ac.uk/efo/EFO_0006821 GCST002721 Genome-wide genotyping array 8013 2015-11-03 25607358 Hibar DP 2015-01-21 Nature www.ncbi.nlm.nih.gov/pubmed/25607358 Common genetic variants influence human subcortical brain structures. Subcortical brain region volumes up to 13,171 European ancestry individuals up to 15,130 European ancestry individuals, 545 Japanese ancestry individuals, 736 Mexican American individuals Affymetrix, Illumina [NR] (imputed) 12 brain volume measurement http://www.ebi.ac.uk/efo/EFO_0006930 GCST002756 Genome-wide genotyping array 13171 2016-01-15 25827505 Swaminathan S 2015-03-14 J Affect Disord www.ncbi.nlm.nih.gov/pubmed/25827505 Characteristics of Bipolar I patients grouped by externalizing disorders. Bipolar disorder 472 non-externalizing cases, 796 externalizing cases 436 non-externalizing European ancestry cases, 801 externalizing European ancestry cases Affymetrix [677171] 4 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST002809 Genome-wide genotyping array 1268 2015-11-12 25826619 Henrion MY 2015-03-31 PLoS One www.ncbi.nlm.nih.gov/pubmed/25826619 Common variation at 1q24.1 (ALDH9A1) is a potential risk factor for renal cancer. Renal cell carcinoma 2,215 Western European ancestry cases, 8,566 Western European ancestry controls 2,844 European ancestry cases, 7,270 European ancestry controls Illumina [up to 12182133] (imputed) 3 renal cell carcinoma http://www.ebi.ac.uk/efo/EFO_0000681 GCST002835 Genome-wide genotyping array 10781 2016-10-14 26626624 Stuart PE 2015-11-28 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/26626624 Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture. Cutaneous psoriasis 1,363 European ancestry cases, 4,934 European ancestry controls up to 2,969 European ancestry cases, up to European ancestry 14,384 controls Illumina [11532644] (imputed) 10 cutaneous psoriasis measurement, psoriasis http://www.ebi.ac.uk/efo/EFO_0007773, http://www.ebi.ac.uk/efo/EFO_0000676 GCST003269 Genome-wide genotyping array 6297 2016-10-14 26626624 Stuart PE 2015-11-28 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/26626624 Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture. Psoriasis vulgaris 4,007 European ancestry cases, 4,934 European ancestry controls up to 9,075 European ancestry cases, up to European ancestry 12,726 controls Illumina [up to 11532644] (imputed) 39 psoriasis vulgaris http://www.ebi.ac.uk/efo/EFO_1001494 GCST003268 Genome-wide genotyping array 8941 2016-10-14 26626624 Stuart PE 2015-11-28 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/26626624 Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture. Psoriatic arthritis 1,946 European ancestry cases, 4,934 European ancestry controls up to 2,883 European ancestry cases, up to 14,179 European ancestry controls Illumina [11532644] (imputed) 14 psoriatic arthritis http://www.ebi.ac.uk/efo/EFO_0003778 GCST003270 Genome-wide genotyping array 6880 2016-10-14 26626624 Stuart PE 2015-11-28 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/26626624 Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture. Psoriatic arthritis vs Cutaneous psoriasis 1,946 European ancestry psoriatic arthritis cases, 1,363 European ancestry cuteneous psoriasis cases up to 3,216 European ancestry psoriatic arthritis cases, up to 2,968 European ancestry cuteneous psoriasis cases Illumina [11532644] (imputed) 0 cutaneous psoriasis measurement, psoriatic arthritis, psoriasis http://www.ebi.ac.uk/efo/EFO_0007773, http://www.ebi.ac.uk/efo/EFO_0003778, http://www.ebi.ac.uk/efo/EFO_0000676 GCST003271 Genome-wide genotyping array 3309 2016-11-25 26833098 Kilpelainen TO 2016-02-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26833098 Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. circulating leptin levels adjusted for BMI up to 14,094 European ancestry men, up to 19,893 European ancestry women up to 9,076 European ancestry men, up to 9,150 European ancestry women Affymetrix, Illumina [~ 2500000] (imputed) 9 BMI-adjusted leptin measurement http://www.ebi.ac.uk/efo/EFO_0007793 GCST003368 Genome-wide genotyping array 33987 2016-11-25 26833098 Kilpelainen TO 2016-02-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26833098 Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. circulating leptin levels 14,586 European ancestry men, 20,706 European ancestry women 8,554 European ancestry men, 8,337 European ancestry women Affymetrix, Illumina [~ 2500000] (imputed) 10 leptin measurement http://www.ebi.ac.uk/efo/EFO_0005000 GCST003367 Genome-wide genotyping array 35292 2016-10-10 26528553 Davenport ER 2015-11-03 PLoS One www.ncbi.nlm.nih.gov/pubmed/26528553 Genome-Wide Association Studies of the Human Gut Microbiota. Gut microbiome composition (summer) 91 Hutterite individuals NA Affymetrix [210924] 35 seasonal gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007753 GCST003221 Genome-wide genotyping array 91 2016-10-10 26528553 Davenport ER 2015-11-03 PLoS One www.ncbi.nlm.nih.gov/pubmed/26528553 Genome-Wide Association Studies of the Human Gut Microbiota. Gut microbiome composition (summer and winter) 127 Hutterite individuals NA Affymetrix [212153] 9 seasonal gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007753 GCST003222 Genome-wide genotyping array 127 2016-10-10 26528553 Davenport ER 2015-11-03 PLoS One www.ncbi.nlm.nih.gov/pubmed/26528553 Genome-Wide Association Studies of the Human Gut Microbiota. Gut microbiome composition (winter) 93 Hutterite individuals NA Affymetrix [211319] 33 seasonal gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007753 GCST003223 Genome-wide genotyping array 93 2016-09-12 26420894 Wuttke M 2015-09-28 Nephrol Dial Transplant www.ncbi.nlm.nih.gov/pubmed/26420894 Genetic loci associated with renal function measures and chronic kidney disease in children: the Pediatric Investigation for Genetic Factors Linked with Renal Progression Consortium. Proteinuria in chronic kidney disease up to 744 European ancestry child cases, up to 397 Turkish ancestry child cases NA Illumina [~ 8300000] (imputed) 4 Proteinuria http://purl.obolibrary.org/obo/HP_0000093 GCST003142 Genome-wide genotyping array 1141 2016-09-12 26420894 Wuttke M 2015-09-28 Nephrol Dial Transplant www.ncbi.nlm.nih.gov/pubmed/26420894 Genetic loci associated with renal function measures and chronic kidney disease in children: the Pediatric Investigation for Genetic Factors Linked with Renal Progression Consortium. Chronic kidney disease 658 European ancestry child cases, 1,347 European ancestry child controls NA Illumina [~ 8300000] (imputed) 5 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST003140 Genome-wide genotyping array 2005 2016-09-12 26420894 Wuttke M 2015-09-28 Nephrol Dial Transplant www.ncbi.nlm.nih.gov/pubmed/26420894 Genetic loci associated with renal function measures and chronic kidney disease in children: the Pediatric Investigation for Genetic Factors Linked with Renal Progression Consortium. Proteinuria and chronic kidney disease 294 European ancestry child cases, 1,347 European ancestry child controls NA Illumina [~ 10500000] (imputed) 9 chronic kidney disease, Proteinuria http://www.ebi.ac.uk/efo/EFO_0003884, http://purl.obolibrary.org/obo/HP_0000093 GCST003141 Genome-wide genotyping array 1641 2016-09-12 26420894 Wuttke M 2015-09-28 Nephrol Dial Transplant www.ncbi.nlm.nih.gov/pubmed/26420894 Genetic loci associated with renal function measures and chronic kidney disease in children: the Pediatric Investigation for Genetic Factors Linked with Renal Progression Consortium. Glomerular filtration rate in chronic kidney disease up to 744 Central European ancestry child cases, up to 397 Turkish ancestry child cases NA Illumina [~ 8300000] (imputed) 22 glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0005208 GCST003139 Genome-wide genotyping array 1141 2016-02-11 25986216 Toyoda H 2015-05-15 Brain Behav Immun www.ncbi.nlm.nih.gov/pubmed/25986216 A polymorphism in CCR1/CCR3 is associated with narcolepsy. Narcolepsy with cataplexy 409 Japanese ancestry cases, 1,562 Japanese ancestry controls 240 Japanese ancestry cases, 869 Japanese ancestry controls Affymetrix [525196] 4 narcolepsy with cataplexy http://www.ebi.ac.uk/efo/EFO_0000614 GCST002912 Genome-wide genotyping array 1971 2016-02-12 25956309 Palomba G 2015-05-10 BMC Cancer www.ncbi.nlm.nih.gov/pubmed/25956309 Genome-wide association study of susceptibility loci for breast cancer in Sardinian population. Breast cancer 1,367 Sardinian cases, 1,658 Sardinian controls 201 Sardinian cases, 1,467 Sardinian controls, 61,485 European ancestry cases, 60,860 European ancestry controls Affymetrix [2067645] (imputed) 2 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST002895 Genome-wide genotyping array 3025 2016-02-12 25950743 Uttayamakul S 2015-06-15 AIDS Res Hum Retroviruses www.ncbi.nlm.nih.gov/pubmed/25950743 Genome-Wide Association Study of HIV-Related Lipoatrophy in Thai Patients: Association of a DLGAP1 Polymorphism with Fat Loss. Response to stavudine in HIV (lipoatrophy) 49 Thai ancestry cases, 92 Thai ancestry controls 95 Thai ancestry cases, 95 Thai ancestry controls Illumina [458071] 0 response to stavudine, Lipoatrophy http://www.ebi.ac.uk/efo/EFO_0006998, http://purl.obolibrary.org/obo/HP_0100578 GCST002968 Genome-wide genotyping array 141 2016-02-11 25988933 Almli LM 2015-05-18 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/25988933 A genome-wide identified risk variant for PTSD is a methylation quantitative trait locus and confers decreased cortical activation to fearful faces. Post-traumatic stress disorder 32 Hispanic ancestry cases, 16 Black cases, 14 European ancestry cases, 1 other ancestry case, 25 Hispanic ancestry controls, 6 Asian ancestry controls, 19 Black controls, 31 European ancestry controls, 3 other ancestry controls 2,868 African American ancestry individuals Illumina [557423] 0 post-traumatic stress disorder http://www.ebi.ac.uk/efo/EFO_0001358 GCST002914 Genome-wide genotyping array 147 2016-07-08 25961943 Surakka I 2015-05-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/25961943 The impact of low-frequency and rare variants on lipid levels. HDL cholesterol up to 62,166 European ancestry individuals NA Affymetrix, Illumina, Perlegen [up to 9657952] (imputed) 42 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST002899 Genome-wide genotyping array 62166 2016-07-08 25961943 Surakka I 2015-05-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/25961943 The impact of low-frequency and rare variants on lipid levels. Triglycerides up to 62,166 European ancestry individuals NA Affymetrix, Illumina, Perlegen [up to 9657952] (imputed) 35 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST002897 Genome-wide genotyping array 62166 2016-07-08 25961943 Surakka I 2015-05-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/25961943 The impact of low-frequency and rare variants on lipid levels. LDL cholesterol up 62,166 European ancestry individuals NA Affymetrix, Illumina, Perlegen [up to 9657952] (imputed) 43 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST002898 Genome-wide genotyping array 62166 2016-07-08 25961943 Surakka I 2015-05-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/25961943 The impact of low-frequency and rare variants on lipid levels. Cholesterol, total up to 62,166 European ancestry individuals NA Affymetrix, Illumina, Perlegen [up to 9657952] (imputed) 47 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST002896 Genome-wide genotyping array 62166 2016-02-24 25963547 Wilson CL 2015-05-11 Cancer www.ncbi.nlm.nih.gov/pubmed/25963547 Genetic and clinical factors associated with obesity among adult survivors of childhood cancer: A report from the St. Jude Lifetime Cohort. Obesity in adult survivors of childhood cancer exposed to cranial radiation 365 obese individuals, 411 non-obese individuals NA Affymetrix [NR] (imputed) 4 response to radiation, obesity http://purl.obolibrary.org/obo/GO_0009314, http://www.ebi.ac.uk/efo/EFO_0001073 GCST002900 Genome-wide genotyping array 776 2016-02-24 25963547 Wilson CL 2015-05-11 Cancer www.ncbi.nlm.nih.gov/pubmed/25963547 Genetic and clinical factors associated with obesity among adult survivors of childhood cancer: A report from the St. Jude Lifetime Cohort. Obesity in adult survivors of childhood cancer not exposed to cranial radiation 359 obese individuals, 861 non-obese individuals NA Affymetrix [NR] (imputed) 1 obesity http://www.ebi.ac.uk/efo/EFO_0001073 GCST002904 Genome-wide genotyping array 1220 2016-04-12 25948407 Kertai MD 2015-05-06 BMJ Open www.ncbi.nlm.nih.gov/pubmed/25948407 Genome-wide association study of perioperative myocardial infarction after coronary artery bypass surgery. Perioperative myocardial infarction in coronary artery bypass surgery 112 cases, 1,321 controls 113 European ancestry cases, 509 European ancestry controls Illumina [534390] 15 myocardial infarction http://www.ebi.ac.uk/efo/EFO_0000612 GCST002892 Genome-wide genotyping array 1433 2015-11-21 25972035 Vinayagamoorthy N 2015-05-14 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/25972035 Association of common variants in the calcium-sensing receptor gene with serum calcium levels in East Asians. Calcium levels 4,558 Korean ancestry individuals 4,093 Korean ancestry individuals Affymetrix [1219546] (imputed) 12 calcium measurement http://www.ebi.ac.uk/efo/EFO_0004838 GCST002911 Genome-wide genotyping array 4558 2016-02-12 26014426 Ruth KS 2015-05-27 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/26014426 Genome-wide association study with 1000 genomes imputation identifies signals for nine sex hormone-related phenotypes. Sex hormone levels up to 2913 European ancestry individuals NA Illumina [7879351] (imputed) 15 hormone measurement http://www.ebi.ac.uk/efo/EFO_0004730 GCST002925 Genome-wide genotyping array 2913 2016-06-01 26169365 Huang KC 2015-07-14 BMC Complement Altern Med www.ncbi.nlm.nih.gov/pubmed/26169365 Susceptible gene of stasis-stagnation constitution from genome-wide association study related to cardiovascular disturbance and possible regulated traditional Chinese medicine. Yu-Zhi constitution type in type 2 diabetes 539 non-aboriginal Taiwanese ancestry low Yu-Zhi score individuals, 408 non-aboriginal Taiwanese ancestry high Yu-Zhi score individuals NA Illumina [508761] 11 Yu-Zhi constitution type http://www.ebi.ac.uk/efo/EFO_0007638 GCST003026 Genome-wide genotyping array 947 2016-06-10 26198393 Ziv E 2015-07-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26198393 Genome-wide association study identifies variants at 16p13 associated with survival in multiple myeloma patients. Multiple myeloma (survival) 469 European ancestry cases, 25 African American cases, 27 Latino cases, 24 cases 1090 European ancestry cases Affymetrix, Illumina [6026834] (imputed) 1 overall survival, multiple myeloma http://www.ebi.ac.uk/efo/EFO_0000638, http://www.ebi.ac.uk/efo/EFO_0001378 GCST003051 Genome-wide genotyping array 545 2016-04-26 26039976 Wei Z 2015-06-17 Sci Rep www.ncbi.nlm.nih.gov/pubmed/26039976 Genome-Wide Association Studies of HIV-1 Host Control in Ethnically Diverse Chinese Populations. HIV-1 viral setpoint 326 Han Chinese ancestry cases, 58 Dai Chinese ancestry cases, 40 Jingpo Chinese ancestry cases, 83 Uygur Chinese ancestry cases, 11 Hui Chinese ancestry cases, 20 East Asian cases NA Illumina [up to 528294] 9 HIV viral set point measurement http://www.ebi.ac.uk/efo/EFO_0006319 GCST002976 Genome-wide genotyping array 538 2016-09-12 26249676 Wolthusen RP 2015-08-07 World J Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/26249676 Genetic underpinnings of left superior temporal gyrus thickness in patients with schizophrenia. Left superior temporal gyrus thickness (schizophrenia interaction) 113 schizophrenia cases, 126 controls NA Illumina [1067955] (imputed) 6 schizophrenia, left superior temporal gyrus thickness measurement http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0007739 GCST003069 Genome-wide genotyping array 239 2016-07-15 26190474 Dai Y 2015-07-20 Sci Rep www.ncbi.nlm.nih.gov/pubmed/26190474 Performance of genetic risk factors in prediction of trichloroethylene induced hypersensitivity syndrome. Trichloroethylene-induced hypersensitivity syndrome 98 Han Chinese ancestry cases, 98 Han Chinese ancestry trichloroethylene-tolerant controls Up to 74 Han Chinese ancestry cases, up to 1,661 Han Chinese ancestry trichloroethylene-tolerant controls Illumina [1392644] 3 trichloroethylene-induced hypersensitivity http://www.ebi.ac.uk/efo/EFO_0007685 GCST003046 Genome-wide genotyping array 196 2016-09-27 26580837 Chen CJ 2015-11-18 Biomark Med www.ncbi.nlm.nih.gov/pubmed/26580837 A genome-wide association study on amyotrophic lateral sclerosis in the Taiwanese Han population. Amyotrophic lateral sclerosis 94 Taiwanese Han ancestry cases, 376 Taiwanese Han ancestry controls NA Affymetrix [633420] 6 amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0000253 GCST003175 Genome-wide genotyping array 470 2016-08-17 26265036 Parra EJ 2015-08-12 Pharmacogenomics www.ncbi.nlm.nih.gov/pubmed/26265036 Genome-wide association study of warfarin maintenance dose in a Brazilian sample. Warfarin maintenance dose 180 Brazilian ancestry low dose individuals, 187 Brazilian ancestry high dose individuals 798 European ancestry individuals, 1611 Japanese ancestry individuals, 191 African American individuals Affymetrix [> 650000] (imputed) 16 response to anticoagulant http://purl.obolibrary.org/obo/GO_0061476 GCST003085 Genome-wide genotyping array 367 2016-07-27 26237429 Aminkeng F 2015-08-03 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26237429 A coding variant in RARG confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer. Anthracycline-induced cardiotoxicity in childhood cancer 32 European ancestry cases with cardiotoxicity, 248 European ancestry cases without cardiotoxicity 22 European ancestry cases with cardiotoxicity, 74 European ancestry cases without cardiotoxicity, 2 African cases with cardiotoxicity, 9 African cases without cardiotoxicity, 5 Hispanic cases with cardiotoxicity, 18 Hispanic cases without cardiotoxicity, 8 East Asian cases with cardiotoxicity, 23 East Asian cases without cardiotoxicity, 4 Aboriginal Canadian cases with cardiotoxicity, 11 Aboriginal Canadian cases without cardiotoxicity Illumina [657694] 2 cardiotoxicity, response to anthracycline-based chemotherapy http://www.ebi.ac.uk/efo/EFO_1001482, http://www.ebi.ac.uk/efo/EFO_0005257 GCST003062 Genome-wide genotyping array 280 2016-10-06 26566055 Mieda T 2015-11-13 Pharmacogenomics www.ncbi.nlm.nih.gov/pubmed/26566055 Genome-wide association study identifies candidate loci associated with postoperative fentanyl requirements after laparoscopic-assisted colectomy. Fentanyl consumption in laparoscopic-assisted colectomy (first 24 hours) 116 Japanese ancestry individuals 234 Japanese ancestry individuals Illumina [921239] 1 post-operative fentanyl consumption measurement http://www.ebi.ac.uk/efo/EFO_0007770 GCST003200 Genome-wide genotyping array 116 2016-06-02 26237428 Law MH 2015-08-03 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26237428 Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma. Cutaneous malignant melanoma 12,874 European ancestry cases, 23,203 European ancestry controls 785 European ancestry cases, 791 European ancestry controls, 2,331 cases, 2,415 controls Affymetrix, Illumina [at least 1569314] (imputed) 16 cutaneous melanoma http://www.ebi.ac.uk/efo/EFO_0000389 GCST003061 Genome-wide genotyping array 36077 2016-07-20 26256467 Wojczynski MK 2015-07-03 Metabolism www.ncbi.nlm.nih.gov/pubmed/26256467 Genome-wide association study of triglyceride response to a high-fat meal among participants of the NHLBI Genetics of Lipid Lowering Drugs and Diet Network (GOLDN). Postprandial triglyceride response to high fat diet meal 872 European ancestry individuals 843 Old Order Amish individuals Affymetrix, Illumina [~ 2500000] (imputed) 9 response to high fat food intake, triglyceride change measurement http://www.ebi.ac.uk/efo/EFO_0007684, http://www.ebi.ac.uk/efo/EFO_0007681 GCST003014 Genome-wide genotyping array 872 2016-10-14 26390057 Kato N 2015-09-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26390057 Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Systolic blood pressure 31,516 East Asian ancestry individuals, 35,352 European ancestry individuals, 33,126 South Asian ancestry individuals 87,205 individuals, 48,268 East Asian ancestry individuals, 68,456 European ancestry individuals and 16,328 South Asian ancestry individuals Affymetrix, Illumina, Perlegen [2127883] (imputed) 17 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST003272 Genome-wide genotyping array 99994 2016-10-14 26390057 Kato N 2015-09-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26390057 Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Hypertension 31,516 East Asian ancestry individuals, 35,352 European ancestry individuals, 33,126 South Asian ancestry individuals 87,205 individuals, 48,268 East Asian ancestry individuals, 68,456 European ancestry individuals and 16,328 South Asian ancestry individuals Affymetrix, Illumina, Perlegen [~ 2100000] (imputed) 0 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST003276 Genome-wide genotyping array 99994 2016-10-14 26390057 Kato N 2015-09-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26390057 Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Pulse pressure 31,516 East Asian ancestry individuals, 35,352 European ancestry individuals, 33,126 South Asian ancestry individuals 87,205 individuals, 48,268 East Asian ancestry individuals, 68,456 European ancestry individuals and 16,328 South Asian ancestry individuals Affymetrix, Illumina, Perlegen [~ 2100000] (imputed) 11 pulse pressure measurement http://www.ebi.ac.uk/efo/EFO_0005763 GCST003274 Genome-wide genotyping array 99994 2016-10-14 26390057 Kato N 2015-09-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26390057 Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Mean arterial pressure 31,516 East Asian ancestry individuals, 35,352 European ancestry individuals, 33,126 South Asian ancestry individuals 87,205 individuals, 48,268 East Asian ancestry individuals, 68,456 European ancestry individuals and 16,328 South Asian ancestry individuals Affymetrix, Illumina, Perlegen [~ 2100000] (imputed) 13 mean arterial pressure http://www.ebi.ac.uk/efo/EFO_0006340 GCST003275 Genome-wide genotyping array 99994 2016-10-14 26390057 Kato N 2015-09-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26390057 Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Diastolic blood pressure 31,516 East Asian ancestry individuals, 35,352 European ancestry individuals, 33,126 South Asian ancestry individuals 87,205 individuals, 48,268 East Asian ancestry individuals, 68,456 European ancestry individuals, 16,328 South Asian ancestry individuals Affymetrix, Illumina, Perlegen [~ 2100000] (imputed) 20 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST003273 Genome-wide genotyping array 99994 2017-02-24 26977737 Cade BE 2016-03-15 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/26977737 Genetic Associations with Obstructive Sleep Apnea Traits in Hispanic/Latino Americans. Obstructive sleep apnea trait (apnea hypopnea index) 12,558 Hispanic/Latin American individuals 214 Asian ancestry individuals, 1,183 African American individuals, 5,638 European ancestry individuals Affymetrix, Illumina [NR] (imputed) 12 sleep apnea measurement, obstructive sleep apnea http://www.ebi.ac.uk/efo/EFO_0007817, http://www.ebi.ac.uk/efo/EFO_0003918 GCST003674 Genome-wide genotyping array 12558 2017-02-24 26977737 Cade BE 2016-03-15 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/26977737 Genetic Associations with Obstructive Sleep Apnea Traits in Hispanic/Latino Americans. Obstructive sleep apnea (average oxygen saturation during sleep) 12,557 Hispanic/Latin American ancestry individuals 214 Asian ancestry individuals, 1,183 African American ancestry individuals, 5,638 European ancestry individuals Affymetrix, Illumina [NR] (imputed) 5 sleep apnea measurement, obstructive sleep apnea http://www.ebi.ac.uk/efo/EFO_0007817, http://www.ebi.ac.uk/efo/EFO_0003918 GCST003673 Genome-wide genotyping array 12557 2017-02-24 26977737 Cade BE 2016-03-15 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/26977737 Genetic Associations with Obstructive Sleep Apnea Traits in Hispanic/Latino Americans. Obstructive sleep apnea trait (average respiratory event duration) 10,238 Hispanic/Latin American ancestry individuals 214 Asian ancestry individuals, 1,183 African American ancestry individuals, 5,638 European ancestry individuals Affymetrix, Illumina [NR] (imputed) 14 sleep apnea measurement, obstructive sleep apnea http://www.ebi.ac.uk/efo/EFO_0007817, http://www.ebi.ac.uk/efo/EFO_0003918 GCST003675 Genome-wide genotyping array 10238 2016-12-13 26955885 Lane JM 2016-03-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26955885 Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank. Chronotype 100,420 European ancestry individuals NA Affymetrix [~ 73355677] (imputed) 14 circadian rhythm http://www.ebi.ac.uk/efo/EFO_0004354 GCST003453 Genome-wide genotyping array 100420 2016-12-13 26955885 Lane JM 2016-03-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26955885 Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank. Morning vs. evening chronotype 8,724 European ancestry evening chronotype individuals, 26,948 European ancestry morning chronotype individuals NA Affymetrix [73355677] (imputed) 10 circadian rhythm http://www.ebi.ac.uk/efo/EFO_0004354 GCST003454 Genome-wide genotyping array 35672 2016-12-12 26980576 Kim K 2016-03-15 J Rheumatol www.ncbi.nlm.nih.gov/pubmed/26980576 Response to Intravenous Cyclophosphamide Treatment for Lupus Nephritis Associated with Polymorphisms in the FCGR2B-FCRLA Locus. Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis 93 Korean ancestry responder cases, 16 Korean ancestry non-responder cases NA Illumina [491617] 14 response to cyclophosphamide http://purl.obolibrary.org/obo/GO_1902518 GCST003445 Genome-wide genotyping array 109 2016-09-07 26265699 Karol SE 2015-08-11 Blood www.ncbi.nlm.nih.gov/pubmed/26265699 Genetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia. Glucocorticoid-induced osteonecrosis (time dependent analysis) 164 European ancestry osteonecrosis cases, 4 Black osteonecrosis cases, 58 Hispanic osteonecrosis cases, 5 Asian ancestry osteonecrosis cases, 19 other ancestry osteonecrosis cases, 1,111 European ancestry treated controls, 135 Black treated controls, 543 Hispanic treated controls, 43 Asian ancestry treated controls, 203 other ancestry treated controls NA Affymetrix, Illumina [NR] (imputed) 3 response to glucocorticoid, osteonecrosis http://purl.obolibrary.org/obo/GO_0051384, http://www.ebi.ac.uk/efo/EFO_0004259 GCST003083 Genome-wide genotyping array 2285 2016-09-07 26265699 Karol SE 2015-08-11 Blood www.ncbi.nlm.nih.gov/pubmed/26265699 Genetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia. Glucocorticoid-induced osteonecrosis (time independent analysis) 235 osteonecrosis cases, 1,687 treated controls 110 European ancestry osteonecrosis cases, 21 Black osteonecrosis cases, 10 Hispanic osteonecrosis cases, 1 Asian ancestry osteonecrosis case, 8 other ancestry osteonecrosis cases, 366 European ancestry treated controls, 88 Black treated controls, 29 Hispanic treated controls, 5 Asian ancestry treated controls, 32 other ancestry treated controls Affymetrix, Illumina [NR] (imputed) 0 response to glucocorticoid, osteonecrosis http://purl.obolibrary.org/obo/GO_0051384, http://www.ebi.ac.uk/efo/EFO_0004259 GCST003080 Genome-wide genotyping array 1922 2016-09-07 26265699 Karol SE 2015-08-11 Blood www.ncbi.nlm.nih.gov/pubmed/26265699 Genetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia. Glucocorticoid-induced osteonecrosis (age 10 years and older) 230 osteonecrosis cases, 1,238 treated controls NA Affymetrix, Illumina [NR] (imputed) 11 response to glucocorticoid, osteonecrosis http://purl.obolibrary.org/obo/GO_0051384, http://www.ebi.ac.uk/efo/EFO_0004259 GCST003081 Genome-wide genotyping array 1468 2016-09-07 26265699 Karol SE 2015-08-11 Blood www.ncbi.nlm.nih.gov/pubmed/26265699 Genetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia. Glucocorticoid-induced osteonecrosis 274 European ancestry osteonecrosis cases, 25 Black osteonecrosis cases, 68 Hispanic osteonecrosis cases, 6 Asian ancestry osteonecrosis cases, 27 other ancestry osteonecrosis cases, 1,477 European ancestry treated controls, 223 Black treated controls, 572 Hispanic treated controls, 48 Asian ancestry treated controls, 235 other ancestry treated controls NA Affymetrix, Illumina [NR] (imputed) 10 response to glucocorticoid, osteonecrosis http://purl.obolibrary.org/obo/GO_0051384, http://www.ebi.ac.uk/efo/EFO_0004259 GCST003084 Genome-wide genotyping array 2955 2016-04-28 26049409 Hirano A 2015-06-05 Psychiatr Genet www.ncbi.nlm.nih.gov/pubmed/26049409 A genome-wide association study of late-onset Alzheimer's disease in a Japanese population. Alzheimer's disease (late onset) 489 Japanese ancestry APOE-ε4 noncarrier cases, 6,463 Japanese ancestry APOE-ε4 noncarrier controls, 323 Japanese ancestry APOE-ε4 carrier cases, 1,484 Japanese ancestry APOE-ε4 carrier controls, 4 Japanese ancestry cases, 45 Japanese ancestry controls 528 Japanese ancestry APOE-ε4 noncarrier cases, 5,824 Japanese ancestry APOE-ε4 noncarrier controls, 480 Japanese ancestry APOE-ε4 carrier cases, 1,364 Japanese ancestry APOE-ε4 carrier controls, 3 Japanese ancestry cases, 24 Japanese ancestry controls Illumina [561143] 3 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST002954 Genome-wide genotyping array 8824 2016-02-11 25963331 Hatzimanolis A 2015-05-12 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/25963331 Common genetic variation and schizophrenia polygenic risk influence neurocognitive performance in young adulthood. Endophenotypes for schizophrenia in healthy individuals 1,079 European ancestry male cases 1,563 European ancestry male cases Affymetrix [5654592] (imputed) 0 endophenotype http://www.ebi.ac.uk/efo/EFO_0006988 GCST002905 Genome-wide genotyping array 1079 2016-03-24 26007630 Swaminathan B 2015-05-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26007630 Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma. Multiple myeloma 2,194 European ancestry cases, 222,555 European ancestry controls 586 European ancestry cases, 2,111 European ancestry controls Illumina [12100000] (imputed) 8 multiple myeloma http://www.ebi.ac.uk/efo/EFO_0001378 GCST002921 Genome-wide genotyping array 224749 2016-03-24 26007630 Swaminathan B 2015-05-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26007630 Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma. Multiple myeloma and monoclonal gammopathy 2,194 European ancestry multiple myeloma cases, 251 European ancestry monoclonal gammopathy cases, 294,390 European ancestry controls 586 European ancestry multiple myeloma cases, 2,111 European ancestry controls Illumina [12100000] (imputed) 9 multiple myeloma, monoclonal gammopathy http://www.ebi.ac.uk/efo/EFO_0001378, http://www.ebi.ac.uk/efo/EFO_0000203 GCST002922 Genome-wide genotyping array 296835 2016-04-21 26015512 Komatsu M 2015-05-26 Clin Cancer Res www.ncbi.nlm.nih.gov/pubmed/26015512 Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy. Paclitaxel-induced neuropathy 24 Japanese ancestry cases, 121 Japanese ancestry controls NA Illumina [733202] 0 peripheral neuropathy, response to paclitaxel http://www.ebi.ac.uk/efo/EFO_0003100, http://purl.obolibrary.org/obo/GO_1901555 GCST002923 Genome-wide genotyping array 145 2016-04-21 26015512 Komatsu M 2015-05-26 Clin Cancer Res www.ncbi.nlm.nih.gov/pubmed/26015512 Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy. Paclitaxel-induced cytotoxicity 57 Japanese ancestry lymphoblastoid cell lines, 59 Han Chinese ancestry lymphoblastoid cell lines 77 European ancestry lymphoblastoid cell lines, 87 Yoruban ancestry lymphoblastoid cell lines, 83 African ancestry lymphoblastoid cell lines NR [~ 4600000] (imputed) 3 cytotoxicity measurement, response to paclitaxel http://www.ebi.ac.uk/efo/EFO_0006952, http://purl.obolibrary.org/obo/GO_1901555 GCST002924 Genome-wide genotyping array 116 2016-07-14 26053186 Park SL 2015-06-08 PLoS One www.ncbi.nlm.nih.gov/pubmed/26053186 Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer. 3-hydroxypropylmercapturic acid levels in smokers 362 African American current smoker individuals, 329 Native Hawaiian ancestry current smoker individuals, 438 European ancestry current smoker individuals, 449 Latino current smoker individuals, 704 Japanese ancestry current smoker individuals NA Illumina [up to 11892802] (imputed) 246 3-hydroxypropylmercapturic acid measurement http://www.ebi.ac.uk/efo/EFO_0007014 GCST002956 Genome-wide genotyping array 2282 2016-07-13 26053186 Park SL 2015-06-08 PLoS One www.ncbi.nlm.nih.gov/pubmed/26053186 Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer. 3-hydroxy-1-methylpropylmercapturic acid levels in smokers 361 African American current smoker individuals, 329 Native Hawaiian ancestry current smoker individuals, 440 European ancestry current smoker individuals, 452 Latino current smoker individuals, 702 Japanese ancestry current smoker individuals NA Illumina [up to 11892802] (imputed) 240 3-hydroxy-1-methylpropylmercapturic acid measurement http://www.ebi.ac.uk/efo/EFO_0007015 GCST002957 Genome-wide genotyping array 2284 2016-06-16 26184321 Lin BD 2015-07-13 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/26184321 Heritability and Genome-Wide Association Studies for Hair Color in a Dutch Twin Family Based Sample. Blond vs non-blond hair color 2,888 European ancestry blond hair individuals, 4,203 European ancestry non-blond hair individuals NA Affymetrix, Illumina, Perlegen [6473680] (imputed) 6 hair color http://www.ebi.ac.uk/efo/EFO_0003924 GCST003023 Genome-wide genotyping array 7091 2016-06-16 26184321 Lin BD 2015-07-13 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/26184321 Heritability and Genome-Wide Association Studies for Hair Color in a Dutch Twin Family Based Sample. Brown vs. non-brown hair color 3,826 European ancestry brown hair individuals, 3,265 European ancestry non-brown hair individuals NA Affymetrix, Illumina, Perlegen [6473680] (imputed) 8 hair color http://www.ebi.ac.uk/efo/EFO_0003924 GCST003021 Genome-wide genotyping array 7091 2016-06-16 26184321 Lin BD 2015-07-13 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/26184321 Heritability and Genome-Wide Association Studies for Hair Color in a Dutch Twin Family Based Sample. Light vs. dark hair color 3,069 European ancestry light hair individuals, 4,022 European ancestry dark hair individuals NA Affymetrix, Illumina, Perlegen [6473680] (imputed) 8 hair color http://www.ebi.ac.uk/efo/EFO_0003924 GCST003022 Genome-wide genotyping array 7091 2016-06-16 26184321 Lin BD 2015-07-13 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/26184321 Heritability and Genome-Wide Association Studies for Hair Color in a Dutch Twin Family Based Sample. Red vs non-red hair color 181 European ancestry red hair individuals, 6,910 European ancestry non-red hair individuals NA Affymetrix, Illumina, Perlegen [6473680] (imputed) 3 hair color http://www.ebi.ac.uk/efo/EFO_0003924 GCST003020 Genome-wide genotyping array 7091 2016-06-16 26184321 Lin BD 2015-07-13 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/26184321 Heritability and Genome-Wide Association Studies for Hair Color in a Dutch Twin Family Based Sample. Black vs. non-black hair color 196 European ancestry black hair individuals, 6,895 European ancestry non-black hair individuals NA Affymetrix, Illumina, Perlegen [6473680] (imputed) 2 hair color http://www.ebi.ac.uk/efo/EFO_0003924 GCST003019 Genome-wide genotyping array 7091 2016-07-01 26227905 Hu Y 2015-07-31 Mol Neurobiol www.ncbi.nlm.nih.gov/pubmed/26227905 A Pooling Genome-Wide Association Study Combining a Pathway Analysis for Typical Sporadic Parkinson's Disease in the Han Population of Chinese Mainland. Parkinson's disease 250 Han Chinese ancestry cases, 250 Han Chinese ancestry controls NA Illumina [862198] 22 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST003059 Genome-wide genotyping array 500 2016-09-12 26377243 Li J 2015-09-17 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/26377243 Genome- and exome-wide association study of serum lipoprotein (a) in the Jackson Heart Study. Lipoprotein (a) levels 2,895 African American individuals NA Affymetrix [up to 38000000] (imputed) 19 lipoprotein A measurement http://www.ebi.ac.uk/efo/EFO_0006925 GCST003127 Genome-wide genotyping array 2895 2016-05-12 26350878 Tashjian RZ 2015-09-05 J Shoulder Elbow Surg www.ncbi.nlm.nih.gov/pubmed/26350878 Genome-wide association study for rotator cuff tears identifies two significant single-nucleotide polymorphisms. Rotator cuff tears 311 European ancestry cases, 2,641 European ancestry controls NA Illumina [257558] 2 rotator cuff tear http://www.ebi.ac.uk/efo/EFO_1001250 GCST003115 Genome-wide genotyping array 2952 2016-09-07 26398136 Kuo PH 2015-09-23 PLoS One www.ncbi.nlm.nih.gov/pubmed/26398136 Genome-Wide Association Study for Autism Spectrum Disorder in Taiwanese Han Population. Autism spectrum disorder 315 Han Chinese ancestry cases, 1,115 Han Chinese ancestry controls 282 Han Chinese ancestry cases, 480 Han Chinese ancestry controls Affymetrix [546171] 4 autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0003756 GCST003130 Genome-wide genotyping array 1430 2016-09-12 26394188 Zhu Z 2015-09-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26394188 Genome-wide association study identifies new susceptibility loci for adolescent idiopathic scoliosis in Chinese girls. Adolescent idiopathic scoliosis 960 Han Chinese ancestry cases, 1,499 Han Chinese ancestry controls 3,316 Han Chinese ancestry cases, 4,516 Han Chinese ancestry controls Affymetrix [516220] 4 adolescent idiopathic scoliosis http://www.ebi.ac.uk/efo/EFO_0005423 GCST003128 Genome-wide genotyping array 2459 2016-09-12 26379185 Garcia-Etxebarria K 2015-09-17 PLoS One www.ncbi.nlm.nih.gov/pubmed/26379185 No Major Host Genetic Risk Factor Contributed to A(H1N1)2009 Influenza Severity. Influenza A (H1N1) severity 49 European ancestry severe cases, 107 European ancestry mild cases NA Affymetrix [547296] 7 influenza A severity measurement http://www.ebi.ac.uk/efo/EFO_0007743 GCST003126 Genome-wide genotyping array 156 2016-09-12 26379185 Garcia-Etxebarria K 2015-09-17 PLoS One www.ncbi.nlm.nih.gov/pubmed/26379185 No Major Host Genetic Risk Factor Contributed to A(H1N1)2009 Influenza Severity. Influenza A (H1N1) infection 49 European ancestry severe cases, 107 European ancestry mild cases, 549 European ancestry population controls NA Affymetrix [547296] 14 influenza A (H1N1) http://www.ebi.ac.uk/efo/EFO_1001488 GCST003125 Genome-wide genotyping array 705 2016-09-12 26379185 Garcia-Etxebarria K 2015-09-17 PLoS One www.ncbi.nlm.nih.gov/pubmed/26379185 No Major Host Genetic Risk Factor Contributed to A(H1N1)2009 Influenza Severity. Mild influenza (H1N1) infection 107 European ancestry mild cases, 549 European ancestry population controls NA Affymetrix [547296] 35 influenza A (H1N1) http://www.ebi.ac.uk/efo/EFO_1001488 GCST003124 Genome-wide genotyping array 656 2016-09-12 26379185 Garcia-Etxebarria K 2015-09-17 PLoS One www.ncbi.nlm.nih.gov/pubmed/26379185 No Major Host Genetic Risk Factor Contributed to A(H1N1)2009 Influenza Severity. Severe influenza A (H1N1) infection 49 European ancestry severe cases, 549 European ancestry population controls NA Affymetrix [547296] 34 influenza A (H1N1) http://www.ebi.ac.uk/efo/EFO_1001488 GCST003123 Genome-wide genotyping array 598 2016-08-17 26314684 Liu X 2015-08-28 Autism Res www.ncbi.nlm.nih.gov/pubmed/26314684 Genome-wide Association Study of Autism Spectrum Disorder in the East Asian Populations. Autism spectrum disorder 156 Japanese ancestry cases, 620 Japanese ancestry controls 205 Japanese ancestry cases, 184 Japanese ancestry controls, 418 Han Chinese ancestry cases and 836 Han Chinese ancestry controls from 418 trios Affymetrix [561592] 1 autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0003756 GCST003104 Genome-wide genotyping array 776 2016-06-13 26365420 Mbarek H 2015-09-14 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/26365420 The genetics of alcohol dependence: Twin and SNP-based heritability, and genome-wide association study based on AUDIT scores. Alcohol dependence 1,374 European ancestry cases and 6,468 European ancestry controls from 7,694 twin pairs NA Affymetrix, Illumina, Perlegen [6464174] (imputed) 18 alcohol dependence http://www.ebi.ac.uk/efo/EFO_0003829 GCST003121 Genome-wide genotyping array 15536 2016-08-15 26366553 Danjou F 2015-09-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26366553 Genome-wide association analyses based on whole-genome sequencing in Sardinia provide insights into regulation of hemoglobin levels. Hemoglobin levels 6,602 Sardinian founder individuals 4,131 European ancestry individuals Illumina [~ 10900000] (imputed) 8 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST003122 Genome-wide genotyping array 6602 2016-09-07 26323598 Brandl EJ 2015-09-01 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/26323598 Genome-wide association study on antipsychotic-induced weight gain in the CATIE sample. Antipsychotic drug-induced weight gain 189 European ancestry treated schizophrenia cases 86 European ancestry treated schizophrenia or schizoaffective cases Illumina, Perlegen [321290] 1 antipsychotic drug related weight gain http://www.ebi.ac.uk/efo/EFO_0004567 GCST003109 Genome-wide genotyping array 189 2016-09-07 26323598 Brandl EJ 2015-09-01 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/26323598 Genome-wide association study on antipsychotic-induced weight gain in the CATIE sample. Antipsychotic drug-induced weight gain (time interaction) 189 European ancestry treated schizophrenia cases NA Illumina, Perlegen [321290] 1 longitudinal BMI measurement, antipsychotic drug related weight gain http://www.ebi.ac.uk/efo/EFO_0005937, http://www.ebi.ac.uk/efo/EFO_0004567 GCST003108 Genome-wide genotyping array 189 2016-07-23 26198764 Goes FS 2015-07-21 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/26198764 Genome-wide association study of schizophrenia in Ashkenazi Jews. Schizophrenia 1,505 Ashkenazi Jewish founder cases, 2,553 Ashkenazi Jewish founder controls NA Illumina [up to 9792010] (imputed) 29 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST003050 Genome-wide genotyping array 4058 2016-07-23 26198764 Goes FS 2015-07-21 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/26198764 Genome-wide association study of schizophrenia in Ashkenazi Jews. Schizophrenia 592 Ashkenazi Jewish ancestry cases, 505 Ashkenazi Jewish ancestry controls, 36,989 cases, 113,075 controls NA Illumina [7158791] (imputed) 620 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST003048 Genome-wide genotyping array 151161 2016-09-13 26291516 Miller FW 2015-08-20 Genes Immun www.ncbi.nlm.nih.gov/pubmed/26291516 Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes. Myositis 1,710 European ancestry cases, 4,724 European ancestry controls NA Illumina [NR] (imputed) 23 myositis http://www.ebi.ac.uk/efo/EFO_0000783 GCST003092 Genome-wide genotyping array 6434 2016-09-28 26604143 Felix JF 2015-11-24 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26604143 Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Childhood body mass index 34,744 European ancestry children 11,313 European ancestry children Affymetrix, Illumina [2499691] (imputed) 39 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST003177 Genome-wide genotyping array 34744 2016-12-14 27028160 Sherva R 2016-03-30 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/27028160 Genome-wide Association Study of Cannabis Dependence Severity, Novel Risk Variants, and Shared Genetic Risks. Cannabis dependence symptom count Up to 6,000 African American ancestry individuals, 8,754 European ancestry individuals At least 1,893 European ancestry individuals Illumina [NR] (imputed) 30 cannabis dependence measurement http://www.ebi.ac.uk/efo/EFO_0008457 GCST003465 Genome-wide genotyping array 14754 2017-02-10 27339598 Ulveling D 2016-07-29 Hepatology www.ncbi.nlm.nih.gov/pubmed/27339598 A new 3p25 locus is associated with liver fibrosis progression in human immunodeficiency virus/hepatitis C virus-coinfected patients. Liver fibrosis severity in HIV/hepatitis C co-infection 289 French ancestry cases NA Illumina [8426597] (imputed) 7 Hepatic fibrosis http://purl.obolibrary.org/obo/HP_0001395 GCST003606 Genome-wide genotyping array 289 2016-12-13 27020472 Fan Q 2016-03-29 Nat Commun www.ncbi.nlm.nih.gov/pubmed/27020472 Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error. Spherical equivalent (joint analysis main effects and education interaction) 2,604 Erasmus Rucphen population isolate individuals, 456 Sardinian population isolate individuals, 36,976 European ancestry individuals, 5,971 East Asian ancestry individuals, 2,256 Malay ancestry individuals, 2,088 Indian ancestry individuals NA Affymetrix, Illumina [up to 7331415] (imputed) 48 self reported educational attainment, refractive error measurement http://www.ebi.ac.uk/efo/EFO_0004784, http://www.ebi.ac.uk/efo/EFO_0007814 GCST003455 Genome-wide genotyping array 50351 2017-02-24 27402877 Hill-Burns EM 2016-07-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/27402877 Identification of genetic modifiers of age-at-onset for familial Parkinson's disease. Parkinson's disease (non-familial, age at onset) 1,554 European ancestry cases 2,363 European ancestry cases Illumina [7200000] (imputed) 0 Parkinson's disease, age at onset http://www.ebi.ac.uk/efo/EFO_0002508, http://www.ebi.ac.uk/efo/EFO_0004847 GCST003651 Genome-wide genotyping array 1554 2017-02-24 27402877 Hill-Burns EM 2016-07-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/27402877 Identification of genetic modifiers of age-at-onset for familial Parkinson's disease. Parkinson's disease (age of onset) 1985 European ancestry cases 3100 European ancestry cases Illumina [7200000] (imputed) 0 Parkinson's disease, age at onset http://www.ebi.ac.uk/efo/EFO_0002508, http://www.ebi.ac.uk/efo/EFO_0004847 GCST003653 Genome-wide genotyping array 1985 2017-02-24 27402877 Hill-Burns EM 2016-07-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/27402877 Identification of genetic modifiers of age-at-onset for familial Parkinson's disease. Parkinson's disease (familial, age at onset) 431 European ancestry cases 737 European ancestry cases Illumina [7200000] (imputed) 4 Parkinson's disease, age at onset http://www.ebi.ac.uk/efo/EFO_0002508, http://www.ebi.ac.uk/efo/EFO_0004847 GCST003652 Genome-wide genotyping array 431 2016-12-01 27333618 Sekula P 2016-02-04 Nephrol Dial Transplant www.ncbi.nlm.nih.gov/pubmed/27333618 Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies. Membranous nephropathy 323 European ancestry cases, 345 European ancestry controls 137 European ancestry cases, 379 European ancestry controls Illumina [8968426] (imputed) 2 membranous glomerulonephritis http://www.ebi.ac.uk/efo/EFO_0004254 GCST003402 Genome-wide genotyping array 668 2016-12-21 27068588 Chauhan G 2016-04-07 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/27068588 Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies. Ischemic stroke 3,028 European ancestry cases, 80,613 European ancestry controls 2,284 European ancestry cases, 17,184 European ancestry controls, 16,851 African unspecified, Hispanic and European ancestry cases, 32,473 African unspecified, Hispanic and European ancestry controls Affymetrix, Illumina [NR] (imputed) 0 Ischemic stroke http://purl.obolibrary.org/obo/HP_0002140 GCST003492 Genome-wide genotyping array 83641 2016-12-21 27068588 Chauhan G 2016-04-07 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/27068588 Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies. Ischemic stroke (cardioembolic) 602 European ancestry cases, 80,613 European ancestry controls 579 European ancestry cases, 3,427 African unspecified, Hispanic and European ancestry cases, 18,515 European ancestry controls, 32,473 African unspecified, Hispanic and European ancestry controls Affymetrix, Illumina [NR] (imputed) 1 Ischemic stroke, cardiac embolism http://purl.obolibrary.org/obo/HP_0002140, http://www.ebi.ac.uk/efo/EFO_1001493 GCST003490 Genome-wide genotyping array 81215 2016-12-21 27068588 Chauhan G 2016-04-07 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/27068588 Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies. Ischemic stroke (non-cardioembolic) 1,770 European ancestry cases, 80,613 European ancestry controls 335 European ancestry large-vessel ischaemic stroke cases, 365 European ancestry small-vessel ischaemic stroke cases, 2,346 African unspecified, Hispanic and European ancestry large-vessel ischaemic stroke cases, 3,150 African unspecified, Hispanic and European ancestry small-vessel ischaemic stroke cases, 18,515 European ancestry controls, 32,473 African unspecified, Hispanic and European ancestry controls Affymetrix, Illumina [NR] (imputed) 0 Ischemic stroke http://purl.obolibrary.org/obo/HP_0002140 GCST003493 Genome-wide genotyping array 82383 2016-12-21 27068588 Chauhan G 2016-04-07 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/27068588 Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies. Stroke 4,348 European ancestry cases, 80,613 European ancestry controls 681 European ancestry cases, 1,331 European ancestry controls Affymetrix, Illumina [NR] (imputed) 1 stroke http://www.ebi.ac.uk/efo/EFO_0000712 GCST003491 Genome-wide genotyping array 84961 2017-02-24 27036123 van Leeuwen EM 2016-04-01 J Med Genet www.ncbi.nlm.nih.gov/pubmed/27036123 Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels. Triglycerides 41,142 European ancestry individuals, 705 East Asian ancestry individuals, 6,287 African American individuals, 1,415 Hispanic individuals 60,827 European ancestry individuals, 9,982 Indian Asian ancestry individuals, 2,710 African American/Afro-Caribbean individuals Affymetrix, Illumina [NR] (imputed) 29 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST003661 Genome-wide genotyping array 49549 2017-02-24 27036123 van Leeuwen EM 2016-04-01 J Med Genet www.ncbi.nlm.nih.gov/pubmed/27036123 Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels. LDL cholesterol 40,473 European ancestry individuals, 689 East Asian ancestry individuals, 6,237 African American individuals, 1,381 Hispanic individuals 60,078 European ancestry individuals, 9,729 Indian Asian ancestry individuals, 2,679 African American/Afro-Caribbean individuals Affymetrix, Illumina [NR] (imputed) 31 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST003662 Genome-wide genotyping array 48780 2017-02-24 27036123 van Leeuwen EM 2016-04-01 J Med Genet www.ncbi.nlm.nih.gov/pubmed/27036123 Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels. Cholesterol, total 51,430 European ancestry individuals, 702 East Asian ancestry individuals, 6,480 African American individuals, 1,412 Hispanic individuals 71,032 European ancestry individuals, 10,000 Indian Asian ancestry individuals, 2,707 African American/Afro-Caribbean individuals Affymetrix, Illumina [NR] (imputed) 45 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST003663 Genome-wide genotyping array 60024 2017-02-24 27036123 van Leeuwen EM 2016-04-01 J Med Genet www.ncbi.nlm.nih.gov/pubmed/27036123 Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels. HDL cholesterol 50,823 European ancestry individuals, 703 East Asian ancestry individuals, 6,476 African American individuals, 1,407 Hispanic individuals 71,921 European ancestry individuals, 9,992 Indian Asian ancestry individuals, 2,685 African American/Afro-Caribbean individuals Affymetrix, Illumina [NR] (imputed) 37 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST003660 Genome-wide genotyping array 59409 2017-03-30 27494321 Jones SE 2016-08-05 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/27494321 Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci. Chronotype 127,898 British individuals 89,283 individuals NR [16760980] (imputed) 14 circadian rhythm http://www.ebi.ac.uk/efo/EFO_0004354 GCST003837 Genome-wide genotyping array 127898 2017-03-30 27494321 Jones SE 2016-08-05 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/27494321 Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci. Sleep duration 127,573 British individuals 47,180 individuals NR [16761225] (imputed) 3 sleep duration http://www.ebi.ac.uk/efo/EFO_0005271 GCST003839 Genome-wide genotyping array 127573 2017-03-30 27494321 Jones SE 2016-08-05 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/27494321 Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci. Morning vs. evening chronotype 114,765 British individuals NA NR [16760980] (imputed) 15 circadian rhythm http://www.ebi.ac.uk/efo/EFO_0004354 GCST003838 Genome-wide genotyping array 114765 2017-03-30 27494321 Jones SE 2016-08-05 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/27494321 Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci. Sleep duration (oversleepers vs undersleepers) 10,102 British oversleeper individuals, 28,980 British undersleeper indivdiuals NA NR [16761225] (imputed) 2 sleep duration http://www.ebi.ac.uk/efo/EFO_0005271 GCST003840 Genome-wide genotyping array 39082 2018-12-07 27494321 Jones SE 2016-08-05 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/27494321 Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci. Sleep duration (oversleepers) 10,102 British ancestry cases, 81,204 British ancestry controls NA NR [16761225] (imputed) 0 sleep duration http://www.ebi.ac.uk/efo/EFO_0005271 GCST006685 Genome-wide genotyping array 91306 2018-12-07 27494321 Jones SE 2016-08-05 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/27494321 Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci. Sleep duration (undersleepers) 28,980 British ancestry cases, 81,208 British ancestry controls NA NR [16761225] (imputed) 0 sleep duration http://www.ebi.ac.uk/efo/EFO_0005271 GCST006686 Genome-wide genotyping array 110188 2017-01-13 27135401 Cheng TH 2016-05-02 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27135401 Five endometrial cancer risk loci identified through genome-wide association analysis. Endometrial endometrioid carcinoma 2,082 European ancestry cases, 9,544 European ancestry controls 4,553 European ancestry cases, 27,600 European ancestry controls Illumina [up to 2300000] (imputed) 7 endometrial endometrioid carcinoma http://www.ebi.ac.uk/efo/EFO_1001514 GCST003525 Genome-wide genotyping array 11626 2017-01-13 27135401 Cheng TH 2016-05-02 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27135401 Five endometrial cancer risk loci identified through genome-wide association analysis. Endometrial cancer 2,082 European ancestry endometrioid cases, 130 European ancestry cases, 9,544 European ancestry controls 4,553 European ancestry endometrioid cases, 972 European ancestry cases, 27,600 European ancestry controls Illumina [up to 2300000] (imputed) 8 endometrial carcinoma http://www.ebi.ac.uk/efo/EFO_1001512 GCST003524 Genome-wide genotyping array 11756 2017-04-06 27883235 Martino DJ 2017-01-11 Clin Exp Allergy www.ncbi.nlm.nih.gov/pubmed/27883235 Genomewide association study of peanut allergy reproduces association with amino acid polymorphisms in HLA-DRB1. Peanut allergy 51 European ancestry infant cases, 14 Asian ancestry infant cases, 8 mixed European/Asian infant cases, 119 European ancestry non-allergic infant controls, 10 Asian ancestry non-allergic infant controls, 19 mixed European/Asian non-allergic infant controls 604 European ancestry infant cases, 34 mixed European/Asian infant cases, 2,871 European ancestry non-allergic infant controls, 40 mixed European/Asian non-allergic infant controls, 589 European ancestry infant controls, 1,148 European ancestry parent controls Illumina [3814967] (imputed) 0 peanut allergy measurement http://www.ebi.ac.uk/efo/EFO_0007017 GCST003881 Genome-wide genotyping array 221 2016-12-01 27016271 Kornilov SA 2016-03-25 Pediatrics www.ncbi.nlm.nih.gov/pubmed/27016271 Genome-Wide Association and Exome Sequencing Study of Language Disorder in an Isolated Population. Developmental language disorder 149 isolated population cases, 210 isolated population controls NA Illumina [223580] 4 specific language impairment http://www.ebi.ac.uk/efo/EFO_1001510 GCST003396 Genome-wide genotyping array 359 2016-12-01 27016271 Kornilov SA 2016-03-25 Pediatrics www.ncbi.nlm.nih.gov/pubmed/27016271 Genome-Wide Association and Exome Sequencing Study of Language Disorder in an Isolated Population. Developmental language disorder (linguistic errors) 149 isolated population cases, 210 isolated population controls NA Illumina [223580] 9 linguistic error measurement, specific language impairment http://www.ebi.ac.uk/efo/EFO_0007798, http://www.ebi.ac.uk/efo/EFO_1001510 GCST003397 Genome-wide genotyping array 359 2016-12-01 27016271 Kornilov SA 2016-03-25 Pediatrics www.ncbi.nlm.nih.gov/pubmed/27016271 Genome-Wide Association and Exome Sequencing Study of Language Disorder in an Isolated Population. Developmental language disorder (syntactic complexity) 149 isolated population cases, 210 isolated population controls NA Illumina [223580] 3 syntactic complexity measurement, specific language impairment http://www.ebi.ac.uk/efo/EFO_0007799, http://www.ebi.ac.uk/efo/EFO_1001510 GCST003398 Genome-wide genotyping array 359 2016-12-09 27043157 Keers R 2016-04-05 Psychother Psychosom www.ncbi.nlm.nih.gov/pubmed/27043157 A Genome-Wide Test of the Differential Susceptibility Hypothesis Reveals a Genetic Predictor of Differential Response to Psychological Treatments for Child Anxiety Disorders. Discordance in emotional problems in monozygotic twins up to 1,026 child monozygotic twin pairs NA Affymetrix [679050] 6 emotional symptom measurement http://www.ebi.ac.uk/efo/EFO_0007803 GCST003437 Genome-wide genotyping array 1026 2017-01-13 27157822 Hallberg P 2016-05-03 Lancet Diabetes Endocrinol www.ncbi.nlm.nih.gov/pubmed/27157822 Genetic variants associated with antithyroid drug-induced agranulocytosis: a genome-wide association study in a European population. Anti-thyroid drug induced agranulocytosis 38 European ancestry cases, 1 case, 5,170 European ancestry controls NA Illumina [9380034] (imputed) 6 response to anti-thyroid drug, Drug-induced agranulocytosis http://www.ebi.ac.uk/efo/EFO_0007838, http://purl.obolibrary.org/obo/HP_0012235 GCST003527 Genome-wide genotyping array 5209 2017-01-13 27157822 Hallberg P 2016-05-03 Lancet Diabetes Endocrinol www.ncbi.nlm.nih.gov/pubmed/27157822 Genetic variants associated with antithyroid drug-induced agranulocytosis: a genome-wide association study in a European population. Non-chemotherapy drug induced agranulocytosis 222 European ancestry cases, 12 cases, 5,170 European ancestry controls NA Illumina [9380034] (imputed) 5 response to drug, Drug-induced agranulocytosis http://purl.obolibrary.org/obo/GO_0042493, http://purl.obolibrary.org/obo/HP_0012235 GCST003526 Genome-wide genotyping array 5404 2016-12-19 26959369 Haiman CA 2016-03-09 PLoS One www.ncbi.nlm.nih.gov/pubmed/26959369 Benzene Uptake and Glutathione S-transferase T1 Status as Determinants of S-Phenylmercapturic Acid in Cigarette Smokers in the Multiethnic Cohort. S-phenylmercapturic acid levels in smokers 364 African American current smoker individuals, 311 Native Hawaiian ancestry current smoker individuals, 437 European ancestry current smoker individuals, 453 Latino ancestry current smoker individuals, 674 Japanese American ancestry current smoker individuals NA Illumina [11892802] (imputed) 3 urinary S-phenylmercapturic acid measurement http://www.ebi.ac.uk/efo/EFO_0007651 GCST003483 Genome-wide genotyping array 2239 2017-03-28 27764800 Cox DG 2016-10-14 Oncotarget www.ncbi.nlm.nih.gov/pubmed/27764800 GWAS in the SIGNAL/PHARE clinical cohort restricts the association between the FGFR2 locus and estrogen receptor status to HER2-negative breast cancer patients. Estrogen receptor status in HER2 positive breast cancer 1,944 French ancestry estrogen receptor positive cases, 1,331 French ancestry estrogen receptor negative cases NA Illumina [914144] (imputed) 0 estrogen receptor status http://www.ebi.ac.uk/efo/EFO_0005512 GCST003822 Genome-wide genotyping array 3275 2017-03-28 27764800 Cox DG 2016-10-14 Oncotarget www.ncbi.nlm.nih.gov/pubmed/27764800 GWAS in the SIGNAL/PHARE clinical cohort restricts the association between the FGFR2 locus and estrogen receptor status to HER2-negative breast cancer patients. Estrogen receptor status in HER2 negative breast cancer 4,267 French ancestry estrogen receptor positive cases, 1,185 French ancestry estrogen receptor negative cases NA Illumina [914144] (imputed) 1 estrogen receptor status http://www.ebi.ac.uk/efo/EFO_0005512 GCST003823 Genome-wide genotyping array 5452 2017-03-28 27764800 Cox DG 2016-10-14 Oncotarget www.ncbi.nlm.nih.gov/pubmed/27764800 GWAS in the SIGNAL/PHARE clinical cohort restricts the association between the FGFR2 locus and estrogen receptor status to HER2-negative breast cancer patients. Estrogen receptor status in breast cancer 6,211 French ancestry estrogen receptor positive cases, 2,516 French ancestry estrogen receptor negative cases NA Illumina [914144] (imputed) 1 estrogen receptor status http://www.ebi.ac.uk/efo/EFO_0005512 GCST003821 Genome-wide genotyping array 8727 2017-02-24 27296613 Salinas YD 2016-06-13 BMC Genet www.ncbi.nlm.nih.gov/pubmed/27296613 Multiethnic genome-wide association study identifies ethnic-specific associations with body mass index in Hispanics and African Americans. Body mass index 1,235 Hispanic individuals, 706 Asian ancestry individuals, 1,549 African American individuals, 2,395 European ancestry individuals 3,379 Hispanic individuals, 6,871 African American individuals Affymetrix [up to 871948] 4 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST003647 Genome-wide genotyping array 5885 2017-03-24 27802415 Salvi E 2016-10-31 Hypertension www.ncbi.nlm.nih.gov/pubmed/27802415 Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide. Diastolic blood pressure response to hydrochlorothiazide in hypertension 1,739 European ancestry individuals 430 African American individuals Affymetrix, Illumina [up to 2500000] (imputed) 8 response to hydrochlorothiazide, diastolic blood pressure change measurement http://www.ebi.ac.uk/efo/EFO_0005202, http://www.ebi.ac.uk/efo/EFO_0006945 GCST003805 Genome-wide genotyping array 1739 2017-03-24 27802415 Salvi E 2016-10-31 Hypertension www.ncbi.nlm.nih.gov/pubmed/27802415 Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide. Systolic blood pressure response to hydrochlorothiazide in hypertension 1,739 European ancestry individuals 430 African American individuals Affymetrix, Illumina [up to 2500000] (imputed) 10 response to hydrochlorothiazide, systolic blood pressure change measurement http://www.ebi.ac.uk/efo/EFO_0005202, http://www.ebi.ac.uk/efo/EFO_0006944 GCST003807 Genome-wide genotyping array 1739 2016-12-21 27046643 Davies G 2016-04-05 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/27046643 Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151). Memory performance 112,067 European ancestry individuals NA Affymetrix [~ 17300000] (imputed) 0 memory performance http://www.ebi.ac.uk/efo/EFO_0004874 GCST003497 Genome-wide genotyping array 112067 2016-12-21 27046643 Davies G 2016-04-05 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/27046643 Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151). Verbal-numerical reasoning 36,035 European ancestry individuals NA Affymetrix [~ 17300000] (imputed) 3 reasoning http://www.ebi.ac.uk/efo/EFO_0004350 GCST003498 Genome-wide genotyping array 36035 2016-12-21 27046643 Davies G 2016-04-05 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/27046643 Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151). Educational attainment 111,114 European ancestry individuals NA Affymetrix [~ 17300000] (imputed) 15 self reported educational attainment http://www.ebi.ac.uk/efo/EFO_0004784 GCST003496 Genome-wide genotyping array 111114 2016-12-21 27046643 Davies G 2016-04-05 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/27046643 Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151). Reaction time 111,483 European ancestry individuals NA Affymetrix [~ 17300000] (imputed) 2 reaction time measurement http://www.ebi.ac.uk/efo/EFO_0008393 GCST003499 Genome-wide genotyping array 111483 2017-02-22 27304844 Khong JJ 2016-06-01 Invest Ophthalmol Vis Sci www.ncbi.nlm.nih.gov/pubmed/27304844 Association of Polymorphisms in MACRO Domain Containing 2 With Thyroid-Associated Orbitopathy. Thyroid-associated orbitopathy in graves' disease 265 European ancestry cases with thyroid-associated orbitopathy, 147 European ancestry cases without thyroid-associated orbitopathy 319 European ancestry cases with thyroid-associated orbitopathy, 220 European ancestry cases without thyroid-associated orbitopathy Illumina [2200000] 1 Graves ophthalmopathy http://www.ebi.ac.uk/efo/EFO_1001466 GCST003640 Genome-wide genotyping array 412 2016-11-01 27179730 Allen NB 2016-01-23 Am Heart J www.ncbi.nlm.nih.gov/pubmed/27179730 Genetic loci associated with ideal cardiovascular health: A meta-analysis of genome-wide association studies. Ideal cardiovascular health (clinical and behavioural) 883 European ancestry individuals with clinical and behavioral ideal cardiovascular health, 10,825 European ancestry individuals without clinical and behavioral ideal cardiovascular health 522 European ancestry individuals Affymetrix [~ 25000000] (imputed) 1 clinical and behavioural ideal cardiovascular health http://www.ebi.ac.uk/efo/EFO_0007654 GCST003278 Genome-wide genotyping array 11708 2016-11-01 27179730 Allen NB 2016-01-23 Am Heart J www.ncbi.nlm.nih.gov/pubmed/27179730 Genetic loci associated with ideal cardiovascular health: A meta-analysis of genome-wide association studies. Ideal cardiovascular health (clinical) 2,242 European ancestry individuals with clinical ideal cardiovascular health, 9,466 European ancestry individuals without clinical ideal cardiovascular health 522 European ancestry individuals Affymetrix [~ 25000000] (imputed) 1 clinical ideal cardiovascular health http://www.ebi.ac.uk/efo/EFO_0007653 GCST003279 Genome-wide genotyping array 11708 2019-09-11 26546613 Gutierrez-Achury J 2016-01-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/26546613 Functional implications of disease-specific variants in loci jointly associated with coeliac disease and rheumatoid arthritis. Celiac disease and Rheumatoid arthritis 371 South Asian ancestry celiac disease cases, 3,138 European ancestry celiac disease cases, 4,418 European ancestry rheumatoid arthritis cases, 509 South Asian ancestry celiac disease controls, 2,473 European ancestry celiac disease controls, 3,300 European ancestry rheumatoid arthritis controls, 8,872 celiac disease cases, 9,401 rheumatoid arthritis cases, 4,845 celiac disease controls, 9,627 rheumatoid arthritis controls NA Illumina [109572] 24 rheumatoid arthritis, celiac disease http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0001060 GCST008644 Targeted genotyping array [Immunochip] 46954 2017-02-21 27193062 Adhikari K 2016-05-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/27193062 A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation. middle facial morphology traits (ordinal measurement) 5,958 Latin American ancestry individuals 501 Latin American ancestry individuals Illumina [9117642] (imputed) 0 nose morphology measurement, cheekbone morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843, http://www.ebi.ac.uk/efo/EFO_0007847 GCST003633 Genome-wide genotyping array 5958 2017-02-21 27193062 Adhikari K 2016-05-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/27193062 A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation. lower facial morphology traits (ordinal measurement) 5,958 Latin American ancestry individuals. NA Illumina [9117642] (imputed) 0 lip morphology measurement, chin morphology measurement http://www.ebi.ac.uk/efo/EFO_0007845, http://www.ebi.ac.uk/efo/EFO_0007842 GCST003634 Genome-wide genotyping array 5958 2017-02-21 27193062 Adhikari K 2016-05-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/27193062 A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation. middle facial morphology traits (quantitative measurement) 2955 Latin American ancestry individuals. NA Illumina [9117642] (imputed) 7 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST003635 Genome-wide genotyping array 2955 2017-02-21 27193062 Adhikari K 2016-05-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/27193062 A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation. lower facial morphology traits (quantitative measurement) 2955 Latin American ancestry individuals. NA Illumina [9117642] (imputed) 1 lip morphology measurement, chin morphology measurement http://www.ebi.ac.uk/efo/EFO_0007845, http://www.ebi.ac.uk/efo/EFO_0007842 GCST003636 Genome-wide genotyping array 2955 2017-02-21 27193062 Adhikari K 2016-05-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/27193062 A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation. facial morphology traits (multivariate analysis) 5,958 Latin American ancestry individuals. NA Illumina [9117642] (imputed) 4 facial morphology measurement http://www.ebi.ac.uk/efo/EFO_0007841 GCST003637 Genome-wide genotyping array 5958 2017-02-21 27193062 Adhikari K 2016-05-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/27193062 A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation. upper facial morphology traits (ordinal measurement) 5,958 Latin American ancestry individuals. NA Illumina [9117642] (imputed) 0 forehead morphology measurement http://www.ebi.ac.uk/efo/EFO_0007844 GCST003638 Genome-wide genotyping array 5958 2018-07-13 26525574 Westerlind H 2015-11-02 Gut www.ncbi.nlm.nih.gov/pubmed/26525574 Dense genotyping of immune-related loci identifies HLA variants associated with increased risk of collagenous colitis. Collagenous colitis 247 European ancestry cases, 3969 European ancestry controls 67 European ancestry cases, 330 European ancestry controls Illumina [110634] 1 collagenous colitis http://www.ebi.ac.uk/efo/EFO_1001293 GCST005879 Targeted genotyping array [Immunochip] 4216 2017-02-19 27488534 Patel YM 2016-08-03 Cancer Res www.ncbi.nlm.nih.gov/pubmed/27488534 Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk. Nicotine metabolite ratio in current smokers 437 European ancestry individuals, 364 African American individuals, 453 Latino individuals, 674 Japanese American individuals, 311 Native Hawaiian ancestry individuals NA Illumina [11892802] (imputed) 14 nicotine metabolite ratio http://www.ebi.ac.uk/efo/EFO_0007794 GCST003629 Genome-wide genotyping array 2239 2017-03-10 27322543 Gormley P 2016-06-20 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27322543 Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. Migraine 59,674 European ancestry cases, 316,078 European ancestry controls NA Affymetrix, Illumina, Perlegen [8094889] (imputed) 44 migraine disorder http://www.ebi.ac.uk/efo/EFO_0003821 GCST003720 Genome-wide genotyping array 375752 2017-03-10 27322543 Gormley P 2016-06-20 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27322543 Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. Migraine without aura 8,348 European ancestry cases, 139,622 European ancestry controls NA Affymetrix, Illumina, Perlegen [8094889] (imputed) 7 migraine without aura http://www.ebi.ac.uk/efo/EFO_0005296 GCST003721 Genome-wide genotyping array 147970 2017-03-10 27322543 Gormley P 2016-06-20 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27322543 Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. Migraine with aura 6,332 European ancestry cases, 144,883 European ancestry controls NA Affymetrix, Illumina, Perlegen [8094889] (imputed) 0 migraine with aura http://www.ebi.ac.uk/efo/EFO_0005295 GCST003722 Genome-wide genotyping array 151215 2017-02-24 27236921 Rautanen A 2016-06-02 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27236921 Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children. Pneumococcal bacteremia 429 African ancestry cases, 2,677 African ancestry controls 113 African ancestry cases, 1,336 African ancestry controls Affymetrix [up to 10996499] (imputed) 9 pneumococcal bacteremia http://www.ebi.ac.uk/efo/EFO_1001925 GCST003649 Genome-wide genotyping array 3106 2017-02-24 27236921 Rautanen A 2016-06-02 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27236921 Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children. Bacteremia 1,536 African ancestry cases, 2,677 African ancestry controls 434 African ancestry cases, 1,336 African ancestry controls Affymetrix [up to 10996499] (imputed) 12 bacteriemia http://www.ebi.ac.uk/efo/EFO_0003033 GCST003650 Genome-wide genotyping array 4213 2017-02-24 27005778 Kettunen J 2016-03-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/27005778 Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA. Metabolite levels (lipid measures) 2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals NA Affymetrix, Illumina, Perlegen [12133295] (imputed) 6 lipid measurement, blood metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004529, http://www.ebi.ac.uk/efo/EFO_0005664 GCST003664 Genome-wide genotyping array 24925 2017-02-24 27005778 Kettunen J 2016-03-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/27005778 Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA. Metabolite levels (small molecules and protein measures) 2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals NA Affymetrix, Illumina, Perlegen [12133295] (imputed) 33 blood metabolite measurement, protein measurement, amino acid measurement http://www.ebi.ac.uk/efo/EFO_0005664, http://www.ebi.ac.uk/efo/EFO_0004747, http://www.ebi.ac.uk/efo/EFO_0005134 GCST003666 Genome-wide genotyping array 24925 2017-02-24 27005778 Kettunen J 2016-03-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/27005778 Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA. Metabolite levels (lipoprotein measures) 2,118 Erasmus Rucphen (founder/genetic isolate), 22,807 European ancestry individuals NA Affymetrix, Illumina, Perlegen [12133295] (imputed) 35 lipoprotein measurement, blood metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004732, http://www.ebi.ac.uk/efo/EFO_0005664 GCST003665 Genome-wide genotyping array 24925 2016-12-22 27114598 Liu C 2016-04-25 J Clin Oncol www.ncbi.nlm.nih.gov/pubmed/27114598 Clinical and Genetic Risk Factors for Acute Pancreatitis in Patients With Acute Lymphoblastic Leukemia. Asparaginase-induced acute pancreatitis in acute lymphoblastic leukemia 71 cases with pancreatitis, 142 cases without pancreatitis NA Affymetrix [at least 751455] 0 asparaginase-induced acute pancreatitis http://www.ebi.ac.uk/efo/EFO_1001507 GCST003500 Genome-wide genotyping array 213 2016-12-22 27114598 Liu C 2016-04-25 J Clin Oncol www.ncbi.nlm.nih.gov/pubmed/27114598 Clinical and Genetic Risk Factors for Acute Pancreatitis in Patients With Acute Lymphoblastic Leukemia. Asparaginase-induced acute pancreatitis in acute lymphoblastic leukemia (onset time) 46 European ancestry cases with pancreatitis, 3,023 European ancestry cases without pancreatitis, 11 Black cases with pancreatitis, 339 Black cases without pancreatitis, 46 Hispanic cases with pancreatitis, 1,131 Hispanic cases without pancreatitis, 1 Asian ancestry case with pancreatitis, 98 Asian ancestry cases without pancreatitis, 13 cases with with pancreatitis, 477 cases without pancreatitis NA Affymetrix [at least 751455] 11 asparaginase-induced acute pancreatitis http://www.ebi.ac.uk/efo/EFO_1001507 GCST003501 Genome-wide genotyping array 5185 2017-05-11 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Subcutaneous adipose tissue 7,399 European ancestry women, 7,381 European ancestry men, 2,163 African American women, 1,304 African American men NA Affymetrix, Illumina [~ 2600000] (imputed) 1 subcutaneous adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004766 GCST003965 Genome-wide genotyping array 18247 2017-05-11 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Visceral adipose tissue 7,431 European ancestry women, 7,432 European ancestry men, 2,163 African American women, 1,306 African American men NA Affymetrix, Illumina [~ 2600000] (imputed) 0 visceral adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004765 GCST003966 Genome-wide genotyping array 18332 2017-05-11 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Pericardial adipose tissue adjusted for height and weight 3,684 European ancestry women, 3,640 European ancestry men, 1,284 African American women, 877 African American men, 746 Hispanic Ancestry women, 699 Hispanic ancestry men, 390 Asian ancestry women, 378 Asian ancestry men, 294 Old Order Amish (founder/genetic isolate) women, 248 Old Order Amish (founder/genetic isolate) men. NA Affymetrix, Illumina [~ 2600000] (imputed) 5 pericardial adipose tissue measurement, body weight, body height http://www.ebi.ac.uk/efo/EFO_0007890, http://www.ebi.ac.uk/efo/EFO_0004338, http://www.ebi.ac.uk/efo/EFO_0004339 GCST003968 Genome-wide genotyping array 12240 2017-05-11 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Visceral adipose tissue adjusted for BMI 7,431 European ancestry women, 7,432 European ancestry men, 2,163 African American women, 1,306 African American men NA Affymetrix, Illumina [~ 2600000] (imputed) 2 visceral adipose tissue measurement, body mass index http://www.ebi.ac.uk/efo/EFO_0004765, http://www.ebi.ac.uk/efo/EFO_0004340 GCST003967 Genome-wide genotyping array 18332 2017-05-11 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Pericardial fat 3,684 European ancestry women, 3,640 European ancestry men, 1,284 African American women, 877 African American men, 746 Hispanic Ancestry women, 699 Hispanic ancestry men, 390 Asian ancestry women, 378 Asian ancestry men, 294 Old Order Amish (founder/genetic isolate) women, 248 Old Order Amish (founder/genetic isolate) men. NA Affymetrix, Illumina [~ 2600000] (imputed) 2 pericardial adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0007890 GCST003971 Genome-wide genotyping array 12240 2017-05-11 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Subcutaneous adipose tissue attenuation (Hounsfield unit scale) 5,699 European ancestry women, 5,699 European ancestry men, 592 African American women, 449 African American men. NA Affymetrix, Illumina [~ 2600000] (imputed) 0 subcutaneous adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004766 GCST003970 Genome-wide genotyping array 12439 2017-05-11 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Visceral adipose tissue attenuation (Hounslow unit scale) 5,729 European ancestry women, 5,749 European ancestry men, 592 African American women, 449 African American men. NA Affymetrix, Illumina [~ 2600000] (imputed) 0 visceral adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004765 GCST003969 Genome-wide genotyping array 12519 2017-05-11 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Visceral adipose tissue/subcutaneous adipose tissue ratio 7,618 European ancestry women, 7,050 European ancestry men, 2,205 African American women, 1,324 African American men. NA Affymetrix, Illumina [~ 2600000] (imputed) 4 visceral:subcutaneous adipose tissue ratio http://www.ebi.ac.uk/efo/EFO_0004767 GCST003972 Genome-wide genotyping array 18197 2017-05-11 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Visceral adipose tissue/subcutaneous adipose tissue ratio adjusted for BMI 7,618 European ancestry women, 7,050 European ancestry men, 2,205 African American women, 1,324 African American men. NA Affymetrix, Illumina [~ 2600000] (imputed) 4 body mass index, visceral:subcutaneous adipose tissue ratio http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004767 GCST003973 Genome-wide genotyping array 18197 2018-11-09 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Visceral adipose tissue adjusted for BMI 7,432 European ancestry men, 1,306 African American men NA Affymetrix, Illumina [~ 2600000] (imputed) 1 visceral adipose tissue measurement, body mass index http://www.ebi.ac.uk/efo/EFO_0004765, http://www.ebi.ac.uk/efo/EFO_0004340 GCST006534 Genome-wide genotyping array 8738 2018-11-09 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Visceral adipose tissue adjusted for BMI 7,431 European ancestry women, 2,163 African American women NA Affymetrix, Illumina [~ 2600000] (imputed) 2 visceral adipose tissue measurement, body mass index http://www.ebi.ac.uk/efo/EFO_0004765, http://www.ebi.ac.uk/efo/EFO_0004340 GCST006533 Genome-wide genotyping array 9594 2018-11-09 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Subcutaneous adipose tissue 7,399 European ancestry women, 2,163 African American women NA Affymetrix, Illumina [~ 2600000] (imputed) 1 subcutaneous adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004766 GCST006537 Genome-wide genotyping array 9562 2018-11-09 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Subcutaneous adipose tissue 7,381 European ancestry men, 1,304 African American men NA Affymetrix, Illumina [~ 2600000] (imputed) 0 subcutaneous adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004766 GCST006538 Genome-wide genotyping array 8685 2018-11-09 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Subcutaneous adipose tissue attenuation (Hounsfield unit scale) 5,699 European ancestry men, 449 African American men NA Affymetrix, Illumina [~ 2600000] (imputed) 2 subcutaneous adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004766 GCST006549 Genome-wide genotyping array 6148 2018-11-09 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Pericardial fat 3,640 European ancestry men, 877 African American men, 699 Hispanic ancestry men, 378 Asian ancestry men, 248 Old Order Amish (founder/genetic isolate) men NA Affymetrix, Illumina [~ 2600000] (imputed) 0 pericardial adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0007890 GCST006545 Genome-wide genotyping array 5842 2018-11-09 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Pericardial fat 3,684 European ancestry women, 1,284 African American women, 746 Hispanic Ancestry women, 390 Asian ancestry women, 294 Old Order Amish (founder/genetic isolate) women NA Affymetrix, Illumina [~ 2600000] (imputed) 0 pericardial adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0007890 GCST006546 Genome-wide genotyping array 6398 2018-11-09 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Visceral adipose tissue attenuation (Hounslow unit scale) 5,749 European ancestry men, 449 African American men NA Affymetrix, Illumina [~ 2600000] (imputed) 1 visceral adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004765 GCST006547 Genome-wide genotyping array 6198 2018-11-09 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Visceral adipose tissue attenuation (Hounslow unit scale) 5,729 European ancestry women, 592 African American women NA Affymetrix, Illumina [~ 2600000] (imputed) 0 visceral adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004765 GCST006548 Genome-wide genotyping array 6321 2018-11-09 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Visceral adipose tissue/subcutaneous adipose tissue ratio 7,050 European ancestry men, 1,324 African American men NA Affymetrix, Illumina [~ 2600000] (imputed) 0 visceral:subcutaneous adipose tissue ratio http://www.ebi.ac.uk/efo/EFO_0004767 GCST006552 Genome-wide genotyping array 8374 2018-11-09 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Visceral adipose tissue/subcutaneous adipose tissue ratio 7,618 European ancestry women, 2,205 African American women NA Affymetrix, Illumina [~ 2600000] (imputed) 0 visceral:subcutaneous adipose tissue ratio http://www.ebi.ac.uk/efo/EFO_0004767 GCST006551 Genome-wide genotyping array 9823 2018-11-09 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Visceral adipose tissue 7,432 European ancestry men, 1,306 African American men NA Affymetrix, Illumina [~ 2600000] (imputed) 0 visceral adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004765 GCST006540 Genome-wide genotyping array 8738 2018-11-09 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Visceral adipose tissue 7,431 European ancestry women, 2,163 African American women NA Affymetrix, Illumina [~ 2600000] (imputed) 1 visceral adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004765 GCST006542 Genome-wide genotyping array 9594 2018-11-09 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Pericardial adipose tissue adjusted for height and weight 3,640 European ancestry men, 877 African American men, 699 Hispanic ancestry men, 378 Asian ancestry men, 248 Old Order Amish (founder/genetic isolate) men. NA Affymetrix, Illumina [~ 2600000] (imputed) 1 pericardial adipose tissue measurement, body weight, body height http://www.ebi.ac.uk/efo/EFO_0007890, http://www.ebi.ac.uk/efo/EFO_0004338, http://www.ebi.ac.uk/efo/EFO_0004339 GCST006543 Genome-wide genotyping array 5842 2018-11-09 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Pericardial adipose tissue adjusted for height and weight 3,684 European ancestry women, 1,284 African American women, 746 Hispanic Ancestry women, 390 Asian ancestry women, 294 Old Order Amish (founder/genetic isolate) women NA Affymetrix, Illumina [~ 2600000] (imputed) 3 pericardial adipose tissue measurement, body weight, body height http://www.ebi.ac.uk/efo/EFO_0007890, http://www.ebi.ac.uk/efo/EFO_0004338, http://www.ebi.ac.uk/efo/EFO_0004339 GCST006544 Genome-wide genotyping array 6398 2018-11-09 27918534 Chu AY 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918534 Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Subcutaneous adipose tissue attenuation (Hounsfield unit scale) 5,699 European ancestry women, 592 African American women NA Affymetrix, Illumina [~ 2600000] (imputed) 0 subcutaneous adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004766 GCST006550 Genome-wide genotyping array 6291 2017-02-19 27400856 Legge SE 2016-07-12 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/27400856 Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia. Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia 48 European ancestry cases, 18 European ancestry extreme cases, 5,583 European ancestry controls 161 cases, 249 clozapine-exposed controls, 947 unexposed controls Illumina [7559010] (imputed) 10 Drug-induced agranulocytosis http://purl.obolibrary.org/obo/HP_0012235 GCST003628 Genome-wide genotyping array 5649 2017-04-05 27927781 Robinson-Cohen C 2016-12-07 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/27927781 Genetic Variants Associated with Circulating Parathyroid Hormone. Serum parathyroid hormone levels up to 22,653 European ancestry individuals. 6,502 European ancestry individuals. Affymetrix, Illumina, Perlegen [8559187] (imputed) 6 parathyroid hormone measurement http://www.ebi.ac.uk/efo/EFO_0004752 GCST003879 Genome-wide genotyping array 22653 2017-01-16 27897004 Verma SS 2016-01-01 Pac Symp Biocomput www.ncbi.nlm.nih.gov/pubmed/27897004 IDENTIFYING GENETIC ASSOCIATIONS WITH VARIABILITY IN METABOLIC HEALTH AND BLOOD COUNT LABORATORY VALUES: DIVING INTO THE QUANTITATIVE TRAITS BY LEVERAGING LONGITUDINAL DATA FROM AN EHR. Clinical laboratory measurements 17,347 European ancestry individuals 17,348 European ancestry individuals Illumina [629274] 8 alkaline phosphatase measurement, calcium measurement, hemoglobin measurement, clinical laboratory measurement, mean corpuscular hemoglobin, glucose measurement, erythrocyte measurement, bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004533, http://www.ebi.ac.uk/efo/EFO_0004838, http://www.ebi.ac.uk/efo/EFO_0004509, http://www.ebi.ac.uk/efo/EFO_0004297, http://www.ebi.ac.uk/efo/EFO_0004527, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0005047, http://www.ebi.ac.uk/efo/EFO_0004570 GCST003540 Genome-wide genotyping array 17347 2017-04-21 27915449 Corre T 2016-12-03 Pflugers Arch www.ncbi.nlm.nih.gov/pubmed/27915449 Common variants in CLDN14 are associated with differential excretion of magnesium over calcium in urine. Urinary electrolytes (magnesium/calcium ratio) 7,498 European ancestry individuals, 1,541 Val Borbera (founder/genetic isolated) individuals, 281 Carlantino (founder/genetic isolated) individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 3 magnesium:calcium ratio http://www.ebi.ac.uk/efo/EFO_0007903 GCST003929 Genome-wide genotyping array 9320 2017-05-11 27941131 Feenstra B 2016-12-09 J Med Genet www.ncbi.nlm.nih.gov/pubmed/27941131 Genome-wide association study identifies variants in HORMAD2 associated with tonsillectomy. Tonsillectomy 1,464 Northwestern European ancestry cases and 12,019 Northwestern European ancestry controls. 1,575 Northwestern European ancestry cases and 1,367 Northwestern European ancestry controls. Illumina [7855469] (imputed) 1 tonsillectomy risk measurement http://www.ebi.ac.uk/efo/EFO_0007924 GCST003974 Genome-wide genotyping array 13483 2016-12-13 26993346 Schott JM 2016-03-15 Alzheimers Dement www.ncbi.nlm.nih.gov/pubmed/26993346 Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease. Posterior cortical atrophy and Alzheimer's disease 293 cases, 10,547 healthy controls NA Illumina [~ 5900000] (imputed) 18 Alzheimer's disease, Posterior cortical atrophy http://www.ebi.ac.uk/efo/EFO_0000249, http://www.orpha.net/ORDO/Orphanet_54247 GCST003452 Genome-wide genotyping array 10840 2017-02-24 26997408 Demirkan A 2016-03-21 Psychol Med www.ncbi.nlm.nih.gov/pubmed/26997408 Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies. Depressive symptoms measurement (somatic complaints domain) 1,107 Erasmus Rucphen (founder/genetic isolate) individuals, 31,421 European ancestry individuals 6,813 European ancestry individuals Affymetrix, Illumina [at least 1069063] (imputed) 1 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST003667 Genome-wide genotyping array 32528 2017-02-24 26997408 Demirkan A 2016-03-21 Psychol Med www.ncbi.nlm.nih.gov/pubmed/26997408 Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies. Depressive symptoms measurement (lack of negative affect domain) 1,107 Erasmus Rucphen (founder/genetic isolate) individuals, 31,421 European ancestry individuals 6,813 European ancestry individuals Affymetrix, Illumina [at least 1069063] (imputed) 0 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST003669 Genome-wide genotyping array 32528 2017-02-24 26997408 Demirkan A 2016-03-21 Psychol Med www.ncbi.nlm.nih.gov/pubmed/26997408 Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies. Depressive symptoms measurement (lack of positive affect domain) 1,107 Erasmus Rucphen (founder/genetic isolate) individuals, 31,421 European ancestry individuals 6,813 European ancestry individuals Affymetrix, Illumina [at least 1069063] (imputed) 0 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST003668 Genome-wide genotyping array 32528 2016-12-13 27005419 Borne Y 2016-03-22 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/27005419 Genome wide association study identifies two loci associated with cadmium in erythrocytes among never-smokers. Erythrocyte cadmium concentration 2,704 ever-smoker individuals, 1,728 never-smoker individuals NA Illumina [658884] 5 erythrocyte cadmium measurement http://www.ebi.ac.uk/efo/EFO_0007807 GCST003449 Genome-wide genotyping array 4432 2016-12-13 27005419 Borne Y 2016-03-22 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/27005419 Genome wide association study identifies two loci associated with cadmium in erythrocytes among never-smokers. Erythrocyte cadmium concentration in never smokers 1,728 individuals NA Illumina [658884] 7 erythrocyte cadmium measurement http://www.ebi.ac.uk/efo/EFO_0007807 GCST003448 Genome-wide genotyping array 1728 2016-07-20 26219847 Adams HH 2015-07-28 J Gerontol A Biol Sci Med Sci www.ncbi.nlm.nih.gov/pubmed/26219847 Heritability and Genome-Wide Association Analyses of Human Gait Suggest Contribution of Common Variants. Gait variability 2,946 individuals NA Illumina [6200000] (imputed) 3 gait measurement http://www.ebi.ac.uk/efo/EFO_0007680 GCST003056 Genome-wide genotyping array 2946 2016-07-20 26219847 Adams HH 2015-07-28 J Gerontol A Biol Sci Med Sci www.ncbi.nlm.nih.gov/pubmed/26219847 Heritability and Genome-Wide Association Analyses of Human Gait Suggest Contribution of Common Variants. Gait rhythm 2,946 individuals NA Illumina [6200000] (imputed) 5 gait measurement http://www.ebi.ac.uk/efo/EFO_0007680 GCST003054 Genome-wide genotyping array 2946 2016-07-20 26219847 Adams HH 2015-07-28 J Gerontol A Biol Sci Med Sci www.ncbi.nlm.nih.gov/pubmed/26219847 Heritability and Genome-Wide Association Analyses of Human Gait Suggest Contribution of Common Variants. Tandem gait 2,946 individuals NA Illumina [6200000] (imputed) 5 gait measurement http://www.ebi.ac.uk/efo/EFO_0007680 GCST003055 Genome-wide genotyping array 2946 2017-04-05 27922604 Yu H 2016-12-06 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/27922604 Common variants on 2p16.1, 6p22.1 and 10q24.32 are associated with schizophrenia in Han Chinese population. Schizophrenia 4,384 Han Chinese ancestry cases and 5,770 Han Chinese ancestry controls 4,339 Han Chinese ancestry cases and 7,043 Han Chinese ancestry controls Illumina [at least 473583] (imputed) 9 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST003880 Genome-wide genotyping array 10154 2017-02-27 27490719 Bacelis J 2016-08-04 PLoS One www.ncbi.nlm.nih.gov/pubmed/27490719 Literature-Informed Analysis of a Genome-Wide Association Study of Gestational Age in Norwegian Women and Children Suggests Involvement of Inflammatory Pathways. Gestational age at birth (maternal effect) 1,743 Norwegian ancestry mothers NA NR [525577] 2 gestational age, birth measurement http://www.ebi.ac.uk/efo/EFO_0005112, http://www.ebi.ac.uk/efo/EFO_0006921 GCST003688 Genome-wide genotyping array 1743 2017-02-27 27490719 Bacelis J 2016-08-04 PLoS One www.ncbi.nlm.nih.gov/pubmed/27490719 Literature-Informed Analysis of a Genome-Wide Association Study of Gestational Age in Norwegian Women and Children Suggests Involvement of Inflammatory Pathways. Gestational age at birth in labor-initiated deliveries (child effect) 884 Norwegian ancestry children NA NR [525577] 12 gestational age http://www.ebi.ac.uk/efo/EFO_0005112 GCST003687 Genome-wide genotyping array 884 2017-02-27 27490719 Bacelis J 2016-08-04 PLoS One www.ncbi.nlm.nih.gov/pubmed/27490719 Literature-Informed Analysis of a Genome-Wide Association Study of Gestational Age in Norwegian Women and Children Suggests Involvement of Inflammatory Pathways. Gestational age at birth in premature rupture of membrane-initiated deliveries (child effect) 225 Norwegian ancestry children NA NR [525577] 8 gestational age http://www.ebi.ac.uk/efo/EFO_0005112 GCST003689 Genome-wide genotyping array 225 2017-02-27 27490719 Bacelis J 2016-08-04 PLoS One www.ncbi.nlm.nih.gov/pubmed/27490719 Literature-Informed Analysis of a Genome-Wide Association Study of Gestational Age in Norwegian Women and Children Suggests Involvement of Inflammatory Pathways. Gestational age at birth in labor-initiated deliveries (maternal effect) 1,407 Norwegian ancestry mothers NA NR [525577] 2 gestational age http://www.ebi.ac.uk/efo/EFO_0005112 GCST003684 Genome-wide genotyping array 1407 2017-02-27 27490719 Bacelis J 2016-08-04 PLoS One www.ncbi.nlm.nih.gov/pubmed/27490719 Literature-Informed Analysis of a Genome-Wide Association Study of Gestational Age in Norwegian Women and Children Suggests Involvement of Inflammatory Pathways. Gestational age at birth in premature rupture of membrane-initiated deliveries (maternal effect) 336 Norwegian ancestry mothers NA NR [525577] 8 gestational age http://www.ebi.ac.uk/efo/EFO_0005112 GCST003685 Genome-wide genotyping array 336 2017-02-27 27490719 Bacelis J 2016-08-04 PLoS One www.ncbi.nlm.nih.gov/pubmed/27490719 Literature-Informed Analysis of a Genome-Wide Association Study of Gestational Age in Norwegian Women and Children Suggests Involvement of Inflammatory Pathways. Gestational age at birth (child effect) 1,109 Norwegian ancestry children NA NR [525577] 13 gestational age, birth measurement http://www.ebi.ac.uk/efo/EFO_0005112, http://www.ebi.ac.uk/efo/EFO_0006921 GCST003686 Genome-wide genotyping array 1109 2017-05-12 27911795 Schumann G 2016-11-28 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/27911795 KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference. Alcohol consumption up to 70,460 European ancestry drinker individuals up to 35,438 European ancestry drinker individuals Affymetrix, Illumina, Perlegen [at least 316407] (imputed) 3 alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0007878 GCST004026 Genome-wide genotyping array 70460 2017-05-12 27911795 Schumann G 2016-11-28 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/27911795 KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference. Alcohol consumption (heavy vs. light/non-drinkers) up to 74,711 European ancestry heavy and light/non-drinker individuals up to 31,021 European ancestry heavy and light/non-drinker individuals Affymetrix, Illumina, Perlegen [at least 316407] (imputed) 2 alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0007878 GCST004027 Genome-wide genotyping array 74711 2017-05-12 27918536 Lo MT 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918536 Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders. Agreeableness 76,551 European ancestry individuals NA Affymetrix, Illumina [2165398] (imputed) 0 agreeableness measurement http://www.ebi.ac.uk/efo/EFO_0007915 GCST004013 Genome-wide genotyping array 76551 2017-05-12 27918536 Lo MT 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918536 Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders. Conscientiousness 76,551 European ancestry individuals 46,581 European ancestry individuals Affymetrix, Illumina [2166809] (imputed) 1 conscientiousness measurement http://www.ebi.ac.uk/efo/EFO_0007912 GCST004014 Genome-wide genotyping array 76551 2017-05-12 27918536 Lo MT 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918536 Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders. Extraversion 122,886 European ancestry individuals 46,621 European ancestry individuals Affymetrix, Illumina [6343667] (imputed) 5 extraversion http://www.ebi.ac.uk/efo/EFO_0004317 GCST004015 Genome-wide genotyping array 122886 2017-05-12 27918536 Lo MT 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918536 Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders. Neuroticism 122,867 European ancestry individuals 137,994 European ancestry individuals Affymetrix, Illumina [6337541] (imputed) 2 neuroticism measurement http://www.ebi.ac.uk/efo/EFO_0007660 GCST004017 Genome-wide genotyping array 122867 2017-05-12 27918536 Lo MT 2016-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27918536 Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders. Openness 76,581 European ancestry individuals NA Affymetrix, Illumina [2167320] (imputed) 0 openness measurement http://www.ebi.ac.uk/efo/EFO_0007914 GCST004016 Genome-wide genotyping array 76581 2017-02-19 27399966 Morris DL 2016-07-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27399966 Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus. Systemic lupus erythematosus 1,659 Chinese ancestry cases, 3,398 Chinese ancestry controls, 4,036 European ancestry cases, 6,959 European ancestry controls 3,043 Chinese ancestry cases, 5,074 Chinese ancestry controls, 2,643 European ancestry cases, 9,032 European ancestry controls NR [6344733] (imputed) 74 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST003622 Genome-wide genotyping array 16052 2017-01-27 27386562 Andlauer TF 2016-06-17 Sci Adv www.ncbi.nlm.nih.gov/pubmed/27386562 Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation. Multiple sclerosis 4,888 German ancestry cases, 10,395 German ancestry controls 2,903 Sardinian ancestry cases, 3,323 Sardinian ancestry controls Illumina [at least 8143088] (imputed) 16 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST003566 Genome-wide genotyping array 15283 2017-02-24 27397699 Pei YF 2016-07-07 Bone www.ncbi.nlm.nih.gov/pubmed/27397699 Genome-wide association meta-analyses identified 1q43 and 2q32.2 for hip Ward's triangle areal bone mineral density. Bone mineral density (Ward's triangle area) 4,305 European ancestry individuals,1,579 Chinese Han ancestry individuals, 845 African-American individuals, 446 Hispanic individuals NA Affymetrix, Illumina [at least 9551331] (imputed) 18 femoral neck bone mineral density http://www.ebi.ac.uk/efo/EFO_0007785 GCST003654 Genome-wide genotyping array 7175 2016-12-13 27023328 Kulkarni D 2016-03-29 Pharmacogenomics www.ncbi.nlm.nih.gov/pubmed/27023328 Pyrexia in dabrafenib-treated melanoma patients is not associated with common genetic variation or HLA polymorphisms. Adverse response to dabrafenib or dabrafenib-trametinib treatment in melanoma (pyrexia) 218 European ancestry cases with pyrexia, 361 European ancestry exposed cases without pyrexia NA Affymetrix, Illumina [6000000] (imputed) 0 response to trametinib, Fever, response to dabrafenib http://www.ebi.ac.uk/efo/EFO_0007816, http://purl.obolibrary.org/obo/HP_0001945, http://www.ebi.ac.uk/efo/EFO_0007815 GCST003456 Genome-wide genotyping array 579 2017-03-31 27117709 Couch FJ 2016-04-27 Nat Commun www.ncbi.nlm.nih.gov/pubmed/27117709 Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer. Breast cancer 4,939 European ancestry estrogen receptor-negative cases, 14,352 European ancestry controls 7,333 European ancestry estrogen receptor-negative cases, 7,797 European ancestry BRCA1 mutation carrier cases, 7,455 European ancestry BRCA1 mutation carrier controls, 42,468 European ancestry controls Illumina [10909381] (imputed) 31 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST003845 Genome-wide genotyping array 19291 2017-03-31 27117709 Couch FJ 2016-04-27 Nat Commun www.ncbi.nlm.nih.gov/pubmed/27117709 Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer. Breast cancer (estrogen-receptor negative) 4,939 European ancestry cases, 14,352 European ancestry controls 7,333 European ancestry cases, 42,468 European ancestry controls Illumina [10909381] (imputed) 25 estrogen-receptor negative breast cancer http://www.ebi.ac.uk/efo/EFO_1000650 GCST003842 Genome-wide genotyping array 19291 2017-04-10 27957625 Bacchelli E 2016-12-13 J Headache Pain www.ncbi.nlm.nih.gov/pubmed/27957625 A genome-wide analysis in cluster headache points to neprilysin and PACAP receptor gene variants. Cluster headache 99 Italian ancestry cases, 359 Italian ancestry smoker controls NA Illumina [290505] 2 smoking status measurement, Cluster headache http://www.ebi.ac.uk/efo/EFO_0006527, http://purl.obolibrary.org/obo/HP_0012199 GCST003900 Genome-wide genotyping array 458 2017-04-05 27899403 Jones GT 2016-11-29 Circ Res www.ncbi.nlm.nih.gov/pubmed/27899403 Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci. Abdominal aortic aneurysm 4,972 European ancestry cases, 99,858 European ancestry controls 2,482 European ancestry cases, 2,750 cases, 2,645 European ancestry controls, 5,263 controls Affymetrix, Illumina [5363770] (imputed) 12 Abdominal Aortic Aneurysm http://www.ebi.ac.uk/efo/EFO_0004214 GCST003877 Genome-wide genotyping array 104830 2016-12-13 27067015 Smith DJ 2016-04-12 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/27067015 Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci. Neuroticism 91,370 European ancestry individuals, 15,346 individuals NA Affymetrix [7207648] (imputed) 13 neuroticism measurement http://www.ebi.ac.uk/efo/EFO_0007660 GCST003447 Genome-wide genotyping array 106716 2017-03-22 27798627 Barban N 2016-10-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27798627 Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Number of children ever born 225,230 European ancestry women, 103,909 European ancestry men NA NR [2400000] (imputed) 2 number of children ever born measurement http://www.ebi.ac.uk/efo/EFO_0009102 GCST003796 Genome-wide genotyping array 329139 2017-03-22 27798627 Barban N 2016-10-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27798627 Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Age at first birth 189,656 European ancestry women, 48,408 European ancestry men NA Illumina [2400000] (imputed) 10 age at first birth measurement http://www.ebi.ac.uk/efo/EFO_0009101 GCST003795 Genome-wide genotyping array 238064 2018-08-07 27798627 Barban N 2016-10-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27798627 Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Number of children ever born 103,909 European ancestry men NA NR [2400000] (imputed) 2 number of children ever born measurement http://www.ebi.ac.uk/efo/EFO_0009102 GCST006046 Genome-wide genotyping array 103909 2018-08-07 27798627 Barban N 2016-10-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27798627 Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Number of children ever born 225,230 European ancestry women NA NR [2400000] (imputed) 1 number of children ever born measurement http://www.ebi.ac.uk/efo/EFO_0009102 GCST006047 Genome-wide genotyping array 225230 2018-08-06 27798627 Barban N 2016-10-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27798627 Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Age at first birth 48,408 European ancestry men NA Illumina [2400000] (imputed) 2 age at first birth measurement http://www.ebi.ac.uk/efo/EFO_0009101 GCST006044 Genome-wide genotyping array 48408 2018-08-06 27798627 Barban N 2016-10-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27798627 Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Age at first birth 189,656 European ancestry women NA Illumina [2400000] (imputed) 10 age at first birth measurement http://www.ebi.ac.uk/efo/EFO_0009101 GCST006045 Genome-wide genotyping array 189656 2017-02-25 27286809 Ligthart S 2016-06-10 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/27286809 Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation. C-reactive protein levels or triglyceride levels (pleiotropy) 65,000 individuals (C-reactive protein), 96,598 individuals (triglycerides) NA NR [25015711] (imputed) 21 triglyceride measurement, C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0004458 GCST003681 Genome-wide genotyping array 161598 2017-02-25 27286809 Ligthart S 2016-06-10 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/27286809 Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation. C-reactive protein levels or HDL-cholesterol levels (pleiotropy) 65,000 individuals (C-reactive protein), 99,900 individuals (HDL-cholesterol) NA NR [2501543] (imputed) 20 C-reactive protein measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004458, http://www.ebi.ac.uk/efo/EFO_0004612 GCST003680 Genome-wide genotyping array 164900 2017-02-25 27286809 Ligthart S 2016-06-10 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/27286809 Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation. C-reactive protein levels or LDL-cholesterol levels (pleiotropy) 65,000 individuals (C-reactive protein), 95,454 individuals (LDL-cholesterol) NA NR [2501749] (imputed) 21 low density lipoprotein cholesterol measurement, C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004611, http://www.ebi.ac.uk/efo/EFO_0004458 GCST003679 Genome-wide genotyping array 160454 2017-02-25 27286809 Ligthart S 2016-06-10 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/27286809 Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation. C-reactive protein levels or total cholesterol levels (pleiotropy) 65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol) NA NR [2501549] (imputed) 20 total cholesterol measurement, C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0004458 GCST003678 Genome-wide genotyping array 165184 2016-12-11 27047539 Fridley BL 2016-03-22 Front Genet www.ncbi.nlm.nih.gov/pubmed/27047539 Genome-Wide Study of Response to Platinum, Taxane, and Combination Therapy in Ovarian Cancer: In vitro Phenotypes, Inherited Variation, and Disease Recurrence. Response to carboplatin in ovarian cancer (MTT IC50) 74 lymphoblastoid cell lines NA Illumina [6243550] (imputed) 2 response to platinum based chemotherapy, cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0004647, http://www.ebi.ac.uk/efo/EFO_0006952 GCST003440 Genome-wide genotyping array 74 2016-12-11 27047539 Fridley BL 2016-03-22 Front Genet www.ncbi.nlm.nih.gov/pubmed/27047539 Genome-Wide Study of Response to Platinum, Taxane, and Combination Therapy in Ovarian Cancer: In vitro Phenotypes, Inherited Variation, and Disease Recurrence. Response to carboplatin and paclitaxel in ovarian cancer (Caspase 3/7 EC50) 74 lymphoblastoid cell lines NA Illumina [6243550] (imputed) 3 response to platinum based chemotherapy, cytotoxicity measurement, response to paclitaxel http://www.ebi.ac.uk/efo/EFO_0004647, http://www.ebi.ac.uk/efo/EFO_0006952, http://purl.obolibrary.org/obo/GO_1901555 GCST003443 Genome-wide genotyping array 74 2016-12-11 27047539 Fridley BL 2016-03-22 Front Genet www.ncbi.nlm.nih.gov/pubmed/27047539 Genome-Wide Study of Response to Platinum, Taxane, and Combination Therapy in Ovarian Cancer: In vitro Phenotypes, Inherited Variation, and Disease Recurrence. Response to paclitaxel in ovarian cancer (Caspase 3/7 EC50) 74 lymphoblastoid cell lines NA Illumina [6243550] (imputed) 2 response to platinum based chemotherapy, cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0004647, http://www.ebi.ac.uk/efo/EFO_0006952 GCST003439 Genome-wide genotyping array 74 2016-12-11 27047539 Fridley BL 2016-03-22 Front Genet www.ncbi.nlm.nih.gov/pubmed/27047539 Genome-Wide Study of Response to Platinum, Taxane, and Combination Therapy in Ovarian Cancer: In vitro Phenotypes, Inherited Variation, and Disease Recurrence. Response to carboplatin in ovarian cancer (Caspase 3/7 EC50) 74 lymphoblastoid cell lines NA Illumina [6243550] (imputed) 0 response to platinum based chemotherapy, cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0004647, http://www.ebi.ac.uk/efo/EFO_0006952 GCST003442 Genome-wide genotyping array 74 2016-12-11 27047539 Fridley BL 2016-03-22 Front Genet www.ncbi.nlm.nih.gov/pubmed/27047539 Genome-Wide Study of Response to Platinum, Taxane, and Combination Therapy in Ovarian Cancer: In vitro Phenotypes, Inherited Variation, and Disease Recurrence. Response to paclitaxel in ovarian cancer (MTT IC50) 74 lymphoblastoid cell lines NA Illumina [6243550] (imputed) 1 cytotoxicity measurement, response to paclitaxel http://www.ebi.ac.uk/efo/EFO_0006952, http://purl.obolibrary.org/obo/GO_1901555 GCST003441 Genome-wide genotyping array 74 2016-12-11 27047539 Fridley BL 2016-03-22 Front Genet www.ncbi.nlm.nih.gov/pubmed/27047539 Genome-Wide Study of Response to Platinum, Taxane, and Combination Therapy in Ovarian Cancer: In vitro Phenotypes, Inherited Variation, and Disease Recurrence. Response to carboplatin and paclitaxel in ovarian cancer (MTT IC50) 74 lymphoblastoid cell lines NA Illumina [6243550] (imputed) 2 response to platinum based chemotherapy, cytotoxicity measurement, response to paclitaxel http://www.ebi.ac.uk/efo/EFO_0004647, http://www.ebi.ac.uk/efo/EFO_0006952, http://purl.obolibrary.org/obo/GO_1901555 GCST003444 Genome-wide genotyping array 74 2017-05-11 27992416 Lane JM 2016-12-19 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27992416 Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits. Excessive daytime sleepiness 111,648 European ancestry individuals NA Affymetrix [up to 73355677] (imputed) 13 excessive daytime sleepiness measurement http://www.ebi.ac.uk/efo/EFO_0007875 GCST003979 Genome-wide genotyping array 111648 2017-05-11 27992416 Lane JM 2016-12-19 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27992416 Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits. Sleep duration 111,975 European ancestry individuals NA Affymetrix [up to 73355677] (imputed) 8 sleep duration http://www.ebi.ac.uk/efo/EFO_0005271 GCST003980 Genome-wide genotyping array 111975 2017-05-11 27992416 Lane JM 2016-12-19 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27992416 Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits. Sleep traits (multi-trait analysis) At least 112,586 European ancestry individuals NA Affymetrix [up to 73355677] (imputed) 6 sleep duration, circadian rhythm, excessive daytime sleepiness measurement, insomnia measurement http://www.ebi.ac.uk/efo/EFO_0005271, http://www.ebi.ac.uk/efo/EFO_0004354, http://www.ebi.ac.uk/efo/EFO_0007875, http://www.ebi.ac.uk/efo/EFO_0007876 GCST003982 Genome-wide genotyping array 112586 2017-05-11 27992416 Lane JM 2016-12-19 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27992416 Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits. Insomnia up to 12,674 European ancestry male cases, up to 19,481 European ancestry female cases, up to 16,009 European ancestry male controls, up to 10,964 European ancestry female controls, NA Affymetrix [up to 73355677] (imputed) 8 insomnia measurement http://www.ebi.ac.uk/efo/EFO_0007876 GCST003981 Genome-wide genotyping array 59128 2017-05-26 28223688 Bjornsdottir G 2017-02-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28223688 Sequence variant at 8q24.21 associates with sciatica caused by lumbar disc herniation. Sciatica caused by lumbar disc herniation (treated with microdiscectomy) 3,097 Icelandic ancestry cases, 1,651 non-array typed, familial imputed Icelandic ancestry cases, 132,966 Icelandic ancestry controls, 149,624 non-array typed, familial imputed Icelandic ancestry controls NR Illumina [21568490] (imputed) 1 lumbar disc herniation, Sciatica, LDH-related sciatica symptom severity measurement http://www.ebi.ac.uk/efo/EFO_1002005, http://purl.obolibrary.org/obo/HP_0011868, http://www.ebi.ac.uk/efo/EFO_0007941 GCST004098 Genome-wide genotyping array 287338 2017-03-24 27622933 Li QS 2016-09-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/27622933 Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response. Response to selective serotonin reuptake inhibitors in depression 6,348 European ancestry responder cases, 3,340 European ancestry non-responder cases NA Illumina [~ 12000000] (imputed) 5 response to selective serotonin reuptake inhibitor http://www.ebi.ac.uk/efo/EFO_0005658 GCST003801 Genome-wide genotyping array 9688 2017-03-24 27622933 Li QS 2016-09-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/27622933 Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response. Response to citalopram or escitalopram in depression 2,963 European ancestry responder cases, 2,005 European ancestry non-responder cases NA Illumina [~ 12000000] (imputed) 7 response to escitalopram, response to citalopram http://www.ebi.ac.uk/efo/EFO_0007871, http://www.ebi.ac.uk/efo/EFO_0006329 GCST003802 Genome-wide genotyping array 4968 2017-03-24 27622933 Li QS 2016-09-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/27622933 Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response. Response to antidepressants in depression 7,795 European ancestry responder cases, 1,311 European ancestry non-responder cases NA Illumina [~ 12000000] (imputed) 5 response to antidepressant http://purl.obolibrary.org/obo/GO_0036276 GCST003803 Genome-wide genotyping array 9106 2017-03-24 27622933 Li QS 2016-09-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/27622933 Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response. Non-response to bupropion and depression 1,861 European ancestry non-responder cases, 192,070 European ancestry healthy controls NA Illumina [~ 12000000] (imputed) 6 unipolar depression, response to bupropion, mood disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0006326, http://www.ebi.ac.uk/efo/EFO_0004247 GCST003804 Genome-wide genotyping array 193931 2017-03-24 27622933 Li QS 2016-09-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/27622933 Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response. Response to bupropion and depression 2,675 European ancestry responder cases, 191,986 European ancestry healthy controls NA Illumina [~ 12000000] (imputed) 5 unipolar depression, response to bupropion, mood disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0006326, http://www.ebi.ac.uk/efo/EFO_0004247 GCST003806 Genome-wide genotyping array 194661 2017-03-24 27622933 Li QS 2016-09-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/27622933 Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response. Response to selective serotonin reuptake inhibitors and depression 6,348 European ancestry responder cases, 191,357 European ancestry healthy controls NA Illumina [~ 12000000] (imputed) 5 unipolar depression, response to selective serotonin reuptake inhibitor, mood disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0005658, http://www.ebi.ac.uk/efo/EFO_0004247 GCST003809 Genome-wide genotyping array 197705 2017-03-24 27622933 Li QS 2016-09-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/27622933 Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response. Non-response to citalopram or escitalopram and depression 2,005 European ancestry non-responder cases, 192,083 European ancestry healthy controls NA Illumina [~ 12000000] (imputed) 5 unipolar depression, response to escitalopram, response to citalopram, mood disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0007871, http://www.ebi.ac.uk/efo/EFO_0006329, http://www.ebi.ac.uk/efo/EFO_0004247 GCST003810 Genome-wide genotyping array 194088 2017-03-24 27622933 Li QS 2016-09-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/27622933 Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response. Response to citalopram or escitalopram and depression 2,963 European ancestry responder cases, 191,936 European ancestry healthy controls NA Illumina [~ 12000000] (imputed) 5 unipolar depression, response to escitalopram, response to citalopram, mood disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0007871, http://www.ebi.ac.uk/efo/EFO_0006329, http://www.ebi.ac.uk/efo/EFO_0004247 GCST003811 Genome-wide genotyping array 194899 2017-03-24 27622933 Li QS 2016-09-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/27622933 Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response. Non-response to antidepressants and depression 1,311 European ancestry non-responder cases, 192,178 European ancestry healthy controls NA Illumina [~ 12000000] (imputed) 5 unipolar depression, mood disorder, response to antidepressant http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0004247, http://purl.obolibrary.org/obo/GO_0036276 GCST003812 Genome-wide genotyping array 193489 2017-03-24 27622933 Li QS 2016-09-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/27622933 Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response. Non-response to selective serotonin reuptake inhibitors and depression 3,340 European ancestry non-responder cases, 191,882 European ancestry healthy controls NA Illumina [~ 12000000] (imputed) 5 unipolar depression, response to selective serotonin reuptake inhibitor, mood disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0005658, http://www.ebi.ac.uk/efo/EFO_0004247 GCST003808 Genome-wide genotyping array 195222 2017-03-24 27622933 Li QS 2016-09-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/27622933 Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response. Response to antidepressants and depression 7,795 European ancestry responder cases, 191,173 European ancestry healthy controls NA Illumina [~ 12000000] (imputed) 5 unipolar depression, mood disorder, response to antidepressant http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0004247, http://purl.obolibrary.org/obo/GO_0036276 GCST003813 Genome-wide genotyping array 198968 2017-03-24 27622933 Li QS 2016-09-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/27622933 Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response. Response to bupropion in depression 2,675 European ancestry responder cases, 1,861 European ancestry non-responder cases NA Illumina [~ 12000000] (imputed) 5 response to bupropion http://www.ebi.ac.uk/efo/EFO_0006326 GCST003800 Genome-wide genotyping array 4536 2017-06-13 28232668 Yu Y 2017-02-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28232668 Genome-wide analyses of non-syndromic cleft lip with palate identify 14 novel loci and genetic heterogeneity. Nonsyndromic cleft lip with cleft palate 2,033 Han Chinese ancestry cases, 4,051 Han Chinese ancestry controls 1,346 Han Chinese ancestry cases, 4,542 Han Chinese ancestry controls Illumina [803202] 56 Cleft palate, cleft lip http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959 GCST004166 Genome-wide genotyping array 6084 2018-09-14 27618452 Ehret GB 2016-09-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27618452 The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Diastolic blood pressure up to 201,529 European ancestry individuals up to 140,886 European ancestry individuals Affymetrix, Illumina, Perlegen [128272] 57 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST006258 Targeted genotyping array [CardioMetaboChip] 201529 2018-09-14 27618452 Ehret GB 2016-09-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27618452 The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Systolic blood pressure up to 201,529 European ancestry individuals up to 140,886 European ancestry individuals Affymetrix, Illumina, Perlegen [128272] 62 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST006259 Targeted genotyping array [CardioMetaboChip] 201529 2017-06-15 28193307 Lin BD 2017-02-14 Twin Res Hum Genet www.ncbi.nlm.nih.gov/pubmed/28193307 Heritability and GWAS Studies for Monocyte-Lymphocyte Ratio. Monocyte-lymphocyte ratio 5,892 Dutch ancestry individuals NA Affymetrix, Illumina, Perlegen [5987253] (imputed) 3 monocyte:lymphocyte ratio http://www.ebi.ac.uk/efo/EFO_0007956 GCST004170 Genome-wide genotyping array 5892 2017-06-12 28193307 Lin BD 2017-02-14 Twin Res Hum Genet www.ncbi.nlm.nih.gov/pubmed/28193307 Heritability and GWAS Studies for Monocyte-Lymphocyte Ratio. Monocyte count 5,892 Dutch ancestry individuals NA Affymetrix, Illumina, Perlegen [5987253] (imputed) 5 monocyte count http://www.ebi.ac.uk/efo/EFO_0005091 GCST004164 Genome-wide genotyping array 5892 2017-03-20 27629369 Gao J 2016-09-15 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/27629369 Genome-Wide Association Study of Loneliness Demonstrates a Role for Common Variation. Loneliness (multivariate analysis) 8,490 European ancestry individuals, 1,228 African American individuals, 867 Hispanic American individuals, 175 individuals NA Illumina [7205781] (imputed) 19 loneliness measurement http://www.ebi.ac.uk/efo/EFO_0007865 GCST003773 Genome-wide genotyping array 10760 2017-03-20 27629369 Gao J 2016-09-15 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/27629369 Genome-Wide Association Study of Loneliness Demonstrates a Role for Common Variation. Loneliness 2,075 European ancestry cases, 3,875 European ancestry controls, 427 African American cases, 398 African American controls, 294 Hispanic cases, 327 Hispanic controls, 57 cases, 73 controls NA Illumina [7176022] (imputed) 22 loneliness measurement http://www.ebi.ac.uk/efo/EFO_0007865 GCST003771 Genome-wide genotyping array 7526 2017-03-20 27629369 Gao J 2016-09-15 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/27629369 Genome-Wide Association Study of Loneliness Demonstrates a Role for Common Variation. Loneliness (linear analysis) 8,490 European ancestry individuals, 1,228 African American individuals, 867 Hispanic American individuals, 175 individuals NA Illumina [7205781] (imputed) 18 loneliness measurement http://www.ebi.ac.uk/efo/EFO_0007865 GCST003772 Genome-wide genotyping array 10760 2016-12-06 27207650 Schmit SL 2016-04-18 Carcinogenesis www.ncbi.nlm.nih.gov/pubmed/27207650 Genome-wide association study of colorectal cancer in Hispanics. Colorectal cancer 1,611 Hispanic cases, 4,330 Hispanic controls NA Illumina [9875636] (imputed) 7 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST003420 Genome-wide genotyping array 5941 2017-01-27 27098658 Muller-Calleja N 2016-04-21 Thromb Haemost www.ncbi.nlm.nih.gov/pubmed/27098658 Antiphospholipid antibodies in a large population-based cohort: genome-wide associations and effects on monocyte gene expression. Presence of antiphospholipid antibodies 4,163 German ancestry individuals NA Affymetrix [at least 662405] 12 antiphospholipid antibody measurement http://www.ebi.ac.uk/efo/EFO_0005200 GCST003563 Genome-wide genotyping array 4163 2017-05-23 28247064 Deming Y 2017-02-28 Acta Neuropathol www.ncbi.nlm.nih.gov/pubmed/28247064 Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers. Cerebrospinal fluid AB1-42 levels 3,146 individuals NA Illumina [7358575] (imputed) 16 beta-amyloid 1-42 measurement http://www.ebi.ac.uk/efo/EFO_0004670 GCST004069 Genome-wide genotyping array 3146 2017-05-23 28247064 Deming Y 2017-02-28 Acta Neuropathol www.ncbi.nlm.nih.gov/pubmed/28247064 Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers. Cerebrospinal P-tau181p levels 3,146 individuals NA Illumina [7358575] (imputed) 22 p-tau measurement http://www.ebi.ac.uk/efo/EFO_0004763 GCST004070 Genome-wide genotyping array 3146 2017-05-23 28247064 Deming Y 2017-02-28 Acta Neuropathol www.ncbi.nlm.nih.gov/pubmed/28247064 Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers. Cerebrospinal T-tau levels 3,146 individuals NA Illumina [7358575] (imputed) 19 t-tau measurement http://www.ebi.ac.uk/efo/EFO_0004760 GCST004071 Genome-wide genotyping array 3146 2017-04-21 27899376 Nakayama A 2016-11-29 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/27899376 GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes. Gout 945 Japanese ancestry cases, 1,213 Japanese ancestry controls 1,396 Japanese ancestry cases, 1,268 Japanese ancestry controls, 1,319 European ancestry cases, 514 European ancestry controls, 971 Polynesian ancestry cases, 565 Polynesian ancestry controls Illumina [570442] 11 gout http://www.ebi.ac.uk/efo/EFO_0004274 GCST003925 Genome-wide genotyping array 2158 2017-04-21 27899376 Nakayama A 2016-11-29 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/27899376 GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes. Renal underexcretion gout 619 Japanese ancestry cases, 1,213 Japanese ancestry controls 696 Japanese ancestry cases, 1,268 Japanese ancestry controls Illumina [570442] 8 gout http://www.ebi.ac.uk/efo/EFO_0004274 GCST003926 Genome-wide genotyping array 1832 2017-04-21 27899376 Nakayama A 2016-11-29 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/27899376 GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes. Renal overload gout 560 Japanese ancestry cases, 1,213 Japanese ancestry controls 618 Japanese ancestry cases, 1,268 Japanese ancestry controls Illumina [570442] 5 gout http://www.ebi.ac.uk/efo/EFO_0004274 GCST003924 Genome-wide genotyping array 1773 2017-07-03 28235828 Traglia M 2017-04-03 G3 (Bethesda) www.ncbi.nlm.nih.gov/pubmed/28235828 Independent Maternal and Fetal Genetic Effects on Midgestational Circulating Levels of Environmental Pollutants. Midgestational circulating levels of organochlorine pesticides 329 Hispanic mothers, 273 European ancestry mothers, 122 Asian ancestry mothers, 23 South Asian ancestry mothers, 21 African American mothers, 22 other ancestry mothers NA Affymetrix [629686] 2 gestational serum measurement, organochlorine pesticide measurement http://www.ebi.ac.uk/efo/EFO_0007964, http://www.ebi.ac.uk/efo/EFO_0007960 GCST004281 Genome-wide genotyping array 790 2017-07-03 28235828 Traglia M 2017-04-03 G3 (Bethesda) www.ncbi.nlm.nih.gov/pubmed/28235828 Independent Maternal and Fetal Genetic Effects on Midgestational Circulating Levels of Environmental Pollutants. Midgestational circulating levels of PCBs (fetal genetic effect) 764 fetuses NA Affymetrix [622716] 11 polychlorinated biphenyls measurement, gestational serum measurement, fetal genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0007042, http://www.ebi.ac.uk/efo/EFO_0007964, http://www.ebi.ac.uk/efo/EFO_0007959 GCST004284 Genome-wide genotyping array 764 2017-07-03 28235828 Traglia M 2017-04-03 G3 (Bethesda) www.ncbi.nlm.nih.gov/pubmed/28235828 Independent Maternal and Fetal Genetic Effects on Midgestational Circulating Levels of Environmental Pollutants. Midgestational circulating levels of PBDEs 329 Hispanic mothers, 273 European ancestry mothers, 122 Asian ancestry mothers, 23 South Asian ancestry mothers, 21 African American mothers, 22 other ancestry mothers NA Affymetrix [629686] 9 polybrominated biphenyl measurement, gestational serum measurement, polybrominated diphenyl ether measurement http://www.ebi.ac.uk/efo/EFO_0007961, http://www.ebi.ac.uk/efo/EFO_0007964, http://www.ebi.ac.uk/efo/EFO_0007962 GCST004285 Genome-wide genotyping array 790 2017-07-03 28235828 Traglia M 2017-04-03 G3 (Bethesda) www.ncbi.nlm.nih.gov/pubmed/28235828 Independent Maternal and Fetal Genetic Effects on Midgestational Circulating Levels of Environmental Pollutants. Midgestational circulating levels of PBDEs (fetal genetic effect) 764 fetuses NA Affymetrix [629686] 11 polybrominated biphenyl measurement, gestational serum measurement, fetal genotype effect measurement, polybrominated diphenyl ether measurement http://www.ebi.ac.uk/efo/EFO_0007961, http://www.ebi.ac.uk/efo/EFO_0007964, http://www.ebi.ac.uk/efo/EFO_0007959, http://www.ebi.ac.uk/efo/EFO_0007962 GCST004286 Genome-wide genotyping array 764 2017-07-03 28235828 Traglia M 2017-04-03 G3 (Bethesda) www.ncbi.nlm.nih.gov/pubmed/28235828 Independent Maternal and Fetal Genetic Effects on Midgestational Circulating Levels of Environmental Pollutants. Midgestational circulating levels of organochlorine pesticides (fetal genetic effect) 764 fetuses NA Affymetrix [629686] 0 gestational serum measurement, fetal genotype effect measurement, organochlorine pesticide measurement http://www.ebi.ac.uk/efo/EFO_0007964, http://www.ebi.ac.uk/efo/EFO_0007959, http://www.ebi.ac.uk/efo/EFO_0007960 GCST004282 Genome-wide genotyping array 764 2017-07-03 28235828 Traglia M 2017-04-03 G3 (Bethesda) www.ncbi.nlm.nih.gov/pubmed/28235828 Independent Maternal and Fetal Genetic Effects on Midgestational Circulating Levels of Environmental Pollutants. Midgestational circulating levels of PCBs 329 Hispanic mothers, 273 European ancestry mothers, 122 Asian ancestry mothers, 23 South Asian ancestry mothers, 21 African American mothers, 22 other ancestry mothers NA Affymetrix [629686] 25 polychlorinated biphenyls measurement, gestational serum measurement http://www.ebi.ac.uk/efo/EFO_0007042, http://www.ebi.ac.uk/efo/EFO_0007964 GCST004283 Genome-wide genotyping array 790 2017-03-31 27702941 Cornelis MC 2016-10-03 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/27702941 Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior. Caffeine metabolism (plasma 1,3,7-trimethyluric acid level) 3,562 European ancestry individuals NA Illumina [~ 31000000] (imputed) 0 caffeine metabolite measurement http://www.ebi.ac.uk/efo/EFO_0007872 GCST003850 Genome-wide genotyping array 3562 2017-03-31 27702941 Cornelis MC 2016-10-03 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/27702941 Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior. Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level) 5,353 European ancestry individuals 833 European ancestry individuals Illumina [~ 31000000] (imputed) 2 caffeine metabolite measurement http://www.ebi.ac.uk/efo/EFO_0007872 GCST003847 Genome-wide genotyping array 5353 2017-03-31 27702941 Cornelis MC 2016-10-03 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/27702941 Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior. Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level) 8,911 European ancestry individuals 824 European ancestry individuals Illumina [~ 31000000] (imputed) 1 caffeine metabolite measurement http://www.ebi.ac.uk/efo/EFO_0007872 GCST003849 Genome-wide genotyping array 8911 2017-03-31 27702941 Cornelis MC 2016-10-03 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/27702941 Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior. Caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level) 9,054 European ancestry individuals 822 European ancestry individuals Illumina [~ 31000000] (imputed) 11 caffeine metabolite measurement http://www.ebi.ac.uk/efo/EFO_0007872 GCST003846 Genome-wide genotyping array 9054 2017-03-31 27702941 Cornelis MC 2016-10-03 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/27702941 Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior. Caffeine metabolism (plasma 1,3-dimethylxanthine (theophylline) level) 5,261 European ancestry individuals 826 European ancestry individuals Illumina [~ 31000000] (imputed) 4 caffeine metabolite measurement http://www.ebi.ac.uk/efo/EFO_0007872 GCST003848 Genome-wide genotyping array 5261 2017-03-31 27702941 Cornelis MC 2016-10-03 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/27702941 Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior. Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) 5,323 European ancestry individuals 824 European ancestry individuals Illumina [~ 31000000] (imputed) 31 caffeine metabolite measurement http://www.ebi.ac.uk/efo/EFO_0007872 GCST003851 Genome-wide genotyping array 5323 2017-05-12 27997041 Traylor M 2016-12-20 Ann Neurol www.ncbi.nlm.nih.gov/pubmed/27997041 Genetic variation at 16q24.2 is associated with small vessel stroke. Ischemic stroke 10,210 European ancestry cases, 12,285 European ancestry controls 7,743 European ancestry cases, 17,970 European ancestry controls Affymetrix, Illumina [NR] (imputed) 7 Ischemic stroke http://purl.obolibrary.org/obo/HP_0002140 GCST004023 Genome-wide genotyping array 22495 2017-05-12 27997041 Traylor M 2016-12-20 Ann Neurol www.ncbi.nlm.nih.gov/pubmed/27997041 Genetic variation at 16q24.2 is associated with small vessel stroke. Ischemic stroke (cardioembolic) 1,715 European ancestry cases, 12,285 European ancestry controls 3,101 European ancestry cases, 38,443 European ancestry controls Affymetrix, Illumina [NR] (imputed) 0 cardioembolic stroke http://www.ebi.ac.uk/efo/EFO_1001976 GCST004021 Genome-wide genotyping array 14000 2017-05-12 27997041 Traylor M 2016-12-20 Ann Neurol www.ncbi.nlm.nih.gov/pubmed/27997041 Genetic variation at 16q24.2 is associated with small vessel stroke. Small vessel stroke 2,275 European ancestry cases, 12,285 European ancestry controls 1,928 European ancestry cases, 38,443 European ancestry controls Affymetrix, Illumina [NR] (imputed) 1 small vessel stroke http://www.ebi.ac.uk/efo/EFO_1001504 GCST004020 Genome-wide genotyping array 14560 2017-05-12 27997041 Traylor M 2016-12-20 Ann Neurol www.ncbi.nlm.nih.gov/pubmed/27997041 Genetic variation at 16q24.2 is associated with small vessel stroke. Large artery stroke 1,877 European ancestry cases, 12,285 European ancestry controls 1,130 European ancestry cases, 17,970 European ancestry controls Affymetrix, Illumina [NR] (imputed) 5 large artery stroke http://www.ebi.ac.uk/efo/EFO_0005524 GCST004022 Genome-wide genotyping array 14162 2017-05-22 28095793 Chittoor G 2017-01-17 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/28095793 Genetic variation underlying renal uric acid excretion in Hispanic children: the Viva La Familia Study. Glomerular load of uric acid 768 Hispanic children from 260 families NA Illumina [899892] 1 uric acid measurement http://www.ebi.ac.uk/efo/EFO_0004761 GCST004054 Genome-wide genotyping array 1028 2017-05-22 28095793 Chittoor G 2017-01-17 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/28095793 Genetic variation underlying renal uric acid excretion in Hispanic children: the Viva La Familia Study. Uric acid clearance 768 Hispanic children from 260 families NA Illumina [899892] 3 uric acid measurement http://www.ebi.ac.uk/efo/EFO_0004761 GCST004058 Genome-wide genotyping array 1028 2017-05-22 28095793 Chittoor G 2017-01-17 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/28095793 Genetic variation underlying renal uric acid excretion in Hispanic children: the Viva La Familia Study. Fractional excretion of uric acid 768 Hispanic children from 260 families NA Illumina [899892] 1 uric acid measurement http://www.ebi.ac.uk/efo/EFO_0004761 GCST004055 Genome-wide genotyping array 1028 2017-05-22 28095793 Chittoor G 2017-01-17 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/28095793 Genetic variation underlying renal uric acid excretion in Hispanic children: the Viva La Familia Study. Creatinine clearance 768 Hispanic children from 260 families NA Illumina [899892] 1 creatinine clearance measurement http://www.ebi.ac.uk/efo/EFO_0007934 GCST004057 Genome-wide genotyping array 1028 2017-05-22 28095793 Chittoor G 2017-01-17 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/28095793 Genetic variation underlying renal uric acid excretion in Hispanic children: the Viva La Familia Study. Urinary uric acid to urinary creatinine ratio 768 Hispanic children from 260 families NA Illumina [899892] 2 urinary uric acid to creatinine ratio http://www.ebi.ac.uk/efo/EFO_0007935 GCST004056 Genome-wide genotyping array 1028 2017-10-27 28892062 Akiyama M 2017-09-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28892062 Genome-wide association study identifies 112 new loci for body mass index in the Japanese population. Body mass index up to 72,390 Japanese ancestry women, up to 85,894 Japanese ancestry men up to 10,048 Japanese ancestry women, up to 5,098 Japanese ancestry men, up to 181,999 European ancestry women, up to 140,155 European ancestry controls Illumina [6108953] (imputed) 265 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST004904 Genome-wide genotyping array 158284 2018-07-03 29356057 Du Z 2018-01-21 Prostate www.ncbi.nlm.nih.gov/pubmed/29356057 Genetic risk of prostate cancer in Ugandan men. Prostate cancer 560 Ugandan ancestry cases, 480 Ugandan ancestry controls NA Illumina [17125421] (imputed) 25 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST005786 Genome-wide genotyping array 1040 2018-02-09 29354237 Kim HA 2018-01-01 J Korean Neurosurg Soc www.ncbi.nlm.nih.gov/pubmed/29354237 Novel Genetic Variants Associated with Lumbar Spondylosis in Koreans : A Genome-Wide Association Study. Lumbar spondylosis (disc space narrowing) 228 Korean ancestry cases, 1197 Korean ancestry controls NA Affymetrix [352228] 0 lumbar disc degeneration http://www.ebi.ac.uk/efo/EFO_0004994 GCST005279 Genome-wide genotyping array 1425 2018-02-09 29354237 Kim HA 2018-01-01 J Korean Neurosurg Soc www.ncbi.nlm.nih.gov/pubmed/29354237 Novel Genetic Variants Associated with Lumbar Spondylosis in Koreans : A Genome-Wide Association Study. Lumbar spondylosis (presence and severity of osteophytes) 762 Korean ancestry cases, 664 Korean ancestry controls NA Affymetrix [352228] 0 lumbar disc degeneration http://www.ebi.ac.uk/efo/EFO_0004994 GCST005278 Genome-wide genotyping array 1426 2018-02-09 29354237 Kim HA 2018-01-01 J Korean Neurosurg Soc www.ncbi.nlm.nih.gov/pubmed/29354237 Novel Genetic Variants Associated with Lumbar Spondylosis in Koreans : A Genome-Wide Association Study. Lumbar spondylosis (Kellgren-Lawrence grade) 1,029 Korean ancestry cases, 395 Korean ancestry controls NA Affymetrix [352228] 0 lumbar disc degeneration http://www.ebi.ac.uk/efo/EFO_0004994 GCST005277 Genome-wide genotyping array 1424 2018-03-29 29378355 Stanne TM 2018-02-01 Thromb Haemost www.ncbi.nlm.nih.gov/pubmed/29378355 A Genome-wide Study of Common and Rare Genetic Variants Associated with Circulating Thrombin Activatable Fibrinolysis Inhibitor. Thrombin-activatable fibrinolysis inhibitor levels 3,116 European ancestry individuals NA Illumina [10000000] (imputed) 7 carboxypeptidase B2 measurement http://www.ebi.ac.uk/efo/EFO_0008069 GCST005412 Genome-wide genotyping array 3116 2018-03-29 29378355 Stanne TM 2018-02-01 Thromb Haemost www.ncbi.nlm.nih.gov/pubmed/29378355 A Genome-wide Study of Common and Rare Genetic Variants Associated with Circulating Thrombin Activatable Fibrinolysis Inhibitor. Thrombin-activatable fibrinolysis inhibitor activation peptide 3,124 European ancestry individuals NA Illumina [10000000] (imputed) 11 thrombin activatable fibrinolysis inhibitor activation peptide measurement http://www.ebi.ac.uk/efo/EFO_0008582 GCST005411 Genome-wide genotyping array 3124 2017-08-16 27500523 Zhou K 2016-09-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27500523 Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin. Response to metformin in type 2 diabetes (HbA1c reduction) 1,372 European ancestry individuals 9,184 European ancestry individuals, 1,196 African American ancestry individuals, 627 Asian American individuals, 743 Latino individuals NR [705124] 1 HbA1c measurement, response to metformin http://www.ebi.ac.uk/efo/EFO_0004541, http://purl.obolibrary.org/obo/GO_1901558 GCST004522 Genome-wide genotyping array 1372 2017-07-27 25521368 Tonjes A 2014-12-18 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/25521368 Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin. Circulating chemerin levels 1,967 European ancestry individuals, 824 Sorbian (founder/genetic isolate) individuals 967 individuals Affymetrix [2023499] (imputed) 6 chemerin measurement http://www.ebi.ac.uk/efo/EFO_0004573 GCST004389 Genome-wide genotyping array 2791 2017-09-28 28680059 Song X 2017-07-05 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28680059 GWAS follow-up study of esophageal squamous cell carcinoma identifies potential genetic loci associated with family history of upper gastrointestinal cancer. Family history of upper gastrointestinal cancer in esophageal squamous cell carcinoma 1,034 East Asian ancestry cases with family history of upper gastrointestinal cancer, 2,268 East Asian ancestry cases without family history of upper gastrointestinal cancer up to 2,801 East Asian ancestry cases with family history of upper gastrointestinal cancer, 3,136 East Asian ancestry cases without family history of upper gastrointestinal cancer NR [NR] (imputed) 0 family history of upper gastrointestinal cancer http://www.ebi.ac.uk/efo/EFO_0008346 GCST004799 Genome-wide genotyping array 3302 2017-09-11 28641744 Guo W 2017-07-01 Eur Neuropsychopharmacol www.ncbi.nlm.nih.gov/pubmed/28641744 Polygenic risk score and heritability estimates reveals a genetic relationship between ASD and OCD. Obsessive-compulsive disorder or autism spectrum disorder 2,998 European ancestry obsessive-compulsive disorder cases, 6,898 European ancestry autism spectrum disorder cases NA Illumina [6995140] (imputed) 13 obsessive-compulsive disorder, autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0004242, http://www.ebi.ac.uk/efo/EFO_0003756 GCST004703 Genome-wide genotyping array 9896 2017-09-18 25676789 Wen CC 2015-05-01 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/25676789 Genome-wide association study identifies ABCG2 (BCRP) as an allopurinol transporter and a determinant of drug response. Serum uric acid levels in response to allopurinol in gout 1,607 European ancestry individuals, 238 East Asian individuals, 84 African American individuals, 85 Hispanic individuals, 13 individuals NA Affymetrix [NR] (imputed) 26 response to allopurinol, uric acid measurement http://www.ebi.ac.uk/efo/EFO_0006337, http://www.ebi.ac.uk/efo/EFO_0004761 GCST004751 Genome-wide genotyping array 2027 2017-10-13 28870582 Wang XF 2017-08-01 J Neurol Sci www.ncbi.nlm.nih.gov/pubmed/28870582 Linking Alzheimer's disease and type 2 diabetes: Novel shared susceptibility genes detected by cFDR approach. Alzheimer's disease or type 2 diabetes (pleiotropy) 17,008 European ancestry Alzheimer's disease cases, 12,171 European ancestry type II diabetes cases, 94,016 European ancestry controls NA NR [262661] (imputed) 0 Alzheimer's disease, type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0001360 GCST004880 Genome-wide genotyping array 123195 2018-01-26 29212897 Salminen A 2017-12-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/29212897 Genetic Variants Contributing to Circulating Matrix Metalloproteinase 8 Levels and Their Association With Cardiovascular Diseases: A Genome-Wide Analysis. Matrix metalloproteinase-8 levels 6,049 Finnish ancestry individuals NA Illumina [at least 2300000] (imputed) 2 matrix metalloproteinase 8 measurement http://www.ebi.ac.uk/efo/EFO_0008466 GCST005187 Genome-wide genotyping array 6049 2018-01-04 29209388 Cho CH 2017-11-07 Psychiatry Investig www.ncbi.nlm.nih.gov/pubmed/29209388 A Genome-Wide Association Study Identifies UTRN Gene Polymorphism for Restless Legs Syndrome in a Korean Population. Restless legs syndrome 325 Korean ancestry cases, 2,603 Korean ancestry controls 227 Korean ancestry cases, 229 Korean ancestry controls Affymetrix [1031877] (imputed) 0 restless legs syndrome http://www.ebi.ac.uk/efo/EFO_0004270 GCST005107 Genome-wide genotyping array 2928 2017-03-30 27611488 Almoguera B 2016-09-09 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/27611488 Identification of Four Novel Loci in Asthma in European American and African American Populations. Adult asthma 337 African American allergic asthma cases, 321 African American non-allergic asthma cases, 1,367 African American controls, 466 European American allergic asthma cases, 626 European American non-allergic asthma cases, 7,878 European American controls NA Affymetrix, Illumina [NR] (imputed) 24 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST003833 Genome-wide genotyping array 10995 2017-03-30 27611488 Almoguera B 2016-09-09 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/27611488 Identification of Four Novel Loci in Asthma in European American and African American Populations. Asthma 819 African American non-allergic asthma cases, 2,218 African American allergic asthma cases 4,360 African American controls, 808 European American non-allergic asthma cases, 1,464 European American allergic asthma cases, 11,975 European American controls NA Affymetrix, Illumina [NR] (imputed) 49 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST003831 Genome-wide genotyping array 21644 2017-03-30 27611488 Almoguera B 2016-09-09 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/27611488 Identification of Four Novel Loci in Asthma in European American and African American Populations. Asthma (childhood onset) 1,181 African American allergic asthma child cases, 498 African American non-allergic asthma child cases, 2,993 African American child controls, 998 European American allergic asthma child cases, 182 European American non-allergic asthma child cases, 4,097 European American child controls. NA Affymetrix, Illumina [NR] (imputed) 27 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST003832 Genome-wide genotyping array 9949 2017-10-20 28869590 Zhao W 2017-09-04 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28869590 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. Type 2 diabetes 6,353 South Asian ancestry cases, 7,179 South Asian ancestry controls, 3,871 European ancestry cases, 16,427 European ancestry controls, 34,840 cases, 114,981 controls 7,888 South Asian ancestry cases, 20,679 South Asian ancestry controls, 387 European ancestry cases, 2,092 European ancestry controls, 19,998 East Asian ancestry cases, 30,983 East Asian ancestry controls Affymetrix, Illumina [NR] (imputed) 157 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST004894 Genome-wide genotyping array 183651 2018-01-18 29213071 Mendez-Giraldez R 2017-12-06 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29213071 GWAS of the electrocardiographic QT interval in Hispanics/Latinos generalizes previously identified loci and identifies population-specific signals. QT interval 15,997 Hispanic/Latino individuals NA Affymetrix, Illumina [up to 17586686] (imputed) 62 QT interval http://www.ebi.ac.uk/efo/EFO_0004682 GCST005171 Genome-wide genotyping array 15997 2017-01-12 27445529 Berube JC 2016-05-04 Can Respir J www.ncbi.nlm.nih.gov/pubmed/27445529 Identification of Susceptibility Genes of Adult Asthma in French Canadian Women. Asthma 240 French Canadian ancestry cases, 120 French Canadian ancestry controls 342 French Canadian ancestry cases, 213 European ancestry cases, 261 French Canadian ancestry controls, 142 European ancestry controls Illumina [730525] 0 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST003521 Genome-wide genotyping array 360 2016-12-16 26989097 Coleman JR 2016-03-17 Br J Psychiatry www.ncbi.nlm.nih.gov/pubmed/26989097 Genome-wide association study of response to cognitive-behavioural therapy in children with anxiety disorders. Response to cognitive-behavioural therapy in anxiety disorder Up to 902 European ancestry cases, up to 78 cases NA Illumina [3017604] (imputed) 12 cognitive behavioural therapy http://www.ebi.ac.uk/efo/EFO_0007820 GCST003469 Genome-wide genotyping array 980 2019-08-12 27903959 Lv H 2017-01-31 Oncotarget www.ncbi.nlm.nih.gov/pubmed/27903959 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. Core binding factor acute myeloid leukemia 175 European ancestry cases, 218 European ancestry controls NA Affymetrix [734624] 1744 acute myeloid leukemia http://www.ebi.ac.uk/efo/EFO_0000222 GCST008413 Genome-wide genotyping array 393 2017-03-24 27723758 Bronson PG 2016-10-10 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27723758 Common variants at PVT1, ATG13-AMBRA1, AHI1 and CLEC16A are associated with selective IgA deficiency. Selective IgA deficiency 1,635 European ancestry cases, 4,852 European ancestry controls NA Illumina [up to 9464381] (imputed) 33 selective IgA deficiency disease http://www.ebi.ac.uk/efo/EFO_1001929 GCST003814 Genome-wide genotyping array 6487 2016-12-06 27064253 Zhou W 2016-04-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27064253 Mosaic loss of chromosome Y is associated with common variation near TCL1A. Mosaic loss of chromosome Y 895 cases, 11,474 controls NA Illumina [2595310] 1 mosaic loss of chromosome Y measurement http://www.ebi.ac.uk/efo/EFO_0007783 GCST003421 Genome-wide genotyping array 12369 2018-09-07 27618448 Liu C 2016-10-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27618448 Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci. Systolic blood pressure 120,473 European ancestry individuals, 21,503 African American individuals, 4,586 Hispanic individuals 154,543 European ancestry individuals, 26,183 South Asian ancestry individuals Illumina [247039] 17 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST006228 Exome genotyping array [Exome array] 146562 2018-09-07 27618448 Liu C 2016-10-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27618448 Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci. Mean arterial pressure 120,473 European ancestry individuals, 21,503 African American individuals, 4,586 Hispanic individuals NA Illumina [247039] 66 mean arterial pressure http://www.ebi.ac.uk/efo/EFO_0006340 GCST006231 Exome genotyping array [Exome array] 146562 2018-09-07 27618448 Liu C 2016-10-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27618448 Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci. Diastolic blood pressure 120,473 European ancestry individuals, 21,503 African American individuals, 4,586 Hispanic individuals 154,543 European ancestry individuals, 26,183 South Asian ancestry individuals Illumina [247039] 17 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST006227 Exome genotyping array [Exome array] 146562 2018-09-07 27618448 Liu C 2016-10-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27618448 Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci. Pulse pressure 120,473 European ancestry individuals, 21,503 African American individuals, 4,586 Hispanic individuals 154,543 European ancestry individuals, 26,183 South Asian ancestry individuals Illumina [247039] 11 pulse pressure measurement http://www.ebi.ac.uk/efo/EFO_0005763 GCST006230 Exome genotyping array [Exome array] 146562 2018-09-07 27618448 Liu C 2016-10-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27618448 Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci. Hypertension 120,473 European ancestry individuals, 21,503 African American individuals, 4,586 Hispanic individuals 154,543 European ancestry individuals, 26,183 South Asian ancestry individuals Illumina [247039] 5 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST006229 Exome genotyping array [Exome array] 146562 2018-02-06 26284813 Hayes MG 2015-08-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26284813 Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations. Luteinizing hormone levels in polycystic ovary syndrome 645 European ancestry cases 607 European ancestry cases Illumina [at least 624044] (imputed) 3 luteinizing hormone measurement http://www.ebi.ac.uk/efo/EFO_0007002 GCST005269 Genome-wide genotyping array 645 2018-02-06 26284813 Hayes MG 2015-08-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26284813 Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations. Follicle stimulating hormone levels in polycystic ovary syndrome 647 European ancestry cases 606 European ancestry cases Illumina [at least 624044] (imputed) 4 follicle stimulating hormone measurement http://www.ebi.ac.uk/efo/EFO_0004768 GCST005270 Genome-wide genotyping array 647 2018-02-06 26284813 Hayes MG 2015-08-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26284813 Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations. Sex hormone-binding globulin levels in polycystic ovary syndrome 903 European ancestry cases 1,156 European ancestry cases Illumina [at least 624044] (imputed) 1 sex hormone-binding globulin measurement http://www.ebi.ac.uk/efo/EFO_0004696 GCST005271 Genome-wide genotyping array 903 2018-02-06 26284813 Hayes MG 2015-08-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26284813 Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations. Testosterone levels in polycystic ovary syndrome 957 European ancestry cases 1,516 European ancestry cases Illumina [at least 624044] (imputed) 4 testosterone measurement http://www.ebi.ac.uk/efo/EFO_0004908 GCST005272 Genome-wide genotyping array 957 2018-02-06 26284813 Hayes MG 2015-08-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26284813 Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations. Polycystic ovary syndrome 984 European ancestry cases, 2,964 European ancestry controls 2,021 European ancestry cases, 2,566 European ancestry controls Illumina [at least 624044] (imputed) 7 polycystic ovary syndrome http://www.ebi.ac.uk/efo/EFO_0000660 GCST005273 Genome-wide genotyping array 3948 2018-02-06 26284813 Hayes MG 2015-08-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26284813 Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations. DHEAS levels in polycystic ovary syndrome up to 984 European ancestry cases up to 2,021 European ancestry cases Illumina [at least 624044] (imputed) 0 dehydroepiandrosterone sulphate measurement http://www.ebi.ac.uk/efo/EFO_0007001 GCST005274 Genome-wide genotyping array 984 2018-02-23 29348612 Wiemels JL 2018-01-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29348612 GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21. Acute lymphoblastic leukemia (childhood) 1,949 Latino cases, 8,584 Latino controls, 1,184 European ancestry cases, 3551 European ancestry controls, 130 African American cases, 3,842 African American controls 959 European ancestry cases, 2,624 European ancestry controls, 530 Latino cases, 511 Latino controls Affymetrix [757935] 9 acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000220 GCST005315 Genome-wide genotyping array 19240 2018-07-04 29278617 Sucheston-Campbell LE 2018-02-01 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/29278617 Genome-wide meta-analyses identifies novel taxane-induced peripheral neuropathy-associated loci. Taxane-induced peripheral neuropathy in breast cancer 204 European ancestry cases with ≥ grade 3 neuropathy, 1,919 European ancestry cases with < grade 3 neuropathy, 31 African American cases with ≥ grade 3 neuropathy, 108 African American cases with 8000000] (imputed) 4 bipolar disorder, response to lithium ion http://www.ebi.ac.uk/efo/EFO_0000289, http://purl.obolibrary.org/obo/GO_0010226 GCST003158 Genome-wide genotyping array 10538 2016-09-27 26503763 Song J 2015-10-27 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/26503763 Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder. Subjective response to lithium treatment in bipolar disorder 1,639 European ancestry responder cases, 1,059 European ancestry non-responder cases NA NR [> 8000000] (imputed) 4 response to lithium ion http://purl.obolibrary.org/obo/GO_0010226 GCST003160 Genome-wide genotyping array 2698 2016-09-27 26503763 Song J 2015-10-27 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/26503763 Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder. Objective response to lithium treatment 323 European ancestry bipolar disorder responder cases, 6,684 European ancestry controls NA Affymetrix, Illumina [> 8000000] (imputed) 4 bipolar disorder, response to lithium ion http://www.ebi.ac.uk/efo/EFO_0000289, http://purl.obolibrary.org/obo/GO_0010226 GCST003159 Genome-wide genotyping array 7007 2016-09-27 26503763 Song J 2015-10-27 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/26503763 Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder. Objective response to lithium treatment in bipolar disorder 323 European ancestry responder cases, 853 European ancestry non-responder cases NA Affymetrix, Illumina [> 8000000] (imputed) 4 response to lithium ion http://purl.obolibrary.org/obo/GO_0010226 GCST003161 Genome-wide genotyping array 1176 2016-10-06 26486471 van Loon J 2015-10-21 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/26486471 Genome-wide association studies identify genetic loci for low von Willebrand factor levels. Low vWF levels up to 1,635 European ancestry individuals with low vWF levels, up to 33,286 European ancestry individuals with normal vWF levels NA Affymetrix, Illumina [~ 2600000] (imputed) 10 von Willebrand factor measurement http://www.ebi.ac.uk/efo/EFO_0004629 GCST003210 Genome-wide genotyping array 34921 2016-10-06 26491034 Sarzynski MA 2015-10-21 Br J Sports Med www.ncbi.nlm.nih.gov/pubmed/26491034 Genomic and transcriptomic predictors of triglyceride response to regular exercise. Response to exercise (triglyceride level interaction) 478 European ancestry individuals from 99 families NA Illumina [2396589] (imputed) 5 triglyceride change measurement, response to exercise http://www.ebi.ac.uk/efo/EFO_0007681, http://www.ebi.ac.uk/efo/EFO_0007768 GCST003207 Genome-wide genotyping array 577 2020-12-01 27432226 Kar SP 2016-07-17 Cancer Discov www.ncbi.nlm.nih.gov/pubmed/27432226 Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types. Breast cancer, ovarian cancer or prostate cancer (pleiotropy) 62,533 European ancestry breast cancer female cases, 60,976 European ancestry controls, 15,437 European ancestry invasive epithelial ovarian cancer female cases, 30,845 European ancestry controls, 34,379 European ancestry prostate cancer male cases, 33,164 European ancestry controls NA Illumina [NR] 18 prostate carcinoma, breast carcinoma, ovarian carcinoma http://www.ebi.ac.uk/efo/EFO_0001663, http://www.ebi.ac.uk/efo/EFO_0000305, http://www.ebi.ac.uk/efo/EFO_0001075 GCST010797 Targeted genotyping array 237334 2017-02-24 27416945 Walford GA 2016-07-14 Diabetes www.ncbi.nlm.nih.gov/pubmed/27416945 Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci. Modified Stumvoll Insulin Sensitivity Index (BMI interaction) 16,753 European ancestry individuals 13,354 European ancestry individuals Affymetrix, Illumina [up to 2400000] (imputed) 12 insulin sensitivity measurement, body mass index http://www.ebi.ac.uk/efo/EFO_0004471, http://www.ebi.ac.uk/efo/EFO_0004340 GCST003659 Genome-wide genotyping array 16753 2018-01-22 27416945 Walford GA 2016-07-14 Diabetes www.ncbi.nlm.nih.gov/pubmed/27416945 Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci. Modified Stumvoll Insulin Sensitivity Index 16,753 European ancestry individuals 13,354 European ancestry individuals Affymetrix, Illumina [up to 2400000] (imputed) 1 insulin sensitivity measurement http://www.ebi.ac.uk/efo/EFO_0004471 GCST005178 Genome-wide genotyping array 16753 2017-02-24 27416945 Walford GA 2016-07-14 Diabetes www.ncbi.nlm.nih.gov/pubmed/27416945 Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci. Modified Stumvoll Insulin Sensitivity Index (model adjusted for BMI) 16,753 European ancestry individuals 13,354 European ancestry individuals Affymetrix, Illumina [up to 2400000] (imputed) 4 insulin sensitivity measurement, body mass index http://www.ebi.ac.uk/efo/EFO_0004471, http://www.ebi.ac.uk/efo/EFO_0004340 GCST003658 Genome-wide genotyping array 16753 2018-04-26 25337690 Redler S 2015-03-01 J Invest Dermatol www.ncbi.nlm.nih.gov/pubmed/25337690 Immunochip-based analysis: high-density genotyping of immune-related loci sheds further light on the autoimmune genetic architecture of alopecia areata. Alopecia areata 767 European ancestry cases, 1,475 European ancestry controls 1,016 European ancestry cases, 1,060 European ancestry controls Illumina [146703] 2 alopecia areata http://www.ebi.ac.uk/efo/EFO_0004192 GCST005539 Targeted genotyping array [ImmunoChip] 2242 2017-09-15 28662289 Lin YY 2017-06-29 Cancer www.ncbi.nlm.nih.gov/pubmed/28662289 Genome-wide association analysis identifies a GLUL haplotype for familial hepatitis B virus-related hepatocellular carcinoma. Familial hepatitis B virus-related hepatocellular carcinoma 139 East Asian ancestry cases, 139 East Asian ancestry controls NA Affymetrix [641398] 4 hepatocellular carcinoma http://www.ebi.ac.uk/efo/EFO_0000182 GCST004736 Genome-wide genotyping array 278 2018-01-08 29186428 Tonjes A 2017-11-27 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/29186428 Genome-wide meta-analysis identifies novel determinants of circulating serum progranulin. Progranulin levels 1,963 European ancestry individuals, 848 Sorbian (founder/genetic isolate) individuals 1800 European ancestry individuals Affymetrix [2069113] (imputed) 3 progranulin measurement http://www.ebi.ac.uk/efo/EFO_0004625 GCST005109 Genome-wide genotyping array 2811 2018-08-10 28373541 Yang J 2017-04-03 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/28373541 Genetic signatures of high-altitude adaptation in Tibetans. High altitude adaptation 3,008 Tibetan (founder/genetic isolate) individuals and 7,287 East Asian individuals NA Illumina [7300000] (imputed) 9 high altitude adaptation http://www.ebi.ac.uk/efo/EFO_0009105 GCST006054 Genome-wide genotyping array 10295 2018-01-26 29195075 Martin AR 2017-11-30 Cell www.ncbi.nlm.nih.gov/pubmed/29195075 An Unexpectedly Complex Architecture for Skin Pigmentation in Africans. Tanning 216 Sub-Saharan African ancestry individuals 240 Sub-Saharan African ancestry individuals Illumina [at least 241929] (imputed) 5 suntan http://www.ebi.ac.uk/efo/EFO_0004279 GCST005189 Genome-wide genotyping array 216 2018-01-26 29195075 Martin AR 2017-11-30 Cell www.ncbi.nlm.nih.gov/pubmed/29195075 An Unexpectedly Complex Architecture for Skin Pigmentation in Africans. Skin pigmentation 216 Sub-Saharan African ancestry individuals 240 Sub-Saharan African ancestry individuals Illumina [at least 241929] (imputed) 3 skin pigmentation measurement http://www.ebi.ac.uk/efo/EFO_0007009 GCST005188 Genome-wide genotyping array 216 2016-10-04 26482879 Paternoster L 2015-10-19 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26482879 Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. Atopic dermatitis 18,900 European ancestry cases, 1,472 Japanese ancestry cases, 422 African American cases, 300 Latino cases, 305 cases, 84,166 European ancestry controls, 7,966 Japanese ancestry controls, 844 African American controls, 1,592 Latino controls, 896 controls 30,588 European ancestry cases, 459 African American cases, 1,012 Chinese ancestry cases, 226,537 European ancestry controls, 729 African American controls, 1,362 Chinese ancestry controls Illumina [15539996] (imputed) 40 atopic eczema http://www.ebi.ac.uk/efo/EFO_0000274 GCST003184 Genome-wide genotyping array 116863 2017-03-29 26503814 Hardin M 2016-10-27 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/26503814 A genome-wide analysis of the response to inhaled β2-agonists in chronic obstructive pulmonary disease. Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) 5,766 European ancestry cases, 811 African American cases NA Illumina [NR] (imputed) 57 FEV change measurement, response to bronchodilator http://www.ebi.ac.uk/efo/EFO_0005921, http://purl.obolibrary.org/obo/GO_0097366 GCST003830 Genome-wide genotyping array 6577 2016-10-13 26503584 Litchfield K 2015-10-27 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26503584 Identification of four new susceptibility loci for testicular germ cell tumour. Testicular germ cell tumor 986 European ancestry cases, 4,946 European ancestry controls 4,009 cases, 4,066 controls Illumina [~ 8900000] (imputed) 3 Testicular Germ Cell Tumor http://www.ebi.ac.uk/efo/EFO_1000566 GCST003247 Genome-wide genotyping array 5932 2016-10-13 26503584 Litchfield K 2015-10-27 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26503584 Identification of four new susceptibility loci for testicular germ cell tumour. Testicular germ cell tumor 986 European ancestry cases, 4,946 European ancestry controls 1,064 European ancestry cases, 4,009 cases, 10,082 European ancestry controls, 4,066 controls Illumina [307291] 3 Testicular Germ Cell Tumor http://www.ebi.ac.uk/efo/EFO_1000566 GCST003246 Genome-wide genotyping array 5932 2016-09-23 26488411 Matsukura M 2015-10-21 PLoS One www.ncbi.nlm.nih.gov/pubmed/26488411 Genome-Wide Association Study of Peripheral Arterial Disease in a Japanese Population. Peripheral artery disease 785 Japanese ancestry cases, 3,383 Japanese ancestry controls 2,379 Japanese ancestry cases, 16,752 Japanese ancestry controls Illumina [431666] 4 peripheral arterial disease http://www.ebi.ac.uk/efo/EFO_0004265 GCST003154 Genome-wide genotyping array 4168 2017-10-24 28898252 Wheeler E 2017-09-12 PLoS Med www.ncbi.nlm.nih.gov/pubmed/28898252 Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. Glycated hemoglobin levels 88,355 European ancestry individuals,18,472 East Asian ancestry individuals, 7,572 South Asian ancestry individuals, 7,564 African American individuals 33,238 European ancestry individuals, 2,366 East Asian ancestry individuals, 1,302 South Asian ancestry individuals Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 0 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST004903 Genome-wide genotyping array 121963 2019-06-21 28898252 Wheeler E 2017-09-12 PLoS Med www.ncbi.nlm.nih.gov/pubmed/28898252 Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. Glycated hemoglobin levels 7,572 South Asian ancestry individuals NA Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 1 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST007951 Genome-wide genotyping array 7572 2019-06-21 28898252 Wheeler E 2017-09-12 PLoS Med www.ncbi.nlm.nih.gov/pubmed/28898252 Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. Glycated hemoglobin levels 88,355 European ancestry individuals NA Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 52 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST007954 Genome-wide genotyping array 88355 2019-06-21 28898252 Wheeler E 2017-09-12 PLoS Med www.ncbi.nlm.nih.gov/pubmed/28898252 Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. Glycated hemoglobin levels 7,564 African American individuals NA Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 2 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST007952 Genome-wide genotyping array 7564 2019-06-21 28898252 Wheeler E 2017-09-12 PLoS Med www.ncbi.nlm.nih.gov/pubmed/28898252 Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. Glycated hemoglobin levels 18,472 East Asian ancestry individuals NA Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 14 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST007953 Genome-wide genotyping array 18472 2017-11-20 28746715 Smeland OB 2017-07-26 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/28746715 Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function. Schizophrenia or general cognitive function (pleiotropy) 34,486 schizophrenia cases, 45,271 controls, 81,837 individuals with cognitive function data NA Affymetrix [NR] 0 schizophrenia, cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0008354 GCST004975 Genome-wide genotyping array 161594 2017-11-20 28746715 Smeland OB 2017-07-26 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/28746715 Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function. Schizophrenia or reaction time (pleiotropy) 34,486 schizophrenia cases, 45,271 controls, 111,483 individuals with reaction time data NA Affymetrix [NR] 0 schizophrenia, reaction time measurement http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0008393 GCST004974 Genome-wide genotyping array 191240 2017-11-20 28746715 Smeland OB 2017-07-26 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/28746715 Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function. Schizophrenia or verbal-numerical reasoning (pleiotropy) 34,486 schizophrenia cases, 45,271 controls, 36,035 individuals with verbal-numerical reasoning data NA Affymetrix [NR] 0 schizophrenia, verbal-numerical reasoning measurement http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0008394 GCST004973 Genome-wide genotyping array 115792 2018-07-02 29325163 Hong J 2018-01-09 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/29325163 Trans-ethnic Evaluation Identifies Novel Low Frequency Loci Associated with 25-Hydroxyvitamin D Concentrations. Serum 25-Hydroxyvitamin D levels 8,541 African American individuals, 3,485 Hispanic American individuals, 16,124 European ancestry individuals NA Affymetrix, Illumina [at least 398246] (imputed) 15 vitamin D measurement http://www.ebi.ac.uk/efo/EFO_0004631 GCST005782 Genome-wide genotyping array 28150 2017-09-22 28739976 Wain LV 2017-07-24 Hypertension www.ncbi.nlm.nih.gov/pubmed/28739976 Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney. Diastolic blood pressure 150,134 European ancestry individuals 87,359 European ancestry individuals, 140,886 European and unknown ancestry individuals Affymetrix, Illumina, Perlegen [7994604] (imputed) 71 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST004777 Genome-wide genotyping array 150134 2017-09-22 28739976 Wain LV 2017-07-24 Hypertension www.ncbi.nlm.nih.gov/pubmed/28739976 Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney. Systolic blood pressure 150,134 European ancestry individuals 87,359 European ancestry individuals, 140,886 European and unknown ancestry individuals Affymetrix, Illumina, Perlegen [7994604] (imputed) 96 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST004776 Genome-wide genotyping array 150134 2017-09-22 28739976 Wain LV 2017-07-24 Hypertension www.ncbi.nlm.nih.gov/pubmed/28739976 Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney. Pulse pressure 150,134 European ancestry individuals 87,359 European ancestry individuals, 140,886 European and unknown ancestry individuals Affymetrix, Illumina, Perlegen [7994604] (imputed) 46 pulse pressure measurement http://www.ebi.ac.uk/efo/EFO_0005763 GCST004775 Genome-wide genotyping array 150134 2017-10-09 28754779 Rosendahl J 2017-07-28 Gut www.ncbi.nlm.nih.gov/pubmed/28754779 Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis. Alcoholic chronic pancreatitis 1,959 European ancestry cases, 1,488 European ancestry alcohol abuse controls, 4,552 European ancestry controls NA Illumina [9389922] (imputed) 156 alcoholic pancreatitis http://www.ebi.ac.uk/efo/EFO_1002013 GCST004860 Genome-wide genotyping array 7999 2017-02-03 27439200 Nieuwenhuis MA 2016-07-20 Allergy www.ncbi.nlm.nih.gov/pubmed/27439200 Combining genomewide association study and lung eQTL analysis provides evidence for novel genes associated with asthma. Bronchial hyperresponsiveness in asthma 920 Dutch ancestry cases, 980 Dutch ancestry controls 2,589 European ancestry cases, 473 cases, 6,702 European ancestry controls, 1,892 controls Illumina [294932] 1 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST003589 Genome-wide genotyping array 1900 2018-01-29 29198719 Shaffer JR 2017-11-30 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29198719 Multiethnic GWAS Reveals Polygenic Architecture of Earlobe Attachment. Lobe attachment (rater-scored or self-reported) 66,741 European ancestry individuals, 5,062 Hispanic individuals, 2,857 Han Chinese ancestry individuals NA Illumina [at least 7383741] (imputed) 178 lobe attachment http://www.ebi.ac.uk/efo/EFO_0007667 GCST005192 Genome-wide genotyping array 74660 2018-01-29 29198719 Shaffer JR 2017-11-30 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29198719 Multiethnic GWAS Reveals Polygenic Architecture of Earlobe Attachment. Lobe attachment (rater scored) 1791 European ancestry individuals, 5,062 Hispanic individuals, 2,857 Han Chinese ancestry individuals NA Illumina [at least 7383741] (imputed) 19 lobe attachment http://www.ebi.ac.uk/efo/EFO_0007667 GCST005193 Genome-wide genotyping array 9710 2018-01-12 29186694 Lam M 2017-11-28 Cell Rep www.ncbi.nlm.nih.gov/pubmed/29186694 Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets. Cognitive ability 107,207 European ancestry individuals NA Affymetrix, Illumina [7357080] (imputed) 69 intelligence http://www.ebi.ac.uk/efo/EFO_0004337 GCST005142 Genome-wide genotyping array 107207 2018-01-12 29186694 Lam M 2017-11-28 Cell Rep www.ncbi.nlm.nih.gov/pubmed/29186694 Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets. Cognitive ability (MTAG) 436,124 European ancestry individuals NA Affymetrix, Illumina, Perlegen [7333576] (imputed) 82 intelligence, self reported educational attainment http://www.ebi.ac.uk/efo/EFO_0004337, http://www.ebi.ac.uk/efo/EFO_0004784 GCST005141 Genome-wide genotyping array 436124 2018-02-02 29187748 Morey RA 2017-11-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29187748 Genome-wide association study of subcortical brain volume in PTSD cases and trauma-exposed controls. Caudate volume in trauma-exposed individuals 36 African American post-traumatic stress disorder cases, 38 African American trauma-exposed controls, 30 European ancestry post-traumatic stress disorder cases, 53 European ancestry trauma-exposed controls NA Illumina [2711511] (imputed) 2 response to trauma exposure, caudate nucleus volume http://www.ebi.ac.uk/efo/EFO_0008483, http://www.ebi.ac.uk/efo/EFO_0004830 GCST005240 Genome-wide genotyping array 157 2018-02-02 29187748 Morey RA 2017-11-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29187748 Genome-wide association study of subcortical brain volume in PTSD cases and trauma-exposed controls. Nucleus accumbens volume in trauma-exposed individuals 36 African American post-traumatic stress disorder cases, 38 African American trauma-exposed controls, 30 European ancestry post-traumatic stress disorder cases, 53 European ancestry trauma-exposed controls NA Illumina [2711511] (imputed) 4 response to trauma exposure, nucleus accumbens volume http://www.ebi.ac.uk/efo/EFO_0008483, http://www.ebi.ac.uk/efo/EFO_0006931 GCST005241 Genome-wide genotyping array 157 2018-02-02 29187748 Morey RA 2017-11-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29187748 Genome-wide association study of subcortical brain volume in PTSD cases and trauma-exposed controls. Pallidum volume in trauma-exposed individuals 36 African American post-traumatic stress disorder cases, 38 African American trauma-exposed controls, 30 European ancestry post-traumatic stress disorder cases, 53 European ancestry trauma-exposed controls NA Illumina [2711511] (imputed) 1 pallidum volume, response to trauma exposure http://www.ebi.ac.uk/efo/EFO_0006933, http://www.ebi.ac.uk/efo/EFO_0008483 GCST005242 Genome-wide genotyping array 157 2018-02-02 29187748 Morey RA 2017-11-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29187748 Genome-wide association study of subcortical brain volume in PTSD cases and trauma-exposed controls. Amygdala volume in trauma-exposed individuals 36 African American post-traumatic stress disorder cases, 38 African American trauma-exposed controls, 30 European ancestry post-traumatic stress disorder cases, 53 European ancestry trauma-exposed controls NA Illumina [2711511] (imputed) 0 response to trauma exposure, amygdala volume http://www.ebi.ac.uk/efo/EFO_0008483, http://www.ebi.ac.uk/efo/EFO_0006934 GCST005239 Genome-wide genotyping array 157 2018-02-02 29187748 Morey RA 2017-11-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29187748 Genome-wide association study of subcortical brain volume in PTSD cases and trauma-exposed controls. Hippocampal volume in trauma-exposed individuals 36 African American post-traumatic stress disorder cases, 38 African American trauma-exposed controls, 30 European ancestry post-traumatic stress disorder cases, 53 European ancestry trauma-exposed controls NA Illumina [2711511] (imputed) 0 response to trauma exposure, hippocampal volume http://www.ebi.ac.uk/efo/EFO_0008483, http://www.ebi.ac.uk/efo/EFO_0005035 GCST005243 Genome-wide genotyping array 157 2018-02-02 29187748 Morey RA 2017-11-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29187748 Genome-wide association study of subcortical brain volume in PTSD cases and trauma-exposed controls. Putamen volume in trauma-exposed individuals 36 African American post-traumatic stress disorder cases, 38 African American trauma-exposed controls, 30 European ancestry post-traumatic stress disorder cases, 53 European ancestry trauma-exposed controls NA Illumina [2711511] (imputed) 0 response to trauma exposure, putamen volume http://www.ebi.ac.uk/efo/EFO_0008483, http://www.ebi.ac.uk/efo/EFO_0006932 GCST005244 Genome-wide genotyping array 157 2018-02-12 29187748 Morey RA 2017-11-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29187748 Genome-wide association study of subcortical brain volume in PTSD cases and trauma-exposed controls. Lateral ventricle volume in trauma-exposed individuals 36 African American post-traumatic stress disorder cases, 38 African American trauma-exposed controls, 30 European ancestry post-traumatic stress disorder cases, 53 European ancestry trauma-exposed controls NA Illumina [2711511] (imputed) 1 lateral ventricle volume measurement, response to trauma exposure http://www.ebi.ac.uk/efo/EFO_0008487, http://www.ebi.ac.uk/efo/EFO_0008483 GCST005286 Genome-wide genotyping array 157 2018-02-02 29187748 Morey RA 2017-11-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29187748 Genome-wide association study of subcortical brain volume in PTSD cases and trauma-exposed controls. Thalamus volume in trauma-exposed individuals 36 African American post-traumatic stress disorder cases, 38 African American trauma-exposed controls, 30 European ancestry post-traumatic stress disorder cases, 53 European ancestry trauma-exposed controls NA Illumina [2711511] (imputed) 0 response to trauma exposure, thalamus volume http://www.ebi.ac.uk/efo/EFO_0008483, http://www.ebi.ac.uk/efo/EFO_0006935 GCST005245 Genome-wide genotyping array 157 2017-09-29 28794112 Christophersen IE 2017-08-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/28794112 Fifteen Genetic Loci Associated With the Electrocardiographic P Wave. P wave terminal force 33,955 European ancestry individuals, 6,778 African individuals NA Affymetrix, Illumina [at least 2402234] (imputed) 12 P wave terminal force measurement http://www.ebi.ac.uk/efo/EFO_0008379 GCST004824 Genome-wide genotyping array 40733 2017-09-29 28794112 Christophersen IE 2017-08-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/28794112 Fifteen Genetic Loci Associated With the Electrocardiographic P Wave. P wave duration 37,678 European ancestry individuals, 6,778 African ancestry individuals NA Affymetrix, Illumina [at least 2402234] (imputed) 20 P wave duration http://www.ebi.ac.uk/efo/EFO_0005094 GCST004826 Genome-wide genotyping array 44456 2018-02-27 29315334 Broce I 2018-01-09 PLoS Med www.ncbi.nlm.nih.gov/pubmed/29315334 Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies. Frontotemporal dementia and immune-mediated diseases (pleiotropy) 2,154 frontotemporal dementia cases, 4,308 controls, 51,109 Crohn's disease cases and controls, 26,405 ulcerative colitis cases and controls, 25,708 rheumatoid arthritis cases and controls, 16,559 type 1 diabetes cases and controls,15,283 celiac disease cases and controls, 7,484 psoriasis cases and controls NA NR [at least 528969] 0 rheumatoid arthritis, psoriasis, celiac disease, Frontotemporal dementia, ulcerative colitis, Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0000676, http://www.ebi.ac.uk/efo/EFO_0001060, http://www.orpha.net/ORDO/Orphanet_282, http://www.ebi.ac.uk/efo/EFO_0000729, http://www.ebi.ac.uk/efo/EFO_0000384 GCST005319 Genome-wide genotyping array 149011 2018-02-27 29315334 Broce I 2018-01-09 PLoS Med www.ncbi.nlm.nih.gov/pubmed/29315334 Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies. Progressive supranuclear palsy and immune-mediated diseases (pleiotropy) 1,114 progressive supranuclear palsy cases, 3,247 controls, 51,109 Crohn's disease cases and controls, 26,405 ulcerative colitis cases and controls, 25,708 rheumatoid arthritis cases and controls, 16,559 type 1 diabetes cases and controls,15,283 celiac disease cases and controls, 7,484 psoriasis cases and controls NA NR [at least 528969] 0 rheumatoid arthritis, type I diabetes mellitus, psoriasis, celiac disease, ulcerative colitis, Crohn's disease, Progressive supranuclear palsy http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0001359, http://www.ebi.ac.uk/efo/EFO_0000676, http://www.ebi.ac.uk/efo/EFO_0001060, http://www.ebi.ac.uk/efo/EFO_0000729, http://www.ebi.ac.uk/efo/EFO_0000384, http://www.orpha.net/ORDO/Orphanet_683 GCST005320 Genome-wide genotyping array 146910 2018-02-27 29315334 Broce I 2018-01-09 PLoS Med www.ncbi.nlm.nih.gov/pubmed/29315334 Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies. Amyotrophic lateral sclerosis and immune-mediated diseases (pleiotropy) 12,577 amyotrophic lateral sclerosis cases, 23,475 controls, 51,109 Crohn's disease cases and controls, 26,405 ulcerative colitis cases and controls, 25,708 rheumatoid arthritis cases and controls, 16,559 type 1 diabetes cases and controls,15,283 celiac disease cases and controls, 7,484 psoriasis cases and controls NA NR [at least 528969] 0 rheumatoid arthritis, type I diabetes mellitus, psoriasis, amyotrophic lateral sclerosis, celiac disease, ulcerative colitis, Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0001359, http://www.ebi.ac.uk/efo/EFO_0000676, http://www.ebi.ac.uk/efo/EFO_0000253, http://www.ebi.ac.uk/efo/EFO_0001060, http://www.ebi.ac.uk/efo/EFO_0000729, http://www.ebi.ac.uk/efo/EFO_0000384 GCST005321 Genome-wide genotyping array 178601 2018-02-27 29315334 Broce I 2018-01-09 PLoS Med www.ncbi.nlm.nih.gov/pubmed/29315334 Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies. Corticobasal degeneration and immune-mediated diseases (pleiotropy) 152 corticobasal degeneration cases, 3,311 controls, 51,109 Crohn's disease cases and controls, 26,405 ulcerative colitis cases and controls, 25,708 rheumatoid arthritis cases and controls, 16,559 type 1 diabetes cases and controls,15,283 celiac disease cases and controls, 7,484 psoriasis cases and controls NA NR [at least 528969] 0 Corticobasal degeneration, rheumatoid arthritis, type I diabetes mellitus, psoriasis, celiac disease, ulcerative colitis, Crohn's disease http://www.orpha.net/ORDO/Orphanet_278, http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0001359, http://www.ebi.ac.uk/efo/EFO_0000676, http://www.ebi.ac.uk/efo/EFO_0001060, http://www.ebi.ac.uk/efo/EFO_0000729, http://www.ebi.ac.uk/efo/EFO_0000384 GCST005322 Genome-wide genotyping array 146012 2019-07-17 25743335 Taylor PN 2015-03-06 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25743335 Whole-genome sequence-based analysis of thyroid function. Thyroid stimulating hormone levels 2,287 European ancestry whole-genome sequenced individuals, 14,048 European ancestry individuals NA Illumina [at least 9558836] (imputed) 13 thyroid stimulating hormone measurement http://www.ebi.ac.uk/efo/EFO_0004748 GCST008165 Genome-wide genotyping array, Genome-wide sequencing 16335 2019-07-17 25743335 Taylor PN 2015-03-06 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25743335 Whole-genome sequence-based analysis of thyroid function. Free thyroxine concentration 2,287 European ancestry whole-genome sequenced individuals, 11,364 European ancestry individuals NA Illumina [at least 9558836] (imputed) 4 thyroxine measurement http://www.ebi.ac.uk/efo/EFO_0005130 GCST008164 Genome-wide genotyping array, Genome-wide sequencing 13651 2018-02-21 29317701 Rappoport N 2018-01-09 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29317701 A genome-wide association study identifies only two ancestry specific variants associated with spontaneous preterm birth. Spontaneous preterm birth (preterm birth) 260 European ancestry cases, 190 African-American cases, 745 Hispanic cases, 131 East Asian ancestry cases, 23 South East Asian ancestry cases, 9,630 European ancestry controls, 1,684 African-American controls, 1,102 Hispanic controls, 118 East Asian ancestry controls, 36 South East Asian ancestry controls 145 African American cases, 307 Latino cases, 82 European ancestry cases, 1,274 African American controls, 2,826 Hispanic / Latino controls, 249 European ancestry controls Illumina [2015750] 0 spontaneous preterm birth http://www.ebi.ac.uk/efo/EFO_0006917 GCST005313 Genome-wide genotyping array 13919 2017-09-28 28714975 Nelson CP 2017-07-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28714975 Association analyses based on false discovery rate implicate new loci for coronary artery disease. Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) 18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls 57,347 European and unknown ancestry cases, 219,521 European and unknown ancestry controls Affymetrix [9149595] (imputed) 72 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST004787 Genome-wide genotyping array 63731 2018-07-23 27018472 Leslie EJ 2016-04-07 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27018472 A Genome-wide Association Study of Nonsyndromic Cleft Palate Identifies an Etiologic Missense Variant in GRHL3. Cleft palate 38 European ancestry cases, 835 European ancestry controls, 21 Hispanic cases, 626 Hispanic controls, 2 Asian ancestry cases, 161 Asian ancestry controls, 38 Indian ancestry controls, 15 Sub-Saharan African ancestry cases, 2 African American cases, 68 Sub-Saharan African ancestry controls, 5 African American controls, 1 African control, 4 controls 246 European ancestry cases, 1,685 European ancestry controls Illumina [34985077] (imputed) 22 Cleft palate http://purl.obolibrary.org/obo/HP_0000175 GCST005946 Genome-wide genotyping array 1816 2018-07-23 27018472 Leslie EJ 2016-04-07 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27018472 A Genome-wide Association Study of Nonsyndromic Cleft Palate Identifies an Etiologic Missense Variant in GRHL3. Cleft palate 114 European ancestry case-parent trios, 30 Hispanic case-parent trios, 39 East Asian case-parent trios, 1 South East Asian ancestry case-parent trio, 5 Sub-Saharan African case-parent trios NA Illumina [34985077] (imputed) 4 Cleft palate http://purl.obolibrary.org/obo/HP_0000175 GCST005948 Genome-wide genotyping array 189 2018-07-23 27018472 Leslie EJ 2016-04-07 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27018472 A Genome-wide Association Study of Nonsyndromic Cleft Palate Identifies an Etiologic Missense Variant in GRHL3. Cleft palate 38 European ancestry cases, 835 European ancestry controls, 21 Hispanic cases, 626 Hispanic controls, 2 Asian ancestry cases, 161 Asian ancestry controls, 38 Indian ancestry controls, 15 Sub-Saharan African ancestry cases, 2 African American cases, 68 Sub-Saharan African ancestry controls, 5 African American controls, 1 African control, 4 controls, 114 European ancestry case-parent trios, 30 Hispanic case-parent trios, 39 East Asian case-parent trios, 1 South East Asian ancestry case-parent trio, 5 Sub-Saharan African case-parent trios 246 European ancestry cases, 1,685 European ancestry controls Illumina [34985077] (imputed) 13 Cleft palate http://purl.obolibrary.org/obo/HP_0000175 GCST005947 Genome-wide genotyping array 2005 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Chickenpox 107,769 European ancestry cases, 15,982 European ancestry controls NA Illumina [at least 560000] (imputed) 36 susceptibility to chickenpox measurement http://www.ebi.ac.uk/efo/EFO_0008400 GCST004999 Genome-wide genotyping array 123751 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Shingles 16,711 European ancestry cases, 118,152 European ancestry controls NA Illumina [at least 560000] (imputed) 75 susceptibility to shingles measurement http://www.ebi.ac.uk/efo/EFO_0008401 GCST005001 Genome-wide genotyping array 134863 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Cold sores 25,108 European ancestry cases, 63,332 European ancestry controls NA Illumina [at least 560000] (imputed) 49 susceptibility to cold sores measurement http://www.ebi.ac.uk/efo/EFO_0008402 GCST005000 Genome-wide genotyping array 88440 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Mumps 31,227 European ancestry cases, 54,153 European ancestry controls NA Illumina [at least 560000] (imputed) 55 susceptibility to mumps measurement http://www.ebi.ac.uk/efo/EFO_0008404 GCST005003 Genome-wide genotyping array 85380 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Plantar warts 24,994 European ancestry cases, 37,451 European ancestry controls NA Illumina [at least 560000] (imputed) 81 susceptibility to plantar warts measurement http://www.ebi.ac.uk/efo/EFO_0008406 GCST005005 Genome-wide genotyping array 62445 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Tuberculosis 4,426 European ancestry cases, 84,290 European ancestry controls NA Illumina [at least 560000] (imputed) 67 susceptibility to Mycobacterium tuberculosis infection measurement http://www.ebi.ac.uk/efo/EFO_0008407 GCST005006 Genome-wide genotyping array 88716 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Bacterial meningitis 842 European ancestry cases, 82,778 European ancestry controls NA Illumina [at least 560000] (imputed) 38 susceptibility to bacterial meningitis measurement http://www.ebi.ac.uk/efo/EFO_0008411 GCST005010 Genome-wide genotyping array 83620 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Yeast infection 52,218 European ancestry cases, 10,235 European ancestry controls NA Illumina [at least 560000] (imputed) 51 susceptibility to vaginal yeast infection measurement http://www.ebi.ac.uk/efo/EFO_0008412 GCST005011 Genome-wide genotyping array 62453 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Myringotomy 4,138 European ancestry cases, 85,089 European ancestry controls NA Illumina [at least 560000] (imputed) 34 susceptibility to childhood ear infection measurement http://www.ebi.ac.uk/efo/EFO_0007904 GCST005015 Genome-wide genotyping array 89227 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Measles 38,219 European ancestry cases, 47,279 European ancestry controls NA Illumina [at least 560000] (imputed) 32 susceptibility to measles measurement http://www.ebi.ac.uk/efo/EFO_0008414 GCST005016 Genome-wide genotyping array 85498 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Hepatitis A 2,442 European ancestry cases, 217,137 European ancestry controls NA Illumina [at least 560000] (imputed) 36 susceptibility to hepatitis A infection measurement http://www.ebi.ac.uk/efo/EFO_0008415 GCST005017 Genome-wide genotyping array 219579 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Rheumatic fever 1,115 European ancestry cases, 88,076 European ancestry controls NA Illumina [at least 560000] (imputed) 24 susceptibility to rheumatic fever measurement http://www.ebi.ac.uk/efo/EFO_0008416 GCST005018 Genome-wide genotyping array 89191 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Number of common colds 43,826 European ancestry cases, 15,720 European ancestry controls NA Illumina [at least 560000] (imputed) 34 susceptibility to common cold measurement http://www.ebi.ac.uk/efo/EFO_0008417 GCST005019 Genome-wide genotyping array 59546 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Chronic sinus infection 5,291 European ancestry cases, 79,622 European ancestry controls NA Illumina [at least 560000] (imputed) 45 susceptibility to chronic sinus infection measurement http://www.ebi.ac.uk/efo/EFO_0008419 GCST005021 Genome-wide genotyping array 84913 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Urinary tract infection frequency 35,000 European ancestry cases, 33,478 European ancestry controls NA Illumina [at least 560000] (imputed) 61 susceptibility to urinary tract infection measurement http://www.ebi.ac.uk/efo/EFO_0008413 GCST005012 Genome-wide genotyping array 68478 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Tonsillectomy 60,098 European ancestry cases, 113,323 European ancestry controls NA Illumina [at least 560000] (imputed) 204 tonsillectomy risk measurement http://www.ebi.ac.uk/efo/EFO_0007924 GCST005014 Genome-wide genotyping array 173421 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Childhood ear infection 46,936 European ancestry cases, 74,874 European ancestry controls NA Illumina [at least 560000] (imputed) 102 susceptibility to childhood ear infection measurement http://www.ebi.ac.uk/efo/EFO_0007904 GCST005013 Genome-wide genotyping array 121810 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Rubella 12,000 European ancestry cases, 71,597 European ancestry controls NA Illumina [at least 560000] (imputed) 38 susceptibility to rubella infection measurement http://www.ebi.ac.uk/efo/EFO_0008418 GCST005020 Genome-wide genotyping array 83597 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Mononucleosis 17,457 European ancestry cases, 68,446 European ancestry controls NA Illumina [at least 560000] (imputed) 44 susceptibility to mononucleosis measurement http://www.ebi.ac.uk/efo/EFO_0008403 GCST005002 Genome-wide genotyping array 85903 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Hepatitis B 1,425 European ancestry cases, 218,180 European ancestry controls NA Illumina [at least 560000] (imputed) 39 susceptibility to hepatitis B infection measurement http://www.ebi.ac.uk/efo/EFO_0008405 GCST005004 Genome-wide genotyping array 219605 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Strep throat 52,487 European ancestry cases, 22,017 European ancestry controls NA Illumina [at least 560000] (imputed) 53 susceptibility to strep throat measurement http://www.ebi.ac.uk/efo/EFO_0008408 GCST005007 Genome-wide genotyping array 74504 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Scarlet fever 6,812 European ancestry cases, 113,837 European ancestry controls NA Illumina [at least 560000] (imputed) 59 susceptibility to scarlet fever measurement http://www.ebi.ac.uk/efo/EFO_0008409 GCST005008 Genome-wide genotyping array 120649 2017-12-01 28928442 Tian C 2017-09-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28928442 Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections. Pneumonia 40,600 European ancestry cases, 90,039 European ancestry controls NA Illumina [at least 560000] (imputed) 67 susceptibility to pneumonia measurement http://www.ebi.ac.uk/efo/EFO_0008410 GCST005009 Genome-wide genotyping array 130639 2018-01-19 29221444 Divers J 2017-12-08 BMC Genet www.ncbi.nlm.nih.gov/pubmed/29221444 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes. Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes 345 African American cases, 346 African American controls 137 African American cases, 68 African American controls Illumina [at least 13000000] (imputed) 84 coronary artery calcification http://www.ebi.ac.uk/efo/EFO_0004723 GCST005173 Genome-wide genotyping array 691 2018-01-19 29221444 Divers J 2017-12-08 BMC Genet www.ncbi.nlm.nih.gov/pubmed/29221444 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes. Coronary artery calcified atherosclerotic plaque score in type 2 diabetes 691 African American individuals 205 African American individuals Illumina [at least 13000000] (imputed) 53 coronary artery calcification http://www.ebi.ac.uk/efo/EFO_0004723 GCST005174 Genome-wide genotyping array 691 2018-01-19 29221444 Divers J 2017-12-08 BMC Genet www.ncbi.nlm.nih.gov/pubmed/29221444 Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes. Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes 345 African American cases, 346 African American controls 137 African American cases, 68 African American controls Illumina [at least 13000000] (imputed) 68 coronary artery calcification http://www.ebi.ac.uk/efo/EFO_0004723 GCST005175 Genome-wide genotyping array 691 2018-08-16 22205395 Tekola Ayele F 2011-12-29 Immunogenetics www.ncbi.nlm.nih.gov/pubmed/22205395 Genome-wide associated loci influencing interleukin (IL)-10, IL-1Ra, and IL-6 levels in African Americans. Interleukin-10 levels 704 African American individuals 425 West African individuals Affymetrix [5396780] (imputed) 15 interleukin 10 measurement http://www.ebi.ac.uk/efo/EFO_0004750 GCST006102 Genome-wide genotyping array 704 2018-08-16 22205395 Tekola Ayele F 2011-12-29 Immunogenetics www.ncbi.nlm.nih.gov/pubmed/22205395 Genome-wide associated loci influencing interleukin (IL)-10, IL-1Ra, and IL-6 levels in African Americans. Interleukin-6 levels 697 African American individuals NA Affymetrix [5396780] (imputed) 20 interleukin-6 measurement http://www.ebi.ac.uk/efo/EFO_0004810 GCST006103 Genome-wide genotyping array 697 2018-08-16 22205395 Tekola Ayele F 2011-12-29 Immunogenetics www.ncbi.nlm.nih.gov/pubmed/22205395 Genome-wide associated loci influencing interleukin (IL)-10, IL-1Ra, and IL-6 levels in African Americans. Interleukin-1-receptor antagonist levels 706 African American individuals NA Affymetrix [5396780] (imputed) 7 interleukin 1 receptor antagonist measurement http://www.ebi.ac.uk/efo/EFO_0004754 GCST006104 Genome-wide genotyping array 706 2018-03-16 29343764 Jiang X 2018-01-17 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29343764 Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. Vitamin D levels (dietary vitamin D intake interaction) 39,868 European ancestry individuals 2,113 European ancestry individuals Affymetrix, Illumina [at least 1200000] (imputed) 5 vitamin D measurement, vitamin D dietary intake measurement http://www.ebi.ac.uk/efo/EFO_0004631, http://www.ebi.ac.uk/efo/EFO_0008539 GCST005366 Genome-wide genotyping array 39868 2018-03-16 29343764 Jiang X 2018-01-17 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29343764 Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. Vitamin D levels 79,366 European ancestry individuals 42,757 European and unknown ancestry individuals Affymetrix, Illumina [up to 3600000] (imputed) 6 vitamin D measurement http://www.ebi.ac.uk/efo/EFO_0004631 GCST005367 Genome-wide genotyping array 79366 2018-09-06 29315502 Tamraz B 2018-01-09 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/29315502 A Genome-Wide Association Study Identifies a Candidate Gene Associated With Atazanavir Exposure Measured in Hair. Atazanavir levels 64 European ancestry women, 194 African American women, 130 Hispanic women, 10 women 79 women Illumina [~ 14000000] (imputed) 1 atazanavir measurement http://www.ebi.ac.uk/efo/EFO_0009306 GCST006203 Genome-wide genotyping array 398 2017-02-25 27418160 van 't Hof FN 2016-07-14 J Am Heart Assoc www.ncbi.nlm.nih.gov/pubmed/27418160 Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms. Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy) 1,516 European ancestry intracranial aneurysm cases, 818 European ancestry abdominal aortic aneurysm cases, 760 European ancestry thoracic aortic aneurysm cases, 9,507 European ancestry controls NA Illumina [9245988] (imputed) 4 thoracic aortic aneurysm, Abdominal Aortic Aneurysm, brain aneurysm http://www.ebi.ac.uk/efo/EFO_0004282, http://www.ebi.ac.uk/efo/EFO_0004214, http://www.ebi.ac.uk/efo/EFO_0003870 GCST003683 Genome-wide genotyping array 12601 2017-02-03 27412012 Lamina C 2016-07-12 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/27412012 A genome-wide association meta-analysis on apolipoprotein A-IV concentrations. Apolipoprotein A-IV levels 13,813 European ancestry individuals 2,267 European ancestry individuals Affymetrix, Illumina [at least 7000000] (imputed) 4 apolipoprotein A-IV measurement http://www.ebi.ac.uk/efo/EFO_0007848 GCST003590 Genome-wide genotyping array 13813 2017-12-05 28990592 Warrington NM 2017-10-09 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/28990592 Maternal and fetal genetic contribution to gestational weight gain. Early gestational weight gain (fetal effect) up to 8,559 European ancestry fetuses up to 3,289 European ancestry fetuses Affymetrix, Illumina [NR] (imputed) 0 early gestational weight gain, fetal genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0008437, http://www.ebi.ac.uk/efo/EFO_0007959 GCST005032 Genome-wide genotyping array 8559 2017-12-05 28990592 Warrington NM 2017-10-09 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/28990592 Maternal and fetal genetic contribution to gestational weight gain. Gestational weight gain (fetal effect) up to 16,434 European ancestry fetuses up to 7,827 European ancestry fetuses Affymetrix, Illumina [NR] (imputed) 0 fetal genotype effect measurement, gestational weight gain measurement http://www.ebi.ac.uk/efo/EFO_0007959, http://www.ebi.ac.uk/efo/EFO_0008435 GCST005031 Genome-wide genotyping array 16434 2017-12-05 28990592 Warrington NM 2017-10-09 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/28990592 Maternal and fetal genetic contribution to gestational weight gain. Late gestational weight gain (fetal effect) up to 8,641 European ancestry fetuses up to 779 European ancestry fetuses Affymetrix, Illumina [NR] (imputed) 0 fetal genotype effect measurement, late gestational weight gain http://www.ebi.ac.uk/efo/EFO_0007959, http://www.ebi.ac.uk/efo/EFO_0008436 GCST005030 Genome-wide genotyping array 8641 2017-12-05 28990592 Warrington NM 2017-10-09 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/28990592 Maternal and fetal genetic contribution to gestational weight gain. Early gestation weight gain (maternal effect) up to 7,704 European ancestry mothers up to 1,584 European ancestry mothers Affymetrix, Illumina [NR] (imputed) 0 early gestational weight gain http://www.ebi.ac.uk/efo/EFO_0008437 GCST005029 Genome-wide genotyping array 7704 2017-12-05 28990592 Warrington NM 2017-10-09 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/28990592 Maternal and fetal genetic contribution to gestational weight gain. Late gestational weight gain (maternal effect) up to 7,681 European ancestry mothers up to 1,646 European ancestry mothers Affymetrix, Illumina [NR] (imputed) 0 late gestational weight gain http://www.ebi.ac.uk/efo/EFO_0008436 GCST005034 Genome-wide genotyping array 7681 2017-12-05 28990592 Warrington NM 2017-10-09 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/28990592 Maternal and fetal genetic contribution to gestational weight gain. Gestational weight gain (maternal effect) up to 10,555 European ancestry mothers up to 11280 European ancestry mothers Affymetrix, Illumina [NR] (imputed) 0 gestational weight gain measurement http://www.ebi.ac.uk/efo/EFO_0008435 GCST005033 Genome-wide genotyping array 10555 2017-12-20 29109912 Rawofi L 2017-11-02 PeerJ www.ncbi.nlm.nih.gov/pubmed/29109912 Genome-wide association study of pigmentary traits (skin and iris color) in individuals of East Asian ancestry. Iris color (b* coordinate) 377 East Asian ancestry individuals NA Illumina [at least 520076] (imputed) 7 eye color http://www.ebi.ac.uk/efo/EFO_0003949 GCST005096 Genome-wide genotyping array 377 2017-12-20 29109912 Rawofi L 2017-11-02 PeerJ www.ncbi.nlm.nih.gov/pubmed/29109912 Genome-wide association study of pigmentary traits (skin and iris color) in individuals of East Asian ancestry. Iris heterochromicity 377 East Asian ancestry individuals NA Illumina [at least 520076] (imputed) 6 eye color http://www.ebi.ac.uk/efo/EFO_0003949 GCST005095 Genome-wide genotyping array 377 2017-12-20 29109912 Rawofi L 2017-11-02 PeerJ www.ncbi.nlm.nih.gov/pubmed/29109912 Genome-wide association study of pigmentary traits (skin and iris color) in individuals of East Asian ancestry. Skin pigmentation 377 East Asian ancestry individuals 568 East Asian ancestry individuals Illumina [at least 520076] (imputed) 0 skin pigmentation measurement http://www.ebi.ac.uk/efo/EFO_0007009 GCST005084 Genome-wide genotyping array 377 2017-12-20 29109912 Rawofi L 2017-11-02 PeerJ www.ncbi.nlm.nih.gov/pubmed/29109912 Genome-wide association study of pigmentary traits (skin and iris color) in individuals of East Asian ancestry. Iris color (L* coordinate) 377 East Asian ancestry individuals NA Illumina [at least 520076] (imputed) 14 eye color http://www.ebi.ac.uk/efo/EFO_0003949 GCST005094 Genome-wide genotyping array 377 2017-12-20 29109912 Rawofi L 2017-11-02 PeerJ www.ncbi.nlm.nih.gov/pubmed/29109912 Genome-wide association study of pigmentary traits (skin and iris color) in individuals of East Asian ancestry. Iris color (a* coordinate) 377 East Asian ancestry individuals NA Illumina [at least 520076] (imputed) 9 eye color http://www.ebi.ac.uk/efo/EFO_0003949 GCST005093 Genome-wide genotyping array 377 2018-01-16 29168253 Seielstad M 2017-11-22 Transfusion www.ncbi.nlm.nih.gov/pubmed/29168253 Genomewide association study of HLA alloimmunization in previously pregnant blood donors. Alloimmunization response to pregnancy (HLA class I and II) up to 193 European ancestry alloantibody-positive previously pregnant cases, 753 European ancestry alloantibody-negative previously pregnant controls NA Illumina [9427497] (imputed) 0 pregnancy induced alloimmunization http://www.ebi.ac.uk/efo/EFO_0008462 GCST005154 Genome-wide genotyping array 946 2018-01-16 29168253 Seielstad M 2017-11-22 Transfusion www.ncbi.nlm.nih.gov/pubmed/29168253 Genomewide association study of HLA alloimmunization in previously pregnant blood donors. Alloimmunization response to pregnancy (HLA class I) up to 247 European ancestry alloantibody-positive previously pregnant cases, 753 European ancestry alloantibody-negative previously pregnant controls NA Illumina [9427497] (imputed) 2 pregnancy induced alloimmunization http://www.ebi.ac.uk/efo/EFO_0008462 GCST005156 Genome-wide genotyping array 1000 2018-01-16 29168253 Seielstad M 2017-11-22 Transfusion www.ncbi.nlm.nih.gov/pubmed/29168253 Genomewide association study of HLA alloimmunization in previously pregnant blood donors. Alloimmunization response to pregnancy (HLA class II) up to 332 European ancestry alloantibody-positive previously pregnant cases, 753 European ancestry alloantibody-negative previously pregnant controls NA Illumina [9427497] (imputed) 0 pregnancy induced alloimmunization http://www.ebi.ac.uk/efo/EFO_0008462 GCST005157 Genome-wide genotyping array 1085 2018-01-16 29168253 Seielstad M 2017-11-22 Transfusion www.ncbi.nlm.nih.gov/pubmed/29168253 Genomewide association study of HLA alloimmunization in previously pregnant blood donors. Alloimmunization response to pregnancy 752 European ancestry alloantibody-positive previously pregnant cases, 753 European ancestry alloantibody-negative previously pregnant controls NA Illumina [9427497] (imputed) 0 pregnancy induced alloimmunization http://www.ebi.ac.uk/efo/EFO_0008462 GCST005155 Genome-wide genotyping array 1505 2017-09-14 28672053 Meng W 2017-07-03 Br J Dermatol www.ncbi.nlm.nih.gov/pubmed/28672053 A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers. Foot ulcer in diabetes and neuropathy 662 European ancestry type 2 diabetes cases, 37 European ancestry type 1 diabetes cases, 2,584 European ancestry type 2 diabetes controls, 111 European ancestry type 1 diabetes controls NA Affymetrix, Illumina [6706850] (imputed) 2 diabetic foot http://www.ebi.ac.uk/efo/EFO_1001459 GCST004724 Genome-wide genotyping array 3400 2017-09-14 28672053 Meng W 2017-07-03 Br J Dermatol www.ncbi.nlm.nih.gov/pubmed/28672053 A genome-wide association study suggests that MAPK14 is associated with diabetic foot ulcers. Foot ulcer and neuropathy in diabetes 662 European ancestry type 2 diabetes and neuropathy cases, 37 European ancestry type 1 diabetes and neuropathy cases, 4,250 European ancestry type 1 and type 2 diabetes controls NA Affymetrix, Illumina [6706850] (imputed) 3 diabetic foot, neuropathy http://www.ebi.ac.uk/efo/EFO_1001459, http://www.ebi.ac.uk/efo/EFO_0004149 GCST004725 Genome-wide genotyping array 4955 2018-01-05 29187746 Howard DM 2017-11-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29187746 Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank. Major depressive disorder 2,605 European ancestry cases, 16,168 European ancestry controls 8,508 European ancestry cases, 16,527 European ancestry controls Illumina [at least 2618094] (imputed) 3 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST005108 Genome-wide genotyping array 18773 2018-02-02 29187730 Ward J 2017-11-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29187730 Genome-wide analysis in UK Biobank identifies four loci associated with mood instability and genetic correlation with major depressive disorder, anxiety disorder and schizophrenia. Mood instability 53,525 European ancestry cases, 60,443 European ancestry controls NA Affymetrix [8797848] (imputed) 4 mood instability measurement http://www.ebi.ac.uk/efo/EFO_0008475 GCST005238 Genome-wide genotyping array 113968 2018-02-02 29187730 Ward J 2017-11-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29187730 Genome-wide analysis in UK Biobank identifies four loci associated with mood instability and genetic correlation with major depressive disorder, anxiety disorder and schizophrenia. Mood instability 43,660 European ancestry cases without a psychiatric disorder diagnosis, 60,443 European ancestry controls NA Affymetrix [8797848] (imputed) 4 mood instability measurement http://www.ebi.ac.uk/efo/EFO_0008475 GCST005237 Genome-wide genotyping array 104103 2018-07-09 29325096 Eriksson AL 2018-01-09 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/29325096 Genetic Determinants of Circulating Estrogen Levels, and Evidence of a Causal Effect of Estradiol on Bone Density in Men. Estradiol levels 11,097 European ancestry men NA Affymetrix, Illumina [~ 2500000] (imputed) 1 estradiol measurement http://www.ebi.ac.uk/efo/EFO_0004697 GCST005828 Genome-wide genotyping array 11097 2018-07-09 29325096 Eriksson AL 2018-01-09 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/29325096 Genetic Determinants of Circulating Estrogen Levels, and Evidence of a Causal Effect of Estradiol on Bone Density in Men. Estrone levels 7,570 European ancestry men NA Affymetrix, Illumina [~ 2500000] (imputed) 4 estrone measurement http://www.ebi.ac.uk/efo/EFO_0007970 GCST005827 Genome-wide genotyping array 7570 2018-03-08 26366551 Zoledziewska M 2015-11-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26366551 Height-reducing variants and selection for short stature in Sardinia. Height 6,307 Sardinian (founder/population isolate) individuals 5,314 Sardinian (founder/population isolate) individuals, 19,053 European ancestry individuals Illumina [11826948] (imputed) 0 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST005354 Genome-wide genotyping array 6307 2017-02-02 27515689 Kerns SL 2016-07-20 EBioMedicine www.ncbi.nlm.nih.gov/pubmed/27515689 Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer. Response to radiotherapy in prostate cancer (toxicity, urinary frequency) 1,409 European ancestry individuals NA NR [~ 38000000] (imputed) 11 response to radiation http://purl.obolibrary.org/obo/GO_0009314 GCST003582 Genome-wide genotyping array 1409 2017-02-02 27515689 Kerns SL 2016-07-20 EBioMedicine www.ncbi.nlm.nih.gov/pubmed/27515689 Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer. Toxicity response to radiotherapy in prostate cancer (decreased urine stream) (time to event) 1,245 European ancestry individuals NA NR [~ 38000000] (imputed) 8 response to radiation http://purl.obolibrary.org/obo/GO_0009314 GCST003581 Genome-wide genotyping array 1245 2017-02-02 27515689 Kerns SL 2016-07-20 EBioMedicine www.ncbi.nlm.nih.gov/pubmed/27515689 Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer. Response to radiotherapy in prostate cancer (overall toxicity) 1,346 European ancestry individuals NA NR [~ 38000000] (imputed) 16 response to radiation http://purl.obolibrary.org/obo/GO_0009314 GCST003583 Genome-wide genotyping array 1346 2017-02-02 27515689 Kerns SL 2016-07-20 EBioMedicine www.ncbi.nlm.nih.gov/pubmed/27515689 Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer. Response to radiotherapy in prostate cancer (toxicity, rectal bleeding) 1,487 European ancestry individuals NA NR [~ 38000000] (imputed) 6 response to radiation http://purl.obolibrary.org/obo/GO_0009314 GCST003584 Genome-wide genotyping array 1487 2017-09-28 28835685 Yamashiro K 2017-08-23 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28835685 A prospective multicenter study on genome wide associations to ranibizumab treatment outcome for age-related macular degeneration. Response to ranibizumab in age-related macular degeneration (visual acuity) 256 Japanese ancestry treated individuals 205 Japanese ancestry treated individuals Illumina [8480849] (imputed) 0 visual acuity measurement, response to ranibizumab http://www.ebi.ac.uk/efo/EFO_0008385, http://www.ebi.ac.uk/efo/EFO_0008348 GCST004801 Genome-wide genotyping array 256 2017-09-28 28835685 Yamashiro K 2017-08-23 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28835685 A prospective multicenter study on genome wide associations to ranibizumab treatment outcome for age-related macular degeneration. Response to ranibizumab in age-related macular degeneration (additional treatment requirement) 256 Japanese ancestry treated individuals 205 Japanese ancestry treated individuals Illumina [8480849] (imputed) 0 response to ranibizumab, treatment outcome measurement http://www.ebi.ac.uk/efo/EFO_0008348, http://www.ebi.ac.uk/efo/EFO_0008383 GCST004803 Genome-wide genotyping array 256 2017-09-28 28835685 Yamashiro K 2017-08-23 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28835685 A prospective multicenter study on genome wide associations to ranibizumab treatment outcome for age-related macular degeneration. Response to ranibizumab in age-related macular degeneration (dry maculae) 256 Japanese ancestry treated individuals 205 Japanese ancestry treated individuals Illumina [8480849] (imputed) 0 response to ranibizumab, macula measurement http://www.ebi.ac.uk/efo/EFO_0008348, http://www.ebi.ac.uk/efo/EFO_0008375 GCST004802 Genome-wide genotyping array 256 2018-03-01 29331962 Kochi Y 2018-01-13 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/29331962 Splicing variant of WDFY4 augments MDA5 signalling and the risk of clinically amyopathic dermatomyositis. Idiopathic inflammatory myopathy 576 Japanese ancestry cases, 6,270 East Asian controls NA Illumina [496819] 0 myositis http://www.ebi.ac.uk/efo/EFO_0000783 GCST005341 Genome-wide genotyping array 6846 2018-03-01 29331962 Kochi Y 2018-01-13 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/29331962 Splicing variant of WDFY4 augments MDA5 signalling and the risk of clinically amyopathic dermatomyositis. Polymyositis 236 Japanese ancestry cases, 6,270 East Asian ancestry controls NA Illumina [496819] 0 polymyositis http://www.ebi.ac.uk/efo/EFO_0003063 GCST005340 Genome-wide genotyping array 6506 2018-03-01 29331962 Kochi Y 2018-01-13 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/29331962 Splicing variant of WDFY4 augments MDA5 signalling and the risk of clinically amyopathic dermatomyositis. Dermatomyositis 340 Japanese ancestry cases, 6,270 East Asian ancestry controls NA Illumina [496819] 0 dermatomyositis http://www.ebi.ac.uk/efo/EFO_0000398 GCST005339 Genome-wide genotyping array 6610 2018-03-01 29331962 Kochi Y 2018-01-13 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/29331962 Splicing variant of WDFY4 augments MDA5 signalling and the risk of clinically amyopathic dermatomyositis. Clinically amyopathic dermatomyositis 33 Japanese ancestry cases, 6,270 East Asian ancestry controls 21 European ancestry cases, 84 European ancestry controls Illumina [496819] 1 clinically amyopathic dermatomyositis http://www.ebi.ac.uk/efo/EFO_0008532 GCST005338 Genome-wide genotyping array 6303 2018-01-30 24699409 Prokopenko I 2014-04-03 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/24699409 A central role for GRB10 in regulation of islet function in man. Insulin sensitivity index up to 4,565 European individuals, up to 413 Old Order Amish (founder/genetic isolate) individuals 20,514 non-diabetic individuals Affymetrix, Illumina [at least 1961018] (imputed) 1 insulin sensitivity measurement http://www.ebi.ac.uk/efo/EFO_0004471 GCST005221 Genome-wide genotyping array 4978 2018-01-30 24699409 Prokopenko I 2014-04-03 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/24699409 A central role for GRB10 in regulation of islet function in man. Insulin levels up to 4,483 European individuals, up to 441 Old Order Amish (founder/genetic isolate) individuals 20,792 European individuals Affymetrix, Illumina [at least 1961018] (imputed) 2 insulin measurement http://www.ebi.ac.uk/efo/EFO_0004467 GCST005220 Genome-wide genotyping array 4924 2018-01-30 24699409 Prokopenko I 2014-04-03 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/24699409 A central role for GRB10 in regulation of islet function in man. Insulin levels adjusted for BMI up to 4,409 European individuals, up to 411 Old Order Amish (founder/genetic isolate) individuals 18,535 European individuals Affymetrix, Illumina [at least 1961018] (imputed) 4 insulin response measurement http://www.ebi.ac.uk/efo/EFO_0008473 GCST005217 Genome-wide genotyping array 4820 2018-01-30 24699409 Prokopenko I 2014-04-03 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/24699409 A central role for GRB10 in regulation of islet function in man. Insulin disposition index up to 4,746 European individuals, up to 412 Old Order Amish (founder/genetic isolate) individuals 20,461 European individuals Affymetrix, Illumina [at least 1961018] (imputed) 4 disposition index measurement http://www.ebi.ac.uk/efo/EFO_0006832 GCST005222 Genome-wide genotyping array 5158 2018-01-30 24699409 Prokopenko I 2014-04-03 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/24699409 A central role for GRB10 in regulation of islet function in man. Ratio of the area under the curve for insulin and the area under the curve for glucose up to 4,231 European individuals, up to 413 Old Order Amish (founder/genetic isolate) individuals 20,513 European individuals Affymetrix, Illumina [at least 1961018] (imputed) 1 insulin response measurement http://www.ebi.ac.uk/efo/EFO_0008473 GCST005223 Genome-wide genotyping array 4644 2018-01-30 24699409 Prokopenko I 2014-04-03 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/24699409 A central role for GRB10 in regulation of islet function in man. Area under the curve of insulin levels up to 4,324 European individuals, up to 413 Old Order Amish (founder/genetic isolate) individuals 20,620 European individuals Affymetrix, Illumina [at least 1961018] (imputed) 2 insulin response measurement http://www.ebi.ac.uk/efo/EFO_0008473 GCST005218 Genome-wide genotyping array 4737 2018-01-30 24699409 Prokopenko I 2014-04-03 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/24699409 A central role for GRB10 in regulation of islet function in man. Incremental insulin up to 4,447 European individuals, up to 411 Old Order Amish (founder/genetic isolate) individuals 20,706 European individuals NR [at least 1961018] (imputed) 3 insulin measurement http://www.ebi.ac.uk/efo/EFO_0004467 GCST005219 Genome-wide genotyping array 4858 2018-01-30 24699409 Prokopenko I 2014-04-03 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/24699409 A central role for GRB10 in regulation of islet function in man. Corrected insulin response up to 4,961 European individuals, up to 411 Old Order Amish (founder/genetic isolate) individuals 20,722 European individuals Affymetrix, Illumina [at least 1961018] (imputed) 6 insulin response measurement http://www.ebi.ac.uk/efo/EFO_0008473 GCST005215 Genome-wide genotyping array 5372 2018-01-30 24699409 Prokopenko I 2014-04-03 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/24699409 A central role for GRB10 in regulation of islet function in man. Corrected insulin response adjusted for insulin sensitivity index up to 4,565 European individuals, up to 413 Old Order Amish (founder/genetic isolate) individuals 20,461 European individuals Affymetrix, Illumina [at least 1961018] (imputed) 6 insulin sensitivity measurement, insulin response measurement http://www.ebi.ac.uk/efo/EFO_0004471, http://www.ebi.ac.uk/efo/EFO_0008473 GCST005216 Genome-wide genotyping array 4978 2019-02-26 30500874 Kakuta Y 2018-11-29 J Crohns Colitis www.ncbi.nlm.nih.gov/pubmed/30500874 A genome-wide association study identifying RAP1A as a novel susceptibility gene for Crohn's disease in Japanese individuals. Crohn's disease 713 Japanese ancestry cases, 2,083 Japanese ancestry controls 770 Japanese ancestry cases, 852 Japanese ancestry controls NR [4335144] (imputed) 9 Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000384 GCST007216 Genome-wide genotyping array 2796 2019-02-12 30412241 Takeuchi F 2018-11-09 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30412241 Genome-wide association study of cervical cancer suggests a role for ARRDC3 gene in human papillomavirus infection. Cervical cancer 2,609 East Asian ancestry cases, 4,712 East Asian ancestry controls 1,461 Han Chinese ancestry cases, 3,295 Han Chinese ancestry controls Affymetrix, Illumina [4602429] (imputed) 5 cervical carcinoma http://www.ebi.ac.uk/efo/EFO_0001061 GCST007119 Genome-wide genotyping array 7321 2019-08-29 30958311 Tao F 2019-04-03 J Neuromuscul Dis www.ncbi.nlm.nih.gov/pubmed/30958311 Modifier Gene Candidates in Charcot-Marie-Tooth Disease Type 1A: A Case-Only Genome-Wide Association Study. Decreased fine motor function in Charcot-Marie-Tooth disease 1A (eating with utensils) 132 European ancestry severe cases, 288 European ancestry mild cases NA Illumina [600000] 1 decreased fine motor function http://www.ebi.ac.uk/efo/EFO_0010132 GCST008533 Genome-wide genotyping array 420 2019-08-29 30958311 Tao F 2019-04-03 J Neuromuscul Dis www.ncbi.nlm.nih.gov/pubmed/30958311 Modifier Gene Candidates in Charcot-Marie-Tooth Disease Type 1A: A Case-Only Genome-Wide Association Study. Hearing loss in Charcot-Marie-Tooth disease 1A 61 European ancestry severe cases, 303 European ancestry mild cases NA Illumina [600000] 1 hearing loss http://www.ebi.ac.uk/efo/EFO_0004238 GCST008534 Genome-wide genotyping array 364 2019-08-29 30958311 Tao F 2019-04-03 J Neuromuscul Dis www.ncbi.nlm.nih.gov/pubmed/30958311 Modifier Gene Candidates in Charcot-Marie-Tooth Disease Type 1A: A Case-Only Genome-Wide Association Study. Decreased sensory function in Charcot-Marie-Tooth disease type 1A 308 European ancestry severe cases, 112 European ancestry mild cases NA Illumina [600000] 1 Somatic sensory dysfunction http://purl.obolibrary.org/obo/HP_0003474 GCST008537 Genome-wide genotyping array 420 2019-08-29 30958311 Tao F 2019-04-03 J Neuromuscul Dis www.ncbi.nlm.nih.gov/pubmed/30958311 Modifier Gene Candidates in Charcot-Marie-Tooth Disease Type 1A: A Case-Only Genome-Wide Association Study. Neuropathy in Charcot-Marie-Tooth disease type 1A 471 European ancestry individuals NA Illumina [600000] 1 neuropathy http://www.ebi.ac.uk/efo/EFO_0004149 GCST008530 Genome-wide genotyping array 471 2019-08-29 30958311 Tao F 2019-04-03 J Neuromuscul Dis www.ncbi.nlm.nih.gov/pubmed/30958311 Modifier Gene Candidates in Charcot-Marie-Tooth Disease Type 1A: A Case-Only Genome-Wide Association Study. Balance difficulty in Charcot-Marie-Tooth disease type 1A 352 European ancestry severe cases, 61 European ancestry mild cases NA Illumina [600000] 1 Gait imbalance http://purl.obolibrary.org/obo/HP_0002141 GCST008538 Genome-wide genotyping array 413 2019-08-29 30958311 Tao F 2019-04-03 J Neuromuscul Dis www.ncbi.nlm.nih.gov/pubmed/30958311 Modifier Gene Candidates in Charcot-Marie-Tooth Disease Type 1A: A Case-Only Genome-Wide Association Study. Decreased fine motor function in Charcot-Marie-Tooth disease 1A (buttons, zippers, fasteners, bottles) 277 European ancestry severe cases, 146 European ancestry mild cases NA Illumina [600000] 1 decreased fine motor function http://www.ebi.ac.uk/efo/EFO_0010132 GCST008540 Genome-wide genotyping array 423 2019-08-29 30958311 Tao F 2019-04-03 J Neuromuscul Dis www.ncbi.nlm.nih.gov/pubmed/30958311 Modifier Gene Candidates in Charcot-Marie-Tooth Disease Type 1A: A Case-Only Genome-Wide Association Study. Walking difficulty in Charcot-Marie-Tooth disease 1A 362 European ancestry severe cases, 62 European ancestry mild cases NA Illumina [600000] 1 decreased walking ability http://www.ebi.ac.uk/efo/EFO_0010131 GCST008543 Genome-wide genotyping array 424 2019-08-29 30958311 Tao F 2019-04-03 J Neuromuscul Dis www.ncbi.nlm.nih.gov/pubmed/30958311 Modifier Gene Candidates in Charcot-Marie-Tooth Disease Type 1A: A Case-Only Genome-Wide Association Study. Reduced foot dorsiflexion strength in Charcot-Marie-Tooth disease type 1A 174 European ancestry severe cases, 117 European ancestry mild cases NA Illumina [600000] 0 foot muscle strength measurement http://www.ebi.ac.uk/efo/EFO_0009699 GCST008544 Genome-wide genotyping array 291 2019-08-29 30958311 Tao F 2019-04-03 J Neuromuscul Dis www.ncbi.nlm.nih.gov/pubmed/30958311 Modifier Gene Candidates in Charcot-Marie-Tooth Disease Type 1A: A Case-Only Genome-Wide Association Study. First dorsal interosseous strength in Charcot-Marie-Tooth disease 1A 120 European ancestry severe cases, 80 European ancestry mild cases NA Illumina [600000] 0 foot muscle strength measurement http://www.ebi.ac.uk/efo/EFO_0009699 GCST008542 Genome-wide genotyping array 200 2019-08-29 30958311 Tao F 2019-04-03 J Neuromuscul Dis www.ncbi.nlm.nih.gov/pubmed/30958311 Modifier Gene Candidates in Charcot-Marie-Tooth Disease Type 1A: A Case-Only Genome-Wide Association Study. Foot deformity in Charcot-Marie-Tooth disease 1A 368 European ancestry severe cases, 49 European ancestry mild cases NA Illumina [600000] 1 Abnormal foot morphology http://purl.obolibrary.org/obo/HP_0001760 GCST008541 Genome-wide genotyping array 417 2019-08-29 30958311 Tao F 2019-04-03 J Neuromuscul Dis www.ncbi.nlm.nih.gov/pubmed/30958311 Modifier Gene Candidates in Charcot-Marie-Tooth Disease Type 1A: A Case-Only Genome-Wide Association Study. Foot plantar flexion strength in Charcot-Marie-Tooth disease 1A 136 European ancestry severe cases, 276 European ancestry mild cases NA Illumina [600000] 1 foot muscle strength measurement http://www.ebi.ac.uk/efo/EFO_0009699 GCST008539 Genome-wide genotyping array 412 2019-08-29 30958311 Tao F 2019-04-03 J Neuromuscul Dis www.ncbi.nlm.nih.gov/pubmed/30958311 Modifier Gene Candidates in Charcot-Marie-Tooth Disease Type 1A: A Case-Only Genome-Wide Association Study. Scoliosis in Charcot-Marie-Tooth disease 1A 91 European ancestry severe cases, 318 European ancestry mild cases NA Illumina [600000] 1 scoliosis http://www.ebi.ac.uk/efo/EFO_0004273 GCST008536 Genome-wide genotyping array 409 2019-08-29 30958311 Tao F 2019-04-03 J Neuromuscul Dis www.ncbi.nlm.nih.gov/pubmed/30958311 Modifier Gene Candidates in Charcot-Marie-Tooth Disease Type 1A: A Case-Only Genome-Wide Association Study. Arthritic-like pain in Charcot-Marie-Tooth type 1A 197 European ancestry severe cases, 212 European ancestry mild cases NA Illumina [600000] 0 pain http://www.ebi.ac.uk/efo/EFO_0003843 GCST008535 Genome-wide genotyping array 409 2019-08-29 30958311 Tao F 2019-04-03 J Neuromuscul Dis www.ncbi.nlm.nih.gov/pubmed/30958311 Modifier Gene Candidates in Charcot-Marie-Tooth Disease Type 1A: A Case-Only Genome-Wide Association Study. Burning or tingling in extremities in Charcot-Marie-Tooth disease type 1A 141 European ancestry severe cases, 265 European ancestry mild cases NA Illumina [600000] 1 disturbance of skin sensation http://www.ebi.ac.uk/efo/EFO_0009522 GCST008532 Genome-wide genotyping array 406 2019-07-05 31152163 Wuttke M 2019-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31152163 A catalog of genetic loci associated with kidney function from analyses of a million individuals. Estimated glomerular filtration rate 567,460 European ancestry individuals, 165,726 East Asian ancestry individuals, 13,842 African American individuals, 13,359 South Asian ancestry individuals, 4,961 Hispanic individuals 216,518 European ancestry individuals, 64,204 non-Hispanic black individuals Affymetrix, Illumina [8221591] (imputed) 307 glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0005208 GCST008058 Genome-wide genotyping array 765348 2019-07-05 31152163 Wuttke M 2019-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31152163 A catalog of genetic loci associated with kidney function from analyses of a million individuals. Estimated glomerular filtration rate 567,460 European ancestry individuals 216,518 European ancestry individuals Affymetrix, Illumina [8834748] (imputed) 256 glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0005208 GCST008059 Genome-wide genotyping array 567460 2019-07-05 31152163 Wuttke M 2019-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31152163 A catalog of genetic loci associated with kidney function from analyses of a million individuals. Estimated glomerular filtration rate 165,726 East Asian ancestry individuals NA Affymetrix, Illumina [8221591] (imputed) 45 glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0005208 GCST008060 Genome-wide genotyping array 165726 2019-07-05 31152163 Wuttke M 2019-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31152163 A catalog of genetic loci associated with kidney function from analyses of a million individuals. Estimated glomerular filtration rate 13,359 South Asian ancestry individuals NA Affymetrix, Illumina [8221591] (imputed) 3 glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0005208 GCST008061 Genome-wide genotyping array 13359 2019-07-05 31152163 Wuttke M 2019-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31152163 A catalog of genetic loci associated with kidney function from analyses of a million individuals. Blood urea nitrogen levels 416,178 European and unknown ancestry individuals NA Affymetrix, Illumina [8176554] (imputed) 132 blood urea nitrogen measurement http://www.ebi.ac.uk/efo/EFO_0004741 GCST008062 Genome-wide genotyping array 416178 2019-07-05 31152163 Wuttke M 2019-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31152163 A catalog of genetic loci associated with kidney function from analyses of a million individuals. Blood urea nitrogen levels 243,029 European ancestry individuals NA Affymetrix, Illumina [8358347] (imputed) 0 blood urea nitrogen measurement http://www.ebi.ac.uk/efo/EFO_0004741 GCST008063 Genome-wide genotyping array 243029 2019-07-05 31152163 Wuttke M 2019-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31152163 A catalog of genetic loci associated with kidney function from analyses of a million individuals. Chronic kidney disease 64,164 European and unknown ancestry cases, 561,055 European and unknown ancestry controls NA Affymetrix, Illumina [9585923] (imputed) 47 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST008064 Genome-wide genotyping array 625219 2019-07-05 31152163 Wuttke M 2019-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31152163 A catalog of genetic loci associated with kidney function from analyses of a million individuals. Chronic kidney disease up to 64,164 European ancestry cases, up to 561,055 European ancestry controls NA Affymetrix, Illumina [9585923] (imputed) 0 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST008065 Genome-wide genotyping array 625219 2019-07-05 31152163 Wuttke M 2019-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31152163 A catalog of genetic loci associated with kidney function from analyses of a million individuals. Estimated glomerular filtration rate 13,842 African American individuals NA Affymetrix, Illumina [8221591] (imputed) 0 glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0005208 GCST008066 Genome-wide genotyping array 13842 2019-08-30 31264924 Meng W 2019-07-02 Ophthalmic Genet www.ncbi.nlm.nih.gov/pubmed/31264924 A genome-wide association study implicates that the TTC39C gene is associated with diabetic maculopathy with decreased visual acuity. Diabetic maculopathy with decreased visual acuity in type 2 diabetes 469 Scottish ancestry cases, 1,374 Scottish ancestry controls NA Affymetrix, Illumina [6717712] (imputed) 2 visual acuity measurement, diabetic maculopathy http://www.ebi.ac.uk/efo/EFO_0008385, http://www.ebi.ac.uk/efo/EFO_0010133 GCST008545 Genome-wide genotyping array 1843 2019-08-30 31264924 Meng W 2019-07-02 Ophthalmic Genet www.ncbi.nlm.nih.gov/pubmed/31264924 A genome-wide association study implicates that the TTC39C gene is associated with diabetic maculopathy with decreased visual acuity. Diabetic maculopathy in type 2 diabetes 1,240 Scottish ancestry cases, 1,374 Scottish ancestry controls NA Affymetrix, Illumina [6717712] (imputed) 8 diabetic maculopathy http://www.ebi.ac.uk/efo/EFO_0010133 GCST008546 Genome-wide genotyping array 2614 2019-08-19 31268507 Periyasamy S 2019-07-03 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/31268507 Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study. Schizophrenia 816 Indian ancestry cases, 900 Indian ancestry controls, 505 Indian ancestry cases and 871 Indian ancestry controls from 405 families, up to 36,989 European and unknown ancestry cases, up to 113,075 European and unknown ancestry controls NA Illumina [up to 5582932] (imputed) 101 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST008459 Genome-wide genotyping array 153561 2019-08-12 31167214 Osazuwa-Peters OL 2019-06-05 Hum Hered www.ncbi.nlm.nih.gov/pubmed/31167214 The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions. Diastolic blood pressure x physical activity (least active quartile vs others) interaction (2df) 1,913 European ancestry inactive individuals, 4,792 European ancestry active individuals NA NR [2144169] (imputed) 3 diastolic blood pressure, physical activity http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0003940 GCST008412 Genome-wide genotyping array 6705 2019-08-12 31167214 Osazuwa-Peters OL 2019-06-05 Hum Hered www.ncbi.nlm.nih.gov/pubmed/31167214 The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions. Diastolic blood pressure x physical activity (less vs more active half) interaction (2df) 3,495 European ancestry inactive individuals, 3,210 European ancestry active individuals NA NR [2144141] (imputed) 5 diastolic blood pressure, physical activity http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0003940 GCST008411 Genome-wide genotyping array 6705 2019-08-12 31167214 Osazuwa-Peters OL 2019-06-05 Hum Hered www.ncbi.nlm.nih.gov/pubmed/31167214 The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions. Diastolic blood pressure x physical activity (least vs most active quartile) interaction (2df) 1,913 European ancestry inactive individuals, 2,071 European ancestry active individuals NA NR [2144462] (imputed) 5 diastolic blood pressure, physical activity http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0003940 GCST008410 Genome-wide genotyping array 3984 2019-08-12 31167214 Osazuwa-Peters OL 2019-06-05 Hum Hered www.ncbi.nlm.nih.gov/pubmed/31167214 The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions. Systolic blood pressure x physical activity (least active quartile vs others) interaction (2df) 1,913 European ancestry inactive individuals, 4,792 European ancestry active individuals NA NR [2144171] (imputed) 5 systolic blood pressure, physical activity http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0003940 GCST008409 Genome-wide genotyping array 6705 2019-08-12 31167214 Osazuwa-Peters OL 2019-06-05 Hum Hered www.ncbi.nlm.nih.gov/pubmed/31167214 The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions. Systolic blood pressure x physical activity (less vs more active half) interaction (2df) 3,495 European ancestry inactive individuals, 3,210 European ancestry active individuals NA NR [2144143] (imputed) 15 systolic blood pressure, physical activity http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0003940 GCST008408 Genome-wide genotyping array 6705 2019-08-12 31167214 Osazuwa-Peters OL 2019-06-05 Hum Hered www.ncbi.nlm.nih.gov/pubmed/31167214 The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions. Systolic blood pressure x physical activity (least vs most active quartile) interaction (2df) 1,913 European ancestry inactive individuals, 2,071 European ancestry active individuals NA NR [2144462] (imputed) 10 systolic blood pressure, physical activity http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0003940 GCST008402 Genome-wide genotyping array 3984 2019-08-08 31167214 Osazuwa-Peters OL 2019-06-05 Hum Hered www.ncbi.nlm.nih.gov/pubmed/31167214 The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions. Systolic blood pressure x physical activity interaction (2df) 6,705 European ancestry individuals NA NR [2144171] (imputed) 13 systolic blood pressure, physical activity measurement http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0008002 GCST008393 Genome-wide genotyping array 6705 2019-08-12 31167214 Osazuwa-Peters OL 2019-06-05 Hum Hered www.ncbi.nlm.nih.gov/pubmed/31167214 The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions. Diastolic blood pressure x physical activity (least active quartile vs others) interaction (1df) 1,913 European ancestry inactive individuals, 4,792 European ancestry active individuals NA NR [2144169] (imputed) 3 diastolic blood pressure, physical activity http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0003940 GCST008407 Genome-wide genotyping array 6705 2019-08-12 31167214 Osazuwa-Peters OL 2019-06-05 Hum Hered www.ncbi.nlm.nih.gov/pubmed/31167214 The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions. Diastolic blood pressure x physical activity (less vs more active half) interaction (1df) 3,495 European ancestry inactive individuals, 3,210 European ancestry active individuals NA NR [2144141] (imputed) 9 diastolic blood pressure, physical activity http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0003940 GCST008406 Genome-wide genotyping array 6705 2019-08-12 31167214 Osazuwa-Peters OL 2019-06-05 Hum Hered www.ncbi.nlm.nih.gov/pubmed/31167214 The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions. Diastolic blood pressure x physical activity (least vs most active quartile) interaction (1df) 1,913 European ancestry inactive individuals, 2,071 European ancestry active individuals NA NR [2144462] (imputed) 8 diastolic blood pressure, physical activity http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0003940 GCST008405 Genome-wide genotyping array 3984 2019-08-12 31167214 Osazuwa-Peters OL 2019-06-05 Hum Hered www.ncbi.nlm.nih.gov/pubmed/31167214 The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions. Systolic blood pressure x physical activity (least active quartile vs others) interaction (1df) 1,913 European ancestry inactive individuals, 4,792 European ancestry active individuals NA NR [2144171] (imputed) 6 systolic blood pressure, physical activity http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0003940 GCST008404 Genome-wide genotyping array 6705 2019-08-12 31167214 Osazuwa-Peters OL 2019-06-05 Hum Hered www.ncbi.nlm.nih.gov/pubmed/31167214 The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions. Systolic blood pressure x physical activity (less vs more active half) interaction (1df) 3,495 European ancestry inactive individuals, 3,210 European ancestry active individuals NA NR [2144143] (imputed) 9 systolic blood pressure, physical activity http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0003940 GCST008401 Genome-wide genotyping array 6705 2019-08-12 31167214 Osazuwa-Peters OL 2019-06-05 Hum Hered www.ncbi.nlm.nih.gov/pubmed/31167214 The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions. Systolic blood pressure x physical activity (least vs most active quartile) interaction (1df) 1,913 European ancestry inactive individuals, 2,071 European ancestry active individuals NA NR [2144462] (imputed) 8 systolic blood pressure, physical activity http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0003940 GCST008400 Genome-wide genotyping array 3984 2019-08-08 31167214 Osazuwa-Peters OL 2019-06-05 Hum Hered www.ncbi.nlm.nih.gov/pubmed/31167214 The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions. Systolic blood pressure x physical activity interaction (1df) 6,705 European ancestry individuals NA NR [2144171] (imputed) 9 systolic blood pressure, physical activity measurement http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0008002 GCST008392 Genome-wide genotyping array 6705 2019-08-08 31167214 Osazuwa-Peters OL 2019-06-05 Hum Hered www.ncbi.nlm.nih.gov/pubmed/31167214 The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions. Diastolic blood pressure x physical activity interaction (1df) 6,704 European ancestry individuals NA NR [2144169] (imputed) 13 diastolic blood pressure, physical activity measurement http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0008002 GCST008389 Genome-wide genotyping array 6704 2019-08-08 31167214 Osazuwa-Peters OL 2019-06-05 Hum Hered www.ncbi.nlm.nih.gov/pubmed/31167214 The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions. DIastolic blood pressure x physical activity interaction (2df) 6,704 European ancestry individuals NA NR [2144169] (imputed) 5 diastolic blood pressure, physical activity measurement http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0008002 GCST008390 Genome-wide genotyping array 6704 2019-09-05 31413261 Deelen J 2019-08-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31413261 A meta-analysis of genome-wide association studies identifies multiple longevity genes. Longevity (age >90th survival percentile) 11,262 European ancestry cases, 25,483 European ancestry controls 2,557 European ancestry cases, 4,987 European ancestry controls Affymetrix, Illumina [up to 10786384] (imputed) 2 longevity http://www.ebi.ac.uk/efo/EFO_0004300 GCST008598 Genome-wide genotyping array 36745 2019-09-05 31413261 Deelen J 2019-08-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31413261 A meta-analysis of genome-wide association studies identifies multiple longevity genes. Longevity (age >99th survival percentile) 3,484 European ancestry cases, 2,178 East Asian ancestry cases, 25,483 European ancestry controls, 2,299 East Asian ancestry controls NA Illumina [up to 9449311] (imputed) 7 longevity http://www.ebi.ac.uk/efo/EFO_0004300 GCST008601 Genome-wide genotyping array 33444 2019-09-05 31413261 Deelen J 2019-08-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31413261 A meta-analysis of genome-wide association studies identifies multiple longevity genes. Longevity (age >90th survival percentile) 11,262 European ancestry cases, 2,178 East Asian ancestry cases, 177 African American cases, 25,483 European ancestry controls, 2,299 East Asian ancestry controls, 211 African American controls. NA Affymetrix, Illumina [up to 10786384] (imputed) 8 longevity http://www.ebi.ac.uk/efo/EFO_0004300 GCST008600 Genome-wide genotyping array 41610 2019-09-05 31413261 Deelen J 2019-08-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31413261 A meta-analysis of genome-wide association studies identifies multiple longevity genes. Longevity (age >99th survival percentile) 3,484 European ancestry cases, 25,483 European ancestry controls 1,911 European ancestry cases, 4,987 European ancestry controls Illumina [up to 9449311] (imputed) 2 longevity http://www.ebi.ac.uk/efo/EFO_0004300 GCST008599 Genome-wide genotyping array 28967 2019-10-01 31417091 Kou I 2019-08-15 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31417091 Genome-wide association study identifies 14 previously unreported susceptibility loci for adolescent idiopathic scoliosis in Japanese. Adolescent idiopathic scoliosis 5,327 Japanese ancestry cases, 73,884 Japanese ancestry controls NA Illumina [9332516] (imputed) 26 adolescent idiopathic scoliosis http://www.ebi.ac.uk/efo/EFO_0005423 GCST008789 Genome-wide genotyping array 79211 2019-10-01 31417091 Kou I 2019-08-15 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31417091 Genome-wide association study identifies 14 previously unreported susceptibility loci for adolescent idiopathic scoliosis in Japanese. Adolescent idiopathic scoliosis 5,004 Japanese ancestry female cases, 33,679 Japanese ancestry female controls NA Illumina [9332516] (imputed) 15 adolescent idiopathic scoliosis http://www.ebi.ac.uk/efo/EFO_0005423 GCST008788 Genome-wide genotyping array 38683 2019-04-09 30478444 Demontis D 2018-11-26 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30478444 Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder. Attention deficit hyperactivity disorder 19,099 European ancestry cases, 72 non-European ancestry cases, 1,012 Han Chinese ancestry cases, 34,194 European ancestry controls, 72 non-European ancestry controls, 925 Han Chinese ancestry controls 5,085 Icelandic ancestry cases, 5,857 cases, 131,122 Icelandic ancestry controls, 70,393 controls Affymetrix, Illumina, Perlegen [8047421] (imputed) 15 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST007543 Genome-wide genotyping array 55374 2019-01-29 30498034 Terao C 2018-11-29 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/30498034 Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis. Takayasu arteritis 411 Japanese ancestry cases, 2,158 Japanese ancestry controls 219 Japanese ancestry cases, 3,770 Japanese ancestry controls Illumina [5878075] (imputed) 7 Takayasu arteritis http://www.ebi.ac.uk/efo/EFO_1001857 GCST006984 Genome-wide genotyping array 2569 2019-03-13 30480742 Miki A 2018-11-01 Invest Ophthalmol Vis Sci www.ncbi.nlm.nih.gov/pubmed/30480742 Genome-Wide Association Study to Identify a New Susceptibility Locus for Central Serous Chorioretinopathy in the Japanese Population. Chronic central serous retinopathy 137 Japanese ancestry cases, 1,174 Japanese ancestry controls 183 Japanese ancestry cases, 2,071 Japanese ancestry controls Illumina [548653] 2 chronic central serous retinopathy http://www.ebi.ac.uk/efo/EFO_0009363 GCST007296 Genome-wide genotyping array 1311 2019-04-29 30488612 Xiang B 2018-11-28 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/30488612 GWAS and network analysis of co-occurring nicotine and alcohol dependence identifies significantly associated alleles and network. Alcohol and nicotine co-dependence 1,079 European ancestry cases, 128 European ancestry controls, 1,303 African American cases, 791 African American controls 637 European ancestry cases, 41 European ancestry controls Illumina [37426733] (imputed) 0 alcohol and nicotine codependence http://www.ebi.ac.uk/efo/EFO_0004776 GCST007657 Genome-wide genotyping array 3301 2019-04-03 30410027 Gudmundsson J 2018-11-08 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30410027 Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA. Benign prostatic hyperplasia and lower urinary tract symptoms 20,621 European ancestry cases, 280,541 European ancestry controls NA Affymetrix, Illumina [42907111] (imputed) 23 lower urinary tract symptom, benign prostatic hyperplasia http://www.ebi.ac.uk/efo/EFO_0008008, http://www.ebi.ac.uk/efo/EFO_0000284 GCST007507 Genome-wide genotyping array 301162 2019-04-04 30410027 Gudmundsson J 2018-11-08 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30410027 Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA. Benign prostatic hyperplasia and lower urinary tract symptoms (prostate cancer excluded) 18,138 European ancestry cases, 277,213 European ancestry controls NA Affymetrix, Illumina [42907111] (imputed) 22 lower urinary tract symptom, benign prostatic hyperplasia http://www.ebi.ac.uk/efo/EFO_0008008, http://www.ebi.ac.uk/efo/EFO_0000284 GCST007512 Genome-wide genotyping array 295351 2019-04-03 30410027 Gudmundsson J 2018-11-08 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30410027 Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA. Prostate cancer 11,708 European ancestry cases, 284,184 European ancestry controls NA Affymetrix, Illumina [42907111] (imputed) 1 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST007506 Genome-wide genotyping array 295892 2019-04-04 30410027 Gudmundsson J 2018-11-08 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30410027 Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA. Prostate-specific antigen levels 33,572 Icelandic ancestry individuals NA Affymetrix, Illumina [up to 32463442] (imputed) 8 prostate specific antigen measurement http://www.ebi.ac.uk/efo/EFO_0004624 GCST007513 Genome-wide genotyping array 33572 2019-04-17 30392061 Orlova E 2018-11-03 Hum Genet www.ncbi.nlm.nih.gov/pubmed/30392061 Genetic association and differential expression of PITX2 with acute appendicitis. Appendicitis 18,773 European ancestry cases, 114,907 European ancestry controls 59 European ancestry cases, 607 European ancestry controls, 7,267 Icelandic ancestry cases, 327,134 Icelandic ancestry controls, 1,139 Dutch ancestry cases, 4,587 Dutch ancestry controls Illumina [NR] (imputed) 1 appendicitis http://www.ebi.ac.uk/efo/EFO_0007149 GCST007595 Genome-wide genotyping array 133680 2019-09-16 30449631 Zeng X 2018-11-15 Environ Int www.ncbi.nlm.nih.gov/pubmed/30449631 Genome-wide interaction study of gene-by-occupational exposures on respiratory symptoms. Cough x occupational exposure (biological dust, mineral dust, gases and fumes, pesticides, aromatic solvents, chlorinated solvents, other solvents or metals) interaction 675 Dutch ancestry cough cases, 7,301 Dutch ancestry controls 584 Dutch ancestry cough cases, 6,205 Dutch ancestry controls Illumina [227981] 0 respiratory symptom measurement, environmental exposure measurement http://www.ebi.ac.uk/efo/EFO_0007939, http://www.ebi.ac.uk/efo/EFO_0008360 GCST008669 Genome-wide genotyping array 7976 2019-09-16 30449631 Zeng X 2018-11-15 Environ Int www.ncbi.nlm.nih.gov/pubmed/30449631 Genome-wide interaction study of gene-by-occupational exposures on respiratory symptoms. Dyspnea x occupational exposure (biological dust, mineral dust, gases and fumes, pesticides, aromatic solvents, chlorinated solvents, other solvents or metals) interaction 547 Dutch ancestry dyspnea cases, 7,429 Dutch ancestry controls 505 Dutch ancestry dyspnea cases, 6,284 Dutch ancestry controls Illumina [227981] 0 respiratory symptom measurement, environmental exposure measurement http://www.ebi.ac.uk/efo/EFO_0007939, http://www.ebi.ac.uk/efo/EFO_0008360 GCST008670 Genome-wide genotyping array 7976 2019-09-16 30449631 Zeng X 2018-11-15 Environ Int www.ncbi.nlm.nih.gov/pubmed/30449631 Genome-wide interaction study of gene-by-occupational exposures on respiratory symptoms. Phlegm x occupational exposure (biological dust, mineral dust, gases and fumes, pesticides, aromatic solvents, chlorinated solvents, other solvents or metals) interaction 1,702 Dutch ancestry phlegm cases, 6,274 Dutch ancestry controls 1,405 Dutch ancestry phlegm cases, 5,384 Dutch ancestry controls Illumina [227981] 0 respiratory symptom measurement, environmental exposure measurement http://www.ebi.ac.uk/efo/EFO_0007939, http://www.ebi.ac.uk/efo/EFO_0008360 GCST008671 Genome-wide genotyping array 7976 2019-07-15 30252935 Smith AH 2018-09-25 Alcohol Clin Exp Res www.ncbi.nlm.nih.gov/pubmed/30252935 Risk locus identification ties alcohol withdrawal symptoms to SORCS2. Alcohol withdrawal symptoms 1,231 African American individuals NA Illumina [NR] (imputed) 0 alcohol withdrawal http://www.ebi.ac.uk/efo/EFO_0004777 GCST008136 Genome-wide genotyping array 1231 2019-07-15 30252935 Smith AH 2018-09-25 Alcohol Clin Exp Res www.ncbi.nlm.nih.gov/pubmed/30252935 Risk locus identification ties alcohol withdrawal symptoms to SORCS2. Alcohol withdrawal symptoms 1,297 European American individuals 181 European American individuals Illumina [NR] (imputed) 1 alcohol withdrawal http://www.ebi.ac.uk/efo/EFO_0004777 GCST008137 Genome-wide genotyping array 1297 2019-07-05 30230522 Zhang S 2018-09-19 Br J Dermatol www.ncbi.nlm.nih.gov/pubmed/30230522 Subtype-Specific Inherited Predisposition to Pemphigus in Chinese Population. Pemphigus foliaceus 72 Chinese ancestry cases, 501 Chinese ancestry controls 32 Chinese ancestry cases, 604 Chinese ancestry controls Affymetrix [416397] 0 pemphigus foliaceus http://www.ebi.ac.uk/efo/EFO_0008601 GCST008067 Genome-wide genotyping array 573 2019-07-05 30230522 Zhang S 2018-09-19 Br J Dermatol www.ncbi.nlm.nih.gov/pubmed/30230522 Subtype-Specific Inherited Predisposition to Pemphigus in Chinese Population. Pemphigus 350 Chinese ancestry cases, 501 Chinese ancestry controls 146 Chinese ancestry cases, 604 Chinese ancestry controls Affymetrix [416397] 2 pemphigus http://www.ebi.ac.uk/efo/EFO_1000749 GCST008069 Genome-wide genotyping array 851 2019-07-05 30230522 Zhang S 2018-09-19 Br J Dermatol www.ncbi.nlm.nih.gov/pubmed/30230522 Subtype-Specific Inherited Predisposition to Pemphigus in Chinese Population. Pemphigus vulgaris 255 Chinese ancestry cases, 501 Chinese ancestry controls 110 Chinese ancestry cases, 604 Chinese ancestry controls Affymetrix [416397] 2 pemphigus vulgaris http://www.ebi.ac.uk/efo/EFO_0004719 GCST008068 Genome-wide genotyping array 756 2019-07-24 31277774 Lipunova N 2018-09-15 Eur Urol Oncol www.ncbi.nlm.nih.gov/pubmed/31277774 Genome-wide Association Study for Tumour Stage, Grade, Size, and Age at Diagnosis of Non-muscle-invasive Bladder Cancer. Non-muscle-invasive bladder cancer age at diagnosis 653 European ancestry cases 1470 European ancestry cases Illumina [11914228] (imputed) 0 bladder carcinoma, age at diagnosis http://www.ebi.ac.uk/efo/EFO_0000292, http://www.ebi.ac.uk/efo/EFO_0004918 GCST008217 Genome-wide genotyping array 653 2019-07-24 31277774 Lipunova N 2018-09-15 Eur Urol Oncol www.ncbi.nlm.nih.gov/pubmed/31277774 Genome-wide Association Study for Tumour Stage, Grade, Size, and Age at Diagnosis of Non-muscle-invasive Bladder Cancer. Non-muscle-invasive bladder cancer age at diagnosis (< 70 years vs ≥ 70 years) 298 European ancestry cases under 70 years, 355 European ancestry cases 70 years or older 329 European ancestry cases under 70 years, 1,141 European ancestry cases 70 years or older Illumina [11914228] (imputed) 0 bladder carcinoma, age at diagnosis http://www.ebi.ac.uk/efo/EFO_0000292, http://www.ebi.ac.uk/efo/EFO_0004918 GCST008218 Genome-wide genotyping array 793 2019-07-24 31277774 Lipunova N 2018-09-15 Eur Urol Oncol www.ncbi.nlm.nih.gov/pubmed/31277774 Genome-wide Association Study for Tumour Stage, Grade, Size, and Age at Diagnosis of Non-muscle-invasive Bladder Cancer. Non-muscle-invasive bladder cancer tumour size 633 European ancestry cases 302 European ancestry cases Illumina [11914228] (imputed) 1 bladder carcinoma, disease progression measurement http://www.ebi.ac.uk/efo/EFO_0000292, http://www.ebi.ac.uk/efo/EFO_0008336 GCST008216 Genome-wide genotyping array 633 2019-07-24 31277774 Lipunova N 2018-09-15 Eur Urol Oncol www.ncbi.nlm.nih.gov/pubmed/31277774 Genome-wide Association Study for Tumour Stage, Grade, Size, and Age at Diagnosis of Non-muscle-invasive Bladder Cancer. Non-muscle-invasive bladder cancer tumour size (< 3 cm vs ≥ 3 cm) 633 European ancestry cases 302 European ancestry cases Illumina [11914228] (imputed) 0 bladder carcinoma, disease progression measurement http://www.ebi.ac.uk/efo/EFO_0000292, http://www.ebi.ac.uk/efo/EFO_0008336 GCST008219 Genome-wide genotyping array 633 2019-07-24 31277774 Lipunova N 2018-09-15 Eur Urol Oncol www.ncbi.nlm.nih.gov/pubmed/31277774 Genome-wide Association Study for Tumour Stage, Grade, Size, and Age at Diagnosis of Non-muscle-invasive Bladder Cancer. Non-muscle-invasive bladder cancer tumour stage (Tis/T1 vs Ta) 209 European ancestry stage Tis/T1 cases, 444 European ancestry stage Ta cases 414 European ancestry stage Tis/T1 cases, 1,056 European ancestry stage Ta cases Illumina [11914228] (imputed) 0 bladder carcinoma, disease progression measurement http://www.ebi.ac.uk/efo/EFO_0000292, http://www.ebi.ac.uk/efo/EFO_0008336 GCST008220 Genome-wide genotyping array 654 2019-07-24 31277774 Lipunova N 2018-09-15 Eur Urol Oncol www.ncbi.nlm.nih.gov/pubmed/31277774 Genome-wide Association Study for Tumour Stage, Grade, Size, and Age at Diagnosis of Non-muscle-invasive Bladder Cancer. Non-muscle-invasive bladder cancer tumour grade (G3 vs G2/G1) 207 European ancestry grade G3 cases, 436 European ancestry grade G2/G1 cases 304 European ancestry grade G3 cases, 1,019 European ancestry grade G2/G1 cases Illumina [11914228] (imputed) 0 bladder carcinoma, disease progression measurement http://www.ebi.ac.uk/efo/EFO_0000292, http://www.ebi.ac.uk/efo/EFO_0008336 GCST008221 Genome-wide genotyping array 649 2019-07-24 31277774 Lipunova N 2018-09-15 Eur Urol Oncol www.ncbi.nlm.nih.gov/pubmed/31277774 Genome-wide Association Study for Tumour Stage, Grade, Size, and Age at Diagnosis of Non-muscle-invasive Bladder Cancer. Non-muscle-invasive bladder cancer EORTC risk category 311 European ancestry high risk cases, 342 European ancestry low/intermediate risk cases NA Illumina [11914228] (imputed) 0 bladder carcinoma, disease prognosis measurement http://www.ebi.ac.uk/efo/EFO_0000292, http://www.ebi.ac.uk/efo/EFO_0007936 GCST008222 Genome-wide genotyping array 653 2019-08-19 31271701 Thibord F 2019-07-04 J Thromb Haemost www.ncbi.nlm.nih.gov/pubmed/31271701 A Genome Wide Association Study on plasma FV levels identified PLXDC2 as a new modifier of the coagulation process. Plasma factor V levels in venous thrombosis 510 European ancestry individuals 1,156 European ancestry individuals NR [6264382] (imputed) 2 coagulation factor V measurement http://www.ebi.ac.uk/efo/EFO_0008087 GCST008461 Genome-wide genotyping array 510 2019-08-19 31271701 Thibord F 2019-07-04 J Thromb Haemost www.ncbi.nlm.nih.gov/pubmed/31271701 A Genome Wide Association Study on plasma FV levels identified PLXDC2 as a new modifier of the coagulation process. Plasma factor V levels in venous thrombosis (conditioned on rs6027) 510 European ancestry individuals 1,156 European ancestry individuals NR [6264382] (imputed) 11 coagulation factor V measurement http://www.ebi.ac.uk/efo/EFO_0008087 GCST008462 Genome-wide genotyping array 510 2019-09-20 31407831 Din L 2019-08-13 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31407831 Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes. Chronic lymphocytic leukemia or multiple sclerosis 2,492 European ancestry chronic lymphocytic leukemia cases, 9,772 European ancestry multiple sclerosis cases, 24,529 European ancestry controls NA Illumina [~ 460000] (imputed) 7 multiple sclerosis, chronic lymphocytic leukemia http://www.ebi.ac.uk/efo/EFO_0003885, http://www.ebi.ac.uk/efo/EFO_0000095 GCST008721 Genome-wide genotyping array 36793 2019-09-20 31407831 Din L 2019-08-13 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31407831 Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes. Diffuse large B-cell lymphoma or multiple sclerosis 3,617 European ancestry diffuse large B-cell lymphoma cases, 9,772 European ancestry multiple sclerosis cases, 24,813 European ancestry controls NA Illumina [~ 460000] (imputed) 5 multiple sclerosis, diffuse large B-cell lymphoma http://www.ebi.ac.uk/efo/EFO_0003885, http://www.ebi.ac.uk/efo/EFO_0000403 GCST008722 Genome-wide genotyping array 38202 2019-09-20 31407831 Din L 2019-08-13 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31407831 Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes. Follicular lymphoma or multiple sclerosis 2,686 European ancestry follicular lymphoma cases, 9,772 European ancestry multiple sclerosis cases, 25,256 European ancestry controls NA Illumina [~ 460000] (imputed) 2 multiple sclerosis, follicular lymphoma http://www.ebi.ac.uk/efo/EFO_0003885, http://purl.obolibrary.org/obo/MONDO_0018906 GCST008718 Genome-wide genotyping array 37714 2019-09-20 31407831 Din L 2019-08-13 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31407831 Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes. Marginal zone lymphoma or multiple sclerosis 741 European ancestry marginal zone lymphoma cases, 9,772 European ancestry multiple sclerosis cases, 23,367 European ancestry controls NA Illumina [~ 460000] (imputed) 7 multiple sclerosis, marginal zone B-cell lymphoma http://www.ebi.ac.uk/efo/EFO_0003885, http://www.ebi.ac.uk/efo/EFO_1000630 GCST008723 Genome-wide genotyping array 33880 2019-09-20 31407831 Din L 2019-08-13 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31407831 Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes. Chronic lymphocytic leukemia or rheumatoid arthritis 2,492 European ancestry chronic lymphocytic leukemia cases, 3,921 European ancestry rheumatoid arthritis cases, 11,232 European ancestry controls NA Illumina [~ 600000] (imputed) 1 rheumatoid arthritis, chronic lymphocytic leukemia http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0000095 GCST008724 Genome-wide genotyping array 17645 2019-09-20 31407831 Din L 2019-08-13 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31407831 Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes. Diffuse large B-cell lymphoma or rheumatoid arthritis 3,617 European ancestry diffuse large B-cell lymphoma cases, 3,921 European ancestry rheumatoid arthritis cases, 11,516 European ancestry controls NA Illumina [~ 600000] (imputed) 1 diffuse large B-cell lymphoma, rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000403, http://www.ebi.ac.uk/efo/EFO_0000685 GCST008725 Genome-wide genotyping array 19054 2019-09-20 31407831 Din L 2019-08-13 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31407831 Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes. Follicular lymphoma or rheumatoid arthritis 2,686 European ancestry follicular lymphoma cases, 3,921 European ancestry rheumatoid arthritis cases, 11,959 European ancestry controls NA Illumina [~ 600000] (imputed) 1 rheumatoid arthritis, follicular lymphoma http://www.ebi.ac.uk/efo/EFO_0000685, http://purl.obolibrary.org/obo/MONDO_0018906 GCST008719 Genome-wide genotyping array 18566 2019-09-20 31407831 Din L 2019-08-13 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31407831 Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes. Marginal zone lymphoma or rheumatoid arthritis 741 European ancestry marginal zone lymphoma cases, 3,921 European ancestry rheumatoid arthritis cases, 10,070 European ancestry controls NA Illumina [~ 600000] (imputed) 2 rheumatoid arthritis, marginal zone B-cell lymphoma http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_1000630 GCST008726 Genome-wide genotyping array 14732 2019-09-20 31407831 Din L 2019-08-13 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31407831 Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes. Chronic lymphocytic leukemia or systemic lupus erythematosus 2,492 European ancestry chronic lymphocytic leukemia cases, 7,219 European ancestry systemic lupus erythematosus cases, 23,144 European ancestry controls NA Illumina [~ 600000] (imputed) 4 systemic lupus erythematosus, chronic lymphocytic leukemia http://www.ebi.ac.uk/efo/EFO_0002690, http://www.ebi.ac.uk/efo/EFO_0000095 GCST008727 Genome-wide genotyping array 32855 2019-09-20 31407831 Din L 2019-08-13 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31407831 Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes. Diffuse large B-cell lymphoma or systemic lupus erythematosus 3,617 European ancestry diffuse large B-cell lymphoma cases, 7,219 European ancestry systemic lupus erythematosus cases, 23,428 European ancestry controls NA Illumina [~ 600000] (imputed) 1 diffuse large B-cell lymphoma, systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0000403, http://www.ebi.ac.uk/efo/EFO_0002690 GCST008728 Genome-wide genotyping array 34264 2019-09-20 31407831 Din L 2019-08-13 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31407831 Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes. Follicular lymphoma or systemic lupus erythematosus 2,686 European ancestry follicular lymphoma cases, 7,219 European ancestry systemic lupus erythematosus cases, 23,871 European ancestry controls NA Illumina [~ 600000] (imputed) 0 follicular lymphoma, systemic lupus erythematosus http://purl.obolibrary.org/obo/MONDO_0018906, http://www.ebi.ac.uk/efo/EFO_0002690 GCST008720 Genome-wide genotyping array 33776 2019-09-20 31407831 Din L 2019-08-13 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31407831 Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes. Marginal zone lymphoma or systemic lupus erythematosus 741 European ancestry marginal zone lymphoma cases, 7,219 European ancestry systemic lupus erythematosus cases, 21,982 European ancestry controls NA Illumina [~ 600000] (imputed) 4 marginal zone B-cell lymphoma, systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_1000630, http://www.ebi.ac.uk/efo/EFO_0002690 GCST008729 Genome-wide genotyping array 29942 2019-08-28 30571770 Arnau-Soler A 2018-12-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/30571770 Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder. Stress sensitivity (neuroticism score x major depressive disorder status interaction) 2,010 European ancestry cases, 5,145 European ancestry controls NA NR [560698] (imputed) 10 unipolar depression, neuroticism measurement http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0007660 GCST008506 Genome-wide genotyping array 7155 2019-08-28 30571770 Arnau-Soler A 2018-12-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/30571770 Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder. Stress sensitivity (neuroticism score x major depressive disorder status interaction) 7,834 European ancestry cases, 15,258 European ancestry controls NA Affymetrix [557813] (imputed) 3 unipolar depression, neuroticism measurement http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0007660 GCST008507 Genome-wide genotyping array 23092 2019-08-28 30571770 Arnau-Soler A 2018-12-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/30571770 Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder. Stress sensitivity (neuroticism score x major depressive disorder status interaction) 9,844 European ancestry cases, 20,403 European ancestry controls NA Affymetrix [at least 557813] (imputed) 9 unipolar depression, neuroticism measurement http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0007660 GCST008508 Genome-wide genotyping array 30247 2019-08-28 30571770 Arnau-Soler A 2018-12-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/30571770 Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder. Major depressive disorder 9,844 European ancestry cases, 20,403 European ancestry controls NA Affymetrix [at least 557813] (imputed) 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST008509 Genome-wide genotyping array 30247 2019-08-28 30571770 Arnau-Soler A 2018-12-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/30571770 Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder. Neuroticism 30,247 European ancestry individuals NA Affymetrix [at least 557813] (imputed) 0 neuroticism measurement http://www.ebi.ac.uk/efo/EFO_0007660 GCST008510 Genome-wide genotyping array 30247 2019-01-15 30395268 Khanshour AM 2018-11-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30395268 Genome-wide meta-analysis and replication studies in multiple ethnicities identify novel adolescent idiopathic scoliosis susceptibility loci. Adolescent idiopathic scoliosis 2,295 East Asian ancestry cases, 11,084 East Asian ancestry controls, 1,503 European ancestry cases, 18,594 European ancestry controls 2,737 East Asian ancestry cases, 56,815 East Asian ancestry controls, 1,421 European ancestry cases, 1,966 European ancestry controls Affymetrix, Illumina [3493832] (imputed) 10 adolescent idiopathic scoliosis http://www.ebi.ac.uk/efo/EFO_0005423 GCST006902 Genome-wide genotyping array 33476 2019-01-21 29970889 Day FR 2018-07-03 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29970889 Elucidating the genetic basis of social interaction and isolation. Loneliness 80,134 European ancestry cases, 364,890 European ancestry controls NA NR [NR] (imputed) 15 loneliness measurement http://www.ebi.ac.uk/efo/EFO_0007865 GCST006923 Genome-wide genotyping array 445024 2019-01-21 29970889 Day FR 2018-07-03 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29970889 Elucidating the genetic basis of social interaction and isolation. Social isolation 2,426 European ancestry cases, 286,524 European ancestry controls NA NR [NR] (imputed) 0 social interaction measurement http://www.ebi.ac.uk/efo/EFO_0009592 GCST006918 Genome-wide genotyping array 288950 2019-01-21 29970889 Day FR 2018-07-03 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29970889 Elucidating the genetic basis of social interaction and isolation. Ability to confide in someone 64,505 European ancestry cases, 238,062 European ancestry controls NA NR [NR] (imputed) 4 social interaction measurement http://www.ebi.ac.uk/efo/EFO_0009592 GCST006919 Genome-wide genotyping array 302567 2019-01-21 29970889 Day FR 2018-07-03 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29970889 Elucidating the genetic basis of social interaction and isolation. Regular attendance at a gym or sports club 135,060 European ancestry cases, 317,242 European ancestry controls NA NR [NR] (imputed) 8 social interaction measurement http://www.ebi.ac.uk/efo/EFO_0009592 GCST006920 Genome-wide genotyping array 452302 2019-01-21 29970889 Day FR 2018-07-03 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29970889 Elucidating the genetic basis of social interaction and isolation. Regular attendance at a pub or social club 124,047 European ancestry cases, 328,255 European ancestry controls NA NR [NR] (imputed) 13 social interaction measurement http://www.ebi.ac.uk/efo/EFO_0009592 GCST006921 Genome-wide genotyping array 452302 2019-01-21 29970889 Day FR 2018-07-03 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29970889 Elucidating the genetic basis of social interaction and isolation. Regular attendance at a religious group 66,259 European ancestry cases, 386,043 European ancestry controls NA NR [NR] (imputed) 19 social interaction measurement http://www.ebi.ac.uk/efo/EFO_0009592 GCST006922 Genome-wide genotyping array 452302 2019-01-21 29970889 Day FR 2018-07-03 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29970889 Elucidating the genetic basis of social interaction and isolation. Loneliness (MTAG) 487,647 European ancestry individuals NA NR [NR] (imputed) 16 loneliness measurement http://www.ebi.ac.uk/efo/EFO_0007865 GCST006924 Genome-wide genotyping array 487647 2019-08-28 31263163 Liu CT 2019-07-01 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31263163 Genome-wide Association Study of Change in Fasting Glucose over time in 13,807 non-diabetic European Ancestry Individuals. Fasting glucose change 13,807 European ancestry individuals NA Affymetrix, Illumina [~ 25000000] (imputed) 3 fasting blood glucose change measurement http://www.ebi.ac.uk/efo/EFO_0010120 GCST008503 Genome-wide genotyping array 13807 2019-08-28 31263163 Liu CT 2019-07-01 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31263163 Genome-wide Association Study of Change in Fasting Glucose over time in 13,807 non-diabetic European Ancestry Individuals. Fasting glucose change (long-term) 3,669 European ancestry individuals NA Affymetrix, Illumina [~ 25000000] (imputed) 11 fasting blood glucose change measurement http://www.ebi.ac.uk/efo/EFO_0010120 GCST008504 Genome-wide genotyping array 3669 2019-08-28 31263163 Liu CT 2019-07-01 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31263163 Genome-wide Association Study of Change in Fasting Glucose over time in 13,807 non-diabetic European Ancestry Individuals. Fasting glucose change (short-term) 8,195 European ancestry individuals NA Affymetrix, Illumina [~ 25000000] (imputed) 4 fasting blood glucose change measurement http://www.ebi.ac.uk/efo/EFO_0010120 GCST008505 Genome-wide genotyping array 8195 2019-08-29 31260374 Pedergnana V 2019-07-01 J Interferon Cytokine Res www.ncbi.nlm.nih.gov/pubmed/31260374 Impact of IFNL4 Genetic Variants on Sustained Virologic Response and Viremia in Hepatitis C Virus Genotype 3 Patients. Response to interferon treatment in hepatitis C virus genotype 3 717 European, Asian and unknown ancestry responders, 541 European, Asian and unknown ancestry non-responders NA Affymetrix [~ 18000000] (imputed) 8 response to interferon http://www.ebi.ac.uk/efo/EFO_0007859 GCST008517 Genome-wide genotyping array 1258 2019-08-29 31260374 Pedergnana V 2019-07-01 J Interferon Cytokine Res www.ncbi.nlm.nih.gov/pubmed/31260374 Impact of IFNL4 Genetic Variants on Sustained Virologic Response and Viremia in Hepatitis C Virus Genotype 3 Patients. Response to direct-acting antiviral treatment in hepatitis C virus genotype 3 325 European, Asian and unknown ancestry responders, 84 European, Asian and unknown ancestry non-responders NA Affymetrix [~ 18000000] (imputed) 10 response to antiviral drug http://www.ebi.ac.uk/efo/EFO_0010123 GCST008520 Genome-wide genotyping array 409 2019-08-29 31260374 Pedergnana V 2019-07-01 J Interferon Cytokine Res www.ncbi.nlm.nih.gov/pubmed/31260374 Impact of IFNL4 Genetic Variants on Sustained Virologic Response and Viremia in Hepatitis C Virus Genotype 3 Patients. Pre-treatment viral load in hepatitis C virus genotype 3 1,498 European, Asian and unknown ancestry individuals NA Affymetrix [~ 18000000] (imputed) 1 viral load http://www.ebi.ac.uk/efo/EFO_0010125 GCST008515 Genome-wide genotyping array 1498 2019-08-16 31269844 Wu NN 2019-07-03 J Matern Fetal Neonatal Med www.ncbi.nlm.nih.gov/pubmed/31269844 A genome-wide association study of gestational diabetes mellitus in Chinese women. Diabetes (gestational) 103 Han Chinese ancestry cases, 115 Han Chinese ancestry controls NA Illumina [65535] 3 gestational diabetes http://www.ebi.ac.uk/efo/EFO_0004593 GCST008448 Genome-wide genotyping array 218 2019-08-19 31262040 Pujol-Moix N 2019-06-30 Int J Mol Sci www.ncbi.nlm.nih.gov/pubmed/31262040 Influence of ABO Locus on PFA-100 Collagen-ADP Closure Time Is Not Totally Dependent on the Von Willebrand Factor. Results of a GWAS on GAIT-2 Project Phenotypes. Platelet reactivity measurement (collagen-ADP) 935 Spanish ancestry individuals NA NR [10844567] (imputed) 1 platelet reactivity measurement http://www.ebi.ac.uk/efo/EFO_0004985 GCST008458 Genome-wide genotyping array 935 2019-08-19 31262040 Pujol-Moix N 2019-06-30 Int J Mol Sci www.ncbi.nlm.nih.gov/pubmed/31262040 Influence of ABO Locus on PFA-100 Collagen-ADP Closure Time Is Not Totally Dependent on the Von Willebrand Factor. Results of a GWAS on GAIT-2 Project Phenotypes. Platelet reactivity measurement (collagen-epinephrine) 935 Spanish ancestry individuals NA Illumina [10844567] (imputed) 1 platelet reactivity measurement http://www.ebi.ac.uk/efo/EFO_0004985 GCST008457 Genome-wide genotyping array 935 2020-01-20 31272903 Sunadome H 2019-07-01 Allergol Int www.ncbi.nlm.nih.gov/pubmed/31272903 Correlation between eosinophil count, its genetic background and body mass index: The Nagahama Study. Eosinophil counts 4,650 East Asian ancestry individuals NA Illumina [103680] (imputed) 9 eosinophil count http://www.ebi.ac.uk/efo/EFO_0004842 GCST009456 Genome-wide genotyping array 4650 2020-01-20 31272903 Sunadome H 2019-07-01 Allergol Int www.ncbi.nlm.nih.gov/pubmed/31272903 Correlation between eosinophil count, its genetic background and body mass index: The Nagahama Study. Eosinophil counts 4,206 East Asian ancestry individuals NA Illumina [103680] (imputed) 5 eosinophil count http://www.ebi.ac.uk/efo/EFO_0004842 GCST009457 Genome-wide genotyping array 4206 2019-05-02 30487518 Takeuchi F 2018-11-28 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30487518 Interethnic analyses of blood pressure loci in populations of East Asian and European descent. Systolic blood pressure 130,777 Japanese ancestry individuals 53,008 East Asian individuals, 105,253 European ancestry individuals Illumina [6200000] (imputed) 146 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST007703 Genome-wide genotyping array 130777 2019-05-02 30487518 Takeuchi F 2018-11-28 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30487518 Interethnic analyses of blood pressure loci in populations of East Asian and European descent. Diastolic blood pressure 130,777 Japanese ancestry individuals 53,008 East Asian individuals, 105,253 European ancestry individuals Illumina [6200000] (imputed) 122 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST007704 Genome-wide genotyping array 130777 2019-05-02 30487518 Takeuchi F 2018-11-28 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30487518 Interethnic analyses of blood pressure loci in populations of East Asian and European descent. Pulse pressure 130,777 Japanese ancestry individuals 53,008 East Asian individuals, 105,253 Japanese ancestry individuals Illumina [6200000] (imputed) 94 pulse pressure measurement http://www.ebi.ac.uk/efo/EFO_0005763 GCST007705 Genome-wide genotyping array 130777 2019-05-02 30487518 Takeuchi F 2018-11-28 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30487518 Interethnic analyses of blood pressure loci in populations of East Asian and European descent. Mean arterial pressure 130,777 Japanese ancestry individuals 53,008 East Asian individuals, 105,253 European ancestry individuals Illumina [6200000] (imputed) 149 mean arterial pressure http://www.ebi.ac.uk/efo/EFO_0006340 GCST007706 Genome-wide genotyping array 130777 2019-05-02 30487518 Takeuchi F 2018-11-28 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30487518 Interethnic analyses of blood pressure loci in populations of East Asian and European descent. Hypertension 22,566 Japanese ancestry cases, 28,226 Japanese ancestry controls 8,809 East Asian ancestry cases, 13,663 East Asian ancestry controls, 105,253 European ancestry individuals Illumina [6200000] (imputed) 106 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST007707 Genome-wide genotyping array 50792 2019-08-08 31178898 Lin BM 2019-05-24 Front Genet www.ncbi.nlm.nih.gov/pubmed/31178898 Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study. End-stage kidney disease 584 African American cases, 282 Hispanic cases, 112 East Asian cases, 96 Native Hawaiian cases, 1 American Indian cases, 30 cases, 8,429 African American controls, 15,852 Hispanic controls, 3,536 East Asian controls, 2,892 Native Hawaiian controls, 49 American Indian controls, 936 controls NA Illumina [1438399] (imputed) 15 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST008395 Genome-wide genotyping array 32799 2019-08-08 31178898 Lin BM 2019-05-24 Front Genet www.ncbi.nlm.nih.gov/pubmed/31178898 Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study. Mild to moderate chronic kidney disease 1,532 African American cases, 1,336 Hispanic cases, 575 East Asian cases, 608 Native Hawaiian cases, 42 American Indian cases, 57 cases, 13,761 African American controls, 19,317 Hispanic controls, 3,540 East Asian controls, 2,892 Native Hawaiian controls, 595 American Indian controls, 936 controls NA Illumina [1438399] (imputed) 12 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST008394 Genome-wide genotyping array 45191 2019-09-20 31413141 Deming Y 2019-08-01 Sci Transl Med www.ncbi.nlm.nih.gov/pubmed/31413141 The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk. Cerebrospinal fluid sTREM-2 levels 813 individuals 580 individuals Illumina [7320475] (imputed) 2 soluble triggering receptor expressed on myeloid cells 2 measurement http://www.ebi.ac.uk/efo/EFO_0010151 GCST008706 Genome-wide genotyping array 813 2019-09-20 31417607 Gazal S 2019-07-30 Front Genet www.ncbi.nlm.nih.gov/pubmed/31417607 The Genetic Architecture of Chronic Mountain Sickness in Peru. Chronic mountain sickness 166 Quechua cases, 146 Quechua controls NA Affymetrix [1288199] 4 chronic mountain sickness http://www.ebi.ac.uk/efo/EFO_0010143 GCST008708 Genome-wide genotyping array 312 2019-09-12 31409800 Pazoki R 2019-08-13 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31409800 GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits. Urinary sodium excretion 446,237 European ancestry individuals 7,612 African ancestry individuals, 10,095 South Asian ancestry individuals Affymetrix [~ 8800000] (imputed) 50 sodium measurement http://www.ebi.ac.uk/efo/EFO_0009282 GCST008647 Genome-wide genotyping array 446237 2019-09-12 31409800 Pazoki R 2019-08-13 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31409800 GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits. Urinary potassium excretion 446,230 European ancestry individuals 7,612 African ancestry individuals, 10,095 South Asian ancestry individuals Affymetrix [~ 8800000] (imputed) 13 potassium measurement http://www.ebi.ac.uk/efo/EFO_0009283 GCST008648 Genome-wide genotyping array 446230 2019-01-21 29907492 Nakahara S 2018-06-12 Schizophr Res www.ncbi.nlm.nih.gov/pubmed/29907492 Polygenic risk score, genome-wide association, and gene set analyses of cognitive domain deficits in schizophrenia. Attention function 2 Alaskan native ancestry schizophrenia cases, 18 Asian ancestry schizophrenia cases, 20 African American schizophrenia cases, 1 Native Hawaiian ancestry schizophrenia cases, 86 European ancestry schizophrenia cases, 2 Alaskan native ancestry controls, 10 Asian ancestry controls, 17 African American controls, 1 Native Hawaiian ancestry controls, 106 European ancestry controls NA Illumina [NR] (imputed) 1 attention function measurement http://www.ebi.ac.uk/efo/EFO_0007636 GCST006929 Genome-wide genotyping array 263 2019-01-21 29907492 Nakahara S 2018-06-12 Schizophr Res www.ncbi.nlm.nih.gov/pubmed/29907492 Polygenic risk score, genome-wide association, and gene set analyses of cognitive domain deficits in schizophrenia. Working memory 2 Alaskan native ancestry schizophrenia cases, 18 Asian ancestry schizophrenia cases, 20 African American schizophrenia cases, 1 Native Hawaiian ancestry schizophrenia cases, 86 European ancestry schizophrenia cases, 2 Alaskan native ancestry controls, 10 Asian ancestry controls, 17 African American controls, 1 Native Hawaiian ancestry controls, 106 European ancestry controls NA Illumina [NR] (imputed) 3 short-term memory http://www.ebi.ac.uk/efo/EFO_0004335 GCST006930 Genome-wide genotyping array 263 2019-01-21 29907492 Nakahara S 2018-06-12 Schizophr Res www.ncbi.nlm.nih.gov/pubmed/29907492 Polygenic risk score, genome-wide association, and gene set analyses of cognitive domain deficits in schizophrenia. Verbal memory 2 Alaskan native ancestry schizophrenia cases, 18 Asian ancestry schizophrenia cases, 20 African American schizophrenia cases, 1 Native Hawaiian ancestry schizophrenia cases, 86 European ancestry schizophrenia cases, 2 Alaskan native ancestry controls, 10 Asian ancestry controls, 17 African American controls, 1 Native Hawaiian ancestry controls, 106 European ancestry controls NA Illumina [NR] (imputed) 3 verbal memory measurement http://www.ebi.ac.uk/efo/EFO_0009591 GCST006931 Genome-wide genotyping array 263 2019-01-21 29907492 Nakahara S 2018-06-12 Schizophr Res www.ncbi.nlm.nih.gov/pubmed/29907492 Polygenic risk score, genome-wide association, and gene set analyses of cognitive domain deficits in schizophrenia. Visual memory 2 Alaskan native ancestry schizophrenia cases, 18 Asian ancestry schizophrenia cases, 20 African American schizophrenia cases, 1 Native Hawaiian ancestry schizophrenia cases, 86 European ancestry schizophrenia cases, 2 Alaskan native ancestry controls, 10 Asian ancestry controls, 17 African American controls, 1 Native Hawaiian ancestry controls, 106 European ancestry controls NA Illumina [NR] (imputed) 2 visual memory measurement http://www.ebi.ac.uk/efo/EFO_0009590 GCST006928 Genome-wide genotyping array 263 2019-01-21 29907492 Nakahara S 2018-06-12 Schizophr Res www.ncbi.nlm.nih.gov/pubmed/29907492 Polygenic risk score, genome-wide association, and gene set analyses of cognitive domain deficits in schizophrenia. Reasoning 2 Alaskan native ancestry schizophrenia cases, 18 Asian ancestry schizophrenia cases, 20 African American schizophrenia cases, 1 Native Hawaiian ancestry schizophrenia cases, 86 European ancestry schizophrenia cases, 2 Alaskan native ancestry controls, 10 Asian ancestry controls, 17 African American controls, 1 Native Hawaiian ancestry controls, 106 European ancestry controls NA Illumina [NR] (imputed) 3 reasoning http://www.ebi.ac.uk/efo/EFO_0004350 GCST006932 Genome-wide genotyping array 263 2019-01-21 29907492 Nakahara S 2018-06-12 Schizophr Res www.ncbi.nlm.nih.gov/pubmed/29907492 Polygenic risk score, genome-wide association, and gene set analyses of cognitive domain deficits in schizophrenia. Cognitive function 2 Alaskan native ancestry schizophrenia cases, 18 Asian ancestry schizophrenia cases, 20 African American schizophrenia cases, 1 Native Hawaiian ancestry schizophrenia cases, 86 European ancestry schizophrenia cases, 2 Alaskan native ancestry controls, 10 Asian ancestry controls, 17 African American controls, 1 Native Hawaiian ancestry controls, 106 European ancestry controls NA Illumina [NR] (imputed) 3 cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0008354 GCST006933 Genome-wide genotyping array 263 2019-01-21 29907492 Nakahara S 2018-06-12 Schizophr Res www.ncbi.nlm.nih.gov/pubmed/29907492 Polygenic risk score, genome-wide association, and gene set analyses of cognitive domain deficits in schizophrenia. Information processing speed 2 Alaskan native ancestry schizophrenia cases, 18 Asian ancestry schizophrenia cases, 20 African American schizophrenia cases, 1 Native Hawaiian ancestry schizophrenia cases, 86 European ancestry schizophrenia cases, 2 Alaskan native ancestry controls, 10 Asian ancestry controls, 17 African American controls, 1 Native Hawaiian ancestry controls, 106 European ancestry controls NA Illumina [NR] (imputed) 1 information processing speed http://www.ebi.ac.uk/efo/EFO_0004363 GCST006934 Genome-wide genotyping array 263 2019-02-28 27736895 Franceschini N 2016-10-13 PLoS One www.ncbi.nlm.nih.gov/pubmed/27736895 Variant Discovery and Fine Mapping of Genetic Loci Associated with Blood Pressure Traits in Hispanics and African Americans. Diastolic blood pressure 19,706 Hispanic individuals, 18,744 African American individuals NA Illumina [up to 196725] 5 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST007238 Targeted genotyping array [MetaboChip] 38450 2019-02-28 27736895 Franceschini N 2016-10-13 PLoS One www.ncbi.nlm.nih.gov/pubmed/27736895 Variant Discovery and Fine Mapping of Genetic Loci Associated with Blood Pressure Traits in Hispanics and African Americans. Systolic blood pressure 19,706 Hispanic individuals, 18,744 African American individuals NA Illumina [up to 196725] 3 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST007237 Targeted genotyping array [MetaboChip] 38450 2018-08-29 29912962 Feitosa MF 2018-06-18 PLoS One www.ncbi.nlm.nih.gov/pubmed/29912962 Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) 12,758 European ancestry heavy drinkers, 1,326 African American or Afro-Caribbean heavy drinkers, 648 Asian ancestry heavy drinkers, 364 Hispanic or Latin American heavy drinkers, 43,947 European ancestry light drinkers, 8,239 African American or Afro-Caribbean light drinkers, 1,141 Asian ancestry light drinkers, 4,448 Hispanic or Latin American light drinkers 42,079 European ancestry heavy drinkers, 217 African American or Afro-Caribbean heavy drinkers, 282,294 Asian ancestry heavy drinkers, 124 Hispanic ancestry heavy drinkers, 74,757 European ancestry light drinkers, 845 African American light drinkers, 24,129 Asian ancestry light drinkers, 411 Hispanic light drinkers Affymetrix, Illumina [up to 39321347] (imputed) 41 diastolic blood pressure, alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0007878 GCST006169 Genome-wide genotyping array 72871 2018-10-18 29912962 Feitosa MF 2018-06-18 PLoS One www.ncbi.nlm.nih.gov/pubmed/29912962 Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. Systolic blood pressure x alcohol consumption interaction (2df test) 63,608 European ancestry drinkers, 10,193 African American or Afro-Caribbean heavy drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,494 European ancestry non-drinkers, 11,224 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers 238,002 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,452 Hispanic drinkers, 43,316 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,945 Asian ancestry non-drinkers, 6,925 Hispanic non-drinkers Affymetrix, Illumina [up to 39321347] (imputed) 114 systolic blood pressure, alcohol drinking http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004329 GCST006434 Genome-wide genotyping array 133355 2018-08-29 29912962 Feitosa MF 2018-06-18 PLoS One www.ncbi.nlm.nih.gov/pubmed/29912962 Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) 12,758 European ancestry heavy drinkers, 1,326 African American or Afro-Caribbean heavy drinkers, 648 Asian ancestry heavy drinkers, 364 Hispanic or Latin American heavy drinkers, 43,947 European ancestry light drinkers, 8,239 African American or Afro-Caribbean light drinkers, 1,141 Asian ancestry light drinkers, 4,448 Hispanic or Latin American light drinkers 42,078 European ancestry heavy drinkers, 217 African American heavy drinkers, 282,294 Asian ancestry heavy drinkers, 124 Hispanic heavy drinkers, 74,706 European ancestry light drinkers, 845 African American light drinkers, 24,129 Asian ancestry light drinkers, 411 Hispanic light drinkers Affymetrix, Illumina [up to 39321347] (imputed) 43 systolic blood pressure, alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0007878 GCST006170 Genome-wide genotyping array 72871 2018-08-29 29912962 Feitosa MF 2018-06-18 PLoS One www.ncbi.nlm.nih.gov/pubmed/29912962 Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. Pulse pressure x alcohol consumption interaction (2df test) 91,099 European ancestry drinkers and non-drinkers, 21,416 African American or Afro-Caribbean drinkers and non-drinkers, 12,365 Asian ancestry drinkers and non-drinkers, 8,470 Hispanic or Latin American drinkers and non-drinkers 238,053 European ancestry drinkers, 2,280 African American drinkers, 54,080 Asian ancestry drinkers, 6,447 Hispanic ancestry drinkers, 43,318 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic ancestry non-drinkers Affymetrix, Illumina [up to 39321347] (imputed) 59 pulse pressure measurement, alcohol drinking http://www.ebi.ac.uk/efo/EFO_0005763, http://www.ebi.ac.uk/efo/EFO_0004329 GCST006168 Genome-wide genotyping array 133350 2018-08-29 29912962 Feitosa MF 2018-06-18 PLoS One www.ncbi.nlm.nih.gov/pubmed/29912962 Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) 56,705 European ancestry heavy and light drinkers, 9,725 African American or Afro-Caribbean heavy and light drinkers, 1,789 Asian ancestry heavy and light drinkers, 4,812 Hispanic or Latin American heavy and light drinkers 42,079 European ancestry heavy drinkers, 217 African American heavy drinkers, 282,294 Asian ancestry heavy drinkers, 124 Hispanic heavy drinkers, 74,756 European ancestry light drinkers, 845 African American light drinkers, 24,129 Asian ancestry light drinkers, 411 Hispanic light drinkers Affymetrix, Illumina [up to 39321347] (imputed) 17 pulse pressure measurement, alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0005763, http://www.ebi.ac.uk/efo/EFO_0007878 GCST006171 Genome-wide genotyping array 73031 2018-08-29 29912962 Feitosa MF 2018-06-18 PLoS One www.ncbi.nlm.nih.gov/pubmed/29912962 Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. Mean arterial pressure x alcohol consumption interaction (2df test) 91,110 European ancestry drinkers and non-drinkers, 21,416 African American or Afro-Caribbean drinkers and non-drinkers, 12,365 Asian ancestry drinkers and non-drinkers, 8,470 Hispanic or Latin American drinkers and non-drinkers 237,996 European ancestry drinkers, 2,280 African American drinkers, 54,080 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,315 European ancestry non-drinkers, 2,761 African ancestry non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers Affymetrix, Illumina [up to 39321347] (imputed) 85 mean arterial pressure, alcohol drinking http://www.ebi.ac.uk/efo/EFO_0006340, http://www.ebi.ac.uk/efo/EFO_0004329 GCST006167 Genome-wide genotyping array 133361 2018-08-29 29912962 Feitosa MF 2018-06-18 PLoS One www.ncbi.nlm.nih.gov/pubmed/29912962 Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) 56,705 European ancestry heavy and light drinkers, 9,725 African American or Afro-Caribbean heavy and light drinkers, 1,789 Asian ancestry heavy and light drinkers, 4,812 Hispanic or Latin American heavy and light drinkers 42,077 European ancestry heavy drinkers, 217 African American heavy drinkers, 282,294 Asian ancestry heavy drinkers, 124 Hispanic ancestry heavy drinkers, 74,701 European ancestry light drinkers, 845 African American light drinkers, 24,129 Asian ancestry light drinkers, 411 Hispanic light drinkers Affymetrix, Illumina [up to 39321347] (imputed) 41 mean arterial pressure, alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0006340, http://www.ebi.ac.uk/efo/EFO_0007878 GCST006172 Genome-wide genotyping array 73031 2018-08-29 29912962 Feitosa MF 2018-06-18 PLoS One www.ncbi.nlm.nih.gov/pubmed/29912962 Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. Diastolic blood pressure x alcohol consumption interaction (2df test) 63,607 European ancestry drinkers, 10,193 African American or Afro-Caribbean drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,492 European ancestry non-drinkers, 11,223 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers 238,058 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,448 Hispanic drinkers, 43,318 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,943 Asian ancestry non-drinkers, 6,923 Hispanic non-drinkers Affymetrix, Illumina [up to 39321347] (imputed) 114 diastolic blood pressure, alcohol drinking http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004329 GCST006166 Genome-wide genotyping array 133351 2019-10-30 30397551 Dorani F 2018-10-29 PeerJ www.ncbi.nlm.nih.gov/pubmed/30397551 Ensemble learning for detecting gene-gene interactions in colorectal cancer. Colorectal cancer 472 cases, 472 controls NA Affymetrix [186251] (imputed) 0 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST008977 Genome-wide genotyping array 944 2019-07-16 29981864 Mohammadnejad A 2018-07-05 Ann Allergy Asthma Immunol www.ncbi.nlm.nih.gov/pubmed/29981864 A case-only genome-wide association study on gene-sex interaction in allergic rhinitis. Allergic rhinitis x sex interaction 184 Danish ancestry male cases, 250 Danish ancestry female cases NA Affymetrix [1348667] (imputed) 1 sex interaction measurement, allergic rhinitis http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0005854 GCST008138 Genome-wide genotyping array 434 2019-08-01 31000673 Kim W 2019-04-18 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/31000673 A Genome-Wide Association Study implicates NR2F2 in Lymphangioleiomyomatosis Pathogenesis. Lymphangioleiomyomatosis (sporadic) 426 European ancestry cases, 852 European ancestry controls 196 European ancestry cases, up to 226,140 European ancestry controls, up to 1,121 Hispanic white controls Illumina [5426936] (imputed) 1 Lymphangioleiomyomatosis http://www.orpha.net/ORDO/Orphanet_538 GCST008311 Genome-wide genotyping array 1278 2019-09-02 31263887 Adams MJ 2019-07-01 Int J Epidemiol www.ncbi.nlm.nih.gov/pubmed/31263887 Factors associated with sharing e-mail information and mental health survey participation in large population cohorts. Mental health study participation (provided email address) 224,321 British ancestry cases, 147,096 British ancestry controls NA NR [16367095] (imputed) 16 health study participation http://www.ebi.ac.uk/efo/EFO_0010130 GCST008549 Genome-wide genotyping array 371417 2019-09-02 31263887 Adams MJ 2019-07-01 Int J Epidemiol www.ncbi.nlm.nih.gov/pubmed/31263887 Factors associated with sharing e-mail information and mental health survey participation in large population cohorts. Mental health study participation (completed survey) 122,647 British ancestry cases, 248,781 British ancestry controls NA NR [16367095] (imputed) 40 health study participation http://www.ebi.ac.uk/efo/EFO_0010130 GCST008550 Genome-wide genotyping array 371428 2019-08-16 31270906 Lai D 2019-07-03 Addict Biol www.ncbi.nlm.nih.gov/pubmed/31270906 Genome-wide association studies of the self-rating of effects of ethanol (SRE). Number of alcoholic drinks required to feel an effect (first five times drinking) 4,723 European ancestry individuals from 956 families, 1,527 African American individuals from 309 families 306 European ancestry individuals, 169 African American individuals Illumina [up to 15464468] (imputed) 1 response to alcohol http://www.ebi.ac.uk/efo/EFO_0005526 GCST008446 Genome-wide genotyping array 7515 2019-08-16 31270906 Lai D 2019-07-03 Addict Biol www.ncbi.nlm.nih.gov/pubmed/31270906 Genome-wide association studies of the self-rating of effects of ethanol (SRE). Number of alcoholic drinks required to feel an effect (long-term average) 4,723 European ancestry individuals from 956 families, 1,527 African American individuals from 309 families 306 European ancestry individuals, 169 African American individuals Illumina [up to 15464468] (imputed) 2 response to alcohol http://www.ebi.ac.uk/efo/EFO_0005526 GCST008447 Genome-wide genotyping array 7515 2019-08-19 31263063 Dufek S 2019-07-01 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/31263063 Genetic Identification of Two Novel Loci Associated with Steroid-Sensitive Nephrotic Syndrome. Childhood steroid-sensitive nephrotic syndrome 422 European ancestry cases, 5,642 European ancestry controls NA Illumina [5216266] (imputed) 19 nephrotic syndrome http://www.ebi.ac.uk/efo/EFO_0004255 GCST008456 Genome-wide genotyping array 6064 2019-08-22 26635082 Soler Artigas M 2015-12-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26635082 Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation. Lung function (FVC) 38,199 European ancestry adults 54,550 European ancestry adults, 5,062 children Affymetrix, Illumina [8694268] (imputed) 10 vital capacity http://www.ebi.ac.uk/efo/EFO_0004312 GCST008482 Genome-wide genotyping array 38199 2019-08-22 26635082 Soler Artigas M 2015-12-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26635082 Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation. Lung function (FEV1/FVC) 38,199 European ancestry adults 54,550 European ancestry adults, 5,062 children Affymetrix, Illumina [8694268] (imputed) 11 FEV/FEC ratio http://www.ebi.ac.uk/efo/EFO_0004713 GCST008481 Genome-wide genotyping array 38199 2019-08-22 26635082 Soler Artigas M 2015-12-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26635082 Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation. Lung function (FEV1) 38,199 European ancestry adults 54,550 European ancestry adults, 5,062 children Affymetrix, Illumina [8694268] (imputed) 13 forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0004314 GCST008480 Genome-wide genotyping array 38199 2020-01-17 31484785 Wright KM 2019-09-04 G3 (Bethesda) www.ncbi.nlm.nih.gov/pubmed/31484785 A Prospective Analysis of Genetic Variants Associated with Human Lifespan. Parental longevity (father's age at death or father's attained age) up to 699,000 European ancestry individuals NA Illumina [458865] 48 parental longevity http://www.ebi.ac.uk/efo/EFO_0007796 GCST009450 Genome-wide genotyping array 699000 2020-01-17 31484785 Wright KM 2019-09-04 G3 (Bethesda) www.ncbi.nlm.nih.gov/pubmed/31484785 A Prospective Analysis of Genetic Variants Associated with Human Lifespan. Parental longevity (mother's age at death or mother's attained age) up to 699,000 individuals NA Illumina [458525] 41 parental longevity http://www.ebi.ac.uk/efo/EFO_0007796 GCST009449 Genome-wide genotyping array 699000 2020-01-17 31484785 Wright KM 2019-09-04 G3 (Bethesda) www.ncbi.nlm.nih.gov/pubmed/31484785 A Prospective Analysis of Genetic Variants Associated with Human Lifespan. Parental longevity (mother's age at death) 270,548 European ancestry individuals NA Illumina [541493] 17 parental longevity http://www.ebi.ac.uk/efo/EFO_0007796 GCST009446 Genome-wide genotyping array 270548 2020-01-17 31484785 Wright KM 2019-09-04 G3 (Bethesda) www.ncbi.nlm.nih.gov/pubmed/31484785 A Prospective Analysis of Genetic Variants Associated with Human Lifespan. Parental longevity (father's age at death) 309,383 European ancestry individuals NA Illumina [541614] 27 parental longevity http://www.ebi.ac.uk/efo/EFO_0007796 GCST009447 Genome-wide genotyping array 309383 2020-01-17 31484785 Wright KM 2019-09-04 G3 (Bethesda) www.ncbi.nlm.nih.gov/pubmed/31484785 A Prospective Analysis of Genetic Variants Associated with Human Lifespan. Longevity up to 482,000 European ancestry individuals NA Illumina [~ 540852] 87 longevity http://www.ebi.ac.uk/efo/EFO_0004300 GCST009448 Genome-wide genotyping array 482000 2020-01-13 31597446 Veluchamy A 2019-10-10 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/31597446 Novel Genetic Locus Influencing Retinal Venular Tortuosity Is Also Associated With Risk of Coronary Artery Disease. Retinal arteriolar tortuosity 3,094 European ancestry individuals 1,413 European ancestry individuals Affymetrix, Illumina [NR] (imputed) 1 retinal vasculature measurement http://www.ebi.ac.uk/efo/EFO_0010554 GCST009420 Genome-wide genotyping array 3094 2020-01-13 31597446 Veluchamy A 2019-10-10 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/31597446 Novel Genetic Locus Influencing Retinal Venular Tortuosity Is Also Associated With Risk of Coronary Artery Disease. Maximum retinal arteriolar tortuosity 3,094 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 2 retinal vasculature measurement http://www.ebi.ac.uk/efo/EFO_0010554 GCST009421 Genome-wide genotyping array 3094 2020-01-13 31597446 Veluchamy A 2019-10-10 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/31597446 Novel Genetic Locus Influencing Retinal Venular Tortuosity Is Also Associated With Risk of Coronary Artery Disease. Retinal venular tortuosity 3,094 European ancestry individuals 1,413 European ancestry individuals Affymetrix, Illumina [NR] (imputed) 2 retinal vasculature measurement http://www.ebi.ac.uk/efo/EFO_0010554 GCST009422 Genome-wide genotyping array 3094 2020-01-13 31597446 Veluchamy A 2019-10-10 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/31597446 Novel Genetic Locus Influencing Retinal Venular Tortuosity Is Also Associated With Risk of Coronary Artery Disease. Maximum retinal venular tortuosity 3,094 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 1 retinal vasculature measurement http://www.ebi.ac.uk/efo/EFO_0010554 GCST009423 Genome-wide genotyping array 3094 2020-01-13 31597446 Veluchamy A 2019-10-10 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/31597446 Novel Genetic Locus Influencing Retinal Venular Tortuosity Is Also Associated With Risk of Coronary Artery Disease. Central retinal arteriolar equivalent 3,094 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 1 retinal vasculature measurement http://www.ebi.ac.uk/efo/EFO_0010554 GCST009424 Genome-wide genotyping array 3094 2020-01-13 31597446 Veluchamy A 2019-10-10 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/31597446 Novel Genetic Locus Influencing Retinal Venular Tortuosity Is Also Associated With Risk of Coronary Artery Disease. Central retinal vein equivalent 3,094 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 1 retinal vasculature measurement http://www.ebi.ac.uk/efo/EFO_0010554 GCST009425 Genome-wide genotyping array 3094 2020-01-13 31597446 Veluchamy A 2019-10-10 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/31597446 Novel Genetic Locus Influencing Retinal Venular Tortuosity Is Also Associated With Risk of Coronary Artery Disease. Retinal arteriole-to-venule ratio 3,094 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 1 retinal vasculature measurement http://www.ebi.ac.uk/efo/EFO_0010554 GCST009426 Genome-wide genotyping array 3094 2020-01-13 31597446 Veluchamy A 2019-10-10 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/31597446 Novel Genetic Locus Influencing Retinal Venular Tortuosity Is Also Associated With Risk of Coronary Artery Disease. Optic disc radius 3,094 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 2 optic disc measurement http://www.ebi.ac.uk/efo/EFO_0006936 GCST009427 Genome-wide genotyping array 3094 2019-11-04 31600170 Teumer A 2019-10-10 JCI Insight www.ncbi.nlm.nih.gov/pubmed/31600170 KCND3 potassium channel gene variant confers susceptibility to electrocardiographic early repolarization pattern. Early cardiac repolarization 3,305 European ancestry cases, 36,151 European ancestry controls NA Affymetrix, Illumina [up to 6976246] (imputed) 7 early cardiac repolarization measurement http://www.ebi.ac.uk/efo/EFO_0004885 GCST008991 Genome-wide genotyping array 39456 2020-01-09 31591132 Wu W 2019-10-07 Genetics www.ncbi.nlm.nih.gov/pubmed/31591132 Retrospective Association Analysis of Longitudinal Binary Traits Identifies Important Loci and Pathways in Cocaine Use. Longitudinal cocaine use 1,682 mostly never users, 296 moderate decrease users, 86 elevated chronic users, 167 mostly frequent users NA Illumina [10215072] (imputed) 12 cocaine use measurement http://www.ebi.ac.uk/efo/EFO_0010553 GCST009384 Genome-wide genotyping array 2231 2019-09-22 30098192 Shaaban S 2018-08-01 Invest Ophthalmol Vis Sci www.ncbi.nlm.nih.gov/pubmed/30098192 Genome-Wide Association Study Identifies a Susceptibility Locus for Comitant Esotropia and Suggests a Parent-of-Origin Effect. Esotropia 224 European ancestry accommodative cases, 826 European ancestry non-accommodative cases, 3,740 European ancestry controls 66 European ancestry accommodative cases, 689 European ancestry non-accommodative cases, 1,712 European ancestry controls Illumina [6470615] (imputed) 1 Esotropia http://purl.obolibrary.org/obo/HP_0000565 GCST008737 Genome-wide genotyping array 4790 2019-09-22 30098192 Shaaban S 2018-08-01 Invest Ophthalmol Vis Sci www.ncbi.nlm.nih.gov/pubmed/30098192 Genome-Wide Association Study Identifies a Susceptibility Locus for Comitant Esotropia and Suggests a Parent-of-Origin Effect. Accommodative esotropia 224 European ancestry cases, 749 European ancestry controls 66 European ancestry cases, 264 European ancestry controls Illumina [6470615] (imputed) 3 Accommodative esotropia http://purl.obolibrary.org/obo/HP_0020046 GCST008738 Genome-wide genotyping array 973 2019-09-22 30098192 Shaaban S 2018-08-01 Invest Ophthalmol Vis Sci www.ncbi.nlm.nih.gov/pubmed/30098192 Genome-Wide Association Study Identifies a Susceptibility Locus for Comitant Esotropia and Suggests a Parent-of-Origin Effect. Amblyopia 386 European ancestry cases, 1,700 European ancestry controls 45 European ancestry cases, 180 European ancestry controls Illumina [6470615] (imputed) 15 amblyopia http://purl.obolibrary.org/obo/MONDO_0001020 GCST008739 Genome-wide genotyping array 2086 2019-09-22 30098192 Shaaban S 2018-08-01 Invest Ophthalmol Vis Sci www.ncbi.nlm.nih.gov/pubmed/30098192 Genome-Wide Association Study Identifies a Susceptibility Locus for Comitant Esotropia and Suggests a Parent-of-Origin Effect. Hyperopia 361 European ancestry cases, 1,700 European ancestry controls 172 European ancestry cases, 690 European ancestry controls Illumina [6470615] (imputed) 4 hyperopia http://purl.obolibrary.org/obo/MONDO_0004891 GCST008740 Genome-wide genotyping array 2061 2019-09-22 30098192 Shaaban S 2018-08-01 Invest Ophthalmol Vis Sci www.ncbi.nlm.nih.gov/pubmed/30098192 Genome-Wide Association Study Identifies a Susceptibility Locus for Comitant Esotropia and Suggests a Parent-of-Origin Effect. Non-accommodative esotropia 826 European ancestry cases, 2,991 European ancestry controls 689 European ancestry cases, 1,448 European ancestry controls Illumina [6470615] (imputed) 4 Non-accomodative esotropia http://purl.obolibrary.org/obo/HP_0031760 GCST008741 Genome-wide genotyping array 3817 2019-10-28 31044621 Rimpela JM 2019-05-02 Blood Press www.ncbi.nlm.nih.gov/pubmed/31044621 Genome-wide association study of white-coat effect in hypertensive patients. White coat effect (clinic systolic blood pressure minus ambulatory systolic blood pressure) 206 Finnish ancestry individuals NA Illumina [629414] 4 response to stress, systolic blood pressure change measurement http://purl.obolibrary.org/obo/GO_0006950, http://www.ebi.ac.uk/efo/EFO_0006944 GCST008968 Genome-wide genotyping array 206 2019-10-28 31044621 Rimpela JM 2019-05-02 Blood Press www.ncbi.nlm.nih.gov/pubmed/31044621 Genome-wide association study of white-coat effect in hypertensive patients. White coat effect (clinic diastolic blood pressure minus ambulatory diastolic blood pressure) 206 Finnish ancestry individuals NA Illumina [629414] 6 diastolic blood pressure change measurement, response to stress http://www.ebi.ac.uk/efo/EFO_0006945, http://purl.obolibrary.org/obo/GO_0006950 GCST008969 Genome-wide genotyping array 206 2019-12-11 31522824 Liu Y 2019-09-06 J Dermatol Sci www.ncbi.nlm.nih.gov/pubmed/31522824 Genome-wide scan identified genetic variants associated with skin aging in a Chinese female population. Skin aging measurement 1,534 Han Chinese ancestry women 964 European ancestry women Illumina [6328611] (imputed) 5 skin aging measurement http://www.ebi.ac.uk/efo/EFO_0008006 GCST009252 Genome-wide genotyping array 1534 2019-12-11 31522824 Liu Y 2019-09-06 J Dermatol Sci www.ncbi.nlm.nih.gov/pubmed/31522824 Genome-wide scan identified genetic variants associated with skin aging in a Chinese female population. Skin aging measurement 1,084 Han Chinese ancestry women (>50 years old) 964 European ancestry women Illumina [6328611] (imputed) 4 skin aging measurement http://www.ebi.ac.uk/efo/EFO_0008006 GCST009251 Genome-wide genotyping array 1134 2019-12-16 31537649 Salem RM 2019-09-19 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/31537649 Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen. Diabetic nephropathy in type 1 diabetes 4,948 European ancestry cases, 12,076 European ancestry controls NA Illumina [up to 49000000] (imputed) 2 diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0000401 GCST009278 Genome-wide genotyping array 17024 2019-12-16 31537649 Salem RM 2019-09-19 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/31537649 Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen. Macroalbuminuria in type 1 diabetes 2,751 European ancestry cases, 12,124 European ancestry controls NA Illumina [up to 49000000] (imputed) 2 albuminuria http://www.ebi.ac.uk/efo/EFO_0004285 GCST009284 Genome-wide genotyping array 14875 2019-12-16 31537649 Salem RM 2019-09-19 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/31537649 Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen. End-stage renal disease in Type 1 diabetics 2,187 European ancestry cases, 12,101 European ancestry controls NA Illumina [up to 49000000] (imputed) 1 diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0000401 GCST009279 Genome-wide genotyping array 14288 2019-12-16 31537649 Salem RM 2019-09-19 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/31537649 Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen. Kidney disease (end stage renal disease vs non-end stage renal disease) in type 1 diabetes 2,187 European ancestry cases, 17,219 European ancestry controls NA Illumina [up to 49000000] (imputed) 1 diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0000401 GCST009280 Genome-wide genotyping array 19406 2019-12-16 31537649 Salem RM 2019-09-19 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/31537649 Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen. Kidney disease (end stage renal disease vs macroalbuminuria) in type 1 diabetes 2,187 European ancestry cases, 2,725 European ancestry controls NA Illumina [up to 49000000] (imputed) 1 albuminuria, diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0004285, http://www.ebi.ac.uk/efo/EFO_0000401 GCST009285 Genome-wide genotyping array 4912 2019-12-16 31537649 Salem RM 2019-09-19 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/31537649 Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen. Microalbuminuria in type 1 diabetes 2,447 European ancestry cases, 12,113 European ancestry controls NA Illumina [up to 49000000] (imputed) 7 Moderate albuminuria http://purl.obolibrary.org/obo/HP_0012594 GCST009281 Genome-wide genotyping array 14560 2019-12-16 31537649 Salem RM 2019-09-19 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/31537649 Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen. Chronic kidney disease (reduced eGFR or end stage renal disease) in type 1 diabetes 4,266 European ancestry cases, 14,838 European ancestry controls NA Illumina [up to 49000000] (imputed) 2 diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0000401 GCST009286 Genome-wide genotyping array 19104 2019-12-16 31537649 Salem RM 2019-09-19 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/31537649 Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen. Chronic kidney disease (end stage renal disease vs. normal eGFR) in type 1 diabetes 2,235 European ancestry cases, 14,993 European ancestry controls NA Illumina [up to 49000000] (imputed) 1 diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0000401 GCST009287 Genome-wide genotyping array 17228 2019-12-16 31537649 Salem RM 2019-09-19 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/31537649 Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen. Kidney disease (reduced eGFR and albuminuria or end stage renal disease) in type 1 diabetes 2,987 European ancestry cases, 11,766 European ancestry controls NA Illumina [up to 49000000] (imputed) 1 diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0000401 GCST009289 Genome-wide genotyping array 14753 2019-12-16 31537649 Salem RM 2019-09-19 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/31537649 Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen. Kidney disease (end stage renal disease or albuminuria) in type 1 diabetes 7,247 European ancestry cases, 12,053 European ancestry controls NA Illumina [up to 49000000] (imputed) 1 albuminuria, diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0004285, http://www.ebi.ac.uk/efo/EFO_0000401 GCST009292 Genome-wide genotyping array 19300 2020-01-27 31667592 Milet J 2019-10-30 Hum Genet www.ncbi.nlm.nih.gov/pubmed/31667592 First genome-wide association study of non-severe malaria in two birth cohorts in Benin. Recurrence of malaria infection (mild or asymptomatic) 525 Beninese individuals 250 Beninese individuals Illumina [15566900] (imputed) 2 disease recurrence, malaria http://www.ebi.ac.uk/efo/EFO_0004952, http://www.ebi.ac.uk/efo/EFO_0001068 GCST009515 Genome-wide genotyping array 525 2020-01-27 31667592 Milet J 2019-10-30 Hum Genet www.ncbi.nlm.nih.gov/pubmed/31667592 First genome-wide association study of non-severe malaria in two birth cohorts in Benin. Recurrence of mild malaria attacks 525 Beninese individuals 250 Beninese individuals Illumina [15566900] (imputed) 6 disease recurrence, malaria http://www.ebi.ac.uk/efo/EFO_0004952, http://www.ebi.ac.uk/efo/EFO_0001068 GCST009514 Genome-wide genotyping array 525 2019-09-22 30575882 Lotta LA 2018-12-01 JAMA www.ncbi.nlm.nih.gov/pubmed/30575882 Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors. Waist-to-hip ratio adjusted for BMI 660,648 European ancestry individuals NA Affymetrix [2446094] (imputed) 202 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST008733 Genome-wide genotyping array 660648 2019-09-22 30575882 Lotta LA 2018-12-01 JAMA www.ncbi.nlm.nih.gov/pubmed/30575882 Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors. Waist-hip ratio 663,598 European ancestry individuals NA Affymetrix [2446094] (imputed) 202 waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0004343 GCST008734 Genome-wide genotyping array 663598 2019-12-12 31537151 Freitag-Wolf S 2019-09-19 J Dent Res www.ncbi.nlm.nih.gov/pubmed/31537151 Smoking Modifies the Genetic Risk for Early-Onset Periodontitis. Early onset periodontitis x smoking status interaction 499 European ancestry ever-smoker cases, 242 European ancestry never-smoker cases NA NR [79780573] (imputed) 3 smoking status measurement, aggressive periodontitis http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0006342 GCST009253 Genome-wide genotyping array 741 2019-11-26 31545351 Irvin MR 2019-09-23 Am J Hypertens www.ncbi.nlm.nih.gov/pubmed/31545351 Genome wide association study of apparent treatment resistant hypertension in the CHARGE consortium: The CHARGE Pharmacogenetics Working Group. Resistant hypertension 931 European ancestry cases, 228 African American ancestry cases, 14,210 European ancestry controls, 2,480 African American ancestry controls NA Affymetrix, Illumina [NR] (imputed) 3 treatment-resistant hypertension http://www.ebi.ac.uk/efo/EFO_1002006 GCST009098 Genome-wide genotyping array 17849 2019-11-26 31545351 Irvin MR 2019-09-23 Am J Hypertens www.ncbi.nlm.nih.gov/pubmed/31545351 Genome wide association study of apparent treatment resistant hypertension in the CHARGE consortium: The CHARGE Pharmacogenetics Working Group. Resistance to antihypertensive treatment in hypertension 931 European ancestry cases, 228 African American ancestry cases, 5,266 European ancestry controls, 1,817 African American ancestry controls NA Affymetrix, Illumina [NR] (imputed) 4 treatment-resistant hypertension http://www.ebi.ac.uk/efo/EFO_1002006 GCST009103 Genome-wide genotyping array 8242 2019-11-26 31545351 Irvin MR 2019-09-23 Am J Hypertens www.ncbi.nlm.nih.gov/pubmed/31545351 Genome wide association study of apparent treatment resistant hypertension in the CHARGE consortium: The CHARGE Pharmacogenetics Working Group. Resistant hypertension 931 European ancestry cases, 14,210 European ancestry controls NA Affymetrix, Illumina [NR] (imputed) 2 treatment-resistant hypertension http://www.ebi.ac.uk/efo/EFO_1002006 GCST009102 Genome-wide genotyping array 15141 2019-11-26 31545351 Irvin MR 2019-09-23 Am J Hypertens www.ncbi.nlm.nih.gov/pubmed/31545351 Genome wide association study of apparent treatment resistant hypertension in the CHARGE consortium: The CHARGE Pharmacogenetics Working Group. Resistance to antihypertensive treatment in hypertension 931 European ancestry cases, 14,210 European ancestry controls 11,762 European ancestry cases, 42,850 European ancestry controls Affymetrix, Illumina [NR] (imputed) 1 treatment-resistant hypertension http://www.ebi.ac.uk/efo/EFO_1002006 GCST009101 Genome-wide genotyping array 15141 2019-11-26 31545351 Irvin MR 2019-09-23 Am J Hypertens www.ncbi.nlm.nih.gov/pubmed/31545351 Genome wide association study of apparent treatment resistant hypertension in the CHARGE consortium: The CHARGE Pharmacogenetics Working Group. Resistant hypertension 228 African American ancestry cases, 2,480 African American ancestry controls NA Affymetrix, Illumina [NR] (imputed) 4 treatment-resistant hypertension http://www.ebi.ac.uk/efo/EFO_1002006 GCST009100 Genome-wide genotyping array 2708 2019-11-26 31545351 Irvin MR 2019-09-23 Am J Hypertens www.ncbi.nlm.nih.gov/pubmed/31545351 Genome wide association study of apparent treatment resistant hypertension in the CHARGE consortium: The CHARGE Pharmacogenetics Working Group. Resistance to antihypertensive treatment in hypertension 228 African American ancestry cases, 2,480 African American ancestry controls 5,071 African American ancestry cases, 11,081 African American ancestry controls Affymetrix, Illumina [NR] (imputed) 0 treatment-resistant hypertension http://www.ebi.ac.uk/efo/EFO_1002006 GCST009099 Genome-wide genotyping array 2708 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Basal metabolic rate 341,584 European ancestry individuals NA NR [5554549] (imputed) 5 base metabolic rate measurement http://www.ebi.ac.uk/efo/EFO_0007777 GCST009129 Genome-wide genotyping array 341584 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Caudal anterior-cingulate cortex volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 11 caudal anterior cingulate cortex volume measurement http://www.ebi.ac.uk/efo/EFO_0010289 GCST009175 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Caudal middle frontal gyrus volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 12 caudal middle frontal gyrus volume measurement http://www.ebi.ac.uk/efo/EFO_0010290 GCST009178 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Cuneus cortex volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 19 cuneus cortex volume measurement http://www.ebi.ac.uk/efo/EFO_0010301 GCST009181 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Entorhinal cortical volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 7 entorhinal cortical volume http://www.ebi.ac.uk/efo/EFO_0005092 GCST009177 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Fusiform gyrus volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 7 fusiform gyrus volume measurement http://www.ebi.ac.uk/efo/EFO_0010305 GCST009176 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Inferior parietal cortex volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 11 inferior parietal cortex volume measurement http://www.ebi.ac.uk/efo/EFO_0010307 GCST009184 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Inferior temporal gyrus volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 7 inferior temporal gyrus volume measurement http://www.ebi.ac.uk/efo/EFO_0010308 GCST009185 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Isthmus-cingulate cortex volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 18 isthmus cingulate cortex volume measurement http://www.ebi.ac.uk/efo/EFO_0010310 GCST009212 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Lateral occipital cortex volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 11 lateral occipital cortex volume measurement http://www.ebi.ac.uk/efo/EFO_0010311 GCST009187 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Lateral orbital frontal cortex volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 14 lateral orbital frontal cortex volume measurement http://www.ebi.ac.uk/efo/EFO_0010312 GCST009189 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Lingual gyrus volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 14 lingual gyrus volume measurement http://www.ebi.ac.uk/efo/EFO_0010314 GCST009188 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Medial orbital frontal cortex volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 19 medial orbital frontal cortex volume measurement http://www.ebi.ac.uk/efo/EFO_0010315 GCST009190 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Middle temporal gyrus volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 7 middle temporal gyrus volume measurement http://www.ebi.ac.uk/efo/EFO_0010316 GCST009210 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Parahippocampal gyrus volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 11 parahippocampal gyrus volume measurement http://www.ebi.ac.uk/efo/EFO_0010318 GCST009192 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Paracentral lobule volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 13 paracentral lobule volume measurement http://www.ebi.ac.uk/efo/EFO_0010317 GCST009191 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Pars opercularis volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 17 pars opercularis volume measurement http://www.ebi.ac.uk/efo/EFO_0010319 GCST009193 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Pars orbitalis volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 8 pars orbitalis volume measurement http://www.ebi.ac.uk/efo/EFO_0010320 GCST009180 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Pars triangularis volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 14 pars triangularis volume measurement http://www.ebi.ac.uk/efo/EFO_0010321 GCST009179 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Pericalcarine cortex volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 10 pericalcarine cortex volume measurement http://www.ebi.ac.uk/efo/EFO_0010322 GCST009196 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Postcentral gyrus volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 7 postcentral gyrus volume measurement http://www.ebi.ac.uk/efo/EFO_0010323 GCST009215 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Posterior-cingulate cortex volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 12 posterior cingulate cortex volume measurement http://www.ebi.ac.uk/efo/EFO_0010324 GCST009183 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Precentral gyrus volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 7 precentral gyrus volume measurement http://www.ebi.ac.uk/efo/EFO_0010325 GCST009199 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Precuneus cortex volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 12 precuneus cortex volume measurement http://www.ebi.ac.uk/efo/EFO_0010326 GCST009182 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Rostral anterior cingulate cortex volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 10 rostral anterior cingulate cortex volume measurement http://www.ebi.ac.uk/efo/EFO_0010327 GCST009221 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Rostral middle frontal gyrus volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 9 rostral middle frontal gyrus volume measurement http://www.ebi.ac.uk/efo/EFO_0010328 GCST009202 Genome-wide genotyping array 777 2019-10-16 31326317 Dai J 2019-07-17 Lancet Respir Med www.ncbi.nlm.nih.gov/pubmed/31326317 Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations. Squamous cell lung carcinoma 3,860 Chinese ancestry cases, 4,490 European ancestry cases, 13,328 Chinese ancestry controls, 14,027 European ancestry controls NA Illumina [~ 11000000] (imputed) 3 squamous cell lung carcinoma http://www.ebi.ac.uk/efo/EFO_0000708 GCST008835 Genome-wide genotyping array 35705 2019-10-16 31326317 Dai J 2019-07-17 Lancet Respir Med www.ncbi.nlm.nih.gov/pubmed/31326317 Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations. Lung adenocarcinoma 8,762 Chinese ancestry cases, 6,819 European ancestry cases, 13,328 Chinese ancestry controls, 14,027 European ancestry controls NA Illumina [~ 11000000] (imputed) 19 lung adenocarcinoma http://www.ebi.ac.uk/efo/EFO_0000571 GCST008836 Genome-wide genotyping array 42936 2019-10-16 31326317 Dai J 2019-07-17 Lancet Respir Med www.ncbi.nlm.nih.gov/pubmed/31326317 Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations. Non-small cell lung cancer 13,327 Chinese ancestry cases, 13,793 European ancestry cases, 13,328 Chinese ancestry controls, 14,027 European ancestry controls NA Illumina [~ 11000000] (imputed) 28 non-small cell lung carcinoma http://www.ebi.ac.uk/efo/EFO_0003060 GCST008834 Genome-wide genotyping array 54475 2019-11-29 31388106 Sofer T 2019-08-06 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31388106 Variants Associated with the Ankle Brachial Index Differ by Hispanic/Latino Ethnic Group: a genome-wide association study in the Hispanic Community Health Study/Study of Latinos. Ankle-brachial index 760 Central American ancestry individuals up to 8,527 European ancestry individuals, 2,362 African American individuals, 1,447 Hispanic/Latino individuals Illumina [27887661] (imputed) 1 ankle brachial index http://www.ebi.ac.uk/efo/EFO_0003912 GCST009139 Genome-wide genotyping array 760 2019-11-29 31388106 Sofer T 2019-08-06 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31388106 Variants Associated with the Ankle Brachial Index Differ by Hispanic/Latino Ethnic Group: a genome-wide association study in the Hispanic Community Health Study/Study of Latinos. Ankle-brachial index 1,500 Cuban ancestry individuals NA Illumina [27887661] (imputed) 1 ankle brachial index http://www.ebi.ac.uk/efo/EFO_0003912 GCST009137 Genome-wide genotyping array 1500 2019-11-29 31388106 Sofer T 2019-08-06 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31388106 Variants Associated with the Ankle Brachial Index Differ by Hispanic/Latino Ethnic Group: a genome-wide association study in the Hispanic Community Health Study/Study of Latinos. Ankle-brachial index 2,619 Mexican ancestry individuals NA Illumina [27887661] (imputed) 0 ankle brachial index http://www.ebi.ac.uk/efo/EFO_0003912 GCST009138 Genome-wide genotyping array 2619 2019-11-29 31388106 Sofer T 2019-08-06 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31388106 Variants Associated with the Ankle Brachial Index Differ by Hispanic/Latino Ethnic Group: a genome-wide association study in the Hispanic Community Health Study/Study of Latinos. Ankle-brachial index 700 Dominican ancestry individuals up to 8,527 European ancestry individuals, 2,362 African American individuals, 1,447 Hispanic/Latino individuals Illumina [27887661] (imputed) 1 ankle brachial index http://www.ebi.ac.uk/efo/EFO_0003912 GCST009135 Genome-wide genotyping array 700 2019-11-29 31388106 Sofer T 2019-08-06 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31388106 Variants Associated with the Ankle Brachial Index Differ by Hispanic/Latino Ethnic Group: a genome-wide association study in the Hispanic Community Health Study/Study of Latinos. Ankle-brachial index 553 South American ancestry individuals NA Illumina [27887661] (imputed) 0 ankle brachial index http://www.ebi.ac.uk/efo/EFO_0003912 GCST009140 Genome-wide genotyping array 553 2019-11-29 31388106 Sofer T 2019-08-06 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31388106 Variants Associated with the Ankle Brachial Index Differ by Hispanic/Latino Ethnic Group: a genome-wide association study in the Hispanic Community Health Study/Study of Latinos. Ankle-brachial index 1,437 Puerto Rican ancestry individuals up to 8,527 European ancestry individuals, 2,362 African American individuals, 1,447 Hispanic/Latino individuals Illumina [27887661] (imputed) 2 ankle brachial index http://www.ebi.ac.uk/efo/EFO_0003912 GCST009136 Genome-wide genotyping array 1437 2019-11-29 31388106 Sofer T 2019-08-06 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31388106 Variants Associated with the Ankle Brachial Index Differ by Hispanic/Latino Ethnic Group: a genome-wide association study in the Hispanic Community Health Study/Study of Latinos. Ankle-brachial index 3,637 Caribbean ancestry individuals up to 8,527 European ancestry individuals, 2,362 African American individuals, 1,447 Hispanic/Latino individuals Illumina [27887661] (imputed) 1 ankle brachial index http://www.ebi.ac.uk/efo/EFO_0003912 GCST009141 Genome-wide genotyping array 3637 2019-11-29 31388106 Sofer T 2019-08-06 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31388106 Variants Associated with the Ankle Brachial Index Differ by Hispanic/Latino Ethnic Group: a genome-wide association study in the Hispanic Community Health Study/Study of Latinos. Peripheral artery disease 382 Hispanic/Latino cases, 7,015 Hispanic/Latino controls NA Illumina [27887661] (imputed) 0 peripheral arterial disease http://www.ebi.ac.uk/efo/EFO_0004265 GCST009133 Genome-wide genotyping array 7397 2019-11-29 31388106 Sofer T 2019-08-06 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31388106 Variants Associated with the Ankle Brachial Index Differ by Hispanic/Latino Ethnic Group: a genome-wide association study in the Hispanic Community Health Study/Study of Latinos. Peripheral artery disease (borderline) 2,104 Hispanic/Latino cases, 5,293 Hispanic/Latino controls NA Illumina [27887661] (imputed) 1 peripheral arterial disease http://www.ebi.ac.uk/efo/EFO_0004265 GCST009134 Genome-wide genotyping array 7397 2019-11-29 31388106 Sofer T 2019-08-06 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31388106 Variants Associated with the Ankle Brachial Index Differ by Hispanic/Latino Ethnic Group: a genome-wide association study in the Hispanic Community Health Study/Study of Latinos. Ankle-brachial index 7,589 Hispanic/Latino individuals NA Illumina [27887661] (imputed) 0 ankle brachial index http://www.ebi.ac.uk/efo/EFO_0003912 GCST009132 Genome-wide genotyping array 7589 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Superior frontal gyrus volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 9 superior frontal gyrus volume measurement http://www.ebi.ac.uk/efo/EFO_0010329 GCST009219 Genome-wide genotyping array 777 2019-12-13 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Superior parietal cortex volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 12 superior parietal cortex volume measurement http://www.ebi.ac.uk/efo/EFO_0010330 GCST009265 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Superior temporal gyrus volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 13 superior temporal gyrus volume measurement http://www.ebi.ac.uk/efo/EFO_0010331 GCST009213 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Supramarginal gyrus volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 15 supramarginal gyrus volume measurement http://www.ebi.ac.uk/efo/EFO_0010332 GCST009205 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Frontal pole volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 12 frontal pole volume measurement http://www.ebi.ac.uk/efo/EFO_0010304 GCST009209 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Temporal pole volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 8 temporal pole volume measurement http://www.ebi.ac.uk/efo/EFO_0010334 GCST009195 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Transverse temporal cortex volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 9 transverse temporal cortex volume measurement http://www.ebi.ac.uk/efo/EFO_0010336 GCST009208 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Insular cortex volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 15 insular cortex volume measurement http://www.ebi.ac.uk/efo/EFO_0010309 GCST009186 Genome-wide genotyping array 777 2019-12-13 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Thalamus volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 17 thalamus volume http://www.ebi.ac.uk/efo/EFO_0006935 GCST009264 Genome-wide genotyping array 777 2019-12-13 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Caudate nucleus volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 11 caudate nucleus volume http://www.ebi.ac.uk/efo/EFO_0004830 GCST009257 Genome-wide genotyping array 777 2019-12-13 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Putamen volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 7 putamen volume http://www.ebi.ac.uk/efo/EFO_0006932 GCST009262 Genome-wide genotyping array 777 2019-12-13 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Pallidum volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 12 pallidum volume http://www.ebi.ac.uk/efo/EFO_0006933 GCST009261 Genome-wide genotyping array 777 2019-12-13 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Hippocampal volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 12 hippocampal volume http://www.ebi.ac.uk/efo/EFO_0005035 GCST009260 Genome-wide genotyping array 777 2019-12-13 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Amygdala volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 10 amygdala volume http://www.ebi.ac.uk/efo/EFO_0006934 GCST009259 Genome-wide genotyping array 777 2019-12-13 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Nucleus accumbens volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 8 nucleus accumbens volume http://www.ebi.ac.uk/efo/EFO_0006931 GCST009258 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Ventral diencephalon volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 4 ventral diencephalon volume measurement http://www.ebi.ac.uk/efo/EFO_0010337 GCST009194 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Choroid plexus volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 7 choroid plexus volume measurement http://www.ebi.ac.uk/efo/EFO_0010293 GCST009211 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Lateral ventricle volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 18 lateral ventricle volume measurement http://www.ebi.ac.uk/efo/EFO_0008487 GCST009207 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Lateral ventricle temporal horn volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 49 temporal horn of lateral ventricle volume measurement http://www.ebi.ac.uk/efo/EFO_0010333 GCST009218 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Third ventricle volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 11 third ventricle volume measurement http://www.ebi.ac.uk/efo/EFO_0010335 GCST009214 Genome-wide genotyping array 777 2019-12-13 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Fourth ventricle volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 15 fourth ventricle volume measurement http://www.ebi.ac.uk/efo/EFO_0010303 GCST009255 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Corpus callosum posterior volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 6 corpus callosum posterior volume measurement http://www.ebi.ac.uk/efo/EFO_0010298 GCST009222 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Corpus callosum Mid-posterior volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 7 corpus collosum mid-posterior volume measurement http://www.ebi.ac.uk/efo/EFO_0010300 GCST009217 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Corpus callosum central volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 10 corpus callosum central volume measurement http://www.ebi.ac.uk/efo/EFO_0010296 GCST009216 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Corpus callosum mid-anterior volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 5 corpus callosum mid-anterior volume measurement http://www.ebi.ac.uk/efo/EFO_0010297 GCST009198 Genome-wide genotyping array 777 2019-12-13 31533690 Orlova E 2019-09-18 BMC Oral Health www.ncbi.nlm.nih.gov/pubmed/31533690 Pilot GWAS of caries in African-Americans shows genetic heterogeneity. Dental caries (decayed, missing and filled tooth surfaces) 109 African American adults NA Illumina [~ 4900000] (imputed) 11 dental caries http://www.ebi.ac.uk/efo/EFO_0003819 GCST009268 Genome-wide genotyping array 109 2019-12-13 31533690 Orlova E 2019-09-18 BMC Oral Health www.ncbi.nlm.nih.gov/pubmed/31533690 Pilot GWAS of caries in African-Americans shows genetic heterogeneity. Dental caries (decayed, missing and filled teeth) 109 African American adults NA Illumina [~ 4900000] (imputed) 25 dental caries http://www.ebi.ac.uk/efo/EFO_0003819 GCST009267 Genome-wide genotyping array 109 2019-12-13 31533690 Orlova E 2019-09-18 BMC Oral Health www.ncbi.nlm.nih.gov/pubmed/31533690 Pilot GWAS of caries in African-Americans shows genetic heterogeneity. Dental caries (decayed and filled deciduous teeth) 96 African American children NA Illumina [~ 4900000] (imputed) 25 dental caries http://www.ebi.ac.uk/efo/EFO_0003819 GCST009269 Genome-wide genotyping array 96 2019-12-13 31533690 Orlova E 2019-09-18 BMC Oral Health www.ncbi.nlm.nih.gov/pubmed/31533690 Pilot GWAS of caries in African-Americans shows genetic heterogeneity. Dental caries (decayed and filled deciduous tooth surfaces) 96 African American children NA Illumina [~ 4900000] (imputed) 17 dental caries http://www.ebi.ac.uk/efo/EFO_0003819 GCST009266 Genome-wide genotyping array 96 2019-11-04 31615970 Rodas G 2019-10-14 Int J Sports Physiol Perform www.ncbi.nlm.nih.gov/pubmed/31615970 Genomic Prediction of Tendinopathy Risk in Elite Team Sports. Tendinopathy 181 European ancestry cases, 12 African American cases, 5 Brazilian cases, 1 Asian ancestry cases, 147 European ancestry controls, 9 African American controls, 7 Brazilian controls, 2 Asian ancestry controls NA Illumina [1419369] (imputed) 2 Tendinopathy http://www.ebi.ac.uk/efo/EFO_1001434 GCST009002 Genome-wide genotyping array 364 2019-12-19 31606302 Schijven D 2019-10-09 Eur Neuropsychopharmacol www.ncbi.nlm.nih.gov/pubmed/31606302 Multivariate genome-wide analysis of stress-related quantitative phenotypes. Stress-related phenotypes (multivariate analysis) 583 European and other ancestry individuals NA Illumina [5361288] (imputed) 2 response to stress http://purl.obolibrary.org/obo/GO_0006950 GCST009326 Genome-wide genotyping array 583 2019-10-15 31118516 Flannick J 2019-05-22 Nature www.ncbi.nlm.nih.gov/pubmed/31118516 Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. Type 2 diabetes 2,277 African American cases, 3,098 East Asian ancestry cases, 3,704 European ancestry cases, 6,215 Hispanic/Latino cases, 2,939 South Asian ancestry cases, 2,283 African American controls, 2,921 East Asian ancestry controls, 3,514 European ancestry controls, 5,939 Hispanic/Latino controls, 3,022 South Asian ancestry controls NA Affymetrix, Illumina [up to 35256845] (imputed) 25 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST008833 Genome-wide genotyping array 35912 2019-10-25 31586183 Niazi Y 2019-10-04 Mutagenesis www.ncbi.nlm.nih.gov/pubmed/31586183 Distinct pathways associated with chromosomal aberration frequency in a cohort exposed to genotoxic compounds compared to general population. Chromosomal aberration frequency (total) 866 European and unknown ancestry individuals NA Illumina [> 2600000] (imputed) 3 chromosomal aberration frequency http://www.ebi.ac.uk/efo/EFO_0009860 GCST008940 Genome-wide genotyping array 866 2019-10-25 31586183 Niazi Y 2019-10-04 Mutagenesis www.ncbi.nlm.nih.gov/pubmed/31586183 Distinct pathways associated with chromosomal aberration frequency in a cohort exposed to genotoxic compounds compared to general population. High chromosomal aberration frequency (chromatid type) 333 European and unknown ancestry cases, 533 European and unknown ancestry controls NA Illumina [> 2600000] (imputed) 2 chromatid-type aberration frequency http://www.ebi.ac.uk/efo/EFO_0009862 GCST008941 Genome-wide genotyping array 866 2019-10-25 31586183 Niazi Y 2019-10-04 Mutagenesis www.ncbi.nlm.nih.gov/pubmed/31586183 Distinct pathways associated with chromosomal aberration frequency in a cohort exposed to genotoxic compounds compared to general population. Chromosomal aberration frequency (chromatid type) 866 European and unknown ancestry individuals NA Illumina [> 2600000] (imputed) 4 chromatid-type aberration frequency http://www.ebi.ac.uk/efo/EFO_0009862 GCST008942 Genome-wide genotyping array 866 2019-10-25 31586183 Niazi Y 2019-10-04 Mutagenesis www.ncbi.nlm.nih.gov/pubmed/31586183 Distinct pathways associated with chromosomal aberration frequency in a cohort exposed to genotoxic compounds compared to general population. High chromosomal aberration frequency (chromosome type) 333 European and unknown ancestry cases, 533 European and unknown ancestry controls NA Illumina [> 2600000] (imputed) 2 chromosome-type aberration frequency http://www.ebi.ac.uk/efo/EFO_0009861 GCST008943 Genome-wide genotyping array 866 2019-10-25 31586183 Niazi Y 2019-10-04 Mutagenesis www.ncbi.nlm.nih.gov/pubmed/31586183 Distinct pathways associated with chromosomal aberration frequency in a cohort exposed to genotoxic compounds compared to general population. Chromosomal aberration frequency (chromosome type) 866 European and unknown ancestry individuals NA Illumina [> 2600000] (imputed) 4 chromosome-type aberration frequency http://www.ebi.ac.uk/efo/EFO_0009861 GCST008944 Genome-wide genotyping array 866 2019-10-25 31586183 Niazi Y 2019-10-04 Mutagenesis www.ncbi.nlm.nih.gov/pubmed/31586183 Distinct pathways associated with chromosomal aberration frequency in a cohort exposed to genotoxic compounds compared to general population. High chromosomal aberration frequency (total) in genotoxic compound exposure 342 European and unknown ancestry cases, 265 European and unknown ancestry controls NA Illumina [> 2600000] (imputed) 0 chromosomal aberration frequency http://www.ebi.ac.uk/efo/EFO_0009860 GCST008945 Genome-wide genotyping array 607 2019-10-25 31586183 Niazi Y 2019-10-04 Mutagenesis www.ncbi.nlm.nih.gov/pubmed/31586183 Distinct pathways associated with chromosomal aberration frequency in a cohort exposed to genotoxic compounds compared to general population. Chromosomal aberration frequency (total) in genotoxic compound exposure 607 European and unknown ancestry individuals NA Illumina [> 2600000] (imputed) 1 chromosomal aberration frequency http://www.ebi.ac.uk/efo/EFO_0009860 GCST008946 Genome-wide genotyping array 607 2019-10-25 31586183 Niazi Y 2019-10-04 Mutagenesis www.ncbi.nlm.nih.gov/pubmed/31586183 Distinct pathways associated with chromosomal aberration frequency in a cohort exposed to genotoxic compounds compared to general population. High chromosomal aberration frequency (chromatid type) in genotoxic compound exposure 345 European and unknown ancestry cases, 262 European and unknown ancestry controls NA Illumina [> 2600000] (imputed) 2 chromatid-type aberration frequency http://www.ebi.ac.uk/efo/EFO_0009862 GCST008947 Genome-wide genotyping array 607 2019-10-25 31586183 Niazi Y 2019-10-04 Mutagenesis www.ncbi.nlm.nih.gov/pubmed/31586183 Distinct pathways associated with chromosomal aberration frequency in a cohort exposed to genotoxic compounds compared to general population. Chromosomal aberration frequency (chromatid type) in genotoxic compound exposure 607 European and unknown ancestry individuals NA Illumina [> 2600000] (imputed) 4 chromatid-type aberration frequency http://www.ebi.ac.uk/efo/EFO_0009862 GCST008948 Genome-wide genotyping array 607 2019-10-25 31586183 Niazi Y 2019-10-04 Mutagenesis www.ncbi.nlm.nih.gov/pubmed/31586183 Distinct pathways associated with chromosomal aberration frequency in a cohort exposed to genotoxic compounds compared to general population. High chromosomal aberration frequency (chromosome type) in genotoxic compound exposure 321 European and unknown ancestry cases, 286 European and unknown ancestry controls NA Illumina [> 2600000] (imputed) 2 chromosome-type aberration frequency http://www.ebi.ac.uk/efo/EFO_0009861 GCST008949 Genome-wide genotyping array 607 2019-10-25 31586183 Niazi Y 2019-10-04 Mutagenesis www.ncbi.nlm.nih.gov/pubmed/31586183 Distinct pathways associated with chromosomal aberration frequency in a cohort exposed to genotoxic compounds compared to general population. Chromosomal aberration frequency (chromosome type) in genotoxic compound exposure 607 European and unknown ancestry individuals NA Illumina [> 2600000] (imputed) 2 chromosome-type aberration frequency http://www.ebi.ac.uk/efo/EFO_0009861 GCST008939 Genome-wide genotyping array 607 2019-10-25 31586183 Niazi Y 2019-10-04 Mutagenesis www.ncbi.nlm.nih.gov/pubmed/31586183 Distinct pathways associated with chromosomal aberration frequency in a cohort exposed to genotoxic compounds compared to general population. High chromosomal aberration frequency (total) 342 European and unknown ancestry genotoxic compound-exposed cases, 265 European and unknown ancestry genotoxic compound-exposed controls,255 European and unknown ancestry unexposed cases, 611 European and unknown ancestry unexposed controls NA Illumina [> 2600000] (imputed) 3 chromosomal aberration frequency http://www.ebi.ac.uk/efo/EFO_0009860 GCST008950 Genome-wide genotyping array 1473 2019-10-25 31586183 Niazi Y 2019-10-04 Mutagenesis www.ncbi.nlm.nih.gov/pubmed/31586183 Distinct pathways associated with chromosomal aberration frequency in a cohort exposed to genotoxic compounds compared to general population. Chromosomal aberration frequency (total) 607 European and unknown ancestry genotoxic compound-exposed individuals, 866 European and unknown ancestry unexposed individuals NA Illumina [> 2600000] (imputed) 2 chromosomal aberration frequency http://www.ebi.ac.uk/efo/EFO_0009860 GCST008951 Genome-wide genotyping array 1473 2019-10-25 31586183 Niazi Y 2019-10-04 Mutagenesis www.ncbi.nlm.nih.gov/pubmed/31586183 Distinct pathways associated with chromosomal aberration frequency in a cohort exposed to genotoxic compounds compared to general population. High chromosomal aberration frequency (chromatid type) 345 European and unknown ancestry genotoxic compound-exposed cases, 262 European and unknown ancestry genotoxic compound-exposed controls, 333 European and unknown ancestry unexposed cases, 533 European and unknown ancestry unexposed controls NA Illumina [> 2600000] (imputed) 3 chromatid-type aberration frequency http://www.ebi.ac.uk/efo/EFO_0009862 GCST008952 Genome-wide genotyping array 1473 2019-10-25 31586183 Niazi Y 2019-10-04 Mutagenesis www.ncbi.nlm.nih.gov/pubmed/31586183 Distinct pathways associated with chromosomal aberration frequency in a cohort exposed to genotoxic compounds compared to general population. Chromosomal aberration frequency (chromatid type) 607 European and unknown ancestry genotoxic compound-exposed individuals, 866 European and unknown ancestry unexposed individuals NA Illumina [> 2600000] (imputed) 3 chromatid-type aberration frequency http://www.ebi.ac.uk/efo/EFO_0009862 GCST008953 Genome-wide genotyping array 1473 2019-10-25 31586183 Niazi Y 2019-10-04 Mutagenesis www.ncbi.nlm.nih.gov/pubmed/31586183 Distinct pathways associated with chromosomal aberration frequency in a cohort exposed to genotoxic compounds compared to general population. High chromosomal aberration frequency (chromosome type) 321 European and unknown ancestry genotoxic compound-exposed cases, 286 European and unknown ancestry genotoxic compound-exposed controls, 333 European and unknown ancestry unexposed cases, 533 European and unknown ancestry unexposed controls NA Illumina [> 2600000] (imputed) 4 chromosome-type aberration frequency http://www.ebi.ac.uk/efo/EFO_0009861 GCST008954 Genome-wide genotyping array 1473 2019-10-25 31586183 Niazi Y 2019-10-04 Mutagenesis www.ncbi.nlm.nih.gov/pubmed/31586183 Distinct pathways associated with chromosomal aberration frequency in a cohort exposed to genotoxic compounds compared to general population. Chromosomal aberration frequency (chromosome type) 607 European and unknown ancestry genotoxic compound-exposed individuals, 866 European and unknown ancestry unexposed individuals NA Illumina [> 2600000] (imputed) 3 chromosome-type aberration frequency http://www.ebi.ac.uk/efo/EFO_0009861 GCST008955 Genome-wide genotyping array 1473 2019-10-25 31586183 Niazi Y 2019-10-04 Mutagenesis www.ncbi.nlm.nih.gov/pubmed/31586183 Distinct pathways associated with chromosomal aberration frequency in a cohort exposed to genotoxic compounds compared to general population. High chromosomal aberration frequency (total) 255 European and unknown ancestry cases, 611 European and unknown ancestry controls NA Illumina [> 2600000] (imputed) 3 chromosomal aberration frequency http://www.ebi.ac.uk/efo/EFO_0009860 GCST008956 Genome-wide genotyping array 866 2019-12-02 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Height 347,086 European ancestry individuals NA NR [5554549] (imputed) 0 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST009142 Genome-wide genotyping array 347086 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. BMI-adjusted waist-hip ratio variance 346,535 European ancestry individuals NA NR [5554549] (imputed) 0 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST009127 Genome-wide genotyping array 346535 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Body fat percentage variance 341,632 European ancestry individuals NA NR [5554549] (imputed) 5 body fat percentage http://www.ebi.ac.uk/efo/EFO_0007800 GCST009105 Genome-wide genotyping array 341632 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Basal metabolic rate variance 341,584 European ancestry individuals NA NR [5554549] (imputed) 5 base metabolic rate measurement http://www.ebi.ac.uk/efo/EFO_0007777 GCST009106 Genome-wide genotyping array 341584 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Body mass index variance 346,393 European ancestry individuals NA NR [5554549] (imputed) 22 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST009107 Genome-wide genotyping array 346393 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Waist circumference variance 347,158 European ancestry individuals NA NR [5554549] (imputed) 16 waist circumference http://www.ebi.ac.uk/efo/EFO_0004342 GCST009108 Genome-wide genotyping array 347158 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Hip circumference variance 346,781 European ancestry individuals NA NR [5554549] (imputed) 16 hip circumference http://www.ebi.ac.uk/efo/EFO_0005093 GCST009109 Genome-wide genotyping array 346781 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Waist-hip ratio variance 347,134 European ancestry individuals NA NR [5554549] (imputed) 1 waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0004343 GCST009110 Genome-wide genotyping array 347134 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Height variance 347,086 European ancestry individuals NA NR [5554549] (imputed) 0 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST009111 Genome-wide genotyping array 347086 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Lung function (forced vital capacity) variance 317,222 European ancestry individuals NA NR [5554549] (imputed) 0 vital capacity http://www.ebi.ac.uk/efo/EFO_0004312 GCST009112 Genome-wide genotyping array 317222 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Lung function (FEV1) variance 317,285 European ancestry individuals NA NR [5554549] (imputed) 0 forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0004314 GCST009113 Genome-wide genotyping array 317285 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Lung function (FEV1/FVC) variance 316,614 European ancestry individuals NA NR [5554549] (imputed) 3 FEV/FEC ratio http://www.ebi.ac.uk/efo/EFO_0004713 GCST009114 Genome-wide genotyping array 316614 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Heel bone mineral density variance 197,261 European ancestry individuals NA NR [5554549] (imputed) 6 heel bone mineral density http://www.ebi.ac.uk/efo/EFO_0009270 GCST009115 Genome-wide genotyping array 197261 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Birth weight variance 197,758 European ancestry individuals NA NR [5554549] (imputed) 1 birth weight http://www.ebi.ac.uk/efo/EFO_0004344 GCST009116 Genome-wide genotyping array 197758 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Lung function (forced vital capacity) 317,222 European ancestry individuals NA NR [5554549] (imputed) 0 vital capacity http://www.ebi.ac.uk/efo/EFO_0004312 GCST009117 Genome-wide genotyping array 317222 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Lung function (FEV1) 317,285 European ancestry individuals NA NR [5554549] (imputed) 0 forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0004314 GCST009118 Genome-wide genotyping array 317285 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Lung function (FEV1/FVC) 316,614 European ancestry individuals NA NR [5554549] (imputed) 3 FEV/FEC ratio http://www.ebi.ac.uk/efo/EFO_0004713 GCST009119 Genome-wide genotyping array 316614 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Heel bone mineral density 197,261 European ancestry individuals NA NR [5554549] (imputed) 6 heel bone mineral density http://www.ebi.ac.uk/efo/EFO_0009270 GCST009120 Genome-wide genotyping array 197261 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Birth weight 197,758 European ancestry individuals NA NR [5554549] (imputed) 1 birth weight http://www.ebi.ac.uk/efo/EFO_0004344 GCST009128 Genome-wide genotyping array 197758 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Body mass index 346,393 European ancestry individuals NA NR [5554549] (imputed) 22 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST009121 Genome-wide genotyping array 346393 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Waist circumference 347,158 European ancestry individuals NA NR [5554549] (imputed) 13 waist circumference http://www.ebi.ac.uk/efo/EFO_0004342 GCST009122 Genome-wide genotyping array 347158 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Hip circumference 346,781 European ancestry individuals NA NR [5554549] (imputed) 16 hip circumference http://www.ebi.ac.uk/efo/EFO_0005093 GCST009123 Genome-wide genotyping array 346781 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Waist-hip ratio 347,134 European ancestry individuals NA NR [5554549] (imputed) 1 waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0004343 GCST009124 Genome-wide genotyping array 347134 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Waist-to-hip ratio adjusted for BMI 346,535 European ancestry individuals NA NR [5554549] (imputed) 0 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST009125 Genome-wide genotyping array 346535 2019-11-27 31453325 Wang H 2019-08-14 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31453325 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Body fat percentage 341,632 European ancestry individuals NA NR [5554549] (imputed) 3 body fat percentage http://www.ebi.ac.uk/efo/EFO_0007800 GCST009126 Genome-wide genotyping array 341632 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Corpus callosum anterior volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 9 corpus callosum anterior volume measurement http://www.ebi.ac.uk/efo/EFO_0010295 GCST009220 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Cortex volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 11 brain cortex volume measurement http://www.ebi.ac.uk/efo/EFO_0010287 GCST009197 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Cerebral white matter volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 12 white matter volume measurement http://www.ebi.ac.uk/efo/EFO_0008320 GCST009206 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Sub-cortical grey matter volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 14 grey matter volume measurement http://www.ebi.ac.uk/efo/EFO_0005420 GCST009201 Genome-wide genotyping array 777 2019-12-13 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Total grey matter volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 12 grey matter volume measurement http://www.ebi.ac.uk/efo/EFO_0005420 GCST009263 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Whole brain grey matter density 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 21 Grey matter density measurement http://www.ebi.ac.uk/efo/EFO_0010306 GCST009200 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Total intracranial volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 18 intracranial volume measurement http://www.ebi.ac.uk/efo/EFO_0004886 GCST009204 Genome-wide genotyping array 777 2019-12-13 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Cerebellum white matter volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 11 white matter volume measurement http://www.ebi.ac.uk/efo/EFO_0008320 GCST009254 Genome-wide genotyping array 777 2019-12-06 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Cerebellum cortex volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 17 cerebellum cortex volume measurement http://www.ebi.ac.uk/efo/EFO_0010291 GCST009203 Genome-wide genotyping array 777 2019-12-13 31530798 Alliey-Rodriguez N 2019-09-17 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31530798 NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis. Superior temporal sulcus banks volume 87 European ancestry Schizophrenia cases, 85 African American Schizophrenia cases, 15 Schizophrenia cases, 67 European ancestry Schizoaffective disorder cases, 53 African American Schizoaffective disorder cases, 7 Schizoaffective disorder cases, 130 European ancestry Bipolar disorders cases, 33 African American Bipolar disorders cases, 6 Bipolar disorders cases, 199 European ancestry controls, 79 African American controls, 16 controls NA Illumina [4322238] (imputed) 13 banks of the superior temporal sulcus volume measurement http://www.ebi.ac.uk/efo/EFO_0010286 GCST009256 Genome-wide genotyping array 777 2019-05-07 30475886 Mekli K 2018-11-26 PLoS One www.ncbi.nlm.nih.gov/pubmed/30475886 Frailty Index associates with GRIN2B in two representative samples from the United States and the United Kingdom. Frailty index 8,232 European ancestry individuals 5,248 European ancestry individuals Illumina [at least 1215858] 0 frailty measurement http://www.ebi.ac.uk/efo/EFO_0009885 GCST007716 Genome-wide genotyping array 8232 2020-02-12 31589552 Lind L 2019-10-07 Metab Syndr Relat Disord www.ncbi.nlm.nih.gov/pubmed/31589552 Genome-Wide Association Study of the Metabolic Syndrome in UK Biobank. Metabolic syndrome 291,107 European ancestry individuals NA Affymetrix [9463307] (imputed) 93 metabolic syndrome http://www.ebi.ac.uk/efo/EFO_0000195 GCST009602 Genome-wide genotyping array 291107 2019-10-23 31519223 Scepanovic P 2019-09-13 Microbiome www.ncbi.nlm.nih.gov/pubmed/31519223 A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals. Gut microbiota (beta diversity) 858 Metropolitan French ancestry individuals NA Illumina [5293637] (imputed) 47 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST008901 Genome-wide genotyping array, Exome genotyping array 858 2019-10-23 31519223 Scepanovic P 2019-09-13 Microbiome www.ncbi.nlm.nih.gov/pubmed/31519223 A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals. Gut microbiota (alpha diversity) 858 Metropolitan French ancestry individuals NA Illumina [5293637] (imputed) 47 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST008900 Genome-wide genotyping array, Exome genotyping array 858 2019-10-23 31519223 Scepanovic P 2019-09-13 Microbiome www.ncbi.nlm.nih.gov/pubmed/31519223 A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals. Gut microbiota relative abundance (bacterial taxa) up to 858 Metropolitan French ancestry individuals NA Illumina [5293637] (imputed) 58 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST008903 Genome-wide genotyping array, Exome genotyping array 858 2019-10-23 31519223 Scepanovic P 2019-09-13 Microbiome www.ncbi.nlm.nih.gov/pubmed/31519223 A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals. Gut microbiota (bacterial taxa) 858 Metropolitan French ancestry individuals NA Illumina [5293637] (imputed) 23 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST008902 Genome-wide genotyping array, Exome genotyping array 858 2019-12-17 31596458 Greenwood TA 2019-10-09 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/31596458 Genome-wide Association of Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia (COGS) Study. Abstraction and mental flexibility 523 European ancestry schizophrenia cases, 100 Latino schizophrenia cases, 827 European ancestry controls, 83 Latino controls NA Illumina [> 6200000] (imputed) 19 executive function measurement http://www.ebi.ac.uk/efo/EFO_0009332 GCST009303 Genome-wide genotyping array 1533 2019-12-17 31596458 Greenwood TA 2019-10-09 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/31596458 Genome-wide Association of Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia (COGS) Study. Emotional recognition 523 European ancestry schizophrenia cases, 100 Latino schizophrenia cases, 827 European ancestry controls, 83 Latino controls NA NR [> 6200000] (imputed) 9 cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0008354 GCST009308 Genome-wide genotyping array 1533 2019-12-17 31596458 Greenwood TA 2019-10-09 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/31596458 Genome-wide Association of Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia (COGS) Study. Face memory 523 European ancestry schizophrenia cases, 100 Latino schizophrenia cases, 827 European ancestry controls, 83 Latino controls NA Illumina [> 6200000] (imputed) 13 memory performance http://www.ebi.ac.uk/efo/EFO_0004874 GCST009309 Genome-wide genotyping array 1533 2019-12-17 31596458 Greenwood TA 2019-10-09 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/31596458 Genome-wide Association of Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia (COGS) Study. Sensorimotor dexterity 523 European ancestry schizophrenia cases, 100 Latino schizophrenia cases, 827 European ancestry controls, 83 Latino controls NA Illumina [> 6200000] (imputed) 35 cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0008354 GCST009310 Genome-wide genotyping array 1533 2019-12-17 31596458 Greenwood TA 2019-10-09 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/31596458 Genome-wide Association of Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia (COGS) Study. Spatial memory 523 European ancestry schizophrenia cases, 100 Latino schizophrenia cases, 827 European ancestry controls, 83 Latino controls NA Illumina [> 6200000] (imputed) 20 memory performance http://www.ebi.ac.uk/efo/EFO_0004874 GCST009307 Genome-wide genotyping array 1533 2019-12-17 31596458 Greenwood TA 2019-10-09 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/31596458 Genome-wide Association of Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia (COGS) Study. Spatial processing 523 European ancestry schizophrenia cases, 100 Latino schizophrenia cases, 827 European ancestry controls, 83 Latino controls NA Illumina [> 6200000] (imputed) 23 cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0008354 GCST009306 Genome-wide genotyping array 1533 2019-12-17 31596458 Greenwood TA 2019-10-09 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/31596458 Genome-wide Association of Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia (COGS) Study. California verbal learning test score 523 European ancestry schizophrenia cases, 100 Latino schizophrenia cases, 827 European ancestry controls, 83 Latino controls NA Illumina [> 6200000] (imputed) 17 memory performance http://www.ebi.ac.uk/efo/EFO_0004874 GCST009305 Genome-wide genotyping array 1533 2019-12-17 31596458 Greenwood TA 2019-10-09 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/31596458 Genome-wide Association of Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia (COGS) Study. Degraded stimulus continuous performance test score 523 European ancestry schizophrenia cases, 100 Latino schizophrenia cases, 827 European ancestry controls, 83 Latino controls NA Illumina [> 6200000] (imputed) 16 attention function measurement http://www.ebi.ac.uk/efo/EFO_0007636 GCST009304 Genome-wide genotyping array 1533 2019-12-17 31596458 Greenwood TA 2019-10-09 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/31596458 Genome-wide Association of Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia (COGS) Study. Letter-number span reordering 523 European ancestry schizophrenia cases, 100 Latino schizophrenia cases, 827 European ancestry controls, 83 Latino controls NA Illumina [> 6200000] (imputed) 9 memory performance http://www.ebi.ac.uk/efo/EFO_0004874 GCST009311 Genome-wide genotyping array 1533 2019-12-17 31596458 Greenwood TA 2019-10-09 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/31596458 Genome-wide Association of Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia (COGS) Study. Prepulse inhibition of the startle response 523 European ancestry schizophrenia cases, 100 Latino schizophrenia cases, 827 European ancestry controls, 83 Latino controls NA Illumina [> 6200000] (imputed) 10 cognitive inhibition measurement http://www.ebi.ac.uk/efo/EFO_0007969 GCST009313 Genome-wide genotyping array 1533 2019-12-17 31596458 Greenwood TA 2019-10-09 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/31596458 Genome-wide Association of Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia (COGS) Study. Antisaccade task score 523 European ancestry schizophrenia cases, 100 Latino schizophrenia cases, 827 European ancestry controls, 83 Latino controls NA Illumina [> 6200000] (imputed) 24 cognitive inhibition measurement http://www.ebi.ac.uk/efo/EFO_0007969 GCST009312 Genome-wide genotyping array 1533 2019-09-29 31476763 Otsuka I 2019-09-02 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/31476763 Genome-wide association studies identify polygenic effects for completed suicide in the Japanese population. Age at suicide 719 Japanese ancestry individuals NA Illumina [8810873] (imputed) 3 suicide behaviour measurement http://www.ebi.ac.uk/efo/EFO_0006882 GCST008771 Genome-wide genotyping array 719 2019-09-29 31476763 Otsuka I 2019-09-02 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/31476763 Genome-wide association studies identify polygenic effects for completed suicide in the Japanese population. Suicide 746 Japanese ancestry cases, 14,049 Japanese ancestry controls NA Illumina [8625325] (imputed) 6 suicide http://www.ebi.ac.uk/efo/EFO_0007624 GCST008772 Genome-wide genotyping array 14795 2019-10-21 31430377 Chung J 2019-08-20 Brain www.ncbi.nlm.nih.gov/pubmed/31430377 Genome-wide association study of cerebral small vessel disease reveals established and novel loci. Non-lobar intracerebral hemorrhage 1,005 European ancestry cases, 1,711 European ancestry controls NA Affymetrix, Illumina [39235000] (imputed) 2 non-lobar intracerebral hemorrhage http://www.ebi.ac.uk/efo/EFO_0010178 GCST008873 Genome-wide genotyping array 2716 2019-10-21 31430377 Chung J 2019-08-20 Brain www.ncbi.nlm.nih.gov/pubmed/31430377 Genome-wide association study of cerebral small vessel disease reveals established and novel loci. Lobar intracerebral hemorrhage 755 European ancestry cases, 1,711 European ancestry controls NA Affymetrix, Illumina [39235000] (imputed) 1 lobar intracerebral hemorrhage http://www.ebi.ac.uk/efo/EFO_0010177 GCST008874 Genome-wide genotyping array 2466 2019-10-21 31430377 Chung J 2019-08-20 Brain www.ncbi.nlm.nih.gov/pubmed/31430377 Genome-wide association study of cerebral small vessel disease reveals established and novel loci. Intracerebral hemorrhage (MTAG) at least 1,808 European ancestry cases, at least 1,711 European ancestry controls NA Affymetrix, Illumina [39235000] (imputed) 0 intracerebral hemorrhage http://www.ebi.ac.uk/efo/EFO_0005669 GCST008875 Genome-wide genotyping array 3519 2019-10-21 31430377 Chung J 2019-08-20 Brain www.ncbi.nlm.nih.gov/pubmed/31430377 Genome-wide association study of cerebral small vessel disease reveals established and novel loci. Non-lobar intracerebral hemorrhage (MTAG) at least 1,005 European ancestry cases, at least 1,711 European ancestry controls NA Affymetrix, Illumina [39235000] (imputed) 42 non-lobar intracerebral hemorrhage http://www.ebi.ac.uk/efo/EFO_0010178 GCST008876 Genome-wide genotyping array 2716 2019-10-21 31430377 Chung J 2019-08-20 Brain www.ncbi.nlm.nih.gov/pubmed/31430377 Genome-wide association study of cerebral small vessel disease reveals established and novel loci. Lobar intracerebral hemorrhage (MTAG) at least 755 European ancestry cases, at least 1,711 European ancestry controls NA Affymetrix, Illumina [39235000] (imputed) 0 lobar intracerebral hemorrhage http://www.ebi.ac.uk/efo/EFO_0010177 GCST008877 Genome-wide genotyping array 2466 2019-10-21 31430377 Chung J 2019-08-20 Brain www.ncbi.nlm.nih.gov/pubmed/31430377 Genome-wide association study of cerebral small vessel disease reveals established and novel loci. Intracerebral hemorrhage 1,808 European ancestry cases, 1,711 European ancestry controls NA Affymetrix, Illumina [39235000] (imputed) 0 intracerebral hemorrhage http://www.ebi.ac.uk/efo/EFO_0005669 GCST008878 Genome-wide genotyping array 3519 2019-10-16 27130862 Sarnowski C 2016-04-06 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/27130862 Identification of a new locus at 16q12 associated with time to asthma onset. Asthma (time to onset) 5,462 European ancestry cases, 8,424 European ancestry controls NA Illumina [2387926] (imputed) 10 age at onset, asthma http://www.ebi.ac.uk/efo/EFO_0004847, http://www.ebi.ac.uk/efo/EFO_0000270 GCST008838 Genome-wide genotyping array 13886 2019-10-16 30955190 Yun S 2019-04-06 Clin Exp Nephrol www.ncbi.nlm.nih.gov/pubmed/30955190 Genetic risk score raises the risk of incidence of chronic kidney disease in Korean general population-based cohort. Estimated glomerular filtration rate reduction (30%) up to 3,617 Korean ancestry individuals NA Affymetrix [up to 1590162] (imputed) 5 glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0005208 GCST008837 Genome-wide genotyping array 3617 2019-05-08 30955190 Yun S 2019-04-06 Clin Exp Nephrol www.ncbi.nlm.nih.gov/pubmed/30955190 Genetic risk score raises the risk of incidence of chronic kidney disease in Korean general population-based cohort. Incident chronic kidney disease 281 Korean ancestry cases, 3,336 Korean ancestry controls NA Affymetrix [up to 1590162] (imputed) 2 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST007734 Genome-wide genotyping array 3617 2019-08-22 25489960 Yang SK 2015-01-01 Inflamm Bowel Dis www.ncbi.nlm.nih.gov/pubmed/25489960 Immunochip analysis identification of 6 additional susceptibility loci for Crohn's disease in Koreans. Crohn's disease 722 Korean ancestry cases, 461 Korean ancestry controls 948 Korean ancestry cases, 977 Korean ancestry controls Illumina [549616] (imputed) 6 Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000384 GCST008485 Targeted genotyping array [ImmunoChip] 1183 2019-10-21 31598132 Donati G 2019-06-30 Mind Brain Educ www.ncbi.nlm.nih.gov/pubmed/31598132 Genome-Wide Association Study of Latent Cognitive Measures in Adolescence: Genetic Overlap With Intelligence and Education. Cognitive performance (processing speed) 4,611 European ancestry adolescents NA Illumina [6319684] (imputed) 22 information processing speed http://www.ebi.ac.uk/efo/EFO_0004363 GCST008891 Genome-wide genotyping array 4611 2019-10-21 31598132 Donati G 2019-06-30 Mind Brain Educ www.ncbi.nlm.nih.gov/pubmed/31598132 Genome-Wide Association Study of Latent Cognitive Measures in Adolescence: Genetic Overlap With Intelligence and Education. Working memory 4,611 European ancestry adolescents NA Illumina [6319684] (imputed) 18 short-term memory http://www.ebi.ac.uk/efo/EFO_0004335 GCST008892 Genome-wide genotyping array 4611 2019-10-21 31598132 Donati G 2019-06-30 Mind Brain Educ www.ncbi.nlm.nih.gov/pubmed/31598132 Genome-Wide Association Study of Latent Cognitive Measures in Adolescence: Genetic Overlap With Intelligence and Education. Inhibitory control 4,611 European ancestry adolescents NA Illumina [6319684] (imputed) 0 behavioural inhibitory control measurement http://www.ebi.ac.uk/efo/EFO_0008467 GCST008893 Genome-wide genotyping array 4611 2020-01-08 31597885 Nakano MH 2019-10-09 Biol Pharm Bull www.ncbi.nlm.nih.gov/pubmed/31597885 A Genome-Wide Association Study Identifies Five Novel Genetic Markers for Trastuzumab-Induced Cardiotoxicity in Japanese Population. Trastuzumab-induced cardiotoxicity in cancer 11 Japanese ancestry cases, 257 Japanese ancestry controls 14 Japanese ancestry cases, 199 Japanese ancestry controls Illumina [543807] 1 response to trastuzumab, cardiotoxicity http://www.ebi.ac.uk/efo/EFO_0008347, http://www.ebi.ac.uk/efo/EFO_1001482 GCST009381 Genome-wide genotyping array 268 2019-12-17 31594949 Nievergelt CM 2019-10-08 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31594949 International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci. Post-traumatic stress disorder 23,212 European ancestry cases, 4,363 African ancestry cases, 1,981 Latino and Native American ancestry cases, 151,447 European ancestry controls, 10,976 African ancestry controls, 3,722 Latino and Native American ancestry controls NA Affymetrix, Illumina [~ 1175791] (imputed) 7 post-traumatic stress disorder http://www.ebi.ac.uk/efo/EFO_0001358 GCST009315 Genome-wide genotyping array 195701 2019-10-28 31591379 Sun Y 2019-10-07 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31591379 Genome-wide association study of alcohol dependence in male Han Chinese and cross-ethnic polygenic risk score comparison. Alcohol dependence 533 Han Chinese ancestry cases, 2,848 Han Chinese ancestry controls 146 Han Chinese ancestry cases, 200 Han Chinese ancestry controls Illumina [6449738] (imputed) 2 alcohol dependence http://www.ebi.ac.uk/efo/EFO_0003829 GCST008966 Genome-wide genotyping array 3381 2019-10-24 31587654 Torres-Aguila NP 2019-10-07 Stroke www.ncbi.nlm.nih.gov/pubmed/31587654 Genome-Wide Association Study of White Blood Cell Counts in Patients With Ischemic Stroke. Leukocyte count in ischemic stroke 2,064 Spanish ancestry individuals 407 European ancestry individuals Illumina [7340003] (imputed) 1 leukocyte count http://www.ebi.ac.uk/efo/EFO_0004308 GCST008915 Genome-wide genotyping array 2064 2020-01-16 31600487 Sazonovs A 2019-10-05 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/31600487 HLA-DQA1*05 Carriage Associated With Development of Anti-Drug Antibodies to Infliximab and Adalimumab in Patients With Crohn's Disease. Immunogenicity to anti-TNF therapy in Crohn's disease 1,240 European ancestry individuals 107 European ancestry individuals Illumina [7578947] (imputed) 0 response to TNF antagonist, anti-drug antibody measurement http://www.ebi.ac.uk/efo/EFO_0004653, http://www.ebi.ac.uk/efo/EFO_0010559 GCST009445 Genome-wide genotyping array 1240 2019-11-04 31596875 Traylor M 2019-10-09 PLoS One www.ncbi.nlm.nih.gov/pubmed/31596875 Genetic associations with radiological damage in rheumatoid arthritis: Meta-analysis of seven genome-wide association studies of 2,775 cases. Joint damage in rheumatoid arthritis 2,527 European ancestry individuals, 196 African ancestry individuals, 52 individuals NA Affymetrix, Illumina [4802696] (imputed) 16 joint damage measurement http://www.ebi.ac.uk/efo/EFO_0005413 GCST008992 Genome-wide genotyping array, Targeted genotyping array 2775 2019-11-04 31596875 Traylor M 2019-10-09 PLoS One www.ncbi.nlm.nih.gov/pubmed/31596875 Genetic associations with radiological damage in rheumatoid arthritis: Meta-analysis of seven genome-wide association studies of 2,775 cases. Joint damage in rheumatoid arthritis 2,527 European ancestry individuals NA Affymetrix, Illumina [2723488] (imputed) 14 joint damage measurement http://www.ebi.ac.uk/efo/EFO_0005413 GCST008993 Genome-wide genotyping array, Targeted genotyping array 2527 2019-10-23 31564439 Fang H 2019-09-26 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31564439 Harmonizing Genetic Ancestry and Self-identified Race/Ethnicity in Genome-wide Association Studies. Height up to 248,507 non-Hispanic white individuals, up to 68,155 non-Hispanic black individuals, up to 25,847 Hispanic individuals, up to 3,054 Asian ancestry individuals NA Affymetrix [723305] 39 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST008904 Genome-wide genotyping array 345563 2020-01-13 31537701 Obeidat M 2019-09-19 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/31537701 The Pharmacogenomics of Inhaled Corticosteroids and Lung Function Decline in COPD. FEV1 decline rate x corticosteroid treatment interaction in chronic obstructive pulmonary disease 401 European ancestry drug-treated cases, 401 European ancestry placebo-treated cases 163 drug-treated cases, 36 placebo-treated cases Illumina [6559489] (imputed) 0 FEV change measurement, response to corticosteroid http://www.ebi.ac.uk/efo/EFO_0005921, http://purl.obolibrary.org/obo/GO_0031960 GCST009428 Genome-wide genotyping array 802 2019-10-08 31319653 Jeon C 2019-07-12 Epidemiol Health www.ncbi.nlm.nih.gov/pubmed/31319653 Bilirubin and risk of ischemic heart disease in Korea: A two-sample Mendelian randomization study. Ischemic heart disease 1,910 Korean ancestry cases, 11,945 Korean ancestry controls NA NR [at least 830000] (imputed) 0 Myocardial Ischemia http://www.ebi.ac.uk/efo/EFO_1001375 GCST008816 Genome-wide genotyping array 13855 2019-10-08 31319653 Jeon C 2019-07-12 Epidemiol Health www.ncbi.nlm.nih.gov/pubmed/31319653 Bilirubin and risk of ischemic heart disease in Korea: A two-sample Mendelian randomization study. Bilirubin levels 33,598 Korean ancestry individuals NA NR [at least 830000] (imputed) 5 bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004570 GCST008817 Genome-wide genotyping array 33598 2019-10-23 31579629 Fiorica PN 2019-09-26 PeerJ www.ncbi.nlm.nih.gov/pubmed/31579629 Transcriptome association studies of neuropsychiatric traits in African Americans implicate PRMT7 in schizophrenia. Bipolar disorder 671 African American cases, 348 African American controls NA Affymetrix [12799548] (imputed) 1 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST008905 Genome-wide genotyping array 1019 2019-10-23 31579629 Fiorica PN 2019-09-26 PeerJ www.ncbi.nlm.nih.gov/pubmed/31579629 Transcriptome association studies of neuropsychiatric traits in African Americans implicate PRMT7 in schizophrenia. Schizophrenia 969 African American cases, 1,287 African American controls NA Affymetrix [12780487] (imputed) 2 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST008906 Genome-wide genotyping array 2256 2019-08-07 31152121 Zhu M 2019-05-31 Diabetes Care www.ncbi.nlm.nih.gov/pubmed/31152121 Identification of Novel T1D Risk Loci and Their Association With Age and Islet Function at Diagnosis in Autoantibody-Positive T1D Individuals: Based on a Two-Stage Genome-Wide Association Study. Type 1 diabetes 1,005 Han Chinese ancestry cases, 1,257 Han Chinese ancestry controls 1,378 Han Chinese ancestry cases, 3,774 Han Chinese ancestry controls Illumina [787224] (imputed) 5 type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001359 GCST008377 Genome-wide genotyping array 2262 2019-09-18 31151762 Gelernter J 2019-04-08 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/31151762 Genome-wide Association Study of Maximum Habitual Alcohol Intake in >140,000 U.S. European and African American Veterans Yields Novel Risk Loci. Maximum habitual alcohol consumption 126,936 European ancestry individuals, 17,029 African American individuals NA Affymetrix [up to 6007810] (imputed) 37 alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0007878 GCST008675 Genome-wide genotyping array 143965 2019-08-06 31171785 Dorajoo R 2019-06-06 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31171785 Loci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studies. Leukocyte telomere length 16,759 Singaporean Han Chinese ancestry individuals 6,337 Singaporean Chinese ancestry individuals, up to 37,505 European ancestry individuals Illumina [6407959] (imputed) 24 telomere length http://www.ebi.ac.uk/efo/EFO_0004505 GCST008366 Genome-wide genotyping array 16759 2019-10-16 31530331 Thorp JG 2019-09-18 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31530331 Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Depressive symptom (depressed mood) (binary trait) 32,263 European ancestry cases, 116,489 European ancestry controls NA NR [9413637] (imputed) 1 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST008840 Genome-wide genotyping array 148752 2019-10-16 31530331 Thorp JG 2019-09-18 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31530331 Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Depressive symptom (sleep problems) (binary trait) 72,302 European ancestry cases, 76,450 European ancestry controls NA NR [9413637] (imputed) 3 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST008841 Genome-wide genotyping array 148752 2019-10-16 31530331 Thorp JG 2019-09-18 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31530331 Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Depressive symptom (fatigue) (binary trait) 73,924 European ancestry cases, 74,828 European ancestry controls NA NR [9413637] (imputed) 0 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST008842 Genome-wide genotyping array 148752 2019-10-16 31530331 Thorp JG 2019-09-18 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31530331 Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Depressive symptom (appetite changes) (binary trait) 26,757 European ancestry cases, 121,995 European ancestry controls NA NR [9413637] (imputed) 1 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST008843 Genome-wide genotyping array 148752 2019-10-16 31530331 Thorp JG 2019-09-18 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31530331 Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Depressive symptom (low self-esteem) (binary trait) 28,206 European ancestry cases, 120,546 European ancestry controls NA NR [9413637] (imputed) 0 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST008844 Genome-wide genotyping array 148752 2019-10-17 31530331 Thorp JG 2019-09-18 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31530331 Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Depressive symptom (concentration problems) (binary trait) 26,229 European ancestry cases, 122,523 European ancestry controls NA NR [9413637] (imputed) 0 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST008845 Genome-wide genotyping array 148752 2019-10-17 31530331 Thorp JG 2019-09-18 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31530331 Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Depressive symptom (psychomotor changes) (binary trait) 7,914 European ancestry cases, 140,838 European ancestry controls NA NR [9413637] (imputed) 0 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST008846 Genome-wide genotyping array 148752 2019-10-17 31530331 Thorp JG 2019-09-18 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31530331 Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Depressive symptom (suicidal ideation) (binary trait) 6,064 European ancestry cases, 142,688 European ancestry controls NA NR [9413637] (imputed) 0 suicide ideation measurement http://www.ebi.ac.uk/efo/EFO_0007619 GCST008847 Genome-wide genotyping array 148752 2019-10-17 31530331 Thorp JG 2019-09-18 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31530331 Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Depressive symptoms (binary sum-score) 148,752 European ancestry individuals NA NR [9413637] (imputed) 4 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST008849 Genome-wide genotyping array 148752 2019-10-17 31530331 Thorp JG 2019-09-18 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31530331 Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Depressive symptoms (sum-score) 148,752 European ancestry individuals NA NR [9413637] (imputed) 2 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST008848 Genome-wide genotyping array 148752 2019-10-17 31530331 Thorp JG 2019-09-18 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31530331 Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Depressive symptom (sleep problems) (ordinal trait) 148,752 European ancestry individuals NA NR [9413637] (imputed) 0 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST008850 Genome-wide genotyping array 148752 2019-10-17 31530331 Thorp JG 2019-09-18 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31530331 Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Depressive symptom (fatigue) (ordinal trait) 148,752 European ancestry individuals NA NR [9413637] (imputed) 5 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST008851 Genome-wide genotyping array 148752 2019-10-17 31530331 Thorp JG 2019-09-18 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31530331 Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Depressive symptom (appetite changes) (ordinal trait) 148,752 European ancestry individuals NA NR [9413637] (imputed) 0 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST008852 Genome-wide genotyping array 148752 2019-10-17 31530331 Thorp JG 2019-09-18 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31530331 Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Depressive symptom (low self-esteem) (ordinal trait) 148,752 European ancestry individuals NA NR [9413637] (imputed) 1 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST008853 Genome-wide genotyping array 148752 2019-10-17 31530331 Thorp JG 2019-09-18 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31530331 Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Depressive symptom (concentration problems) (ordinal trait) 148,752 European ancestry individuals NA NR [9413637] (imputed) 0 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST008854 Genome-wide genotyping array 148752 2019-10-17 31530331 Thorp JG 2019-09-18 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31530331 Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Depressive symptom (psychomotor changes) (ordinal trait) 148,752 European ancestry individuals NA NR [9413637] (imputed) 0 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST008855 Genome-wide genotyping array 148752 2019-10-17 31530331 Thorp JG 2019-09-18 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31530331 Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Depressive symptom (suicidal ideation) (ordinal trait) 148,752 European ancestry individuals NA NR [9413637] (imputed) 0 suicide ideation measurement http://www.ebi.ac.uk/efo/EFO_0007619 GCST008856 Genome-wide genotyping array 148752 2019-10-17 31530331 Thorp JG 2019-09-18 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31530331 Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Depressive symptom (anhedonia) (ordinal trait) 148,752 European ancestry individuals NA NR [9413637] (imputed) 2 anhedonia measurement http://www.ebi.ac.uk/efo/EFO_0009587 GCST008857 Genome-wide genotyping array 148752 2019-10-17 31530331 Thorp JG 2019-09-18 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31530331 Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Depressive symptom (depressed mood) (ordinal trait) 148,752 European ancestry individuals NA NR [9413637] (imputed) 1 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST008858 Genome-wide genotyping array 148752 2019-10-17 31530331 Thorp JG 2019-09-18 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31530331 Genetic heterogeneity in self-reported depressive symptoms identified through genetic analyses of the PHQ-9. Depressive symptom (anhedonia) (binary trait) 27,288 European ancestry cases, 121,464 European ancestry controls NA NR [9413637] (imputed) 2 anhedonia measurement http://www.ebi.ac.uk/efo/EFO_0009587 GCST008859 Genome-wide genotyping array 148752 2019-10-25 31551469 Tabassum R 2019-09-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31551469 Genetic architecture of human plasma lipidome and its link to cardiovascular disease. Triacylglyceride levels 2,045 European ancestry individuals NA Illumina [~ 9300000] (imputed) 21 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST008922 Genome-wide genotyping array 2045 2019-10-25 31551469 Tabassum R 2019-09-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31551469 Genetic architecture of human plasma lipidome and its link to cardiovascular disease. Ceramide levels 2,045 European ancestry individuals NA Illumina [~ 9300000] (imputed) 7 ceramide measurement http://www.ebi.ac.uk/efo/EFO_0010222 GCST008923 Genome-wide genotyping array 2045 2019-10-25 31551469 Tabassum R 2019-09-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31551469 Genetic architecture of human plasma lipidome and its link to cardiovascular disease. Diacylglyceride levels 2,045 European ancestry individuals NA Illumina [~ 9300000] (imputed) 2 diglyceride measurement http://www.ebi.ac.uk/efo/EFO_0010223 GCST008924 Genome-wide genotyping array 2045 2019-10-25 31551469 Tabassum R 2019-09-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31551469 Genetic architecture of human plasma lipidome and its link to cardiovascular disease. Lysophosphatidylcholine levels 2,045 European ancestry individuals NA Illumina [~ 9300000] (imputed) 16 lysophosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010224 GCST008925 Genome-wide genotyping array 2045 2019-10-25 31551469 Tabassum R 2019-09-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31551469 Genetic architecture of human plasma lipidome and its link to cardiovascular disease. Lysophosphatidylethanolamine levels 2,045 European ancestry individuals NA Illumina [~ 9300000] (imputed) 7 lysophosphatidylethanolamine measurement http://www.ebi.ac.uk/efo/EFO_0010225 GCST008926 Genome-wide genotyping array 2045 2019-10-25 31551469 Tabassum R 2019-09-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31551469 Genetic architecture of human plasma lipidome and its link to cardiovascular disease. Phosphatidylcholine levels 2,045 European ancestry individuals NA Illumina [~ 9300000] (imputed) 25 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST008927 Genome-wide genotyping array 2045 2019-10-25 31551469 Tabassum R 2019-09-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31551469 Genetic architecture of human plasma lipidome and its link to cardiovascular disease. Phosphatidylcholine-ether levels 2,045 European ancestry individuals NA Illumina [~ 9300000] (imputed) 10 phosphatidylcholine ether measurement http://www.ebi.ac.uk/efo/EFO_0010227 GCST008928 Genome-wide genotyping array 2045 2019-10-25 31551469 Tabassum R 2019-09-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31551469 Genetic architecture of human plasma lipidome and its link to cardiovascular disease. Phosphatidylethanolamine levels 2,045 European ancestry individuals NA Illumina [~ 9300000] (imputed) 12 phosphatidylethanolamine measurement http://www.ebi.ac.uk/efo/EFO_0010228 GCST008929 Genome-wide genotyping array 2045 2019-10-25 31551469 Tabassum R 2019-09-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31551469 Genetic architecture of human plasma lipidome and its link to cardiovascular disease. Phosphatidylethanolamine-ether levels 2,045 European ancestry individuals NA Illumina [~ 9300000] (imputed) 4 phosphatidylethanolamine ether measurement http://www.ebi.ac.uk/efo/EFO_0010229 GCST008930 Genome-wide genotyping array 2045 2019-10-25 31551469 Tabassum R 2019-09-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31551469 Genetic architecture of human plasma lipidome and its link to cardiovascular disease. Phosphatidylinositol levels 2,045 European ancestry individuals NA Illumina [~ 9300000] (imputed) 9 phosphatidylinositol measurement http://www.ebi.ac.uk/efo/EFO_0010230 GCST008931 Genome-wide genotyping array 2045 2019-10-25 31551469 Tabassum R 2019-09-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31551469 Genetic architecture of human plasma lipidome and its link to cardiovascular disease. Cholesteryl ester levels 2,045 European ancestry individuals NA Illumina [~ 9300000] (imputed) 11 esterified cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0008589 GCST008932 Genome-wide genotyping array 2045 2019-10-25 31551469 Tabassum R 2019-09-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31551469 Genetic architecture of human plasma lipidome and its link to cardiovascular disease. Sphingomyelin levels 2,045 European ancestry individuals NA Illumina [~ 9300000] (imputed) 22 sphingomyelin measurement http://www.ebi.ac.uk/efo/EFO_0010118 GCST008933 Genome-wide genotyping array 2045 2019-10-25 31551469 Tabassum R 2019-09-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31551469 Genetic architecture of human plasma lipidome and its link to cardiovascular disease. Sterol levels 2,045 European ancestry individuals NA Illumina [~ 9300000] (imputed) 0 sterol measurement http://www.ebi.ac.uk/efo/EFO_0010231 GCST008934 Genome-wide genotyping array 2045 2019-10-25 31551469 Tabassum R 2019-09-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31551469 Genetic architecture of human plasma lipidome and its link to cardiovascular disease. Low density lipoprotein cholesterol levels 2,045 European ancestry individuals NA Illumina [~ 9300000] (imputed) 1 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST008935 Genome-wide genotyping array 2045 2019-10-25 31551469 Tabassum R 2019-09-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31551469 Genetic architecture of human plasma lipidome and its link to cardiovascular disease. High density lipoprotein cholesterol levels 2,045 European ancestry individuals NA Illumina [~ 9300000] (imputed) 3 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST008936 Genome-wide genotyping array 2045 2019-10-25 31551469 Tabassum R 2019-09-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31551469 Genetic architecture of human plasma lipidome and its link to cardiovascular disease. Triglyceride levels 2,045 European ancestry individuals NA Illumina [~ 9300000] (imputed) 2 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST008937 Genome-wide genotyping array 2045 2019-10-25 31551469 Tabassum R 2019-09-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31551469 Genetic architecture of human plasma lipidome and its link to cardiovascular disease. Total cholesterol levels 2,045 European ancestry individuals NA Illumina [~ 9300000] (imputed) 1 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST008938 Genome-wide genotyping array 2045 2019-10-23 31553412 Legge SE 2019-09-25 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/31553412 Association of Genetic Liability to Psychotic Experiences With Neuropsychotic Disorders and Traits. Psychotic experience 6,123 European ancestry cases, 121,379 European ancestry controls NA Affymetrix [> 7500000] (imputed) 2 psychotic symptoms http://www.ebi.ac.uk/efo/EFO_0005940 GCST008895 Genome-wide genotyping array 127502 2019-10-23 31553412 Legge SE 2019-09-25 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/31553412 Association of Genetic Liability to Psychotic Experiences With Neuropsychotic Disorders and Traits. Psychotic experience (multiple occurrences) 3,337 European ancestry cases, 121,379 European ancestry controls NA Affymetrix [> 7500000] (imputed) 0 psychotic symptoms http://www.ebi.ac.uk/efo/EFO_0005940 GCST008897 Genome-wide genotyping array 124716 2019-10-23 31553412 Legge SE 2019-09-25 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/31553412 Association of Genetic Liability to Psychotic Experiences With Neuropsychotic Disorders and Traits. Psychotic experience (distressing) 2,143 European ancestry cases, 121,379 European ancestry controls NA Affymetrix [> 7500000] (imputed) 2 psychotic symptoms http://www.ebi.ac.uk/efo/EFO_0005940 GCST008896 Genome-wide genotyping array 123522 2019-10-04 30679032 Brazel DM 2018-12-06 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30679032 Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use. Smoking behaviour (age at first cigarette) up to 2,705 African ancestry individuals NA Illumina [~ 250000] (imputed) 0 time to first cigarette measurement http://www.ebi.ac.uk/efo/EFO_0010126 GCST008807 Exome genotyping array [Exome array] 2705 2019-10-04 30679032 Brazel DM 2018-12-06 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30679032 Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use. Smoking behaviour (cigarettes smoked per day) up to 2,685 African ancestry individuals NA Illumina [~ 250000] (imputed) 1 cigarettes per day measurement http://www.ebi.ac.uk/efo/EFO_0006525 GCST008804 Exome genotyping array [Exome array] 2685 2019-10-04 30679032 Brazel DM 2018-12-06 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30679032 Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use. Alcohol consumption (drinks per week) up to 7,594 African ancestry individuals NA Illumina [~ 250000] (imputed) 0 alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0007878 GCST008805 Exome genotyping array [Exome array] 7594 2019-10-04 30679032 Brazel DM 2018-12-06 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30679032 Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use. Smoking behaviour (cigarette pack-years) up to 2,658 African ancestry individuals NA Illumina [~ 250000] (imputed) 0 tobacco smoke exposure measurement http://www.ebi.ac.uk/efo/EFO_0009115 GCST008808 Exome genotyping array [Exome array] 2658 2019-10-04 30679032 Brazel DM 2018-12-06 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30679032 Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use. Smoking initiation (ever regular vs never regular) up to 8,974 African ancestry individuals NA Illumina [~ 250000] (imputed) 0 smoking initiation http://www.ebi.ac.uk/efo/EFO_0005670 GCST008806 Exome genotyping array [Exome array] 8974 2019-10-04 30679032 Brazel DM 2018-12-06 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30679032 Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use. Smoking behaviour (age at first cigarette) up to 146,117 European ancestry control NA Illumina [~ 250000] (imputed) 3 time to first cigarette measurement http://www.ebi.ac.uk/efo/EFO_0010126 GCST008802 Exome genotyping array [Exome array] 146117 2019-10-04 30679032 Brazel DM 2018-12-06 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30679032 Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use. Smoking behaviour (cigarettes smoked per day) up to 153,918 European ancestry individuals NA Illumina [~ 250000] (imputed) 12 cigarettes per day measurement http://www.ebi.ac.uk/efo/EFO_0006525 GCST008809 Exome genotyping array [Exome array] 153918 2019-10-04 30679032 Brazel DM 2018-12-06 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30679032 Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use. Smoking behaviour (cigarette pack-years) up to 150,993 European ancestry individuals NA Illumina [~ 250000] (imputed) 17 tobacco smoke exposure measurement http://www.ebi.ac.uk/efo/EFO_0009115 GCST008803 Exome genotyping array [Exome array] 150993 2019-10-04 30679032 Brazel DM 2018-12-06 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30679032 Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use. Smoking initiation (ever regular vs never regular) up to 433,216 European ancestry individuals NA Illumina [~ 250000] (imputed) 99 smoking initiation http://www.ebi.ac.uk/efo/EFO_0005670 GCST008810 Exome genotyping array [Exome array] 433216 2019-10-04 30679032 Brazel DM 2018-12-06 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30679032 Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use. Alcohol consumption (drinks per week) up to 357,854 European ancestry individuals NA Illumina [~ 250000] (imputed) 51 alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0007878 GCST008811 Exome genotyping array [Exome array] 357854 2019-10-21 31174203 Liyanage UE 2019-06-07 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31174203 Combined analysis of keratinocyte cancers identifies novel genome-wide loci. Keratinocyte cancer (MTAG) at least 18,538 European ancestry cases, at least 340,302 European ancestry controls NA Affymetrix [7600000] (imputed) 88 keratinocyte carcinoma http://www.ebi.ac.uk/efo/EFO_0010176 GCST008870 Genome-wide genotyping array 358840 2019-10-21 31174203 Liyanage UE 2019-06-07 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31174203 Combined analysis of keratinocyte cancers identifies novel genome-wide loci. Basal cell carcinoma 31,787 European ancestry cases, 619,351 European ancestry controls NA Affymetrix, Illumina [up to 9061544] (imputed) 76 basal cell carcinoma http://www.ebi.ac.uk/efo/EFO_0004193 GCST008871 Genome-wide genotyping array 651138 2019-10-21 31174203 Liyanage UE 2019-06-07 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31174203 Combined analysis of keratinocyte cancers identifies novel genome-wide loci. Squamous cell carcinoma 9,674 European ancestry cases, 625,657 European ancestry controls NA Affymetrix, Illumina [up to 9061544] (imputed) 21 squamous cell carcinoma http://www.ebi.ac.uk/efo/EFO_0000707 GCST008872 Genome-wide genotyping array 635331 2019-11-13 31473137 Moreno-Grau S 2019-08-13 Alzheimers Dement www.ncbi.nlm.nih.gov/pubmed/31473137 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project. Alzheimer's disease 4,120 Spanish ancestry cases, 11,999 cases, 3,289 Spanish ancestry controls, 9,236 controls 1,943 Spanish ancestry cases, 3,016 Spanish ancestry controls Affymetrix [up to 7700000] (imputed) 6 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST009019 Genome-wide genotyping array 28644 2019-11-13 31473137 Moreno-Grau S 2019-08-13 Alzheimers Dement www.ncbi.nlm.nih.gov/pubmed/31473137 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project. Alzheimer's disease 4,120 Spanish ancestry cases, 17,008 cases, 3,289 Spanish ancestry controls, 37,154 controls 1,943 Spanish ancestry cases, 8,572 cases, 3,016 Spanish ancestry controls, 11,312 controls Affymetrix [up to 7055881] (imputed) 20 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST009021 Genome-wide genotyping array 61571 2019-11-13 31473137 Moreno-Grau S 2019-08-13 Alzheimers Dement www.ncbi.nlm.nih.gov/pubmed/31473137 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project. Alzheimer's disease 4,120 European ancestry cases, 3,289 European ancestry controls NA Affymetrix [7700000] (imputed) 1 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST009020 Genome-wide genotyping array 7409 2019-11-13 31473137 Moreno-Grau S 2019-08-13 Alzheimers Dement www.ncbi.nlm.nih.gov/pubmed/31473137 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project. Alzheimer’s disease and/or vascular dementia (clinical subgroup VaD+) 1,168 Spanish ancestry cases, 3,289 Spanish ancestry controls NA Affymetrix [~ 7700000] (imputed) 1 Alzheimer's disease, vascular dementia http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0004718 GCST009025 Genome-wide genotyping array 4457 2019-11-13 31473137 Moreno-Grau S 2019-08-13 Alzheimers Dement www.ncbi.nlm.nih.gov/pubmed/31473137 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project. Alzheimer’s disease (clinical subgroup AD+) 3,797 Spanish ancestry cases, 3,289 Spanish ancestry controls NA Affymetrix [~ 7700000] (imputed) 1 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST009022 Genome-wide genotyping array 7086 2019-11-13 31473137 Moreno-Grau S 2019-08-13 Alzheimers Dement www.ncbi.nlm.nih.gov/pubmed/31473137 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project. Alzheimer’s disease (clinical subgroup AD++) 2,611 Spanish ancestry cases, 3,289 Spanish ancestry controls NA Affymetrix [~ 7700000] (imputed) 1 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST009023 Genome-wide genotyping array 5900 2019-11-13 31473137 Moreno-Grau S 2019-08-13 Alzheimers Dement www.ncbi.nlm.nih.gov/pubmed/31473137 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project. Alzheimer’s disease (clinical subgroup AD+++) 1,854 Spanish ancestry cases, 3,289 Spanish ancestry controls NA Affymetrix [~ 7700000] (imputed) 1 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST009024 Genome-wide genotyping array 5143 2019-11-13 31473137 Moreno-Grau S 2019-08-13 Alzheimers Dement www.ncbi.nlm.nih.gov/pubmed/31473137 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project. Alzheimer’s disease and/or vascular dementia (clinical subgroup VaD++) 373 Spanish ancestry cases, 3,289 Spanish ancestry controls NA Affymetrix [~ 7700000] (imputed) 1 Alzheimer's disease, vascular dementia http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0004718 GCST009026 Genome-wide genotyping array 3662 2019-10-02 28330615 Rhinn H 2017-03-18 Cell Syst www.ncbi.nlm.nih.gov/pubmed/28330615 Differential Aging Analysis in Human Cerebral Cortex Identifies Variants in TMEM106B and GRN that Regulate Aging Phenotypes. Differential aging in older adults (frontal cortex) 413 individuals 497 individuals NR [468129] 1 brain measurement, aging http://www.ebi.ac.uk/efo/EFO_0004464, http://purl.obolibrary.org/obo/GO_0007568 GCST008795 Genome-wide genotyping array 413 2019-10-02 28330615 Rhinn H 2017-03-18 Cell Syst www.ncbi.nlm.nih.gov/pubmed/28330615 Differential Aging Analysis in Human Cerebral Cortex Identifies Variants in TMEM106B and GRN that Regulate Aging Phenotypes. Differential aging in younger adults (frontal cortex) 303 individuals NA NR [468129] 0 brain measurement, aging http://www.ebi.ac.uk/efo/EFO_0004464, http://purl.obolibrary.org/obo/GO_0007568 GCST008796 Genome-wide genotyping array 303 2019-10-02 28330615 Rhinn H 2017-03-18 Cell Syst www.ncbi.nlm.nih.gov/pubmed/28330615 Differential Aging Analysis in Human Cerebral Cortex Identifies Variants in TMEM106B and GRN that Regulate Aging Phenotypes. Differential aging (cerebellum) 716 individuals 497 individuals NR [468129] 0 brain measurement, aging http://www.ebi.ac.uk/efo/EFO_0004464, http://purl.obolibrary.org/obo/GO_0007568 GCST008797 Genome-wide genotyping array 716 2019-10-02 28330615 Rhinn H 2017-03-18 Cell Syst www.ncbi.nlm.nih.gov/pubmed/28330615 Differential Aging Analysis in Human Cerebral Cortex Identifies Variants in TMEM106B and GRN that Regulate Aging Phenotypes. Differential aging in older adults (cerebellum) 413 individuals 497 individuals NR [468129] 0 brain measurement, aging http://www.ebi.ac.uk/efo/EFO_0004464, http://purl.obolibrary.org/obo/GO_0007568 GCST008798 Genome-wide genotyping array 413 2019-10-02 28330615 Rhinn H 2017-03-18 Cell Syst www.ncbi.nlm.nih.gov/pubmed/28330615 Differential Aging Analysis in Human Cerebral Cortex Identifies Variants in TMEM106B and GRN that Regulate Aging Phenotypes. Differential aging (frontal cortex) 303 individuals NA NR [468129] 0 brain measurement, aging http://www.ebi.ac.uk/efo/EFO_0004464, http://purl.obolibrary.org/obo/GO_0007568 GCST008799 Genome-wide genotyping array 303 2019-10-02 28330615 Rhinn H 2017-03-18 Cell Syst www.ncbi.nlm.nih.gov/pubmed/28330615 Differential Aging Analysis in Human Cerebral Cortex Identifies Variants in TMEM106B and GRN that Regulate Aging Phenotypes. Differential aging (frontal cortex) 716 individuals 497 individuals NR [468129] 1 brain measurement, aging http://www.ebi.ac.uk/efo/EFO_0004464, http://purl.obolibrary.org/obo/GO_0007568 GCST008800 Genome-wide genotyping array 716 2019-10-17 31560688 Geidenstam N 2019-09-27 PLoS One www.ncbi.nlm.nih.gov/pubmed/31560688 Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain. Triacylglycerol 56:6 levels 1,937 individuals NA Affymetrix, Illumina [up to 22000000] (imputed) 10 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST008862 Genome-wide genotyping array 1937 2019-10-17 31560688 Geidenstam N 2019-09-27 PLoS One www.ncbi.nlm.nih.gov/pubmed/31560688 Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain. Malate levels 1,937 individuals NA Affymetrix, Illumina [up to 22000000] (imputed) 4 malate measurement http://www.ebi.ac.uk/efo/EFO_0010508 GCST008863 Genome-wide genotyping array 1937 2019-10-17 31560688 Geidenstam N 2019-09-27 PLoS One www.ncbi.nlm.nih.gov/pubmed/31560688 Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain. Niacinamide levels 1,937 individuals NA Affymetrix, Illumina [up to 22000000] (imputed) 2 niacinamide measurement http://www.ebi.ac.uk/efo/EFO_0010511 GCST008864 Genome-wide genotyping array 1937 2019-10-17 31560688 Geidenstam N 2019-09-27 PLoS One www.ncbi.nlm.nih.gov/pubmed/31560688 Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain. Sphingomyelin 24:0 levels 1,937 individuals NA Affymetrix, Illumina [up to 22000000] (imputed) 6 sphingomyelin measurement http://www.ebi.ac.uk/efo/EFO_0010118 GCST008865 Genome-wide genotyping array 1937 2019-10-21 31560688 Geidenstam N 2019-09-27 PLoS One www.ncbi.nlm.nih.gov/pubmed/31560688 Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain. Uridine levels 1,937 individuals NA Affymetrix, Illumina [up to 22000000] (imputed) 2 uridine measurement http://www.ebi.ac.uk/efo/EFO_0010546 GCST008894 Genome-wide genotyping array 1937 2019-10-17 31560688 Geidenstam N 2019-09-27 PLoS One www.ncbi.nlm.nih.gov/pubmed/31560688 Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain. Triacylglycerol 56:2 levels 1,937 individuals NA Affymetrix, Illumina [up to 22000000] (imputed) 4 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST008866 Genome-wide genotyping array 1937 2019-10-17 31560688 Geidenstam N 2019-09-27 PLoS One www.ncbi.nlm.nih.gov/pubmed/31560688 Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain. Tyrosine levels 1,937 individuals NA Affymetrix, Illumina [up to 22000000] (imputed) 7 tyrosine measurement http://www.ebi.ac.uk/efo/EFO_0005058 GCST008867 Genome-wide genotyping array 1937 2019-10-17 31560688 Geidenstam N 2019-09-27 PLoS One www.ncbi.nlm.nih.gov/pubmed/31560688 Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain. Xanthine levels 1,937 individuals NA Affymetrix, Illumina [up to 22000000] (imputed) 2 xanthine measurement http://www.ebi.ac.uk/efo/EFO_0010548 GCST008868 Genome-wide genotyping array 1937 2019-10-17 31560688 Geidenstam N 2019-09-27 PLoS One www.ncbi.nlm.nih.gov/pubmed/31560688 Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain. Metabolite risk score for predicting weight gain 1,937 individuals NA Affymetrix, Illumina [up to 22000000] (imputed) 7 metabolite measurement, body weight gain http://www.ebi.ac.uk/efo/EFO_0004725, http://www.ebi.ac.uk/efo/EFO_0004566 GCST008869 Genome-wide genotyping array 1937 2019-10-10 31497858 Dumitrescu L 2019-09-01 Brain www.ncbi.nlm.nih.gov/pubmed/31497858 Sex differences in the genetic predictors of Alzheimer's pathology. Neuritic plaque 2,701 European ancestry men, 3,275 European ancestry women NA Affymetrix, Illumina [NR] (imputed) 11 neuritic plaque measurement http://www.ebi.ac.uk/efo/EFO_0006798 GCST008829 Genome-wide genotyping array 5976 2019-10-09 31497858 Dumitrescu L 2019-09-01 Brain www.ncbi.nlm.nih.gov/pubmed/31497858 Sex differences in the genetic predictors of Alzheimer's pathology. Neurofibrillary tangles 2,701 European ancestry men NA Affymetrix, Illumina [NR] (imputed) 13 neurofibrillary tangles measurement http://www.ebi.ac.uk/efo/EFO_0006797 GCST008821 Genome-wide genotyping array 2701 2019-10-10 31497858 Dumitrescu L 2019-09-01 Brain www.ncbi.nlm.nih.gov/pubmed/31497858 Sex differences in the genetic predictors of Alzheimer's pathology. Neurofibrillary tangles 3,275 European ancestry women NA Affymetrix, Illumina [NR] (imputed) 19 neurofibrillary tangles measurement http://www.ebi.ac.uk/efo/EFO_0006797 GCST008830 Genome-wide genotyping array 3275 2019-10-09 31497858 Dumitrescu L 2019-09-01 Brain www.ncbi.nlm.nih.gov/pubmed/31497858 Sex differences in the genetic predictors of Alzheimer's pathology. Neuritic plaque 2,701 European ancestry men NA Affymetrix, Illumina [NR] (imputed) 9 neuritic plaque measurement http://www.ebi.ac.uk/efo/EFO_0006798 GCST008822 Genome-wide genotyping array 2701 2018-12-10 29227965 Pilling LC 2017-12-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29227965 Human longevity: 25 genetic loci associated in 389,166 UK biobank participants. Parental longevity (combined parental attained age, Martingale residuals) 389,166 British ancestry individuals NA Affymetrix [11535925] (imputed) 38 parental longevity http://www.ebi.ac.uk/efo/EFO_0007796 GCST006697 Genome-wide genotyping array 389166 2018-12-10 29227965 Pilling LC 2017-12-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29227965 Human longevity: 25 genetic loci associated in 389,166 UK biobank participants. Parental longevity (both parents in top 10%) 7,182 cases, 79,767 controls NA Affymetrix [11535925] (imputed) 9 parental longevity http://www.ebi.ac.uk/efo/EFO_0007796 GCST006698 Genome-wide genotyping array 86949 2018-12-10 29227965 Pilling LC 2017-12-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29227965 Human longevity: 25 genetic loci associated in 389,166 UK biobank participants. Parental longevity (mother's age at death) 246,941 British ancestry individuals NA Affymetrix [11535925] (imputed) 3 parental longevity http://www.ebi.ac.uk/efo/EFO_0007796 GCST006699 Genome-wide genotyping array 246941 2018-12-10 29227965 Pilling LC 2017-12-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29227965 Human longevity: 25 genetic loci associated in 389,166 UK biobank participants. Parental longevity (mother's attained age) 412,937 British ancestry individuals NA Affymetrix [11535925] (imputed) 8 parental longevity http://www.ebi.ac.uk/efo/EFO_0007796 GCST006696 Genome-wide genotyping array 412937 2018-12-10 29227965 Pilling LC 2017-12-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29227965 Human longevity: 25 genetic loci associated in 389,166 UK biobank participants. Parental longevity (father's age at death) 317,652 British ancestry individuals NA Affymetrix [11535925] (imputed) 5 parental longevity http://www.ebi.ac.uk/efo/EFO_0007796 GCST006700 Genome-wide genotyping array 317652 2018-12-10 29227965 Pilling LC 2017-12-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29227965 Human longevity: 25 genetic loci associated in 389,166 UK biobank participants. Parental longevity (father's attained age) 415,311 British ancestry individuals NA Affymetrix [11535925] (imputed) 17 parental longevity http://www.ebi.ac.uk/efo/EFO_0007796 GCST006701 Genome-wide genotyping array 415311 2018-12-10 29227965 Pilling LC 2017-12-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29227965 Human longevity: 25 genetic loci associated in 389,166 UK biobank participants. Parental longevity (combined parental age at death) 208,118 British ancestry individuals NA Affymetrix [11535925] (imputed) 8 parental longevity http://www.ebi.ac.uk/efo/EFO_0007796 GCST006702 Genome-wide genotyping array 208118 2019-02-06 29160301 Fabbri C 2017-11-21 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/29160301 New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation. Response to SSRI (symptom improvement) 1,828 European ancestry individuals 1,472 European ancestry individuals Affymetrix, Illumina [7062950] (imputed) 0 response to selective serotonin reuptake inhibitor http://www.ebi.ac.uk/efo/EFO_0005658 GCST007042 Genome-wide genotyping array 1828 2019-02-08 29160301 Fabbri C 2017-11-21 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/29160301 New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation. Response to antidepressants (symptom improvement) 2,145 European ancestry individuals NA Affymetrix, Illumina [7062950] (imputed) 18 response to antidepressant http://purl.obolibrary.org/obo/GO_0036276 GCST007059 Genome-wide genotyping array 2145 2019-02-08 29160301 Fabbri C 2017-11-21 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/29160301 New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation. Response to SSRI (symptom remission) 1,828 European ancestry individuals NA Affymetrix, Illumina [7062950] (imputed) 8 response to selective serotonin reuptake inhibitor http://www.ebi.ac.uk/efo/EFO_0005658 GCST007060 Genome-wide genotyping array 1828 2019-02-08 29160301 Fabbri C 2017-11-21 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/29160301 New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation. Response to antidepressants (symptom remission) 2,145 European ancestry individuals NA Affymetrix, Illumina [7062950] (imputed) 11 response to antidepressant http://purl.obolibrary.org/obo/GO_0036276 GCST007061 Genome-wide genotyping array 2145 2019-10-01 31511532 Teumer A 2019-09-11 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31511532 Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. Urinary albumin-to-creatinine ratio 547,361 European ancestry individuals NA Affymetrix, Illumina [8603712] (imputed) 63 urinary albumin to creatinine ratio http://www.ebi.ac.uk/efo/EFO_0007778 GCST008794 Genome-wide genotyping array 547361 2019-10-01 31511532 Teumer A 2019-09-11 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31511532 Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. Urinary albumin-to-creatinine ratio 6,795 African American individuals NA Affymetrix, Illumina [at least 8034757] (imputed) 1 urinary albumin to creatinine ratio http://www.ebi.ac.uk/efo/EFO_0007778 GCST008793 Genome-wide genotyping array 6795 2019-10-01 31511532 Teumer A 2019-09-11 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31511532 Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. Urinary albumin-to-creatinine ratio in diabetes 51,541 European, African American, East Asian, South Asian or Hispanic ancestry individuals NA Affymetrix, Illumina [8034757] (imputed) 8 urinary albumin to creatinine ratio http://www.ebi.ac.uk/efo/EFO_0007778 GCST008792 Genome-wide genotyping array 51541 2019-10-01 31511532 Teumer A 2019-09-11 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31511532 Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. Microalbuminuria 51,861 European, African American, East Asian, South Asian or Hispanic ancestry cases, 297,093 European, African American, East Asian, South Asian or Hispanic ancestry controls NA Affymetrix, Illumina [8326000] (imputed) 29 Moderate albuminuria http://purl.obolibrary.org/obo/HP_0012594 GCST008791 Genome-wide genotyping array 348954 2019-10-01 31511532 Teumer A 2019-09-11 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31511532 Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. Urinary albumin-to-creatinine ratio 547,361 European ancestry individuals, 6,795 African American individuals, 6,324 East Asian ancestry individuals, 2,335 South Asian ancestry individuals, 1,442 Hispanic individuals NA Affymetrix, Illumina [8034757] (imputed) 59 urinary albumin to creatinine ratio http://www.ebi.ac.uk/efo/EFO_0007778 GCST008790 Genome-wide genotyping array 564257 2019-09-23 31501611 Karlsson T 2019-09-09 Nat Med www.ncbi.nlm.nih.gov/pubmed/31501611 Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease. Predicted visceral adipose tissue 163,984 British ancestry men NA Affymetrix [10549349] (imputed) 2 visceral adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004765 GCST008743 Genome-wide genotyping array 163984 2019-09-23 31501611 Karlsson T 2019-09-09 Nat Med www.ncbi.nlm.nih.gov/pubmed/31501611 Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease. Predicted visceral adipose tissue 161,168 British ancestry women NA Affymetrix [10549349] (imputed) 2 visceral adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004765 GCST008742 Genome-wide genotyping array 161168 2019-09-23 31501611 Karlsson T 2019-09-09 Nat Med www.ncbi.nlm.nih.gov/pubmed/31501611 Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease. Predicted visceral adipose tissue 325,153 British ancestry individuals NA Affymetrix [10549349] (imputed) 205 visceral adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004765 GCST008744 Genome-wide genotyping array 325153 2020-02-25 31628463 Chai JF 2019-10-19 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31628463 Associations with metabolites in Chinese suggest new metabolic roles in Alzheimer's and Parkinson's diseases. Metabolite levels 1,954 Chinese ancestry individuals NA Illumina [~ 47000000] (imputed) 134 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST009698 Genome-wide genotyping array 1954 2019-10-28 30576415 Gilly A 2019-08-01 Bioinformatics www.ncbi.nlm.nih.gov/pubmed/30576415 Very low-depth whole-genome sequencing in complex trait association studies. Blood pressure 1,225 Mylopotamos (founder/genetic isolate) individuals NA Illumina [14948665] (imputed) 2 blood pressure http://www.ebi.ac.uk/efo/EFO_0004325 GCST008964 Genome-wide genotyping array 1225 2019-10-28 30576415 Gilly A 2019-08-01 Bioinformatics www.ncbi.nlm.nih.gov/pubmed/30576415 Very low-depth whole-genome sequencing in complex trait association studies. Glucose homeostasis traits 1,225 Mylopotamos (founder/genetic isolate) individuals NA Illumina [14948665] (imputed) 6 diabetes mellitus biomarker http://www.ebi.ac.uk/efo/EFO_0006842 GCST008963 Genome-wide genotyping array 1225 2019-10-28 30576415 Gilly A 2019-08-01 Bioinformatics www.ncbi.nlm.nih.gov/pubmed/30576415 Very low-depth whole-genome sequencing in complex trait association studies. Hematology traits 1,225 Mylopotamos (founder/genetic isolate) individuals NA Illumina [14948665] (imputed) 15 hematological measurement http://www.ebi.ac.uk/efo/EFO_0004503 GCST008962 Genome-wide genotyping array 1225 2019-10-28 30576415 Gilly A 2019-08-01 Bioinformatics www.ncbi.nlm.nih.gov/pubmed/30576415 Very low-depth whole-genome sequencing in complex trait association studies. Hormone measurements 1,225 Mylopotamos (founder/genetic isolate) individuals NA Illumina [14948665] (imputed) 7 hormone measurement http://www.ebi.ac.uk/efo/EFO_0004730 GCST008957 Genome-wide genotyping array 1225 2019-10-28 30576415 Gilly A 2019-08-01 Bioinformatics www.ncbi.nlm.nih.gov/pubmed/30576415 Very low-depth whole-genome sequencing in complex trait association studies. C-reactive protein levels 1,225 Mylopotamos (founder/genetic isolate) individuals NA Illumina [14948665] (imputed) 0 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST008961 Genome-wide genotyping array 1225 2019-10-28 30576415 Gilly A 2019-08-01 Bioinformatics www.ncbi.nlm.nih.gov/pubmed/30576415 Very low-depth whole-genome sequencing in complex trait association studies. Iron status biomarkers 1,225 Mylopotamos (founder/genetic isolate) individuals NA Illumina [14948665] (imputed) 1 iron biomarker measurement http://www.ebi.ac.uk/efo/EFO_0004461 GCST008960 Genome-wide genotyping array 1225 2019-10-28 30576415 Gilly A 2019-08-01 Bioinformatics www.ncbi.nlm.nih.gov/pubmed/30576415 Very low-depth whole-genome sequencing in complex trait association studies. Lipid traits 1,225 Mylopotamos (founder/genetic isolate) individuals NA Illumina [14948665] (imputed) 14 lipid measurement http://www.ebi.ac.uk/efo/EFO_0004529 GCST008959 Genome-wide genotyping array 1225 2019-10-28 30576415 Gilly A 2019-08-01 Bioinformatics www.ncbi.nlm.nih.gov/pubmed/30576415 Very low-depth whole-genome sequencing in complex trait association studies. Liver disease biomarker 1,225 Mylopotamos (founder/genetic isolate) individuals NA Illumina [14948665] (imputed) 2 liver disease biomarker http://www.ebi.ac.uk/efo/EFO_0006845 GCST008965 Genome-wide genotyping array 1225 2019-10-28 30576415 Gilly A 2019-08-01 Bioinformatics www.ncbi.nlm.nih.gov/pubmed/30576415 Very low-depth whole-genome sequencing in complex trait association studies. Anthropometric traits 1,225 Mylopotamos (founder/genetic isolate) individuals NA Illumina [14948665] (imputed) 5 anthropometric measurement http://www.ebi.ac.uk/efo/EFO_0004302 GCST008958 Genome-wide genotyping array 1225 2019-11-18 31607149 Ramirez J 2019-10-14 Circ Arrhythm Electrophysiol www.ncbi.nlm.nih.gov/pubmed/31607149 Cardiovascular Predictive Value and Genetic Basis of Ventricular Repolarization Dynamics. T wave morphology restitution during exercise (MTAG) 51,574 European ancestry individuals NA NR [~ 9000000] (imputed) 8 T wave morphology measurement http://www.ebi.ac.uk/efo/EFO_0008398 GCST009068 Genome-wide genotyping array 51574 2019-11-11 31607149 Ramirez J 2019-10-14 Circ Arrhythm Electrophysiol www.ncbi.nlm.nih.gov/pubmed/31607149 Cardiovascular Predictive Value and Genetic Basis of Ventricular Repolarization Dynamics. T wave morphology restitution during exercise 51,574 European ancestry individuals NA NR [~ 9000000] (imputed) 7 T wave morphology measurement http://www.ebi.ac.uk/efo/EFO_0008398 GCST009016 Genome-wide genotyping array 51574 2019-11-18 31607149 Ramirez J 2019-10-14 Circ Arrhythm Electrophysiol www.ncbi.nlm.nih.gov/pubmed/31607149 Cardiovascular Predictive Value and Genetic Basis of Ventricular Repolarization Dynamics. T wave morphology restitution during recovery from exercise 51,574 European ancestry individuals NA NR [~ 9000000] (imputed) 8 T wave morphology measurement http://www.ebi.ac.uk/efo/EFO_0008398 GCST009069 Genome-wide genotyping array 51574 2019-11-11 31607149 Ramirez J 2019-10-14 Circ Arrhythm Electrophysiol www.ncbi.nlm.nih.gov/pubmed/31607149 Cardiovascular Predictive Value and Genetic Basis of Ventricular Repolarization Dynamics. T wave morphology restitution during recovery from exercise (MTAG) 51,574 European ancestry individuals NA NR [~ 9000000] (imputed) 8 T wave morphology measurement http://www.ebi.ac.uk/efo/EFO_0008398 GCST009017 Genome-wide genotyping array 51574 2019-07-16 30924126 Brackman DJ 2019-03-28 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/30924126 Genome-wide Association and Functional Studies Reveal Novel Pharmacological Mechanisms for Allopurinol. Response to allopurinol in gout (change in serum uric acid levels) 2,647 European ancestry cases, 303 East Asian cases, 115 African American cases, 114 Latino cases 355 European ancestry cases Affymetrix, Illumina [NR] (imputed) 1 response to allopurinol, uric acid measurement http://www.ebi.ac.uk/efo/EFO_0006337, http://www.ebi.ac.uk/efo/EFO_0004761 GCST008148 Genome-wide genotyping array 3179 2019-07-16 30924126 Brackman DJ 2019-03-28 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/30924126 Genome-wide Association and Functional Studies Reveal Novel Pharmacological Mechanisms for Allopurinol. Response to allopurinol in gout (change in serum uric acid levels) 2,647 European ancestry cases, 303 East Asian cases, 115 African American cases, 114 Latino cases 318 European ancestry cases, 502 European ancestry cases Affymetrix, Illumina [NR] (imputed) 1 response to allopurinol, uric acid measurement http://www.ebi.ac.uk/efo/EFO_0006337, http://www.ebi.ac.uk/efo/EFO_0004761 GCST008147 Genome-wide genotyping array 3179 2019-11-19 31626034 Thomsen H 2019-10-11 Melanoma Res www.ncbi.nlm.nih.gov/pubmed/31626034 Genome-wide study on uveal melanoma patients finds association to DNA repair gene TDP1. Uveal melanoma 590 European ancestry cases, 5,199 European ancestry controls NA Illumina [10258281] (imputed) 10 Uveal Melanoma http://www.ebi.ac.uk/efo/EFO_1000616 GCST009071 Genome-wide genotyping array 5789 2019-11-19 31626034 Thomsen H 2019-10-11 Melanoma Res www.ncbi.nlm.nih.gov/pubmed/31626034 Genome-wide study on uveal melanoma patients finds association to DNA repair gene TDP1. Uveal melanoma with any chromosomal aberration 417 European ancestry cases, 5,199 European ancestry controls NA Illumina [10258281] (imputed) 5 Uveal Melanoma http://www.ebi.ac.uk/efo/EFO_1000616 GCST009079 Genome-wide genotyping array 5616 2019-11-19 31626034 Thomsen H 2019-10-11 Melanoma Res www.ncbi.nlm.nih.gov/pubmed/31626034 Genome-wide study on uveal melanoma patients finds association to DNA repair gene TDP1. Choroidal melanoma 438 European ancestry cases, 5,199 European ancestry controls NA Illumina [10258281] (imputed) 6 choroidal melanoma http://www.ebi.ac.uk/efo/EFO_0009093 GCST009078 Genome-wide genotyping array 5637 2019-11-19 31626034 Thomsen H 2019-10-11 Melanoma Res www.ncbi.nlm.nih.gov/pubmed/31626034 Genome-wide study on uveal melanoma patients finds association to DNA repair gene TDP1. Uveal melanoma with chromosome 3 loss 253 European ancestry cases, 5,199 European ancestry controls NA Illumina [10258281] (imputed) 3 Uveal Melanoma http://www.ebi.ac.uk/efo/EFO_1000616 GCST009077 Genome-wide genotyping array 5452 2019-11-19 31626034 Thomsen H 2019-10-11 Melanoma Res www.ncbi.nlm.nih.gov/pubmed/31626034 Genome-wide study on uveal melanoma patients finds association to DNA repair gene TDP1. Uveal melanoma with epithelioid cells 285 European ancestry cases, 5,199 European ancestry controls NA Illumina [10258281] (imputed) 4 Epithelioid Cell Uveal Melanoma http://www.ebi.ac.uk/efo/EFO_1000244 GCST009076 Genome-wide genotyping array 5484 2019-11-19 31626034 Thomsen H 2019-10-11 Melanoma Res www.ncbi.nlm.nih.gov/pubmed/31626034 Genome-wide study on uveal melanoma patients finds association to DNA repair gene TDP1. Presence of epithelioid cells in uveal melanoma 285 European ancestry cases, 286 European ancestry controls NA Illumina [10258281] (imputed) 4 Epithelioid Cell Uveal Melanoma http://www.ebi.ac.uk/efo/EFO_1000244 GCST009075 Genome-wide genotyping array 571 2019-11-19 31626034 Thomsen H 2019-10-11 Melanoma Res www.ncbi.nlm.nih.gov/pubmed/31626034 Genome-wide study on uveal melanoma patients finds association to DNA repair gene TDP1. Uveal melanoma (TNM stage 1 or 2) 330 European ancestry cases, 5,199 European ancestry controls NA Illumina [10258281] (imputed) 4 Uveal Melanoma http://www.ebi.ac.uk/efo/EFO_1000616 GCST009074 Genome-wide genotyping array 5529 2019-11-19 31626034 Thomsen H 2019-10-11 Melanoma Res www.ncbi.nlm.nih.gov/pubmed/31626034 Genome-wide study on uveal melanoma patients finds association to DNA repair gene TDP1. Uveal melanoma (TNM stage 3 or 4) 255 European ancestry cases, 5,199 European ancestry controls NA Illumina [10258281] (imputed) 3 Uveal Melanoma http://www.ebi.ac.uk/efo/EFO_1000616 GCST009073 Genome-wide genotyping array 5454 2019-11-19 31626034 Thomsen H 2019-10-11 Melanoma Res www.ncbi.nlm.nih.gov/pubmed/31626034 Genome-wide study on uveal melanoma patients finds association to DNA repair gene TDP1. Disease severity in uveal melanoma (TNM stage 3 or 4 vs TNM stage 1 or 2) 330 European ancestry stage 3 or 4 cases, 255 European ancestry stage 1 or 2 cases NA Illumina [10258281] (imputed) 5 uveal melanoma disease severity http://www.ebi.ac.uk/efo/EFO_0010244 GCST009072 Genome-wide genotyping array 595 2019-12-18 31620175 Kornilov SA 2019-09-18 Front Genet www.ncbi.nlm.nih.gov/pubmed/31620175 Genome-Wide Homozygosity Mapping Reveals Genes Associated With Cognitive Ability in Children From Saudi Arabia. General cognitive ability 354 Saudi Arabian ancestry children NA Illumina [285340] 0 intelligence http://www.ebi.ac.uk/efo/EFO_0004337 GCST009320 Genome-wide genotyping array 354 2019-12-18 31620175 Kornilov SA 2019-09-18 Front Genet www.ncbi.nlm.nih.gov/pubmed/31620175 Genome-Wide Homozygosity Mapping Reveals Genes Associated With Cognitive Ability in Children From Saudi Arabia. Verbal cognitive ability 354 Saudi Arabian ancestry children NA Illumina [285340] 1 cognitive function measurement, language measurement http://www.ebi.ac.uk/efo/EFO_0008354, http://www.ebi.ac.uk/efo/EFO_0007797 GCST009321 Genome-wide genotyping array 354 2019-12-18 31620175 Kornilov SA 2019-09-18 Front Genet www.ncbi.nlm.nih.gov/pubmed/31620175 Genome-Wide Homozygosity Mapping Reveals Genes Associated With Cognitive Ability in Children From Saudi Arabia. Numerical cognitive ability 354 Saudi Arabian ancestry children NA Illumina [285340] 6 cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0008354 GCST009322 Genome-wide genotyping array 354 2019-12-18 31620175 Kornilov SA 2019-09-18 Front Genet www.ncbi.nlm.nih.gov/pubmed/31620175 Genome-Wide Homozygosity Mapping Reveals Genes Associated With Cognitive Ability in Children From Saudi Arabia. Figural/spatial cognitive ability 354 Saudi Arabian ancestry children NA Illumina [285340] 3 cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0008354 GCST009323 Genome-wide genotyping array 354 2019-11-18 31624269 Terao C 2019-10-17 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31624269 GWAS of mosaic loss of chromosome Y highlights genetic effects on blood cell differentiation. Mosaic loss of chromosome Y (Y chromosome dosage) 95,380 Japanese men NA Illumina [9591901] (imputed) 50 mosaic loss of chromosome Y measurement http://www.ebi.ac.uk/efo/EFO_0007783 GCST009066 Genome-wide genotyping array 95380 2019-11-18 31624269 Terao C 2019-10-17 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31624269 GWAS of mosaic loss of chromosome Y highlights genetic effects on blood cell differentiation. Mosaic loss of chromosome Y (Y chromosome dosage) 205,011 men NA NR [NR] 36 mosaic loss of chromosome Y measurement http://www.ebi.ac.uk/efo/EFO_0007783 GCST009067 Genome-wide genotyping array 205011 2019-12-02 31301374 Noguchi E 2019-07-10 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/31301374 HLA-DQ and RBFOX1 as susceptibility genes for an outbreak of hydrolyzed wheat allergy. Hydrolysed wheat protein allergy 452 Japanese ancestry cases, 2,700 Japaneses ancestry controls 45 Japanese ancestry cases, 326 Japaneses ancestry controls Illumina [6575663] (imputed) 2 wheat allergic reaction http://www.ebi.ac.uk/efo/EFO_1001243 GCST009143 Genome-wide genotyping array 3152 2021-05-26 31610627 Lee YS 2019-09-26 Genomics Inform www.ncbi.nlm.nih.gov/pubmed/31610627 In silico approach to calculate the transcript capacity. Body fat percentage 8,842 individuals NA Affymetrix [308003] 0 body fat percentage http://www.ebi.ac.uk/efo/EFO_0007800 GCST011736 Genome-wide genotyping array 8842 2019-07-30 31295674 Condreay LD 2019-07-05 Respir Med www.ncbi.nlm.nih.gov/pubmed/31295674 No genetic associations with mepolizumab efficacy in COPD with peripheral blood eosinophilia. Exacerbation frequency in mepolizumab-treated chronic obstructive pulmonary disease 504 European ancestry individuals, 73 Asian ancestry individuals, 18 Native American individuals, 5 African American individuals, 10 individuals NA Affymetrix [10000000] (imputed) 0 respiratory symptom measurement, response to mepolizumab http://www.ebi.ac.uk/efo/EFO_0007939, http://www.ebi.ac.uk/efo/EFO_0008459 GCST008269 Genome-wide genotyping array 610 2019-07-30 31295674 Condreay LD 2019-07-05 Respir Med www.ncbi.nlm.nih.gov/pubmed/31295674 No genetic associations with mepolizumab efficacy in COPD with peripheral blood eosinophilia. Frequency of exacerbations requiring hospitalisation in mepolizumab-treated chronic obstructive pulmonary disease 504 European ancestry individuals, 73 Asian ancestry individuals, 18 Native American individuals, 5 African American individuals, 10 individuals NA Affymetrix [10000000] (imputed) 0 respiratory symptom measurement, response to mepolizumab http://www.ebi.ac.uk/efo/EFO_0007939, http://www.ebi.ac.uk/efo/EFO_0008459 GCST008268 Genome-wide genotyping array 610 2019-10-25 31619474 Zhu Z 2019-10-17 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/31619474 Shared Genetics of Asthma and Mental Health Disorders: A Large-Scale Genome-Wide Cross-Trait Analysis. Asthma 46,802 European ancestry cases, 347,481 European ancestry controls 23,948 European and unknown ancestry cases, 118,538 European and unknown ancestry controls Affymetrix [8274727] (imputed) 130 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST008916 Genome-wide genotyping array 394283 2019-10-25 31619474 Zhu Z 2019-10-17 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/31619474 Shared Genetics of Asthma and Mental Health Disorders: A Large-Scale Genome-Wide Cross-Trait Analysis. Asthma (childhood onset) 9,676 European ancestry cases, 347,481 European ancestry controls NA Affymetrix [8274727] (imputed) 2 childhood onset asthma http://www.ebi.ac.uk/efo/EFO_0004591 GCST008917 Genome-wide genotyping array 357157 2019-10-25 31619474 Zhu Z 2019-10-17 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/31619474 Shared Genetics of Asthma and Mental Health Disorders: A Large-Scale Genome-Wide Cross-Trait Analysis. Asthma (adult onset) 22,296 European ancestry cases, 347,481 European ancestry controls NA Affymetrix [8274727] (imputed) 0 adult onset asthma http://www.ebi.ac.uk/efo/EFO_1002011 GCST008918 Genome-wide genotyping array 369777 2019-10-25 31619474 Zhu Z 2019-10-17 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/31619474 Shared Genetics of Asthma and Mental Health Disorders: A Large-Scale Genome-Wide Cross-Trait Analysis. Asthma and attention deficit hyperactivity disorder 46,802 European ancestry asthma cases, 19,099 European ancestry attention deficit hyperactivity disorder cases, 381,675 European ancestry controls NA Affymetrix [up to 8274727] (imputed) 7 attention deficit hyperactivity disorder, asthma http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0000270 GCST008919 Genome-wide genotyping array 447576 2019-10-25 31619474 Zhu Z 2019-10-17 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/31619474 Shared Genetics of Asthma and Mental Health Disorders: A Large-Scale Genome-Wide Cross-Trait Analysis. Asthma and anxiety disorder 46,802 European ancestry asthma cases, 5,710 European ancestry anxiety disorder cases, 359,081 European ancestry controls NA Affymetrix [up to 8274727] (imputed) 1 anxiety disorder, asthma http://www.ebi.ac.uk/efo/EFO_0006788, http://www.ebi.ac.uk/efo/EFO_0000270 GCST008920 Genome-wide genotyping array 411593 2019-10-25 31619474 Zhu Z 2019-10-17 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/31619474 Shared Genetics of Asthma and Mental Health Disorders: A Large-Scale Genome-Wide Cross-Trait Analysis. Asthma and major depressive disorder 46,802 European ancestry asthma cases, 59,851 European ancestry major depressive disorder cases, 460,635 European ancestry controls NA Affymetrix [up to 13554551] (imputed) 10 unipolar depression, asthma http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000270 GCST008921 Genome-wide genotyping array 567288 2019-08-13 31209380 Demontis D 2019-06-17 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/31209380 Genome-wide association study implicates CHRNA2 in cannabis use disorder. Mental disorder 35,006 Danish ancestry cases, 16,366 Danish ancestry controls NA Illumina [8969939] (imputed) 0 attention deficit hyperactivity disorder, unipolar depression, schizophrenia, autism spectrum disorder, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0003756, http://www.ebi.ac.uk/efo/EFO_0000289 GCST008417 Genome-wide genotyping array 51372 2019-08-13 31209380 Demontis D 2019-06-17 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/31209380 Genome-wide association study implicates CHRNA2 in cannabis use disorder. Psychiatric disorder without cannabis use disorder 32,716 Danish ancestry cases, 16,269 Danish ancestry controls NA Illumina [8969939] (imputed) 0 attention deficit hyperactivity disorder, unipolar depression, schizophrenia, autism spectrum disorder, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0003756, http://www.ebi.ac.uk/efo/EFO_0000289 GCST008416 Genome-wide genotyping array 48985 2019-08-13 31209380 Demontis D 2019-06-17 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/31209380 Genome-wide association study implicates CHRNA2 in cannabis use disorder. Cannabis use disorder vs schizophrenia 2,387 Danish ancestry cannabis use disorder cases, 1,789 Danish ancestry schizophrenia cases NA Illumina [8969939] (imputed) 0 schizophrenia, cannabis dependence, substance abuse http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0007191, http://purl.obolibrary.org/obo/MONDO_0002491 GCST008415 Genome-wide genotyping array 4176 2019-08-13 31209380 Demontis D 2019-06-17 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/31209380 Genome-wide association study implicates CHRNA2 in cannabis use disorder. Cannabis use disorder 2,387 Danish ancestry cases, 48,985 Danish ancestry controls 5,501 Icelandic ancestry cases, 301,041 Icelandic ancestry controls Illumina [8969939] (imputed) 1 cannabis dependence, substance abuse http://www.ebi.ac.uk/efo/EFO_0007191, http://purl.obolibrary.org/obo/MONDO_0002491 GCST008414 Genome-wide genotyping array 51372 2020-05-29 32231244 Xie J 2020-03-30 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32231244 The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis. Membranous nephropathy 2,150 European ancestry cases, 5,829 European ancestry controls, 1,612 East Asian ancestry cases, 1,970 East Asian ancestry controls 826 Chinese ancestry cases, 1,239 Chinese ancestry controls Illumina [~ 7000000] (imputed) 4 membranous glomerulonephritis http://www.ebi.ac.uk/efo/EFO_0004254 GCST010004 Genome-wide genotyping array 11561 2020-05-29 32231244 Xie J 2020-03-30 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32231244 The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis. Membranous nephropathy 2,150 European ancestry cases, 5,829 European ancestry controls NA Illumina [~ 7000000] (imputed) 3 membranous glomerulonephritis http://www.ebi.ac.uk/efo/EFO_0004254 GCST010005 Genome-wide genotyping array 7979 2020-05-29 32231244 Xie J 2020-03-30 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32231244 The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis. Membranous nephropathy 1,612 East Asian ancestry cases, 1,970 East Asian ancestry controls NA Illumina [~ 7000000] (imputed) 4 membranous glomerulonephritis http://www.ebi.ac.uk/efo/EFO_0004254 GCST010006 Genome-wide genotyping array 3582 2020-07-21 32238385 Nakayama A 2020-04-01 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/32238385 Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients. Gout 3,053 Japanese ancestry male cases, 4,554 Japanese ancestry male controls NA Illumina [7206774] (imputed) 17 gout http://www.ebi.ac.uk/efo/EFO_0004274 GCST010277 Genome-wide genotyping array 7607 2020-07-21 32238385 Nakayama A 2020-04-01 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/32238385 Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients. Renal underexcretion gout 654 Japanese ancestry male cases, 4,554 Japanese ancestry male controls NA Illumina [7206774] (imputed) 14 gout http://www.ebi.ac.uk/efo/EFO_0004274 GCST010276 Genome-wide genotyping array 5208 2020-07-21 32238385 Nakayama A 2020-04-01 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/32238385 Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients. Renal overload gout 486 Japanese ancestry male cases, 4,554 Japanese ancestry male controls NA Illumina [7206774] (imputed) 5 gout http://www.ebi.ac.uk/efo/EFO_0004274 GCST010275 Genome-wide genotyping array 5040 2020-07-21 32238385 Nakayama A 2020-04-01 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/32238385 Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients. Gout (combined type) 905 Japanese ancestry male cases, 4,554 Japanese ancestry male controls NA Illumina [7206774] (imputed) 9 gout http://www.ebi.ac.uk/efo/EFO_0004274 GCST010274 Genome-wide genotyping array 5459 2020-07-21 32238385 Nakayama A 2020-04-01 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/32238385 Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients. Gout (normal type) 92 Japanese ancestry male cases, 4,554 Japanese ancestry male controls NA Illumina [7206774] (imputed) 11 gout http://www.ebi.ac.uk/efo/EFO_0004274 GCST010273 Genome-wide genotyping array 4646 2020-07-21 32227373 Osazuwa-Peters OL 2020-03-29 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/32227373 Identifying blood pressure loci whose effects are modulated by multiple lifestyle exposures. Systolic blood pressure 6,254 European ancestry individuals NA NR [~ 24000000] (imputed) 1 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST010259 Genome-wide genotyping array 6254 2020-07-21 32227373 Osazuwa-Peters OL 2020-03-29 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/32227373 Identifying blood pressure loci whose effects are modulated by multiple lifestyle exposures. Diastolic blood pressure 6,253 European ancestry individuals NA NR [~ 24000000] (imputed) 3 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST010258 Genome-wide genotyping array 6253 2020-07-21 32227373 Osazuwa-Peters OL 2020-03-29 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/32227373 Identifying blood pressure loci whose effects are modulated by multiple lifestyle exposures. Diastolic blood pressure x quantitative lifestyle risk score interaction (1df test) 6,253 European ancestry individuals NA NR [2411113] (imputed) 2 lifestyle measurement, diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0010724, http://www.ebi.ac.uk/efo/EFO_0006336 GCST010257 Genome-wide genotyping array 6253 2020-07-21 32227373 Osazuwa-Peters OL 2020-03-29 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/32227373 Identifying blood pressure loci whose effects are modulated by multiple lifestyle exposures. Diastolic blood pressure x quantitative lifestyle risk score interaction (2df test) 6,253 European ancestry individuals NA NR [2411113] (imputed) 3 lifestyle measurement, diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0010724, http://www.ebi.ac.uk/efo/EFO_0006336 GCST010256 Genome-wide genotyping array 6253 2020-07-21 32227373 Osazuwa-Peters OL 2020-03-29 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/32227373 Identifying blood pressure loci whose effects are modulated by multiple lifestyle exposures. Diastolic blood pressure x dichotomous lifestyle risk score interaction (1df test) 1,924 European ancestry unexposed individuals, 4,330 European ancestry exposed individuals NA NR [2407627] (imputed) 2 lifestyle measurement, diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0010724, http://www.ebi.ac.uk/efo/EFO_0006336 GCST010255 Genome-wide genotyping array 6254 2020-07-21 32227373 Osazuwa-Peters OL 2020-03-29 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/32227373 Identifying blood pressure loci whose effects are modulated by multiple lifestyle exposures. Diastolic blood pressure x dichotomous lifestyle risk score interaction (2df test) 1,924 European ancestry unexposed individuals, 4,330 European ancestry exposed individuals NA NR [2407627] (imputed) 2 lifestyle measurement, diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0010724, http://www.ebi.ac.uk/efo/EFO_0006336 GCST010254 Genome-wide genotyping array 6254 2020-07-21 32227373 Osazuwa-Peters OL 2020-03-29 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/32227373 Identifying blood pressure loci whose effects are modulated by multiple lifestyle exposures. Systolic blood pressure x quantitative lifestyle risk score interaction (1df test) 6,254 European ancestry individuals NA NR [2411114] (imputed) 3 lifestyle measurement, systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0010724, http://www.ebi.ac.uk/efo/EFO_0006335 GCST010253 Genome-wide genotyping array 6254 2020-07-21 32227373 Osazuwa-Peters OL 2020-03-29 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/32227373 Identifying blood pressure loci whose effects are modulated by multiple lifestyle exposures. Systolic blood pressure x quantitative lifestyle risk score interaction (2df test) 6,254 European ancestry individuals NA NR [2411114] (imputed) 4 lifestyle measurement, systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0010724, http://www.ebi.ac.uk/efo/EFO_0006335 GCST010252 Genome-wide genotyping array 6254 2020-07-21 32227373 Osazuwa-Peters OL 2020-03-29 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/32227373 Identifying blood pressure loci whose effects are modulated by multiple lifestyle exposures. Systolic blood pressure x dichotomous lifestyle risk score interaction (1df test) 1,924 European ancestry unexposed individuals, 4,330 European ancestry exposed individuals NA NR [2407629] (imputed) 2 lifestyle measurement, systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0010724, http://www.ebi.ac.uk/efo/EFO_0006335 GCST010251 Genome-wide genotyping array 6254 2020-07-21 32227373 Osazuwa-Peters OL 2020-03-29 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/32227373 Identifying blood pressure loci whose effects are modulated by multiple lifestyle exposures. Systolic blood pressure x dichotomous lifestyle risk score interaction (2df test) 1,924 European ancestry unexposed individuals, 4,330 European ancestry exposed individuals NA NR [2407629] (imputed) 3 lifestyle measurement, systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0010724, http://www.ebi.ac.uk/efo/EFO_0006335 GCST010250 Genome-wide genotyping array 6254 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Eosinophil counts up to 7,526 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 0 eosinophil count http://www.ebi.ac.uk/efo/EFO_0004842 GCST009041 Genome-wide genotyping array, Genome-wide sequencing 7526 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Total cholesterol levels 14,126 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 5 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST009042 Genome-wide genotyping array, Genome-wide sequencing 14126 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. LDL cholesterol levels 14,126 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 5 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST009043 Genome-wide genotyping array, Genome-wide sequencing 14126 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. HDL cholesterol levels 14,126 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 4 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST009044 Genome-wide genotyping array, Genome-wide sequencing 14126 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Triglyceride levels 14,126 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 4 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST009045 Genome-wide genotyping array, Genome-wide sequencing 14126 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Aspartate aminotransferase levels up to 9,004 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 0 aspartate aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004736 GCST009046 Genome-wide genotyping array, Genome-wide sequencing 9004 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Alanine aminotransferase levels 14,126 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 1 serum alanine aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004735 GCST009047 Genome-wide genotyping array, Genome-wide sequencing 14126 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Serum albumin levels 14,126 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 1 serum albumin measurement http://www.ebi.ac.uk/efo/EFO_0004535 GCST009048 Genome-wide genotyping array, Genome-wide sequencing 14126 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Serum alkaline phosphatase levels 14,126 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 2 alkaline phosphatase measurement http://www.ebi.ac.uk/efo/EFO_0004533 GCST009049 Genome-wide genotyping array, Genome-wide sequencing 14126 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Gamma glutamyl transferase levels up to 9,004 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 1 serum gamma-glutamyl transferase measurement http://www.ebi.ac.uk/efo/EFO_0004532 GCST009050 Genome-wide genotyping array, Genome-wide sequencing 9004 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Bilirubin levels 14,126 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 2 bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004570 GCST009051 Genome-wide genotyping array, Genome-wide sequencing 14126 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Diastolic blood pressure 14,126 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 0 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST009052 Genome-wide genotyping array, Genome-wide sequencing 14126 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Systolic blood pressure 14,126 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 0 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST009053 Genome-wide genotyping array, Genome-wide sequencing 14126 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Hemoglobin A1c levels up to 7,526 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 2 hemoglobin A1 measurement http://www.ebi.ac.uk/efo/EFO_0007629 GCST009054 Genome-wide genotyping array, Genome-wide sequencing 7526 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Height 14,126 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 1 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST009055 Genome-wide genotyping array, Genome-wide sequencing 14126 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Weight 14,126 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 0 body weight http://www.ebi.ac.uk/efo/EFO_0004338 GCST009056 Genome-wide genotyping array, Genome-wide sequencing 14126 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Body mass index 14,126 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 2 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST009057 Genome-wide genotyping array, Genome-wide sequencing 14126 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Hip circumference 14,126 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 1 hip circumference http://www.ebi.ac.uk/efo/EFO_0005093 GCST009059 Genome-wide genotyping array, Genome-wide sequencing 14126 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Red blood cell count up to 7,526 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 1 erythrocyte count http://www.ebi.ac.uk/efo/EFO_0004305 GCST009062 Genome-wide genotyping array, Genome-wide sequencing 7526 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Waist circumference 14,126 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 0 waist circumference http://www.ebi.ac.uk/efo/EFO_0004342 GCST009058 Genome-wide genotyping array, Genome-wide sequencing 14126 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Waist-hip ratio 14,126 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 0 waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0004343 GCST009060 Genome-wide genotyping array, Genome-wide sequencing 14126 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. White blood cell count up to 7,526 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 2 leukocyte count http://www.ebi.ac.uk/efo/EFO_0004308 GCST009061 Genome-wide genotyping array, Genome-wide sequencing 7526 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Mean corpuscular volume up to 7,526 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 1 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST009065 Genome-wide genotyping array, Genome-wide sequencing 7526 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Mean corpuscular hemoglobin up to 7,526 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 1 mean corpuscular hemoglobin http://www.ebi.ac.uk/efo/EFO_0004527 GCST009063 Genome-wide genotyping array, Genome-wide sequencing 7526 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Mean corpuscular hemoglobin concentration up to 7,526 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 1 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST009064 Genome-wide genotyping array, Genome-wide sequencing 7526 2019-11-18 31420334 Lindstrom S 2019-08-16 Blood www.ncbi.nlm.nih.gov/pubmed/31420334 Genomic and Transcriptomic Association Studies Identify 16 Novel Susceptibility Loci for Venous Thromboembolism. Venous thromboembolism 29,435 European ancestry cases, 157,769 European ancestry controls NA Affymetrix, Illumina [12923718] (imputed) 109 venous thromboembolism http://www.ebi.ac.uk/efo/EFO_0004286 GCST009029 Genome-wide genotyping array, Exome-wide sequencing 187204 2019-11-18 31420334 Lindstrom S 2019-08-16 Blood www.ncbi.nlm.nih.gov/pubmed/31420334 Genomic and Transcriptomic Association Studies Identify 16 Novel Susceptibility Loci for Venous Thromboembolism. Venous thromboembolism 799 African American cases, 14,353 African American controls NA Affymetrix, Illumina [12923718] (imputed) 12 venous thromboembolism http://www.ebi.ac.uk/efo/EFO_0004286 GCST009031 Genome-wide genotyping array 15152 2019-11-18 31420334 Lindstrom S 2019-08-16 Blood www.ncbi.nlm.nih.gov/pubmed/31420334 Genomic and Transcriptomic Association Studies Identify 16 Novel Susceptibility Loci for Venous Thromboembolism. Venous thromboembolism 29,435 European ancestry cases, 799 African American cases, 157,769 European ancestry controls, 14,353 African American controls NA Affymetrix, Illumina [12923718] (imputed) 34 venous thromboembolism http://www.ebi.ac.uk/efo/EFO_0004286 GCST009030 Genome-wide genotyping array, Exome-wide sequencing 202356 2019-10-16 31562340 Akiyama M 2019-09-27 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31562340 Characterizing rare and low-frequency height-associated variants in the Japanese population. Height 159,095 Japanese ancestry individuals 32,692 Japanese ancestry individuals Illumina [27896057] (imputed) 608 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST008839 Genome-wide genotyping array 159095 2019-03-13 30487263 Pollack S 2018-11-28 Diabetes www.ncbi.nlm.nih.gov/pubmed/30487263 Multiethnic Genome-wide Association Study of Diabetic Retinopathy using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control. Diabetic retinopathy (all NPDR and PDR) 1,079 European ancestry cases, 1,970 European ancestry controls, 911 African American cases, 941 African American controls 7,178 East Asian ancestry cases, 6,525 East Asian ancestry controls, 214 South East Asian ancestry cases, 557 South East Asian ancestry controls, 315 South Asian ancestry cases, 669 South Asian ancestry controls, 8,205 European ancestry cases, 7,713 European ancestry controls, 1,470 Hispanic cases, 1,240 Hispanic controls Affymetrix, Illumina [NR] (imputed) 19 diabetic retinopathy http://www.ebi.ac.uk/efo/EFO_0003770 GCST007292 Genome-wide genotyping array 4901 2019-03-13 30487263 Pollack S 2018-11-28 Diabetes www.ncbi.nlm.nih.gov/pubmed/30487263 Multiethnic Genome-wide Association Study of Diabetic Retinopathy using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control. Proliferative diabetic retinopathy (vs NPDR and no DR) 398 European ancestry cases, 2,848 European ancestry controls, 1,097 African American cases, 1,514 African American controls 918 East Asian ancestry cases, 1,167 East Asian ancestry controls, 2,038 European ancestry cases, 6,783 European ancestry controls, 232 Hispanic cases, 2,194 Hispanic controls Affymetrix, Illumina [NR] (imputed) 19 proliferative diabetic retinopathy http://www.ebi.ac.uk/efo/EFO_0009322 GCST007289 Genome-wide genotyping array 5857 2019-03-13 30487263 Pollack S 2018-11-28 Diabetes www.ncbi.nlm.nih.gov/pubmed/30487263 Multiethnic Genome-wide Association Study of Diabetic Retinopathy using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control. Diabetic retinopathy (moderate NPDR and PDR) 644 European ancestry cases, 1,970 European ancestry controls, 768 African American cases, 941 African American controls 2,388 East Asian ancestry cases, 6,219 East Asian ancestry controls, 1,658 European ancestry cases, 3,019 European ancestry controls, 1,014 Hispanic cases, 1,240 Hispanic controls Affymetrix, Illumina [NR] (imputed) 20 diabetic retinopathy http://www.ebi.ac.uk/efo/EFO_0003770 GCST007290 Genome-wide genotyping array 4323 2019-03-13 30487263 Pollack S 2018-11-28 Diabetes www.ncbi.nlm.nih.gov/pubmed/30487263 Multiethnic Genome-wide Association Study of Diabetic Retinopathy using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control. Proliferative diabetic retinopathy (vs no DR) 398 European ancestry cases, 1,970 European ancestry controls, 1,097 African American cases, 941 African American controls 1,354 East Asian ancestry cases, 1130 East Asian ancestry controls, 801 European ancestry cases, 2,880 European ancestry controls, 232 Hispanic cases, 1,048 Hispanic controls Affymetrix, Illumina [NR] (imputed) 19 proliferative diabetic retinopathy http://www.ebi.ac.uk/efo/EFO_0009322 GCST007291 Genome-wide genotyping array 4406 2019-12-11 31708768 Liu C 2019-10-25 Front Aging Neurosci www.ncbi.nlm.nih.gov/pubmed/31708768 Genome-Wide Association Studies for Cerebrospinal Fluid Soluble TREM2 in Alzheimer's Disease. Cerebrospinal fluid sTREM-2 levels 224 healthy normal individuals, 72 significant memory concern individuals, 234 early mild cognitive impairment individuals, 277 late mild cognitive impairment individuals, 194 Alzheimer's disease cases NA Illumina [2379855] 203 soluble triggering receptor expressed on myeloid cells 2 measurement http://www.ebi.ac.uk/efo/EFO_0010151 GCST009246 Genome-wide genotyping array 1001 2020-02-18 31779001 Franck M 2019-11-28 Lifestyle Genom www.ncbi.nlm.nih.gov/pubmed/31779001 Prevention of Potential Adverse Metabolic Effects of a Supplementation with Omega-3 Fatty Acids Using a Genetic Score Approach. Impaired insulin sensitivity in response to n-3 PUFA supplementation 32 French Canadian ancestry cases, 106 French Canadian ancestry controls NA Illumina [2668805] 8 insulin sensitivity measurement, response to polyunsaturated fatty acid supplementation http://www.ebi.ac.uk/efo/EFO_0004471, http://www.ebi.ac.uk/efo/EFO_0009131 GCST009642 Genome-wide genotyping array 138 2020-02-14 31776335 Jonsson BA 2019-11-27 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31776335 Brain age prediction using deep learning uncovers associated sequence variants. Brain age (difference between predicted and chronological age) 12,378 British ancestry individuals 4,456 British ancestry individuals Affymetrix [20000000] (imputed) 0 brain age measurement http://www.ebi.ac.uk/efo/EFO_0010602 GCST009611 Genome-wide genotyping array 12378 2020-02-13 31873298 Cortes A 2019-12-23 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31873298 Identifying cross-disease components of genetic risk across hospital data in the UK Biobank. 19,155 disease classifications in UK Biobank (pleiotropy) 320,644 British ancestry individuals NA Affymetrix [654546] 0 complex trait http://www.ebi.ac.uk/efo/EFO_0010578 GCST009606 Genome-wide genotyping array 320644 2020-03-03 29926116 Grarup N 2018-06-20 Diabetologia www.ncbi.nlm.nih.gov/pubmed/29926116 Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population. Type 2 diabetes 317 Greenlandic ancestry cases, 2,631 Greenlandic ancestry controls NA Illumina [115182] 3 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST009732 Targeted genotyping array [Metabochip] 2948 2020-07-21 32239398 Liu L 2020-04-01 Hum Genet www.ncbi.nlm.nih.gov/pubmed/32239398 Two novel pleiotropic loci associated with osteoporosis and abdominal obesity. Femoral neck bone mineral density 10,208 European ancestry individuals, 445 Hispanic individuals, 843 African ancestry individuals, 1,539 East Asian individuals NA Affymetrix, Illumina [12061510] (imputed) 8 femoral neck bone mineral density http://www.ebi.ac.uk/efo/EFO_0007785 GCST010268 Genome-wide genotyping array 13035 2020-07-21 32239398 Liu L 2020-04-01 Hum Genet www.ncbi.nlm.nih.gov/pubmed/32239398 Two novel pleiotropic loci associated with osteoporosis and abdominal obesity. Trunk fat mass adjusted for trunk lean mass 10,208 European ancestry individuals, 445 Hispanic individuals, 843 African ancestry individuals, 1,539 East Asian individuals NA Affymetrix, Illumina [12061510] (imputed) 9 lean mass-adjusted fat body mass http://www.ebi.ac.uk/efo/EFO_0009890 GCST010267 Genome-wide genotyping array 13035 2020-07-21 32239398 Liu L 2020-04-01 Hum Genet www.ncbi.nlm.nih.gov/pubmed/32239398 Two novel pleiotropic loci associated with osteoporosis and abdominal obesity. Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass 10,208 European ancestry individuals, 445 Hispanic individuals, 843 African ancestry individuals, 1,539 East Asian individuals NA Affymetrix, Illumina [12061510] (imputed) 18 lean mass-adjusted fat body mass, femoral neck bone mineral density http://www.ebi.ac.uk/efo/EFO_0009890, http://www.ebi.ac.uk/efo/EFO_0007785 GCST010266 Genome-wide genotyping array 13035 2020-07-21 32222710 Hosgood Iii HD 2020-03-27 Respiration www.ncbi.nlm.nih.gov/pubmed/32222710 PRDM15 Is Associated with Risk of Chronic Obstructive Pulmonary Disease in a Rural Population in Chile. Chronic obstructive pulmonary disease 214 Chilean cases, 193 Chilean controls NA Illumina [455564] (imputed) 5 chronic obstructive pulmonary disease http://www.ebi.ac.uk/efo/EFO_0000341 GCST010249 Genome-wide genotyping array 407 2020-04-17 32131869 Arbeeva L 2020-03-04 J Foot Ankle Res www.ncbi.nlm.nih.gov/pubmed/32131869 Genome-wide meta-analysis identified novel variant associated with hallux valgus in Caucasians. Hallux valgus 609 European ancestry male cases, 1,666 European ancestry male controls NA Affymetrix, Illumina [up to 7729175] (imputed) 17 Hallux valgus http://purl.obolibrary.org/obo/HP_0001822 GCST009846 Genome-wide genotyping array 2275 2020-04-17 32131869 Arbeeva L 2020-03-04 J Foot Ankle Res www.ncbi.nlm.nih.gov/pubmed/32131869 Genome-wide meta-analysis identified novel variant associated with hallux valgus in Caucasians. Hallux valgus 1,705 European ancestry female cases, 1,945 European ancestry female controls NA Affymetrix, Illumina [up to 7729175] (imputed) 14 Hallux valgus http://purl.obolibrary.org/obo/HP_0001822 GCST009849 Genome-wide genotyping array 3650 2020-04-17 32131869 Arbeeva L 2020-03-04 J Foot Ankle Res www.ncbi.nlm.nih.gov/pubmed/32131869 Genome-wide meta-analysis identified novel variant associated with hallux valgus in Caucasians. Hallux valgus 2,314 European ancestry cases, 3,611 European ancestry controls NA Affymetrix, Illumina [up to 7729175] (imputed) 14 Hallux valgus http://purl.obolibrary.org/obo/HP_0001822 GCST009847 Genome-wide genotyping array 5925 2020-06-16 32246137 Meng W 2020-04-03 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/32246137 A genome-wide association study finds genetic variants associated with neck or shoulder pain in UK Biobank. Neck pain or shoulder pain 53,994 European ancestry cases, 149,312 European ancestry controls 5,035 cases, 18,545 controls NR [9304965] (imputed) 4 Shoulder pain, Neck pain http://purl.obolibrary.org/obo/HP_0030834, http://purl.obolibrary.org/obo/HP_0030833 GCST010080 Genome-wide genotyping array 203306 2020-07-21 32239439 Barr PB 2020-04-01 Behav Genet www.ncbi.nlm.nih.gov/pubmed/32239439 A Family-Based Genome Wide Association Study of Externalizing Behaviors. Externalizing behaviour score 7,568 European ancestry individuals, 3,274 African ancestry individuals, 4,270 European and African ancestry individuals NA Affymetrix, Illumina [up to 15537641] (imputed) 5 substance abuse, antisocial behaviour measurement http://purl.obolibrary.org/obo/MONDO_0002491, http://www.ebi.ac.uk/efo/EFO_0007052 GCST010280 Genome-wide genotyping array 15112 2021-03-18 31687947 Kobakhidze N 2019-09-01 Georgian Med News www.ncbi.nlm.nih.gov/pubmed/31687947 NEW GENETIC MARKERS ASSOCIATED WITH SUSCEPTIBILITY TO EXFOLIATION SYNDROME AMONG GEORGIAN POPULATION. Exfoliation syndrome 132 Georgian ancestry cases, 199 Georgian ancestry controls NA Illumina [at least 680000] 0 exfoliation syndrome http://www.ebi.ac.uk/efo/EFO_0004235 GCST011297 Genome-wide genotyping array 331 2019-11-26 31676865 Klarin D 2019-11-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31676865 Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease. Venous thromboembolism 23,151 European ancestry cases, 553,439 European ancestry controls, 2,261 African American cases, 49,400 African American controls, 654 Hispanic cases, 21,214 Hispanic controls 17,672 cases, 167,295 controls Affymetrix [up to 34000000] (imputed) 18 venous thromboembolism http://www.ebi.ac.uk/efo/EFO_0004286 GCST009097 Genome-wide genotyping array 650119 2020-01-29 31694877 Nishida Y 2019-11-06 J Lipid Res www.ncbi.nlm.nih.gov/pubmed/31694877 The interaction between ABCA1 polymorphism and physical activity on the HDL-cholesterol levels in a Japanese population. HDL cholesterol levels 2,231 Japanese ancestry men 2,599 Japanese ancestry men Illumina [7094228] (imputed) 5 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST009528 Genome-wide genotyping array 2231 2020-01-29 31694877 Nishida Y 2019-11-06 J Lipid Res www.ncbi.nlm.nih.gov/pubmed/31694877 The interaction between ABCA1 polymorphism and physical activity on the HDL-cholesterol levels in a Japanese population. HDL cholesterol levels 2,431 Japanese ancestry women 3,109 Japanese ancestry women Illumina [7094228] (imputed) 5 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST009527 Genome-wide genotyping array 2431 2020-03-09 31710517 Allen RJ 2019-11-11 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/31710517 Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis. Idiopathic pulmonary fibrosis 2,668 European ancestry cases, 8,591 European ancestry controls 1,456 European ancestry cases, 11,874 European ancestry controls Affymetrix, Illumina [10790934] (imputed) 17 idiopathic pulmonary fibrosis http://www.ebi.ac.uk/efo/EFO_0000768 GCST009758 Genome-wide genotyping array 11259 2020-02-11 31729369 Howles SA 2019-11-15 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31729369 Genetic variants of calcium and vitamin D metabolism in kidney stone disease. Kidney stones 6,536 British ancestry cases, 388,508 British ancestry controls NA Affymetrix [~ 8400000] (imputed) 15 nephrolithiasis http://www.ebi.ac.uk/efo/EFO_0004253 GCST009599 Genome-wide genotyping array 395044 2020-02-11 31729369 Howles SA 2019-11-15 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31729369 Genetic variants of calcium and vitamin D metabolism in kidney stone disease. Kidney stones 6,536 British ancestry cases, 5,587 Japanese ancestry cases, 388,508 British ancestry controls, 28,870 Japanese ancestry controls NA Affymetrix, Illumina [~ 5000000] (imputed) 20 nephrolithiasis http://www.ebi.ac.uk/efo/EFO_0004253 GCST009598 Genome-wide genotyping array 429501 2019-11-28 31712607 Nudel R 2019-11-11 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31712607 A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population. Hospital contact for infections 21,728 Danish ancestry cases with psychiatric disorders, 6,744 Danish ancestry cases, 24,161 Danish ancestry controls with psychiatric disorders, 12,901 Danish ancestry controls NA Illumina [11600722] (imputed) 30 susceptibility to infectious disease measurement http://www.ebi.ac.uk/efo/EFO_0008422 GCST009130 Genome-wide genotyping array 65534 2020-07-20 32198502 Shin J 2020-03-20 Cereb Cortex www.ncbi.nlm.nih.gov/pubmed/32198502 Global and Regional Development of the Human Cerebral Cortex: Molecular Architecture and Occupational Aptitudes. Cortical surface area (visual PC2) 23,784 European ancestry individuals 19,512 European ancestry individuals, 6,234 individuals Affymetrix, Illumina [NR] (imputed) 30 visual cortical surface area measurement http://www.ebi.ac.uk/efo/EFO_0004771 GCST010225 Genome-wide genotyping array 23784 2020-07-20 32198502 Shin J 2020-03-20 Cereb Cortex www.ncbi.nlm.nih.gov/pubmed/32198502 Global and Regional Development of the Human Cerebral Cortex: Molecular Architecture and Occupational Aptitudes. Cortical thickness (PC1) 23,784 European ancestry individuals 19,512 European ancestry individuals, 6,234 individuals Affymetrix, Illumina [NR] (imputed) 0 cortical thickness http://www.ebi.ac.uk/efo/EFO_0004840 GCST010224 Genome-wide genotyping array 23784 2020-07-20 32198502 Shin J 2020-03-20 Cereb Cortex www.ncbi.nlm.nih.gov/pubmed/32198502 Global and Regional Development of the Human Cerebral Cortex: Molecular Architecture and Occupational Aptitudes. Cortical thickness (PC2) 23,784 European ancestry individuals 19,512 European ancestry individuals, 6,234 individuals Affymetrix, Illumina [NR] (imputed) 0 cortical thickness http://www.ebi.ac.uk/efo/EFO_0004840 GCST010223 Genome-wide genotyping array 23784 2020-07-20 32198502 Shin J 2020-03-20 Cereb Cortex www.ncbi.nlm.nih.gov/pubmed/32198502 Global and Regional Development of the Human Cerebral Cortex: Molecular Architecture and Occupational Aptitudes. Cortical surface area (global PC1) 23,784 European ancestry individuals 19,512 European ancestry individuals, 6,234 individuals Affymetrix, Illumina [NR] (imputed) 15 total cortical area measurement http://www.ebi.ac.uk/efo/EFO_0008381 GCST010226 Genome-wide genotyping array 23784 2020-06-17 32317632 van de Vegte YJ 2020-04-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32317632 Genome-wide association studies and Mendelian randomization analyses for leisure sedentary behaviours. Leisure sedentary behaviour (television watching) 408,815 European ancestry individuals NA Affymetrix [19400418] (imputed) 157 lifestyle measurement http://www.ebi.ac.uk/efo/EFO_0010724 GCST010084 Genome-wide genotyping array 408815 2020-06-17 32317632 van de Vegte YJ 2020-04-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32317632 Genome-wide association studies and Mendelian randomization analyses for leisure sedentary behaviours. Leisure sedentary behaviour (computer use) 408,815 European ancestry individuals NA Affymetrix [19400418] (imputed) 39 lifestyle measurement http://www.ebi.ac.uk/efo/EFO_0010724 GCST010085 Genome-wide genotyping array 408815 2020-06-17 32317632 van de Vegte YJ 2020-04-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32317632 Genome-wide association studies and Mendelian randomization analyses for leisure sedentary behaviours. Driving (hours per day) 408,815 European ancestry individuals NA Affymetrix [19400418] (imputed) 7 lifestyle measurement http://www.ebi.ac.uk/efo/EFO_0010724 GCST010086 Genome-wide genotyping array 408815 2021-05-14 32358372 Ouyang H 2020-05-01 Medicine (Baltimore) www.ncbi.nlm.nih.gov/pubmed/32358372 Constructing gene network for type 1 narcolepsy based on genome-wide association study and differential gene expression analysis (STROBE). Narcolepsy with cataplexy 903 Chinese ancestry cases, 1,982 Chinese ancestry controls NA Affymetrix [237955] (imputed) 6 narcolepsy with cataplexy http://www.ebi.ac.uk/efo/EFO_0000614 GCST011662 Genome-wide genotyping array 2885 2020-07-24 32355309 Cha PC 2020-05-01 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32355309 Genome-wide association study identifies zonisamide responsive gene in Parkinson's disease patients. Levodopa wearing off effect (time symptoms uncontrolled) in Parkinson's disease (response to zonisamide) 67 Japanese ancestry responders, 133 Japanese ancestry poor responders NA Illumina [611492] 4 motor function measurement, response to zonisamide, response to levodopa http://www.ebi.ac.uk/efo/EFO_0010749, http://www.ebi.ac.uk/efo/EFO_0010748, http://www.ebi.ac.uk/efo/EFO_0010747 GCST010322 Genome-wide genotyping array 200 2020-07-24 32355309 Cha PC 2020-05-01 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32355309 Genome-wide association study identifies zonisamide responsive gene in Parkinson's disease patients. Levodopa wearing off effect (motor symptom score change) in Parkinson's disease (response to zonisamide) 67 Japanese ancestry responders, 133 Japanese ancestry poor responders NA Illumina [611492] 1 motor function measurement, response to zonisamide, response to levodopa http://www.ebi.ac.uk/efo/EFO_0010749, http://www.ebi.ac.uk/efo/EFO_0010748, http://www.ebi.ac.uk/efo/EFO_0010747 GCST010323 Genome-wide genotyping array 200 2020-07-27 32341457 Sato Y 2020-04-27 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32341457 Genome-wide association study of semen volume, sperm concentration, testis size, and plasma inhibin B levels. Inhibin B levels 811 Japanese ancestry individuals 721 Japanese ancestry individuals Illumina [3901256] (imputed) 1 Inhibin B measurement http://www.ebi.ac.uk/efo/EFO_0010746 GCST010336 Genome-wide genotyping array 811 2020-07-23 32341457 Sato Y 2020-04-27 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32341457 Genome-wide association study of semen volume, sperm concentration, testis size, and plasma inhibin B levels. Semen volume 811 Japanese ancestry individuals 721 Japanese ancestry individuals Illumina [3901256] (imputed) 0 semen measurement http://www.ebi.ac.uk/efo/EFO_0010745 GCST010310 Genome-wide genotyping array 811 2020-07-23 32341457 Sato Y 2020-04-27 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32341457 Genome-wide association study of semen volume, sperm concentration, testis size, and plasma inhibin B levels. Sperm concentration 811 Japanese ancestry individuals 721 Japanese ancestry individuals Illumina [3901256] (imputed) 0 sperm measurement http://www.ebi.ac.uk/efo/EFO_0010743 GCST010309 Genome-wide genotyping array 811 2020-07-23 32341457 Sato Y 2020-04-27 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32341457 Genome-wide association study of semen volume, sperm concentration, testis size, and plasma inhibin B levels. Testis size 811 Japanese ancestry individuals 721 Japanese ancestry individuals Illumina [3901256] (imputed) 0 testis size http://www.ebi.ac.uk/efo/EFO_0010744 GCST010308 Genome-wide genotyping array 811 2021-02-04 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (RELEASE 5) 29,071 European ancestry cases, 1,559,712 European ancestry controls, 576 Latin American cases, 4,955 Latin American controls, 1,495 East Asian ancestry cases, 15,499 East Asian ancestry controls, 1,688 South Asian ancestry cases, 42,016 South Asian ancestry controls, 2,038 African ancestry cases, 28,066 African ancestry controls, 700 Arab ancestry cases, 13,360 Arab ancestry controls, 1,022 Admixed American ancestry cases, 5,330 Admixed American ancestry controls NA Affymetrix, Illumina [24600933] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST011071 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 1705528 2021-02-04 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (RELEASE 5) 31,562 European ancestry cases, 1,026,848 European ancestry controls, 2,619 Latin American cases, 15,491 Latin American controls, 1,495 East Asian ancestry cases, 15,499 East Asian ancestry controls, 1,379 South Asian ancestry cases, 32,785 South Asian ancestry controls, 2,338 African ancestry cases, 23,485 African ancestry controls, 700 Arab ancestry cases, 13,360 Arab ancestry controls, 1,022 Admixed American ancestry cases, 5,330 Admixed American ancestry controls NA Affymetrix, Illumina [24600933] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST011072 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 1173913 2021-02-04 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (RELEASE 5) 38,984 European ancestry cases, 1,644,784 European ancestry controls NA Affymetrix, Illumina [24600933] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST011073 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 1683768 2021-02-04 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (RELEASE 5) 32,494 European ancestry cases, 1,316,207 European ancestry controls NA Affymetrix, Illumina [24600933] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST011074 Genome-wide genotyping array, Exome-wide sequencing, Genome-wide sequencing 1348701 2020-07-13 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (very severe respiratory confirmed vs population) RELEASE 3 435 European ancestry cases, 327,858 European ancestry controls, 101 Latin American cases, 1,533 Latin American controls NA Affymetrix, Illumina [9309252] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST010198 Genome-wide genotyping array, Exome-wide sequencing, Genome-wide sequencing 329927 2020-07-13 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (hospitalized vs not hospitalized) RELEASE 3 928 European ancestry cases, 2,028 European ancestry controls NA Affymetrix, Illumina [12029424] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST010199 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 2956 2020-07-13 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (hospitalized vs population) RELEASE 3 2,961 European ancestry hospitalized cases, 868,602 European ancestry controls, 176 Latin American hospitalized cases, 1,533 Latin American controls, 62 South Asian ancestry hospitalized cases, 27,353 South Asian ancestry controls NA Affymetrix, Illumina [15392647] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST010200 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 900687 2020-07-13 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (covid vs lab/self reported negative) RELEASE 3 3,289 Europen ancestry cases, 36,125 European ancestry controls, 114 South Asian ancestry cases, 256 South Asian ancestry controls, 63 African ancestry cases, 125 African ancestry controls, 57 Central/South Asian ancestry cases, 128 Central/South Asian ancestry controls NA Affymetrix, Illumina [22039729] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST010201 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 40157 2020-07-13 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (RELEASE 3) 6,089 European ancestry cases, 1,015,145 European ancestry controls, 197 Arab ancestry cases, 13,698 Arab ancestry cases, 176 Latin American cases, 1,533 Latin American controls, 114 South Asian ancestry cases, 27,301 South Asian ancestry controls, 63 African ancestry cases, 6,573 African ancestry controls, 57 Central/South Asian ancestry cases, 8,819 Central/South Asian ancestry controls NA Affymetrix, Illumina [24600933] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST010202 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 1079765 2020-07-13 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (predicted from self-reported symptoms vs predicted or self-reported non-covid) RELEASE 3 1,865 European ancestry cases, 29,174 European ancestry controls NA Affymetrix, Illumina [24600933] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST010203 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 31039 2021-02-04 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (very severe respiratory confirmed vs population) RELEASE 5 5,101 European ancestry cases, 1,383,241 European ancestry controls NA Affymetrix, Illumina [9309252] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST011075 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 1388342 2021-02-04 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (very severe respiratory confirmed vs population) RELEASE 5 4,606 European ancestry cases, 702,801 European ancestry controls, 539 Latin American cases, 1,149 Latin American controls, 133 African American cases, 2,610 African American controls, 304 East Asian ancestry cases, 2,450 East Asian ancestry controls NA Affymetrix, Illumina [9309252] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST011076 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 714592 2021-02-04 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (very severe respiratory confirmed vs population) RELEASE 5 4,792 European ancestry cases, 1,054,664 European ancestry controls, 641 Latin American cases, 96,479 Latin American controls, 133 African American cases, 2,610 African American controls, 304 East Asian ancestry cases, 2,450 East Asian ancestry controls NA Affymetrix, Illumina [9309252] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST011077 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 1162073 2021-02-04 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (very severe respiratory confirmed vs population) RELEASE 5 4,792 European ancestry cases, 1,054,664 European ancestry controls NA Affymetrix, Illumina [9309252] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST011078 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 1059456 2021-02-04 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (hospitalized vs not hospitalized) RELEASE 5 3,159 European ancestry cases, 7,206 European ancestry controls NA Affymetrix, Illumina [12029424] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST011079 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 10365 2021-02-04 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (hospitalized vs not hospitalized) RELEASE 5 4,829 European ancestry cases, 11,816 European ancestry controls NA Affymetrix, Illumina [12029424] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST011080 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 16645 2021-02-04 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (hospitalized vs population) RELEASE 5 9,986 European ancestry cases, 1,877,672 European ancestry controls NA Affymetrix, Illumina [15392647] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST011081 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 1887658 2021-02-04 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (hospitalized vs population) RELEASE 5 8,316 European ancestry cases, 1,549,095 European ancestry controls, 257 Latin American cases, 94,912 Latin American controls, 115 South Asian ancestry cases, 34,049 South Asian ancestry controls, 60 Arab ancestry cases, 13,360 Arab ancestry controls, 653 African ancestry cases, 4,355 African ancestry controls, 1,414 East Asian ancestry cases, 15,499 East Asian ancestry controls, 948 Admixed American ancestry cases, 5,404 Admixed American ancestry controls NA Affymetrix, Illumina [15392647] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST011082 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 1728437 2021-02-04 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (hospitalized vs population) RELEASE 5 8,316 European ancestry cases, 1,549,095 European ancestry controls NA Affymetrix, Illumina [15392647] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST011083 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 1557411 2021-02-04 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (hospitalized vs population) RELEASE 5 9,373 European ancestry cases, 1,197,256 European ancestry controls, 117 Latin American cases, 585 Latin American controls, 186 South Asian ancestry cases, 43,280 South Asian ancestry controls, 60 Arab ancestry cases, 13,360 Arab ancestry controls, 790 African ancestry cases, 20,582 African ancestry controls, 1,414 East Asian ancestry cases, 15,499 East Asian ancestry controls, 948 Admixed American ancestry cases, 5,404 Admixed American ancestry controls NA Affymetrix, Illumina [15392647] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST011084 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 1308854 2020-11-27 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (RELEASE 4) 14,134 European ancestry cases, 1,284,876 European ancestry controls, 1,332 Latin American cases, 6,592 Latin American controls, 66 Central Asian ancestry cases, 8,487 Central Asian ancestry controls, 108 East Asian ancestry cases, 6,500 East Asian ancestry controls, 114 South Asian ancestry cases, 27,301 South Asian ancestry controls, 1,511 African ancestry cases, 23,431 African ancestry controls, 700 Arab ancestry cases, 13,360 Arab ancestry controls NA Affymetrix, Illumina [24600933] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST010780 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 1388512 2020-11-27 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (very severe respiratory confirmed vs population) RELEASE 4 3,886 European ancestry cases, 622,265 European ancestry controls, 450 Latin American cases, 1,637 Latin American controls NA Affymetrix, Illumina [9309252] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST010783 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 628238 2020-11-27 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (hospitalized covid vs not hospitalized) RELEASE 4 1,776 European ancestry cases, 6,443 European ancestry controls, 62 South Asian ancestry cases, 41 South Asian ancestry controls, 415 African ancestry cases, 962 African ancestry controls, 60 Arab ancestry cases, 640 Arab ancestry controls, 117 Hispanic cases, 392 Hispanic controls NA Affymetrix, Illumina [12029424] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST010782 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 10908 2020-11-27 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (predicted covid from self-reported symptoms vs predicted or self-reported non-covid) RELEASE 4 3,204 European ancestry cases, 35,728 European ancestry controls NA Affymetrix, Illumina [24600933] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST010781 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 38932 2020-05-14 32157176 Buchwald J 2020-03-10 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32157176 Genome-wide association meta-analysis of nicotine metabolism and cigarette consumption measures in smokers of European descent. Nicotine metabolite ratio in current smokers 5,185 European ancestry individuals NA Illumina [9622178] (imputed) 2 nicotine metabolite ratio http://www.ebi.ac.uk/efo/EFO_0007794 GCST009971 Genome-wide genotyping array 5185 2020-05-14 32157176 Buchwald J 2020-03-10 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32157176 Genome-wide association meta-analysis of nicotine metabolism and cigarette consumption measures in smokers of European descent. Cotinine and 3'-hydroxycotinine levels in current smokers 5,185 European ancestry individuals NA Illumina [9622178] (imputed) 3 cotinine measurement, trans-3-hydroxycotinine measurement http://www.ebi.ac.uk/efo/EFO_0007813, http://www.ebi.ac.uk/efo/EFO_0010707 GCST009970 Genome-wide genotyping array 5185 2020-05-14 32157176 Buchwald J 2020-03-10 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32157176 Genome-wide association meta-analysis of nicotine metabolism and cigarette consumption measures in smokers of European descent. Cotinine levels in current smokers 5,185 European ancestry individuals, 3,700 individuals NA Illumina [9795096] (imputed) 0 cotinine measurement http://www.ebi.ac.uk/efo/EFO_0007813 GCST009969 Genome-wide genotyping array 8885 2020-05-14 32157176 Buchwald J 2020-03-10 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32157176 Genome-wide association meta-analysis of nicotine metabolism and cigarette consumption measures in smokers of European descent. Smoking behaviour (cigarettes smoked per day) 4,772 European ancestry individuals NA Illumina [9622178] (imputed) 2 cigarettes per day measurement http://www.ebi.ac.uk/efo/EFO_0006525 GCST009968 Genome-wide genotyping array 4772 2020-05-14 32157176 Buchwald J 2020-03-10 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32157176 Genome-wide association meta-analysis of nicotine metabolism and cigarette consumption measures in smokers of European descent. Smoking behaviour (cigarette pack-years) 4,676 European ancestry individuals NA Illumina [9622178] (imputed) 2 pack-years measurement http://www.ebi.ac.uk/efo/EFO_0006526 GCST009967 Genome-wide genotyping array 4676 2020-05-14 32157176 Buchwald J 2020-03-10 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32157176 Genome-wide association meta-analysis of nicotine metabolism and cigarette consumption measures in smokers of European descent. Smoking intensity (cotinine levels/cigarettes per day) 4,772 European ancestry individuals NA Illumina [9622178] (imputed) 2 cotinine measurement, cigarettes per day measurement http://www.ebi.ac.uk/efo/EFO_0007813, http://www.ebi.ac.uk/efo/EFO_0006525 GCST009966 Genome-wide genotyping array 4772 2020-05-14 32157176 Buchwald J 2020-03-10 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32157176 Genome-wide association meta-analysis of nicotine metabolism and cigarette consumption measures in smokers of European descent. Cotinine levels in current smokers 5,185 European ancestry individuals NA Illumina [9622178] (imputed) 3 cotinine measurement http://www.ebi.ac.uk/efo/EFO_0007813 GCST009965 Genome-wide genotyping array 5185 2020-11-27 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (hospitalized vs population) RELEASE 4 6,406 European ancestry hospitalized cases, 902,088 European ancestry controls, 873 Latin American hospitalized cases, 2,222 Latin American controls, 62 South Asian ancestry hospitalized cases, 27,353 South Asian ancestry controls, 60 Arab ancestry hospitalized cases, 13,360 Arab ancestry controls, 415 African ancestry hospitalized cases, 10,281 African ancestry controls, 69 East Asian ancestry hospitalized cases, 6,500 East Asian ancestry controls NA Affymetrix, Illumina [15392647] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST010779 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 969689 2020-11-27 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (covid vs lab/self reported negative) RELEASE 4 8,818 Europen ancestry cases, 101,806 European ancestry controls, 114 South Asian ancestry cases, 256 South Asian ancestry controls, 63 African ancestry cases, 125 African ancestry controls, 66 Central/South Asian ancestry cases, 350 Central/South Asian ancestry controls, 576 Latin American cases, 3,601 Latin American controls NA Affymetrix, Illumina [22039729] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST010778 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 115775 2021-02-04 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (hospitalized vs not hospitalized) RELEASE 5 4,829 European ancestry cases, 11,816 European ancestry controls, 186 South Asian ancestry cases, 1,494 South Asian ancestry controls, 486 African ancestry cases, 1,081 African ancestry controls, 60 Arab ancestry cases, 640 Arab ancestry controls, 117 Hispanic cases, 392 Hispanic controls, 95 Admixed American ancestry cases, 75 Admixed American ancestry controls NA Affymetrix, Illumina [12029424] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST011086 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 21271 2021-02-04 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (hospitalized vs not hospitalized) RELEASE 5 3,159 European ancestry cases, 7,206 European ancestry controls, 115 South Asian ancestry cases, 1,264 South Asian ancestry controls, 415 African ancestry cases, 962 African ancestry controls, 60 Arab ancestry cases, 640 Arab ancestry controls, 117 Hispanic cases, 392 Hispanic controls, 95 Admixed American ancestry cases, 74 Admixed American ancestry controls NA Affymetrix, Illumina [12029424] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST011085 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 14499 2020-11-27 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (hospitalized vs population) RELEASE 4 6,406 European ancestry cases, 902,088 European ancestry controls NA Affymetrix, Illumina [15392647] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST010777 Genome-wide genotyping array, Exome-wide sequencing, Genome-wide sequencing 908494 2020-11-27 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (RELEASE 4) 14,134 European ancestry cases, 1,284,876 European ancestry controls NA Affymetrix, Illumina [24600933] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST010776 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 1299010 2020-11-27 32404885 COVID-19 Host Genetics Initiative 2020-05-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32404885 The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. COVID-19 (very severe respiratory confirmed vs not hospitalized) RELEASE 4 269 European ancestry cases, 688 European ancestry controls NA Affymetrix, Illumina [9309252] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST010775 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 957 2020-07-23 32341527 Landi MT 2020-04-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32341527 Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility. Cutaneous malignant melanoma 36,760 European ancestry cases, 375,188 European ancestry controls NA Affymetrix, Illumina [NR] (imputed) 76 cutaneous melanoma http://www.ebi.ac.uk/efo/EFO_0000389 GCST010304 Genome-wide genotyping array 411948 2020-07-23 32341527 Landi MT 2020-04-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32341527 Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility. Cutaneous melanoma or hair colour 36,760 European ancestry cutaneous melanoma cases, 375,188 European ancestry controls, 352,662 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 48 cutaneous melanoma, hair color http://www.ebi.ac.uk/efo/EFO_0000389, http://www.ebi.ac.uk/efo/EFO_0003924 GCST010302 Genome-wide genotyping array 764610 2020-07-23 32341527 Landi MT 2020-04-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32341527 Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility. Nevus count or cutaneous melanoma 36,760 European ancestry cutaneous melanoma cases, 375,188 European ancestry controls, 12,930 European ancestry individuals, 52,847 individuals NA Affymetrix, Illumina [NR] (imputed) 66 nevus count, cutaneous melanoma http://www.ebi.ac.uk/efo/EFO_0004632, http://www.ebi.ac.uk/efo/EFO_0000389 GCST010303 Genome-wide genotyping array 477725 2021-01-28 32339537 Roberts V 2020-04-24 J Invest Dermatol www.ncbi.nlm.nih.gov/pubmed/32339537 Genome wide association study identifies genetic associations with perceived age. Youthful appearance (self-reported) 423,992 European ancestry individuals NA Affymetrix [~ 9600000] (imputed) 81 skin aging measurement http://www.ebi.ac.uk/efo/EFO_0008006 GCST011011 Genome-wide genotyping array 423992 2021-06-04 32989782 Goddard PC 2020-09-29 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/32989782 Integrative genomic analysis in African American children with asthma finds three novel loci associated with lung function. Lung function (FVC) in asthma 104 African American individuals NA Affymetrix [15954804] (imputed) 17 vital capacity http://www.ebi.ac.uk/efo/EFO_0004312 GCST011796 Genome-wide genotyping array 104 2021-06-04 32989782 Goddard PC 2020-09-29 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/32989782 Integrative genomic analysis in African American children with asthma finds three novel loci associated with lung function. Lung function (FEV1/FVC) in asthma 96 African American individuals NA Affymetrix [15954804] (imputed) 22 FEV/FEC ratio http://www.ebi.ac.uk/efo/EFO_0004713 GCST011797 Genome-wide genotyping array 96 2021-06-04 32989782 Goddard PC 2020-09-29 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/32989782 Integrative genomic analysis in African American children with asthma finds three novel loci associated with lung function. Post-bronchodilator lung function in asthma (FEV1) 107 African American individuals NA Affymetrix [15954804] (imputed) 8 forced expiratory volume, response to bronchodilator http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366 GCST011799 Genome-wide genotyping array 107 2021-06-04 32989782 Goddard PC 2020-09-29 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/32989782 Integrative genomic analysis in African American children with asthma finds three novel loci associated with lung function. Post-bronchodilator lung function in asthma (FVC) 109 African American individuals NA Affymetrix [15954804] (imputed) 14 response to bronchodilator, vital capacity http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004312 GCST011800 Genome-wide genotyping array 109 2021-06-04 32989782 Goddard PC 2020-09-29 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/32989782 Integrative genomic analysis in African American children with asthma finds three novel loci associated with lung function. Post-bronchodilator lung function in asthma (FEV1/FVC) 99 African American individuals NA Affymetrix [15954804] (imputed) 21 response to bronchodilator, FEV/FEC ratio http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713 GCST011801 Genome-wide genotyping array 99 2021-06-04 32989782 Goddard PC 2020-09-29 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/32989782 Integrative genomic analysis in African American children with asthma finds three novel loci associated with lung function. Lung function (FEV1) in asthma 99 African American individuals NA Affymetrix [15954804] (imputed) 11 forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0004314 GCST011798 Genome-wide genotyping array 99 2021-07-19 33075057 Li X 2020-10-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33075057 Automated feature extraction from population wearable device data identified novel loci associated with sleep and circadian rhythms. Activity variability during wake 90,515 individuals NA NR [11024754] (imputed) 1 physical activity measurement http://www.ebi.ac.uk/efo/EFO_0008002 GCST012040 Genome-wide genotyping array 90515 2021-07-19 33075057 Li X 2020-10-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33075057 Automated feature extraction from population wearable device data identified novel loci associated with sleep and circadian rhythms. Sleep duration (< 5 hours) 90,515 individuals NA NR [11024754] (imputed) 1 sleep duration http://www.ebi.ac.uk/efo/EFO_0005271 GCST012039 Genome-wide genotyping array 90515 2021-07-19 33075057 Li X 2020-10-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33075057 Automated feature extraction from population wearable device data identified novel loci associated with sleep and circadian rhythms. Sleep duration (> 10 hours) 90,515 individuals NA NR [11024754] (imputed) 5 sleep duration http://www.ebi.ac.uk/efo/EFO_0005271 GCST012038 Genome-wide genotyping array 90515 2021-07-19 33075057 Li X 2020-10-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33075057 Automated feature extraction from population wearable device data identified novel loci associated with sleep and circadian rhythms. Sleep start time 90,515 individuals NA NR [11024754] (imputed) 5 chronotype measurement http://www.ebi.ac.uk/efo/EFO_0008328 GCST012037 Genome-wide genotyping array 90515 2021-07-19 33075057 Li X 2020-10-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33075057 Automated feature extraction from population wearable device data identified novel loci associated with sleep and circadian rhythms. Sleep end time 90,515 individuals NA NR [11024754] (imputed) 4 chronotype measurement http://www.ebi.ac.uk/efo/EFO_0008328 GCST012036 Genome-wide genotyping array 90515 2021-07-19 33075057 Li X 2020-10-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33075057 Automated feature extraction from population wearable device data identified novel loci associated with sleep and circadian rhythms. Sleep (1-day periodicity) 90,515 individuals NA NR [11024754] (imputed) 5 sleep measurement http://www.ebi.ac.uk/efo/EFO_0004870 GCST012035 Genome-wide genotyping array 90515 2021-07-19 33075057 Li X 2020-10-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33075057 Automated feature extraction from population wearable device data identified novel loci associated with sleep and circadian rhythms. Sleep (1/2-day periodicity) 90,515 individuals NA NR [11024754] (imputed) 12 sleep measurement http://www.ebi.ac.uk/efo/EFO_0004870 GCST012034 Genome-wide genotyping array 90515 2021-07-19 33075057 Li X 2020-10-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33075057 Automated feature extraction from population wearable device data identified novel loci associated with sleep and circadian rhythms. Sleep (1/3-day periodicity) 90,515 individuals NA NR [11024754] (imputed) 19 sleep measurement http://www.ebi.ac.uk/efo/EFO_0004870 GCST012033 Genome-wide genotyping array 90515 2021-07-19 33075057 Li X 2020-10-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33075057 Automated feature extraction from population wearable device data identified novel loci associated with sleep and circadian rhythms. Sleep activity levels 90,515 individuals NA NR [11024754] (imputed) 4 sleep measurement http://www.ebi.ac.uk/efo/EFO_0004870 GCST012041 Genome-wide genotyping array 90515 2021-07-08 33421400 Galata G 2021-01-04 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/33421400 Genome-wide association study identifies novel susceptibility loci for KIT D816V positive mastocytosis. Mastocytosis (KIT D816V positive) 414 European ancestry cases, 9,504 European ancestry controls 621 European ancestry cases, 8,456 European ancestry controls Illumina [592007] (imputed) 7 Mastocytosis http://www.ebi.ac.uk/efo/EFO_0009001 GCST012017 Genome-wide genotyping array 9918 2021-01-21 30909962 Zuo XY 2019-03-25 Biol Sex Differ www.ncbi.nlm.nih.gov/pubmed/30909962 X-chromosome association study reveals genetic susceptibility loci of nasopharyngeal carcinoma. Nasopharyngeal carcinoma 1,615 East Asian ancestry cases and 1,025 East Asian ancestry controls 543 East Asian ancestry cases, 735 East Asian ancestry controls Illumina [111307] (imputed) 0 nasopharyngeal neoplasm http://www.ebi.ac.uk/efo/EFO_0004252 GCST010978 Targeted genotyping array 2640 2020-07-31 32349335 Lundback V 2020-04-27 Cells www.ncbi.nlm.nih.gov/pubmed/32349335 Genome-Wide Association Study of Diabetogenic Adipose Morphology in the GENetics of Adipocyte Lipolysis (GENiAL) Cohort. Adipose morphology 894 individuals NA NR [9714326] (imputed) 30 adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004764 GCST010356 Genome-wide genotyping array 894 2020-11-04 32335043 Park S 2020-04-22 J Acad Nutr Diet www.ncbi.nlm.nih.gov/pubmed/32335043 Alcohol, Carbohydrate, and Calcium Intakes and Smoking Interactions with APOA5 rs662799 and rs2266788 were Associated with Elevated Plasma Triglyceride Concentrations in a Cross-Sectional Study of Korean Adults. Triglyceride levels 21,014 Korean ancestry individuals with TG < 150mg/dL, 7,424 Korean ancestry individuals with TG ≥ 150 mg/dL NA Affymetrix [830000] 1 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST010729 Genome-wide genotyping array 28738 2020-05-28 32231278 Hysi PG 2020-03-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32231278 Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia. Refractive error 542,934 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 448 Abnormality of refraction http://purl.obolibrary.org/obo/HP_0000539 GCST010002 Genome-wide genotyping array 542934 2020-05-28 32231278 Hysi PG 2020-03-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32231278 Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia. Refractive error 351,091 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 0 Abnormality of refraction http://purl.obolibrary.org/obo/HP_0000539 GCST010003 Genome-wide genotyping array 351091 2020-06-25 32358547 Persyn E 2020-05-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32358547 Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants. White matter hyperintensities 39,011 European ancestry individuals, 2,099 African ancestry individuals, 795 Hispanic individuals, 3,299 Asian ancestry individuals NA Affymetrix [9700000] (imputed) 19 white matter hyperintensity measurement http://www.ebi.ac.uk/efo/EFO_0005665 GCST010101 Genome-wide genotyping array 45204 2020-06-25 32358547 Persyn E 2020-05-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32358547 Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants. White matter integrity (fractional anisotropy) 17,663 European ancestry individuals NA Affymetrix [NR] (imputed) 9 white matter integrity http://www.ebi.ac.uk/efo/EFO_0004641 GCST010102 Genome-wide genotyping array 17663 2020-06-25 32358547 Persyn E 2020-05-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32358547 Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants. White matter integrity (mean diffusivity) 17,467 European ancestry individuals NA Affymetrix [NR] (imputed) 6 white matter integrity http://www.ebi.ac.uk/efo/EFO_0004641 GCST010103 Genome-wide genotyping array 17467 2020-07-09 31605138 Avitabile M 2019-09-07 Carcinogenesis www.ncbi.nlm.nih.gov/pubmed/31605138 Neural crest-derived tumor neuroblastoma and melanoma share 1p13.2 as susceptibility locus that shows a long-range interaction with the SLC16A1 gene. Neuroblastoma or malignant cutaneous melanoma 2,101 European ancestry neuroblastoma cases, 12,874 European ancestry malignant cutaneous melanoma cases, 27,405 European ancestry controls 2,039 European ancestry neuroblastoma cases, 508 European ancestry malignant cutaneous melanoma cases, 3,469 European ancestry controls NR [NR] (imputed) 16 neuroblastoma, cutaneous melanoma http://www.ebi.ac.uk/efo/EFO_0000621, http://www.ebi.ac.uk/efo/EFO_0000389 GCST010152 Genome-wide genotyping array 42380 2020-12-24 28322283 Chibnik LB 2017-03-21 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/28322283 Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies. Neuritic plaque 909 European ancestry individuals 369 individuals Affymetrix, Illumina [NR] (imputed) 14 neuritic plaque measurement http://www.ebi.ac.uk/efo/EFO_0006798 GCST90012825 Genome-wide genotyping array 909 2020-12-24 28322283 Chibnik LB 2017-03-21 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/28322283 Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies. Neurofibrillary tangles 909 European ancestry individuals 369 individuals Affymetrix, Illumina [NR] (imputed) 16 neurofibrillary tangles measurement http://www.ebi.ac.uk/efo/EFO_0006797 GCST90012826 Genome-wide genotyping array 909 2020-12-24 28322283 Chibnik LB 2017-03-21 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/28322283 Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies. Diffuse plaques 909 European ancestry individuals 369 individuals Affymetrix, Illumina [NR] (imputed) 11 diffuse plaque measurement http://www.ebi.ac.uk/efo/EFO_0010699 GCST90012827 Genome-wide genotyping array 909 2020-12-24 28322283 Chibnik LB 2017-03-21 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/28322283 Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies. Cerebral amyloid angiopathy 404 European ancestry mild cases, 209 European ancestry moderate cases, 113 European ancestry severe cases, 183 European ancestry controls 369 individuals Affymetrix, Illumina [NR] (imputed) 13 cerebral amyloid angiopathy http://www.ebi.ac.uk/efo/EFO_0006790 GCST90012828 Genome-wide genotyping array 909 2020-12-24 28322283 Chibnik LB 2017-03-21 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/28322283 Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies. Microscopic brain infarct 253 European ancestry cases, 656 European ancestry controls 369 individuals Affymetrix, Illumina [NR] (imputed) 9 brain infarction http://www.ebi.ac.uk/efo/EFO_0004277 GCST90012829 Genome-wide genotyping array 909 2020-12-24 28322283 Chibnik LB 2017-03-21 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/28322283 Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies. Macroscopic brain infarct 327 European ancestry cases, 582 European ancestry controls 369 individuals Affymetrix, Illumina [NR] (imputed) 5 brain infarction http://www.ebi.ac.uk/efo/EFO_0004277 GCST90012830 Genome-wide genotyping array 909 2020-12-24 28322283 Chibnik LB 2017-03-21 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/28322283 Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies. Dementia with Lewy bodies 195 European ancestry cases, 714 European ancestry controls 369 individuals Affymetrix, Illumina [NR] (imputed) 13 Lewy body dementia http://www.ebi.ac.uk/efo/EFO_0006792 GCST90012831 Genome-wide genotyping array 909 2020-12-24 28322283 Chibnik LB 2017-03-21 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/28322283 Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies. Neuropathologic traits (pleiotropy) 909 European ancestry individuals 369 individuals Affymetrix, Illumina [NR] (imputed) 22 brain infarction, neuritic plaque measurement, Lewy body dementia, cerebral amyloid angiopathy, neurofibrillary tangles measurement http://www.ebi.ac.uk/efo/EFO_0004277, http://www.ebi.ac.uk/efo/EFO_0006798, http://www.ebi.ac.uk/efo/EFO_0006792, http://www.ebi.ac.uk/efo/EFO_0006790, http://www.ebi.ac.uk/efo/EFO_0006797 GCST90012832 Genome-wide genotyping array 909 2021-01-05 30679421 Felsky D 2019-01-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30679421 Neuropathological correlates and genetic architecture of microglial activation in elderly human brain. Proportion of activated microglia (midfrontal cortex) 225 individuals NA NR [NR] (imputed) 12 microglial activation measurement http://www.ebi.ac.uk/efo/EFO_0010940 GCST010917 Genome-wide genotyping array 225 2021-01-05 30679421 Felsky D 2019-01-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30679421 Neuropathological correlates and genetic architecture of microglial activation in elderly human brain. Proportion of activated microglia (inferior temporal cortex) 219 individuals NA NR [NR] (imputed) 26 microglial activation measurement http://www.ebi.ac.uk/efo/EFO_0010940 GCST010916 Genome-wide genotyping array 219 2021-03-28 32757270 Ruiz-Pinto S 2020-08-05 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/32757270 Regulatory CDH4 genetic variants associate with risk to develop capecitabine-induced hand-foot syndrome. Capecitabine-induced hand-foot syndrome in breast or colorectal cancer 88 cases, 78 controls 24 cases, 61 controls Illumina [520052] 4 Hand-foot syndrome, response to fluoropyrimidines http://www.ebi.ac.uk/efo/EFO_1001893, http://www.ebi.ac.uk/efo/EFO_0010825 GCST011420 Genome-wide genotyping array 166 2021-02-18 33410475 Mangantig E 2021-01-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33410475 Germline variants are associated with increased primary melanoma tumor thickness at diagnosis. Breslow thickness in cutaneous melanoma 8,505 European ancestry individuals NA Illumina [13517544] (imputed) 1 Breslow thickness http://www.ebi.ac.uk/efo/EFO_0004955 GCST011123 Genome-wide genotyping array 8505 2021-01-11 33307546 Pairo-Castineira E 2020-12-11 Nature www.ncbi.nlm.nih.gov/pubmed/33307546 Genetic mechanisms of critical illness in Covid-19. COVID-19 (critical illness vs population) 2,804 European ancestry cases, 2,415 European, South Asian and Hispanic or Latin American ancestry cases, 687,911 European ancestry controls, 477,741 European, South Asian and Hispanic or Latin American ancestry controls NA Illumina [NR] (imputed) 6 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST010936 Genome-wide genotyping array 1170871 2021-01-11 33307546 Pairo-Castineira E 2020-12-11 Nature www.ncbi.nlm.nih.gov/pubmed/33307546 Genetic mechanisms of critical illness in Covid-19. COVID-19 (critical illness vs population) 182 African ancestry cases, 910 African ancestry controls NA Illumina [4700000] (imputed) 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST90013412 Genome-wide genotyping array 1092 2021-01-11 33307546 Pairo-Castineira E 2020-12-11 Nature www.ncbi.nlm.nih.gov/pubmed/33307546 Genetic mechanisms of critical illness in Covid-19. COVID-19 (critical illness vs population) 149 East Asian ancestry cases, 745 East Asian ancestry controls NA Illumina [4700000] (imputed) 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST90013413 Genome-wide genotyping array 894 2021-01-11 33307546 Pairo-Castineira E 2020-12-11 Nature www.ncbi.nlm.nih.gov/pubmed/33307546 Genetic mechanisms of critical illness in Covid-19. COVID-19 (critical illness vs population) 1,676 European ancestry cases, 8,380 European ancestry controls 2,415 European, South Asian and Hispanic or Latin American ancestry cases, 477,741 European, South Asian and Hispanic or Latin American ancestry controls, 1,128 European ancestry cases, 679,531 European ancestry controls Illumina [4700000] (imputed) 2 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST90013414 Genome-wide genotyping array 10056 2021-01-11 33307546 Pairo-Castineira E 2020-12-11 Nature www.ncbi.nlm.nih.gov/pubmed/33307546 Genetic mechanisms of critical illness in Covid-19. COVID-19 (critical illness vs population) 237 South Asian ancestry cases, 1,185 South Asian ancestry controls NA Illumina [4700000] (imputed) 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST90013415 Genome-wide genotyping array 1422 2020-08-03 32352494 Han X 2020-04-30 JAMA Ophthalmol www.ncbi.nlm.nih.gov/pubmed/32352494 Association of Myopia and Intraocular Pressure With Retinal Detachment in European Descent Participants of the UK Biobank Cohort: A Mendelian Randomization Study. Retinal detachment 4,257 European ancestry cases, 39,181 European ancestry controls NA NR [NR] 2 retinal detachment http://www.ebi.ac.uk/efo/EFO_0005773 GCST010377 Genome-wide genotyping array 43438 2020-08-03 32352494 Han X 2020-04-30 JAMA Ophthalmol www.ncbi.nlm.nih.gov/pubmed/32352494 Association of Myopia and Intraocular Pressure With Retinal Detachment in European Descent Participants of the UK Biobank Cohort: A Mendelian Randomization Study. Spherical equivalent 95,827 European ancestry individuals NA NR [NR] 224 refractive error measurement http://www.ebi.ac.uk/efo/EFO_0007814 GCST010378 Genome-wide genotyping array 95827 2020-08-03 32352494 Han X 2020-04-30 JAMA Ophthalmol www.ncbi.nlm.nih.gov/pubmed/32352494 Association of Myopia and Intraocular Pressure With Retinal Detachment in European Descent Participants of the UK Biobank Cohort: A Mendelian Randomization Study. Intraocular pressure 101,939 European ancestry cases NA NR [NR] 99 intraocular pressure measurement http://www.ebi.ac.uk/efo/EFO_0004695 GCST010376 Genome-wide genotyping array 101939 2021-07-13 33048379 Richard MA 2020-10-13 Cancer www.ncbi.nlm.nih.gov/pubmed/33048379 Genetic variation in the body mass index of adult survivors of childhood acute lymphoblastic leukemia: A report from the Childhood Cancer Survivor Study and the St. Jude Lifetime Cohort. BMI in adult survivors of childhood acute lymphoblastic leukemia treated with cranial radiation 962 European ancestry individuals 260 individuals Illumina [> 9000000] (imputed) 2 body mass index, response to cranial radiation therapy http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0010950 GCST012027 Genome-wide genotyping array 962 2021-07-13 33048379 Richard MA 2020-10-13 Cancer www.ncbi.nlm.nih.gov/pubmed/33048379 Genetic variation in the body mass index of adult survivors of childhood acute lymphoblastic leukemia: A report from the Childhood Cancer Survivor Study and the St. Jude Lifetime Cohort. BMI in adult survivors of childhood acute lymphoblastic leukemia not treated with cranial radiation 496 European ancestry individuals 527 individuals Illumina [> 9000000] (imputed) 1 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST012026 Genome-wide genotyping array 496 2021-07-13 33048379 Richard MA 2020-10-13 Cancer www.ncbi.nlm.nih.gov/pubmed/33048379 Genetic variation in the body mass index of adult survivors of childhood acute lymphoblastic leukemia: A report from the Childhood Cancer Survivor Study and the St. Jude Lifetime Cohort. BMI in adult survivors of childhood acute lymphoblastic leukemia 1,458 European ancestry individuals 787 individuals Illumina [> 9000000] (imputed) 4 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST012028 Genome-wide genotyping array 1458 2021-02-24 33407712 Liang X 2021-01-06 Mol Brain www.ncbi.nlm.nih.gov/pubmed/33407712 Evaluating the genetic effects of sex hormone traits on the development of mental traits: a polygenic score analysis and gene-environment-wide interaction study in UK Biobank cohort. Testosterone levels x fluid intelligence interaction 160,121 British ancestry individuals NA Affymetrix [NR] (imputed) 1 intelligence, testosterone measurement http://www.ebi.ac.uk/efo/EFO_0004337, http://www.ebi.ac.uk/efo/EFO_0004908 GCST011153 Genome-wide genotyping array 160121 2021-02-24 33407712 Liang X 2021-01-06 Mol Brain www.ncbi.nlm.nih.gov/pubmed/33407712 Evaluating the genetic effects of sex hormone traits on the development of mental traits: a polygenic score analysis and gene-environment-wide interaction study in UK Biobank cohort. Testosterone levels x alcohol consumption (drinks per week) interaction 388,571 British ancestry individuals NA Affymetrix [NR] (imputed) 2 alcohol consumption measurement, testosterone measurement http://www.ebi.ac.uk/efo/EFO_0007878, http://www.ebi.ac.uk/efo/EFO_0004908 GCST011152 Genome-wide genotyping array 388571 2021-02-24 33407712 Liang X 2021-01-06 Mol Brain www.ncbi.nlm.nih.gov/pubmed/33407712 Evaluating the genetic effects of sex hormone traits on the development of mental traits: a polygenic score analysis and gene-environment-wide interaction study in UK Biobank cohort. Testosterone levels x smoking behaviour (cigarettes smoked per day) interaction 414,294 British ancestry individuals NA Affymetrix [NR] (imputed) 2 smoking behaviour measurement, testosterone measurement http://www.ebi.ac.uk/efo/EFO_0005671, http://www.ebi.ac.uk/efo/EFO_0004908 GCST011151 Genome-wide genotyping array 414294 2021-02-24 33407712 Liang X 2021-01-06 Mol Brain www.ncbi.nlm.nih.gov/pubmed/33407712 Evaluating the genetic effects of sex hormone traits on the development of mental traits: a polygenic score analysis and gene-environment-wide interaction study in UK Biobank cohort. Bioavailable testosterone levels x smoking behaviour (cigarettes smoked per day) interaction 414,294 British ancestry individuals NA Affymetrix [NR] (imputed) 0 smoking behaviour measurement, testosterone measurement http://www.ebi.ac.uk/efo/EFO_0005671, http://www.ebi.ac.uk/efo/EFO_0004908 GCST011150 Genome-wide genotyping array 414294 2021-02-24 33407712 Liang X 2021-01-06 Mol Brain www.ncbi.nlm.nih.gov/pubmed/33407712 Evaluating the genetic effects of sex hormone traits on the development of mental traits: a polygenic score analysis and gene-environment-wide interaction study in UK Biobank cohort. Bioavailable testosterone levels x alcohol consumption (drinks per week) interaction 388,571 British ancestry individuals NA Affymetrix [NR] (imputed) 0 alcohol consumption measurement, testosterone measurement http://www.ebi.ac.uk/efo/EFO_0007878, http://www.ebi.ac.uk/efo/EFO_0004908 GCST011149 Genome-wide genotyping array 388571 2021-02-24 33407712 Liang X 2021-01-06 Mol Brain www.ncbi.nlm.nih.gov/pubmed/33407712 Evaluating the genetic effects of sex hormone traits on the development of mental traits: a polygenic score analysis and gene-environment-wide interaction study in UK Biobank cohort. Bioavailable testosterone levels x fluid intelligence interaction 160,121 British ancestry individuals NA Affymetrix [NR] (imputed) 0 intelligence, testosterone measurement http://www.ebi.ac.uk/efo/EFO_0004337, http://www.ebi.ac.uk/efo/EFO_0004908 GCST011148 Genome-wide genotyping array 160121 2021-02-24 33407712 Liang X 2021-01-06 Mol Brain www.ncbi.nlm.nih.gov/pubmed/33407712 Evaluating the genetic effects of sex hormone traits on the development of mental traits: a polygenic score analysis and gene-environment-wide interaction study in UK Biobank cohort. Estradiol levels x smoking behaviour (cigarettes smoked per day) interaction 185,464 British ancestry men NA Affymetrix [NR] (imputed) 0 smoking behaviour measurement, estradiol measurement http://www.ebi.ac.uk/efo/EFO_0005671, http://www.ebi.ac.uk/efo/EFO_0004697 GCST011147 Genome-wide genotyping array 185464 2021-02-24 33407712 Liang X 2021-01-06 Mol Brain www.ncbi.nlm.nih.gov/pubmed/33407712 Evaluating the genetic effects of sex hormone traits on the development of mental traits: a polygenic score analysis and gene-environment-wide interaction study in UK Biobank cohort. Estradiol levels x alcohol consumption (drinks per week) interaction 189,153 British ancestry men NA Affymetrix [NR] (imputed) 0 alcohol consumption measurement, estradiol measurement http://www.ebi.ac.uk/efo/EFO_0007878, http://www.ebi.ac.uk/efo/EFO_0004697 GCST011146 Genome-wide genotyping array 189153 2021-02-24 33407712 Liang X 2021-01-06 Mol Brain www.ncbi.nlm.nih.gov/pubmed/33407712 Evaluating the genetic effects of sex hormone traits on the development of mental traits: a polygenic score analysis and gene-environment-wide interaction study in UK Biobank cohort. Estradiol levels x fluid intelligence interaction 73,236 British ancestry men NA Affymetrix [NR] (imputed) 0 intelligence, estradiol measurement http://www.ebi.ac.uk/efo/EFO_0004337, http://www.ebi.ac.uk/efo/EFO_0004697 GCST011145 Genome-wide genotyping array 73236 2021-02-24 33407712 Liang X 2021-01-06 Mol Brain www.ncbi.nlm.nih.gov/pubmed/33407712 Evaluating the genetic effects of sex hormone traits on the development of mental traits: a polygenic score analysis and gene-environment-wide interaction study in UK Biobank cohort. Sex hormone-binding globulin levels x smoking behaviour (cigarettes smoked per day) interaction 414,294 British ancestry individuals NA Affymetrix [NR] (imputed) 0 smoking behaviour measurement, sex hormone-binding globulin measurement http://www.ebi.ac.uk/efo/EFO_0005671, http://www.ebi.ac.uk/efo/EFO_0004696 GCST011144 Genome-wide genotyping array 414294 2021-02-24 33407712 Liang X 2021-01-06 Mol Brain www.ncbi.nlm.nih.gov/pubmed/33407712 Evaluating the genetic effects of sex hormone traits on the development of mental traits: a polygenic score analysis and gene-environment-wide interaction study in UK Biobank cohort. Sex hormone-binding globulin levels x alcohol consumption (drinks per week) interaction 388,571 British ancestry individuals NA Affymetrix [NR] (imputed) 0 alcohol consumption measurement, sex hormone-binding globulin measurement http://www.ebi.ac.uk/efo/EFO_0007878, http://www.ebi.ac.uk/efo/EFO_0004696 GCST011143 Genome-wide genotyping array 388571 2021-02-24 33407712 Liang X 2021-01-06 Mol Brain www.ncbi.nlm.nih.gov/pubmed/33407712 Evaluating the genetic effects of sex hormone traits on the development of mental traits: a polygenic score analysis and gene-environment-wide interaction study in UK Biobank cohort. Sex hormone-binding globulin levels x fluid intelligence interaction 160,121 British ancestry individuals NA Affymetrix [NR] (imputed) 0 intelligence, sex hormone-binding globulin measurement http://www.ebi.ac.uk/efo/EFO_0004337, http://www.ebi.ac.uk/efo/EFO_0004696 GCST011142 Genome-wide genotyping array 160121 2019-03-12 30670697 Kilpelainen TO 2019-01-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30670697 Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. HDL cholesterol x physical activity interaction (2df test) 7,395 African American inactive individuals, 13,092 African American active individuals, 2,753 Asian ancestry inactive individuals, 3,650 Asian ancestry active individuals, 22,963 European ancestry inactive individuals, 61,939 European ancestry active individuals, 2,829 Hispanic or Latin American inactive individuals, 6,358 Hispanic or Latin American active individuals 1,886 African American inactive individuals, 1,892 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,494 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals, 724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 41,042 European ancestry inactive individuals, 66,575 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,802 Hispanic active individuals Affymetrix, Illumina [at least 2500000] (imputed) 42 HDL cholesterol change measurement, physical activity http://www.ebi.ac.uk/efo/EFO_0007805, http://www.ebi.ac.uk/efo/EFO_0003940 GCST007282 Genome-wide genotyping array 120979 2019-03-12 30670697 Kilpelainen TO 2019-01-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30670697 Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. LDL cholesterol x physical activity interaction (2df test) 7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals 571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals, 724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals Affymetrix, Illumina [at least 2500000] (imputed) 39 low density lipoprotein cholesterol measurement, physical activity http://www.ebi.ac.uk/efo/EFO_0004611, http://www.ebi.ac.uk/efo/EFO_0003940 GCST007284 Genome-wide genotyping array 109688 2019-03-12 30670697 Kilpelainen TO 2019-01-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30670697 Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. Triglycerides x physical activity interaction (2df test) 7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals 580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals, 724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals Affymetrix, Illumina [at least 2500000] (imputed) 24 triglyceride measurement, physical activity http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0003940 GCST007286 Genome-wide genotyping array 102281 2019-03-12 30670697 Kilpelainen TO 2019-01-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30670697 Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. LDL cholesterol x physical activity interaction (1df test) 7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals 571 African American inactive individuals, 1,521 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,495 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals, 724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 33,796 European ancestry inactive individuals, 50,812 European ancestry active individuals, 2,578 Hispanic inactive individuals, 8,661 Hispanic active individuals Affymetrix, Illumina [at least 2500000] (imputed) 1 low density lipoprotein cholesterol measurement, physical activity http://www.ebi.ac.uk/efo/EFO_0004611, http://www.ebi.ac.uk/efo/EFO_0003940 GCST007283 Genome-wide genotyping array 109688 2019-03-12 30670697 Kilpelainen TO 2019-01-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30670697 Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. HDL cholesterol x physical activity interaction (1df test) 7,395 African American inactive individuals, 13,092 African American active individuals, 2,753 Asian ancestry inactive individuals, 3,650 Asian ancestry active individuals, 22,963 European ancestry inactive individuals, 61,939 European ancestry active individuals, 2,829 Hispanic or Latin American inactive individuals, 6,358 Hispanic or Latin American active individuals 1,886 African American inactive individuals, 1,892 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 2,494 East Asian ancestry inactive individuals, 1,947 East Asian ancestry active individuals, 724 South Asian ancestry inactive individuals, 1,425 South Asian ancestry active individuals, 41,042 European ancestry inactive individuals, 66,575 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,802 Hispanic active individuals Affymetrix, Illumina [at least 2500000] (imputed) 3 physical activity, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0003940, http://www.ebi.ac.uk/efo/EFO_0004612 GCST007281 Genome-wide genotyping array 120979 2019-03-12 30670697 Kilpelainen TO 2019-01-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30670697 Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. Triglycerides x physical activity interaction (1df test) 7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals 580 African American inactive individuals, 1,540 African American active individuals, 1,217 South African Black ancestry inactive individuals, 389 South African Black ancestry active individuals, 765 East Asian ancestry inactive individuals, 1,814 East Asian ancestry active individuals, 724 South Asian ancestry inactive individuals, 1,424 South Asian ancestry active individuals, 32,456 European ancestry inactive individuals, 49,510 European ancestry active individuals, 2,619 Hispanic inactive individuals, 8,803 Hispanic active individuals Affymetrix, Illumina [at least 2500000] (imputed) 0 triglyceride measurement, physical activity http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0003940 GCST007285 Genome-wide genotyping array 102281 2020-02-12 31735061 Liu X 2019-11-16 Aust N Z J Psychiatry www.ncbi.nlm.nih.gov/pubmed/31735061 Wnt receptor gene FZD1 was associated with schizophrenia in genome-wide SNP analysis of the Australian Schizophrenia Research Bank cohort. Schizophrenia 429 European ancestry cases, 255 European ancestry controls NR Illumina [6473404] (imputed) 1 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST009603 Genome-wide genotyping array 684 2020-02-07 31748690 Purves KL 2019-11-20 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/31748690 A major role for common genetic variation in anxiety disorders. Lifetime anxiety disorder 25,453 European ancestry cases, 58,113 European ancestry controls 6,524 cases, 24001 controls Illumina [NR] (imputed) 5 anxiety disorder http://www.ebi.ac.uk/efo/EFO_0006788 GCST009575 Genome-wide genotyping array 83566 2020-02-07 31748690 Purves KL 2019-11-20 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/31748690 A major role for common genetic variation in anxiety disorders. Anxiety symptoms 19,012 European ancestry cases, 58,113 European ancestry controls NA Illumina [NR] (imputed) 1 anxiety disorder measurement http://www.ebi.ac.uk/efo/EFO_0007795 GCST009574 Genome-wide genotyping array 77125 2020-02-13 31738745 Gibson J 2019-11-18 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31738745 A meta-analysis of genome-wide association studies of epigenetic age acceleration. Intrinsic epigenetic age acceleration 13,493 European ancestry individuals NA Illumina [5932107] (imputed) 10 aging http://purl.obolibrary.org/obo/GO_0007568 GCST009604 Genome-wide genotyping array 13493 2020-02-13 31738745 Gibson J 2019-11-18 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31738745 A meta-analysis of genome-wide association studies of epigenetic age acceleration. Extrinsic epigenetic age acceleration 13,493 European ancestry individuals NA Illumina [5931171] (imputed) 1 aging http://purl.obolibrary.org/obo/GO_0007568 GCST009605 Genome-wide genotyping array 13493 2019-03-02 30680360 McCoy TH Jr 2018-05-29 JBMR Plus www.ncbi.nlm.nih.gov/pubmed/30680360 Genomewide Association Study of Fracture Nonunion Using Electronic Health Records. Nonunion in individuals with fractures 131 Northern European ancestry cases, 1,629 Northern European ancestry controls NA Illumina [893900] (imputed) 44 fractures, ununited http://www.ebi.ac.uk/efo/EFO_0009707 GCST007250 Genome-wide genotyping array 1760 2019-02-15 30306274 Shah RL 2018-10-10 Hum Genet www.ncbi.nlm.nih.gov/pubmed/30306274 Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci. Corneal astigmatism 69,140 European ancestry cases, 17,195 European ancestry controls NA NR [5921785] (imputed) 10 Corneal astigmatism http://www.ebi.ac.uk/efo/EFO_1002040 GCST007157 Genome-wide genotyping array 86335 2019-02-15 30306274 Shah RL 2018-10-10 Hum Genet www.ncbi.nlm.nih.gov/pubmed/30306274 Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci. Refractive astigmatism 70,505 European ancestry cases, 17,500 European ancestry controls NA NR [5919636] (imputed) 10 Astigmatism http://purl.obolibrary.org/obo/HP_0000483 GCST007158 Genome-wide genotyping array 88005 2019-02-15 30306274 Shah RL 2018-10-10 Hum Genet www.ncbi.nlm.nih.gov/pubmed/30306274 Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci. Corneal astigmatism Up to 86,335 European ancestry individuals NA NR [5901671] (imputed) 32 Corneal astigmatism http://www.ebi.ac.uk/efo/EFO_1002040 GCST007159 Genome-wide genotyping array 86335 2019-02-15 30306274 Shah RL 2018-10-10 Hum Genet www.ncbi.nlm.nih.gov/pubmed/30306274 Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci. Refractive astigmatism 88,005 European ancestry individuals NA NR [5900115] (imputed) 34 Astigmatism http://purl.obolibrary.org/obo/HP_0000483 GCST007160 Genome-wide genotyping array 88005 2020-01-28 31738830 McGraw KL 2019-11-01 Blood Adv www.ncbi.nlm.nih.gov/pubmed/31738830 Non-del(5q) myelodysplastic syndromes-associated loci detected by SNP-array genome-wide association meta-analysis. Non-del(5q) myelodysplastic syndromes 907 European ancestry cases, 5,605 European ancestry controls NA Affymetrix [7515136] (imputed) 8 myelodysplastic syndrome http://www.ebi.ac.uk/efo/EFO_0000198 GCST009516 Genome-wide genotyping array 6512 2020-02-19 31757997 Low SK 2019-11-22 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31757997 Identification of two novel breast cancer loci through large-scale genome-wide association study in the Japanese population. Breast cancer 6,669 Japanese ancestry cases, 21,930 Japanese ancestry controls 981 Japanese ancestry cases, 1,394 Japanese ancestry controls Illumina [4946503] (imputed) 25 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST009665 Genome-wide genotyping array 28599 2019-12-17 31740666 Cheng Z 2019-11-18 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31740666 A regulatory variant of CHRM3 is associated with cannabis-induced hallucinations in European Americans. Hallucinations in long-term cannabis use 91 European ancestry cases, 220 African American cases, 1,826 European ancestry controls, 2,148 African American controls 256 European ancestry cases, 142 African American cases, 2,118 European ancestry controls, 1,114 African American controls Illumina [up to 14134502] (imputed) 2 Hallucinations http://purl.obolibrary.org/obo/HP_0000738 GCST009314 Genome-wide genotyping array 4285 2019-12-18 31748705 Ohta Y 2019-11-20 Hypertens Res www.ncbi.nlm.nih.gov/pubmed/31748705 Genetic factors associated with elevation of uric acid after treatment with thiazide-like diuretic in patients with essential hypertension. Uric acid elevation in response to thiazide-like diuretic in hypertension 73 Japanese ancestry responders, 53 Japanese ancestry non-responders NA Affymetrix [290698] 2 response to diuretic, uric acid measurement http://purl.obolibrary.org/obo/GO_0036270, http://www.ebi.ac.uk/efo/EFO_0004761 GCST009319 Genome-wide genotyping array 126 2018-05-11 29531279 Zhou S 2018-03-12 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29531279 Genome-wide association analysis identifies new candidate risk loci for familial intracranial aneurysm in the French-Canadian population. Intracranial aneurysm 173 French Canadian cases, 1,772 French Canadian controls 2,617 cases, 1,416 controls Illumina [7614484] (imputed) 31 brain aneurysm http://www.ebi.ac.uk/efo/EFO_0003870 GCST005576 Genome-wide genotyping array 1945 2021-02-17 31420016 Kisia LE 2019-08-16 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/31420016 Genetic variation in interleukin-7 is associated with a reduced erythropoietic response in Kenyan children infected with Plasmodium falciparum. Severe malarial anemia in Plasmodium falciparum infection 70 child cases, 74 child controls 165 Kenyan ancestry child cases, 718 Kenyan ancestry child controls Illumina [NR] 0 severe malarial anemia http://www.ebi.ac.uk/efo/EFO_0010970 GCST011118 Genome-wide genotyping array 144 2019-09-05 30690781 Pei YF 2019-02-28 J Bone Miner Res www.ncbi.nlm.nih.gov/pubmed/30690781 Joint Association Analysis Identified 18 New Loci for Bone Mineral Density. Total body bone mineral density (MTAG) at least 66,628 individuals NA NR [9704453] 17 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST008603 Genome-wide genotyping array 66628 2019-09-05 30690781 Pei YF 2019-02-28 J Bone Miner Res www.ncbi.nlm.nih.gov/pubmed/30690781 Joint Association Analysis Identified 18 New Loci for Bone Mineral Density. Heel bone mineral density (MTAG) at least 142,487 individuals NA NR [9704453] 17 heel bone mineral density http://www.ebi.ac.uk/efo/EFO_0009270 GCST008602 Genome-wide genotyping array 142487 2021-03-18 31426789 Jeong KH 2019-08-19 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/31426789 Genome-wide association study identifies new susceptible loci of IgA nephropathy in Koreans. IgA nephropathy 188 Korean ancestry cases, 455 Korean ancestry controls 310 Korean ancestry cases, 438 Korean ancestry controls Affymetrix [98667] 0 IGA glomerulonephritis http://www.ebi.ac.uk/efo/EFO_0004194 GCST011296 Genome-wide genotyping array 643 2019-09-10 30945665 Bandesh K 2019-03-01 J Genet www.ncbi.nlm.nih.gov/pubmed/30945665 Genomewide association study of C-peptide surfaces key regulatory genes in Indians. C-peptide levels 877 Indo-European ancestry individuals 1,829 Indo-European ancestry individuals, 773 Hispanic individuals Illumina [552011] 1 C-peptide measurement http://www.ebi.ac.uk/efo/EFO_0005187 GCST008641 Genome-wide genotyping array 877 2020-02-14 31815349 Chen VL 2019-12-09 Liver Int www.ncbi.nlm.nih.gov/pubmed/31815349 Genetic variants that associate with liver cirrhosis have pleiotropic effects on human traits. Cirrhosis 1,088 British ancestry cases, 407,873 British ancestry controls 875 European ancestry cases, 30,346 European ancestry controls Affymetrix [18530078] (imputed) 1 cirrhosis of liver http://www.ebi.ac.uk/efo/EFO_0001422 GCST009609 Genome-wide genotyping array 408961 2020-02-17 31813042 Wang L 2019-12-07 Mol Genet Genomics www.ncbi.nlm.nih.gov/pubmed/31813042 Additional common loci associated with stroke and obesity identified using pleiotropic analytical approach. Stroke and BMI (pleiotropy) 40,585 European ancestry stroke cases, 406,111 European ancestry controls, 681,275 European ancestry individuals NA NR [114466] (imputed) 0 stroke, body mass index http://www.ebi.ac.uk/efo/EFO_0000712, http://www.ebi.ac.uk/efo/EFO_0004340 GCST009639 Genome-wide genotyping array 1127971 2020-02-27 31830031 Chernus JM 2019-12-12 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31830031 A candidate gene analysis and GWAS for genes associated with maternal nondisjunction of chromosome 21. Maternal nondisjunction of chromosome 21 (mothers vs fathers) 705 mothers, 645 fathers NA Illumina [NR] (imputed) 14 Abnormality of chromosome segregation http://purl.obolibrary.org/obo/HP_0002916 GCST009704 Genome-wide genotyping array 1350 2020-02-27 31830031 Chernus JM 2019-12-12 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31830031 A candidate gene analysis and GWAS for genes associated with maternal nondisjunction of chromosome 21. Maternal nondisjunction of chromosome 21 (MI error vs fathers) 535 mothers, 645 fathers NA Illumina [NR] (imputed) 10 Abnormality of chromosome segregation http://purl.obolibrary.org/obo/HP_0002916 GCST009707 Genome-wide genotyping array 1180 2020-02-27 31830031 Chernus JM 2019-12-12 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31830031 A candidate gene analysis and GWAS for genes associated with maternal nondisjunction of chromosome 21. Maternal nondisjunction of chromosome 21 (MII error vs fathers) 157 mothers, 645 fathers NA Illumina [NR] (imputed) 13 Abnormality of chromosome segregation http://purl.obolibrary.org/obo/HP_0002916 GCST009706 Genome-wide genotyping array 802 2020-02-27 31830031 Chernus JM 2019-12-12 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31830031 A candidate gene analysis and GWAS for genes associated with maternal nondisjunction of chromosome 21. Maternal nondisjunction of chromosome 21 (MI error vs MII error) 535 mothers (meiosis I error), 157 mothers (meiosis II error) NA Illumina [NR] (imputed) 10 Abnormality of chromosome segregation http://purl.obolibrary.org/obo/HP_0002916 GCST009705 Genome-wide genotyping array 692 2020-02-06 31832568 Gawrieh S 2019-11-03 Hepatol Commun www.ncbi.nlm.nih.gov/pubmed/31832568 A Pilot Genome-Wide Analysis Study Identifies Loci Associated With Response to Obeticholic Acid in Patients With NASH. NASH resolution in nonalcoholic steatohepatitis 25 European ancestry cases, 116 European ancestry controls NA Illumina [5417859] (imputed) 4 remission http://www.ebi.ac.uk/efo/EFO_0009785 GCST009548 Genome-wide genotyping array 141 2020-02-06 31832568 Gawrieh S 2019-11-03 Hepatol Commun www.ncbi.nlm.nih.gov/pubmed/31832568 A Pilot Genome-Wide Analysis Study Identifies Loci Associated With Response to Obeticholic Acid in Patients With NASH. Pruritus in nonalcoholic steatohepatitis approximately 31 European ancestry cases, approximately 166 European ancestry controls NA Illumina [5417859] (imputed) 1 Pruritus http://purl.obolibrary.org/obo/HP_0000989 GCST009549 Genome-wide genotyping array 197 2020-02-06 31832568 Gawrieh S 2019-11-03 Hepatol Commun www.ncbi.nlm.nih.gov/pubmed/31832568 A Pilot Genome-Wide Analysis Study Identifies Loci Associated With Response to Obeticholic Acid in Patients With NASH. Fibrosis improvement in nonalcoholic steatohepatitis 38 European ancestry cases, 103 European ancestry controls NA Illumina [5417859] (imputed) 2 liver fibrosis measurement http://www.ebi.ac.uk/efo/EFO_0010576 GCST009547 Genome-wide genotyping array 141 2020-03-03 28369058 Folkersen L 2017-04-03 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28369058 Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease. Blood protein levels in cardiovascular risk 3,394 European ancestry individuals 2,639 individuals Illumina [5270624] (imputed) 77 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST009731 Targeted genotyping array [Immunochip, Cardio-MetaboChip] 3394 2020-01-08 31790847 Hou R 2019-11-29 Bone www.ncbi.nlm.nih.gov/pubmed/31790847 Genetic variants affecting bone mineral density and bone mineral content at multiple skeletal sites in Hispanic children. Bone mineral content 1,030 Hispanic or Latin American children NA Illumina [> 1100000] 29 bone mineral content measurement http://www.ebi.ac.uk/efo/EFO_0007621 GCST009378 Genome-wide genotyping array, Exome-wide sequencing 1030 2020-01-08 31790847 Hou R 2019-11-29 Bone www.ncbi.nlm.nih.gov/pubmed/31790847 Genetic variants affecting bone mineral density and bone mineral content at multiple skeletal sites in Hispanic children. Bone mineral density 1,030 Hispanic or Latin American children NA Illumina [> 1100000] 10 volumetric bone mineral density http://www.ebi.ac.uk/efo/EFO_0007620 GCST009377 Genome-wide genotyping array, Exome-wide sequencing 1030 2020-11-24 30938820 Qian M 2019-04-02 J Natl Cancer Inst www.ncbi.nlm.nih.gov/pubmed/30938820 Genome-wide association study of susceptibility loci for T-cell acute lymphoblastic leukemia in children. T-cell acute lymphoblastic leukaemia 157 African American child cases, 699 European ancestry child cases, 126 Hispanic child cases, 209 child cases, 12,178 European, African American and unknown ancestry controls 26 African American child cases, 75 European ancestry child cases, 9 Hispanic child cases, 7 child cases, 5,518 European, African American and unknown ancestry controls Affymetrix, Illumina [7967910] (imputed) 0 childhood T acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_1001947 GCST010756 Genome-wide genotyping array 13369 2020-01-23 26567291 Jensen RA 2015-11-13 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/26567291 Novel Genetic Loci Associated With Retinal Microvascular Diameter. Central retinal vein equivalent 14,740 European ancestry individuals, 5,113 Asian ancestry individuals, 3,345 African American individuals, 1,077 Hispanic individuals 5,472 European ancestry individuals Illumina [223566] 4 retinal vasculature measurement http://www.ebi.ac.uk/efo/EFO_0010554 GCST009474 Exome genotyping array 24275 2020-01-23 26567291 Jensen RA 2015-11-13 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/26567291 Novel Genetic Loci Associated With Retinal Microvascular Diameter. Central retinal arteriolar equivalent 14,740 European ancestry individuals, 5,113 Asian ancestry individuals, 3,345 African American individuals, 1,077 Hispanic individuals 5,472 European ancestry individuals Illumina [240931] 1 retinal vasculature measurement http://www.ebi.ac.uk/efo/EFO_0010554 GCST009475 Exome genotyping array 24275 2020-04-17 31932636 Hebbar P 2020-01-13 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31932636 Genome-wide association study identifies novel risk variants from RPS6KA1, CADPS, VARS, and DHX58 for fasting plasma glucose in Arab population. Fasting plasma glucose 1,353 Arab ancestry individuals 1,176 Arab ancestry individuals Illumina [632375] 9 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST009864 Genome-wide genotyping array 1353 2019-12-23 31740837 Lam M 2019-11-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31740837 Comparative genetic architectures of schizophrenia in East Asian and European populations. Schizophrenia 22,778 East Asian ancestry cases, 35,362 East Asian ancestry controls NA Affymetrix, Illumina [9938587] (imputed) 21 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST009336 Genome-wide genotyping array 58140 2019-12-23 31740837 Lam M 2019-11-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31740837 Comparative genetic architectures of schizophrenia in East Asian and European populations. Schizophrenia 22,778 East Asian ancestry cases, 35,362 East Asian ancestry controls, 33,640 European ancestry cases, 43,456 European ancestry controls NA Affymetrix, Illumina [12447948] (imputed) 208 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST009337 Genome-wide genotyping array 135236 2020-04-17 31826910 Lu Y 2019-12-11 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/31826910 Identification of novel loci and new risk variant in known loci for colorectal cancer risk in East Asians. Colorectal cancer 23,572 East Asian ancestry cases, 48,700 East Asian ancestry controls 58,131 European ancestry cases, 67,347 European ancestry controls Affymetrix, Illumina [up to 47000000] (imputed) 70 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST009869 Genome-wide genotyping array 72272 2020-01-15 30456811 Moss LC 2018-11-19 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30456811 Using Bayes model averaging to leverage both gene main effects and G ×  E interactions to identify genomic regions in genome-wide association studies. Asthma x air pollution interaction (2df) 606 Hispanic cases, 792 Hispanic controls, 643 European ancestry cases, 959 European ancestry controls NA NR [6212909] (imputed) 5 asthma, traffic air pollution measurement http://www.ebi.ac.uk/efo/EFO_0000270, http://www.ebi.ac.uk/efo/EFO_0007908 GCST009435 Genome-wide genotyping array 3000 2020-01-15 30456811 Moss LC 2018-11-19 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30456811 Using Bayes model averaging to leverage both gene main effects and G ×  E interactions to identify genomic regions in genome-wide association studies. Asthma x Hispanic interaction (2df) 606 Hispanic cases, 792 Hispanic controls, 643 European ancestry cases, 959 European ancestry controls NA NR [6212909] (imputed) 4 Hispanic or Latin American, asthma http://purl.obolibrary.org/obo/HANCESTRO_0014, http://www.ebi.ac.uk/efo/EFO_0000270 GCST009434 Genome-wide genotyping array 3000 2020-01-28 31727947 Hoglund J 2019-11-14 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31727947 Improved power and precision with whole genome sequencing data in genome-wide association studies of inflammatory biomarkers. Inflammatory biomarkers up to 957 Swedish ancestry individuals NA Illumina [12210410] 0 inflammatory biomarker measurement http://www.ebi.ac.uk/efo/EFO_0004872 GCST009522 Genome-wide sequencing 957 2020-02-21 31935283 Du Z 2020-01-01 Blood Adv www.ncbi.nlm.nih.gov/pubmed/31935283 A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry. Multiple myeloma 1,813 African American and African ancestry cases, 8,871 African American and African ancestry controls NA Illumina [12683648] (imputed) 10 multiple myeloma http://www.ebi.ac.uk/efo/EFO_0001378 GCST009680 Genome-wide genotyping array 10684 2020-10-08 31928498 Lind L 2020-01-13 Metab Syndr Relat Disord www.ncbi.nlm.nih.gov/pubmed/31928498 Genetic Determinants of Clustering of Cardiometabolic Risk Factors in U.K. Biobank. Systolic blood pressure 291,107 British ancestry individuals NA Affymetrix [9463307] (imputed) 18 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST010662 Genome-wide genotyping array 291107 2020-10-08 31928498 Lind L 2020-01-13 Metab Syndr Relat Disord www.ncbi.nlm.nih.gov/pubmed/31928498 Genetic Determinants of Clustering of Cardiometabolic Risk Factors in U.K. Biobank. Blood glucose levels 291,107 British ancestry individuals NA Affymetrix [9463307] (imputed) 17 glucose measurement http://www.ebi.ac.uk/efo/EFO_0004468 GCST010661 Genome-wide genotyping array 291107 2020-10-08 31928498 Lind L 2020-01-13 Metab Syndr Relat Disord www.ncbi.nlm.nih.gov/pubmed/31928498 Genetic Determinants of Clustering of Cardiometabolic Risk Factors in U.K. Biobank. Triglyceride levels 291,107 British ancestry individuals NA Affymetrix [9463307] (imputed) 22 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST010660 Genome-wide genotyping array 291107 2020-10-08 31928498 Lind L 2020-01-13 Metab Syndr Relat Disord www.ncbi.nlm.nih.gov/pubmed/31928498 Genetic Determinants of Clustering of Cardiometabolic Risk Factors in U.K. Biobank. Waist circumference 291,107 British ancestry individuals NA Affymetrix [9463307] (imputed) 23 waist circumference http://www.ebi.ac.uk/efo/EFO_0004342 GCST010659 Genome-wide genotyping array 291107 2020-10-08 31928498 Lind L 2020-01-13 Metab Syndr Relat Disord www.ncbi.nlm.nih.gov/pubmed/31928498 Genetic Determinants of Clustering of Cardiometabolic Risk Factors in U.K. Biobank. High density lipoprotein cholesterol levels 291,107 British ancestry individuals NA Affymetrix [9463307] (imputed) 22 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST010658 Genome-wide genotyping array 291107 2020-03-23 31888606 Zhang S 2019-12-30 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/31888606 Region-based interaction detection in genome-wide case-control studies. Renal complication in type 2 diabetes 882 East Asian ancestry cases, 2,231 East Asian ancestry controls NA NR [1257031] 0 renal system measurement http://www.ebi.ac.uk/efo/EFO_0004742 GCST009778 Genome-wide genotyping array 3113 2020-03-23 31888606 Zhang S 2019-12-30 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/31888606 Region-based interaction detection in genome-wide case-control studies. Myocardial infarction 2,967 cases, 3075 controls NA NR [649370] 4 myocardial infarction http://www.ebi.ac.uk/efo/EFO_0000612 GCST009779 Genome-wide genotyping array 6042 2020-04-17 32019797 Wojcik GL 2020-02-04 mBio www.ncbi.nlm.nih.gov/pubmed/32019797 Genome-Wide Association Study of Cryptosporidiosis in Infants Implicates PRKCA. Cryptosporidiosis 183 Bangladeshi ancestry cases, 873 Bangladeshi ancestry controls NA Illumina [6504706] (imputed) 3 cryptosporidiosis http://purl.obolibrary.org/obo/MONDO_0015474 GCST009861 Genome-wide genotyping array 1056 2019-08-01 31235808 Shungin D 2019-06-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31235808 Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data. Number of decayed, missing and filled tooth surfaces or use of dentures 14,976 European ancestry individuals with decayed, missing or filled tooth surface measurement, 11,816 Hispanic/Latino individuals with decayed, missing or filled tooth surface measurement, 77,714 European ancestry dentures cases, 383,317 European ancestry controls NA Affymetrix, Illumina [~ 8900000] (imputed) 47 dental caries, dentures http://www.ebi.ac.uk/efo/EFO_0003819, http://www.ebi.ac.uk/efo/EFO_0010078 GCST008295 Genome-wide genotyping array 487823 2019-08-01 31235808 Shungin D 2019-06-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31235808 Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data. Number of decayed, missing and filled tooth surfaces 14,976 European ancestry individuals, 11,816 Hispanic/Latino individuals NA Affymetrix, Illumina [at least 8900000] (imputed) 2 dental caries http://www.ebi.ac.uk/efo/EFO_0003819 GCST008302 Genome-wide genotyping array 26792 2019-08-01 31235808 Shungin D 2019-06-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31235808 Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data. Number of decayed and filled tooth surfaces per available tooth surface 14,717 European ancestry individuals, 11,816 Hispanic/Latino individuals NA Affymetrix, Illumina [at least 8900000] (imputed) 0 dental caries http://www.ebi.ac.uk/efo/EFO_0003819 GCST008299 Genome-wide genotyping array 26533 2019-08-01 31235808 Shungin D 2019-06-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31235808 Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data. Periodontitis 17,353 European and Hispanic/Latino ancestry cases, 28,210 European and Hispanic/Latino ancestry controls, 1,680 Japanese ancestry cases, 15,670 Japanese ancestry controls NA Affymetrix, Illumina [at least 8900000] (imputed) 0 periodontitis http://www.ebi.ac.uk/efo/EFO_0000649 GCST008300 Genome-wide genotyping array 62913 2019-08-01 31235808 Shungin D 2019-06-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31235808 Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data. Bleeding gums 60,210 European ancestry cases, 400,821 European ancestry controls NA Affymetrix [at least 8900000] (imputed) 0 Gingival bleeding http://purl.obolibrary.org/obo/HP_0000225 GCST008301 Genome-wide genotyping array 461031 2019-08-01 31235808 Shungin D 2019-06-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31235808 Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data. Painful gums 13,311 European ancestry cases, 447,720 European ancestry controls NA Affymetrix [at least 8900000] (imputed) 0 periodontal measurement http://www.ebi.ac.uk/efo/EFO_0007780 GCST008303 Genome-wide genotyping array 461031 2019-08-01 31235808 Shungin D 2019-06-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31235808 Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data. Dentures 77,714 European ancestry cases, 383,317 European ancestry controls NA Affymetrix [at least 8900000] (imputed) 47 dentures http://www.ebi.ac.uk/efo/EFO_0010078 GCST008306 Genome-wide genotyping array 461031 2019-08-01 31235808 Shungin D 2019-06-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31235808 Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data. Toothache 18,959 European ancestry cases, 442,072 European ancestry controls NA Affymetrix [at least 8900000] (imputed) 0 toothache http://www.ebi.ac.uk/efo/EFO_0010072 GCST008305 Genome-wide genotyping array 461031 2019-08-01 31235808 Shungin D 2019-06-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31235808 Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data. Mouth ulcers 47,091 European ancestry cases, 413,940 European ancestry controls NA Affymetrix [at least 8900000] (imputed) 0 Oral ulcer http://purl.obolibrary.org/obo/HP_0000155 GCST008304 Genome-wide genotyping array 461031 2019-08-01 31235808 Shungin D 2019-06-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31235808 Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data. Number of natural teeth 16,133 European ancestry individuals, 11,816 hispanic/Latino individuals NA Affymetrix, Illumina [at least 8900000] (imputed) 0 number of teeth measurement http://www.ebi.ac.uk/efo/EFO_0010073 GCST008298 Genome-wide genotyping array 27949 2019-08-01 31235808 Shungin D 2019-06-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31235808 Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data. Loose teeth 18,979 European ancestry cases, 442,052 European ancestry controls NA Affymetrix, Illumina [at least 8900000] (imputed) 0 periodontal measurement http://www.ebi.ac.uk/efo/EFO_0007780 GCST008297 Genome-wide genotyping array 461031 2019-08-01 31235808 Shungin D 2019-06-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31235808 Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data. Periodontitis or loose teeth 17,353 European and Hispanic/Latino ancestry periodontitis cases, 18,979 European ancestry loose teeth cases, 470,262 European and Hispanic/latino ancestry controls NA Affymetrix, Illumina [~ 8900000] (imputed) 0 periodontitis, periodontal measurement http://www.ebi.ac.uk/efo/EFO_0000649, http://www.ebi.ac.uk/efo/EFO_0007780 GCST008296 Genome-wide genotyping array 506594 2019-09-12 31462767 Sun Y 2019-08-28 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/31462767 Identification of novel risk loci with shared effects on alcoholism, heroin, and methamphetamine dependence. Alcohol dependence or heroin dependence or methamphetamine dependence 521 Han Chinese ancestry alcohol dependence cases, 1,026 Han Chinese ancestry heroin dependence cases, 1,749 Han Chinese ancestry methamphetamine dependence cases, 2,859 Han Chinese ancestry controls 146 Han Chinese ancestry alcohol dependence cases, 1,045 Han Chinese ancestry heroin dependence cases, 763 Han Chinese ancestry methamphetamine dependence cases, 1,904 Han Chinese ancestry controls Illumina [383065] (imputed) 3 alcohol dependence, heroin dependence, methamphetamine dependence http://www.ebi.ac.uk/efo/EFO_0003829, http://www.ebi.ac.uk/efo/EFO_0004240, http://www.ebi.ac.uk/efo/EFO_0004701 GCST008645 Genome-wide genotyping array 6155 2019-09-23 31466081 Luo A 2019-08-29 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/31466081 Epigenetic aging is accelerated in alcohol use disorder and regulated by genetic variation in APOL2. Epigenetic age acceleration in alcohol use disorder 154 European ancestry individuals, 156 African American individuals NA Illumina [up to 666531] 11 aging http://purl.obolibrary.org/obo/GO_0007568 GCST008748 Genome-wide genotyping array 310 2019-03-19 30531953 International League Against Epilepsy Consortium on Complex Epilepsies 2018-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30531953 Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies. Epilepsy 14,534 European ancestry cases, 531 Han Chinese ancestry cases, 147 African American cases, 24,218 European ancestry controls, 2,875 Han Chinese ancestry controls, 2,584 African American controls NA Affymetrix, Illumina [~ 5000000] (imputed) 3 epilepsy http://www.ebi.ac.uk/efo/EFO_0000474 GCST007343 Genome-wide genotyping array 44889 2019-03-19 30531953 International League Against Epilepsy Consortium on Complex Epilepsies 2018-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30531953 Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies. Childhood absence epilepsy 778 European ancestry cases, 24,218 European ancestry controls NA Affymetrix, Illumina [~ 5000000] (imputed) 2 Childhood absence epilepsy http://www.orpha.net/ORDO/Orphanet_64280 GCST007345 Genome-wide genotyping array 24996 2019-03-19 30531953 International League Against Epilepsy Consortium on Complex Epilepsies 2018-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30531953 Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies. Juvenile absence epilepsy 415 European ancestry cases, 24,218 European ancestry controls NA Affymetrix, Illumina [~ 5000000] (imputed) 0 Juvenile absence epilepsy http://www.orpha.net/ORDO/Orphanet_1941 GCST007346 Genome-wide genotyping array 24633 2019-03-19 30531953 International League Against Epilepsy Consortium on Complex Epilepsies 2018-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30531953 Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies. Juvenile myoclonic epilepsy 1,177 European ancestry cases, 4,218 European ancestry controls NA Affymetrix, Illumina [~ 5000000] (imputed) 1 Juvenile myoclonic epilepsy http://www.orpha.net/ORDO/Orphanet_307 GCST007347 Genome-wide genotyping array 5395 2019-03-19 30531953 International League Against Epilepsy Consortium on Complex Epilepsies 2018-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30531953 Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies. Epilepsy (generalized, with tonic-clonic seizures alone) 225 European ancestry cases, 24,218 European ancestry controls NA Affymetrix, Illumina [~ 5000000] (imputed) 0 epilepsy with generalized tonic-clonic seizures http://www.ebi.ac.uk/efo/EFO_0007262 GCST007348 Genome-wide genotyping array 24443 2019-03-19 30531953 International League Against Epilepsy Consortium on Complex Epilepsies 2018-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30531953 Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies. Focal epilepsy (lesion negative) 2,660 European ancestry cases, 24,218 European ancestry controls NA Affymetrix, Illumina [~ 5000000] (imputed) 0 partial epilepsy http://www.ebi.ac.uk/efo/EFO_0004263 GCST007349 Genome-wide genotyping array 26878 2019-03-19 30531953 International League Against Epilepsy Consortium on Complex Epilepsies 2018-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30531953 Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies. Focal epilepsy (with hippocampal sclerosis) 709 European ancestry cases, 24,218 European ancestry controls NA Affymetrix, Illumina [~ 5000000] (imputed) 2 partial epilepsy http://www.ebi.ac.uk/efo/EFO_0004263 GCST007350 Genome-wide genotyping array 24927 2019-03-19 30531953 International League Against Epilepsy Consortium on Complex Epilepsies 2018-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30531953 Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies. Focal epilepsy (with lesion other than hippocampal sclerosis) 2,751 European ancestry cases, 24,218 European ancestry controls NA Affymetrix, Illumina [~ 5000000] (imputed) 0 partial epilepsy http://www.ebi.ac.uk/efo/EFO_0004263 GCST007351 Genome-wide genotyping array 26969 2019-03-19 30531953 International League Against Epilepsy Consortium on Complex Epilepsies 2018-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30531953 Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies. Focal epilepsy 9,095 European ancestry cases, 490 Han Chinese ancestry cases, 86 African American cases, 24,218 European ancestry controls, 2,875 Han Chinese ancestry controls, 2,584 African American controls NA Affymetrix, Illumina [~ 5000000] (imputed) 1 partial epilepsy http://www.ebi.ac.uk/efo/EFO_0004263 GCST007352 Genome-wide genotyping array 39348 2019-03-19 30531953 International League Against Epilepsy Consortium on Complex Epilepsies 2018-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30531953 Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies. Generalized epilepsy 3,708 European ancestry cases, 61 African American cases, 24,218 European ancestry controls, 2,584 African American controls NA Affymetrix, Illumina [~ 5000000] (imputed) 11 generalised epilepsy http://www.ebi.ac.uk/efo/EFO_0005917 GCST007353 Genome-wide genotyping array 30571 2019-03-06 30583557 Loohuis LM 2018-12-22 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/30583557 The Alkaline Phosphatase (ALPL) Locus Is Associated with B6 Vitamer Levels in CSF and Plasma. B6 vitamer levels (multivariate analysis) 493 European ancestry individuals NA Illumina [6260487] (imputed) 3 vitamin B6 measurement http://www.ebi.ac.uk/efo/EFO_0004621 GCST007260 Genome-wide genotyping array 493 2019-03-06 30583557 Loohuis LM 2018-12-22 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/30583557 The Alkaline Phosphatase (ALPL) Locus Is Associated with B6 Vitamer Levels in CSF and Plasma. Cerebrospinal fluid pyridoxal phosphate levels 493 Dutch ancestry individuals NA Illumina [6260487] (imputed) 1 vitamin B6 measurement http://www.ebi.ac.uk/efo/EFO_0004621 GCST007261 Genome-wide genotyping array 493 2019-03-06 30583557 Loohuis LM 2018-12-22 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/30583557 The Alkaline Phosphatase (ALPL) Locus Is Associated with B6 Vitamer Levels in CSF and Plasma. Plasma pyridoxal phosphate levels 493 Dutch ancestry individuals NA Illumina [6260487] (imputed) 1 vitamin B6 measurement http://www.ebi.ac.uk/efo/EFO_0004621 GCST007262 Genome-wide genotyping array 493 2019-03-06 30583557 Loohuis LM 2018-12-22 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/30583557 The Alkaline Phosphatase (ALPL) Locus Is Associated with B6 Vitamer Levels in CSF and Plasma. Cerebrospinal fluid pyridoxal phosphate to pyridoxal ratio 493 Dutch ancestry individuals NA Illumina [6260487] (imputed) 1 vitamin B6 measurement http://www.ebi.ac.uk/efo/EFO_0004621 GCST007263 Genome-wide genotyping array 493 2019-03-06 30583557 Loohuis LM 2018-12-22 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/30583557 The Alkaline Phosphatase (ALPL) Locus Is Associated with B6 Vitamer Levels in CSF and Plasma. Plasma pyridoxal phosphate to pyridoxal ratio 493 Dutch ancestry individuals NA Illumina [6260487] (imputed) 1 vitamin B6 measurement http://www.ebi.ac.uk/efo/EFO_0004621 GCST007264 Genome-wide genotyping array 493 2019-03-06 30583557 Loohuis LM 2018-12-22 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/30583557 The Alkaline Phosphatase (ALPL) Locus Is Associated with B6 Vitamer Levels in CSF and Plasma. Plasma pyridoxic acid to pyridoxal phosphate ratio 493 Dutch ancestry individuals NA Illumina [6260487] (imputed) 1 vitamin B6 measurement http://www.ebi.ac.uk/efo/EFO_0004621 GCST007265 Genome-wide genotyping array 493 2019-09-04 31393916 Andaleon A 2019-08-08 PLoS One www.ncbi.nlm.nih.gov/pubmed/31393916 Genetically regulated gene expression underlies lipid traits in Hispanic cohorts. High density lipoprotein cholesterol levels 11,103 Hispanic or Latin American ancestry individuals NA Illumina [1770809] (imputed) 7 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST008592 Genome-wide genotyping array 11103 2019-09-04 31393916 Andaleon A 2019-08-08 PLoS One www.ncbi.nlm.nih.gov/pubmed/31393916 Genetically regulated gene expression underlies lipid traits in Hispanic cohorts. Triglyceride levels 11,103 Hispanic or Latin American ancestry individuals NA Illumina [1770809] (imputed) 0 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST008591 Genome-wide genotyping array 11103 2019-09-04 31393916 Andaleon A 2019-08-08 PLoS One www.ncbi.nlm.nih.gov/pubmed/31393916 Genetically regulated gene expression underlies lipid traits in Hispanic cohorts. Low density lipoprotein cholesterol levels 11,103 Hispanic or Latin American ancestry individuals NA Illumina [1770809] (imputed) 10 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST008593 Genome-wide genotyping array 11103 2019-09-04 31393916 Andaleon A 2019-08-08 PLoS One www.ncbi.nlm.nih.gov/pubmed/31393916 Genetically regulated gene expression underlies lipid traits in Hispanic cohorts. Total cholesterol levels 11,103 Hispanic or Latin American ancestry individuals NA Illumina [1770809] (imputed) 12 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST008594 Genome-wide genotyping array 11103 2019-12-18 31502714 Wang J 2019-09-10 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31502714 Genome-wide association study of circulating folate one-carbon metabolites. Blood metabolite levels 1,788 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 4 blood metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005664 GCST009318 Genome-wide genotyping array 1788 2019-01-29 30531825 Morgan MD 2018-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30531825 Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability. Red vs. brown/black hair color 15,731 British ancestry red hair individuals, 283,920 British ancestry brown or black hair individuals NA Affymetrix [9154080] (imputed) 40 hair color http://www.ebi.ac.uk/efo/EFO_0003924 GCST006986 Genome-wide genotyping array 299651 2019-01-30 30531825 Morgan MD 2018-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30531825 Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability. Blond vs. brown/black hair color 39,397 British ancestry blond hair individuals, 283,920 British ancestry brown or black hair individuals NA Affymetrix [9154080] (imputed) 213 hair color http://www.ebi.ac.uk/efo/EFO_0003924 GCST006988 Genome-wide genotyping array 323317 2019-01-30 30531825 Morgan MD 2018-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30531825 Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability. Brown vs. black hair color 269,394 British ancestry brown hair individuals, 14,526 British ancestry black hair individuals NA Affymetrix [9154080] (imputed) 56 hair color http://www.ebi.ac.uk/efo/EFO_0003924 GCST006989 Genome-wide genotyping array 283920 2020-01-13 31645637 Nagtegaal AP 2019-10-23 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31645637 Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment. Age-related hearing impairment (high minus low frequency) 9,675 European ancestry individuals 3,319 European ancestry individuals, 6,909 Hispanic individuals, 735 African American individuals Affymetrix, Illumina [NR] (imputed) 1 age-related hearing impairment http://www.ebi.ac.uk/efo/EFO_0005782 GCST009431 Genome-wide genotyping array 9675 2020-01-13 31645637 Nagtegaal AP 2019-10-23 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31645637 Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment. Age-related hearing impairment 9,675 European ancestry individuals 3,319 European ancestry individuals, 6,909 Hispanic individuals, 735 African American individuals Affymetrix, Illumina [NR] (imputed) 2 age-related hearing impairment http://www.ebi.ac.uk/efo/EFO_0005782 GCST009430 Genome-wide genotyping array 9675 2020-01-13 31645637 Nagtegaal AP 2019-10-23 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31645637 Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment. Age-related hearing impairment (low/mid frequency) 9,675 European ancestry individuals 3,319 European ancestry individuals, 6,909 Hispanic individuals, 735 African American individuals Affymetrix, Illumina [NR] (imputed) 6 age-related hearing impairment http://www.ebi.ac.uk/efo/EFO_0005782 GCST009432 Genome-wide genotyping array 9675 2020-01-13 31645637 Nagtegaal AP 2019-10-23 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31645637 Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment. Age-related hearing impairment (high frequency) 9,675 European ancestry individuals 3,319 European ancestry individuals, 6,909 Hispanic individuals, 735 African American individuals Affymetrix, Illumina [NR] (imputed) 6 age-related hearing impairment http://www.ebi.ac.uk/efo/EFO_0005782 GCST009429 Genome-wide genotyping array 9675 2019-11-19 29904099 Kottyan LC 2018-06-08 Genes Immun www.ncbi.nlm.nih.gov/pubmed/29904099 Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis. Eosinophilic esophagitis 1,210 European ancestry cases, 3,734 European ancestry controls NA Illumina [79405] 4 eosinophilic esophagitis http://www.ebi.ac.uk/efo/EFO_0004232 GCST009070 Targeted genotyping array [ImmunoChip] 4944 2019-12-11 31719529 Lyons PA 2019-11-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31719529 Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status. Eosinophilic granulomatosis with polyangiitis (MPO-ANCA positive) 159 European ancestry cases, 6,688 European ancestry controls 43 European and unknown ancestry cases, 121 European and unknown ancestry controls Affymetrix [9246221] (imputed) 2 Churg-Strauss syndrome http://www.ebi.ac.uk/efo/EFO_0007208 GCST009248 Genome-wide genotyping array 6847 2019-12-11 31719529 Lyons PA 2019-11-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31719529 Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status. Eosinophilic granulomatosis with polyangiitis (ANCA negative) 352 European ancestry cases, 6,688 European ancestry controls 94 European and unknown ancestry cases, 121 European and unknown ancestry controls Affymetrix [9246221] (imputed) 2 Churg-Strauss syndrome http://www.ebi.ac.uk/efo/EFO_0007208 GCST009249 Genome-wide genotyping array 7040 2019-12-11 31719529 Lyons PA 2019-11-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31719529 Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status. Eosinophilic granulomatosis with polyangiitis 534 European ancestry cases, 6,688 European ancestry controls 142 European and unknown ancestry cases, 121 European and unknown ancestry controls Affymetrix [9246221] (imputed) 4 Churg-Strauss syndrome http://www.ebi.ac.uk/efo/EFO_0007208 GCST009250 Genome-wide genotyping array 7222 2019-08-21 31285632 Klarin D 2019-07-08 Nat Med www.ncbi.nlm.nih.gov/pubmed/31285632 Genome-wide association study of peripheral artery disease in the Million Veteran Program. Peripheral artery disease 24,009 European ancestry cases, 150,983 European ancestry controls, 5,373 African ancestry cases, 42,485 African ancestry controls, 1,925 Hispanic cases, 18,285 Hispanic controls 5,117 European ancestry cases, 389,291 European ancestry controls Affymetrix [at least 20323458] (imputed) 20 peripheral arterial disease http://www.ebi.ac.uk/efo/EFO_0004265 GCST008474 Genome-wide genotyping array 243060 2019-08-21 31285632 Klarin D 2019-07-08 Nat Med www.ncbi.nlm.nih.gov/pubmed/31285632 Genome-wide association study of peripheral artery disease in the Million Veteran Program. Minimum ankle–brachial index 13,382 European ancestry individuals, 3,284 African ancestry individuals, 998 Hispanic individuals NA Affymetrix [at least 9211766] (imputed) 2 ankle brachial index http://www.ebi.ac.uk/efo/EFO_0003912 GCST008475 Genome-wide genotyping array 17664 2019-08-01 31299468 Condreay LD 2019-06-29 Respir Med www.ncbi.nlm.nih.gov/pubmed/31299468 Genetic effects on efficacy to fluticasone propionate/salmeterol treatment in COPD. Change in quality of life in response to fluticasone propionate/salmeterol in chronic obstructive pulmonary disease up to 1,209 European ancestry individuals, up to 136 African, African American, South East Asian, East Asian, American Indian/Alaskan Native, Mixed race, Arabic/North African, Central/South Asian or Japanese Asian ancestry individuals NA Affymetrix [> 10000000] (imputed) 1 response to corticosteroid, response to salmeterol, respiratory symptom change measurement http://purl.obolibrary.org/obo/GO_0031960, http://www.ebi.ac.uk/efo/EFO_0010062, http://www.ebi.ac.uk/efo/EFO_0010068 GCST008292 Genome-wide genotyping array 1345 2019-08-01 31299468 Condreay LD 2019-06-29 Respir Med www.ncbi.nlm.nih.gov/pubmed/31299468 Genetic effects on efficacy to fluticasone propionate/salmeterol treatment in COPD. Response to fluticasone propionate/salmeterol in chronic obstructive pulmonary disease 530 European, African, African American, South East Asian, East Asian, American Indian/Alaskan Native, Mixed race, Arabic/North African, Central/South Asian or Japanese Asian ancestry treated cases, 658 European, African, African American, South East Asian, East Asian, American Indian/Alaskan Native, Mixed race, Arabic/North African, Central/South Asian or Japanese Asian ancestry untreated cases NA Affymetrix [> 10000000] (imputed) 1 respiratory symptom measurement, response to corticosteroid, response to salmeterol http://www.ebi.ac.uk/efo/EFO_0007939, http://purl.obolibrary.org/obo/GO_0031960, http://www.ebi.ac.uk/efo/EFO_0010062 GCST008294 Genome-wide genotyping array 1188 2019-08-01 31299468 Condreay LD 2019-06-29 Respir Med www.ncbi.nlm.nih.gov/pubmed/31299468 Genetic effects on efficacy to fluticasone propionate/salmeterol treatment in COPD. Change in trough FEV1 in response to fluticasone propionate/salmeterol in chronic obstructive pulmonary disease 1,869 European ancestry individuals, 55 African American or African ancestry individuals, 33 South East Asian ancestry individuals, 33 East Asian ancestry individuals, 7 American Indian/Alaskan Native ancestry individuals, 4 Mixed race individuals, 3 Arabic/North African ancestry individuals, 1 Central/South Asian ancestry individuals NA Affymetrix [> 10000000] (imputed) 0 FEV change measurement, response to corticosteroid, response to salmeterol http://www.ebi.ac.uk/efo/EFO_0005921, http://purl.obolibrary.org/obo/GO_0031960, http://www.ebi.ac.uk/efo/EFO_0010062 GCST008293 Genome-wide genotyping array 2005 2019-09-24 31296530 Trendowski MR 2019-07-11 Clin Cancer Res www.ncbi.nlm.nih.gov/pubmed/31296530 Clinical and Genome-Wide Analysis of Serum Platinum Levels after Cisplatin-Based Chemotherapy. Serum platinum levels after completion of cisplatin chemotherapy 866 European ancestry individuals, 17 non-European ancestry individuals, 127 individuals NR Illumina [7305641] (imputed) 33 response to cisplatin, platinum measurement http://purl.obolibrary.org/obo/GO_0072718, http://www.ebi.ac.uk/efo/EFO_0010154 GCST008756 Genome-wide genotyping array 1010 2019-08-27 31295725 Wang ZT 2019-07-11 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/31295725 Genome-wide association study identifies CD1A associated with rate of increase in plasma neurofilament light in non-demented elders. Change in neurofilament light levels 545 European ancestry individuals NA Illumina [1231747] 5 neurofilament light chain measurement http://www.ebi.ac.uk/efo/EFO_0009178 GCST008497 Genome-wide genotyping array 545 2019-08-01 31209788 Li HQ 2019-06-18 Neurotox Res www.ncbi.nlm.nih.gov/pubmed/31209788 Genome-Wide Association Study of Cerebral Microbleeds on MRI. Cerebral microbleed progression 57 European ancestry cases, 95 European ancestry controls NA Illumina [979539] 1 cerebral microbleeds, disease progression measurement http://www.ebi.ac.uk/efo/EFO_0010059, http://www.ebi.ac.uk/efo/EFO_0008336 GCST008274 Genome-wide genotyping array 152 2019-08-01 31209788 Li HQ 2019-06-18 Neurotox Res www.ncbi.nlm.nih.gov/pubmed/31209788 Genome-Wide Association Study of Cerebral Microbleeds on MRI. Cerebral microbleeds 176 European ancestry cases, 278 European ancestry controls NA Illumina [983392] 6 cerebral microbleeds http://www.ebi.ac.uk/efo/EFO_0010059 GCST008275 Genome-wide genotyping array 454 2019-07-19 31194736 Tiensuu H 2019-06-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31194736 Risk of spontaneous preterm birth and fetal growth associates with fetal SLIT2. Gestational age at birth (child effect) 666 Finnish ancestry infants NA Illumina [6778521] (imputed) 9 gestational age http://www.ebi.ac.uk/efo/EFO_0005112 GCST008176 Genome-wide genotyping array 666 2019-07-19 31194736 Tiensuu H 2019-06-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31194736 Risk of spontaneous preterm birth and fetal growth associates with fetal SLIT2. Spontaneous preterm birth (preterm birth) 247 Finnish ancestry infant cases, 419 Finnish ancestry infant controls NA Illumina [6778521] (imputed) 19 spontaneous preterm birth http://www.ebi.ac.uk/efo/EFO_0006917 GCST008177 Genome-wide genotyping array 666 2019-07-19 31194736 Tiensuu H 2019-06-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31194736 Risk of spontaneous preterm birth and fetal growth associates with fetal SLIT2. Early spontaneous preterm birth 172 Finnish ancestry infant cases, 419 Finnish ancestry infant controls NA Illumina [6778521] (imputed) 13 spontaneous preterm birth http://www.ebi.ac.uk/efo/EFO_0006917 GCST008178 Genome-wide genotyping array 591 2019-07-19 31194736 Tiensuu H 2019-06-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31194736 Risk of spontaneous preterm birth and fetal growth associates with fetal SLIT2. Moderate-to-late spontaneous preterm birth 75 Finnish ancestry infant cases, 419 Finnish ancestry infant controls NA Illumina [6778521] (imputed) 24 spontaneous preterm birth http://www.ebi.ac.uk/efo/EFO_0006917 GCST008179 Genome-wide genotyping array 494 2019-07-19 31194736 Tiensuu H 2019-06-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31194736 Risk of spontaneous preterm birth and fetal growth associates with fetal SLIT2. Spontaneous preterm birth with premature rupture of membranes 133 Finnish ancestry infant cases, 419 Finnish ancestry infant controls NA Illumina [6778521] (imputed) 18 preterm premature rupture of the membranes, spontaneous preterm birth http://purl.obolibrary.org/obo/MONDO_0012511, http://www.ebi.ac.uk/efo/EFO_0006917 GCST008180 Genome-wide genotyping array 552 2019-07-19 31194736 Tiensuu H 2019-06-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31194736 Risk of spontaneous preterm birth and fetal growth associates with fetal SLIT2. Spontaneous preterm birth without premature rupture of membranes 101 Finnish ancestry infant cases, 419 Finnish ancestry infant controls NA Illumina [6778521] (imputed) 22 spontaneous preterm birth http://www.ebi.ac.uk/efo/EFO_0006917 GCST008181 Genome-wide genotyping array 520 2019-08-22 26398853 Ye BD 2016-01-01 Inflamm Bowel Dis www.ncbi.nlm.nih.gov/pubmed/26398853 Identification of Ten Additional Susceptibility Loci for Ulcerative Colitis Through Immunochip Analysis in Koreans. Ulcerative colitis 705 Korean ancestry cases, 1,178 Korean ancestry controls 980 Korean ancestry cases, 2,694 Korean ancestry controls Illumina [536821] (imputed) 5 ulcerative colitis http://www.ebi.ac.uk/efo/EFO_0000729 GCST008483 Targeted genotyping array [ImmunoChip] 1883 2019-08-01 31246245 Khawaja AP 2019-06-27 JAMA Ophthalmol www.ncbi.nlm.nih.gov/pubmed/31246245 Genetic Variants Associated With Corneal Biomechanical Properties and Potentially Conferring Susceptibility to Keratoconus in a Genome-Wide Association Study. Corneal resistance factor 6,645 individuals 2,384 European ancestry individuals Affymetrix [NR] (imputed) 8 corneal resistance factor http://www.ebi.ac.uk/efo/EFO_0010067 GCST008276 Genome-wide genotyping array 6645 2019-08-01 31246245 Khawaja AP 2019-06-27 JAMA Ophthalmol www.ncbi.nlm.nih.gov/pubmed/31246245 Genetic Variants Associated With Corneal Biomechanical Properties and Potentially Conferring Susceptibility to Keratoconus in a Genome-Wide Association Study. Corneal hysteresis 6,645 individuals 2,384 European ancestry individuals Affymetrix [NR] (imputed) 5 corneal hysteresis http://www.ebi.ac.uk/efo/EFO_0010066 GCST008277 Genome-wide genotyping array 6645 2020-01-27 31339356 Hobbs BD 2019-07-24 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/31339356 Overlap of Genetic Risk Between Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis. Subpleural-predominant interstitial lung abnormalities 965 European ancestry cases, 154 African American cases, 168 cases, 7,255 European ancestry controls, 1,717 African American controls, 450 controls NA Affymetrix, Illumina [at least 412049] (imputed) 6 interstitial lung disease http://www.ebi.ac.uk/efo/EFO_0004244 GCST009502 Genome-wide genotyping array 10709 2020-01-27 31339356 Hobbs BD 2019-07-24 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/31339356 Overlap of Genetic Risk Between Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis. Interstitial lung abnormalities 1,181 European ancestry cases, 280 African American cases, 54 Hispanic cases, 184 cases, 7,255 European ancestry controls, 2,184 African American controls, 385 Hispanic controls, 450 controls NA Affymetrix, Illumina [at least 412049] (imputed) 7 interstitial lung disease http://www.ebi.ac.uk/efo/EFO_0004244 GCST009501 Genome-wide genotyping array 11973 2019-12-16 31447353 Maciukiewicz M 2019-08-22 Schizophr Res www.ncbi.nlm.nih.gov/pubmed/31447353 Genome-wide association study on antipsychotic-induced weight gain in Europeans and African-Americans. Antipsychotic drug-induced weight gain in schizophrenia 144 European ancestry individuals, 57 African American individuals NA Illumina [1819374] (imputed) 18 antipsychotic drug related weight gain http://www.ebi.ac.uk/efo/EFO_0004567 GCST009302 Genome-wide genotyping array 201 2019-12-16 31447353 Maciukiewicz M 2019-08-22 Schizophr Res www.ncbi.nlm.nih.gov/pubmed/31447353 Genome-wide association study on antipsychotic-induced weight gain in Europeans and African-Americans. Antipsychotic drug-induced weight gain in schizophrenia or autism 269 European ancestry individuals NA Illumina [NR] (imputed) 1 antipsychotic drug related weight gain http://www.ebi.ac.uk/efo/EFO_0004567 GCST009301 Genome-wide genotyping array 269 2019-05-30 30995994 Truong DT 2019-04-17 J Med Genet www.ncbi.nlm.nih.gov/pubmed/30995994 Multivariate genome-wide association study of rapid automatised naming and rapid alternating stimulus in Hispanic American and African-American youth. Latent naming speed 441 African American children NA Illumina [1265623] 0 reading and spelling ability http://www.ebi.ac.uk/efo/EFO_0005301 GCST007862 Genome-wide genotyping array 441 2019-05-30 30995994 Truong DT 2019-04-17 J Med Genet www.ncbi.nlm.nih.gov/pubmed/30995994 Multivariate genome-wide association study of rapid automatised naming and rapid alternating stimulus in Hispanic American and African-American youth. Latent naming speed 883 Hispanic American children NA Illumina [1265623] 0 reading and spelling ability http://www.ebi.ac.uk/efo/EFO_0005301 GCST007861 Genome-wide genotyping array 883 2019-05-30 30995994 Truong DT 2019-04-17 J Med Genet www.ncbi.nlm.nih.gov/pubmed/30995994 Multivariate genome-wide association study of rapid automatised naming and rapid alternating stimulus in Hispanic American and African-American youth. Rapid automised naming and rapid alternating stimulus test performance 883 Hispanic American children, 441 African American children NA Illumina [1265623] 4 reading and spelling ability http://www.ebi.ac.uk/efo/EFO_0005301 GCST007859 Genome-wide genotyping array 1324 2019-05-30 30995994 Truong DT 2019-04-17 J Med Genet www.ncbi.nlm.nih.gov/pubmed/30995994 Multivariate genome-wide association study of rapid automatised naming and rapid alternating stimulus in Hispanic American and African-American youth. Latent naming speed 883 Hispanic American children, 441 African American children NA Illumina [1265623] 7 reading and spelling ability http://www.ebi.ac.uk/efo/EFO_0005301 GCST007860 Genome-wide genotyping array 1324 2019-05-30 30995994 Truong DT 2019-04-17 J Med Genet www.ncbi.nlm.nih.gov/pubmed/30995994 Multivariate genome-wide association study of rapid automatised naming and rapid alternating stimulus in Hispanic American and African-American youth. Rapid automised naming of objects 883 Hispanic American children, 441 African American children NA Illumina [1265623] 0 reading and spelling ability http://www.ebi.ac.uk/efo/EFO_0005301 GCST007865 Genome-wide genotyping array 1324 2019-05-30 30995994 Truong DT 2019-04-17 J Med Genet www.ncbi.nlm.nih.gov/pubmed/30995994 Multivariate genome-wide association study of rapid automatised naming and rapid alternating stimulus in Hispanic American and African-American youth. Rapid automised naming of letters 883 Hispanic American children, 441 African American children NA Illumina [1265623] 3 reading and spelling ability http://www.ebi.ac.uk/efo/EFO_0005301 GCST007864 Genome-wide genotyping array 1324 2019-05-30 30995994 Truong DT 2019-04-17 J Med Genet www.ncbi.nlm.nih.gov/pubmed/30995994 Multivariate genome-wide association study of rapid automatised naming and rapid alternating stimulus in Hispanic American and African-American youth. Rapid alternating stimulus test for letters/numbers 883 Hispanic American children, 441 African American children NA Illumina [1265623] 3 reading and spelling ability http://www.ebi.ac.uk/efo/EFO_0005301 GCST007863 Genome-wide genotyping array 1324 2019-08-06 29678681 Matana A 2018-04-18 Genomics www.ncbi.nlm.nih.gov/pubmed/29678681 Genome-wide meta-analysis identifies novel gender specific loci associated with thyroid antibodies level in Croatians. Plasma anti-thyroid peroxidase levels 1,593 Croatian ancestry women, 1,025 Croatian ancestry men NA Illumina [5527232] (imputed) 20 thyroid peroxidase antibody measurement http://www.ebi.ac.uk/efo/EFO_0005666 GCST008368 Genome-wide genotyping array 2618 2019-08-06 29678681 Matana A 2018-04-18 Genomics www.ncbi.nlm.nih.gov/pubmed/29678681 Genome-wide meta-analysis identifies novel gender specific loci associated with thyroid antibodies level in Croatians. Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) up to 1,596 Croatian ancestry women, up to 1,033 Croatian ancestry men NA Illumina [5527232] (imputed) 19 thyroid peroxidase antibody measurement, anti-thyroglobulin antibody measurement http://www.ebi.ac.uk/efo/EFO_0005666, http://www.ebi.ac.uk/efo/EFO_0009896 GCST008367 Genome-wide genotyping array 2629 2019-08-06 29678681 Matana A 2018-04-18 Genomics www.ncbi.nlm.nih.gov/pubmed/29678681 Genome-wide meta-analysis identifies novel gender specific loci associated with thyroid antibodies level in Croatians. Plasma anti-thyroglobulin levels 1,596 Croatian ancestry women, 1,033 Croatian ancestry men NA Illumina [5527232] (imputed) 24 anti-thyroglobulin antibody measurement http://www.ebi.ac.uk/efo/EFO_0009896 GCST008369 Genome-wide genotyping array 2629 2019-11-08 31469419 Manichaikul A 2019-08-30 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/31469419 Identification of novel epithelial ovarian cancer loci in Women of African Ancestry. Epithelial ovarian cancer 755 African ancestry cases, 1,235 African ancestry controls NA Illumina [12486624] (imputed) 4 Malignant epithelial tumor of ovary http://www.orpha.net/ORDO/Orphanet_398934 GCST009008 Genome-wide genotyping array 1990 2019-11-08 31469419 Manichaikul A 2019-08-30 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/31469419 Identification of novel epithelial ovarian cancer loci in Women of African Ancestry. High-grade serous ovarian cancer 537 African ancestry cases, 1,235 African ancestry controls NA Illumina [11083029] (imputed) 6 ovarian serous carcinoma http://www.ebi.ac.uk/efo/EFO_1001516 GCST009007 Genome-wide genotyping array 1772 2019-04-24 30593799 Vergara C 2018-12-26 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/30593799 Multi-Ancestry Genome-Wide Association Study of Spontaneous Clearance of Hepatitis C Virus. Hepatitis C (spontaneous viral clearance) 701 European ancestry cases, 1,035 European ancestry controls, 445 African American cases, 1,756 African American controls, 173 Hispanic ancestry cases, 313 Hispanic ancestry controls NA Illumina [15704341] (imputed) 3 remission, hepatitis C virus infection http://www.ebi.ac.uk/efo/EFO_0009785, http://www.ebi.ac.uk/efo/EFO_0003047 GCST007631 Genome-wide genotyping array 4423 2019-04-24 30593799 Vergara C 2018-12-26 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/30593799 Multi-Ancestry Genome-Wide Association Study of Spontaneous Clearance of Hepatitis C Virus. Hepatitis C (spontaneous viral clearance) 445 African American cases, 1,756 African American controls NA Illumina [at least 15383342] (imputed) 1 remission, hepatitis C virus infection http://www.ebi.ac.uk/efo/EFO_0009785, http://www.ebi.ac.uk/efo/EFO_0003047 GCST007632 Genome-wide genotyping array 2201 2019-04-24 30593799 Vergara C 2018-12-26 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/30593799 Multi-Ancestry Genome-Wide Association Study of Spontaneous Clearance of Hepatitis C Virus. Hepatitis C (spontaneous viral clearance) 701 European ancestry cases, 1,035 European ancestry controls NA Illumina [8968220] (imputed) 2 remission, hepatitis C virus infection http://www.ebi.ac.uk/efo/EFO_0009785, http://www.ebi.ac.uk/efo/EFO_0003047 GCST007633 Genome-wide genotyping array 1736 2019-04-24 30593799 Vergara C 2018-12-26 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/30593799 Multi-Ancestry Genome-Wide Association Study of Spontaneous Clearance of Hepatitis C Virus. Hepatitis C (spontaneous viral clearance) 173 Hispanic ancestry cases, 313 Hispanic ancestry controls NA Illumina [12650831] (imputed) 1 remission, hepatitis C virus infection http://www.ebi.ac.uk/efo/EFO_0009785, http://www.ebi.ac.uk/efo/EFO_0003047 GCST007634 Genome-wide genotyping array 486 2019-02-22 30578281 Williams LM 2018-12-01 Blood Adv www.ncbi.nlm.nih.gov/pubmed/30578281 A locus on chromosome 5 shows African ancestry-limited association with alloimmunization in sickle cell disease. Alloimmunization response to red blood cell transfusion in sickle cell anemia 144 African American cases, 123 African American controls 62 African American cases, 68 African American controls Illumina [1509415] 1 alloimmunization, response to red blood cell transfusion http://www.ebi.ac.uk/efo/EFO_0006804, http://www.ebi.ac.uk/efo/EFO_0006802 GCST007210 Genome-wide genotyping array 267 2019-08-23 30584014 Huang M 2018-12-12 Neuroimage Clin www.ncbi.nlm.nih.gov/pubmed/30584014 Spatial correlations exploitation based on nonlocal voxel-wise GWAS for biomarker detection of AD. Voxel-wise structural brain imaging measurements in Alzheimer’s disease 708 European ancestry individuals NA Illumina [501584] 14 neuroimaging measurement http://www.ebi.ac.uk/efo/EFO_0004346 GCST008491 Genome-wide genotyping array 708 2019-07-05 30698716 de Vries PS 2019-01-29 Am J Epidemiol www.ncbi.nlm.nih.gov/pubmed/30698716 Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. HDL cholesterol levels 89,893 European ancestry individuals, 20,989 African American individuals, 12,450 Asian ancestry individuals, 3,994 HIspanic individuals 136,986 European ancestry individuals, 4,475 African American or Afro-Caribbean individuals, 108,431 Asian ancestry individuals, 13,714 Hispanic individuals, 3,652 Brazilian ancestry individuals Affymetrix, Illumina [NR] (imputed) 141 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST008070 Genome-wide genotyping array 127326 2019-07-05 30698716 de Vries PS 2019-01-29 Am J Epidemiol www.ncbi.nlm.nih.gov/pubmed/30698716 Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. LDL cholesterol levels in current drinkers 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals 107,548 European ancestry individuals, 2,028 African American or Afro-Caribbean individuals, 41,240 Asian ancestry individuals, 6,622 Hispanic individuals, 1,984 Brazilian ancestry individuals Affymetrix, Illumina [NR] (imputed) 118 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST008086 Genome-wide genotyping array 71394 2019-07-05 30698716 de Vries PS 2019-01-29 Am J Epidemiol www.ncbi.nlm.nih.gov/pubmed/30698716 Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. HDL cholesterol levels in current drinkers 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals 107,548 European ancestry individuals, 2,028 African American or Afro-Caribbean individuals, 41,240 Asian ancestry individuals, 6,622 Hispanic individuals, 1,984 Brazilian ancestry individuals Affymetrix, Illumina [NR] (imputed) 190 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST008085 Genome-wide genotyping array 71394 2019-07-05 30698716 de Vries PS 2019-01-29 Am J Epidemiol www.ncbi.nlm.nih.gov/pubmed/30698716 Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. Triglyceride levels in current drinkers 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals 107,548 European ancestry individuals, 2,028 African American or Afro-Caribbean individuals, 41,240 Asian ancestry individuals, 6,622 Hispanic individuals, 1,984 Brazilian ancestry individuals Affymetrix, Illumina [NR] (imputed) 138 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST008087 Genome-wide genotyping array 71394 2019-07-05 30698716 de Vries PS 2019-01-29 Am J Epidemiol www.ncbi.nlm.nih.gov/pubmed/30698716 Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers 107,548 European ancestry current drinkers, 2,028 African American or Afro-Caribbean current drinkers, 41,240 Asian ancestry current drinkers, 6,622 Hispanic individuals, 1,984 Brazilian ancestry individuals, 29,438 European ancestry non-drinkers, 2,447 African American or Afro-Caribbean non-drinkers, 67,191 Asian ancestry non-drinkers, 7,092 Hispanic non-drinkers, 1,668 Brazilian ancestry non-drinkers Affymetrix, Illumina [NR] (imputed) 236 alcohol drinking, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004329, http://www.ebi.ac.uk/efo/EFO_0004612 GCST008084 Genome-wide genotyping array 127326 2019-07-05 30698716 de Vries PS 2019-01-29 Am J Epidemiol www.ncbi.nlm.nih.gov/pubmed/30698716 Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers 107,548 European ancestry current drinkers, 2,028 African American or Afro-Caribbean current drinkers, 41,240 Asian ancestry current drinkers, 6,622 Hispanic individuals, 1,984 Brazilian ancestry individuals, 29,438 European ancestry non-drinkers, 2,447 African American or Afro-Caribbean non-drinkers, 67,191 Asian ancestry non-drinkers, 7,092 Hispanic non-drinkers, 1,668 Brazilian ancestry non-drinkers Affymetrix, Illumina [NR] (imputed) 162 triglyceride measurement, alcohol drinking http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0004329 GCST008083 Genome-wide genotyping array 127326 2019-07-05 30698716 de Vries PS 2019-01-29 Am J Epidemiol www.ncbi.nlm.nih.gov/pubmed/30698716 Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (1df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers 107,548 European ancestry current drinkers, 2,028 African American or Afro-Caribbean current drinkers, 41,240 Asian ancestry current drinkers, 6,622 Hispanic individuals, 1,984 Brazilian ancestry individuals, 29,438 European ancestry non-drinkers, 2,447 African American or Afro-Caribbean non-drinkers, 67,191 Asian ancestry non-drinkers, 7,092 Hispanic non-drinkers, 1,668 Brazilian ancestry non-drinkers Affymetrix, Illumina [NR] (imputed) 0 low density lipoprotein cholesterol measurement, alcohol drinking http://www.ebi.ac.uk/efo/EFO_0004611, http://www.ebi.ac.uk/efo/EFO_0004329 GCST008082 Genome-wide genotyping array 127326 2019-07-05 30698716 de Vries PS 2019-01-29 Am J Epidemiol www.ncbi.nlm.nih.gov/pubmed/30698716 Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (1df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers 107,548 European ancestry current drinkers, 2,028 African American or Afro-Caribbean current drinkers, 41,240 Asian ancestry current drinkers, 6,622 Hispanic individuals, 1,984 Brazilian ancestry individuals, 29,438 European ancestry non-drinkers, 2,447 African American or Afro-Caribbean non-drinkers, 67,191 Asian ancestry non-drinkers, 7,092 Hispanic non-drinkers, 1,668 Brazilian ancestry non-drinkers Affymetrix, Illumina [NR] (imputed) 0 alcohol drinking, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004329, http://www.ebi.ac.uk/efo/EFO_0004612 GCST008081 Genome-wide genotyping array 127326 2019-07-05 30698716 de Vries PS 2019-01-29 Am J Epidemiol www.ncbi.nlm.nih.gov/pubmed/30698716 Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (1df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers 107,548 European ancestry current drinkers, 2,028 African American or Afro-Caribbean current drinkers, 41,240 Asian ancestry current drinkers, 6,622 Hispanic individuals, 1,984 Brazilian ancestry individuals, 29,438 European ancestry non-drinkers, 2,447 African American or Afro-Caribbean non-drinkers, 67,191 Asian ancestry non-drinkers, 7,092 Hispanic non-drinkers, 1,668 Brazilian ancestry non-drinkers Affymetrix, Illumina [NR] (imputed) 0 triglyceride measurement, alcohol drinking http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0004329 GCST008080 Genome-wide genotyping array 127326 2019-07-05 30698716 de Vries PS 2019-01-29 Am J Epidemiol www.ncbi.nlm.nih.gov/pubmed/30698716 Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers 107,548 European ancestry current drinkers, 2,028 African American or Afro-Caribbean current drinkers, 41,240 Asian ancestry current drinkers, 6,622 Hispanic individuals, 1,984 Brazilian ancestry individuals, 29,438 European ancestry non-drinkers, 2,447 African American or Afro-Caribbean non-drinkers, 67,191 Asian ancestry non-drinkers, 7,092 Hispanic non-drinkers, 1,668 Brazilian ancestry non-drinkers Affymetrix, Illumina [NR] (imputed) 162 low density lipoprotein cholesterol measurement, alcohol drinking http://www.ebi.ac.uk/efo/EFO_0004611, http://www.ebi.ac.uk/efo/EFO_0004329 GCST008079 Genome-wide genotyping array 127326 2019-07-05 30698716 de Vries PS 2019-01-29 Am J Epidemiol www.ncbi.nlm.nih.gov/pubmed/30698716 Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers 71,281 European ancestry regular drinkers, 711 African American or Afro-Caribbean regular drinkers, 35,088 Asian ancestry regular drinkers, 3,742 Hispanic regular drinkers, 36,267 European ancestry non-regular drinkers, 1,317 African American or Afro-Caribbean non-regular drinkers, 6,152 Asian ancestry non-regular drinkers, 2,880 Hispanic non-regular drinkers Affymetrix, Illumina [NR] (imputed) 153 low density lipoprotein cholesterol measurement, alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0004611, http://www.ebi.ac.uk/efo/EFO_0007878 GCST008078 Genome-wide genotyping array 71394 2019-07-05 30698716 de Vries PS 2019-01-29 Am J Epidemiol www.ncbi.nlm.nih.gov/pubmed/30698716 Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. LDL cholesterol levels 89,893 European ancestry individuals, 20,989 African American individuals, 12,450 Asian ancestry individuals, 3,994 HIspanic individuals 136,986 European ancestry individuals, 4,475 African American or Afro-Caribbean individuals, 108,431 Asian ancestry individuals, 13,714 Hispanic individuals, 3,652 Brazilian ancestry individuals Affymetrix, Illumina [NR] (imputed) 88 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST008077 Genome-wide genotyping array 127326 2019-07-05 30698716 de Vries PS 2019-01-29 Am J Epidemiol www.ncbi.nlm.nih.gov/pubmed/30698716 Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. Triglyceride levels 89,893 European ancestry individuals, 20,989 African American individuals, 12,450 Asian ancestry individuals, 3,994 HIspanic individuals 136,986 European ancestry individuals, 4,475 African American or Afro-Caribbean individuals, 108,431 Asian ancestry individuals, 13,714 Hispanic individuals, 3,652 Brazilian ancestry individuals Affymetrix, Illumina [NR] (imputed) 89 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST008076 Genome-wide genotyping array 127326 2019-07-05 30698716 de Vries PS 2019-01-29 Am J Epidemiol www.ncbi.nlm.nih.gov/pubmed/30698716 Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers 71,281 European ancestry regular drinkers, 711 African American or Afro-Caribbean regular drinkers, 35,088 Asian ancestry regular drinkers, 3,742 Hispanic regular drinkers, 36,267 European ancestry non-regular drinkers, 1,317 African American or Afro-Caribbean non-regular drinkers, 6,152 Asian ancestry non-regular drinkers, 2,880 Hispanic non-regular drinkers Affymetrix, Illumina [NR] (imputed) 226 alcohol consumption measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0007878, http://www.ebi.ac.uk/efo/EFO_0004612 GCST008075 Genome-wide genotyping array 71394 2019-07-05 30698716 de Vries PS 2019-01-29 Am J Epidemiol www.ncbi.nlm.nih.gov/pubmed/30698716 Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers 71,281 European ancestry regular drinkers, 711 African American or Afro-Caribbean regular drinkers, 35,088 Asian ancestry regular drinkers, 3,742 Hispanic regular drinkers, 36,267 European ancestry non-regular drinkers, 1,317 African American or Afro-Caribbean non-regular drinkers, 6,152 Asian ancestry non-regular drinkers, 2,880 Hispanic non-regular drinkers Affymetrix, Illumina [NR] (imputed) 162 triglyceride measurement, alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0007878 GCST008074 Genome-wide genotyping array 71394 2019-07-05 30698716 de Vries PS 2019-01-29 Am J Epidemiol www.ncbi.nlm.nih.gov/pubmed/30698716 Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (1df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers 71,281 European ancestry regular drinkers, 711 African American or Afro-Caribbean regular drinkers, 35,088 Asian ancestry regular drinkers, 3,742 Hispanic regular drinkers, 36,267 European ancestry non-regular drinkers, 1,317 African American or Afro-Caribbean non-regular drinkers, 6,152 Asian ancestry non-regular drinkers, 2,880 Hispanic non-regular drinkers Affymetrix, Illumina [NR] (imputed) 0 low density lipoprotein cholesterol measurement, alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0004611, http://www.ebi.ac.uk/efo/EFO_0007878 GCST008073 Genome-wide genotyping array 71394 2019-07-05 30698716 de Vries PS 2019-01-29 Am J Epidemiol www.ncbi.nlm.nih.gov/pubmed/30698716 Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (1df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers 71,281 European ancestry regular drinkers, 711 African American or Afro-Caribbean regular drinkers, 35,088 Asian ancestry regular drinkers, 3,742 Hispanic regular drinkers, 36,267 European ancestry non-regular drinkers, 1,317 African American or Afro-Caribbean non-regular drinkers, 6,152 Asian ancestry non-regular drinkers, 2,880 Hispanic non-regular drinkers Affymetrix, Illumina [NR] (imputed) 0 alcohol consumption measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0007878, http://www.ebi.ac.uk/efo/EFO_0004612 GCST008072 Genome-wide genotyping array 71394 2019-07-05 30698716 de Vries PS 2019-01-29 Am J Epidemiol www.ncbi.nlm.nih.gov/pubmed/30698716 Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (1df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers 71,281 European ancestry regular drinkers, 711 African American or Afro-Caribbean regular drinkers, 35,088 Asian ancestry regular drinkers, 3,742 Hispanic regular drinkers, 36,267 European ancestry non-regular drinkers, 1,317 African American or Afro-Caribbean non-regular drinkers, 6,152 Asian ancestry non-regular drinkers, 2,880 Hispanic non-regular drinkers Affymetrix, Illumina [NR] (imputed) 0 triglyceride measurement, alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0007878 GCST008071 Genome-wide genotyping array 71394 2020-11-24 31362389 Chen YC 2019-07-29 J Clin Med www.ncbi.nlm.nih.gov/pubmed/31362389 LRRTM4 and PCSK5 Genetic Polymorphisms as Markers for Cognitive Impairment in A Hypotensive Aging Population: A Genome-Wide Association Study in Taiwan. Hypotension and cognitive impairment 56 Han Chinese ancestry cases, 1,799 Han Chinese ancestry controls NA NR [590244] 3 hypotension, Cognitive impairment http://www.ebi.ac.uk/efo/EFO_0005251, http://purl.obolibrary.org/obo/HP_0100543 GCST010762 Genome-wide genotyping array 1855 2019-09-16 31482140 Meng W 2019-08-28 Commun Biol www.ncbi.nlm.nih.gov/pubmed/31482140 Genome-wide association study of knee pain identifies associations with GDF5 and COL27A1 in UK Biobank. Knee pain 22,204 British ancestry cases, 149,312 British ancestry controls NA Affymetrix [15377520] (imputed) 4 Knee pain http://purl.obolibrary.org/obo/HP_0030839 GCST008672 Genome-wide genotyping array 171516 2019-01-14 30124842 Yengo L 2018-08-16 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30124842 Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry. Body mass index 456,426 European ancestry individuals, 224,849 individuals NA NR [~ 2400000] (imputed) 0 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST006900 Genome-wide genotyping array 681275 2019-01-14 30124842 Yengo L 2018-08-16 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30124842 Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry. Height 456,426 European ancestry individuals, 237,103 individuals NA NR [~ 2400000] (imputed) 0 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST006901 Genome-wide genotyping array 693529 2019-02-27 30527956 Rhodes CJ 2018-12-05 Lancet Respir Med www.ncbi.nlm.nih.gov/pubmed/30527956 Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis. Pulmonary arterial hypertension 2,085 European ancestry cases, 9,659 European ancestry controls NA Illumina [~ 7727590] (imputed) 3 pulmonary arterial hypertension http://www.ebi.ac.uk/efo/EFO_0001361 GCST007228 Genome-wide genotyping array, Genome-wide sequencing 11744 2019-09-24 31455332 Zhang Y 2019-08-28 BMC Med www.ncbi.nlm.nih.gov/pubmed/31455332 Dissecting genetic factors affecting phenylephrine infusion rates during anesthesia: a genome-wide association study employing EHR data. Phenylephrine infusion rate during anesthesia 1,534 European ancestry individuals NA Illumina [up to 4929806] (imputed) 11 response to phenylephrine http://www.ebi.ac.uk/efo/EFO_0010152 GCST008755 Genome-wide genotyping array 1534 2020-01-20 31887566 Carrion-Castillo A 2019-11-29 Cortex www.ncbi.nlm.nih.gov/pubmed/31887566 Genetic effects on planum temporale asymmetry and their limited relevance to neurodevelopmental disorders, intelligence or educational attainment. Left planum temporale grey matter volume 18,037 British ancestry individuals NA Affymetrix [15120452] (imputed) 1 superior temporal gyrus volume measurement http://www.ebi.ac.uk/efo/EFO_0010331 GCST009460 Genome-wide genotyping array 18037 2020-01-20 31887566 Carrion-Castillo A 2019-11-29 Cortex www.ncbi.nlm.nih.gov/pubmed/31887566 Genetic effects on planum temporale asymmetry and their limited relevance to neurodevelopmental disorders, intelligence or educational attainment. Right planum temporale grey matter volume 18,039 British ancestry individuals NA Affymetrix [15120452] (imputed) 1 superior temporal gyrus volume measurement http://www.ebi.ac.uk/efo/EFO_0010331 GCST009458 Genome-wide genotyping array 18039 2020-01-20 31887566 Carrion-Castillo A 2019-11-29 Cortex www.ncbi.nlm.nih.gov/pubmed/31887566 Genetic effects on planum temporale asymmetry and their limited relevance to neurodevelopmental disorders, intelligence or educational attainment. Planum temporale asymmetry index 18,049 British ancestry individuals NA Affymetrix [15120452] (imputed) 2 superior temporal gyrus volume measurement http://www.ebi.ac.uk/efo/EFO_0010331 GCST009459 Genome-wide genotyping array 18049 2019-06-28 30591961 Huang L 2018-12-24 Sci China Life Sci www.ncbi.nlm.nih.gov/pubmed/30591961 Genome-wide analysis identified 17 new loci influencing intraocular pressure in Chinese population. Intraocular pressure 5,571 Chinese ancestry individuals 2,981 Chinese ancestry individuals Illumina [at least 900015] (imputed) 28 intraocular pressure measurement http://www.ebi.ac.uk/efo/EFO_0004695 GCST007998 Genome-wide genotyping array 5571 2019-05-07 30586722 Aragam KG 2018-11-11 Circulation www.ncbi.nlm.nih.gov/pubmed/30586722 Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery. Heart failure 6,504 European ancestry cases, 387,652 European ancestry controls 4,042 European ancestry cases, 8,777 European ancestry controls NR [NR] 0 heart failure http://www.ebi.ac.uk/efo/EFO_0003144 GCST007715 Genome-wide genotyping array 394156 2019-05-07 30586722 Aragam KG 2018-11-11 Circulation www.ncbi.nlm.nih.gov/pubmed/30586722 Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery. Nonischemic cardiomyopathy 1,816 European ancestry cases, 388,326 European ancestry controls 3,282 European ancestry cases, 13,913 European ancestry controls NR [NR] 0 nonischemic cardiomyopathy http://www.ebi.ac.uk/efo/EFO_0009881 GCST007714 Genome-wide genotyping array 390142 2019-01-21 30582445 Mola-Caminal M 2019-01-01 Circ Res www.ncbi.nlm.nih.gov/pubmed/30582445 PATJ Low Frequency Variants Are Associated With Worse Ischemic Stroke Functional Outcome. 3-month functional outcome in ischaemic stroke (modified Rankin score) 1,225 European ancestry individuals 1,791 European ancestry individuals Illumina [4480015] (imputed) 1 stroke outcome severity measurement http://www.ebi.ac.uk/efo/EFO_0009603 GCST006935 Genome-wide genotyping array 1225 2019-03-25 30589442 Whitfield JB 2018-12-27 Alcohol Clin Exp Res www.ncbi.nlm.nih.gov/pubmed/30589442 Biomarker and genomic risk factors for liver function test abnormality in hazardous drinkers. Gamma glutamyl transferase levels in excessive alcohol consumption 951 individuals NA Illumina [~ 7800000] (imputed) 16 serum gamma-glutamyl transferase measurement http://www.ebi.ac.uk/efo/EFO_0004532 GCST007376 Genome-wide genotyping array 951 2019-03-25 30589442 Whitfield JB 2018-12-27 Alcohol Clin Exp Res www.ncbi.nlm.nih.gov/pubmed/30589442 Biomarker and genomic risk factors for liver function test abnormality in hazardous drinkers. Alanine aminotransferase levels in excessive alcohol consumption 951 individuals NA Illumina [~ 7800000] (imputed) 28 serum alanine aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004735 GCST007381 Genome-wide genotyping array 951 2019-03-25 30589442 Whitfield JB 2018-12-27 Alcohol Clin Exp Res www.ncbi.nlm.nih.gov/pubmed/30589442 Biomarker and genomic risk factors for liver function test abnormality in hazardous drinkers. Aspartate aminotransferase levels in excessive alcohol consumption 951 individuals NA Illumina [~ 7800000] (imputed) 19 aspartate aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004736 GCST007377 Genome-wide genotyping array 951 2019-03-25 30589442 Whitfield JB 2018-12-27 Alcohol Clin Exp Res www.ncbi.nlm.nih.gov/pubmed/30589442 Biomarker and genomic risk factors for liver function test abnormality in hazardous drinkers. Gamma glutamyl transferase levels in low alcohol consumption 8,716 individuals NA Illumina [~ 7800000] (imputed) 25 serum gamma-glutamyl transferase measurement http://www.ebi.ac.uk/efo/EFO_0004532 GCST007380 Genome-wide genotyping array 8716 2019-03-25 30589442 Whitfield JB 2018-12-27 Alcohol Clin Exp Res www.ncbi.nlm.nih.gov/pubmed/30589442 Biomarker and genomic risk factors for liver function test abnormality in hazardous drinkers. Alanine aminotransferase levels in low alcohol consumption 8,716 individuals NA Illumina [~ 7800000] (imputed) 16 serum alanine aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004735 GCST007379 Genome-wide genotyping array 8716 2019-03-25 30589442 Whitfield JB 2018-12-27 Alcohol Clin Exp Res www.ncbi.nlm.nih.gov/pubmed/30589442 Biomarker and genomic risk factors for liver function test abnormality in hazardous drinkers. Aspartate aminotransferase levels in low alcohol consumption 8,716 individuals NA Illumina [~ 7800000] (imputed) 39 aspartate aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004736 GCST007378 Genome-wide genotyping array 8716 2019-07-01 31005965 Coltell O 2019-04-21 Am J Clin Nutr www.ncbi.nlm.nih.gov/pubmed/31005965 Association between taste perception and adiposity in overweight or obese older subjects with metabolic syndrome and identification of novel taste-related genes. Sweet taste perception in obesity with metabolic syndrome 378 individuals NA Illumina [622468] 6 sensory perception of taste http://purl.obolibrary.org/obo/GO_0050909 GCST008018 Genome-wide genotyping array 378 2019-07-01 31005965 Coltell O 2019-04-21 Am J Clin Nutr www.ncbi.nlm.nih.gov/pubmed/31005965 Association between taste perception and adiposity in overweight or obese older subjects with metabolic syndrome and identification of novel taste-related genes. Salty taste perception in obesity with metabolic syndrome 378 individuals NA Illumina [622468] 3 sensory perception of taste http://purl.obolibrary.org/obo/GO_0050909 GCST008024 Genome-wide genotyping array 378 2019-07-01 31005965 Coltell O 2019-04-21 Am J Clin Nutr www.ncbi.nlm.nih.gov/pubmed/31005965 Association between taste perception and adiposity in overweight or obese older subjects with metabolic syndrome and identification of novel taste-related genes. Sour taste perception in obesity with metabolic syndrome 378 individuals NA Illumina [622468] 2 sensory perception of taste http://purl.obolibrary.org/obo/GO_0050909 GCST008023 Genome-wide genotyping array 378 2019-07-01 31005965 Coltell O 2019-04-21 Am J Clin Nutr www.ncbi.nlm.nih.gov/pubmed/31005965 Association between taste perception and adiposity in overweight or obese older subjects with metabolic syndrome and identification of novel taste-related genes. Umami taste perception in obesity with metabolic syndrome 378 individuals NA Illumina [622468] 4 sensory perception of taste http://purl.obolibrary.org/obo/GO_0050909 GCST008022 Genome-wide genotyping array 378 2019-07-01 31005965 Coltell O 2019-04-21 Am J Clin Nutr www.ncbi.nlm.nih.gov/pubmed/31005965 Association between taste perception and adiposity in overweight or obese older subjects with metabolic syndrome and identification of novel taste-related genes. Taste perception (total score including phenylthiocarbamide) in obesity with metabolic syndrome 369 individuals NA Illumina [622468] 5 sensory perception of taste http://purl.obolibrary.org/obo/GO_0050909 GCST008020 Genome-wide genotyping array 369 2019-07-01 31005965 Coltell O 2019-04-21 Am J Clin Nutr www.ncbi.nlm.nih.gov/pubmed/31005965 Association between taste perception and adiposity in overweight or obese older subjects with metabolic syndrome and identification of novel taste-related genes. Taste perception (total score including 6-n-propylthiouracil) in obesity with metabolic syndrome up to 372 individuals NA Illumina [622468] 2 sensory perception of taste http://purl.obolibrary.org/obo/GO_0050909 GCST008021 Genome-wide genotyping array 372 2019-07-01 31005965 Coltell O 2019-04-21 Am J Clin Nutr www.ncbi.nlm.nih.gov/pubmed/31005965 Association between taste perception and adiposity in overweight or obese older subjects with metabolic syndrome and identification of novel taste-related genes. Bitter taste perception (6-n-propylthiouracil) in obesity with metabolic syndrome 368 individuals NA Illumina [622468] 8 sensory perception of bitter taste http://purl.obolibrary.org/obo/GO_0050913 GCST008017 Genome-wide genotyping array 368 2019-07-01 31005965 Coltell O 2019-04-21 Am J Clin Nutr www.ncbi.nlm.nih.gov/pubmed/31005965 Association between taste perception and adiposity in overweight or obese older subjects with metabolic syndrome and identification of novel taste-related genes. Bitter taste perception (phenylthiocarbamide) in obesity with metabolic syndrome 372 individuals NA Illumina [622468] 10 sensory perception of bitter taste http://purl.obolibrary.org/obo/GO_0050913 GCST008019 Genome-wide genotyping array 372 2019-10-09 31498392 Kusic DM 2019-09-09 Mil Med www.ncbi.nlm.nih.gov/pubmed/31498392 rs11670527 Upstream of ZNF264 Associated with Body Mass Index in the Coriell Personalized Medicine Collaborative. Body mass index 4,822 European ancestry individuals, 429 African American, Asian, Native Hawaiian/other Pacific Islander, Native American/Alaska native or unknown ancestry individuals NA Affymetrix [232536] 1 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST008823 Genome-wide genotyping array 5251 2019-11-04 30239722 Pulit SL 2018-09-14 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30239722 Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry. Waist-to-hip ratio adjusted for BMI 379,501 European ancestry female individuals NA NR [~ 27400000] (imputed) 258 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST008994 Genome-wide genotyping array 379501 2019-11-04 30239722 Pulit SL 2018-09-14 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30239722 Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry. Waist-to-hip ratio adjusted for BMI 315,284 European ancestry male individuals NA NR [~ 27400000] (imputed) 84 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST008995 Genome-wide genotyping array 315284 2019-11-04 30239722 Pulit SL 2018-09-14 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30239722 Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry. Waist-hip ratio 697,734 European ancestry individuals NA NR [~ 27400000] (imputed) 316 waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0004343 GCST008996 Genome-wide genotyping array 697734 2019-11-04 30239722 Pulit SL 2018-09-14 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30239722 Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry. Waist-hip ratio 381,152 European female individuals NA NR [~ 27400000] (imputed) 195 waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0004343 GCST008997 Genome-wide genotyping array 381152 2019-11-04 30239722 Pulit SL 2018-09-14 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30239722 Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry. Waist-hip ratio 316,772 European ancestry male individuals NA NR [~ 27400000] (imputed) 74 waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0004343 GCST008998 Genome-wide genotyping array 316772 2019-11-05 30239722 Pulit SL 2018-09-14 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30239722 Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry. Body mass index 806,834 European ancestry individuals NA NR [~ 27400000] (imputed) 670 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST009004 Genome-wide genotyping array 806834 2019-11-05 30239722 Pulit SL 2018-09-14 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30239722 Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry. Body mass index 434,794 European ancestry female individuals NA NR [~ 27400000] (imputed) 281 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST009003 Genome-wide genotyping array 434794 2019-11-04 30239722 Pulit SL 2018-09-14 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30239722 Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry. Body mass index 374,756 European ancestry male individuals NA NR [~ 27400000] (imputed) 221 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST009001 Genome-wide genotyping array 374756 2019-11-04 30239722 Pulit SL 2018-09-14 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30239722 Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry. Waist-to-hip ratio adjusted for BMI 694,649 European ancestry individuals 7,721 European ancestry individuals NR [~ 27400000] (imputed) 0 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST008999 Genome-wide genotyping array 694649 2020-01-09 31490055 Sun J 2019-09-06 Can J Surg www.ncbi.nlm.nih.gov/pubmed/31490055 A genome-wide association study of cocaine use disorder accounting for phenotypic heterogeneity and gene–environment interaction Cocaine use disorder 2,070 African American individuals, 1,570 European ancestry individuals 918 African American individuals, 1,382 European ancestry individuals Illumina [up to 47104916] (imputed) 4 cocaine use disorder http://www.ebi.ac.uk/efo/EFO_0010445 GCST009385 Genome-wide genotyping array 3640 2020-01-09 31490055 Sun J 2019-09-06 Can J Surg www.ncbi.nlm.nih.gov/pubmed/31490055 A genome-wide association study of cocaine use disorder accounting for phenotypic heterogeneity and gene–environment interaction Cocaine use disorder x non-traditional parental care interaction 2,070 African American individuals, 1,570 European ancestry individuals 918 African American individuals, 1,382 European ancestry individuals Illumina [up to 47104916] (imputed) 1 cocaine use disorder, social environment measurement http://www.ebi.ac.uk/efo/EFO_0010445, http://www.ebi.ac.uk/efo/EFO_0010552 GCST009386 Genome-wide genotyping array 3640 2020-01-09 31490055 Sun J 2019-09-06 Can J Surg www.ncbi.nlm.nih.gov/pubmed/31490055 A genome-wide association study of cocaine use disorder accounting for phenotypic heterogeneity and gene–environment interaction Cocaine use disorder x change in residence interaction 2,070 African American individuals, 1,570 European ancestry individuals 918 African American individuals, 1,382 European ancestry individuals Illumina [up to 47104916] (imputed) 3 cocaine use disorder, social environment measurement http://www.ebi.ac.uk/efo/EFO_0010445, http://www.ebi.ac.uk/efo/EFO_0010552 GCST009387 Genome-wide genotyping array 3640 2020-01-09 31490055 Sun J 2019-09-06 Can J Surg www.ncbi.nlm.nih.gov/pubmed/31490055 A genome-wide association study of cocaine use disorder accounting for phenotypic heterogeneity and gene–environment interaction Cocaine use disorder x traumatic experience interaction 2,070 African American individuals, 1,570 European ancestry individuals 918 African American individuals, 1,382 European ancestry individuals Illumina [up to 47104916] (imputed) 0 cocaine use disorder, childhood trauma measurement http://www.ebi.ac.uk/efo/EFO_0010445, http://www.ebi.ac.uk/efo/EFO_0007979 GCST009388 Genome-wide genotyping array 3640 2020-01-09 31490055 Sun J 2019-09-06 Can J Surg www.ncbi.nlm.nih.gov/pubmed/31490055 A genome-wide association study of cocaine use disorder accounting for phenotypic heterogeneity and gene–environment interaction Cocaine use disorder x household drinking and illicit drug use interaction 2,070 African American individuals, 1,570 European ancestry individuals 918 African American individuals, 1,382 European ancestry individuals Illumina [up to 47104916] (imputed) 0 cocaine use disorder, social environment measurement http://www.ebi.ac.uk/efo/EFO_0010445, http://www.ebi.ac.uk/efo/EFO_0010552 GCST009389 Genome-wide genotyping array 3640 2020-01-09 31490055 Sun J 2019-09-06 Can J Surg www.ncbi.nlm.nih.gov/pubmed/31490055 A genome-wide association study of cocaine use disorder accounting for phenotypic heterogeneity and gene–environment interaction Cocaine use disorder x household tobacco use interaction 2,070 African American individuals, 1,570 European ancestry individuals 918 African American individuals, 1,382 European ancestry individuals Illumina [up to 47104916] (imputed) 2 cocaine use disorder, social environment measurement http://www.ebi.ac.uk/efo/EFO_0010445, http://www.ebi.ac.uk/efo/EFO_0010552 GCST009390 Genome-wide genotyping array 3640 2021-06-01 31596850 Turchin MC 2019-10-09 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31596850 Bayesian multivariate reanalysis of large genetic studies identifies many new associations. Blood lipid levels (multivariate analysis) up to 188,577 individuals NA NR [up to 2004701] 0 total cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0004611, http://www.ebi.ac.uk/efo/EFO_0004612 GCST011765 Genome-wide genotyping array 188577 2021-06-01 31596850 Turchin MC 2019-10-09 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31596850 Bayesian multivariate reanalysis of large genetic studies identifies many new associations. Body morphological traits (multivariate analysis) up to 224,459 individuals NA NR [up to 2363881] 0 BMI-adjusted waist-hip ratio, body mass index, body height http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004339 GCST011764 Genome-wide genotyping array 224459 2021-06-01 31596850 Turchin MC 2019-10-09 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31596850 Bayesian multivariate reanalysis of large genetic studies identifies many new associations. Red blood cell traits (multivariate analysis) up to 173,480 individuals NA NR [up to 8649095] 0 hemoglobin measurement, erythrocyte count, mean corpuscular hemoglobin concentration, mean corpuscular volume, hematocrit, mean corpuscular hemoglobin http://www.ebi.ac.uk/efo/EFO_0004509, http://www.ebi.ac.uk/efo/EFO_0004305, http://www.ebi.ac.uk/efo/EFO_0004528, http://www.ebi.ac.uk/efo/EFO_0004526, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0004527 GCST011763 Genome-wide genotyping array 173480 2021-06-01 31596850 Turchin MC 2019-10-09 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31596850 Bayesian multivariate reanalysis of large genetic studies identifies many new associations. Blood pressure traits (multi-trait analysis) up to 69,395 individuals NA NR [2387851] 0 pulse pressure measurement, mean arterial pressure, diastolic blood pressure, systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0005763, http://www.ebi.ac.uk/efo/EFO_0006340, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0006335 GCST011762 Genome-wide genotyping array 69395 2021-06-01 31596850 Turchin MC 2019-10-09 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31596850 Bayesian multivariate reanalysis of large genetic studies identifies many new associations. Bone density traits (multivariate analysis) up to 32,965 individuals NA NR [8938035] 0 volumetric bone mineral density http://www.ebi.ac.uk/efo/EFO_0007620 GCST011761 Genome-wide genotyping array 32965 2021-06-01 31596850 Turchin MC 2019-10-09 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31596850 Bayesian multivariate reanalysis of large genetic studies identifies many new associations. Kidney function traits (multivariate analysis) up to 67,093 individuals NA NR [2333498] 0 creatinine measurement, cystatin C measurement, chronic kidney disease, urinary albumin to creatinine ratio, Moderate albuminuria http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0004617, http://www.ebi.ac.uk/efo/EFO_0003884, http://www.ebi.ac.uk/efo/EFO_0007778, http://purl.obolibrary.org/obo/HP_0012594 GCST011760 Genome-wide genotyping array 67093 2021-06-01 31596850 Turchin MC 2019-10-09 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31596850 Bayesian multivariate reanalysis of large genetic studies identifies many new associations. Fasting insulin, fasting glucose, HOMA-B, HOMA-IR (multivariate analysis) up to 46,186 individuals NA NR [2333328] 0 fasting blood glucose measurement, HOMA-B, HOMA-IR, fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004465, http://www.ebi.ac.uk/efo/EFO_0004469, http://www.ebi.ac.uk/efo/EFO_0004501, http://www.ebi.ac.uk/efo/EFO_0004466 GCST011759 Genome-wide genotyping array 46186 2021-06-01 31596850 Turchin MC 2019-10-09 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31596850 Bayesian multivariate reanalysis of large genetic studies identifies many new associations. Iron level traits (multivariate analysis) up to 48,972 individuals NA NR [1985313] 0 transferrin saturation measurement, ferritin measurement, transferrin measurement, serum iron measurement http://www.ebi.ac.uk/efo/EFO_0006333, http://www.ebi.ac.uk/efo/EFO_0004459, http://www.ebi.ac.uk/efo/EFO_0006341, http://www.ebi.ac.uk/efo/EFO_0006332 GCST011758 Genome-wide genotyping array 48972 2021-06-01 31596850 Turchin MC 2019-10-09 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31596850 Bayesian multivariate reanalysis of large genetic studies identifies many new associations. Number of children ever born and age at first birth (multivariate analysis) up to 343,072 individuals NA NR [2395561] 0 age at first birth measurement, number of children ever born measurement http://www.ebi.ac.uk/efo/EFO_0009101, http://www.ebi.ac.uk/efo/EFO_0009102 GCST011757 Genome-wide genotyping array 343072 2021-06-01 31596850 Turchin MC 2019-10-09 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31596850 Bayesian multivariate reanalysis of large genetic studies identifies many new associations. Brain structure volumes (multivariate analysis) up to 30,717 individuals NA NR [6271117] 0 pallidum volume, nucleus accumbens volume, hippocampal volume, intracranial volume measurement, putamen volume, amygdala volume, thalamus volume, caudate nucleus volume http://www.ebi.ac.uk/efo/EFO_0006933, http://www.ebi.ac.uk/efo/EFO_0006931, http://www.ebi.ac.uk/efo/EFO_0005035, http://www.ebi.ac.uk/efo/EFO_0004886, http://www.ebi.ac.uk/efo/EFO_0006932, http://www.ebi.ac.uk/efo/EFO_0006934, http://www.ebi.ac.uk/efo/EFO_0006935, http://www.ebi.ac.uk/efo/EFO_0004830 GCST011756 Genome-wide genotyping array 30717 2019-12-10 31679650 Nath AP 2019-10-30 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31679650 Multivariate Genome-Wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy. Cytokine levels 9,263 Finnish ancestry individuals NA Illumina [6022229] (imputed) 10 interferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement http://www.ebi.ac.uk/efo/EFO_0008165, http://www.ebi.ac.uk/efo/EFO_0008264, http://www.ebi.ac.uk/efo/EFO_0008184, http://www.ebi.ac.uk/efo/EFO_0004750, http://www.ebi.ac.uk/efo/EFO_0008293, http://www.ebi.ac.uk/efo/EFO_0004810, http://www.ebi.ac.uk/efo/EFO_0004753, http://www.ebi.ac.uk/efo/EFO_0008174, http://www.ebi.ac.uk/efo/EFO_0004762, http://www.ebi.ac.uk/efo/EFO_0008130, http://www.ebi.ac.uk/efo/EFO_0008142 GCST009243 Genome-wide genotyping array 9263 2019-12-10 31679650 Nath AP 2019-10-30 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31679650 Multivariate Genome-Wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy. Cytokine network levels (multivariate analysis) 9,263 Finnish ancestry individuals NA Illumina [6022229] (imputed) 13 interferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement http://www.ebi.ac.uk/efo/EFO_0008165, http://www.ebi.ac.uk/efo/EFO_0008264, http://www.ebi.ac.uk/efo/EFO_0008184, http://www.ebi.ac.uk/efo/EFO_0004750, http://www.ebi.ac.uk/efo/EFO_0008293, http://www.ebi.ac.uk/efo/EFO_0004810, http://www.ebi.ac.uk/efo/EFO_0004753, http://www.ebi.ac.uk/efo/EFO_0008174, http://www.ebi.ac.uk/efo/EFO_0004762, http://www.ebi.ac.uk/efo/EFO_0008130, http://www.ebi.ac.uk/efo/EFO_0008142 GCST009244 Genome-wide genotyping array 9263 2019-09-23 31477735 Liu X 2019-09-02 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31477735 Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration. Spontaneous preterm birth (preterm birth) 4,775 European ancestry cases, 60,148 European ancestry controls NA Illumina [7545601] (imputed) 0 spontaneous preterm birth http://www.ebi.ac.uk/efo/EFO_0006917 GCST008754 Genome-wide genotyping array 64923 2019-09-23 31477735 Liu X 2019-09-02 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31477735 Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration. Early spontaneous preterm birth 1,139 European ancestry cases, 60,148 European ancestry controls 107 Finnish ancestry infant cases, 865 Finnish ancestry infant controls Illumina [7588467] (imputed) 2 spontaneous preterm birth http://www.ebi.ac.uk/efo/EFO_0006917 GCST008753 Genome-wide genotyping array 61287 2019-09-23 31477735 Liu X 2019-09-02 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31477735 Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration. Post-term birth 7,888 European ancestry cases, 60,148 European ancestry controls 670 European ancestry infant cases, 5,626 European ancestry infant controls Illumina [7583965] (imputed) 1 birth measurement http://www.ebi.ac.uk/efo/EFO_0006921 GCST008752 Genome-wide genotyping array 68036 2019-09-23 31477735 Liu X 2019-09-02 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31477735 Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration. Gestational age at birth (child effect) 84,689 European ancestry infants 9,291 European ancestry infants Illumina [7646297] (imputed) 1 gestational age http://www.ebi.ac.uk/efo/EFO_0005112 GCST008751 Genome-wide genotyping array 84689 2019-10-30 30976013 Dekker AM 2019-04-11 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30976013 Exome array analysis of rare and low frequency variants in amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis 4,244 European ancestry cases, 3,106 European ancestry controls NA Illumina [233331] 1 amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0000253 GCST008978 Exome genotyping array [Exome array] 7350 2019-11-22 31659325 Malhotra R 2019-10-28 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31659325 HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype. Thoracic aortic calcification levels 8,422 European ancestry individuals NA Affymetrix, Illumina [9000000] (imputed) 8 thoracic aortic calcification measurement http://www.ebi.ac.uk/efo/EFO_0010273 GCST009090 Genome-wide genotyping array 8422 2019-11-22 31659325 Malhotra R 2019-10-28 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31659325 HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype. Abdominal aortic calcification levels 9,417 European ancestry individuals 1,595 African American individuals, 496 Hispanic or Latin American individuals Affymetrix, Illumina [9000000] (imputed) 8 abdominal aortic calcification measurement http://www.ebi.ac.uk/efo/EFO_0010272 GCST009091 Genome-wide genotyping array 9417 2020-01-07 28346444 Wright DJ 2017-03-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28346444 Genetic variants associated with mosaic Y chromosome loss highlight cell cycle genes and overlap with cancer susceptibility. Mosaic loss of chromosome Y (Y chromosome dosage) 67,034 European ancestry men 8,715 European ancestry men, 9,793 men Affymetrix [at least 641018] (imputed) 19 mosaic loss of chromosome Y measurement http://www.ebi.ac.uk/efo/EFO_0007783 GCST009375 Genome-wide genotyping array 67034 2020-01-27 28346444 Wright DJ 2017-03-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28346444 Genetic variants associated with mosaic Y chromosome loss highlight cell cycle genes and overlap with cancer susceptibility. Cancer 7,745 European ancestry male cases, 58,562 European ancestry male controls NA Affymetrix [at least 641018] (imputed) 1 cancer http://www.ebi.ac.uk/efo/EFO_0000311 GCST009503 Genome-wide genotyping array 66307 2020-07-03 31801373 Choi Y 2019-12-05 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/31801373 Causal Associations Between Serum Bilirubin Levels and Decreased Stroke Risk: A Two-Sample Mendelian Randomization Study. Bilirubin levels 25,406 Korean ancestry individuals NA NR [NR] (imputed) 7 bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004570 GCST010117 Genome-wide genotyping array 25406 2019-08-19 31289104 Kawamura Y 2019-07-08 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/31289104 Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout. Gout vs. Hyperuricemia 945 Japanese ancestry cases, 1,003 Japanese ancestry controls 1,915 Japanese ancestry cases, 2,146 Japanese ancestry controls Illumina [569200] 11 gout, hyperuricemia http://www.ebi.ac.uk/efo/EFO_0004274, http://www.ebi.ac.uk/efo/EFO_0009104 GCST008460 Genome-wide genotyping array 1948 2019-09-02 31294817 Chen J 2019-07-11 Nicotine Tob Res www.ncbi.nlm.nih.gov/pubmed/31294817 Genome-Wide Meta-Analyses of FTND and TTFC Phenotypes. Fagerstrӧm test for nicotine dependence 19,431 European ancestry individuals 7,010 European ancestry individuals Affymetrix, Illumina [NR] (imputed) 2 nicotine dependence symptom count http://www.ebi.ac.uk/efo/EFO_0009262 GCST008548 Genome-wide genotyping array 19431 2019-09-02 31294817 Chen J 2019-07-11 Nicotine Tob Res www.ncbi.nlm.nih.gov/pubmed/31294817 Genome-Wide Meta-Analyses of FTND and TTFC Phenotypes. Time to smoke first cigarette in the morning 18,567 European ancestry individuals 10,061 European ancestry individuals Affymetrix, Illumina [NR] (imputed) 4 time to first cigarette measurement http://www.ebi.ac.uk/efo/EFO_0010126 GCST008547 Genome-wide genotyping array 18567 2019-08-01 30092369 Mainali B 2018-08-06 Papillomavirus Res www.ncbi.nlm.nih.gov/pubmed/30092369 Variants in Immune-related Genes and Genital HPV 16 Persistence in Men. Infection persistence (>18 months) in genital human papillomavirus 16 infection 21 European ancestry male cases, 15 Brazilian ancestry male cases, 4 African-American male cases, 62 European ancestry male controls, 69 Brazilian ancestry male controls, 20 African-American male controls NA Affymetrix [605885] 2 chronic human papillomavirus infection http://www.ebi.ac.uk/efo/EFO_0010060 GCST008308 Genome-wide genotyping array 191 2019-12-05 31649266 Gallagher CS 2019-10-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31649266 Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis. Uterine fibroids and heavy menstrual bleeding 3,409 European ancestry cases, 199,171 European ancestry controls NA Affymetrix [10308721] (imputed) 7 uterine fibroid, Menorrhagia http://www.ebi.ac.uk/efo/EFO_0000731, http://purl.obolibrary.org/obo/HP_0000132 GCST009156 Genome-wide genotyping array 202580 2019-12-05 31649266 Gallagher CS 2019-10-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31649266 Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis. Heavy menstrual bleeding 9,813 European ancestry cases, 210,946 European ancestry controls NA Affymetrix [10308721] (imputed) 3 Menorrhagia http://purl.obolibrary.org/obo/HP_0000132 GCST009157 Genome-wide genotyping array 220759 2019-12-05 31649266 Gallagher CS 2019-10-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31649266 Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis. Uterine fibroids 20,406 European ancestry cases, 223,918 European ancestry controls 15,068 European ancestry cases, 43,587 European ancestry controls Affymetrix, Illumina [8662096] (imputed) 55 uterine fibroid http://www.ebi.ac.uk/efo/EFO_0000731 GCST009158 Genome-wide genotyping array 244324 2019-02-27 30542056 Petridis C 2018-12-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30542056 Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne. Acne (severe) 5,602 European ancestry cases, 21,120 European ancestry controls NA Illumina [up to 7441713] (imputed) 20 acne http://www.ebi.ac.uk/efo/EFO_0003894 GCST007234 Genome-wide genotyping array 26722 2020-02-06 31711042 Li X 2019-11-11 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/31711042 Genome-wide association study identifies SIAH3 locus influencing the rate of ventricular enlargement in non-demented elders. Rate of ventricular enlargement 507 European ancestry individuals NA Illumina [1231747] 13 ventricular enlargement measurement http://www.ebi.ac.uk/efo/EFO_0010570 GCST009557 Genome-wide genotyping array 507 2019-03-11 30573655 Acosta-Herrera M 2018-12-20 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/30573655 Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases. Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) up to 4,595 European ancestry rheumatoid arthritis cases, up to 3,154 European ancestry systemic lupus erythematosus cases, up to 2,281 European ancestry systemic sclerosis cases, up to 1,674 European ancestry idiopathic inflammatory myopathy cases, 19,704 European ancestry controls NA Illumina [6450125] (imputed) 26 systemic scleroderma, rheumatoid arthritis, myositis, systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0000717, http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0000783, http://www.ebi.ac.uk/efo/EFO_0002690 GCST007278 Genome-wide genotyping array 31408 2019-04-17 30578877 Dahlin A 2018-12-19 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/30578877 Large-scale, multi-ethnic genome-wide association study identifies novel loci contributing to asthma susceptibility in adults. Adult asthma 16,274 European ancestry cases, 38,269 European ancestry controls 10,365 European ancestry cases, 16,110 European ancestry controls, cases and controls (see Moffatt et al 2010) Affymetrix [7230512] (imputed) 3 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST007596 Genome-wide genotyping array 54543 2019-04-17 30578877 Dahlin A 2018-12-19 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/30578877 Large-scale, multi-ethnic genome-wide association study identifies novel loci contributing to asthma susceptibility in adults. Adult asthma 611 African American cases, 1,915 African American controls 10,365 European ancestry cases, 16,110 European ancestry controls, cases and controls (see Moffatt et al 2010) Affymetrix [12660172] (imputed) 0 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST007599 Genome-wide genotyping array 2526 2019-04-17 30578877 Dahlin A 2018-12-19 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/30578877 Large-scale, multi-ethnic genome-wide association study identifies novel loci contributing to asthma susceptibility in adults. Adult asthma 1,300 Asian ancestry cases, 4,927 Asian ancestry controls 10,365 European ancestry cases, 16,110 European ancestry controls, cases and controls (see Moffatt et al 2010) Affymetrix [6389101] (imputed) 0 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST007598 Genome-wide genotyping array 6227 2019-04-17 30578877 Dahlin A 2018-12-19 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/30578877 Large-scale, multi-ethnic genome-wide association study identifies novel loci contributing to asthma susceptibility in adults. Adult asthma 1,320 Hispanic ancestry cases, 4,007 Hispanic ancestry controls 10,365 European ancestry cases, 16,110 European ancestry controls, cases and controls (see Moffatt et al 2010) Affymetrix [7735858] (imputed) 0 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST007597 Genome-wide genotyping array 5327 2019-01-25 30583798 Bovijn J 2018-12-21 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30583798 GWAS Identifies Risk Locus for Erectile Dysfunction and Implicates Hypothalamic Neurobiology and Diabetes in Etiology. Erectile dysfunction 6,175 European ancestry male cases, 217,630 European ancestry male controls NA Affymetrix, Illumina [at least 807411] (imputed) 23 erectile dysfunction http://www.ebi.ac.uk/efo/EFO_0004234 GCST006956 Genome-wide genotyping array 223805 2019-03-28 30586737 Sabater-Lleal M 2018-11-20 Circulation www.ncbi.nlm.nih.gov/pubmed/30586737 Genome-Wide Association Trans-Ethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels. Factor VIII levels 25,897 European ancestry individuals, 4,500 African American individuals, 773 Asian ancestry individuals, 1,440 Hispanic individuals NA Affymetrix, Illumina [13887196] (imputed) 66 factor VIII measurement http://www.ebi.ac.uk/efo/EFO_0004630 GCST007445 Genome-wide genotyping array 32610 2019-03-28 30586737 Sabater-Lleal M 2018-11-20 Circulation www.ncbi.nlm.nih.gov/pubmed/30586737 Genome-Wide Association Trans-Ethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels. vWF levels 42,379 European ancestry individuals, 3,700 African American individuals, 275 Hispanic individuals NA Affymetrix, Illumina [10537485] (imputed) 87 von Willebrand factor measurement http://www.ebi.ac.uk/efo/EFO_0004629 GCST007446 Genome-wide genotyping array 46354 2019-03-28 30586737 Sabater-Lleal M 2018-11-20 Circulation www.ncbi.nlm.nih.gov/pubmed/30586737 Genome-Wide Association Trans-Ethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels. vWF and FVIII levels Up to 42,379 European ancestry individuals, up to 4,500 African American individuals, up to 773 Asian ancestry individuals, up to 1,440 Hispanic individuals NA Affymetrix, Illumina [up to 13887196] (imputed) 2 factor VIII measurement, von Willebrand factor measurement http://www.ebi.ac.uk/efo/EFO_0004630, http://www.ebi.ac.uk/efo/EFO_0004629 GCST007447 Genome-wide genotyping array 49092 2020-01-21 31518406 Abdellaoui A 2019-09-13 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31518406 Phenome-wide investigation of health outcomes associated with genetic predisposition to loneliness. Loneliness 511,280 European ancestry individuals NA Affymetrix, Illumina [up to 14113458] (imputed) 19 loneliness measurement http://www.ebi.ac.uk/efo/EFO_0007865 GCST009463 Genome-wide genotyping array 511280 2019-09-16 31482010 Liu C 2019-08-29 NPJ Genom Med www.ncbi.nlm.nih.gov/pubmed/31482010 Genome-wide association study for proliferative diabetic retinopathy in Africans. Proliferative diabetic retinopathy 64 African ancestry cases, 227 African ancestry controls 19 African American cases, 50 African American controls Affymetrix, Illumina [18433741] (imputed) 4 proliferative diabetic retinopathy http://www.ebi.ac.uk/efo/EFO_0009322 GCST008668 Genome-wide genotyping array 291 2019-07-12 31043756 Stahl EA 2019-05-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31043756 Genome-wide association study identifies 30 loci associated with bipolar disorder. Bipolar I disorder 14,879 European ancestry cases, 31,358 European ancestry controls NA NR [9372253] (imputed) 61 bipolar I disorder http://www.ebi.ac.uk/efo/EFO_0009963 GCST008115 Genome-wide genotyping array 46237 2019-07-12 31043756 Stahl EA 2019-05-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31043756 Genome-wide association study identifies 30 loci associated with bipolar disorder. Bipolar II disorder 3,421 European ancestry cases, 31,358 European ancestry controls NA NR [9372253] (imputed) 5 bipolar II disorder http://www.ebi.ac.uk/efo/EFO_0009964 GCST008116 Genome-wide genotyping array 34779 2019-07-12 31043756 Stahl EA 2019-05-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31043756 Genome-wide association study identifies 30 loci associated with bipolar disorder. Schizoaffective disorder-bipolar type 977 European ancestry cases, 31,358 European ancestry controls NA NR [9372253] (imputed) 10 Schizoaffective disorder-bipolar type http://www.ebi.ac.uk/efo/EFO_0009965 GCST008117 Genome-wide genotyping array 32335 2019-07-09 31043756 Stahl EA 2019-05-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31043756 Genome-wide association study identifies 30 loci associated with bipolar disorder. Bipolar disorder 20,352 European ancestry cases, 31,358 European ancestry controls 9,412 European ancestry cases, 137,760 European ancestry controls NR [9372253] (imputed) 184 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST008103 Genome-wide genotyping array 51710 2020-07-22 32266521 Justice CM 2020-04-07 Hum Genet www.ncbi.nlm.nih.gov/pubmed/32266521 A genome-wide association study implicates the BMP7 locus as a risk factor for nonsyndromic metopic craniosynostosis. Midline nonsyndromic craniosynostosis 345 European ancestry trios NA Illumina [306233] 2 Isolated craniosynostosis http://www.orpha.net/ORDO/Orphanet_139390 GCST010297 Genome-wide genotyping array 345 2020-07-22 32266521 Justice CM 2020-04-07 Hum Genet www.ncbi.nlm.nih.gov/pubmed/32266521 A genome-wide association study implicates the BMP7 locus as a risk factor for nonsyndromic metopic craniosynostosis. Metopic nonsyndromic craniosynostosis 215 European ancestry trios 194 European ancestry cases, 333 European ancestry controls Illumina [649669] 3 metopic craniosynostosis http://www.ebi.ac.uk/efo/EFO_0008511 GCST010298 Genome-wide genotyping array 215 2020-07-28 32386560 Ramirez J 2020-04-29 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32386560 Common Genetic Variants Modulate the Electrocardiographic Tpeak-to-Tend Interval. TPE interval (resting) 71,338 European ancestry individuals NA Affymetrix [~ 9000000] (imputed) 62 TPE interval measurement http://www.ebi.ac.uk/efo/EFO_0004644 GCST010346 Genome-wide genotyping array 71338 2020-07-28 32386560 Ramirez J 2020-04-29 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32386560 Common Genetic Variants Modulate the Electrocardiographic Tpeak-to-Tend Interval. TPE interval (response to exercise) 51,897 European ancestry individuals NA Affymetrix [~ 9000000] (imputed) 3 TPE interval measurement, response to exercise http://www.ebi.ac.uk/efo/EFO_0004644, http://www.ebi.ac.uk/efo/EFO_0007768 GCST010345 Genome-wide genotyping array 51897 2020-07-28 32386560 Ramirez J 2020-04-29 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32386560 Common Genetic Variants Modulate the Electrocardiographic Tpeak-to-Tend Interval. TPE interval (recovery after exercise) 51,503 European ancestry individuals NA Affymetrix [~ 9000000] (imputed) 3 TPE interval measurement, response to exercise http://www.ebi.ac.uk/efo/EFO_0004644, http://www.ebi.ac.uk/efo/EFO_0007768 GCST010344 Genome-wide genotyping array 51503 2020-12-06 29930801 Yamada Y 2018-05-29 Biomed Rep www.ncbi.nlm.nih.gov/pubmed/29930801 Identification of nine genes as novel susceptibility loci for early-onset ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage. Ischemic stroke 450 Japanese ancestry cases, 5,774 Japanese ancestry controls NA Illumina [31245] 10 Ischemic stroke http://purl.obolibrary.org/obo/HP_0002140 GCST010836 Exome genotyping array 6224 2020-12-06 29930801 Yamada Y 2018-05-29 Biomed Rep www.ncbi.nlm.nih.gov/pubmed/29930801 Identification of nine genes as novel susceptibility loci for early-onset ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage. Intracerebral hemorrhage 261 Japanese ancestry intracerebral hemorrhage cases, 176 Japanese ancestry subarachnoid hemorrhage cases, 5,742 Japanese ancestry controls NA Illumina [30970] 3 intracerebral hemorrhage http://www.ebi.ac.uk/efo/EFO_0005669 GCST010837 Exome genotyping array 6179 2021-06-02 31913414 Bahrami S 2020-01-08 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/31913414 Shared Genetic Loci Between Body Mass Index and Major Psychiatric Disorders: A Genome-wide Association Study. Major psychiatric disorders or BMI (pleiotropy) at least 34,241 schizophrenia cases, 20,352 bipolar disorder cases, up to 135,458 major depression cases, 795,640 individuals with BMI measurements, 421,863 controls NA NR [NR] 0 unipolar depression, schizophrenia, bipolar disorder, body mass index http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0000289, http://www.ebi.ac.uk/efo/EFO_0004340 GCST011777 Genome-wide genotyping array 1407554 2020-06-16 31904872 Chou WC 2020-01-06 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/31904872 A Functional Variant Near XCL1 Gene Improves Breast Cancer Survival via Promoting Cancer Immunity. Survival in breast cancer (estrogen-receptor positive) 953 Taiwanese individuals NA Affymetrix [632566] (imputed) 4 survival time http://www.ebi.ac.uk/efo/EFO_0000714 GCST010079 Genome-wide genotyping array 953 2020-06-05 32084209 Seo JY 2020-02-21 PLoS One www.ncbi.nlm.nih.gov/pubmed/32084209 A genome-wide association study on liver enzymes in Korean population. Bilirubin levels 4,457 Korean ancestry individuals 2,031 Korean ancestry individuals Affymetrix [546738] 4 bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004570 GCST010048 Genome-wide genotyping array 4457 2020-06-05 32084209 Seo JY 2020-02-21 PLoS One www.ncbi.nlm.nih.gov/pubmed/32084209 A genome-wide association study on liver enzymes in Korean population. Serum alkaline phosphatase levels 4,457 Korean ancestry individuals 2,031 Korean ancestry individuals Affymetrix [546738] 1 alkaline phosphatase measurement http://www.ebi.ac.uk/efo/EFO_0004533 GCST010047 Genome-wide genotyping array 4457 2020-06-05 32084209 Seo JY 2020-02-21 PLoS One www.ncbi.nlm.nih.gov/pubmed/32084209 A genome-wide association study on liver enzymes in Korean population. Alanine transaminase levels 4,457 Korean ancestry individuals 2,031 Korean ancestry individuals Affymetrix [546738] 0 serum alanine aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004735 GCST010046 Genome-wide genotyping array 4457 2020-06-05 32084209 Seo JY 2020-02-21 PLoS One www.ncbi.nlm.nih.gov/pubmed/32084209 A genome-wide association study on liver enzymes in Korean population. Gamma glutamyl transferase levels 4,457 Korean ancestry individuals 2,031 Korean ancestry individuals Affymetrix [546738] 1 serum gamma-glutamyl transferase measurement http://www.ebi.ac.uk/efo/EFO_0004532 GCST010045 Genome-wide genotyping array 4457 2020-04-17 31960908 Nag A 2020-01-21 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31960908 Genome-wide scan identifies novel genetic loci regulating salivary metabolite levels. Salivary metabolite levels 1,419 European ancestry individuals 1,000 European ancestry individuals Illumina [9600000] (imputed) 4 salivary metabolite measurement http://www.ebi.ac.uk/efo/EFO_0010637 GCST009885 Genome-wide genotyping array 1419 2020-04-15 32066696 Dalvie S 2020-01-27 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32066696 Genomic influences on self-reported childhood maltreatment. Childhood maltreatment 124,711 European ancestry individuals 26,290 European ancestry individuals Affymetrix, Illumina [at least 800000] (imputed) 3 childhood trauma measurement http://www.ebi.ac.uk/efo/EFO_0007979 GCST009816 Genome-wide genotyping array 124711 2020-05-29 32152699 Nudel R 2020-03-09 Hum Genet www.ncbi.nlm.nih.gov/pubmed/32152699 A large population-based investigation into the genetics of susceptibility to gastrointestinal infections and the link between gastrointestinal infections and mental illness. Gastrointestinal infection 7,197 Danish ancestry cases, 37,062 Danish ancestry controls NA Illumina [11600722] (imputed) 20 digestive system infectious disease http://purl.obolibrary.org/obo/MONDO_0043424 GCST010008 Genome-wide genotyping array 44259 2020-07-09 32157568 Strupp M 2020-03-10 Cerebellum www.ncbi.nlm.nih.gov/pubmed/32157568 A Variation in FGF14 Is Associated with Downbeat Nystagmus in a Genome-Wide Association Study. Idiopathic downbeat nystagmus 106 European ancestry cases, 2,609 European ancestry controls NA Illumina [7759885] (imputed) 16 Nystagmus http://purl.obolibrary.org/obo/HP_0000639 GCST010172 Genome-wide genotyping array 2715 2020-01-15 31097437 Plotnikov D 2019-05-16 Br J Ophthalmol www.ncbi.nlm.nih.gov/pubmed/31097437 Association between birth weight and refractive error in adulthood: a Mendelian randomisation study. Birth weight 188,039 European ancestry individuals NA Affymetrix [up to 10400000] (imputed) 73 birth weight http://www.ebi.ac.uk/efo/EFO_0004344 GCST009437 Genome-wide genotyping array 188039 2020-01-15 31097437 Plotnikov D 2019-05-16 Br J Ophthalmol www.ncbi.nlm.nih.gov/pubmed/31097437 Association between birth weight and refractive error in adulthood: a Mendelian randomisation study. Refractive error 139,884 European ancestry individuals NA Affymetrix [up to 10400000] (imputed) 0 refractive error measurement http://www.ebi.ac.uk/efo/EFO_0007814 GCST009436 Genome-wide genotyping array 139884 2020-09-07 32393786 Meddens SFW 2020-05-11 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32393786 Genomic analysis of diet composition finds novel loci and associations with health and lifestyle. Relative fat intake 175,253 European ancestry individuals 93,179 European ancestry individuals Affymetrix [NR] 4 fat intake measurement http://www.ebi.ac.uk/efo/EFO_0010809 GCST010499 Genome-wide genotyping array 175253 2020-09-07 32393786 Meddens SFW 2020-05-11 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32393786 Genomic analysis of diet composition finds novel loci and associations with health and lifestyle. Relative protein intake 175,253 European ancestry individuals 93,179 European ancestry individuals Affymetrix [NR] 5 protein intake measurement http://www.ebi.ac.uk/efo/EFO_0010810 GCST010498 Genome-wide genotyping array 175253 2020-09-07 32393786 Meddens SFW 2020-05-11 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32393786 Genomic analysis of diet composition finds novel loci and associations with health and lifestyle. Relative carbohydrate intake 175,253 European ancestry individuals 93,179 European ancestry individuals Affymetrix [NR] 7 carbohydrate intake measurement http://www.ebi.ac.uk/efo/EFO_0010811 GCST010497 Genome-wide genotyping array 175253 2020-09-07 32393786 Meddens SFW 2020-05-11 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32393786 Genomic analysis of diet composition finds novel loci and associations with health and lifestyle. Relative sugar intake 175,253 European ancestry individuals 59,454 European ancestry individuals Affymetrix [NR] 5 sugar consumption measurement http://www.ebi.ac.uk/efo/EFO_0010158 GCST010496 Genome-wide genotyping array 175253 2020-09-12 32762793 Jang SK 2020-08-07 Psychol Med www.ncbi.nlm.nih.gov/pubmed/32762793 Genetic correlation, pleiotropy, and causal associations between substance use and psychiatric disorder. Substance uses or psychiatric disorders (pleiotropy) Up to 1,232,09 European ancestry individuals with substance use, 53,293 European ancestry ADHD cases, 72,517 European ancestry anorexia cases, 51,710 European ancestry bipolar disorder cases, 173,005 European ancestry major depressive disorder cases, 105,318 European ancestry schizophrenia cases, 1,475,951 European ancestry controls NA NR [NR] 0 anorexia nervosa, major depressive episode, schizophrenia, substance abuse, bipolar disorder, ADHD symptom measurement http://www.ebi.ac.uk/efo/EFO_0004215, http://www.ebi.ac.uk/efo/EFO_0007634, http://www.ebi.ac.uk/efo/EFO_0000692, http://purl.obolibrary.org/obo/MONDO_0002491, http://www.ebi.ac.uk/efo/EFO_0000289, http://www.ebi.ac.uk/efo/EFO_0007860 GCST010542 Genome-wide genotyping array 2055003 2021-03-28 32759990 Carlson JC 2020-08-05 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32759990 Genome-wide association studies in Samoans give insight into the genetic architecture of fasting serum lipid levels. HDL cholesterol levels 2,849 Samoan (founder/genetic isolate) individuals 1,798 Samoan and American Samoan (founder/genetic isolate) individuals Affymetrix [659492] 4 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST011418 Genome-wide genotyping array 2849 2021-03-28 32759990 Carlson JC 2020-08-05 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32759990 Genome-wide association studies in Samoans give insight into the genetic architecture of fasting serum lipid levels. LDL cholesterol levels 2,849 Samoan (founder/genetic isolate) individuals 1,798 Samoan and American Samoan (founder/genetic isolate) individuals Affymetrix [659492] 2 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST011417 Genome-wide genotyping array 2849 2021-03-28 32759990 Carlson JC 2020-08-05 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32759990 Genome-wide association studies in Samoans give insight into the genetic architecture of fasting serum lipid levels. Triglyceride levels 2,849 Samoan (founder/genetic isolate) individuals 1,798 Samoan and American Samoan (founder/genetic isolate) individuals Affymetrix [659492] 2 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST011416 Genome-wide genotyping array 2849 2021-03-28 32759990 Carlson JC 2020-08-05 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32759990 Genome-wide association studies in Samoans give insight into the genetic architecture of fasting serum lipid levels. Total cholesterol levels 2,849 Samoan (founder/genetic isolate) individuals 1,798 Samoan and American Samoan (founder/genetic isolate) individuals Affymetrix [659492] 2 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST011419 Genome-wide genotyping array 2849 2021-03-22 31902292 Kanipakam H 2020-01-17 J Biomol Struct Dyn www.ncbi.nlm.nih.gov/pubmed/31902292 Structural and functional alterations of nitric oxide synthase 3 due to missense variants associate with high-altitude pulmonary edema through dynamic study. High-altitude pulmonary edema 96 Indo-Aryan ancestry cases, 96 Indo-Aryan ancestry controls 200 cases, 200 controls Illumina [NR] 0 high altitude pulmonary edema http://www.ebi.ac.uk/efo/EFO_1002002 GCST011375 Genome-wide genotyping array 192 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_15 (Parasutterella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011574 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_150 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011575 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_16 (Faecalibacterium) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011576 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_163 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011577 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_165 (Porphyromonadaceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011578 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_17 (Parabacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011579 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_173 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011580 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_19 (Bacteria) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011581 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_2 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011582 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_21 (Parasutterella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011583 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_23 (Faecalibacterium) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011584 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_235 (Phascolarctobacterium) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011585 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_24 (Prevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011586 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_257 (Mitsuokella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011587 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_26 (Parasutterella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011588 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_27 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011589 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_277 (Prevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011590 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_3 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011591 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_30 (Roseburia) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011592 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_31 (Prevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011593 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_33 (Holdemanella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011594 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_34 (Ruminococcus) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011595 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_354 (Alloprevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011596 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_38 (Alphaproteobacteria) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011597 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_39 (Proteobacteria) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011598 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Prevotella prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011550 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Prevotellaceae prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011551 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Ruminococcus prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011552 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Sutterella prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011553 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. O_Selenomonadales prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011554 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_1 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011555 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_100 (Ruminococcaceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011556 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_101 (Sutterella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011557 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_102 (Prevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011558 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_105 (Ruminococcaceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011559 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_106 (Ruminococcaceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011560 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_108 (Phascolarctobacterium) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011561 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_109 (Paraprevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011562 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_11 (Parabacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011563 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_113 (Bacteroidales) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011564 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_117 (Ruminococcus) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011565 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_119 (Desulfovibrio) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011566 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_12 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011567 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_126 (Prevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011568 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_13 (Subdoligranulum) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011569 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_130 (Butyrivibrio) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011570 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_137 (Catenibacterium) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011571 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_138 (Oscillibacter) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011572 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_140 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011573 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_30 (Parasutterella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011653 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_8 (Ruminococcaceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011675 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_84 (Prevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011676 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_85 (Alistipes) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011677 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_9 (Alistipes) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011678 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_92 (Ruminococcus) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011679 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_94 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011680 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_98 (Phascolarctobacterium) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011681 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_1 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011682 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_10 (Parabacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011683 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_11 (Lachnospiraceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011684 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_12 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011685 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_13 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011686 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_14 (Lachnospiraceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011687 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_15 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011688 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_16 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011689 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_17 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011690 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_18 (Prevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011691 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_19 (Prevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011692 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_2 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011693 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. C_Actinobacteria abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011301 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. C_Alphaproteobacteria abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011302 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. C_Bacteroidia abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011303 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. C_Betaproteobacteria abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011304 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. C_Clostridia abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011305 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. C_Erysipelotrichia abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011306 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_26 (Parasutterella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011649 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_271 (Prevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011650 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_298 (Phascolarctobacterium) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011651 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_3 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011652 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_32 (Prevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011654 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_34 (Holdemanella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011655 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_35 (Ruminococcus) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011656 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_39 (Alphaproteobacteria) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011657 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_4 (Alistipes) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011658 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_40 (Proteobacteria) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011659 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_45 (Faecalibacterium) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011660 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_47 (Prevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011661 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_5 (Sutterella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011662 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_53 (Aestuariispira) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011663 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_54 (Holdemanella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011664 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_55 (Barnesiella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011665 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_558 (Bacteroidales) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011666 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_58 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011667 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_59 (Prevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011668 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_6 (Sutterella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011669 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_62 (Ruminococcaceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011670 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_65 (Sutterellaceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011671 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_7 (Lachnospiraceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011672 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_72 (Parabacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011673 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_78 (Clostridiales) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011674 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_4 (Alistipes) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011599 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_46 (Lachnospiraceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011600 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_5 (Sutterella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011601 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_50 (Aestuariispira) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011602 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_51 (Barnesiella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011603 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_53 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011604 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_56 (Ruminococcaceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011605 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_58 (Sutterellaceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011606 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_6 (Sutterella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011607 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_65 (Parabacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011608 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_69 (Clostridiales) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011609 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_7 (Lachnospiraceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011610 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_73 (Prevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011611 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_74 (Alistipes) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011612 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_8 (Ruminococcaceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011613 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_80 (Ruminococcus) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011614 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_82 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011615 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_86 (Phascolarctobacterium) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011616 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_9 (Alistipes) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011617 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_95 (Cytophagales) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011618 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_97 (Clostridiales) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011619 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_1 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011620 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_106 (Barnesiella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011621 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_108 (Cytophagales) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011622 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_11 (Parabacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011623 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_47 (Parasutterella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011525 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_48 (Sutterella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011526 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_49 (Parasutterella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011527 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_5 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011528 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_6 (Subdoligranulum) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011529 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_7 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011530 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_8 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011531 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_9 (Alistipes) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011532 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. C_Alphaproteobacteria prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011533 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. C_Negativicutes prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011534 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. F_Acidaminococcaceae prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011535 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. F_Prevotellaceae prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011536 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Alloprevotella prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011537 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Alphaproteobacteria prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011538 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Bacteroidales prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011539 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Bacteroidetes prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011540 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Barnesiella prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011541 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Catenibacterium prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011542 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Coprococcus prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011543 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Holdemanella prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011544 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Parabacteroides prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011545 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Paraprevotella prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011546 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Parasutterella prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011547 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Phascolarctobacterium prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011548 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Porphyromonadaceae prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011549 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_110 (Clostridiales) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011624 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_116 (Sutterella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011625 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_12 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011626 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_120 (Ruminococcaceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011627 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_121 (Ruminococcaceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011628 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_123 (Phascolarctobacterium) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011629 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_124 (Paraprevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011630 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_13 (Subdoligranulum) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011631 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_132 (Bacteroidales) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011632 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_137 (Ruminococcus) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011633 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_140 (Desulfovibrio) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011634 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_150 (Prevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011635 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_155 (Butyrivibrio) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011636 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_157 (Barnesiella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011637 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_16 (Faecalibacterium) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011638 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_166 (Prevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011639 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_17 (Parabacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011640 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_171 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011641 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_19 (Bacteria) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011642 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_197 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011643 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_2 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011644 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_21 (Parasutterella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011645 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_211 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011646 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_23 (Faecalibacterium) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011647 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_24 (Prevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011648 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_23 (Barnesiella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011500 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_24 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011501 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_25 (Sutterella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011502 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_26 (Phascolarctobacterium) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011503 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_27 (Ruminococcaceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011504 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_28 (Holdemanella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011505 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_29 (Barnesiella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011506 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_3 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011507 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_30 (Paraprevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011508 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_31 (Ruminococcus) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011509 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_32 (Ruminococcaceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011510 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_33 (Paraprevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011511 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_34 (Phascolarctobacterium) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011512 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_35 (Alphaproteobacteria) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011513 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_36 (Aestuariispira) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011514 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_37 (Ruminococcaceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011515 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_38 (Ruminococcus) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011516 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_39 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011517 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_4 (Alistipes) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011518 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_41 (Barnesiella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011519 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_42 (Alphaproteobacteria) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011520 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_43 (Parasutterella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011521 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_44 (Parasutterella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011522 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_45 (Clostridiales) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011523 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_46 (Sutterella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011524 Genome-wide genotyping array 8956 2020-03-03 31959993 Craig JE 2020-01-20 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31959993 Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression. Vertical cup-disc ratio (adjusted for vertical disc diameter) 67,040 British ancestry individuals NA Affymetrix [at least 8002429] (imputed) 100 cup-to-disc ratio measurement http://www.ebi.ac.uk/efo/EFO_0006939 GCST009723 Genome-wide genotyping array 67040 2020-03-03 31959993 Craig JE 2020-01-20 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31959993 Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression. Vertical cup-disc ratio (multi-trait analysis) 90,939 European ancestry individuals NA Affymetrix, Illumina [8002429] (imputed) 107 cup-to-disc ratio measurement http://www.ebi.ac.uk/efo/EFO_0006939 GCST009724 Genome-wide genotyping array 90939 2020-03-03 31959993 Craig JE 2020-01-20 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31959993 Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression. Intraocular pressure 133,492 European ancestry individuals NA Affymetrix, Illumina [8002429] (imputed) 95 intraocular pressure measurement http://www.ebi.ac.uk/efo/EFO_0004695 GCST009725 Genome-wide genotyping array 133492 2020-03-03 31959993 Craig JE 2020-01-20 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31959993 Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression. Glaucoma 7,947 British ancestry cases, 119,318 British ancestry controls NA Affymetrix [at least 8002429] (imputed) 39 glaucoma http://www.ebi.ac.uk/efo/EFO_0000516 GCST009726 Genome-wide genotyping array 127265 2020-03-03 31959993 Craig JE 2020-01-20 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31959993 Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression. Glaucoma (multi-trait analysis) 133,492 European ancestry individuals with intraocular pressure measurements, 90,939 European ancestry individuals with vertical cup-disc ratio measurements, 7,947 British ancestry glaucoma cases, 119,318 British ancestry controls 6,924 European ancestry glaucoma cases, 40,230 European ancestry controls Affymetrix, Illumina [8002429] (imputed) 20 glaucoma http://www.ebi.ac.uk/efo/EFO_0000516 GCST009722 Genome-wide genotyping array 351696 2020-06-11 31902109 Li D 2020-01-04 Genes Genomics www.ncbi.nlm.nih.gov/pubmed/31902109 Progressive effects of single-nucleotide polymorphisms on 16 phenotypic traits based on longitudinal data. Hematological and biochemical traits up to 6,843 Korean ancestry individuals NA Affymetrix [305158] 9 hemoglobin measurement, diastolic blood pressure, systolic blood pressure, hemoglobin A1 measurement, fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004509, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0007629, http://www.ebi.ac.uk/efo/EFO_0004465 GCST010062 Genome-wide genotyping array 6843 2020-06-11 31902109 Li D 2020-01-04 Genes Genomics www.ncbi.nlm.nih.gov/pubmed/31902109 Progressive effects of single-nucleotide polymorphisms on 16 phenotypic traits based on longitudinal data. Lung function up to 4,291 Korean ancestry individuals NA Affymetrix [305158] 1 pulmonary function measurement http://www.ebi.ac.uk/efo/EFO_0003892 GCST010061 Genome-wide genotyping array 4291 2020-06-11 31902109 Li D 2020-01-04 Genes Genomics www.ncbi.nlm.nih.gov/pubmed/31902109 Progressive effects of single-nucleotide polymorphisms on 16 phenotypic traits based on longitudinal data. Cholesterol 6,840 Korean ancestry individuals NA Affymetrix [305158] 14 total cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0004611, http://www.ebi.ac.uk/efo/EFO_0004612 GCST010060 Genome-wide genotyping array 6840 2020-06-11 31902109 Li D 2020-01-04 Genes Genomics www.ncbi.nlm.nih.gov/pubmed/31902109 Progressive effects of single-nucleotide polymorphisms on 16 phenotypic traits based on longitudinal data. Physiological traits up to 6,835 Korean ancestry individuals NA Affymetrix [305158] 5 waist circumference, body weight, body mass index, body height http://www.ebi.ac.uk/efo/EFO_0004342, http://www.ebi.ac.uk/efo/EFO_0004338, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004339 GCST010063 Genome-wide genotyping array 6835 2020-06-11 31902109 Li D 2020-01-04 Genes Genomics www.ncbi.nlm.nih.gov/pubmed/31902109 Progressive effects of single-nucleotide polymorphisms on 16 phenotypic traits based on longitudinal data. Physiological traits up to 6,835 Korean ancestry individuals NA Affymetrix [305158] 10 waist circumference, longitudinal BMI measurement, body weight, body height http://www.ebi.ac.uk/efo/EFO_0004342, http://www.ebi.ac.uk/efo/EFO_0005937, http://www.ebi.ac.uk/efo/EFO_0004338, http://www.ebi.ac.uk/efo/EFO_0004339 GCST010059 Genome-wide genotyping array 6835 2020-06-11 31902109 Li D 2020-01-04 Genes Genomics www.ncbi.nlm.nih.gov/pubmed/31902109 Progressive effects of single-nucleotide polymorphisms on 16 phenotypic traits based on longitudinal data. Hematological and biochemical traits up to 6,843 Korean ancestry individuals NA Affymetrix [305158] 2 hemoglobin measurement, diastolic blood pressure change measurement, hemoglobin A1 measurement, systolic blood pressure change measurement, fasting blood glucose change measurement http://www.ebi.ac.uk/efo/EFO_0004509, http://www.ebi.ac.uk/efo/EFO_0006945, http://www.ebi.ac.uk/efo/EFO_0007629, http://www.ebi.ac.uk/efo/EFO_0006944, http://www.ebi.ac.uk/efo/EFO_0010120 GCST010058 Genome-wide genotyping array 6843 2020-06-11 31902109 Li D 2020-01-04 Genes Genomics www.ncbi.nlm.nih.gov/pubmed/31902109 Progressive effects of single-nucleotide polymorphisms on 16 phenotypic traits based on longitudinal data. Lung function up to 4,291 Korean ancestry individuals NA Affymetrix [305158] 9 pulmonary function measurement http://www.ebi.ac.uk/efo/EFO_0003892 GCST010057 Genome-wide genotyping array 4291 2020-06-11 31902109 Li D 2020-01-04 Genes Genomics www.ncbi.nlm.nih.gov/pubmed/31902109 Progressive effects of single-nucleotide polymorphisms on 16 phenotypic traits based on longitudinal data. Cholesterol 6,840 Korean ancestry individuals NA Affymetrix [305158] 2 HDL cholesterol change measurement, triglyceride change measurement, LDL cholesterol change measurement, total cholesterol change measurement http://www.ebi.ac.uk/efo/EFO_0007805, http://www.ebi.ac.uk/efo/EFO_0007681, http://www.ebi.ac.uk/efo/EFO_0007804, http://www.ebi.ac.uk/efo/EFO_0007806 GCST010056 Genome-wide genotyping array 6840 2020-02-21 31869403 Kowalski MH 2019-12-23 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31869403 Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations. Hematocrit 14,735 African American individuals, 6,762 African ancestry individuals, 21,684 Hispanic/Latino individuals 7,050 African American individuals Affymetrix, Illumina [up to 35800000] (imputed) 5 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST009682 Genome-wide genotyping array 43181 2020-02-21 31869403 Kowalski MH 2019-12-23 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31869403 Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations. Hemoglobin levels 14,739 African American individuals, 6,762 African ancestry individuals, 21,686 Hispanic/Latino individuals 7,037 African American individuals Affymetrix, Illumina [up to 35800000] (imputed) 10 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST009681 Genome-wide genotyping array 43187 2020-02-21 31869403 Kowalski MH 2019-12-23 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31869403 Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations. White blood cell count 14,743 African American individuals, 6,762 African ancestry individuals, 21,034 Hispanic/Latino individuals 6,743 African American individuals Affymetrix, Illumina [up to 35800000] (imputed) 6 leukocyte count http://www.ebi.ac.uk/efo/EFO_0004308 GCST009683 Genome-wide genotyping array 42539 2020-07-08 32066700 Zhang R 2020-02-05 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32066700 Genome-wide study of immune biomarkers in cerebrospinal fluid and serum from patients with bipolar disorder and controls. Serum immune biomarker levels 184 Scandinavian ancestry bipolar disorder cases, 107 Scandinavian ancestry controls NA Affymetrix, Illumina [> 5000000] (imputed) 46 inflammatory biomarker measurement http://www.ebi.ac.uk/efo/EFO_0004872 GCST010146 Genome-wide genotyping array 291 2020-07-08 32066700 Zhang R 2020-02-05 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32066700 Genome-wide study of immune biomarkers in cerebrospinal fluid and serum from patients with bipolar disorder and controls. Cerebrospinal fluid immune biomarker levels 114 Scandinavian ancestry bipolar disorder cases, 83 Scandinavian ancestry controls NA Affymetrix, Illumina [> 5600000] (imputed) 15 cerebrospinal fluid biomarker measurement http://www.ebi.ac.uk/efo/EFO_0006794 GCST010145 Genome-wide genotyping array 197 2020-04-15 32063569 Alemany-Navarro M 2020-01-29 J Affect Disord www.ncbi.nlm.nih.gov/pubmed/32063569 Exploring genetic variants in obsessive compulsive disorder severity: A GWAS approach. Obsessive compulsive disorder severity 376 Spanish ancestry individuals NA Illumina [338357] 5 obsessive-compulsive disorder, obsessive-compulsive symptom measurement http://www.ebi.ac.uk/efo/EFO_0004242, http://www.ebi.ac.uk/efo/EFO_0007802 GCST009818 Genome-wide genotyping array 376 2020-04-15 32063569 Alemany-Navarro M 2020-01-29 J Affect Disord www.ncbi.nlm.nih.gov/pubmed/32063569 Exploring genetic variants in obsessive compulsive disorder severity: A GWAS approach. Compulsion score in obsessive compulsive disorder 376 Spanish ancestry individuals NA Illumina [338357] 4 obsessive-compulsive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007802 GCST009819 Genome-wide genotyping array 376 2020-04-15 32063569 Alemany-Navarro M 2020-01-29 J Affect Disord www.ncbi.nlm.nih.gov/pubmed/32063569 Exploring genetic variants in obsessive compulsive disorder severity: A GWAS approach. Obsession score in obsessive compulsive disorder 376 Spanish ancestry individuals NA Illumina [338357] 1 obsessive-compulsive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007802 GCST009820 Genome-wide genotyping array 376 2020-10-15 32080893 Divers J 2020-02-20 Clin Transplant www.ncbi.nlm.nih.gov/pubmed/32080893 GWAS for time to failure of kidney transplants from African American deceased donors. Graft survival time in renal transplantation (donor effect) 532 African American donors 250 African American donors Illumina [> 13000000] (imputed) 4 renal transplant outcome measurement, donor genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0005199, http://www.ebi.ac.uk/efo/EFO_0007892 GCST010683 Genome-wide genotyping array 532 2020-10-15 32080893 Divers J 2020-02-20 Clin Transplant www.ncbi.nlm.nih.gov/pubmed/32080893 GWAS for time to failure of kidney transplants from African American deceased donors. Graft survival time in renal transplantation (donor effect) x APOL1 genotype interaction 532 African American donors 250 African American donors Illumina [> 13000000] (imputed) 6 renal transplant outcome measurement, APOL1 risk genotype carrier status, donor genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0005199, http://www.ebi.ac.uk/efo/EFO_0009324, http://www.ebi.ac.uk/efo/EFO_0007892 GCST010682 Genome-wide genotyping array 532 2020-07-21 32080354 Rasmussen ER 2020-02-21 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/32080354 Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment. Angioedema in response to angiotensin-converting enzyme inhibitor and/or angiotensin receptor blocker 172 European ancestry cases, 1 case, 4,890 European ancestry controls NA Illumina [7585599] (imputed) 19 response to angiotensin-converting enzyme inhibitor, response to angiotensin receptor blocker, angioedema http://www.ebi.ac.uk/efo/EFO_0005325, http://www.ebi.ac.uk/efo/EFO_0010735, http://www.ebi.ac.uk/efo/EFO_0005532 GCST010247 Genome-wide genotyping array 5063 2020-07-21 32080354 Rasmussen ER 2020-02-21 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/32080354 Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment. Angioedema in response to angiotensin-converting enzyme inhibitor and/or angiotensin receptor blocker 172 European ancestry cases, 1 case, 1,345 European ancestry treated controls 347 European ancestry cases, 66 African ancestry cases, 440 European ancestry treated controls, 157 African ancestry treated controls Illumina [7585599] (imputed) 0 response to angiotensin-converting enzyme inhibitor, response to angiotensin receptor blocker, angioedema http://www.ebi.ac.uk/efo/EFO_0005325, http://www.ebi.ac.uk/efo/EFO_0010735, http://www.ebi.ac.uk/efo/EFO_0005532 GCST010246 Genome-wide genotyping array 1518 2020-01-15 31095298 Huang M 2019-05-16 Bioinformatics www.ncbi.nlm.nih.gov/pubmed/31095298 Incorporating spatial-anatomical similarity into the VGWAS framework for AD biomarker detection. Voxel-wise structural brain imaging measurements in Alzheimer’s disease 708 European ancestry individuals NA Illumina [501584] 15 neuroimaging measurement http://www.ebi.ac.uk/efo/EFO_0004346 GCST009438 Genome-wide genotyping array 708 2021-01-26 32201043 Smeland OB 2020-02-08 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32201043 Genome-wide Association Analysis of Parkinson's Disease and Schizophrenia Reveals Shared Genetic Architecture and Identifies Novel Risk Loci. Parkinson's disease 20,184 European ancestry cases, 397,324 European ancestry controls NA Illumina [NR] 55 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST010991 Genome-wide genotyping array 417508 2021-01-26 32201043 Smeland OB 2020-02-08 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32201043 Genome-wide Association Analysis of Parkinson's Disease and Schizophrenia Reveals Shared Genetic Architecture and Identifies Novel Risk Loci. Parkinson's disease or schizophrenia 34,875 European ancestry schizophrenia cases, 20,184 European ancestry Parkinson's disease cases, 440,781 European ancestry controls NA Illumina [NR] 0 Parkinson's disease, schizophrenia http://www.ebi.ac.uk/efo/EFO_0002508, http://www.ebi.ac.uk/efo/EFO_0000692 GCST010990 Genome-wide genotyping array 495840 2020-01-09 31089300 Matoba N 2019-03-25 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31089300 GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture. Smoking initiation (ever regular vs never regular) 83,830 Japanese ancestry ever smokers, 81,626 Japanese ancestry never smokers NA Illumina [5961480] (imputed) 1 smoking status measurement http://www.ebi.ac.uk/efo/EFO_0006527 GCST009403 Genome-wide genotyping array 165456 2020-01-09 31089300 Matoba N 2019-03-25 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31089300 GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture. Smoking initiation (ever regular vs never regular) 67,773 Japanese ancestry ever smoker males, 21,905 Japanese ancestry never smoker males NA Illumina [6108828] (imputed) 2 smoking status measurement http://www.ebi.ac.uk/efo/EFO_0006527 GCST009399 Genome-wide genotyping array 89678 2020-01-09 31089300 Matoba N 2019-03-25 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31089300 GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture. Smoking initiation (ever regular vs never regular) 16,077 Japanese ancestry ever smoker females, 59,721 Japanese ancestry never smoker females NA Illumina [6108828] (imputed) 0 smoking status measurement http://www.ebi.ac.uk/efo/EFO_0006527 GCST009402 Genome-wide genotyping array 75798 2020-01-09 31089300 Matoba N 2019-03-25 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31089300 GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture. Smoking cessation (former vs current smokers) 43,163 Japanese ancestry former smokers, 32,884 Japanese ancestry current smokers NA Illumina [5961480] (imputed) 0 smoking status measurement http://www.ebi.ac.uk/efo/EFO_0006527 GCST009400 Genome-wide genotyping array 76047 2020-01-09 31089300 Matoba N 2019-03-25 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31089300 GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture. Smoking cessation (former vs current smokers) 36,787 Japanese ancestry former smoker males, 24,909 Japanese ancestry current smoker males NA Illumina [6108828] (imputed) 0 smoking status measurement http://www.ebi.ac.uk/efo/EFO_0006527 GCST009401 Genome-wide genotyping array 61696 2020-01-09 31089300 Matoba N 2019-03-25 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31089300 GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture. Smoking cessation (former vs current smokers) 6,376 Japanese ancestry former smoker females, 7,975 Japanese ancestry current smoker females NA Illumina [6108828] (imputed) 0 smoking status measurement http://www.ebi.ac.uk/efo/EFO_0006527 GCST009398 Genome-wide genotyping array 14351 2020-01-09 31089300 Matoba N 2019-03-25 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31089300 GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture. Smoking behaviour (cigarettes smoked per day) 72,655 Japanese ancestry individuals NA Illumina [5961480] (imputed) 6 cigarettes per day measurement http://www.ebi.ac.uk/efo/EFO_0006525 GCST009405 Genome-wide genotyping array 72655 2020-01-09 31089300 Matoba N 2019-03-25 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31089300 GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture. Smoking behaviour (cigarettes smoked per day) 13,871 Japanese ancestry females NA Illumina [6108828] (imputed) 1 cigarettes per day measurement http://www.ebi.ac.uk/efo/EFO_0006525 GCST009406 Genome-wide genotyping array 13871 2020-01-09 31089300 Matoba N 2019-03-25 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31089300 GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture. Smoking behaviour (cigarettes smoked per day) 58,784 Japanese ancestry males NA Illumina [6108828] (imputed) 5 cigarettes per day measurement http://www.ebi.ac.uk/efo/EFO_0006525 GCST009407 Genome-wide genotyping array 58784 2020-01-09 31089300 Matoba N 2019-03-25 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31089300 GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture. Age of smoking initiation 30,418 Japanese ancestry individuals NA Illumina [5961480] (imputed) 0 age at onset, smoking initiation http://www.ebi.ac.uk/efo/EFO_0004847, http://www.ebi.ac.uk/efo/EFO_0005670 GCST009408 Genome-wide genotyping array 30418 2020-01-09 31089300 Matoba N 2019-03-25 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31089300 GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture. Age of smoking initiation 7,379 Japanese ancestry females NA Illumina [6108828] (imputed) 1 age at onset, smoking initiation http://www.ebi.ac.uk/efo/EFO_0004847, http://www.ebi.ac.uk/efo/EFO_0005670 GCST009409 Genome-wide genotyping array 7379 2020-01-09 31089300 Matoba N 2019-03-25 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31089300 GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture. Age of smoking initiation 23,039 Japanese ancestry males NA Illumina [6108828] (imputed) 0 age at onset, smoking initiation http://www.ebi.ac.uk/efo/EFO_0004847, http://www.ebi.ac.uk/efo/EFO_0005670 GCST009410 Genome-wide genotyping array 23039 2020-01-22 24777453 Auer PL 2014-04-28 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24777453 Rare and low-frequency coding variants in CXCR2 and other genes are associated with hematological traits. Platelet count 24,814 European ancestry individuals 6,526 European ancestry individuals Illumina [183585] 4 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST009465 Exome genotyping array [Exome array] 24814 2020-01-22 24777453 Auer PL 2014-04-28 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24777453 Rare and low-frequency coding variants in CXCR2 and other genes are associated with hematological traits. Hematocrit 24,814 European ancestry individuals 6,526 European ancestry individuals Illumina [183585] 2 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST009466 Exome genotyping array [Exome array] 24814 2020-01-22 24777453 Auer PL 2014-04-28 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24777453 Rare and low-frequency coding variants in CXCR2 and other genes are associated with hematological traits. Hemoglobin levels 24,814 European ancestry individuals 6,526 European ancestry individuals Illumina [183585] 4 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST009467 Exome genotyping array [Exome array] 24814 2020-01-22 24777453 Auer PL 2014-04-28 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24777453 Rare and low-frequency coding variants in CXCR2 and other genes are associated with hematological traits. White blood cell count 24,814 European ancestry individuals 6,526 European ancestry individuals Illumina [183585] 1 leukocyte count http://www.ebi.ac.uk/efo/EFO_0004308 GCST009468 Exome genotyping array [Exome array] 24814 2020-06-06 31178129 Spracklen CN 2019-06-06 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31178129 Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology. Adiponectin levels up to 60,465 European ancestry individuals, up to 2,568 East Asian ancestry individuals, up to 3,271 African American individuals, up to 1,435 Hispanic individuals NA Illumina [265780] 20 adiponectin measurement http://www.ebi.ac.uk/efo/EFO_0004502 GCST010050 Exome genotyping array [Exome array] 67739 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_16 (Faecalibacterium) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011375 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. O_Coriobacteriales abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011351 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. O_Erysipelotrichales abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011352 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. O_Selenomonadales abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011353 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_17 (Parabacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011378 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_100 (Ruminococcaceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011355 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_19 (Bacteria) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011380 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_102 (Prevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011357 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_105 (Ruminococcaceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011358 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_106 (Ruminococcaceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011359 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_23 (Faecalibacterium) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011383 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_109 (Paraprevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011361 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_24 (Prevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011385 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_257 (Mitsuokella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011386 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_117 (Ruminococcus) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011364 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_119 (Desulfovibrio) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011365 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_12 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011366 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_3 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011390 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_13 (Subdoligranulum) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011368 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_130 (Butyrivibrio) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011369 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_31 (Prevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011392 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_138 (Oscillibacter) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011371 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_140 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011372 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_34 (Ruminococcus) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011394 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_354 (Alloprevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011395 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_38 (Alphaproteobacteria) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011396 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_39 (Proteobacteria) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011397 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_4 (Alistipes) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011398 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_46 (Lachnospiraceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011399 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_5 (Sutterella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011400 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_120 (Ruminococcaceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011426 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_51 (Barnesiella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011402 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_123 (Phascolarctobacterium) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011428 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_124 (Paraprevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011429 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_56 (Ruminococcaceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011404 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_132 (Bacteroidales) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011431 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_6 (Sutterella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011406 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_140 (Desulfovibrio) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011433 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_69 (Clostridiales) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011408 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_155 (Butyrivibrio) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011435 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_157 (Barnesiella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011436 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_16 (Faecalibacterium) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011437 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_166 (Prevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011438 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_8 (Ruminococcaceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011412 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_171 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011440 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_82 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011414 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_197 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011442 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_95 (Cytophagales) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011417 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_21 (Parasutterella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011444 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_1 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011419 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_23 (Faecalibacterium) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011446 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. P_Actinobacteria abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011481 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_24 (Prevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011447 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_110 (Clostridiales) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011423 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_116 (Sutterella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011424 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_12 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011425 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_50 (Aestuariispira) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011401 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_121 (Ruminococcaceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011427 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_53 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011403 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_13 (Subdoligranulum) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011430 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_58 (Sutterellaceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011405 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_137 (Ruminococcus) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011432 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_65 (Parabacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011407 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_150 (Prevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011434 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_7 (Lachnospiraceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011409 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_73 (Prevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011410 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_74 (Alistipes) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011411 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_17 (Parabacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011439 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_80 (Ruminococcus) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011413 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_19 (Bacteria) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011441 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_86 (Phascolarctobacterium) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011415 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_9 (Alistipes) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011416 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_2 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011443 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_97 (Clostridiales) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011418 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_211 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011445 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_106 (Barnesiella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011420 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_108 (Cytophagales) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011421 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_11 (Parabacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011422 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_26 (Parasutterella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011448 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_8 (Ruminococcaceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011474 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_84 (Prevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011475 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_85 (Alistipes) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011476 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_9 (Alistipes) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011477 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_92 (Ruminococcus) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011478 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_94 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011479 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_98 (Phascolarctobacterium) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011480 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. P_Bacteroidetes abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011482 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. P_Firmicutes abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011483 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. P_Proteobacteria abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011484 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_1 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011485 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_10 (Parabacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011486 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_11 (Lachnospiraceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011487 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_12 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011488 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_13 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011489 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_14 (Lachnospiraceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011490 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_15 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011491 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_16 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011492 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_17 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011493 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_18 (Prevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011494 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_19 (Prevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011495 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_2 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011496 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_20 (Phascolarctobacterium) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011497 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_21 (Ruminococcaceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011498 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_22 (Sutterella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011499 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_271 (Prevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011449 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_298 (Phascolarctobacterium) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011450 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_3 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011451 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_30 (Parasutterella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011452 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_32 (Prevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011453 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_34 (Holdemanella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011454 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_35 (Ruminococcus) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011455 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_39 (Alphaproteobacteria) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011456 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_4 (Alistipes) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011457 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_40 (Proteobacteria) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011458 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_45 (Faecalibacterium) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011459 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_47 (Prevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011460 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_5 (Sutterella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011461 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_53 (Aestuariispira) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011462 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_54 (Holdemanella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011463 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_55 (Barnesiella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011464 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_558 (Bacteroidales) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011465 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_58 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011466 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_59 (Prevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011467 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_6 (Sutterella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011468 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_62 (Ruminococcaceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011469 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_65 (Sutterellaceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011470 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_7 (Lachnospiraceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011471 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_72 (Parabacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011472 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU99_78 (Clostridiales) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011473 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. O_Clostridiales abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011350 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_163 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011376 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_165 (Porphyromonadaceae) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011377 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_1 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011354 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_173 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011379 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_101 (Sutterella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011356 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_2 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011381 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_21 (Parasutterella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011382 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_108 (Phascolarctobacterium) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011360 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_235 (Phascolarctobacterium) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011384 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_11 (Parabacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011362 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_113 (Bacteroidales) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011363 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_26 (Parasutterella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011387 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_27 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011388 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_277 (Prevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011389 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_126 (Prevotella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011367 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_30 (Roseburia) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011391 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_137 (Catenibacterium) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011370 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_33 (Holdemanella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011393 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_15 (Parasutterella) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011373 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. OTU97_150 (Bacteroides) abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011374 Genome-wide genotyping array 8956 2020-01-07 31754094 Pisanu C 2019-11-21 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31754094 Evidence that genes involved in hedgehog signaling are associated with both bipolar disorder and high BMI. Bipolar disorder or body mass index 20,352 European ancestry bipolar disorder cases, 31,358 European ancestry controls, 322,154 European ancestry individuals with BMI data. NA Illumina [2013566] (imputed) 13 bipolar disorder, body mass index http://www.ebi.ac.uk/efo/EFO_0000289, http://www.ebi.ac.uk/efo/EFO_0004340 GCST009371 Genome-wide genotyping array, Targeted genotyping array 373864 2020-01-07 31754094 Pisanu C 2019-11-21 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31754094 Evidence that genes involved in hedgehog signaling are associated with both bipolar disorder and high BMI. Bipolar disorder or type 2 diabetes 20,352 European ancestry bipolar disorder cases, 26,676 European ancestry type 2 diabetes cases, 163,890 European ancestry controls NA NR [2013566] (imputed) 2 bipolar disorder, type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0000289, http://www.ebi.ac.uk/efo/EFO_0001360 GCST009372 Genome-wide genotyping array 210920 2020-04-17 31906708 Levey DF 2020-01-07 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/31906708 Reproducible Genetic Risk Loci for Anxiety: Results From ∼200,000 Participants in the Million Veteran Program. Anxiety 175,163 European ancestry individuals, 24,448 African American individuals NA Affymetrix [at least 723305] (imputed) 6 anxiety measurement http://www.ebi.ac.uk/efo/EFO_0009863 GCST009837 Genome-wide genotyping array 199611 2020-04-17 31906708 Levey DF 2020-01-07 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/31906708 Reproducible Genetic Risk Loci for Anxiety: Results From ∼200,000 Participants in the Million Veteran Program. Anxiety disorders 28,525 European ancestry cases, 5,664 African American cases, 163,731 European ancestry controls, 26,410 African American controls NA Affymetrix [at least 723305] (imputed) 2 anxiety disorder, panic disorder http://www.ebi.ac.uk/efo/EFO_0006788, http://www.ebi.ac.uk/efo/EFO_0004262 GCST009838 Genome-wide genotyping array 224330 2020-04-17 31903573 van Reij RRI 2020-01-01 Anaesthesia www.ncbi.nlm.nih.gov/pubmed/31903573 The association between genome-wide polymorphisms and chronic postoperative pain: a prospective observational study. Chronic postoperative pain 34 European ancestry cases, 269 European ancestry controls 11 European ancestry cases, 39 European ancestry controls Illumina [6293655] (imputed) 2 chronic post-operative pain measurement http://www.ebi.ac.uk/efo/EFO_0010640 GCST009839 Genome-wide genotyping array 303 2020-02-19 31910446 Oh SW 2020-01-07 PLoS One www.ncbi.nlm.nih.gov/pubmed/31910446 Genome-wide association study of metabolic syndrome in Korean populations. Metabolic syndrome 1,362 Korean ancestry cases, 6,061 Korean ancestry controls NA Affymetrix [at least 584061] (imputed) 1 metabolic syndrome http://www.ebi.ac.uk/efo/EFO_0000195 GCST009663 Genome-wide genotyping array 7423 2020-02-19 31910446 Oh SW 2020-01-07 PLoS One www.ncbi.nlm.nih.gov/pubmed/31910446 Genome-wide association study of metabolic syndrome in Korean populations. Hypertriglyceridemia 7,423 Korean ancestry cases and controls NA Affymetrix [at least 584061] (imputed) 18 Hypertriglyceridemia http://www.ebi.ac.uk/efo/EFO_0004211 GCST009662 Genome-wide genotyping array 7423 2020-02-19 31910446 Oh SW 2020-01-07 PLoS One www.ncbi.nlm.nih.gov/pubmed/31910446 Genome-wide association study of metabolic syndrome in Korean populations. Low HDL-cholesterol levels 7,423 Korean ancestry cases and controls NA Affymetrix [at least 584061] (imputed) 17 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST009661 Genome-wide genotyping array 7423 2020-02-19 31910446 Oh SW 2020-01-07 PLoS One www.ncbi.nlm.nih.gov/pubmed/31910446 Genome-wide association study of metabolic syndrome in Korean populations. High fasting blood glucose 7,423 Korean ancestry cases and controls NA Affymetrix [at least 584061] (imputed) 1 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST009660 Genome-wide genotyping array 7423 2020-02-19 31910446 Oh SW 2020-01-07 PLoS One www.ncbi.nlm.nih.gov/pubmed/31910446 Genome-wide association study of metabolic syndrome in Korean populations. Hypertension 7,423 Korean ancestry cases and controls NA Affymetrix [at least 584061] (imputed) 0 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST009659 Genome-wide genotyping array 7423 2020-02-19 31910446 Oh SW 2020-01-07 PLoS One www.ncbi.nlm.nih.gov/pubmed/31910446 Genome-wide association study of metabolic syndrome in Korean populations. Metabolic syndrome 502 Korean ancestry cases, 1,751 Korean ancestry controls NA Affymetrix [at least 584061] (imputed) 0 metabolic syndrome http://www.ebi.ac.uk/efo/EFO_0000195 GCST009658 Genome-wide genotyping array 2253 2020-02-19 31910446 Oh SW 2020-01-07 PLoS One www.ncbi.nlm.nih.gov/pubmed/31910446 Genome-wide association study of metabolic syndrome in Korean populations. Hypertriglyceridemia 2,253 Korean ancestry cases and controls NA Affymetrix [at least 584061] (imputed) 2 Hypertriglyceridemia http://www.ebi.ac.uk/efo/EFO_0004211 GCST009657 Genome-wide genotyping array 2253 2020-02-19 31910446 Oh SW 2020-01-07 PLoS One www.ncbi.nlm.nih.gov/pubmed/31910446 Genome-wide association study of metabolic syndrome in Korean populations. Low HDL-cholesterol levels 2,253 Korean ancestry cases and controls NA Affymetrix [at least 584061] (imputed) 4 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST009656 Genome-wide genotyping array 2253 2020-02-19 31910446 Oh SW 2020-01-07 PLoS One www.ncbi.nlm.nih.gov/pubmed/31910446 Genome-wide association study of metabolic syndrome in Korean populations. High fasting blood glucose 2,253 Korean ancestry cases and controls NA Affymetrix [at least 584061] (imputed) 0 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST009655 Genome-wide genotyping array 2253 2020-02-19 31910446 Oh SW 2020-01-07 PLoS One www.ncbi.nlm.nih.gov/pubmed/31910446 Genome-wide association study of metabolic syndrome in Korean populations. Hypertension 2,253 Korean ancestry cases and controls NA Affymetrix [at least 584061] (imputed) 0 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST009654 Genome-wide genotyping array 2253 2020-01-28 31670792 Ghorbani Mojarrad N 2019-10-31 JAMA Ophthalmol www.ncbi.nlm.nih.gov/pubmed/31670792 Association Between Polygenic Risk Score and Risk of Myopia. Refractive error (age-at-onset of spectacle wearing-inferred) 287,448 European ancestry individuals NA NR [~ 1100000] 0 refractive error measurement http://www.ebi.ac.uk/efo/EFO_0007814 GCST009520 Genome-wide genotyping array 287448 2020-01-28 31670792 Ghorbani Mojarrad N 2019-10-31 JAMA Ophthalmol www.ncbi.nlm.nih.gov/pubmed/31670792 Association Between Polygenic Risk Score and Risk of Myopia. Refractive error (autorefraction measured) 95,619 European ancestry individuals NA NR [~ 1100000] 0 refractive error measurement http://www.ebi.ac.uk/efo/EFO_0007814 GCST009521 Genome-wide genotyping array 95619 2019-03-18 30643258 Karlsson Linner R 2019-01-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30643258 Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. Adventurousness 557,923 European ancestry individuals NA Illumina [9339358] (imputed) 167 risk-taking behaviour http://www.ebi.ac.uk/efo/EFO_0008579 GCST007324 Genome-wide genotyping array 557923 2019-03-18 30643258 Karlsson Linner R 2019-01-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30643258 Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. Automobile speeding propensity 404,291 European ancestry individuals NA Affymetrix [11514463] (imputed) 42 risk-taking behaviour http://www.ebi.ac.uk/efo/EFO_0008579 GCST007329 Genome-wide genotyping array 404291 2019-03-18 30643258 Karlsson Linner R 2019-01-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30643258 Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. Alcohol consumption (drinks per week) 414,343 European ancestry individuals NA Affymetrix [11514936] (imputed) 85 alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0007878 GCST007328 Genome-wide genotyping array 414343 2019-03-18 30643258 Karlsson Linner R 2019-01-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30643258 Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. Smoking status (ever vs never smokers) 518,633 European ancestry individuals NA Affymetrix [11514654] (imputed) 223 smoking behavior http://www.ebi.ac.uk/efo/EFO_0004318 GCST007327 Genome-wide genotyping array 518633 2019-03-18 30643258 Karlsson Linner R 2019-01-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30643258 Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. Number of sexual partners 370,711 European ancestry individuals NA Affymetrix [11515109] (imputed) 118 risky sexual behaviour measurement http://www.ebi.ac.uk/efo/EFO_0007877 GCST007326 Genome-wide genotyping array 370711 2019-03-18 30643258 Karlsson Linner R 2019-01-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30643258 Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. General risk tolerance (MTAG) 975,353 European ancestry individuals NA Affymetrix, Illumina [5869552] (imputed) 312 risk-taking behaviour http://www.ebi.ac.uk/efo/EFO_0008579 GCST007325 Genome-wide genotyping array 975353 2019-03-18 30643258 Karlsson Linner R 2019-01-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30643258 Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. Risk-taking tendency (4-domain principal component model) 315,894 European ancestry individuals NA Affymetrix [~ 11515000] (imputed) 106 risk-taking behaviour http://www.ebi.ac.uk/efo/EFO_0008579 GCST007323 Genome-wide genotyping array 315894 2019-03-18 30643258 Karlsson Linner R 2019-01-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30643258 Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. General risk tolerance 939,908 European ancestry individuals 35,445 European ancestry individuals Affymetrix, Illumina [9284738] (imputed) 0 risk-taking behaviour http://www.ebi.ac.uk/efo/EFO_0008579 GCST007322 Genome-wide genotyping array 939908 2020-07-09 32047268 von Berg J 2020-02-11 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32047268 Alternate approach to stroke phenotyping identifies a genetic risk locus for small vessel stroke. Cardioembolic stroke (CCSp classification) 3,608 European and African ancestry cases, 28,026 European and unknown ancestry controls NA Illumina [~ 10156805] (imputed) 3 cardioembolic stroke http://www.ebi.ac.uk/efo/EFO_1001976 GCST010166 Genome-wide genotyping array 31634 2020-07-09 32047268 von Berg J 2020-02-11 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32047268 Alternate approach to stroke phenotyping identifies a genetic risk locus for small vessel stroke. Cardioembolic stroke (TOAST classification) 3,333 European and African ancestry cases, 28,026 European and unknown ancestry controls NA Illumina [~ 10156805] (imputed) 2 cardioembolic stroke http://www.ebi.ac.uk/efo/EFO_1001976 GCST010165 Genome-wide genotyping array 31359 2020-07-09 32047268 von Berg J 2020-02-11 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32047268 Alternate approach to stroke phenotyping identifies a genetic risk locus for small vessel stroke. Cardioembolic stroke (CCS and TOAST classification) 2,219 European and African ancestry cases, 28,026 European and unknown ancestry controls NA Illumina [~ 10156805] (imputed) 3 cardioembolic stroke http://www.ebi.ac.uk/efo/EFO_1001976 GCST010164 Genome-wide genotyping array 30245 2020-07-09 32047268 von Berg J 2020-02-11 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32047268 Alternate approach to stroke phenotyping identifies a genetic risk locus for small vessel stroke. Cardioembolic stroke (CCS or TOAST classification) 4,502 European and African ancestry cases, 28,026 European and unknown ancestry controls NA Illumina [~ 10156805] (imputed) 2 cardioembolic stroke http://www.ebi.ac.uk/efo/EFO_1001976 GCST010163 Genome-wide genotyping array 32528 2020-07-09 32047268 von Berg J 2020-02-11 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32047268 Alternate approach to stroke phenotyping identifies a genetic risk locus for small vessel stroke. Large artery stroke (CCSc classification) 1,565 European and African ancestry cases, 28,026 European and unknown ancestry controls NA Illumina [~ 10156805] (imputed) 0 large artery stroke http://www.ebi.ac.uk/efo/EFO_0005524 GCST010162 Genome-wide genotyping array 29591 2020-07-09 32047268 von Berg J 2020-02-11 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32047268 Alternate approach to stroke phenotyping identifies a genetic risk locus for small vessel stroke. Large artery stroke (CCSp classification)j 2,449 European and African ancestry cases, 28,026 European and unknown ancestry controls NA Illumina [~ 10156805] (imputed) 2 large artery stroke http://www.ebi.ac.uk/efo/EFO_0005524 GCST010161 Genome-wide genotyping array 30475 2020-07-09 32047268 von Berg J 2020-02-11 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32047268 Alternate approach to stroke phenotyping identifies a genetic risk locus for small vessel stroke. Large artery stroke (TOAST classification) 2,318 European and African ancestry cases, 28,026 European and unknown ancestry controls NA Illumina [~ 10156805] (imputed) 2 large artery stroke http://www.ebi.ac.uk/efo/EFO_0005524 GCST010160 Genome-wide genotyping array 30344 2020-07-09 32047268 von Berg J 2020-02-11 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32047268 Alternate approach to stroke phenotyping identifies a genetic risk locus for small vessel stroke. Large artery stroke (CCS and TOAST classification) 1,328 European and African ancestry cases, 28,026 European and unknown ancestry controls NA Illumina [~ 10156805] (imputed) 2 large artery stroke http://www.ebi.ac.uk/efo/EFO_0005524 GCST010159 Genome-wide genotyping array 29354 2020-07-09 32047268 von Berg J 2020-02-11 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32047268 Alternate approach to stroke phenotyping identifies a genetic risk locus for small vessel stroke. Large artery stroke (CCS or TOAST classification) 3,495 European and African ancestry cases, 28,026 European and unknown ancestry controls NA Illumina [~ 10156805] (imputed) 2 large artery stroke http://www.ebi.ac.uk/efo/EFO_0005524 GCST010158 Genome-wide genotyping array 31521 2020-07-09 32047268 von Berg J 2020-02-11 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32047268 Alternate approach to stroke phenotyping identifies a genetic risk locus for small vessel stroke. Small vessel stroke (CCSc classification) 2,262 European and African ancestry cases, 28,026 European and unknown ancestry controls NA Illumina [~ 10156805] (imputed) 0 small vessel stroke http://www.ebi.ac.uk/efo/EFO_1001504 GCST010157 Genome-wide genotyping array 30288 2020-07-09 32047268 von Berg J 2020-02-11 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32047268 Alternate approach to stroke phenotyping identifies a genetic risk locus for small vessel stroke. Small vessel stroke (CCSp classification) 2,419 European and African ancestry cases, 28,026 European and unknown ancestry controls NA Illumina [~ 10156805] (imputed) 2 small vessel stroke http://www.ebi.ac.uk/efo/EFO_1001504 GCST010156 Genome-wide genotyping array 30445 2020-07-09 32047268 von Berg J 2020-02-11 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32047268 Alternate approach to stroke phenotyping identifies a genetic risk locus for small vessel stroke. Small vessel stroke (TOAST classification) 2,631 European and African ancestry cases, 28,026 European and unknown ancestry controls NA Illumina [~ 10156805] (imputed) 0 small vessel stroke http://www.ebi.ac.uk/efo/EFO_1001504 GCST010155 Genome-wide genotyping array 30657 2020-07-09 32047268 von Berg J 2020-02-11 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32047268 Alternate approach to stroke phenotyping identifies a genetic risk locus for small vessel stroke. Small vessel stroke (CCS and TOAST classification) 1,548 European and African ancestry cases, 28,026 European and unknown ancestry controls NA Illumina [~ 10156805] (imputed) 1 small vessel stroke http://www.ebi.ac.uk/efo/EFO_1001504 GCST010154 Genome-wide genotyping array 29574 2020-07-09 32047268 von Berg J 2020-02-11 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32047268 Alternate approach to stroke phenotyping identifies a genetic risk locus for small vessel stroke. Small vessel stroke (CCS or TOAST classification) 3,480 European and African ancestry cases, 28,026 European and unknown ancestry controls NA Illumina [~ 10156805] (imputed) 1 small vessel stroke http://www.ebi.ac.uk/efo/EFO_1001504 GCST010153 Genome-wide genotyping array 31506 2020-07-09 32047268 von Berg J 2020-02-11 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32047268 Alternate approach to stroke phenotyping identifies a genetic risk locus for small vessel stroke. Cardioembolic stroke (CCSc classification) 3,000 European and African ancestry cases, 28,026 European and unknown ancestry controls NA Illumina [~ 10156805] (imputed) 4 cardioembolic stroke http://www.ebi.ac.uk/efo/EFO_1001976 GCST010167 Genome-wide genotyping array 31026 2020-05-28 32072174 Okamoto D 2020-02-19 Inflamm Bowel Dis www.ncbi.nlm.nih.gov/pubmed/32072174 Genetic Analysis of Ulcerative Colitis in Japanese Individuals Using Population-specific SNP Array. Ulcerative colitis 601 Japanese ancestry cases, 1,962 Japanese ancestry controls 1,075 Japanese ancestry cases, 419 Japanese ancestry controls NR [4760823] (imputed) 3 ulcerative colitis http://www.ebi.ac.uk/efo/EFO_0000729 GCST010001 Genome-wide genotyping array 2563 2020-07-08 32062564 Guo Y 2020-02-06 Neuroimage Clin www.ncbi.nlm.nih.gov/pubmed/32062564 Genome-wide association study of white matter hyperintensity volume in elderly persons without dementia. White matter hyperintensity volume 350 European ancestry elderly individuals NA Illumina [695203] (imputed) 3 white matter hyperintensity measurement http://www.ebi.ac.uk/efo/EFO_0005665 GCST010147 Genome-wide genotyping array 350 2020-07-21 32205469 Akcimen F 2020-03-23 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/32205469 Genome-wide association study identifies genetic factors that modify age at onset in Machado-Joseph disease. Machado-Joseph disease (age at onset) 700 cases NA Illumina [6716580] (imputed) 8 Machado-Joseph disease, age at onset http://purl.obolibrary.org/obo/MONDO_0007182, http://www.ebi.ac.uk/efo/EFO_0004847 GCST010248 Genome-wide genotyping array 700 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Triglyceride levels up to 23,508 African ancestry individuals, 4,649 Asian ancestry individuals, up to 77,047 European ancestry individuals, 6,705 Hispanic individuals NA Affymetrix, Illumina, Perlegen [NR] (imputed) 48 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST008702 Genome-wide genotyping array 111909 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. HDL cholesterol levels x smoking (current vs non smokers) interaction (1df test) 5,120 African ancestry current smoker individuals, 2,394 Asian ancestry current smoker individuals, 15,129 European ancestry current smoker individuals, 747 Hispanic current smoker individuals, 18,641 African ancestry non smoker individuals, 10,777 Asian ancestry non smoker individuals, 75,138 European ancestry non smoker individuals, 5,873 Hispanic non smoker individuals 1,825 African ancestry current smoker individuals, 16,241 Asian ancestry current smoker individuals, 32,416 European ancestry current smoker individuals, 3,570 Hispanic current smoker individuals, 5,392 African ancestry non smoker individuals, 65,276 Asian ancestry non smoker individuals, 114,795 European ancestry non smoker individuals, 13,952 Hispanic non smoker individuals Affymetrix, Illumina, Perlegen [NR] (imputed) 2 smoking status measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0004612 GCST008677 Genome-wide genotyping array 133819 2020-01-07 31755389 Li J 2019-11-21 Curr Alzheimer Res www.ncbi.nlm.nih.gov/pubmed/31755389 Genome-wide Network-assisted Association and Enrichment Study of Amyloid Imaging Phenotype in Alzheimer's Disease. Cerebral cortex AV-45 amyloid PET measurement 155 cognitively normal individuals, 72 significant memory concern individuals, 278 with early mild cognitive impairment individuals, 144 late mild cognitive impairment individuals, 125 Alzheimer's disease cases. NA Illumina [563980] 1 cerebral amyloid deposition measurement http://www.ebi.ac.uk/efo/EFO_0007707 GCST009376 Genome-wide genotyping array 774 2020-09-16 32574161 Dapas M 2020-06-23 PLoS Med www.ncbi.nlm.nih.gov/pubmed/32574161 Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis. Polycystic ovary syndrome (reproductive subtype) 123 European ancestry cases, 2,964 European ancestry controls 84 European ancestry cases, 1,134 European ancestry controls Illumina [NR] (imputed) 5 polycystic ovary syndrome http://www.ebi.ac.uk/efo/EFO_0000660 GCST010570 Genome-wide genotyping array 3087 2020-09-16 32574161 Dapas M 2020-06-23 PLoS Med www.ncbi.nlm.nih.gov/pubmed/32574161 Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis. Polycystic ovary syndrome (metabolic subtype) 201 European ancestry cases, 2,964 European ancestry controls 128 European ancestry cases, 1,134 European ancestry controls Illumina [NR] (imputed) 1 polycystic ovary syndrome http://www.ebi.ac.uk/efo/EFO_0000660 GCST010569 Genome-wide genotyping array 3165 2020-09-16 32574161 Dapas M 2020-06-23 PLoS Med www.ncbi.nlm.nih.gov/pubmed/32574161 Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis. Polycystic ovary syndrome (indeterminate subtype) 231 European ancestry cases, 2,964 European ancestry controls 126 European ancestry cases, 1,134 European ancestry controls Illumina [NR] (imputed) 1 polycystic ovary syndrome http://www.ebi.ac.uk/efo/EFO_0000660 GCST010568 Genome-wide genotyping array 3195 2020-09-24 32605384 Choquet H 2020-06-30 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/32605384 Meta-analysis of 26,638 Individuals Identifies Two Genetic Loci Associated with Left Ventricular Ejection Fraction. Left ventricular ejection fraction 18,670 European ancestry individuals, 1,207 East Asian ancestry individuals, 1,514 Hispanic/Latino individuals, 764 African American individuals NA Affymetrix [10432573] (imputed) 1 left ventricular ejection fraction measurement http://www.ebi.ac.uk/efo/EFO_0008373 GCST90006790 Genome-wide genotyping array 22155 2020-09-24 32605384 Choquet H 2020-06-30 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/32605384 Meta-analysis of 26,638 Individuals Identifies Two Genetic Loci Associated with Left Ventricular Ejection Fraction. Left ventricular ejection fraction 4,483 European ancestry individuals NA Affymetrix [12703989] (imputed) 1 left ventricular ejection fraction measurement http://www.ebi.ac.uk/efo/EFO_0008373 GCST90006791 Genome-wide genotyping array 4483 2020-09-24 32605384 Choquet H 2020-06-30 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/32605384 Meta-analysis of 26,638 Individuals Identifies Two Genetic Loci Associated with Left Ventricular Ejection Fraction. Left ventricular ejection fraction 23,153 European ancestry individuals, 1,207 East Asian ancestry individuals, 1,514 Hispanic/Latino individuals, 764 African American individuals NA Affymetrix [10432573] (imputed) 2 left ventricular ejection fraction measurement http://www.ebi.ac.uk/efo/EFO_0008373 GCST010617 Genome-wide genotyping array 26638 2020-02-05 31919418 Shah S 2020-01-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31919418 Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure. Heart failure 47,309 European ancestry cases, 930,014 European ancestry controls NA Affymetrix, Illumina [8246881] (imputed) 12 heart failure http://www.ebi.ac.uk/efo/EFO_0003144 GCST009541 Genome-wide genotyping array 977323 2020-03-11 29381148 Gong J 2017-12-21 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/29381148 Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI. Body mass index 35,606 African American individuals, 26,048 Hispanic/Latino individuals, 22,466 Asian or Native Hawaiian ancestry individuals, 17,859 European ancestry individuals, 535 Native American individuals NA Illumina [at least 200000] 27 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST009764 Targeted genotyping array [Metabochip] 102514 2020-07-09 32149159 Chen YM 2020-02-14 J Immunol Res www.ncbi.nlm.nih.gov/pubmed/32149159 Genetic Association and Expression Correlation between Colony-Stimulating Factor 1 Gene Encoding M-CSF and Adult-Onset Still's Disease. Adult onset Still's disease 70 Han Chinese ancestry cases, 688 Han Chinese ancestry controls 36 Han Chinese ancestry cases, 200 Han Chinese ancestry controls Affymetrix [645983] 1 adult-onset Still's disease http://www.ebi.ac.uk/efo/EFO_0007135 GCST010175 Genome-wide genotyping array 758 2019-11-26 31689377 Wootton RE 2019-11-06 Psychol Med www.ncbi.nlm.nih.gov/pubmed/31689377 Evidence for causal effects of lifetime smoking on risk for depression and schizophrenia: a Mendelian randomisation study. Lifetime smoking index 462,690 European ancestry individuals NA Affymetrix [up to 90000000] (imputed) 126 smoking behaviour measurement http://www.ebi.ac.uk/efo/EFO_0005671 GCST009096 Genome-wide genotyping array 462690 2020-02-18 31754133 Singh S 2019-11-21 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31754133 Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response. Systolic blood pressure response to thiazide and thiazide-like diuretics in hypertension 290 African American individuals, 397 European ancestry individuals NA Illumina [NR] (imputed) 2 response to diuretic, systolic blood pressure change measurement http://purl.obolibrary.org/obo/GO_0036270, http://www.ebi.ac.uk/efo/EFO_0006944 GCST009645 Genome-wide genotyping array 687 2020-02-18 31754133 Singh S 2019-11-21 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31754133 Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response. Diastolic blood pressure response to thiazide and thiazide-like diuretics in hypertension 290 African American individuals, 397 European ancestry individuals NA Illumina [NR] (imputed) 4 response to diuretic, diastolic blood pressure change measurement http://purl.obolibrary.org/obo/GO_0036270, http://www.ebi.ac.uk/efo/EFO_0006945 GCST009646 Genome-wide genotyping array 687 2020-02-18 31754133 Singh S 2019-11-21 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31754133 Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response. Systolic blood pressure response to chlorthalidone in hypertension 142 African American individuals, 175 European ancestry individuals NA Illumina [NR] (imputed) 59 response to diuretic, systolic blood pressure change measurement http://purl.obolibrary.org/obo/GO_0036270, http://www.ebi.ac.uk/efo/EFO_0006944 GCST009644 Genome-wide genotyping array 317 2020-02-18 31754133 Singh S 2019-11-21 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31754133 Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response. Diastolic blood pressure response to chlorthalidone in hypertension 142 African American individuals, 175 European ancestry individuals NA Illumina [NR] (imputed) 88 response to diuretic, diastolic blood pressure change measurement http://purl.obolibrary.org/obo/GO_0036270, http://www.ebi.ac.uk/efo/EFO_0006945 GCST009643 Genome-wide genotyping array 317 2020-04-29 31801372 Strawbridge RJ 2019-12-05 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/31801372 Carotid Intima-Media Thickness: Novel Loci, Sex-Specific Effects, and Genetic Correlations With Obesity and Glucometabolic Traits in UKB. Carotid intima media thickness (mean) 10,708 British ancestry men, 11,471 British ancestry women NA NR [NR] (imputed) 12 carotid artery intima media thickness http://www.ebi.ac.uk/efo/EFO_0007117 GCST009921 Genome-wide genotyping array 22179 2020-03-06 31801372 Strawbridge RJ 2019-12-05 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/31801372 Carotid Intima-Media Thickness: Novel Loci, Sex-Specific Effects, and Genetic Correlations With Obesity and Glucometabolic Traits in UKB. Carotid intima media thickness (maximum) 22,179 British ancestry individuals NA NR [NR] (imputed) 3 carotid artery intima media thickness http://www.ebi.ac.uk/efo/EFO_0007117 GCST009738 Genome-wide genotyping array 22179 2020-03-06 31801372 Strawbridge RJ 2019-12-05 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/31801372 Carotid Intima-Media Thickness: Novel Loci, Sex-Specific Effects, and Genetic Correlations With Obesity and Glucometabolic Traits in UKB. Carotid intima media thickness (mean-maximum) 22,179 British ancestry individuals NA NR [NR] (imputed) 12 carotid artery intima media thickness http://www.ebi.ac.uk/efo/EFO_0007117 GCST009739 Genome-wide genotyping array 22179 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. HDL cholesterol levels x smoking (current vs non smokers) interaction (2df test) 5,120 African ancestry current smoker individuals, 2,394 Asian ancestry current smoker individuals, 15,129 European ancestry current smoker individuals, 747 Hispanic current smoker individuals, 18,641 African ancestry non smoker individuals, 10,777 Asian ancestry non smoker individuals, 75,138 European ancestry non smoker individuals, 5,873 Hispanic non smoker individuals 1,825 African ancestry current smoker individuals, 16,241 Asian ancestry current smoker individuals, 32,416 European ancestry current smoker individuals, 3,570 Hispanic current smoker individuals, 5,392 African ancestry non smoker individuals, 65,276 Asian ancestry non smoker individuals, 114,795 European ancestry non smoker individuals, 13,952 Hispanic non smoker individuals Affymetrix, Illumina, Perlegen [NR] (imputed) 8 smoking status measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0004612 GCST008678 Genome-wide genotyping array 133819 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. HDL cholesterol levels in current smokers 5,120 African ancestry individuals, 2,394 Asian ancestry individuals, 15,129 European ancestry individuals, 747 Hispanic individuals NA Affymetrix, Illumina, Perlegen [NR] (imputed) 0 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST008679 Genome-wide genotyping array 23390 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. HDL cholesterol levels in non smokers 18,641 African ancestry individuals, 10,777 Asian ancestry individuals, 75,138 European ancestry individuals, 5,873 Hispanic individuals NA Affymetrix, Illumina, Perlegen [NR] (imputed) 2 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST008680 Genome-wide genotyping array 110429 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. HDL cholesterol levels x smoking (ever vs never smokers) interaction (1df test) 11,893 African ancestry ever smoker individuals, 4,025 Asian ancestry ever smoker individuals, 49,475 European ancestry ever smoker individuals, 2,544 Hispanic ever smoker individuals, 11,866 African ancestry never smoker individuals, 9,146 Asian ancestry never smoker individuals, 40,797 European ancestry never smoker individuals, 4,076 Hispanic never smoker individuals 2,827 African ancestry ever smoker individuals, 37,952 Asian ancestry ever smoker individuals, 82,808 European ancestry ever smoker individuals, 7,091 Hispanic ever smoker individuals, 2,785 African ancestry never smoker individuals, 43,565 Asian ancestry never smoker individuals, 64,252 European ancestry never smoker individuals, 10,431 Hispanic never smoker individuals Affymetrix, Illumina, Perlegen [NR] (imputed) 2 smoking status measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0004612 GCST008681 Genome-wide genotyping array 133822 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. HDL cholesterol levels x smoking (ever vs never smokers) interaction (2df test) 11,893 African ancestry ever smoker individuals, 4,025 Asian ancestry ever smoker individuals, 49,475 European ancestry ever smoker individuals, 2,544 Hispanic ever smoker individuals, 11,866 African ancestry never smoker individuals, 9,146 Asian ancestry never smoker individuals, 40,797 European ancestry never smoker individuals, 4,076 Hispanic never smoker individuals 2,827 African ancestry ever smoker individuals, 37,952 Asian ancestry ever smoker individuals, 82,808 European ancestry ever smoker individuals, 7,091 Hispanic ever smoker individuals, 2,785 African ancestry never smoker individuals, 43,565 Asian ancestry never smoker individuals, 64,252 European ancestry never smoker individuals, 10,431 Hispanic never smoker individuals Affymetrix, Illumina, Perlegen [NR] (imputed) 5 smoking status measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0004612 GCST008682 Genome-wide genotyping array 133822 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. HDL cholesterol levels in ever smokers 11,893 African ancestry individuals, 4,025 Asian ancestry individuals, 49,475 European ancestry individuals, 2,544 Hispanic individuals NA Affymetrix, Illumina, Perlegen [NR] (imputed) 0 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST008683 Genome-wide genotyping array 67937 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. HDL cholesterol levels in never smokers 11,866 African ancestry individuals, 9,146 Asian ancestry individuals, 40,797 European ancestry individuals, 4,076 Hispanic individuals NA Affymetrix, Illumina, Perlegen [NR] (imputed) 1 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST008684 Genome-wide genotyping array 65885 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. HDL cholesterol levels up to 23,761 African ancestry individuals, 13,171 Asian ancestry individuals, up to 90,272 European ancestry individuals, 6,620 Hispanic individuals NA Affymetrix, Illumina, Perlegen [NR] (imputed) 87 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST008685 Genome-wide genotyping array 133824 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. LDL cholesterol levels x smoking (current vs non smokers) interaction (1df test) 4,973 African ancestry current smoker individuals, 2,375 Asian ancestry current smoker individuals, 13,799 European ancestry current smoker individuals, 755 Hispanic current smoker individuals, 18,384 African ancestry non smoker individuals, 10,742 Asian ancestry non smoker individuals, 68,719 European ancestry non smoker individuals, 5,894 Hispanic non smoker individuals 1,357 African ancestry current smoker individuals, 8,901 Asian ancestry current smoker individuals, 25,008 European ancestry current smoker individuals, 3,441 Hispanic current smoker individuals, 3,967 African ancestry non smoker individuals, 39,448 Asian ancestry non smoker individuals, 92,432 European ancestry non smoker individuals, 13,555 Hispanic non smoker individuals Affymetrix, Illumina, Perlegen [NR] (imputed) 3 smoking status measurement, low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0004611 GCST008686 Genome-wide genotyping array 125641 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. LDL cholesterol levels x smoking (current vs non smokers) interaction (2df test) 4,973 African ancestry current smoker individuals, 2,375 Asian ancestry current smoker individuals, 13,799 European ancestry current smoker individuals, 755 Hispanic current smoker individuals, 18,384 African ancestry non smoker individuals, 10,742 Asian ancestry non smoker individuals, 68,719 European ancestry non smoker individuals, 5,894 Hispanic non smoker individuals 1,357 African ancestry current smoker individuals, 8,901 Asian ancestry current smoker individuals, 25,008 European ancestry current smoker individuals, 3,441 Hispanic current smoker individuals, 3,967 African ancestry non smoker individuals, 39,448 Asian ancestry non smoker individuals, 92,432 European ancestry non smoker individuals, 13,555 Hispanic non smoker individuals Affymetrix, Illumina, Perlegen [NR] (imputed) 5 smoking status measurement, low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0004611 GCST008687 Genome-wide genotyping array 125641 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. LDL cholesterol levels in current smokers 4,973 African ancestry individuals, 2,375 Asian ancestry individuals, 13,799 European ancestry individuals, 755 Hispanic individuals NA Affymetrix, Illumina, Perlegen [NR] (imputed) 2 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST008688 Genome-wide genotyping array 21902 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. LDL cholesterol levels in non smokers 18,384 African ancestry individuals, 10,742 Asian ancestry individuals, 68,719 European ancestry individuals, 5,894 Hispanic individuals NA Affymetrix, Illumina, Perlegen [NR] (imputed) 0 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST008689 Genome-wide genotyping array 103739 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. LDL cholesterol levels x smoking (ever vs never smokers) interaction (1df test) 11,649 African ancestry ever smoker individuals, 3,999 Asian ancestry ever smoker individuals, 45,506 European ancestry ever smoker individuals, 2,554 Hispanic ever smoker individuals, 11,700 African ancestry never smoker individuals, 9,118 Asian ancestry never smoker individuals, 37,016 European ancestry never smoker individuals, 4,095 Hispanic never smoker individuals 1,693 African ancestry ever smoker individuals, 20,368 Asian ancestry ever smoker individuals, 65,806 European ancestry ever smoker individuals, 6,857 Hispanic ever smoker individuals, 2,025 African ancestry never smoker individuals, 27,981 Asian ancestry never smoker individuals, 51,361 European ancestry never smoker individuals, 10,139 Hispanic never smoker individuals Affymetrix, Illumina, Perlegen [NR] (imputed) 2 smoking status measurement, low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0004611 GCST008690 Genome-wide genotyping array 125637 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. LDL cholesterol levels x smoking (ever vs never smokers) interaction (2df test) 11,649 African ancestry ever smoker individuals, 3,999 Asian ancestry ever smoker individuals, 45,506 European ancestry ever smoker individuals, 2,554 Hispanic ever smoker individuals, 11,700 African ancestry never smoker individuals, 9,118 Asian ancestry never smoker individuals, 37,016 European ancestry never smoker individuals, 4,095 Hispanic never smoker individuals 1,693 African ancestry ever smoker individuals, 20,368 Asian ancestry ever smoker individuals, 65,806 European ancestry ever smoker individuals, 6,857 Hispanic ever smoker individuals, 2,025 African ancestry never smoker individuals, 27,981 Asian ancestry never smoker individuals, 51,361 European ancestry never smoker individuals, 10,139 Hispanic never smoker individuals Affymetrix, Illumina, Perlegen [NR] (imputed) 4 smoking status measurement, low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0004611 GCST008691 Genome-wide genotyping array 125637 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. LDL cholesterol levels in ever smokers 11,649 African ancestry individuals, 3,999 Asian ancestry individuals, 45,506 European ancestry individuals, 2,554 Hispanic individuals NA Affymetrix, Illumina, Perlegen [NR] (imputed) 1 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST008692 Genome-wide genotyping array 63708 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. LDL cholesterol levels in never smokers 11,700 African ancestry individuals, 9,118 Asian ancestry individuals, 37,016 European ancestry individuals, 4,095 Hispanic individuals NA Affymetrix, Illumina, Perlegen [NR] (imputed) 1 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST008693 Genome-wide genotyping array 61929 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. LDL cholesterol levels up to 23,353 African ancestry individuals, 13,171 Asian ancestry individuals, up to 82,522 European ancestry individuals, 6,646 Hispanic individuals NA Affymetrix, Illumina, Perlegen [NR] (imputed) 62 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST008676 Genome-wide genotyping array 125692 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Triglyceride levels x smoking (current vs non smokers) interaction (1df test) 5,022 African ancestry current smoker individuals, 808 Asian ancestry current smoker individuals, 13,303 European ancestry current smoker individuals, 764 Hispanic current smoker individuals, 18,489 African ancestry non smoker individuals, 3,841 Asian ancestry non smoker individuals, 63,740 European ancestry non smoker individuals, 5,941 Hispanic non smoker individuals 1,367 African ancestry current smoker individuals, 22,744 Asian ancestry current smoker individuals, 22,268 European ancestry current smoker individuals, 2,899 Hispanic current smoker individuals, 3,989 African ancestry non smoker individuals, 89,177 Asian ancestry non smoker individuals, 86,885 European ancestry non smoker individuals, 11,811 Hispanic non smoker individuals Affymetrix, Illumina, Perlegen [NR] (imputed) 2 smoking status measurement, triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0004530 GCST008694 Genome-wide genotyping array 111908 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Triglyceride levels x smoking (current vs non smokers) interaction (2df test) 5,022 African ancestry current smoker individuals, 808 Asian ancestry current smoker individuals, 13,303 European ancestry current smoker individuals, 764 Hispanic current smoker individuals, 18,489 African ancestry non smoker individuals, 3,841 Asian ancestry non smoker individuals, 63,740 European ancestry non smoker individuals, 5,941 Hispanic non smoker individuals 1,367 African ancestry current smoker individuals, 22,744 Asian ancestry current smoker individuals, 22,268 European ancestry current smoker individuals, 2,899 Hispanic current smoker individuals, 3,989 African ancestry non smoker individuals, 89,177 Asian ancestry non smoker individuals, 86,885 European ancestry non smoker individuals, 11,811 Hispanic non smoker individuals Affymetrix, Illumina, Perlegen [NR] (imputed) 6 smoking status measurement, triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0004530 GCST008695 Genome-wide genotyping array 111908 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Triglyceride levels in current smokers 5,022 African ancestry individuals, 808 Asian ancestry individuals, 13,303 European ancestry individuals, 764 Hispanic individuals NA Affymetrix, Illumina, Perlegen [NR] (imputed) 0 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST008696 Genome-wide genotyping array 19897 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Triglyceride levels in non smokers 18,489 African ancestry individuals, 3,841 Asian ancestry individuals, 63,740 European ancestry individuals, 5,941 Hispanic individuals NA Affymetrix, Illumina, Perlegen [NR] (imputed) 2 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST008697 Genome-wide genotyping array 92011 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Triglyceride levels x smoking (ever vs never smokers) interaction (2df test) 11,735 African ancestry ever smoker individuals, 1,172 Asian ancestry ever smoker individuals, 42,899 European ancestry ever smoker individuals, 2,582 Hispanic ever smoker individuals, 11,777 African ancestry never smoker individuals, 3,477 Asian ancestry never smoker individuals, 34,148 European ancestry never smoker individuals, 4,123 Hispanic never smoker individuals 1,710 African ancestry ever smoker individuals, 54,217 Asian ancestry ever smoker individuals, 11,550 European ancestry ever smoker individuals, 5,915 Hispanic ever smoker individuals, 2,040 African ancestry never smoker individuals, 57,704 Asian ancestry never smoker individuals, 47,916 European ancestry never smoker individuals, 8,795 Hispanic never smoker individuals Affymetrix, Illumina, Perlegen [NR] (imputed) 4 smoking status measurement, triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0004530 GCST008698 Genome-wide genotyping array 111913 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Triglyceride levels x smoking (ever vs never smokers) interaction (1df test) 11,735 African ancestry ever smoker individuals, 1,172 Asian ancestry ever smoker individuals, 42,899 European ancestry ever smoker individuals, 2,582 Hispanic ever smoker individuals, 11,777 African ancestry never smoker individuals, 3,477 Asian ancestry never smoker individuals, 34,148 European ancestry never smoker individuals, 4,123 Hispanic never smoker individuals 1,710 African ancestry ever smoker individuals, 54,217 Asian ancestry ever smoker individuals, 11,550 European ancestry ever smoker individuals, 5,915 Hispanic ever smoker individuals, 2,040 African ancestry never smoker individuals, 57,704 Asian ancestry never smoker individuals, 60,675 European ancestry never smoker individuals, 8,795 Hispanic never smoker individuals Affymetrix, Illumina, Perlegen [NR] (imputed) 2 smoking status measurement, triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0004530 GCST008699 Genome-wide genotyping array 111913 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Triglyceride levels in ever smokers 11,735 African ancestry individuals, 1,172 Asian ancestry individuals, 42,899 European ancestry individuals, 2,582 Hispanic individuals NA Affymetrix, Illumina, Perlegen [NR] (imputed) 1 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST008700 Genome-wide genotyping array 58388 2019-09-19 30926973 Bentley AR 2019-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30926973 Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Triglyceride levels in never smokers 11,777 African ancestry individuals, 3,477 Asian ancestry individuals, 34,148 European ancestry individuals, 4,123 Hispanic individuals NA Affymetrix, Illumina, Perlegen [NR] (imputed) 0 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST008701 Genome-wide genotyping array 53525 2020-06-23 32390946 Liu L 2020-04-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/32390946 Twelve New Genomic Loci Associated With Bone Mineral Density. Heel bone mineral density (MTAG) 426,824 individuals NA NR [7369691] (imputed) 12 heel bone mineral density http://www.ebi.ac.uk/efo/EFO_0009270 GCST010091 Genome-wide genotyping array 426824 2020-06-23 32390946 Liu L 2020-04-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/32390946 Twelve New Genomic Loci Associated With Bone Mineral Density. Total body bone mineral density (MTAG) 66,628 individuals NA Affymetrix, Illumina [7369691] (imputed) 11 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST010092 Genome-wide genotyping array 66628 2021-05-19 32407400 Tekola-Ayele F 2020-05-14 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/32407400 Trans-ethnic meta-analysis of genome-wide association studies identifies maternal ITPR1 as a novel locus influencing fetal growth during sensitive periods in pregnancy. fetal weight (maternal genotype effect) 580 European ancestry individuals, 556 African American individuals, 508 Hispanic individuals, 205 East Asian individuals 55 European ancestry individuals, 57 African American individuals, 72 Hispanic individuals Illumina [NR] (imputed) 0 fetal weight, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0011045, http://www.ebi.ac.uk/efo/EFO_0005939 GCST011698 Genome-wide genotyping array 1849 2021-04-27 32929176 Feng GJ 2020-09-14 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32929176 Identification of pleiotropic loci underlying hip bone mineral density and trunk lean mass. Bone mineral density or trunk lean mass (pleiotropy) 8,508 European ancestry individuals, 1,539 Han Chinese ancestry individuals, 843 African American individuals, 445 Hispanic individuals 215,234 European ancestry individuals Affymetrix [12061510] (imputed) 1 bone density, lean body mass http://www.ebi.ac.uk/efo/EFO_0003923, http://www.ebi.ac.uk/efo/EFO_0004995 GCST011561 Genome-wide genotyping array 11335 2021-04-27 32929176 Feng GJ 2020-09-14 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32929176 Identification of pleiotropic loci underlying hip bone mineral density and trunk lean mass. Trunk lean mass 8,508 European ancestry individuals, 1,539 Han Chinese ancestry individuals, 843 African American individuals, 445 Hispanic individuals 215,234 European ancestry individuals Affymetrix [12061510] (imputed) 1 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST011560 Genome-wide genotyping array 11335 2021-04-27 32929176 Feng GJ 2020-09-14 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32929176 Identification of pleiotropic loci underlying hip bone mineral density and trunk lean mass. Bone mineral density 8,508 European ancestry individuals, 1,539 Han Chinese ancestry individuals, 843 African American individuals, 445 Hispanic individuals 215,234 European ancestry individuals Affymetrix [12061510] (imputed) 3 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST011559 Genome-wide genotyping array 11335 2021-06-04 33125279 Cordova-Palomera A 2020-10-30 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/33125279 Cardiac Imaging of Aortic Valve Area from 34,287 UK Biobank Participants Reveal Novel Genetic Associations and Shared Genetic Comorbidity with Multiple Disease Phenotypes. Aortic valve area 26,142 British ancestry individuals 8,145 European ancestry individuals Affymetrix [> 4100000] (imputed) 1 cardiovascular measurement http://www.ebi.ac.uk/efo/EFO_0004298 GCST011787 Genome-wide genotyping array 26142 2020-02-06 31840077 Couto Alves A 2019-09-04 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31840077 GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI. Peak weight velocity 7,215 European ancestry children 5,367 European ancestry children Affymetrix, Illumina [up to 2543888] (imputed) 0 growth rate measurement http://www.ebi.ac.uk/efo/EFO_0010572 GCST009552 Genome-wide genotyping array 7215 2020-02-06 31840077 Couto Alves A 2019-09-04 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31840077 GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI. Age at adiposity peak 6,222 European ancestry children NA Affymetrix, Illumina [up to 2543888] (imputed) 0 longitudinal BMI measurement, age at assessment http://www.ebi.ac.uk/efo/EFO_0005937, http://www.ebi.ac.uk/efo/EFO_0008007 GCST009553 Genome-wide genotyping array 6222 2020-02-06 31840077 Couto Alves A 2019-09-04 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31840077 GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI. BMI at adiposity peak 6,219 European ancestry children 16,550 European ancestry children Affymetrix, Illumina [up to 2543888] (imputed) 2 longitudinal BMI measurement http://www.ebi.ac.uk/efo/EFO_0005937 GCST009556 Genome-wide genotyping array 6219 2020-02-06 31840077 Couto Alves A 2019-09-04 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31840077 GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI. Age at adiposity rebound 6,051 European ancestry children 12,256 European ancestry children Affymetrix, Illumina [up to 2543888] (imputed) 2 longitudinal BMI measurement, age at assessment http://www.ebi.ac.uk/efo/EFO_0005937, http://www.ebi.ac.uk/efo/EFO_0008007 GCST009555 Genome-wide genotyping array 6051 2020-02-06 31840077 Couto Alves A 2019-09-04 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31840077 GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI. BMI at adiposity rebound 6,051 European ancestry children 12,192 European ancestry children Affymetrix, Illumina [up to 2543888] (imputed) 2 longitudinal BMI measurement http://www.ebi.ac.uk/efo/EFO_0005937 GCST009554 Genome-wide genotyping array 6051 2020-02-06 31840077 Couto Alves A 2019-09-04 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31840077 GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI. Peak height velocity 6,933 European ancestry children NA Affymetrix, Illumina [up to 2543888] (imputed) 0 growth rate measurement http://www.ebi.ac.uk/efo/EFO_0010572 GCST009551 Genome-wide genotyping array 6933 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Holdemanella abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011332 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Lachnospiraceae abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011333 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Oscillibacter abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011334 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Parabacteroides abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011335 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Paraprevotella abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011336 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Parasutterella abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011337 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Phascolarctobacterium abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011338 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Porphyromonadaceae abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011339 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Prevotella abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011340 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Prevotellaceae abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011341 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Roseburia abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011342 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Ruminococcaceae abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011343 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Ruminococcus abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011344 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Ruminococcus2 abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011345 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Subdoligranulum abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011346 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Sutterella abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011347 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. O_Bacteroidales abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011348 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. O_Burkholderiales abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011349 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_20 (Phascolarctobacterium) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011694 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_21 (Ruminococcaceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011695 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_22 (Sutterella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011696 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_23 (Barnesiella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011697 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_24 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011698 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_25 (Sutterella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011699 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_26 (Phascolarctobacterium) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011700 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_27 (Ruminococcaceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011701 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_28 (Holdemanella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011702 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_29 (Barnesiella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011703 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_3 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011704 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_30 (Paraprevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011705 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_31 (Ruminococcus) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011706 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_32 (Ruminococcaceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011707 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_33 (Paraprevotella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011708 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_34 (Phascolarctobacterium) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011709 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_35 (Alphaproteobacteria) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011710 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_36 (Aestuariispira) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011711 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_37 (Ruminococcaceae) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011712 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_38 (Ruminococcus) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011713 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_39 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011714 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_4 (Alistipes) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011715 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_40 (Barnesiella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011716 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_41 (Barnesiella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011717 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_42 (Alphaproteobacteria) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011718 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_43 (Parasutterella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011719 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_44 (Parasutterella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011720 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_45 (Clostridiales) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011721 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_46 (Sutterella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011722 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_47 (Parasutterella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011723 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_48 (Sutterella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011724 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_49 (Parasutterella) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011725 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. C_Gammaproteobacteria abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011307 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. C_Negativicutes abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011308 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. F_Acidaminococcaceae abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011309 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. F_Bacteroidaceae abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011310 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. F_Coriobacteriaceae abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011311 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. F_Erysipelotrichaceae abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011312 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. F_Lachnospiraceae abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011313 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. F_Porphyromonadaceae abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011314 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. F_Prevotellaceae abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011315 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. F_Rikenellaceae abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011316 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. F_Ruminococcaceae abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011317 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. F_Sutterellaceae abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011318 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Alistipes abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011319 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Alloprevotella abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011320 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Alphaproteobacteria abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011321 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Bacteroidales abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011322 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Bacteroides abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011323 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Bacteroidetes abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011324 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Barnesiella abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011325 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Catenibacterium abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011326 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Clostridiales abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011327 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Clostridium_XlVa abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011328 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Coprococcus abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011329 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Faecalibacterium abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011330 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. G_Firmicutes abundance 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011331 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_5 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011726 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_6 (Subdoligranulum) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011727 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_7 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011728 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_8 (Bacteroides) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011729 Genome-wide genotyping array 8956 2021-02-03 33462482 Ruhlemann MC 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462482 Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome. TestASV_9 (Alistipes) prevalence 8,956 German ancestry individuals NA NR [6900000] (imputed) 0 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90011730 Genome-wide genotyping array 8956 2020-05-19 31926482 Shen H 2020-01-11 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/31926482 Polygenic prediction and GWAS of depression, PTSD, and suicidal ideation/self-harm in a Peruvian cohort. Depression 1,076 Peruvian cases, 2,328 Peruvian controls NA NR [NR] 1 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST009978 Genome-wide genotyping array 3404 2020-05-19 31926482 Shen H 2020-01-11 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/31926482 Polygenic prediction and GWAS of depression, PTSD, and suicidal ideation/self-harm in a Peruvian cohort. Post-traumatic stress disorder 1,698 Peruvian cases, 1,716 Peruvian controls NA NR [3389129] (imputed) 4 post-traumatic stress disorder http://www.ebi.ac.uk/efo/EFO_0001358 GCST009977 Genome-wide genotyping array 3414 2020-05-19 31926482 Shen H 2020-01-11 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/31926482 Polygenic prediction and GWAS of depression, PTSD, and suicidal ideation/self-harm in a Peruvian cohort. Suicidal or self-harm ideation 522 Peruvian cases, 2,882 Peruvian controls NA NR [NR] 9 suicidal ideation http://www.ebi.ac.uk/efo/EFO_0004320 GCST009976 Genome-wide genotyping array 3404 2021-04-28 32939015 Zhu Z 2020-09-16 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32939015 A genome-wide association study reveals a substantial genetic basis underlying the Ebbinghaus illusion. Ebbinghaus illusion (underestimation) 1,986 Chinese ancestry individuals 839 Chinese ancestry individuals Illumina [at least 830937] (imputed) 36 visual perception measurement http://www.ebi.ac.uk/efo/EFO_0009700 GCST011567 Genome-wide genotyping array 1986 2021-04-28 32939015 Zhu Z 2020-09-16 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32939015 A genome-wide association study reveals a substantial genetic basis underlying the Ebbinghaus illusion. Ebbinghaus illusion (overestimation) 1,986 Chinese ancestry individuals 839 Chinese ancestry individuals Illumina [at least 830937] (imputed) 182 visual perception measurement http://www.ebi.ac.uk/efo/EFO_0009700 GCST011568 Genome-wide genotyping array 1986 2019-02-08 30593698 Hubel C 2018-12-28 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/30593698 Genomics of body fat percentage may contribute to sex bias in anorexia nervosa. Body fat percentage 70,700 European ancestry female individuals, 85,261 European ancestry male individuals NA Affymetrix [7794483] (imputed) 162 body fat percentage http://www.ebi.ac.uk/efo/EFO_0007800 GCST007064 Genome-wide genotyping array 155961 2019-02-08 30593698 Hubel C 2018-12-28 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/30593698 Genomics of body fat percentage may contribute to sex bias in anorexia nervosa. Fat-free mass 70,700 European ancestry female individuals, 85,261 European ancestry male individuals NA Affymetrix [7794483] (imputed) 407 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST007063 Genome-wide genotyping array 155961 2020-07-08 32047264 Cordova-Palomera A 2020-02-11 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32047264 Genetic control of variability in subcortical and intracranial volumes. Brain imaging measurements (variance) 25,575 European ancestry individuals NA NR [~ 5000000] (imputed) 2 neuroimaging measurement http://www.ebi.ac.uk/efo/EFO_0004346 GCST010149 Genome-wide genotyping array 25575 2020-07-08 32047264 Cordova-Palomera A 2020-02-11 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32047264 Genetic control of variability in subcortical and intracranial volumes. Brain imaging measurements (mean) 25,575 European ancestry individuals NA NR [~ 5000000] (imputed) 0 neuroimaging measurement http://www.ebi.ac.uk/efo/EFO_0004346 GCST010150 Genome-wide genotyping array 25575 2020-04-17 30371334 Tuteja S 2018-10-01 J Am Heart Assoc www.ncbi.nlm.nih.gov/pubmed/30371334 Genetic Variants Associated With Plasma Lipids Are Associated With the Lipid Response to Niacin. LDL cholesterol change in response to niacin in statin-treated individuals up to 1,034 European ancestry cases, up to 1,020 European ancestry controls NA Illumina [177496] 0 response to statin, LDL cholesterol change measurement, response to vitamin B3 http://purl.obolibrary.org/obo/GO_0036273, http://www.ebi.ac.uk/efo/EFO_0007804, http://www.ebi.ac.uk/efo/EFO_0010648 GCST009883 Targeted genotyping array [Metabochip] 2054 2020-04-17 30371334 Tuteja S 2018-10-01 J Am Heart Assoc www.ncbi.nlm.nih.gov/pubmed/30371334 Genetic Variants Associated With Plasma Lipids Are Associated With the Lipid Response to Niacin. Triglycerides levels in response to niacin in statin-treated individuals up to 1,034 European ancestry cases, up to 1,020 European ancestry controls NA Illumina [177496] 0 response to statin, triglyceride change measurement, response to vitamin B3 http://purl.obolibrary.org/obo/GO_0036273, http://www.ebi.ac.uk/efo/EFO_0007681, http://www.ebi.ac.uk/efo/EFO_0010648 GCST009884 Targeted genotyping array [Metabochip] 2054 2020-04-17 30371334 Tuteja S 2018-10-01 J Am Heart Assoc www.ncbi.nlm.nih.gov/pubmed/30371334 Genetic Variants Associated With Plasma Lipids Are Associated With the Lipid Response to Niacin. Total cholesterol change in response to niacin in statin-treated individuals up to 1,034 European ancestry cases, up to 1,020 European ancestry controls NA Illumina [177496] 0 response to statin, total cholesterol change measurement, response to vitamin B3 http://purl.obolibrary.org/obo/GO_0036273, http://www.ebi.ac.uk/efo/EFO_0007806, http://www.ebi.ac.uk/efo/EFO_0010648 GCST009882 Targeted genotyping array [Metabochip] 2054 2020-04-17 30371334 Tuteja S 2018-10-01 J Am Heart Assoc www.ncbi.nlm.nih.gov/pubmed/30371334 Genetic Variants Associated With Plasma Lipids Are Associated With the Lipid Response to Niacin. Lipoprotein (a) levels in response to niacin in statin-treated individuals up to 1,034 European ancestry cases, up to 1,020 European ancestry controls NA Illumina [177496] 1 response to statin, lipoprotein A measurement, response to vitamin B3 http://purl.obolibrary.org/obo/GO_0036273, http://www.ebi.ac.uk/efo/EFO_0006925, http://www.ebi.ac.uk/efo/EFO_0010648 GCST009881 Targeted genotyping array [Metabochip] 2054 2020-04-17 30371334 Tuteja S 2018-10-01 J Am Heart Assoc www.ncbi.nlm.nih.gov/pubmed/30371334 Genetic Variants Associated With Plasma Lipids Are Associated With the Lipid Response to Niacin. HDL cholesterol change in response to niacin in statin-treated individuals up to 1,034 European ancestry cases, up to 1,020 European ancestry controls NA Illumina [177496] 1 HDL cholesterol change measurement, response to statin, response to vitamin B3 http://www.ebi.ac.uk/efo/EFO_0007805, http://purl.obolibrary.org/obo/GO_0036273, http://www.ebi.ac.uk/efo/EFO_0010648 GCST009880 Targeted genotyping array [Metabochip] 2054 2019-09-23 31469255 Lule SA 2019-08-30 Mol Genet Genomic Med www.ncbi.nlm.nih.gov/pubmed/31469255 A genome-wide association and replication study of blood pressure in Ugandan early adolescents. Systolic blood pressure 815 African ancestry early adolescents NA Illumina [20074711] (imputed) 4 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST008749 Genome-wide genotyping array 815 2019-09-23 31469255 Lule SA 2019-08-30 Mol Genet Genomic Med www.ncbi.nlm.nih.gov/pubmed/31469255 A genome-wide association and replication study of blood pressure in Ugandan early adolescents. Diastolic blood pressure 815 African ancestry early adolescents NA Illumina [20074711] (imputed) 4 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST008750 Genome-wide genotyping array 815 2020-02-11 31465739 Liu M 2019-08-26 J Invest Dermatol www.ncbi.nlm.nih.gov/pubmed/31465739 A GENETIC VARIANT IN THE BCL2 GENE ASSOCIATES WITH ADALIMUMAB RESPONSE IN HIDRADENITIS SUPPURATIVA CLINICAL TRIALS AND REGULATES EXPRESSION OF BCL2. Response to adalimumab in hidradenitis suppurativa (abscess and inflammatory nodule count increase) 307 European ancestry individuals NR Illumina [6949858] (imputed) 1 response to TNF antagonist http://www.ebi.ac.uk/efo/EFO_0004653 GCST009601 Genome-wide genotyping array 307 2019-12-03 29083408 Liu DJ 2017-10-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29083408 Exome-wide association study of plasma lipids in >300,000 individuals. Total cholesterol levels up to 237,050 European ancestry individuals, up to 16,935 African ancestry individuals, up to 30,468 South Asian ancestry individuals, up to 8,287 East Asian ancestry individuals, 5,084 Hispanic individuals up to 286,268 European and unknown ancestry individuals Illumina [242289] 15 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST009145 Exome genotyping array [Exome array] 297824 2019-12-03 29083408 Liu DJ 2017-10-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29083408 Exome-wide association study of plasma lipids in >300,000 individuals. Total cholesterol levels up to 237,050 European ancestry individuals NA Illumina [242289] 16 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST009146 Exome genotyping array [Exome array] 237050 2019-12-03 29083408 Liu DJ 2017-10-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29083408 Exome-wide association study of plasma lipids in >300,000 individuals. Low density lipoprotein cholesterol levels up to 237,050 European ancestry individuals NA Illumina [242289] 19 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST009147 Exome genotyping array [Exome array] 237050 2019-12-03 29083408 Liu DJ 2017-10-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29083408 Exome-wide association study of plasma lipids in >300,000 individuals. High density lipoprotein cholesterol levels up to 237,050 European ancestry individuals NA Illumina [242289] 23 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST009148 Exome genotyping array [Exome array] 237050 2019-12-03 29083408 Liu DJ 2017-10-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29083408 Exome-wide association study of plasma lipids in >300,000 individuals. Triglyceride levels up to 237,050 European ancestry individuals NA Illumina [242289] 18 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST009149 Exome genotyping array [Exome array] 237050 2019-12-03 29083408 Liu DJ 2017-10-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29083408 Exome-wide association study of plasma lipids in >300,000 individuals. Low density lipoprotein cholesterol levels up to 237,050 European ancestry individuals, up to 16,935 African ancestry individuals, up to 30,468 South Asian ancestry individuals, up to 8,287 East Asian ancestry individuals, 5,084 Hispanic individuals up to 286,268 European and unknown ancestry individuals Illumina [242289] 17 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST009150 Exome genotyping array [Exome array] 297824 2019-12-03 29083408 Liu DJ 2017-10-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29083408 Exome-wide association study of plasma lipids in >300,000 individuals. High density lipoprotein cholesterol levels up to 237,050 European ancestry individuals, up to 16,935 African ancestry individuals, up to 30,468 South Asian ancestry individuals, up to 8,287 East Asian ancestry individuals, 5,084 Hispanic individuals up to 286,268 European and unknown ancestry individuals Illumina [242289] 24 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST009151 Exome genotyping array [Exome array] 297824 2019-12-03 29083408 Liu DJ 2017-10-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29083408 Exome-wide association study of plasma lipids in >300,000 individuals. Triglyceride levels up to 237,050 European ancestry individuals, up to 16,935 African ancestry individuals, up to 30,468 South Asian ancestry individuals, up to 8,287 East Asian ancestry individuals, 5,084 Hispanic individuals up to 286,268 European and unknown ancestry individuals Illumina [242289] 17 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST009152 Exome genotyping array [Exome array] 297824 2020-01-16 30954325 Kamboh MI 2019-03-11 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/30954325 Population-based genome-wide association study of cognitive decline in older adults free of dementia: identification of a novel locus for the attention domain. Age-related cognitive decline (global cognition) (slope of z-scores) 1,145 European ancestry individuals NA Illumina [5600000] (imputed) 5 cognitive decline measurement http://www.ebi.ac.uk/efo/EFO_0007710 GCST009444 Genome-wide genotyping array 1145 2020-01-16 30954325 Kamboh MI 2019-03-11 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/30954325 Population-based genome-wide association study of cognitive decline in older adults free of dementia: identification of a novel locus for the attention domain. Age-related cognitive decline (executive function) (slope of z-scores) 1,145 European ancestry individuals NA Illumina [5600000] (imputed) 9 cognitive decline measurement http://www.ebi.ac.uk/efo/EFO_0007710 GCST009442 Genome-wide genotyping array 1145 2020-01-16 30954325 Kamboh MI 2019-03-11 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/30954325 Population-based genome-wide association study of cognitive decline in older adults free of dementia: identification of a novel locus for the attention domain. Age-related cognitive decline (language) (slope of z-scores) 1,145 European ancestry individuals NA Illumina [5600000] (imputed) 28 cognitive decline measurement http://www.ebi.ac.uk/efo/EFO_0007710 GCST009439 Genome-wide genotyping array 1145 2020-01-16 30954325 Kamboh MI 2019-03-11 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/30954325 Population-based genome-wide association study of cognitive decline in older adults free of dementia: identification of a novel locus for the attention domain. Age-related cognitive decline (memory) (slope of z-scores) 1,145 European ancestry individuals NA Illumina [5600000] (imputed) 18 cognitive decline measurement http://www.ebi.ac.uk/efo/EFO_0007710 GCST009441 Genome-wide genotyping array 1145 2020-01-16 30954325 Kamboh MI 2019-03-11 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/30954325 Population-based genome-wide association study of cognitive decline in older adults free of dementia: identification of a novel locus for the attention domain. Age-related cognitive decline (visuospatial skill) (slope of z-scores) 1,145 European ancestry individuals NA Illumina [5600000] (imputed) 7 cognitive decline measurement http://www.ebi.ac.uk/efo/EFO_0007710 GCST009443 Genome-wide genotyping array 1145 2020-01-16 30954325 Kamboh MI 2019-03-11 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/30954325 Population-based genome-wide association study of cognitive decline in older adults free of dementia: identification of a novel locus for the attention domain. Age-related cognitive decline (attention/processing speed) (slope of z-scores) 1,145 European ancestry individuals NA Illumina [5600000] (imputed) 14 cognitive decline measurement http://www.ebi.ac.uk/efo/EFO_0007710 GCST009440 Genome-wide genotyping array 1145 2019-02-28 30541042 Walsh N 2018-12-12 J Natl Cancer Inst www.ncbi.nlm.nih.gov/pubmed/30541042 Agnostic Pathway/Gene Set Analysis of Genome-Wide Association Data Identifies Associations for Pancreatic Cancer. Pancreatic ductal adenocarcinoma 9,040 European ancestry cases, 12,496 European ancestry controls NA NR [NR] 9 pancreatic carcinoma http://www.ebi.ac.uk/efo/EFO_0002618 GCST007235 Genome-wide genotyping array 21536 2019-03-17 30552317 Guo W 2018-12-14 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/30552317 Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression. Response to ketamine in bipolar disorder or major depression (antidepressant effects) 157 European ancestry individuals NA Illumina [~ 6000000] (imputed) 7 depressive symptom measurement, response to ketamine http://www.ebi.ac.uk/efo/EFO_0007006, http://www.ebi.ac.uk/efo/EFO_0009748 GCST007316 Genome-wide genotyping array 157 2019-03-17 30552317 Guo W 2018-12-14 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/30552317 Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression. Response to ketamine in bipolar disorder or major depression (dissociation effects) 90 European ancestry individuals NA Illumina [~ 6000000] (imputed) 12 response to ketamine, dissociation measurement http://www.ebi.ac.uk/efo/EFO_0009748, http://www.ebi.ac.uk/efo/EFO_0009750 GCST007317 Genome-wide genotyping array 90 2019-09-03 29531327 Meijsen JJ 2018-03-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29531327 Phenotypic and genetic analysis of cognitive performance in Major Depressive Disorder in the Generation Scotland: Scottish Family Health Study. Cognitive performance (language ability) 488 European ancestry single-episode cases, 533 European ancestry recurrent episode cases, 5,991 European ancestry controls NA Illumina [557292] 0 cognitive function measurement, language measurement http://www.ebi.ac.uk/efo/EFO_0008354, http://www.ebi.ac.uk/efo/EFO_0007797 GCST008587 Genome-wide genotyping array 7012 2019-09-03 29531327 Meijsen JJ 2018-03-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29531327 Phenotypic and genetic analysis of cognitive performance in Major Depressive Disorder in the Generation Scotland: Scottish Family Health Study. Cognitive performance (processing speed) x major depressive disorder status interaction 533 European ancestry recurrent episode cases, 5,991 European ancestry controls NA Illumina [557292] 0 unipolar depression, information processing speed, cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0004363, http://www.ebi.ac.uk/efo/EFO_0008354 GCST008583 Genome-wide genotyping array 6524 2019-09-03 29531327 Meijsen JJ 2018-03-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29531327 Phenotypic and genetic analysis of cognitive performance in Major Depressive Disorder in the Generation Scotland: Scottish Family Health Study. Cognitive performance (language ability) x major depressive disorder status interaction 488 European ancestry single-episode cases, 533 European ancestry recurrent episode cases, 5,991 European ancestry controls NA Illumina [557292] 0 unipolar depression, cognitive function measurement, language measurement http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0008354, http://www.ebi.ac.uk/efo/EFO_0007797 GCST008584 Genome-wide genotyping array 7012 2019-09-03 29531327 Meijsen JJ 2018-03-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29531327 Phenotypic and genetic analysis of cognitive performance in Major Depressive Disorder in the Generation Scotland: Scottish Family Health Study. Cognitive performance (language ability) x major depressive disorder status interaction 533 European ancestry recurrent episode cases, 5,991 European ancestry controls NA Illumina [557292] 0 unipolar depression, cognitive function measurement, language measurement http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0008354, http://www.ebi.ac.uk/efo/EFO_0007797 GCST008585 Genome-wide genotyping array 6524 2019-09-03 29531327 Meijsen JJ 2018-03-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29531327 Phenotypic and genetic analysis of cognitive performance in Major Depressive Disorder in the Generation Scotland: Scottish Family Health Study. Cognitive performance (processing speed) x major depressive disorder type interaction 488 European ancestry single-episode cases, 533 European ancestry recurrent episode cases NA Illumina [557292] 0 unipolar depression, information processing speed, cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0004363, http://www.ebi.ac.uk/efo/EFO_0008354 GCST008586 Genome-wide genotyping array 1021 2019-09-03 29531327 Meijsen JJ 2018-03-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29531327 Phenotypic and genetic analysis of cognitive performance in Major Depressive Disorder in the Generation Scotland: Scottish Family Health Study. Cognitive performance (language ability) 533 European ancestry recurrent episode cases, 5,991 European ancestry controls NA Illumina [557292] 0 cognitive function measurement, language measurement http://www.ebi.ac.uk/efo/EFO_0008354, http://www.ebi.ac.uk/efo/EFO_0007797 GCST008588 Genome-wide genotyping array 6524 2019-09-03 29531327 Meijsen JJ 2018-03-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29531327 Phenotypic and genetic analysis of cognitive performance in Major Depressive Disorder in the Generation Scotland: Scottish Family Health Study. Cognitive performance (processing speed) in major depressive disorder 488 European ancestry single-episode cases, 533 European ancestry recurrent episode cases NA Illumina [557292] 0 information processing speed, cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0004363, http://www.ebi.ac.uk/efo/EFO_0008354 GCST008589 Genome-wide genotyping array 1021 2019-09-03 29531327 Meijsen JJ 2018-03-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29531327 Phenotypic and genetic analysis of cognitive performance in Major Depressive Disorder in the Generation Scotland: Scottish Family Health Study. Cognitive performance (processing speed) 533 European ancestry recurrent episode cases, 5,991 European ancestry controls NA Illumina [557292] 0 information processing speed, cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0004363, http://www.ebi.ac.uk/efo/EFO_0008354 GCST008590 Genome-wide genotyping array 6524 2019-09-20 30753327 Hishida A 2019-02-08 Carcinogenesis www.ncbi.nlm.nih.gov/pubmed/30753327 GWAS analysis reveals a significant contribution of PSCA to the risk of Heliobacter pylori-induced gastric atrophy. Anti-helicobacter pylori IgG seropositivity 1,239 Japanese ancestry cases, 2,146 Japanese ancestry controls 1,275 Japanese ancestry cases, 1,610 Japanese ancestry controls Illumina [575802] 0 Helicobacter pylori seropositivity http://www.ebi.ac.uk/efo/EFO_0009341 GCST008716 Genome-wide genotyping array 3385 2019-09-20 30753327 Hishida A 2019-02-08 Carcinogenesis www.ncbi.nlm.nih.gov/pubmed/30753327 GWAS analysis reveals a significant contribution of PSCA to the risk of Heliobacter pylori-induced gastric atrophy. Severe gastric atrophy 120 Japanese ancestry cases, 760 Japanese ancestry controls 435 Japanese ancestry cases, 184 Japanese ancestry controls Illumina [575802] 1 atrophic gastritis http://www.ebi.ac.uk/efo/EFO_1000826 GCST008713 Genome-wide genotyping array 880 2019-09-20 30753327 Hishida A 2019-02-08 Carcinogenesis www.ncbi.nlm.nih.gov/pubmed/30753327 GWAS analysis reveals a significant contribution of PSCA to the risk of Heliobacter pylori-induced gastric atrophy. Pepsinogen-I levels 3,385 Japanese ancestry individuals 2,885 Japanese ancestry individuals Illumina [575802] 0 pepsinogen-I measurement http://www.ebi.ac.uk/efo/EFO_0010148 GCST008709 Genome-wide genotyping array 3385 2019-09-20 30753327 Hishida A 2019-02-08 Carcinogenesis www.ncbi.nlm.nih.gov/pubmed/30753327 GWAS analysis reveals a significant contribution of PSCA to the risk of Heliobacter pylori-induced gastric atrophy. Pepsinogen I/II ratio 3,385 Japanese ancestry individuals 2,885 Japanese ancestry individuals Illumina [575802] 5 pepsinogen I/II ratio http://www.ebi.ac.uk/efo/EFO_0010149 GCST008712 Genome-wide genotyping array 3385 2019-09-20 30753327 Hishida A 2019-02-08 Carcinogenesis www.ncbi.nlm.nih.gov/pubmed/30753327 GWAS analysis reveals a significant contribution of PSCA to the risk of Heliobacter pylori-induced gastric atrophy. Gastric atrophy 479 Japanese ancestry cases, 760 Japanese ancestry controls 1,091 Japanese ancestry cases, 184 Japanese ancestry controls Illumina [575802] 1 atrophic gastritis http://www.ebi.ac.uk/efo/EFO_1000826 GCST008714 Genome-wide genotyping array 1239 2019-09-22 31423876 Singh S 2019-08-19 J Am Heart Assoc www.ncbi.nlm.nih.gov/pubmed/31423876 Genome-Wide Meta-Analysis of Blood Pressure Response to β1-Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies). Response to beta blocker use in hypertension (systolic blood pressure) 1,254 European ancestry individuals 1,552 European ancestry individuals, 315 African American individuals Affymetrix, Illumina [6596214] (imputed) 1 systolic blood pressure change measurement, response to beta blocker http://www.ebi.ac.uk/efo/EFO_0006944, http://www.ebi.ac.uk/efo/EFO_0007766 GCST008736 Genome-wide genotyping array 1254 2019-09-22 31423876 Singh S 2019-08-19 J Am Heart Assoc www.ncbi.nlm.nih.gov/pubmed/31423876 Genome-Wide Meta-Analysis of Blood Pressure Response to β1-Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies). Response to beta blocker use in hypertension (diastolic blood pressure) 1,254 European ancestry individuals 1,552 European ancestry individuals, 315 African American individuals Affymetrix, Illumina [6596214] (imputed) 0 diastolic blood pressure change measurement, response to beta blocker http://www.ebi.ac.uk/efo/EFO_0006945, http://www.ebi.ac.uk/efo/EFO_0007766 GCST008735 Genome-wide genotyping array 1254 2020-01-08 31504550 Bradfield JP 2019-07-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31504550 A Trans-ancestral Meta-Analysis of Genome-Wide Association Studies Reveals Loci Associated with Childhood Obesity. Childhood obesity 8,613 European ancestry cases, 3,213 African American cases, 69 Moroccan ancestry cases, 986 Hispanic/Latino cases, 124 East Asian ancestry cases, 12,696 European ancestry controls, 1,392 African American controls, 64 Moroccan ancestry controls, 993 Hispanic/Latino controls, 454 East Asian ancestry controls 921 European ancestry cases, 392 Southwest American Indian ancestry cases, 575 Hispanic cases, 1,930 European ancestry controls, 2,456 Southwest American Indian ancestry controls, 303 Hispanic controls Affymetrix, Illumina [up to 15123508] (imputed) 0 obesity http://www.ebi.ac.uk/efo/EFO_0001073 GCST009383 Genome-wide genotyping array 28604 2020-01-08 31504550 Bradfield JP 2019-07-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31504550 A Trans-ancestral Meta-Analysis of Genome-Wide Association Studies Reveals Loci Associated with Childhood Obesity. Childhood obesity 8,613 European ancestry cases, 3,213 African American cases, 69 Moroccan ancestry cases, 986 Hispanic/Latino cases, 124 East Asian ancestry cases, 12,696 European ancestry controls, 1,392 African American controls, 64 Moroccan ancestry controls, 993 Hispanic/Latino controls, 454 East Asian ancestry controls NA Affymetrix, Illumina [up to 15123508] (imputed) 57 obesity http://www.ebi.ac.uk/efo/EFO_0001073 GCST009382 Genome-wide genotyping array 28604 2019-10-17 31562322 Takata R 2019-09-27 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31562322 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population. Prostate cancer 5,088 Japanese ancestry cases, 10,682 Japanese ancestry controls 4,818 Japanese ancestry cases, 73,261 Japanese ancestry controls Illumina [7742602] (imputed) 37 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST008860 Genome-wide genotyping array 15770 2021-03-18 31482590 Joyner C 2019-09-04 Biom J www.ncbi.nlm.nih.gov/pubmed/31482590 A two-phase Bayesian methodology for the analysis of binary phenotypes in genome-wide association studies. Colorectal cancer 84 South East Asian ancestry cases, 89 South East Asian ancestry controls NA NR [495532] 0 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST011298 Genome-wide genotyping array 173 2020-02-06 31289819 Fitzgerald KC 2019-09-01 Brain www.ncbi.nlm.nih.gov/pubmed/31289819 Early complement genes are associated with visual system degeneration in multiple sclerosis. Decreased low contrast letter acuity in multiple sclerosis 582 European and unknown ancestry individuals 253 European and unknown ancestry individuals Illumina [5258576] (imputed) 6 visual acuity measurement http://www.ebi.ac.uk/efo/EFO_0008385 GCST009560 Genome-wide genotyping array 582 2020-02-06 31289819 Fitzgerald KC 2019-09-01 Brain www.ncbi.nlm.nih.gov/pubmed/31289819 Early complement genes are associated with visual system degeneration in multiple sclerosis. Rate of retinal ganglion cell–inner plexiform layer atrophy in multiple sclerosis 374 European and unknown ancestry individuals 376 individuals Illumina [503678] 0 eye measurement http://www.ebi.ac.uk/efo/EFO_0004731 GCST009559 Genome-wide genotyping array 374 2020-07-22 32308125 Wolking S 2020-04-20 Pharmacogenomics www.ncbi.nlm.nih.gov/pubmed/32308125 Pharmacoresponse in genetic generalized epilepsy: a genome-wide association study. Response to antiepileptic drugs in genetic generalized epilepsy 608 European ancestry responders, 278 European ancestry non-responders NA Affymetrix, Illumina [at least 3287443] (imputed) 4 response to anticonvulsant http://purl.obolibrary.org/obo/GO_0036277 GCST010296 Genome-wide genotyping array 886 2020-07-22 32308125 Wolking S 2020-04-20 Pharmacogenomics www.ncbi.nlm.nih.gov/pubmed/32308125 Pharmacoresponse in genetic generalized epilepsy: a genome-wide association study. Response to valproic acid in genetic generalized epilepsy 410 European ancestry responders, 155 European ancestry non-responders NA Affymetrix, Illumina [at least 3287443] (imputed) 3 response to anticonvulsant http://purl.obolibrary.org/obo/GO_0036277 GCST010295 Genome-wide genotyping array 565 2020-07-22 32308125 Wolking S 2020-04-20 Pharmacogenomics www.ncbi.nlm.nih.gov/pubmed/32308125 Pharmacoresponse in genetic generalized epilepsy: a genome-wide association study. Response to lamotrigine in genetic generalized epilepsy 137 European ancestry responders, 250 European ancestry non-responders NA Affymetrix, Illumina [at least 3287443] (imputed) 4 response to anticonvulsant http://purl.obolibrary.org/obo/GO_0036277 GCST010294 Genome-wide genotyping array 387 2020-07-22 32308125 Wolking S 2020-04-20 Pharmacogenomics www.ncbi.nlm.nih.gov/pubmed/32308125 Pharmacoresponse in genetic generalized epilepsy: a genome-wide association study. Response to levetiracetam in genetic generalized epilepsy 82 European ancestry responders, 127 European ancestry non-responders NA Affymetrix, Illumina [at least 3287443] (imputed) 9 response to anticonvulsant http://purl.obolibrary.org/obo/GO_0036277 GCST010293 Genome-wide genotyping array 209 2020-07-22 32308125 Wolking S 2020-04-20 Pharmacogenomics www.ncbi.nlm.nih.gov/pubmed/32308125 Pharmacoresponse in genetic generalized epilepsy: a genome-wide association study. Response to lamotrigine and valproic acid in genetic generalized epilepsy 31 European ancestry responders, 73 European ancestry non-responders NA Affymetrix, Illumina [at least 3287443] (imputed) 7 response to anticonvulsant http://purl.obolibrary.org/obo/GO_0036277 GCST010292 Genome-wide genotyping array 104 2020-07-12 29234017 Carayol J 2017-12-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29234017 Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator. Protein level change in low calorie diet obesity intervention 494 European ancestry individuals NA Illumina [4020654] (imputed) 8 response to low calorie diet, protein measurement http://www.ebi.ac.uk/efo/EFO_0010731, http://www.ebi.ac.uk/efo/EFO_0004747 GCST010197 Genome-wide genotyping array 494 2020-07-12 29234017 Carayol J 2017-12-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29234017 Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator. Protein levels in obesity 494 European ancestry individuals NA Illumina [4020654] (imputed) 58 protein measurement http://www.ebi.ac.uk/efo/EFO_0004747 GCST010196 Genome-wide genotyping array 494 2020-07-23 32321835 Alic L 2020-04-22 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/32321835 A genome-wide association study identifies key modulators of complement factor H binding to malondialdehyde-epitopes. Complement factor H binding to malondialdehyde 896 European ancestry major depressive disorder cases, 934 European ancestry individuals NA Illumina [4278941] (imputed) 5 complement factor H measurement, protein binding measurement http://www.ebi.ac.uk/efo/EFO_0008097, http://www.ebi.ac.uk/efo/EFO_0010742 GCST010306 Genome-wide genotyping array 1830 2020-07-23 32321835 Alic L 2020-04-22 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/32321835 A genome-wide association study identifies key modulators of complement factor H binding to malondialdehyde-epitopes. Complement factor H binding to malondialdehyde 934 European ancestry individuals NA Illumina [4278941] (imputed) 5 complement factor H measurement, protein binding measurement http://www.ebi.ac.uk/efo/EFO_0008097, http://www.ebi.ac.uk/efo/EFO_0010742 GCST010305 Genome-wide genotyping array 934 2020-07-23 32314116 Zhang H 2020-04-20 Osteoporos Int www.ncbi.nlm.nih.gov/pubmed/32314116 Pleiotropic loci underlying bone mineral density and bone size identified by a bivariate genome-wide association analysis. Bone mineral density (hip) 3,267 European ancestry individuals, 1,619 Chinese ancestry individuals, 843 African American individuals, 446 Hispanic individuals NA Affymetrix, Illumina [NR] (imputed) 4 hip bone mineral density http://www.ebi.ac.uk/efo/EFO_0007702 GCST010301 Genome-wide genotyping array 6175 2020-07-23 32314116 Zhang H 2020-04-20 Osteoporos Int www.ncbi.nlm.nih.gov/pubmed/32314116 Pleiotropic loci underlying bone mineral density and bone size identified by a bivariate genome-wide association analysis. Hip bone size 3,267 European ancestry individuals, 1,619 Chinese ancestry individuals, 843 African American individuals, 446 Hispanic individuals NA Affymetrix, Illumina [NR] (imputed) 33 hip bone size http://www.ebi.ac.uk/efo/EFO_0004844 GCST010300 Genome-wide genotyping array 6175 2020-07-23 32314116 Zhang H 2020-04-20 Osteoporos Int www.ncbi.nlm.nih.gov/pubmed/32314116 Pleiotropic loci underlying bone mineral density and bone size identified by a bivariate genome-wide association analysis. Bone mineral density (hip) and hip bone size 3,267 European ancestry individuals, 1,619 Chinese ancestry individuals, 843 African American individuals, 446 Hispanic individuals NA Affymetrix, Illumina [NR] (imputed) 34 hip bone mineral density, hip bone size http://www.ebi.ac.uk/efo/EFO_0007702, http://www.ebi.ac.uk/efo/EFO_0004844 GCST010299 Genome-wide genotyping array 6175 2020-06-16 32313116 Manry J 2020-04-20 Commun Biol www.ncbi.nlm.nih.gov/pubmed/32313116 Genome-wide association study of Buruli ulcer in rural Benin highlights role of two LncRNAs and the autophagy pathway. Buruli ulcer 402 Sub-Saharan African ancestry cases, 401 Sub-Saharan African ancestry controls 455 Sub-Saharan African ancestry cases, 238 Sub-Saharan African ancestry controls Illumina [10014109] (imputed) 1 Buruli Ulcer http://www.ebi.ac.uk/efo/EFO_1001281 GCST010077 Genome-wide genotyping array 803 2020-06-16 32313116 Manry J 2020-04-20 Commun Biol www.ncbi.nlm.nih.gov/pubmed/32313116 Genome-wide association study of Buruli ulcer in rural Benin highlights role of two LncRNAs and the autophagy pathway. Buruli ulcer (age at onset) 402 Sub-Saharan African ancestry cases 455 Sub-Saharan African ancestry cases Illumina [10014109] (imputed) 1 Buruli Ulcer, age at onset http://www.ebi.ac.uk/efo/EFO_1001281, http://www.ebi.ac.uk/efo/EFO_0004847 GCST010076 Genome-wide genotyping array 402 2020-06-24 32332799 Song W 2020-04-24 Sci Rep www.ncbi.nlm.nih.gov/pubmed/32332799 Genome-wide association analysis of insomnia using data from Partners Biobank. Insomnia 404,588 European ancestry individuals, 17,651 European, Hispanic and African ancestry individuals NA Illumina [5508534] (imputed) 17 insomnia http://www.ebi.ac.uk/efo/EFO_0004698 GCST010097 Genome-wide genotyping array 422239 2020-05-13 31816047 Boutin TS 2019-12-09 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31816047 Insights into the genetic basis of retinal detachment. Retinal detachment 2,893 British ancestry cases, 360,233 British ancestry controls NA Affymetrix, Illumina [7701827] (imputed) 3 retinal detachment http://www.ebi.ac.uk/efo/EFO_0005773 GCST009958 Genome-wide genotyping array 363126 2020-05-13 31816047 Boutin TS 2019-12-09 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31816047 Insights into the genetic basis of retinal detachment. Retinal detachment or retinal break 3,977 British ancestry cases, 360,233 British ancestry controls NA Affymetrix, Illumina [7701827] (imputed) 27 retinal detachment, retinal break http://www.ebi.ac.uk/efo/EFO_0005773, http://www.ebi.ac.uk/efo/EFO_0010698 GCST009959 Genome-wide genotyping array 364210 2020-05-13 31816047 Boutin TS 2019-12-09 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31816047 Insights into the genetic basis of retinal detachment. Retinal detachment with retinal break 1,380 British ancestry cases, 360,233 British ancestry controls NA Affymetrix, Illumina [7701827] (imputed) 1 rhegmatogenous retinal detachment http://www.ebi.ac.uk/efo/EFO_0005240 GCST009961 Genome-wide genotyping array 361613 2020-05-13 31816047 Boutin TS 2019-12-09 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31816047 Insights into the genetic basis of retinal detachment. Retinal detachment or retinal break 6,141 European ancestry cases, 59,475 European ancestry controls 9,171 European ancestry cases, 406,168 European ancestry controls Affymetrix, Illumina [7581674] (imputed) 2 retinal detachment, retinal break http://www.ebi.ac.uk/efo/EFO_0005773, http://www.ebi.ac.uk/efo/EFO_0010698 GCST009960 Genome-wide genotyping array 65616 2020-05-13 31816047 Boutin TS 2019-12-09 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31816047 Insights into the genetic basis of retinal detachment. High myopia 2,737 British ancestry cases, 47,635 British ancestry controls NA Affymetrix [NR] (imputed) 17 Myopia http://purl.obolibrary.org/obo/HP_0000545 GCST009962 Genome-wide genotyping array 50372 2020-05-13 31816047 Boutin TS 2019-12-09 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31816047 Insights into the genetic basis of retinal detachment. Cataracts (operation) 21,679 British ancestry cases, 387,283 British ancestry controls NA Affymetrix [NR] (imputed) 20 cataract http://www.ebi.ac.uk/efo/EFO_0001059 GCST009963 Genome-wide genotyping array 408962 2020-06-05 32310270 Foo JN 2020-04-20 JAMA Neurol www.ncbi.nlm.nih.gov/pubmed/32310270 Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans: A Genome-Wide Association Study. Parkinson's disease 6,724 East Asian ancestry cases, 24,851 East Asian ancestry controls 57,545 European ancestry cases, 1,868,816 European ancestry controls, 988 Japanese ancestry cases, 2,521 Japanese ancestry controls Illumina [5843213] (imputed) 10 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST010049 Genome-wide genotyping array 31575 2020-06-03 32310165 Kim BH 2020-04-09 J Alzheimers Dis www.ncbi.nlm.nih.gov/pubmed/32310165 Identification of Novel Genes Associated with Cortical Thickness in Alzheimer's Disease: Systems Biology Approach to Neuroimaging Endophenotype. Cortical thickness 919 European ancestry individuals NA Illumina [3041429] (imputed) 2 cortical thickness http://www.ebi.ac.uk/efo/EFO_0004840 GCST010041 Genome-wide genotyping array 919 2020-01-07 31719535 Noordam R 2019-11-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31719535 Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration. HDL cholesterol levels x long total sleep time interaction (2df test) 2,933 African American long sleepers, 364 Chinese ancestry long sleepers, 112 Asian ancestry long sleepers, up to 7,870 European ancestry long sleepers, 1,038 Hispanic/Latino long sleepers, up to 11,975 African American controls, 1,449 Chinese ancestry controls, 454 Asian ancestry controls, at least 32,171 European ancestry controls, 4,091 Hispanic/Latino controls at least 217 African American long sleepers, 616 East Asian ancestry long sleepers, up to 9,486 European ancestry long sleepers, 2,515 Hispanic long sleepers, at least 929 African American controls, 2,517 East Asian ancestry controls, up to 38,126 European ancestry controls, 10,063 Hispanic controls Affymetrix, Illumina [up to 2533153] (imputed) 84 sleep duration, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0005271, http://www.ebi.ac.uk/efo/EFO_0004612 GCST009368 Genome-wide genotyping array 62457 2020-01-07 31719535 Noordam R 2019-11-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31719535 Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration. Triglyceride levels x long total sleep time interaction (1df test) at least 2,926 African American long sleepers, 364 Chinese ancestry long sleepers, 112 Asian ancestry long sleepers, at least 7,664 European ancestry long sleepers, 1,038 Hispanic/Latino long sleepers, up to 11,906 African American controls, 1,449 Chinese ancestry controls, 454 Asian ancestry controls, at least 31,986 European ancestry controls, 4,091 Hispanic/Latino controls at least 217 African American long sleepers, 317 East Asian ancestry long sleepers, up to 5,171 European ancestry long sleepers, 2,515 Hispanic long sleepers, at least 928 African American controls, 1,301 East Asian ancestry controls, up to 20,961 European ancestry controls, 10,064 Hispanic controls Affymetrix, Illumina [up to 2533153] (imputed) 2 sleep duration, triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0005271, http://www.ebi.ac.uk/efo/EFO_0004530 GCST009358 Genome-wide genotyping array 61990 2020-01-07 31719535 Noordam R 2019-11-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31719535 Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration. HDL cholesterol levels x short total sleep time interaction (2df test) 3,007 African American short sleepers, 369 Chinese ancestry short sleepers, 114 Asian ancestry short sleepers, at least 8,474 European ancestry short sleepers, 1,082 Hispanic/Latino short sleepers, up to 11,901 African American controls, 1,444 Chinese ancestry controls, 452 Asian ancestry controls, at least 31,567 European ancestry controls, 4,047 Hispanic/Latino controls up to 221 African American short sleepers, 629 East Asian ancestry short sleepers, up to 9,585 European ancestry short sleepers, 2,517 Hispanic short sleepers, at least 925 African American controls, 2,504 East Asian ancestry controls, up to 38,027 European ancestry controls, 10,061 Hispanic controls Affymetrix, Illumina [up to 2533153] (imputed) 91 sleep duration, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0005271, http://www.ebi.ac.uk/efo/EFO_0004612 GCST009367 Genome-wide genotyping array 62457 2020-01-07 31719535 Noordam R 2019-11-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31719535 Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration. LDL cholesterol levels x long total sleep time interaction (2df test) 2,913 African American long sleepers, 358 Chinese ancestry long sleepers, 110 Asian ancestry long sleepers, 7,583 European ancestry long sleepers, 1,036 Hispanic/Latino long sleepers, up to 11,862 African American controls, 1,432 Chinese ancestry controls, 444 Asian ancestry controls, at least 31,744 European ancestry controls, 4,066 Hispanic/Latino controls at least 214 African American long sleepers, 616 East Asian ancestry long sleepers, up to 6,657 European ancestry long sleepers, 2,457 Hispanic long sleepers, at least 913 African American controls, 2,517 East Asian ancestry controls, up to 26,868 European ancestry controls, 9,870 Hispanic controls Affymetrix, Illumina [up to 2533153] (imputed) 61 sleep duration, low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0005271, http://www.ebi.ac.uk/efo/EFO_0004611 GCST009366 Genome-wide genotyping array 61548 2020-01-07 31719535 Noordam R 2019-11-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31719535 Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration. LDL cholesterol levels x short total sleep time interaction (2df test) 2,974 African American short sleepers, 365 Chinese ancestry short sleepers, 110 Asian ancestry short sleepers, at least 8,230 European ancestry short sleepers, 1,079 Hispanic/Latino short sleepers, 11,801 African American controls, 1,425 Chinese ancestry controls, 444 Asian ancestry controls, at least 31,097 European ancestry controls, 4,023 Hispanic/Latino controls at least 214 African American short sleepers, 629 East Asian ancestry short sleepers, up to 6,761 European ancestry short sleepers, 2,473 Hispanic short sleepers, at least 913 African American controls, 2,504 East Asian ancestry controls, up to 26,764 European ancestry controls, 9,854 Hispanic controls Affymetrix, Illumina [up to 2533153] (imputed) 71 sleep duration, low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0005271, http://www.ebi.ac.uk/efo/EFO_0004611 GCST009365 Genome-wide genotyping array 61548 2020-01-07 31719535 Noordam R 2019-11-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31719535 Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration. Triglyceride levels x long total sleep time interaction (2df test) at least 2,926 African American long sleepers, 364 Chinese ancestry long sleepers, 112 Asian ancestry long sleepers, at least 7,664 European ancestry long sleepers, 1,038 Hispanic/Latino long sleepers, up to 11,906 African American controls, 1,449 Chinese ancestry controls, 454 Asian ancestry controls, at least 31,986 European ancestry controls, 4,091 Hispanic/Latino controls at least 217 African American long sleepers, 317 East Asian ancestry long sleepers, up to 5,171 European ancestry long sleepers, 2,515 Hispanic long sleepers, at least 928 African American controls, 1,301 East Asian ancestry controls, up to 20,961 European ancestry controls, 10,064 Hispanic controls Affymetrix, Illumina [up to 2533153] (imputed) 58 sleep duration, triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0005271, http://www.ebi.ac.uk/efo/EFO_0004530 GCST009364 Genome-wide genotyping array 61990 2020-01-07 31719535 Noordam R 2019-11-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31719535 Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration. Triglyceride levels x short total sleep time interaction (2df test) 2,990 African American short sleepers, 369 Chinese ancestry short sleepers, 114 Asian ancestry short sleepers, at least 8,300 European ancestry short sleepers, 1,082 Hispanic/Latino short sleepers, at least 11,842 African American controls, 1,444 Chinese ancestry controls, 452 Asian ancestry controls, at least 31,350 European ancestry controls, 4,047 Hispanic/Latino controls at least 220 African American short sleepers, 326 East Asian ancestry short sleepers, up to 5,288 European ancestry short sleepers, 2,517 Hispanic short sleepers, at least 925 African American controls, 1,292 East Asian ancestry controls, up to 20,844 European ancestry controls, 10,062 Hispanic controls Affymetrix, Illumina [up to 2533153] (imputed) 63 sleep duration, triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0005271, http://www.ebi.ac.uk/efo/EFO_0004530 GCST009363 Genome-wide genotyping array 61990 2020-01-07 31719535 Noordam R 2019-11-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31719535 Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration. HDL cholesterol levels x long total sleep time interaction (1df test) 2,933 African American long sleepers, 364 Chinese ancestry long sleepers, 112 Asian ancestry long sleepers, up to 7,870 European ancestry long sleepers, 1,038 Hispanic/Latino long sleepers, up to 11,975 African American controls, 1,449 Chinese ancestry controls, 454 Asian ancestry controls, at least 32,171 European ancestry controls, 4,091 Hispanic/Latino controls at least 217 African American long sleepers, 616 East Asian ancestry long sleepers, up to 9,486 European ancestry long sleepers, 2,515 Hispanic long sleepers, at least 929 African American controls, 2,517 East Asian ancestry controls, up to 38,126 European ancestry controls, 10,063 Hispanic controls Affymetrix, Illumina [up to 2533153] (imputed) 3 sleep duration, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0005271, http://www.ebi.ac.uk/efo/EFO_0004612 GCST009362 Genome-wide genotyping array 62457 2020-01-07 31719535 Noordam R 2019-11-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31719535 Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration. Triglyceride levels 14,832 African American individuals, 1,813 Chinese ancestry individuals, 566 Asian ancestry individuals, 39,650 European ancestry individuals, 5,129 Hispanic/Latino individuals NA Affymetrix, Illumina [up to 2533153] (imputed) 1 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST009370 Genome-wide genotyping array 61990 2020-01-07 31719535 Noordam R 2019-11-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31719535 Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration. Triglyceride levels x short total sleep time interaction (1df test) 2,990 African American short sleepers, 369 Chinese ancestry short sleepers, 114 Asian ancestry short sleepers, at least 8,300 European ancestry short sleepers, 1,082 Hispanic/Latino short sleepers, at least 11,842 African American controls, 1,444 Chinese ancestry controls, 452 Asian ancestry controls, at least 31,350 European ancestry controls, 4,047 Hispanic/Latino controls at least 220 African American short sleepers, 326 East Asian ancestry short sleepers, up to 5,288 European ancestry short sleepers, 2,517 Hispanic short sleepers, at least 925 African American controls, 1,292 East Asian ancestry controls, up to 20,844 European ancestry controls, 10,062 Hispanic controls Affymetrix, Illumina [up to 2533153] (imputed) 2 sleep duration, triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0005271, http://www.ebi.ac.uk/efo/EFO_0004530 GCST009369 Genome-wide genotyping array 61990 2019-12-17 31719535 Noordam R 2019-11-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31719535 Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration. HDL cholesterol levels 14,908 African American individuals, 1,813 Chinese ancestry individuals, 566 Asian ancestry individuals, 40,041 European ancestry individuals, 5,129 Hispanic/Latino individuals NA Affymetrix, Illumina [up to 2533153] (imputed) 0 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST009316 Genome-wide genotyping array 62457 2020-01-07 31719535 Noordam R 2019-11-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31719535 Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration. HDL cholesterol levels x short total sleep time interaction (1df test) 3,007 African American short sleepers, 369 Chinese ancestry short sleepers, 114 Asian ancestry short sleepers, at least 8,474 European ancestry short sleepers, 1,082 Hispanic/Latino short sleepers, up to 11,901 African American controls, 1,444 Chinese ancestry controls, 452 Asian ancestry controls, at least 31,567 European ancestry controls, 4,047 Hispanic/Latino controls up to 221 African American short sleepers, 629 East Asian ancestry short sleepers, up to 9,585 European ancestry short sleepers, 2,517 Hispanic short sleepers, at least 925 African American controls, 2,504 East Asian ancestry controls, up to 38,027 European ancestry controls, 10,061 Hispanic controls Affymetrix, Illumina [up to 2533153] (imputed) 1 sleep duration, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0005271, http://www.ebi.ac.uk/efo/EFO_0004612 GCST009361 Genome-wide genotyping array 62457 2020-01-07 31719535 Noordam R 2019-11-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31719535 Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration. LDL cholesterol levels x long total sleep time interaction (1df test) 2,913 African American long sleepers, 358 Chinese ancestry long sleepers, 110 Asian ancestry long sleepers, 7,583 European ancestry long sleepers, 1,036 Hispanic/Latino long sleepers, up to 11,862 African American controls, 1,432 Chinese ancestry controls, 444 Asian ancestry controls, at least 31,744 European ancestry controls, 4,066 Hispanic/Latino controls at least 214 African American long sleepers, 616 East Asian ancestry long sleepers, up to 6,657 European ancestry long sleepers, 2,457 Hispanic long sleepers, at least 913 African American controls, 2,517 East Asian ancestry controls, up to 26,868 European ancestry controls, 9,870 Hispanic controls Affymetrix, Illumina [up to 2533153] (imputed) 3 sleep duration, low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0005271, http://www.ebi.ac.uk/efo/EFO_0004611 GCST009360 Genome-wide genotyping array 61548 2019-12-17 31719535 Noordam R 2019-11-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31719535 Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration. LDL cholesterol levels 14,775 African American individuals, 1,790 Chinese ancestry individuals, 554 Asian ancestry individuals, 39,327 European ancestry individuals, 5,102 Hispanic/Latino individuals NA Affymetrix, Illumina [up to 2533153] (imputed) 0 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST009317 Genome-wide genotyping array 61548 2020-01-07 31719535 Noordam R 2019-11-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31719535 Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration. LDL cholesterol levels x short total sleep time interaction (1df test) 2,974 African American short sleepers, 365 Chinese ancestry short sleepers, 110 Asian ancestry short sleepers, at least 8,230 European ancestry short sleepers, 1,079 Hispanic/Latino short sleepers, 11,801 African American controls, 1,425 Chinese ancestry controls, 444 Asian ancestry controls, at least 31,097 European ancestry controls, 4,023 Hispanic/Latino controls at least 214 African American short sleepers, 629 East Asian ancestry short sleepers, up to 6,761 European ancestry short sleepers, 2,473 Hispanic short sleepers, at least 913 African American controls, 2,504 East Asian ancestry controls, up to 26,764 European ancestry controls, 9,854 Hispanic controls Affymetrix, Illumina [up to 2533153] (imputed) 2 sleep duration, low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0005271, http://www.ebi.ac.uk/efo/EFO_0004611 GCST009359 Genome-wide genotyping array 61548 2021-01-27 32324875 Campbell PT 2020-04-23 J Natl Cancer Inst www.ncbi.nlm.nih.gov/pubmed/32324875 Association of body mass index with colorectal cancer risk by genome-wide variants. Colorectal cancer x BMI interaction (2df) 14,059 European ancestry cases, 14,416 European ancestry controls NA Affymetrix, Illumina [2700000] (imputed) 1 colorectal adenocarcinoma, body mass index http://www.ebi.ac.uk/efo/EFO_0000365, http://www.ebi.ac.uk/efo/EFO_0004340 GCST010992 Genome-wide genotyping array 28475 2020-06-01 32173896 Maffioletti E 2020-03-16 Drug Dev Res www.ncbi.nlm.nih.gov/pubmed/32173896 Genetic determinants of circulating VEGF levels in major depressive disorder and electroconvulsive therapy response. Vascular endothelial growth factor levels in major depressive disorder 121 European ancestry individuals NA Illumina [677673] 1 vascular endothelial growth factor measurement http://www.ebi.ac.uk/efo/EFO_0004762 GCST010036 Genome-wide genotyping array 121 2020-06-01 32173896 Maffioletti E 2020-03-16 Drug Dev Res www.ncbi.nlm.nih.gov/pubmed/32173896 Genetic determinants of circulating VEGF levels in major depressive disorder and electroconvulsive therapy response. Vascular endothelial growth factor levels 145 European ancestry individuals NA Affymetrix [646354] 1 vascular endothelial growth factor measurement http://www.ebi.ac.uk/efo/EFO_0004762 GCST010037 Genome-wide genotyping array 145 2020-05-09 22936693 Juran BD 2012-08-29 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22936693 Immunochip analyses identify a novel risk locus for primary biliary cirrhosis at 13q14, multiple independent associations at four established risk loci and epistasis between 1p31 and 7q32 risk variants. Primary biliary cirrhosis 2,216 European ancestry cases, 5,594 Europen ancestry controls NA Illumina [109812] 24 primary biliary cirrhosis http://www.ebi.ac.uk/efo/EFO_1001486 GCST009956 Targeted genotyping array [ImmunoChip] 7810 2020-05-12 32281736 Fan R 2020-04-13 Addict Biol www.ncbi.nlm.nih.gov/pubmed/32281736 Gene-based association analysis reveals involvement of LAMA5 and cell adhesion pathways in nicotine dependence in African- and European-American samples. Nicotine dependence 1,644 African American cases, 1,727 African American controls 852 Europen ancestry cases, 720 European ancestry controls Illumina [up to 111643] 1 nicotine dependence http://www.ebi.ac.uk/efo/EFO_0003768 GCST009957 Exome genotyping array [Exome array] 3371 2020-05-22 32266149 He Y 2020-03-20 Front Oncol www.ncbi.nlm.nih.gov/pubmed/32266149 Genetic Variants Were Associated With the Prognosis of Head and Neck Squamous Carcinoma. Head and neck squamous cell carcinoma 261 Chinese ancestry cases 525 Chinese ancestry cases Illumina [247870] 2 head and neck squamous cell carcinoma http://www.ebi.ac.uk/efo/EFO_0000181 GCST009985 Exome genotyping array [Exome array] 261 2020-03-10 32060260 Campos AI 2020-02-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32060260 Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank. Snoring 151,836 British ancestry cases, 255,230 British ancestry controls NA NR [11010159] (imputed) 35 snoring measurement http://www.ebi.ac.uk/efo/EFO_0008341 GCST009761 Genome-wide genotyping array 407066 2020-03-10 32060260 Campos AI 2020-02-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32060260 Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank. Snoring 90,806 British ancestry male cases, 99,165 British ancestry male controls NA NR [11010159] (imputed) 11 snoring measurement http://www.ebi.ac.uk/efo/EFO_0008341 GCST009762 Genome-wide genotyping array 189971 2020-03-10 32060260 Campos AI 2020-02-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32060260 Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank. Snoring 61,792 British ancestry female cases, 156,554 British ancestry female controls NA NR [11010159] (imputed) 28 snoring measurement http://www.ebi.ac.uk/efo/EFO_0008341 GCST009763 Genome-wide genotyping array 218346 2020-03-10 32060260 Campos AI 2020-02-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32060260 Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank. Snoring 152,302 British ancestry cases, 256,015 British ancestry controls NA NR [11010159] (imputed) 41 snoring measurement http://www.ebi.ac.uk/efo/EFO_0008341 GCST009760 Genome-wide genotyping array 408317 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Red cell distribution width up to 7,526 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 2 red blood cell distribution width http://www.ebi.ac.uk/efo/EFO_0005192 GCST009032 Genome-wide genotyping array, Genome-wide sequencing 7526 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Hematocrit up to 7,526 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 0 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST009033 Genome-wide genotyping array, Genome-wide sequencing 7526 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Hemoglobin levels up to 7,526 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 0 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST009034 Genome-wide genotyping array, Genome-wide sequencing 7526 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Mean platelet volume up to 6,407 African ancestry individuals NA Affymetrix, Illumina [at least 20594556] (imputed) 1 mean platelet volume http://www.ebi.ac.uk/efo/EFO_0004584 GCST009035 Genome-wide genotyping array, Genome-wide sequencing 6407 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Platelet count up to 7,526 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 0 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST009036 Genome-wide genotyping array, Genome-wide sequencing 7526 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Lymphocyte counts up to 7,526 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 0 lymphocyte count http://www.ebi.ac.uk/efo/EFO_0004587 GCST009037 Genome-wide genotyping array, Genome-wide sequencing 7526 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Monocyte count up to 7,526 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 1 monocyte count http://www.ebi.ac.uk/efo/EFO_0005091 GCST009038 Genome-wide genotyping array, Genome-wide sequencing 7526 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Basophil count up to 7,526 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 0 basophil count http://www.ebi.ac.uk/efo/EFO_0005090 GCST009039 Genome-wide genotyping array, Genome-wide sequencing 7526 2019-11-18 31675503 Gurdasani D 2019-10-01 Cell www.ncbi.nlm.nih.gov/pubmed/31675503 Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa. Neutrophil count up to 7,526 African ancestry individuals NA Affymetrix, Illumina [at least 24423923] (imputed) 2 neutrophil count http://www.ebi.ac.uk/efo/EFO_0004833 GCST009040 Genome-wide genotyping array, Genome-wide sequencing 7526 2020-01-27 31647587 Willems EL 2019-10-24 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31647587 Transethnic meta-analysis of metabolic syndrome in a multiethnic study. Waist circumference 281 African American individuals from 73 families, 516 European American individuals from 75 families, 125 East Asian ancestry individuals from 15 families, 598 Mexican American individuals from 96 families NA Illumina [3153931] (imputed) 2 waist circumference http://www.ebi.ac.uk/efo/EFO_0004342 GCST009504 Genome-wide genotyping array 1779 2020-01-27 31647587 Willems EL 2019-10-24 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31647587 Transethnic meta-analysis of metabolic syndrome in a multiethnic study. Systolic blood pressure 281 African American individuals from 73 families, 516 European American individuals from 75 families, 125 East Asian ancestry individuals from 15 families, 598 Mexican American individuals from 96 families NA Illumina [3153931] (imputed) 2 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST009506 Genome-wide genotyping array 1779 2020-01-27 31647587 Willems EL 2019-10-24 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31647587 Transethnic meta-analysis of metabolic syndrome in a multiethnic study. Diastolic blood pressure 281 African American individuals from 73 families, 516 European American individuals from 75 families, 125 East Asian ancestry individuals from 15 families, 598 Mexican American individuals from 96 families NA Illumina [3153931] (imputed) 2 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST009508 Genome-wide genotyping array 1779 2020-01-27 31647587 Willems EL 2019-10-24 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31647587 Transethnic meta-analysis of metabolic syndrome in a multiethnic study. Triglyceride levels 281 African American individuals from 73 families, 516 European American individuals from 75 families, 125 East Asian ancestry individuals from 15 families, 598 Mexican American individuals from 96 families NA Illumina [3153931] (imputed) 8 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST009507 Genome-wide genotyping array 1779 2020-01-27 31647587 Willems EL 2019-10-24 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31647587 Transethnic meta-analysis of metabolic syndrome in a multiethnic study. High density lipoprotein cholesterol levels 281 African American individuals from 73 families, 516 European American individuals from 75 families, 125 East Asian ancestry individuals from 15 families, 598 Mexican American individuals from 96 families NA Illumina [3153931] (imputed) 2 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST009509 Genome-wide genotyping array 1779 2020-01-27 31647587 Willems EL 2019-10-24 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31647587 Transethnic meta-analysis of metabolic syndrome in a multiethnic study. Fasting blood glucose 281 African American individuals from 73 families, 516 European American individuals from 75 families, 125 East Asian ancestry individuals from 15 families, 598 Mexican American individuals from 96 families NA Illumina [3153931] (imputed) 0 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST009510 Genome-wide genotyping array 1779 2020-01-27 31647587 Willems EL 2019-10-24 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31647587 Transethnic meta-analysis of metabolic syndrome in a multiethnic study. Fasting blood insulin 281 African American individuals from 73 families, 516 European American individuals from 75 families, 125 East Asian ancestry individuals from 15 families, 598 Mexican American individuals from 96 families NA Illumina [3153931] (imputed) 0 fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004466 GCST009511 Genome-wide genotyping array 1779 2020-01-27 31647587 Willems EL 2019-10-24 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31647587 Transethnic meta-analysis of metabolic syndrome in a multiethnic study. Weight 281 African American individuals from 73 families, 516 European American individuals from 75 families, 125 East Asian ancestry individuals from 15 families, 598 Mexican American individuals from 96 families NA Illumina [3153931] (imputed) 1 body weight http://www.ebi.ac.uk/efo/EFO_0004338 GCST009505 Genome-wide genotyping array 1779 2019-04-30 25043022 Moltke I 2014-06-18 Nature www.ncbi.nlm.nih.gov/pubmed/25043022 A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes. Two-hour insulin response 2,540 Greenlandic ancestry individuals 845 Greenlandic ancestry individuals Illumina [up to 196725] 0 insulin response measurement http://www.ebi.ac.uk/efo/EFO_0008473 GCST007669 Targeted genotyping array [Cardio-MetaboChip] 2540 2019-04-30 25043022 Moltke I 2014-06-18 Nature www.ncbi.nlm.nih.gov/pubmed/25043022 A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes. Fasting blood glucose 2,575 Greenlandic ancestry individuals 1,064 Greenlandic ancestry individuals Illumina [up to 196725] 0 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST007670 Targeted genotyping array [Cardio-MetaboChip] 2575 2019-04-30 25043022 Moltke I 2014-06-18 Nature www.ncbi.nlm.nih.gov/pubmed/25043022 A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes. Fasting blood insulin 2,575 Greenlandic ancestry individuals 1,062 Greenlandic ancestry individuals Illumina [up to 196725] 0 fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004466 GCST007671 Targeted genotyping array [Cardio-MetaboChip] 2575 2019-04-30 25043022 Moltke I 2014-06-18 Nature www.ncbi.nlm.nih.gov/pubmed/25043022 A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes. Two-hour glucose 2,540 Greenlandic ancestry individuals 845 Greenlandic ancestry individuals Illumina [up to 196725] 1 glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0004307 GCST007668 Targeted genotyping array [Cardio-MetaboChip] 2540 2020-01-27 31681408 Yang XL 2019-10-11 Front Genet www.ncbi.nlm.nih.gov/pubmed/31681408 Three Novel Loci for Infant Head Circumference Identified by a Joint Association Analysis. Birth length (MTAG) up to 182,902 European ancestry individuals NA NR [1977400] (imputed) 27 body height at birth http://www.ebi.ac.uk/efo/EFO_0006784 GCST009499 Genome-wide genotyping array 182902 2020-01-27 31681408 Yang XL 2019-10-11 Front Genet www.ncbi.nlm.nih.gov/pubmed/31681408 Three Novel Loci for Infant Head Circumference Identified by a Joint Association Analysis. Infant head circumference (MTAG) up to 182,902 European ancestry individuals NA NR [1977400] (imputed) 11 infant head circumference http://www.ebi.ac.uk/efo/EFO_0004577 GCST009500 Genome-wide genotyping array 182902 2020-01-27 31681408 Yang XL 2019-10-11 Front Genet www.ncbi.nlm.nih.gov/pubmed/31681408 Three Novel Loci for Infant Head Circumference Identified by a Joint Association Analysis. Birth weight (MTAG) up to 182,902 European ancestry individuals NA NR [1977400] (imputed) 40 birth weight http://www.ebi.ac.uk/efo/EFO_0004344 GCST009498 Genome-wide genotyping array 182902 2021-06-04 31697830 Aksit MA 2019-10-19 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/31697830 Genetic modifiers of cystic fibrosis-related diabetes have extensive overlap with type 2 diabetes and related traits. Cystic fibrosis-related diabetes in cystic fibrosis 1,341 European and unknown ancestry cases, 4,399 European and unknown ancestry controls 204 European and unknown ancestry cases, 387 European and unknown ancestry controls Illumina [9157530] (imputed) 0 diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0000400 GCST011784 Genome-wide genotyping array 5740 2019-09-13 26423011 Wain LV 2015-09-27 Lancet Respir Med www.ncbi.nlm.nih.gov/pubmed/26423011 Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank. Lung function in heavy smokers (low FEV1 vs high FEV1) 9,748 European ancestry individuals with low FEV1 measurements, 4,906 European ancestry individuals with high FEV1 measurements NA Affymetrix [28509962] (imputed) 5 forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0004314 GCST008659 Genome-wide genotyping array 14656 2019-09-13 26423011 Wain LV 2015-09-27 Lancet Respir Med www.ncbi.nlm.nih.gov/pubmed/26423011 Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank. Lung function in never smokers (high FEV1 vs average FEV1) 4,902 European ancestry individuals with high FEV1 measurements, 9,827 European ancestry individuals with average FEV1 measurements NA Affymetrix [28509962] (imputed) 8 forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0004314 GCST008660 Genome-wide genotyping array 14731 2019-09-13 26423011 Wain LV 2015-09-27 Lancet Respir Med www.ncbi.nlm.nih.gov/pubmed/26423011 Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank. Lung function in heavy smokers (high FEV1 vs average FEV1) 4,906 European ancestry individuals with high FEV1 measurements, 9,803 European ancestry individuals with average FEV1 measurements NA Affymetrix [28509962] (imputed) 3 forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0004314 GCST008661 Genome-wide genotyping array 14711 2019-09-13 26423011 Wain LV 2015-09-27 Lancet Respir Med www.ncbi.nlm.nih.gov/pubmed/26423011 Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank. Lung function in never smokers (low FEV1 vs average FEV1) 9,745 European ancestry individuals with low FEV1 measurements, 9,827 European ancestry individuals with average FEV1 measurements NA Affymetrix [28509962] (imputed) 4 forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0004314 GCST008663 Genome-wide genotyping array 19574 2019-09-13 26423011 Wain LV 2015-09-27 Lancet Respir Med www.ncbi.nlm.nih.gov/pubmed/26423011 Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank. Lung function in heavy smokers (low FEV1 vs average FEV1) 9,748 European ancestry individuals with low FEV1 measurements, 9,803 European ancestry individuals with average FEV1 measurements NA Affymetrix [28509962] (imputed) 0 forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0004314 GCST008665 Genome-wide genotyping array 19553 2019-09-13 26423011 Wain LV 2015-09-27 Lancet Respir Med www.ncbi.nlm.nih.gov/pubmed/26423011 Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank. Smoking status (heavy vs never) 24,457 European ancestry heavy smokers, 24,474 European ancestry never smokers NA Affymetrix [28509962] (imputed) 13 smoking status measurement http://www.ebi.ac.uk/efo/EFO_0006527 GCST008667 Genome-wide genotyping array 48931 2019-09-13 26423011 Wain LV 2015-09-27 Lancet Respir Med www.ncbi.nlm.nih.gov/pubmed/26423011 Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank. Lung function (low FEV1 vs high FEV1) x smoking interaction 9,745 European ancestry never smokers with low FEV1 measurements, 4,902 European ancestry never smokers with high FEV1 measurements, 9,748 European ancestry heavy smokers with low FEV1 measurements, 4,906 European ancestry heavy smokers with high FEV1 measurements NA Affymetrix [28509962] (imputed) 15 smoking status measurement, forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0004314 GCST008666 Genome-wide genotyping array 29305 2019-09-13 26423011 Wain LV 2015-09-27 Lancet Respir Med www.ncbi.nlm.nih.gov/pubmed/26423011 Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank. Lung function (low FEV1 vs high FEV1) 19,493 European ancestry individuals with low FEV1 measurements, 9,808 European ancestry individuals with high FEV1 measurements NA Affymetrix [28509962] (imputed) 17 forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0004314 GCST008664 Genome-wide genotyping array 29303 2019-09-13 26423011 Wain LV 2015-09-27 Lancet Respir Med www.ncbi.nlm.nih.gov/pubmed/26423011 Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank. Lung function in never smokers (low FEV1 vs high FEV1) 9,745 European ancestry individuals with low FEV1 measurements, 4,902 European ancestry individuals with high FEV1 measurements NA Affymetrix [28509962] (imputed) 18 forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0004314 GCST008662 Genome-wide genotyping array 14649 2019-09-20 31396565 van der Lee SJ 2019-08-02 Commun Biol www.ncbi.nlm.nih.gov/pubmed/31396565 A genome-wide association study identifies genetic loci associated with specific lobar brain volumes. Occipital lobe volume 15,269 European ancestry individuals 8,789 European ancestry individuals Affymetrix, Illumina, Perlegen [NR] (imputed) 2 occipital lobe volume measurement http://www.ebi.ac.uk/efo/EFO_0010145 GCST008703 Genome-wide genotyping array 15269 2019-09-20 31396565 van der Lee SJ 2019-08-02 Commun Biol www.ncbi.nlm.nih.gov/pubmed/31396565 A genome-wide association study identifies genetic loci associated with specific lobar brain volumes. Parietal lobe volume 15,269 European ancestry individuals 8,789 European ancestry individuals Affymetrix, Illumina, Perlegen [NR] (imputed) 0 parietal lobe volume measurement http://www.ebi.ac.uk/efo/EFO_0010146 GCST008704 Genome-wide genotyping array 15269 2019-09-20 31396565 van der Lee SJ 2019-08-02 Commun Biol www.ncbi.nlm.nih.gov/pubmed/31396565 A genome-wide association study identifies genetic loci associated with specific lobar brain volumes. Temporal lobe volume 15,269 European ancestry individuals 8,789 European ancestry individuals Affymetrix, Illumina, Perlegen [NR] (imputed) 0 temporal lobe volume measurement http://www.ebi.ac.uk/efo/EFO_0010147 GCST008705 Genome-wide genotyping array 15269 2019-09-20 31396565 van der Lee SJ 2019-08-02 Commun Biol www.ncbi.nlm.nih.gov/pubmed/31396565 A genome-wide association study identifies genetic loci associated with specific lobar brain volumes. Occipital lobe volume 15,269 European ancestry individuals, 405 African American individuals, 211 Chinese ancestry individuals, 131 Malay ancestry individuals NA Affymetrix, Illumina, Perlegen [NR] (imputed) 4 occipital lobe volume measurement http://www.ebi.ac.uk/efo/EFO_0010145 GCST008707 Genome-wide genotyping array 16016 2019-09-20 31396565 van der Lee SJ 2019-08-02 Commun Biol www.ncbi.nlm.nih.gov/pubmed/31396565 A genome-wide association study identifies genetic loci associated with specific lobar brain volumes. Parietal lobe volume 15,269 European ancestry individuals, 405 African American individuals, 211 Chinese ancestry individuals, 131 Malay ancestry individuals NA Affymetrix, Illumina, Perlegen [NR] (imputed) 2 parietal lobe volume measurement http://www.ebi.ac.uk/efo/EFO_0010146 GCST008710 Genome-wide genotyping array 16016 2019-09-20 31396565 van der Lee SJ 2019-08-02 Commun Biol www.ncbi.nlm.nih.gov/pubmed/31396565 A genome-wide association study identifies genetic loci associated with specific lobar brain volumes. Temporal lobe volume 15,269 European ancestry individuals, 405 African American individuals, 211 Chinese ancestry individuals, 131 Malay ancestry individuals NA Affymetrix, Illumina, Perlegen [NR] (imputed) 1 temporal lobe volume measurement http://www.ebi.ac.uk/efo/EFO_0010147 GCST008711 Genome-wide genotyping array 16016 2019-09-20 31396565 van der Lee SJ 2019-08-02 Commun Biol www.ncbi.nlm.nih.gov/pubmed/31396565 A genome-wide association study identifies genetic loci associated with specific lobar brain volumes. Frontal lobe volume 15,269 European ancestry individuals 8,789 European ancestry individuals Affymetrix, Illumina, Perlegen [NR] (imputed) 0 frontal lobe volume measurement http://www.ebi.ac.uk/efo/EFO_0010144 GCST008715 Genome-wide genotyping array 15269 2019-09-20 31396565 van der Lee SJ 2019-08-02 Commun Biol www.ncbi.nlm.nih.gov/pubmed/31396565 A genome-wide association study identifies genetic loci associated with specific lobar brain volumes. Frontal lobe volume 15,269 European ancestry individuals, 405 African American individuals, 211 Chinese ancestry individuals, 131 Malay ancestry individuals NA Affymetrix, Illumina, Perlegen [NR] (imputed) 0 frontal lobe volume measurement http://www.ebi.ac.uk/efo/EFO_0010144 GCST008717 Genome-wide genotyping array 16016 2019-08-23 31434886 Luo Y 2019-08-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31434886 Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians. Early progression to active pulmonary tuberculosis in Mycobacterium tuberculosis-infected individuals 2,160 Peruvian cases, 1,820 Peruvian controls NA Affymetrix [7756401] (imputed) 1 Tuberculosis, susceptibility to Mycobacterium tuberculosis infection measurement http://www.orpha.net/ORDO/Orphanet_3389, http://www.ebi.ac.uk/efo/EFO_0008407 GCST008488 Genome-wide genotyping array 3980 2019-08-29 31315583 Lona-Durazo F 2019-07-17 BMC Genet www.ncbi.nlm.nih.gov/pubmed/31315583 Meta-analysis of GWA studies provides new insights on the genetic architecture of skin pigmentation in recently admixed populations. Skin pigmentation (conditioned on rs1426654 and rs35397) 1,047 Hispanic/Latin American individuals, 684 Cape Verdian individuals, 373 African American individuals NA Affymetrix, Illumina [at least 292549] (imputed) 79 skin pigmentation measurement http://www.ebi.ac.uk/efo/EFO_0007009 GCST008516 Genome-wide genotyping array 2104 2019-08-29 31315583 Lona-Durazo F 2019-07-17 BMC Genet www.ncbi.nlm.nih.gov/pubmed/31315583 Meta-analysis of GWA studies provides new insights on the genetic architecture of skin pigmentation in recently admixed populations. Skin pigmentation 762 Cuban ancestry individuals NA NR [292549] (imputed) 54 skin pigmentation measurement http://www.ebi.ac.uk/efo/EFO_0007009 GCST008518 Genome-wide genotyping array 762 2019-08-29 31315583 Lona-Durazo F 2019-07-17 BMC Genet www.ncbi.nlm.nih.gov/pubmed/31315583 Meta-analysis of GWA studies provides new insights on the genetic architecture of skin pigmentation in recently admixed populations. Skin pigmentation 1,047 Hispanic/Latin American individuals, 684 Cape Verdian individuals, 373 African American individuals East African ancestry individuals (See Crawford et. al, 2017) Affymetrix, Illumina [at least 292549] (imputed) 7 skin pigmentation measurement http://www.ebi.ac.uk/efo/EFO_0007009 GCST008519 Genome-wide genotyping array 2104 2019-03-07 30578418 Giri A 2018-12-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30578418 Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. Systolic blood pressure 365,998 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals 299,024 European ancestry individuals, 17,277 individuals Affymetrix [NR] (imputed) 340 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST007267 Genome-wide genotyping array 459777 2019-03-07 30578418 Giri A 2018-12-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30578418 Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. Diastolic blood pressure 365,998 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals 299,024 European ancestry individuals, 17,277 individuals Affymetrix [NR] (imputed) 80 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST007268 Genome-wide genotyping array 459777 2019-03-07 30578418 Giri A 2018-12-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30578418 Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. Pulse pressure 365,998 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals 299,024 European ancestry individuals, 17,277 individuals Affymetrix [NR] (imputed) 331 pulse pressure measurement http://www.ebi.ac.uk/efo/EFO_0005763 GCST007269 Genome-wide genotyping array 459777 2019-03-07 30578418 Giri A 2018-12-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30578418 Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. Systolic blood pressure 225,112 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals 445,360 individuals Affymetrix [NR] (imputed) 14 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST007270 Genome-wide genotyping array 318891 2019-03-07 30578418 Giri A 2018-12-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30578418 Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. Diastolic blood pressure 225,112 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals 445,360 individuals Affymetrix [NR] (imputed) 4 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST007271 Genome-wide genotyping array 318891 2019-03-07 30578418 Giri A 2018-12-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30578418 Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. Pulse pressure 225,112 European ancestry individuals, 63,490 African ancestry individuals, 22,802 Hispanic individuals, 4,792 Asian ancestry individuals, 2,695 Native American ancestry individuals 445,360 individuals Affymetrix [NR] (imputed) 45 pulse pressure measurement http://www.ebi.ac.uk/efo/EFO_0005763 GCST007272 Genome-wide genotyping array 318891 2020-07-14 32154731 Ripatti P 2020-03-10 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/32154731 Polygenic Hyperlipidemias and Coronary Artery Disease Risk. Low density lipoprotein cholesterol levels 324,708 British ancestry individuals NA Affymetrix [5701386] (imputed) 217 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST010204 Genome-wide genotyping array 324708 2020-07-09 32154731 Ripatti P 2020-03-10 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/32154731 Polygenic Hyperlipidemias and Coronary Artery Disease Risk. Triglyceride levels 324,694 British ancestry individuals NA Affymetrix [5701386] (imputed) 183 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST010173 Genome-wide genotyping array 324694 2019-02-01 30573740 Yap CX 2018-12-20 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30573740 Dissection of genetic variation and evidence for pleiotropy in male pattern baldness. Male-pattern baldness 205,327 European ancestry males NA NR [19129689] (imputed) 622 balding measurement http://www.ebi.ac.uk/efo/EFO_0007825 GCST007020 Genome-wide genotyping array 205327 2020-02-19 31636452 Satizabal CL 2019-10-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31636452 Genetic architecture of subcortical brain structures in 38,851 individuals. Nucleus accumbens volume 32,562 European ancestry individuals 341 South East and East Asian ancestry individuals, 85 African American individuals Affymetrix, Illumina [NR] (imputed) 9 nucleus accumbens volume http://www.ebi.ac.uk/efo/EFO_0006931 GCST009670 Genome-wide genotyping array 32562 2020-02-19 31636452 Satizabal CL 2019-10-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31636452 Genetic architecture of subcortical brain structures in 38,851 individuals. Amygdala volume 34,431 European ancestry individuals 341 South East and East Asian ancestry individuals, 769 African American individuals Affymetrix, Illumina [NR] (imputed) 1 amygdala volume http://www.ebi.ac.uk/efo/EFO_0006934 GCST009664 Genome-wide genotyping array 34431 2020-02-25 31636452 Satizabal CL 2019-10-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31636452 Genetic architecture of subcortical brain structures in 38,851 individuals. Brainstem volume 28,809 European ancestry individuals 341 South East and East Asian ancestry individuals, 85 African American individuals Affymetrix, Illumina [NR] (imputed) 17 brain stem volume measurement http://www.ebi.ac.uk/efo/EFO_0010605 GCST009697 Genome-wide genotyping array 28809 2020-02-19 31636452 Satizabal CL 2019-10-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31636452 Genetic architecture of subcortical brain structures in 38,851 individuals. Caudate nucleus volume 37,741 European ancestry individuals 341 South East and East Asian ancestry individuals, 769 African American individuals Affymetrix, Illumina [NR] (imputed) 17 caudate nucleus volume http://www.ebi.ac.uk/efo/EFO_0004830 GCST009666 Genome-wide genotyping array 37741 2020-02-19 31636452 Satizabal CL 2019-10-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31636452 Genetic architecture of subcortical brain structures in 38,851 individuals. Pallidum volume 34,413 European ancestry individuals 341 South East and East Asian ancestry individuals, 769 African American individuals Affymetrix, Illumina [NR] (imputed) 11 pallidum volume http://www.ebi.ac.uk/efo/EFO_0006933 GCST009667 Genome-wide genotyping array 34413 2020-02-19 31636452 Satizabal CL 2019-10-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31636452 Genetic architecture of subcortical brain structures in 38,851 individuals. Putamen volume 37,571 European ancestry individuals 341 South East and East Asian ancestry individuals, 769 African American individuals Affymetrix, Illumina [NR] (imputed) 16 putamen volume http://www.ebi.ac.uk/efo/EFO_0006932 GCST009668 Genome-wide genotyping array 37571 2020-02-19 31636452 Satizabal CL 2019-10-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31636452 Genetic architecture of subcortical brain structures in 38,851 individuals. Thalamus volume 34,464 European ancestry individuals 341 South East and East Asian ancestry individuals, 769 African American individuals Affymetrix, Illumina [NR] (imputed) 2 thalamus volume http://www.ebi.ac.uk/efo/EFO_0006935 GCST009669 Genome-wide genotyping array 34464 2020-02-17 31834638 Gloaguen E 2019-12-13 Ann Hum Genet www.ncbi.nlm.nih.gov/pubmed/31834638 "General regression model: A ""model-free"" association test for quantitative traits allowing to test for the underlying genetic model." Hemoglobin A1c levels 695 individuals NA Illumina [301183] 2 hemoglobin A1 measurement http://www.ebi.ac.uk/efo/EFO_0007629 GCST009641 Genome-wide genotyping array 695 2020-02-27 31170332 Zheng J 2019-08-02 J Bone Miner Res www.ncbi.nlm.nih.gov/pubmed/31170332 Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and Fractures. Serum sclerostin levels 10,584 European ancestry individuals NA NR [5245208] (imputed) 3 sclerostin measurement http://www.ebi.ac.uk/efo/EFO_0010606 GCST009708 Genome-wide genotyping array 10584 2021-01-06 29874175 Bihlmeyer NA 2018-01-01 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/29874175 ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals. QT interval 83,884 European ancestry individuals, 9,610 African American individuals, 1,382 Hispanic individuals, 750 East Asian ancestry individuals. NA Illumina [up to 209449] 29 QT interval http://www.ebi.ac.uk/efo/EFO_0004682 GCST010919 Exome genotyping array 95626 2021-01-06 29874175 Bihlmeyer NA 2018-01-01 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/29874175 ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals. JT interval up to 83,884 European ancestry individuals, up to 9,610 African American individuals, up to 1,382 Hispanic individuals, up to750 East Asian ancestry individuals. NA Illumina [up to 209449] 4 JT interval http://www.ebi.ac.uk/efo/EFO_0007885 GCST010918 Exome genotyping array 95626 2021-07-08 33393196 Soliai M 2021-01-03 Int Forum Allergy Rhinol www.ncbi.nlm.nih.gov/pubmed/33393196 Two-stage genome-wide association study of chronic rhinosinusitis and disease subphenotypes highlights mucosal immunity contributing to risk. Chronic rhinosinusitis 483 European ancestry cases, 2,057 European ancestry controls NA Illumina [4528849] (imputed) 6 chronic rhinosinusitis http://www.ebi.ac.uk/efo/EFO_1000024 GCST012015 Genome-wide genotyping array 2540 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Sortilin levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010173 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Lipoprotein lipase levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010149 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Serine/threonine-protein kinase 4 levels 1,095 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010175 Genome-wide sequencing [22x] 1095 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Tyrosine-protein kinase Mer levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010151 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Protein-glutamine gamma-glutamyltransferase 2 levels 1,291 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010177 Genome-wide sequencing [22x] 1291 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. NF-kappa-B essential modulator levels 1,298 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010154 Genome-wide sequencing [22x] 1298 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Thrombopoietin levels 1,300 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010179 Genome-wide sequencing [22x] 1300 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Proteinase-activated receptor 1 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010156 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Thrombomodulin levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010181 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Platelet-derived growth factor subunit B levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010158 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Tumor necrosis factor receptor superfamily member 11A levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010183 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Placenta growth factor levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010160 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Polymeric immunoglobulin receptor levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010161 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Prolargin levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010162 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. V-set and immunoglobulin domain-containing protein 2 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010187 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Prostasin levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010164 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. CD166 antigen levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010189 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Aminopeptidase N levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010190 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Tyrosine-protein kinase receptor UFO levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010191 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Azurocidin levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010192 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Bleomycin hydrolase levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010193 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Stem cell factor levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010169 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. C-C motif chemokine 15 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010195 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. SLAM family member 7 levels 1,299 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010171 Genome-wide sequencing [22x] 1299 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Superoxide dismutase [Mn],mitochondrial levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010172 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Leptin levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010148 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Spondin-2 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010174 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Macrophage receptor MARCO levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010150 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Tissue factor levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010176 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Matrix metalloproteinase-12 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010152 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Matrix metalloproteinase-7 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010153 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Thrombospondin-2 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010178 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Pappalysin-1 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010155 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Angiopoietin-1 receptor levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010180 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Poly [ADP-ribose] polymerase 1 levels 823 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010157 Genome-wide sequencing [22x] 823 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Tumor necrosis factor receptor superfamily member 10A levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010182 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Programmed cell death 1 ligand 2 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010159 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Tumor necrosis factor receptor superfamily member 13B levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010184 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. TNF-related apoptosis-inducing ligand receptor 2 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010185 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. vascular endothelial growth factor D levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010186 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Serine protease 27 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010163 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. XCL1 levels 1,280 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010188 Genome-wide sequencing [22x] 1280 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. P-selectin glycoprotein ligand 1 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010165 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Pentraxin-related protein PTX3 levels 1,292 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010166 Genome-wide sequencing [22x] 1292 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Receptor for advanced glycosylation end products levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010167 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Renin levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010168 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Caspase-3 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010194 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Serpin A12 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010170 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. C-C motif chemokine 16 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010196 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. C-C motif chemokine 24 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010197 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. C-type lectin domain family 5 member A levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010298 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. CXADR-like membrane protein levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010299 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Calsyntenin-2 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010300 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Clusterin-like protein 1 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010301 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Catechol O-methyltransferase levels 1,239 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010302 Genome-wide sequencing [22x] 1239 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Crk-like protein levels 1,105 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010303 Genome-wide sequencing [22x] 1105 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Pro-cathepsin H levels 1,278 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010304 Genome-wide sequencing [22x] 1278 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Cathepsin O levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010305 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Aromatic-L-amino-acid decarboxylase levels 180 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010306 Genome-wide sequencing [22x] 180 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Dipeptidyl peptidase 2 levels 1,290 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010307 Genome-wide sequencing [22x] 1290 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Gamma-enolase levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010308 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010309 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Ectonucleoside triphosphate diphosphohydrolase 5 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010310 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Protein FAM3C levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010311 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Fructose-1,6-bisphosphatase 1 levels 1,174 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010312 Genome-wide sequencing [22x] 1174 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Fc receptor-like protein 1 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010313 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Peptidyl-prolyl cis-trans isomerase FKBP4 levels 1,120 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010314 Genome-wide sequencing [22x] 1120 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Galanin peptide levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010315 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Glutaredoxin-1 levels 1,227 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010316 Genome-wide sequencing [22x] 1227 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. GRB2-related adapter protein 2 levels 923 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010317 Genome-wide sequencing [22x] 923 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Insulin-like growth factor-binding protein-like 1 levels 1,312 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010318 Genome-wide sequencing [22x] 1312 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Integrin beta-7 levels 1,211 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010319 Genome-wide sequencing [22x] 1211 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Kallikrein-10 levels 1,312 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010320 Genome-wide sequencing [22x] 1312 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Kynurenine-oxoglutarate transaminase 1 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010321 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Leukocyte immunoglobulin-like receptor subfamily A member 5 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010322 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Leucine-rich repeats and immunoglobulin-like domains protein 1 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010323 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Low-density lipoprotein receptor-related protein 11 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010324 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Multiple coagulation factor deficiency protein 2 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010325 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Meprin A subunit beta levels 1,200 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010326 Genome-wide sequencing [22x] 1200 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Meteorin-like protein levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010327 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. NAD kinase levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010328 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Nectin-2 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010329 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Nodal modulator 1 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010330 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Neural proliferation differentiation and control protein 1 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010331 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Neuronal pentraxin receptor levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010332 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 levels 1,308 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010333 Genome-wide sequencing [22x] 1308 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Paired immunoglobulin-like type 2 receptor beta levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010334 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Protein phosphatase inhibitor 2 levels 1,300 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010335 Genome-wide sequencing [22x] 1300 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Dihydropteridine reductase levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010336 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Regenerating islet-derived protein 4 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010337 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Eosinophil cationic protein levels 1,309 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010338 Genome-wide sequencing [22x] 1309 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Inactive tyrosine-protein kinase transmembrane receptor ROR1 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010339 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Reticulon-4 receptor levels 1,312 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010340 Genome-wide sequencing [22x] 1312 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Protein S100-A12 levels 1,100 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010341 Genome-wide sequencing [22x] 1100 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Syndecan-4 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010342 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Semaphorin-3F levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010343 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Serpin B6 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010344 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Serpin B8 levels 1,254 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010345 Genome-wide sequencing [22x] 1254 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Sialic acid-binding Ig-like lectin 7 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010346 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Synaptosomal-associated protein 23 levels 909 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010347 Genome-wide sequencing [22x] 909 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Tartrate-resistant acid phosphatase type 5 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010273 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Urokinase-type plasminogen activator levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010274 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Urokinase plasminogen activator surface receptor levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010275 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. vWF levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010276 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Lysophosphatidic acid phosphatase type 6 levels 1,311 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010277 Genome-wide sequencing [22x] 1311 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Adhesion G protein-coupled receptor E2 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010278 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Adhesion G-protein coupled receptor G2 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010279 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Retinal dehydrogenase 1 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010280 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Angiopoietin-2 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010281 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Angiopoietin-related protein 1 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010282 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Angiopoietin-related protein 7 levels 1,306 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010283 Genome-wide sequencing [22x] 1306 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. DNA-(apurinic or apyrimidinic site) lyase levels 1,187 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010284 Genome-wide sequencing [22x] 1187 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Amyloid-like protein 1 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010285 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Arginase-1 levels 1,072 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010286 Genome-wide sequencing [22x] 1072 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Large proline-rich protein BAG6 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010287 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Carbonic anhydrase 13 levels 1,248 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010288 Genome-wide sequencing [22x] 1248 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Soluble calcium-activated nucleotidase 1 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010289 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Coiled-coil domain-containing protein 80 levels 1,309 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010290 Genome-wide sequencing [22x] 1309 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Sialomucin core protein 24 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010291 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. T-cell surface glycoprotein CD1c levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010292 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. CD2-associated protein levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010293 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. B-cell antigen receptor complex-associated protein beta chain levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010294 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Cadherin-2 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010295 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Cadherin-related family member 5 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010296 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Chordin-like protein 2 levels 1,279 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010297 Genome-wide sequencing [22x] 1279 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Platelet endothelial cell adhesion molecule levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010248 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Peptidoglycan recognition protein 1 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010249 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Elafin levels 1,322 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010250 Genome-wide sequencing [22x] 1322 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Perlecan levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010251 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Paraoxonase activity 1,322 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010252 Genome-wide sequencing [22x] 1322 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Myeloblastin levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010253 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Pulmonary surfactant-associated protein D levels 1,316 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010254 Genome-wide sequencing [22x] 1316 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Retinoic acid receptor responder protein 2 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010255 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Resistin levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010256 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Secretoglobin family 3A member 2 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010257 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. E-selectin levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010258 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. P-selectin levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010259 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Tyrosine-protein phosphatase non-receptor type substrate 1 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010260 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Spondin-1 levels 1,314 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010261 Genome-wide sequencing [22x] 1314 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. ST2 protein levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010262 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Tissue factor pathway inhibitor levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010263 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Metalloproteinase inhibitor 4 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010264 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Trem-like transcript 2 protein levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010265 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Tumor necrosis factor receptor 1 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010266 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Tumor necrosis factor receptor 2 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010267 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Tumor necrosis factor receptor superfamily member 10C levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010268 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Tumor necrosis factor receptor superfamily member 14 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010269 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Tumor necrosis factor ligand superfamily member 13B levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010270 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Tissue-type plasminogen activator levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010271 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Transferrin receptor protein 1 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010272 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Scavenger receptor cysteine-rich type 1 protein M130 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010198 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Complement component C1q receptor levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010199 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Cadherin-5 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010200 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Chitinase-3-like protein 1 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010201 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Chitotriosidase-1 levels 1,184 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010202 Genome-wide sequencing [22x] 1184 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Contactin-1 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010203 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Collagen alpha-1 (I) chain levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010204 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Carboxypeptidase A1 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010205 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Carboxypeptidase B levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010206 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Cystatin-B levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010207 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Cathepsin D levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010208 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Cathepsin Z levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010209 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. C-X-C motif chemokine 16 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010210 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Protein delta homolog 1 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010211 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Epidermal growth factor levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010212 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. epithelial cell adhesion molecule levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010213 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Ephrin type-B receptor 4 levels 1,322 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010214 Genome-wide sequencing [22x] 1322 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Fatty acid-binding protein, adipocyte levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010215 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Tumor necrosis factor receptor superfamily member 6 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010216 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Galectin-3 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010217 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Galectin-4 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010218 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Granulins levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010219 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Intercellular adhesion molecule 2 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010220 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Insulin-like growth factor-binding protein 1 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010221 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Insulin-like growth factor-binding protein 2 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010222 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Interleukin-1 receptor type 2 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010227 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Interleukin-2 receptor subunit alpha levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010228 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Interleukin-6 receptor subunit alpha levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010229 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Integrin beta-2 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010230 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Junctional adhesion molecule A levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010231 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Kallikrein-6 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010232 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Low-density lipoprotein receptor levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010233 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Lymphotoxin-beta receptor levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010234 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Myoglobin levels 1,322 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010235 Genome-wide sequencing [22x] 1322 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Monocyte chemoattractant protein-1 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010236 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Matrix extracellular phosphoglycoprotein levels 974 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010237 Genome-wide sequencing [22x] 974 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Matrix metalloproteinase-2 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010238 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Matrix metalloproteinase-3 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010239 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Matrix metalloproteinase-9 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010240 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Myeloperoxidase levels 1,322 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010241 Genome-wide sequencing [22x] 1322 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Neurogenic locus notch homolog protein 3 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010242 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Osteoprotegerin levels 1,243 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010243 Genome-wide sequencing [22x] 1243 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Osteopontin levels 1,322 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010244 Genome-wide sequencing [22x] 1322 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Plasminogen activator inhibitor-1 (PAI-1) levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010245 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Proprotein convertase subtilisin/kexin type 9 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010246 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Platelet-derived growth factor subunit A levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010247 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Insulin-like growth factor-binding protein 7 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010223 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Interleukin-17 receptor A levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010224 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Interleukin-18-binding protein levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010225 Genome-wide sequencing [22x] 1323 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Interleukin-1 receptor type 1 levels 1,323 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010226 Genome-wide sequencing [22x] 1323 2021-08-02 33106475 Li QS 2020-10-26 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/33106475 Genome-wide association studies of antidepressant class response and treatment-resistant depression. Response to serotonin-norepinephrine reuptake inhibitors (responders vs non-responders) 4,030 European ancestry responders, 3,049 European ancestry non-responders NA Illumina [at least 560000] (imputed) 26 response to serotonin-norephinephrine reuptake inhibitor http://www.ebi.ac.uk/efo/EFO_0006325 GCST012159 Genome-wide genotyping array 7079 2021-08-02 33106475 Li QS 2020-10-26 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/33106475 Genome-wide association studies of antidepressant class response and treatment-resistant depression. Response to norepinephrine-dopamine reuptake inhibitors (responders vs non-responders) 3,971 European ancestry responders, 3,512 European ancestry non-responders NA Illumina [at least 560000] (imputed) 19 response to norepinephrine-dopamine reuptake inhibitor http://www.ebi.ac.uk/efo/EFO_0007870 GCST012158 Genome-wide genotyping array 7483 2021-08-02 33106475 Li QS 2020-10-26 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/33106475 Genome-wide association studies of antidepressant class response and treatment-resistant depression. Response to antidepressants (non-treatment-resistant vs treatment-resistant depression) 21,649 European ancestry individuals with non-treatment-resistant depression, 3,857 European ancestry individuals with treatment-resistant depression NA Illumina [at least 560000] (imputed) 27 response to antidepressant http://purl.obolibrary.org/obo/GO_0036276 GCST012157 Genome-wide genotyping array 25506 2021-08-02 33106475 Li QS 2020-10-26 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/33106475 Genome-wide association studies of antidepressant class response and treatment-resistant depression. Response to SSRI (responders vs non-responders) 13,130 European ancestry responders, 6,610 European ancestry non-responders NA Illumina [at least 560000] (imputed) 15 response to selective serotonin reuptake inhibitor http://www.ebi.ac.uk/efo/EFO_0005658 GCST012160 Genome-wide genotyping array 19740 2021-02-23 33407418 Jonsson A 2021-01-06 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/33407418 Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test. Glucagon levels in response to oral glucose tolerance test (decremental area under the curve for 0-30 minutes) 553 European ancestry individuals, 1,346 individuals NA Illumina [NR] (imputed) 10 glucagon measurement, glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0008463, http://www.ebi.ac.uk/efo/EFO_0004307 GCST011140 Genome-wide genotyping array 1899 2021-02-23 33407418 Jonsson A 2021-01-06 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/33407418 Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test. Glucagon levels in response to oral glucose tolerance test (decremental area under the curve for 0-120 minutes) 553 European ancestry individuals, 1,346 individuals NA Illumina [NR] (imputed) 11 glucagon measurement, glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0008463, http://www.ebi.ac.uk/efo/EFO_0004307 GCST011139 Genome-wide genotyping array 1899 2021-02-23 33407418 Jonsson A 2021-01-06 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/33407418 Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test. Glucagon levels in response to oral glucose tolerance test (fasting) 553 European ancestry individuals, 1,346 individuals NA Illumina [NR] (imputed) 23 glucagon measurement, glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0008463, http://www.ebi.ac.uk/efo/EFO_0004307 GCST011138 Genome-wide genotyping array 1899 2021-02-23 33407418 Jonsson A 2021-01-06 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/33407418 Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test. Glucagon levels in response to oral glucose tolerance test (30 minutes) 553 European ancestry individuals, 1,346 individuals NA Illumina [NR] (imputed) 11 glucagon measurement, glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0008463, http://www.ebi.ac.uk/efo/EFO_0004307 GCST011137 Genome-wide genotyping array 1899 2021-02-23 33407418 Jonsson A 2021-01-06 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/33407418 Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test. Glucagon levels in response to oral glucose tolerance test (120 minutes) 553 European ancestry individuals, 1,346 individuals NA Illumina [NR] (imputed) 29 glucagon measurement, glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0008463, http://www.ebi.ac.uk/efo/EFO_0004307 GCST011136 Genome-wide genotyping array 1899 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Sclerostin levels 1,312 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010348 Genome-wide sequencing [22x] 1312 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Scavenger receptor cysteine-rich domain-containing group B protein levels 1,272 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010349 Genome-wide sequencing [22x] 1272 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Sulfatase-modifying factor 2 levels 1,312 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010350 Genome-wide sequencing [22x] 1312 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Trefoil factor 2 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010351 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Thimet oligopeptidase levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010352 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Thyrotropin subunit beta levels 1,285 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010353 Genome-wide sequencing [22x] 1285 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Thioredoxin domain-containing protein 5 levels 1,309 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010354 Genome-wide sequencing [22x] 1309 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Thymidine phosphorylase levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010355 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Tyrosine-protein kinase receptor TYRO3 levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010356 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Ubiquitin carboxyl-terminal hydrolase 8 levels 1,138 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010357 Genome-wide sequencing [22x] 1138 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Versican core protein levels 1,313 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010358 Genome-wide sequencing [22x] 1313 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Angiotensin-converting enzyme 2 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010102 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. A disintegrin and metalloproteinase with thrombospondin motifs 13 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010103 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Agouti-related protein levels 1,300 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010104 Genome-wide sequencing [22x] 1300 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Protein AMBP levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010105 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Angiopoietin-1 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010106 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Bone morphogenetic protein 6 levels 1,214 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010107 Genome-wide sequencing [22x] 1214 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Brother of CDO levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010108 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Carbonic anhydrase 5A,mitochondrial levels 1,263 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010109 Genome-wide sequencing [22x] 1263 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. C-C motif chemokine 17 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010110 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. C-C motif chemokine 3 levels 1,288 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010111 Genome-wide sequencing [22x] 1288 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. T-cell surface glycoprotein CD4 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010112 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. CD40 ligand levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010113 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. SLAM family member 5 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010114 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Carcinoembryonic antigenrelated cell adhesion molecule 8 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010115 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Chymotrypsin C levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010116 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Cathepsin L1 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010117 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. C-X-C motif chemokine 1 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010118 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Decorin levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010119 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. 2,4-dienoyl-CoA reductase,mitochondrial levels 1,296 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010120 Genome-wide sequencing [22x] 1296 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Dickkopf-related protein 1 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010121 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Fatty acid-binding protein,intestinal levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010122 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Fibroblast growth factor 21 levels 1,298 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010123 Genome-wide sequencing [22x] 1298 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Fibroblast growth factor 23 levels 1,286 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010124 Genome-wide sequencing [22x] 1286 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Follistatin levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010125 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Galectin-9 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010126 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Growth/differentiation factor 2 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010127 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Growth hormone levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010128 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Gastric intrinsic factor levels 1,299 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010129 Genome-wide sequencing [22x] 1299 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Lactoylglutathione lyase levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010130 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Gastrotropin levels 1,047 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010131 Genome-wide sequencing [22x] 1047 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Hydroxyacid oxidase 1 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010132 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Proheparin-binding EGF-like growth factor levels 1,300 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010133 Genome-wide sequencing [22x] 1300 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Heme oxygenase 1 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010134 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Osteoclast-associated immunoglobulin-like receptor levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010135 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Heat shock 27 kDa protein levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010136 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Alpha-L-iduronidase levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010137 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Low affinity immunoglobulin gamma Fc region receptor II-b levels 1,295 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010138 Genome-wide sequencing [22x] 1295 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Pro-interleukin-16 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010139 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Interleukin-17D levels 1,299 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010140 Genome-wide sequencing [22x] 1299 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Interleukin-18 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010141 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Interleukin-1-receptor antagonist levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010142 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Interleukin-1 receptor-like 2 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010143 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Interleukin-27 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010144 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Interleukin-4 receptor subunit alpha levels 1,292 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010145 Genome-wide sequencing [22x] 1292 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Interleukin-6 levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010146 Genome-wide sequencing [22x] 1301 2021-01-20 33303764 Gilly A 2020-12-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33303764 Whole-genome sequencing analysis of the cardiometabolic proteome. Kidney Injury Molecule levels 1,301 European ancestry individuals NA Illumina [13419876] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90010147 Genome-wide sequencing [22x] 1301 2019-07-09 30662464 Yang C 2018-12-18 J Oncol www.ncbi.nlm.nih.gov/pubmed/30662464 Clinical Implication and the Hereditary Factors of NM23 in Hepatocellular Carcinoma Based on Bioinformatics Analysis and Genome-Wide Association Study. Nucleoside diphosphate kinase A levels in hepatocellular carcinoma 408 East Asian ancestry individuals NA Illumina [21529] 0 nucleoside diphosphate kinase A measurement http://www.ebi.ac.uk/efo/EFO_0009947 GCST008104 Genome-wide genotyping array 408 2020-06-17 32327693 Oskarsson GR 2020-04-23 Commun Biol www.ncbi.nlm.nih.gov/pubmed/32327693 Predicted loss and gain of function mutations in ACO1 are associated with erythropoiesis. Hemoglobin levels 684,122 European ancestry individuals NA Affymetrix, Illumina [43000000] (imputed) 362 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST010083 Genome-wide genotyping array, Genome-wide sequencing 684122 2021-07-27 33402679 Lagou V 2021-01-05 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33402679 Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Fasting glucose 151,188 European ancestry individuals NA Affymetrix, Illumina [8700000] (imputed) 41 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST012078 Genome-wide genotyping array, Targeted genotyping array 151188 2021-07-27 33402679 Lagou V 2021-01-05 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33402679 Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Fasting glucose 67,506 European ancestry men NA Affymetrix, Illumina [8700000] (imputed) 25 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST012077 Genome-wide genotyping array, Targeted genotyping array 67506 2021-07-27 33402679 Lagou V 2021-01-05 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33402679 Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Fasting glucose 73,089 European ancestry women NA Affymetrix, Illumina [8700000] (imputed) 27 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST012076 Genome-wide genotyping array, Targeted genotyping array 73089 2021-07-27 33402679 Lagou V 2021-01-05 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33402679 Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Fasting insulin 105,056 European ancestry individuals NA Affymetrix, Illumina [8700000] (imputed) 17 fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004466 GCST012079 Genome-wide genotyping array, Targeted genotyping array 105056 2021-07-27 33402679 Lagou V 2021-01-05 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33402679 Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Fasting insulin 47,806 European ancestry men NA Affymetrix, Illumina [8700000] (imputed) 8 fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004466 GCST012075 Genome-wide genotyping array, Targeted genotyping array 47806 2021-07-27 33402679 Lagou V 2021-01-05 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33402679 Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Fasting insulin 50,404 European ancestry women NA Affymetrix, Illumina [8700000] (imputed) 7 fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004466 GCST012074 Genome-wide genotyping array, Targeted genotyping array 50404 2020-02-07 31761296 Hernandez Cordero AI 2019-11-21 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31761296 Genome-wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and STC2. Appendicular lean mass 85,750 European ancestry middle-aged adult individuals NA Affymetrix [21375087] (imputed) 182 appendicular lean mass http://www.ebi.ac.uk/efo/EFO_0004980 GCST009576 Genome-wide genotyping array 85750 2020-02-07 31761296 Hernandez Cordero AI 2019-11-21 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31761296 Genome-wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and STC2. Appendicular lean mass 181,862 European ancestry elderly individuals NA Affymetrix [17914406] (imputed) 391 appendicular lean mass http://www.ebi.ac.uk/efo/EFO_0004980 GCST009577 Genome-wide genotyping array 181862 2019-03-25 30659259 Imaizumi A 2019-01-18 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30659259 Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population. Plasma free amino acid levels (adjusted for twenty other PFAAs) 1,338 Japanese ancestry individuals NA Illumina [1288202] (imputed) 38 amino acid measurement http://www.ebi.ac.uk/efo/EFO_0005134 GCST007382 Genome-wide genotyping array 1338 2019-03-25 30659259 Imaizumi A 2019-01-18 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30659259 Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population. Plasma free amino acid levels (adjusted for one other PFAA) 1,338 Japanese ancestry individuals NA Illumina [1288202] (imputed) 82 amino acid measurement http://www.ebi.ac.uk/efo/EFO_0005134 GCST007383 Genome-wide genotyping array 1338 2019-03-25 30659259 Imaizumi A 2019-01-18 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30659259 Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population. Plasma free proline levels 1,338 Japanese ancestry individuals 665 Japanese ancestry individuals Illumina [up to 1288202] (imputed) 1 proline measurement http://www.ebi.ac.uk/efo/EFO_0009773 GCST007384 Genome-wide genotyping array 1338 2019-03-25 30659259 Imaizumi A 2019-01-18 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30659259 Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population. Plasma free asparagine levels 1,338 Japanese ancestry individuals 665 Japanese ancestry individuals Illumina [up to 1288202] (imputed) 1 asparagine measurement http://www.ebi.ac.uk/efo/EFO_0009766 GCST007386 Genome-wide genotyping array 1338 2019-03-25 30659259 Imaizumi A 2019-01-18 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30659259 Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population. Plasma free amino acid levels 1,338 Japanese ancestry individuals NA Illumina [1288202] (imputed) 34 amino acid measurement http://www.ebi.ac.uk/efo/EFO_0005134 GCST007385 Genome-wide genotyping array 1338 2019-03-28 30664655 Adhikari K 2019-01-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30664655 A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia. Skin pigmentation 6,236 Latin American individuals NA Illumina [8896142] (imputed) 14 skin pigmentation measurement http://www.ebi.ac.uk/efo/EFO_0007009 GCST007452 Genome-wide genotyping array 6236 2019-03-28 30664655 Adhikari K 2019-01-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30664655 A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia. Eye color (saturation) 6,236 Latin American individuals NA Illumina [8896142] (imputed) 10 eye colour measurement http://www.ebi.ac.uk/efo/EFO_0009764 GCST007457 Genome-wide genotyping array 6236 2019-03-28 30664655 Adhikari K 2019-01-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30664655 A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia. Eye color 6,236 Latin American individuals NA Illumina [8896142] (imputed) 9 eye colour measurement http://www.ebi.ac.uk/efo/EFO_0009764 GCST007453 Genome-wide genotyping array 6236 2019-03-28 30664655 Adhikari K 2019-01-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30664655 A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia. Hair color 6,236 Latin American individuals NA Illumina [8896142] (imputed) 7 hair colour measurement http://www.ebi.ac.uk/efo/EFO_0007822 GCST007454 Genome-wide genotyping array 6236 2019-03-28 30664655 Adhikari K 2019-01-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30664655 A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia. Eye color (brightness) 6,236 Latin American individuals NA Illumina [8896142] (imputed) 11 eye colour measurement http://www.ebi.ac.uk/efo/EFO_0009764 GCST007455 Genome-wide genotyping array 6236 2019-03-28 30664655 Adhikari K 2019-01-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30664655 A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia. Eye color (hue) 6,236 Latin American individuals NA Illumina [8896142] (imputed) 3 eye colour measurement http://www.ebi.ac.uk/efo/EFO_0009764 GCST007456 Genome-wide genotyping array 6236 2019-03-28 30664655 Adhikari K 2019-01-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30664655 A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia. Skin, hair and eye pigmentation (multivariate analysis) 6,236 Latin American individuals NA Illumina [181139] (imputed) 11 hair colour measurement, eye colour measurement, skin pigmentation measurement http://www.ebi.ac.uk/efo/EFO_0007822, http://www.ebi.ac.uk/efo/EFO_0009764, http://www.ebi.ac.uk/efo/EFO_0007009 GCST007451 Genome-wide genotyping array 6236 2019-12-05 30715261 Brouwer WP 2019-02-02 Clin Infect Dis www.ncbi.nlm.nih.gov/pubmed/30715261 Genome Wide Association Study Identifies Genetic Variants Associated With Early And Sustained Response To (Peg)Interferon In Chronic Hepatitis B Patients: The GIANT-B Study. Response to (pegylated) interferon in HBeAg-negative hepatitis B 161 Asian, European, African and other ancestry cases, 253 Asian, European, African and other ancestry controls NA Illumina [8102086] (imputed) 4 response to interferon http://www.ebi.ac.uk/efo/EFO_0007859 GCST009172 Genome-wide genotyping array 414 2019-12-05 30715261 Brouwer WP 2019-02-02 Clin Infect Dis www.ncbi.nlm.nih.gov/pubmed/30715261 Genome Wide Association Study Identifies Genetic Variants Associated With Early And Sustained Response To (Peg)Interferon In Chronic Hepatitis B Patients: The GIANT-B Study. Response to (pegylated) interferon in HBeAG-positive hepatitis B 121 Asian, European, African and other ancestry cases, 388 Asian, European, African and other ancestry controls NA Illumina [8102086] (imputed) 2 response to interferon http://www.ebi.ac.uk/efo/EFO_0007859 GCST009173 Genome-wide genotyping array 509 2019-12-05 30715261 Brouwer WP 2019-02-02 Clin Infect Dis www.ncbi.nlm.nih.gov/pubmed/30715261 Genome Wide Association Study Identifies Genetic Variants Associated With Early And Sustained Response To (Peg)Interferon In Chronic Hepatitis B Patients: The GIANT-B Study. Response to (pegylated) interferon in chronic hepatitis B 282 Asian, European, African and other ancestry cases, 641 Asian, European, African and other ancestry controls NA Illumina [8102086] (imputed) 3 response to interferon http://www.ebi.ac.uk/efo/EFO_0007859 GCST009174 Genome-wide genotyping array 923 2020-07-08 32066663 Niarchou M 2020-02-03 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32066663 Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits. Meat-related diet 154,123 European ancestry men, 181,453 European ancestry women NA Affymetrix [25921788] (imputed) 40 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST010143 Genome-wide genotyping array 335576 2020-07-08 32066663 Niarchou M 2020-02-03 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32066663 Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits. Pork consumption 335,576 European ancestry individuals NA Affymetrix [25921788] (imputed) 52 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST010140 Genome-wide genotyping array 335576 2020-07-08 32066663 Niarchou M 2020-02-03 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32066663 Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits. Poultry consumption 335,576 European ancestry individuals NA Affymetrix [25921788] (imputed) 2 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST010139 Genome-wide genotyping array 335576 2020-07-08 32066663 Niarchou M 2020-02-03 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32066663 Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits. Raw vegetable consumption 335,576 European ancestry individuals NA Affymetrix [25921788] (imputed) 17 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST010138 Genome-wide genotyping array 335576 2020-07-08 32066663 Niarchou M 2020-02-03 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32066663 Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits. Cooked vegetable consumption 335,576 European ancestry individuals NA Affymetrix [25921788] (imputed) 9 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST010137 Genome-wide genotyping array 335576 2020-07-08 32066663 Niarchou M 2020-02-03 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32066663 Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits. Fruit consumption 335,576 European ancestry individuals NA Affymetrix [25921788] (imputed) 53 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST010136 Genome-wide genotyping array 335576 2020-07-08 32066663 Niarchou M 2020-02-03 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32066663 Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits. Oily fish consumption 335,576 European ancestry individuals NA Affymetrix [25921788] (imputed) 52 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST010135 Genome-wide genotyping array 335576 2020-07-08 32066663 Niarchou M 2020-02-03 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32066663 Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits. Non-oily fish consumption 335,576 European ancestry individuals NA Affymetrix [25921788] (imputed) 7 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST010134 Genome-wide genotyping array 335576 2020-07-08 32066663 Niarchou M 2020-02-03 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32066663 Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits. Lamb consumption 335,576 European ancestry individuals NA Affymetrix [25921788] (imputed) 18 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST010133 Genome-wide genotyping array 335576 2020-07-08 32066663 Niarchou M 2020-02-03 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32066663 Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits. Processed meat consumption 335,576 European ancestry individuals NA Affymetrix [25921788] (imputed) 15 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST010132 Genome-wide genotyping array 335576 2020-07-08 32066663 Niarchou M 2020-02-03 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32066663 Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits. Fish- and plant-related diet 154,123 European ancestry men, 181,453 European ancestry women NA Affymetrix [25921788] (imputed) 94 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST010142 Genome-wide genotyping array 335576 2020-07-08 32066663 Niarchou M 2020-02-03 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32066663 Genome-wide association study of dietary intake in the UK biobank study and its associations with schizophrenia and other traits. Beef consumption 335,576 European ancestry individuals NA Affymetrix [25921788] (imputed) 7 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST010141 Genome-wide genotyping array 335576 2020-03-05 31959995 Schlosser P 2020-01-20 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31959995 Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans. Urinary metabolite modules (eigenmetabolites) in chronic kidney disease 1,221 cases 406 cases Illumina [7750367] (imputed) 46 urinary metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005116 GCST009735 Genome-wide genotyping array 1221 2020-03-03 31959995 Schlosser P 2020-01-20 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31959995 Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans. Urinary metabolite levels in chronic kidney disease 1,221 cases 406 cases Illumina [7750367] (imputed) 240 urinary metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005116 GCST009733 Genome-wide genotyping array 1221 2020-07-21 32235003 Arbeev KG 2020-04-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/32235003 Genetics of physiological dysregulation: findings from the long life family study using joint models. Physiological dysregulation (Mahalanobis distance) 4,608 European ancestry individuals NA Illumina [1464300] 3 hematological measurement, pulmonary function measurement, blood pressure, grip strength measurement, lipoprotein measurement, vital capacity http://www.ebi.ac.uk/efo/EFO_0004503, http://www.ebi.ac.uk/efo/EFO_0003892, http://www.ebi.ac.uk/efo/EFO_0004325, http://www.ebi.ac.uk/efo/EFO_0006941, http://www.ebi.ac.uk/efo/EFO_0004732, http://www.ebi.ac.uk/efo/EFO_0004312 GCST010279 Genome-wide genotyping array 4608 2020-07-21 32235003 Arbeev KG 2020-04-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/32235003 Genetics of physiological dysregulation: findings from the long life family study using joint models. Hand grip strength (Mahalanobis distance) 4,608 European ancestry individuals NA Illumina [1464300] 8 grip strength measurement http://www.ebi.ac.uk/efo/EFO_0006941 GCST010278 Genome-wide genotyping array 4608 2020-04-30 31768069 Jiang L 2019-11-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31768069 A resource-efficient tool for mixed model association analysis of large-scale data. Multiple traits (2,148) 46,191 European ancestry individuals NA NR [152369] 0 complex trait http://www.ebi.ac.uk/efo/EFO_0010578 GCST009923 Exome-wide sequencing 46191 2020-04-30 31768069 Jiang L 2019-11-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31768069 A resource-efficient tool for mixed model association analysis of large-scale data. Multiple traits (2,173) 456,422 European ancestry individuals NA NR [8531416] (imputed) 0 complex trait http://www.ebi.ac.uk/efo/EFO_0010578 GCST009924 Genome-wide genotyping array 456422 2020-01-27 31660654 Bandres-Ciga S 2019-10-29 Mov Disord www.ncbi.nlm.nih.gov/pubmed/31660654 The Genetic Architecture of Parkinson Disease in Spain: Characterizing Population-Specific Risk, Differential Haplotype Structures, and Providing Etiologic Insight. Parkinson's disease (age of onset) 3,997 Spanish ancestry individuals NA Illumina [9911207] (imputed) 2 Parkinson's disease, age at onset http://www.ebi.ac.uk/efo/EFO_0002508, http://www.ebi.ac.uk/efo/EFO_0004847 GCST009513 Genome-wide genotyping array 3997 2020-01-27 31660654 Bandres-Ciga S 2019-10-29 Mov Disord www.ncbi.nlm.nih.gov/pubmed/31660654 The Genetic Architecture of Parkinson Disease in Spain: Characterizing Population-Specific Risk, Differential Haplotype Structures, and Providing Etiologic Insight. Parkinson's disease 4,639 Spanish ancestry cases, 2,949 Spanish ancestry controls NA Illumina [9911207] (imputed) 7 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST009512 Genome-wide genotyping array 7588 2020-01-08 30297969 Mahajan A 2018-10-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30297969 Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. Type 2 diabetes (adjusted for BMI) 50,409 European ancestry cases, 523,897 European ancestry controls NA Affymetrix, Illumina [~ 27000000] (imputed) 17 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST009380 Genome-wide genotyping array 574306 2020-01-08 30297969 Mahajan A 2018-10-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30297969 Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. Type 2 diabetes 74,124 European ancestry cases, 824,006 European ancestry controls NA Affymetrix, Illumina [~ 27000000] (imputed) 383 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST009379 Genome-wide genotyping array 898130 2019-12-19 31701892 Nalls MA 2019-12-01 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/31701892 Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies. Parkinson's disease or first degree relation to individual with Parkinson's disease 15,056 European ancestry cases, 18,618 European ancestry proxy cases, 449,056 European ancestry controls 22,632 European ancestry cases, 968,735 European ancestry controls NR [7784415] (imputed) 107 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST009325 Genome-wide genotyping array 482730 2019-12-19 31701892 Nalls MA 2019-12-01 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/31701892 Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies. Parkinson's disease 15,056 European ancestry cases, 12,637 European ancestry controls 22,632 European ancestry cases, 968,735 European ancestry controls NR [7784415] (imputed) 0 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST009324 Genome-wide genotyping array 27693 2019-12-10 31688885 Genetics of Glaucoma in People of African Descent (GGLAD) Consortium 2019-11-01 JAMA www.ncbi.nlm.nih.gov/pubmed/31688885 Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry. Glaucoma (primary open-angle) 694 African American cases, 1,590 Sub-Saharan African cases, 596 African American controls, 1,485 Sub-Saharan African controls 6,937 African ancestry cases, 14,917 African ancestry controls Illumina [6734161] (imputed) 1 open-angle glaucoma http://www.ebi.ac.uk/efo/EFO_0004190 GCST009245 Genome-wide genotyping array 4365 2020-01-29 31712720 Forstner AJ 2019-11-11 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/31712720 Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression. Panic disorder 2,147 European ancestry cases, 7,760 European ancestry controls 2,408 European ancestry cases, 228,470 European ancestry controls Illumina [8757275] (imputed) 5 panic disorder http://www.ebi.ac.uk/efo/EFO_0004262 GCST009525 Genome-wide genotyping array 9907 2020-07-14 31729902 Penney KL 2019-11-15 J Urol www.ncbi.nlm.nih.gov/pubmed/31729902 Genome-wide Association Study for Urinary and Fecal Incontinence in Women. Urinary incontinence 6,120 European ancestry female cases, 4,811 European ancestry female controls NA Affymetrix, Illumina [1410640] (imputed) 0 Urinary incontinence http://purl.obolibrary.org/obo/HP_0000020 GCST010205 Genome-wide genotyping array 10931 2020-05-01 31729902 Penney KL 2019-11-15 J Urol www.ncbi.nlm.nih.gov/pubmed/31729902 Genome-wide Association Study for Urinary and Fecal Incontinence in Women. Stress urinary incontinence 1,809 European ancestry female cases, 4,811 European ancestry female controls NA Affymetrix, Illumina [1410640] (imputed) 1 Stress urinary incontinence http://purl.obolibrary.org/obo/HP_0010992 GCST009927 Genome-wide genotyping array 6620 2020-07-14 31729902 Penney KL 2019-11-15 J Urol www.ncbi.nlm.nih.gov/pubmed/31729902 Genome-wide Association Study for Urinary and Fecal Incontinence in Women. Urgency urinary incontinence 1,942 European ancestry female cases, 4,811 European ancestry female controls NA Affymetrix, Illumina [1410640] (imputed) 0 urgency urinary incontinence http://www.ebi.ac.uk/efo/EFO_0006865 GCST009926 Genome-wide genotyping array 6753 2020-05-01 31729902 Penney KL 2019-11-15 J Urol www.ncbi.nlm.nih.gov/pubmed/31729902 Genome-wide Association Study for Urinary and Fecal Incontinence in Women. Stress urinary incontinence and urgency urinary incontinence 2,036 European ancestry female cases, 4,811 European ancestry female controls NA Affymetrix, Illumina [1410640] (imputed) 0 Urinary incontinence http://purl.obolibrary.org/obo/HP_0000020 GCST009928 Genome-wide genotyping array 6847 2020-05-01 31729902 Penney KL 2019-11-15 J Urol www.ncbi.nlm.nih.gov/pubmed/31729902 Genome-wide Association Study for Urinary and Fecal Incontinence in Women. Fecal incontinence 4,247 European ancestry female cases, 11,634 European ancestry female controls NA Affymetrix, Illumina [1410640] (imputed) 2 fecal incontinence http://www.ebi.ac.uk/efo/EFO_0009523 GCST009925 Genome-wide genotyping array 15881 2020-02-06 31749835 Sangurdekar D 2019-11-04 Front Genet www.ncbi.nlm.nih.gov/pubmed/31749835 Genetic Study of Severe Prolonged Lymphopenia in Multiple Sclerosis Patients Treated With Dimethyl Fumarate. Severe prolonged lymphopenia in dimethyl fumarate-treated relapsing-remitting multiple sclerosis 42 European ancestry cases, 1,052 European ancestry controls NA Illumina [1016025] 3 response to dimethyl fumarate, lymphopenia http://www.ebi.ac.uk/efo/EFO_0010577, http://purl.obolibrary.org/obo/MONDO_0003783 GCST009546 Genome-wide genotyping array 1094 2020-02-06 31749835 Sangurdekar D 2019-11-04 Front Genet www.ncbi.nlm.nih.gov/pubmed/31749835 Genetic Study of Severe Prolonged Lymphopenia in Multiple Sclerosis Patients Treated With Dimethyl Fumarate. Moderate or severe prolonged lymphopenia in dimethyl fumarate-treated relapsing-remitting multiple sclerosis 206 European ancestry cases, 1,052 European ancestry controls NA Illumina [1016018] 6 response to dimethyl fumarate, lymphopenia http://www.ebi.ac.uk/efo/EFO_0010577, http://purl.obolibrary.org/obo/MONDO_0003783 GCST009545 Genome-wide genotyping array 1258 2020-01-29 31707593 Kulminski AM 2019-11-09 Geroscience www.ncbi.nlm.nih.gov/pubmed/31707593 Polygenic risk score for disability and insights into disability-related molecular mechanisms. Disability (impaired activities of daily living) 7,544 European ancestry cases, 4,619 European ancestry controls 5,006 European ancestry cases, 6,899 European ancestry controls Illumina [NR] 4 activities of daily living score measurement http://www.ebi.ac.uk/efo/EFO_0008451 GCST009526 Genome-wide genotyping array 12163 2020-02-17 31767839 Vijayakrishnan J 2019-11-25 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31767839 Identification of four novel associations for B-cell acute lymphoblastic leukaemia risk. B-cell acute lymphoblastic leukaemia 5,321 European ancestry cases, 16,666 European ancestry controls 2,237 cases, 3,461 controls Affymetrix, Illumina [~ 6118121] (imputed) 10 B-cell acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000094 GCST009638 Genome-wide genotyping array 21987 2020-02-17 31767839 Vijayakrishnan J 2019-11-25 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31767839 Identification of four novel associations for B-cell acute lymphoblastic leukaemia risk. B-cell acute lymphoblastic leukaemia (high-hyperdiploidy) 1,369 European ancestry cases, 16,666 European ancestry controls 422 cases, 3,461 controls Affymetrix, Illumina [~ 6118121] (imputed) 1 B-cell acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000094 GCST009637 Genome-wide genotyping array 18035 2020-02-17 31767839 Vijayakrishnan J 2019-11-25 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31767839 Identification of four novel associations for B-cell acute lymphoblastic leukaemia risk. B-cell acute lymphoblastic leukaemia (ETV6-RUNX1 positive) 936 European ancestry cases, 16,666 European ancestry controls 365 cases, 3,461 controls Affymetrix, Illumina [~ 6118121] (imputed) 1 B-cell acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000094 GCST009636 Genome-wide genotyping array 17602 2020-01-30 31766143 Ortega-Azorin C 2019-11-13 Nutrients www.ncbi.nlm.nih.gov/pubmed/31766143 Candidate Gene and Genome-Wide Association Studies for Circulating Leptin Levels Reveal Population and Sex-Specific Associations in High Cardiovascular Risk Mediterranean Subjects. Circulating leptin levels in high cardiovascular risk 351 Spanish mediterranean ancestry men, 615 Spanish mediterranean ancestry women NA Illumina [628376] 25 leptin measurement http://www.ebi.ac.uk/efo/EFO_0005000 GCST009532 Genome-wide genotyping array 966 2020-01-30 31766143 Ortega-Azorin C 2019-11-13 Nutrients www.ncbi.nlm.nih.gov/pubmed/31766143 Candidate Gene and Genome-Wide Association Studies for Circulating Leptin Levels Reveal Population and Sex-Specific Associations in High Cardiovascular Risk Mediterranean Subjects. Circulating leptin levels x sex interaction in high cardiovascular risk 351 Spanish mediterranean ancestry men, 615 Spanish mediterranean ancestry women NA Illumina [628376] 5 leptin measurement, sex interaction measurement http://www.ebi.ac.uk/efo/EFO_0005000, http://www.ebi.ac.uk/efo/EFO_0008343 GCST009533 Genome-wide genotyping array 966 2020-01-22 31763980 Xiong Z 2019-11-25 Elife www.ncbi.nlm.nih.gov/pubmed/31763980 Novel genetic loci affecting facial shape variation in humans. Facial morphology 10,115 European ancestry individuals NA Illumina [7029494] (imputed) 41 facial morphology measurement http://www.ebi.ac.uk/efo/EFO_0007841 GCST009464 Genome-wide genotyping array 10115 2020-02-13 31760383 Guo Y 2019-11-23 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/31760383 Genome-wide association study of hippocampal atrophy rate in non-demented elders. Hippocampal atrophy rate 602 European ancestry elderly individuals NA Illumina [695203] 3 hippocampal atrophy http://www.ebi.ac.uk/efo/EFO_0005039 GCST009608 Genome-wide genotyping array 602 2020-02-06 25147954 Enroth S 2014-08-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25147954 Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. Interleukin-6 receptor subunit alpha levels up to 653 individuals up to 317 individuals Illumina [4840842] (imputed) 1 interleukin 6 receptor subunit alpha measurement http://www.ebi.ac.uk/efo/EFO_0008187 GCST009561 Exome genotyping array [Exome array] 653 2020-02-06 25147954 Enroth S 2014-08-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25147954 Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. C-X-C motif chemokine 10 levels up to 653 individuals up to 317 individuals Illumina [4840842] (imputed) 1 C-X-C motif chemokine 10 measurement http://www.ebi.ac.uk/efo/EFO_0008056 GCST009562 Exome genotyping array [Exome array] 653 2020-02-06 25147954 Enroth S 2014-08-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25147954 Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. CCL24 levels up to 653 individuals up to 317 individuals Illumina [4840842] (imputed) 1 CCL24 measurement http://www.ebi.ac.uk/efo/EFO_0009418 GCST009563 Exome genotyping array [Exome array] 653 2020-02-06 25147954 Enroth S 2014-08-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25147954 Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. MHC class I polypeptide-related sequence A levels up to 653 individuals up to 317 individuals Illumina [4840842] (imputed) 1 MHC class I polypeptide-related sequence A measurement http://www.ebi.ac.uk/efo/EFO_0008233 GCST009564 Exome genotyping array [Exome array] 653 2020-02-07 25147954 Enroth S 2014-08-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25147954 Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. CD40 ligand levels up to 653 individuals up to 317 individuals Illumina [4840842] (imputed) 1 CD40 ligand measurement http://www.ebi.ac.uk/efo/EFO_0004790 GCST009565 Exome genotyping array [Exome array] 653 2020-02-07 25147954 Enroth S 2014-08-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25147954 Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. CXCL5 levels up to 653 individuals up to 317 individuals Illumina [4840842] (imputed) 2 CXCL5 measurement http://www.ebi.ac.uk/efo/EFO_0009422 GCST009566 Exome genotyping array [Exome array] 653 2020-02-07 25147954 Enroth S 2014-08-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25147954 Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. kallikrein-11 levels up to 653 individuals up to 317 individuals Illumina [4840842] (imputed) 1 kallikrein-11 measurement http://www.ebi.ac.uk/efo/EFO_0010573 GCST009567 Exome genotyping array [Exome array] 653 2020-02-07 25147954 Enroth S 2014-08-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25147954 Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. epithelial cell adhesion molecule levels up to 653 individuals up to 317 individuals Illumina [4840842] (imputed) 2 epithelial cell adhesion molecule measurement http://www.ebi.ac.uk/efo/EFO_0010574 GCST009568 Exome genotyping array [Exome array] 653 2020-02-07 25147954 Enroth S 2014-08-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25147954 Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. interleukin 17 receptor B levels up to 653 individuals up to 317 individuals Illumina [4840842] (imputed) 1 interleukin 17 receptor B measurement http://www.ebi.ac.uk/efo/EFO_0008176 GCST009569 Exome genotyping array [Exome array] 653 2020-02-07 25147954 Enroth S 2014-08-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25147954 Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. interleukin 12 receptor subunit beta-1 levels up to 653 individuals up to 317 individuals Illumina [4840842] (imputed) 1 interleukin 12 receptor subunit beta-1 measurement http://www.ebi.ac.uk/efo/EFO_0008170 GCST009570 Exome genotyping array [Exome array] 653 2020-02-07 25147954 Enroth S 2014-08-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25147954 Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. vascular endothelial growth factor D levels up to 653 individuals up to 317 individuals Illumina [4840842] (imputed) 2 vascular endothelial growth factor D measurement http://www.ebi.ac.uk/efo/EFO_0010575 GCST009571 Exome genotyping array [Exome array] 653 2020-02-07 25147954 Enroth S 2014-08-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25147954 Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. E-selectin levels up to 653 individuals up to 317 individuals Illumina [4840842] (imputed) 1 e-selectin measurement http://www.ebi.ac.uk/efo/EFO_0004575 GCST009572 Exome genotyping array [Exome array] 653 2020-02-07 25147954 Enroth S 2014-08-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25147954 Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. melanoma-derived growth regulatory protein levels up to 653 individuals up to 317 individuals Illumina [4840842] (imputed) 2 melanoma-derived growth regulatory protein measurement http://www.ebi.ac.uk/efo/EFO_0008229 GCST009573 Exome genotyping array [Exome array] 653 2020-02-06 25147954 Enroth S 2014-08-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25147954 Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. CCL19 levels up to 653 individuals up to 317 individuals Illumina [4840842] (imputed) 1 CCL19 measurement http://www.ebi.ac.uk/efo/EFO_0009415 GCST009558 Exome genotyping array [Exome array] 653 2020-02-14 31806883 de Las Fuentes L 2019-12-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/31806883 Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry. LDL cholesterol levels x loop diuretics use interaction 2,117 European ancestry exposed individuals, 30,715 European ancestry unexposed individuals, 784 African American and African ancestry exposed individuals, 5,218 African American and African ancestry unexposed individuals NA Affymetrix, Illumina [NR] (imputed) 4 response to diuretic, low density lipoprotein cholesterol measurement http://purl.obolibrary.org/obo/GO_0036270, http://www.ebi.ac.uk/efo/EFO_0004611 GCST009614 Genome-wide genotyping array 38834 2020-02-14 31806883 de Las Fuentes L 2019-12-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/31806883 Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry. Triglyceride levels x loop diuretics use interaction 2,117 European ancestry exposed individuals, 30,715 European ancestry unexposed individuals, 784 African American and African ancestry exposed individuals, 5,218 African American and African ancestry unexposed individuals NA Affymetrix, Illumina [NR] (imputed) 22 triglyceride measurement, response to diuretic http://www.ebi.ac.uk/efo/EFO_0004530, http://purl.obolibrary.org/obo/GO_0036270 GCST009615 Genome-wide genotyping array 38834 2020-02-14 31806883 de Las Fuentes L 2019-12-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/31806883 Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry. HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction 6,878 European ancestry exposed individuals, 30,715 European ancestry unexposed individuals, 3,923 African American and African ancestry exposed individuals, 5,218 African American and African ancestry unexposed individuals NA Affymetrix, Illumina [NR] (imputed) 6 response to diuretic, high density lipoprotein cholesterol measurement http://purl.obolibrary.org/obo/GO_0036270, http://www.ebi.ac.uk/efo/EFO_0004612 GCST009616 Genome-wide genotyping array 46734 2020-02-14 31806883 de Las Fuentes L 2019-12-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/31806883 Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry. LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction 6,878 European ancestry exposed individuals, 30,715 European ancestry unexposed individuals, 3,923 African American and African ancestry exposed individuals, 5,218 African American and African ancestry unexposed individuals NA Affymetrix, Illumina [NR] (imputed) 2 response to diuretic, low density lipoprotein cholesterol measurement http://purl.obolibrary.org/obo/GO_0036270, http://www.ebi.ac.uk/efo/EFO_0004611 GCST009617 Genome-wide genotyping array 46734 2020-02-14 31806883 de Las Fuentes L 2019-12-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/31806883 Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry. Triglyceride levels x thiazide or thiazide-like diuretics use interaction 6,878 European ancestry exposed individuals, 30,715 European ancestry unexposed individuals, 3,923 African American and African ancestry exposed individuals, 5,218 African American and African ancestry unexposed individuals NA Affymetrix, Illumina [NR] (imputed) 3 triglyceride measurement, response to diuretic http://www.ebi.ac.uk/efo/EFO_0004530, http://purl.obolibrary.org/obo/GO_0036270 GCST009612 Genome-wide genotyping array 46734 2020-02-14 31806883 de Las Fuentes L 2019-12-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/31806883 Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry. HDL cholesterol levels x loop diuretics use interaction 2,117 European ancestry exposed individuals, 30,715 European ancestry unexposed individuals, 784 African American and African ancestry exposed individuals, 5,218 African American and African ancestry unexposed individuals NA Affymetrix, Illumina [NR] (imputed) 4 response to diuretic, high density lipoprotein cholesterol measurement http://purl.obolibrary.org/obo/GO_0036270, http://www.ebi.ac.uk/efo/EFO_0004612 GCST009613 Genome-wide genotyping array 38834 2020-07-21 32341051 Wang X 2020-04-01 BMJ Open Diabetes Res Care www.ncbi.nlm.nih.gov/pubmed/32341051 Shared genetic architecture and casual relationship between leptin levels and type 2 diabetes: large-scale cross-trait meta-analysis and Mendelian randomization analysis. Circulating leptin levels or fasting insulin levels 254,263 individuals NA NR [NR] 1 leptin measurement, fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0005000, http://www.ebi.ac.uk/efo/EFO_0004466 GCST010271 Genome-wide genotyping array 254263 2020-07-21 32341051 Wang X 2020-04-01 BMJ Open Diabetes Res Care www.ncbi.nlm.nih.gov/pubmed/32341051 Shared genetic architecture and casual relationship between leptin levels and type 2 diabetes: large-scale cross-trait meta-analysis and Mendelian randomization analysis. Circulating leptin levels or HOMA-B 254,263 individuals NA NR [NR] 1 leptin measurement, HOMA-B http://www.ebi.ac.uk/efo/EFO_0005000, http://www.ebi.ac.uk/efo/EFO_0004469 GCST010270 Genome-wide genotyping array 254263 2020-07-21 32341051 Wang X 2020-04-01 BMJ Open Diabetes Res Care www.ncbi.nlm.nih.gov/pubmed/32341051 Shared genetic architecture and casual relationship between leptin levels and type 2 diabetes: large-scale cross-trait meta-analysis and Mendelian randomization analysis. Circulating leptin levels or HOMA-IR 254,263 individuals NA NR [NR] 1 leptin measurement, HOMA-IR http://www.ebi.ac.uk/efo/EFO_0005000, http://www.ebi.ac.uk/efo/EFO_0004501 GCST010269 Genome-wide genotyping array 254263 2020-07-21 32341051 Wang X 2020-04-01 BMJ Open Diabetes Res Care www.ncbi.nlm.nih.gov/pubmed/32341051 Shared genetic architecture and casual relationship between leptin levels and type 2 diabetes: large-scale cross-trait meta-analysis and Mendelian randomization analysis. Circulating leptin levels or type 2 diabetes 254,263 individuals NA NR [NR] 12 leptin measurement, type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0005000, http://www.ebi.ac.uk/efo/EFO_0001360 GCST010272 Genome-wide genotyping array 254263 2019-05-10 30610197 Smeland OB 2019-01-04 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30610197 Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence. Bipolar disorder or intelligence (pleiotropy) 20,352 European ancestry bipolar disorder cases, 31,358 European ancestry controls, 269,867 individuals NA NR [9295119] (imputed) 0 intelligence, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0004337, http://www.ebi.ac.uk/efo/EFO_0000289 GCST007781 Genome-wide genotyping array 321577 2019-05-10 30610197 Smeland OB 2019-01-04 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30610197 Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence. Schizophrenia or intelligence (pleiotropy) 35,476 European and East Asian ancestry schizophrenia cases, 46,839 European and East Asian ancestry controls, 269,867 individuals NA NR [9295119] (imputed) 0 schizophrenia, intelligence http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0004337 GCST007782 Genome-wide genotyping array 352182 2020-01-30 31752434 Costa-Urrutia P 2019-11-19 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/31752434 Genome-Wide Association Study of Body Mass Index and Body Fat in Mexican-Mestizo Children. Childhood body mass index 828 Mexican-Mestizo ancestry individuals NA Affymetrix [~ 2500000] (imputed) 3 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST009530 Genome-wide genotyping array 828 2020-01-30 31752434 Costa-Urrutia P 2019-11-19 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/31752434 Genome-Wide Association Study of Body Mass Index and Body Fat in Mexican-Mestizo Children. Body fat percentage 828 Mexican-Mestizo ancestry children NA Affymetrix [~ 2500000] (imputed) 11 body fat percentage http://www.ebi.ac.uk/efo/EFO_0007800 GCST009531 Genome-wide genotyping array 828 2020-01-07 31755958 Blauwendraat C 2019-11-22 Brain www.ncbi.nlm.nih.gov/pubmed/31755958 Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia. Parkinson's disease in GBA mutation carriers 1,588 European ancestry cases, 7,584 European ancestry controls up to 1,194 European ancestry cases, up to 13,901 European ancestry controls Illumina [NR] (imputed) 2 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST009373 Genome-wide genotyping array 9172 2020-01-07 31755958 Blauwendraat C 2019-11-22 Brain www.ncbi.nlm.nih.gov/pubmed/31755958 Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia. Parkinson's disease in GBA mutation carriers (age at onset) 1,353 European ancestry cases NA Illumina [NR] (imputed) 0 Parkinson's disease, age at onset http://www.ebi.ac.uk/efo/EFO_0002508, http://www.ebi.ac.uk/efo/EFO_0004847 GCST009374 Genome-wide genotyping array 1353 2020-07-24 31991592 Coltell O 2020-01-24 Nutrients www.ncbi.nlm.nih.gov/pubmed/31991592 Genome-Wide Association Study for Serum Omega-3 and Omega-6 Polyunsaturated Fatty Acids: Exploratory Analysis of the Sex-Specific Effects and Dietary Modulation in Mediterranean Subjects with Metabolic Syndrome. Serum total polyunsaturated fatty acid concentration in metabolic syndrome 426 Mediterranean individuals NA Illumina [621723] 3 polyunsaturated fatty acid measurement http://www.ebi.ac.uk/efo/EFO_0010733 GCST010319 Genome-wide genotyping array 426 2020-07-24 31991592 Coltell O 2020-01-24 Nutrients www.ncbi.nlm.nih.gov/pubmed/31991592 Genome-Wide Association Study for Serum Omega-3 and Omega-6 Polyunsaturated Fatty Acids: Exploratory Analysis of the Sex-Specific Effects and Dietary Modulation in Mediterranean Subjects with Metabolic Syndrome. Serum omega-3 polyunsaturated fatty acid concentration in metabolic syndrome 426 Mediterranean individuals NA Illumina [621723] 10 omega-3 polyunsaturated fatty acid measurement http://www.ebi.ac.uk/efo/EFO_0010119 GCST010318 Genome-wide genotyping array 426 2020-07-24 31991592 Coltell O 2020-01-24 Nutrients www.ncbi.nlm.nih.gov/pubmed/31991592 Genome-Wide Association Study for Serum Omega-3 and Omega-6 Polyunsaturated Fatty Acids: Exploratory Analysis of the Sex-Specific Effects and Dietary Modulation in Mediterranean Subjects with Metabolic Syndrome. Serum omega-6 polyunsaturated fatty acid concentration in metabolic syndrome 426 Mediterranean individuals NA Illumina [621723] 4 omega-6 polyunsaturated fatty acid measurement http://www.ebi.ac.uk/efo/EFO_0005680 GCST010317 Genome-wide genotyping array 426 2020-07-24 31991592 Coltell O 2020-01-24 Nutrients www.ncbi.nlm.nih.gov/pubmed/31991592 Genome-Wide Association Study for Serum Omega-3 and Omega-6 Polyunsaturated Fatty Acids: Exploratory Analysis of the Sex-Specific Effects and Dietary Modulation in Mediterranean Subjects with Metabolic Syndrome. Serum docosahexaenoic fatty acid concentration in metabolic syndrome 426 Mediterranean individuals NA Illumina [621723] 11 docosahexaenoic acid measurement http://www.ebi.ac.uk/efo/EFO_0007761 GCST010316 Genome-wide genotyping array 426 2020-07-24 31991592 Coltell O 2020-01-24 Nutrients www.ncbi.nlm.nih.gov/pubmed/31991592 Genome-Wide Association Study for Serum Omega-3 and Omega-6 Polyunsaturated Fatty Acids: Exploratory Analysis of the Sex-Specific Effects and Dietary Modulation in Mediterranean Subjects with Metabolic Syndrome. Serum linoleic acid concentration in metabolic syndrome 426 Mediterranean individuals NA Illumina [621723] 6 linoleic acid measurement http://www.ebi.ac.uk/efo/EFO_0006807 GCST010315 Genome-wide genotyping array 426 2020-07-24 31991592 Coltell O 2020-01-24 Nutrients www.ncbi.nlm.nih.gov/pubmed/31991592 Genome-Wide Association Study for Serum Omega-3 and Omega-6 Polyunsaturated Fatty Acids: Exploratory Analysis of the Sex-Specific Effects and Dietary Modulation in Mediterranean Subjects with Metabolic Syndrome. Serum omega-6 to omega-3 polyunsaturated fatty acid ratio in metabolic syndrome 426 Mediterranean individuals NA Illumina [621723] 8 omega-6:omega-3 polyunsaturated fatty acid ratio http://www.ebi.ac.uk/efo/EFO_0010732 GCST010314 Genome-wide genotyping array 426 2020-07-24 31991592 Coltell O 2020-01-24 Nutrients www.ncbi.nlm.nih.gov/pubmed/31991592 Genome-Wide Association Study for Serum Omega-3 and Omega-6 Polyunsaturated Fatty Acids: Exploratory Analysis of the Sex-Specific Effects and Dietary Modulation in Mediterranean Subjects with Metabolic Syndrome. Serum polyunsaturated fatty acid concentration x sex interaction in metabolic syndrome 239 Mediterranean women, 187 Mediterranean men NA Illumina [621723] 10 polyunsaturated fatty acid measurement, sex interaction measurement http://www.ebi.ac.uk/efo/EFO_0010733, http://www.ebi.ac.uk/efo/EFO_0008343 GCST010313 Genome-wide genotyping array 426 2020-07-24 31991592 Coltell O 2020-01-24 Nutrients www.ncbi.nlm.nih.gov/pubmed/31991592 Genome-Wide Association Study for Serum Omega-3 and Omega-6 Polyunsaturated Fatty Acids: Exploratory Analysis of the Sex-Specific Effects and Dietary Modulation in Mediterranean Subjects with Metabolic Syndrome. Serum polyunsaturated fatty acid concentration x Mediterranean diet adherence interaction in metabolic syndrome 248 Mediterranean individuals with low adherence to Mediterranean diet, 178 Mediterranean individuals with high adherence to Mediterranean diet NA Illumina [621723] 19 polyunsaturated fatty acid measurement, diet measurement http://www.ebi.ac.uk/efo/EFO_0010733, http://www.ebi.ac.uk/efo/EFO_0008111 GCST010312 Genome-wide genotyping array 426 2020-03-04 32004448 Savage SA 2020-01-30 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32004448 Genome-wide Association Study Identifies HLA-DPB1 as a Significant Risk Factor for Severe Aplastic Anemia. Severe aplastic anemia 359 European ancestry cases, 1,396 European ancestry controls 175 European ancestry cases, 1,059 European ancestry controls Illumina [688067] 8 severe aplastic anemia http://www.ebi.ac.uk/efo/EFO_0006927 GCST009734 Genome-wide genotyping array 1755 2020-07-08 32041948 Sarin KY 2020-02-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32041948 Genome-wide meta-analysis identifies eight new susceptibility loci for cutaneous squamous cell carcinoma. Cutaneous squamous cell carcinoma 19,149 European ancestry cases, 680,049 European ancestry controls NA NR [13607369] (imputed) 26 cutaneous squamous cell carcinoma http://www.ebi.ac.uk/efo/EFO_1001927 GCST010148 Genome-wide genotyping array 699198 2020-07-09 32047095 Traglia M 2020-02-11 Genetics www.ncbi.nlm.nih.gov/pubmed/32047095 Genetic Contributions to Maternal and Neonatal Vitamin D Levels. Midgestational total 25-hydroxyvitamin D levels (maternal genetic effect) 269 European ancestry individuals, 323 Hispanic individuals, 115 East Asian ancestry individuals, 23 African American individuals, 23 South Asian ancestry individuals, 23 individuals NA Affymetrix [629686] 3 vitamin D measurement http://www.ebi.ac.uk/efo/EFO_0004631 GCST010171 Genome-wide genotyping array 776 2020-07-09 32047095 Traglia M 2020-02-11 Genetics www.ncbi.nlm.nih.gov/pubmed/32047095 Genetic Contributions to Maternal and Neonatal Vitamin D Levels. Neonatal total 25-hydroxyvitamin D levels (maternal genetic effect) 269 European ancestry individuals, 323 Hispanic individuals, 115 East Asian ancestry individuals, 23 African American individuals, 23 South Asian ancestry individuals, 23 individuals NA Affymetrix [629686] 7 vitamin D measurement, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0004631, http://www.ebi.ac.uk/efo/EFO_0005939 GCST010170 Genome-wide genotyping array 776 2020-07-09 32047095 Traglia M 2020-02-11 Genetics www.ncbi.nlm.nih.gov/pubmed/32047095 Genetic Contributions to Maternal and Neonatal Vitamin D Levels. Midgestational total 25-hydroxyvitamin D levels (fetal genetic effect) 269 European ancestry individuals, 323 Hispanic individuals, 115 East Asian ancestry individuals, 23 African American individuals, 23 South Asian ancestry individuals, 23 individuals NA Affymetrix [622716] 3 fetal genotype effect measurement, vitamin D measurement http://www.ebi.ac.uk/efo/EFO_0007959, http://www.ebi.ac.uk/efo/EFO_0004631 GCST010169 Genome-wide genotyping array 776 2020-07-09 32047095 Traglia M 2020-02-11 Genetics www.ncbi.nlm.nih.gov/pubmed/32047095 Genetic Contributions to Maternal and Neonatal Vitamin D Levels. Neonatal total 25-hydroxyvitamin D levels (fetal genetic effect) 269 European ancestry individuals, 323 Hispanic individuals, 115 East Asian ancestry individuals, 23 African American individuals, 23 South Asian ancestry individuals, 23 individuals NA Affymetrix [622716] 2 vitamin D measurement http://www.ebi.ac.uk/efo/EFO_0004631 GCST010168 Genome-wide genotyping array 776 2021-04-29 32048322 Kim Y 2020-02-11 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/32048322 Genome-wide interaction study of single-nucleotide polymorphisms and alcohol consumption on blood pressure: The Ansan and Ansung study of the Korean Genome and Epidemiology Study (KoGES). Blood pressure x alcohol consumption interaction 6,176 Korean ancestry individuals 18,708 Korean ancestry individuals Affymetrix [5908513] (imputed) 0 diastolic blood pressure, systolic blood pressure, alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0007878 GCST011571 Genome-wide genotyping array 6176 2018-11-09 29781551 Guo X 2018-05-21 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/29781551 A univariate perspective of multivariate genome-wide association analysis. Axial length 1,055 individuals NA NR [500025] 1 axial length measurement http://www.ebi.ac.uk/efo/EFO_0005318 GCST006541 Genome-wide genotyping array 1055 2018-11-09 29781551 Guo X 2018-05-21 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/29781551 A univariate perspective of multivariate genome-wide association analysis. Spherical error 1,055 individuals NA NR [500025] 0 refractive error measurement http://www.ebi.ac.uk/efo/EFO_0007814 GCST006539 Genome-wide genotyping array 1055 2019-01-10 29781551 Guo X 2018-05-21 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/29781551 A univariate perspective of multivariate genome-wide association analysis. Axial length or spherical error (univariate decomposition analysis) 1,055 individuals NA NR [500025] 5 axial length measurement, refractive error measurement http://www.ebi.ac.uk/efo/EFO_0005318, http://www.ebi.ac.uk/efo/EFO_0007814 GCST006864 Genome-wide genotyping array 1055 2020-04-16 31969989 Oni-Orisan A 2020-01-16 NPJ Genom Med www.ncbi.nlm.nih.gov/pubmed/31969989 The impact of adjusting for baseline in pharmacogenomic genome-wide association studies of quantitative change. Response to statins (LDL cholesterol percent change) 28,616 European ancestry individuals, 1,205 African ancestry individuals, 2,350 East Asian ancestry individuals, 2,703 Hispanic/Latino individuals NA Affymetrix [13250765] (imputed) 4 response to statin, LDL cholesterol change measurement http://purl.obolibrary.org/obo/GO_0036273, http://www.ebi.ac.uk/efo/EFO_0007804 GCST009821 Genome-wide genotyping array 34874 2020-03-09 31969989 Oni-Orisan A 2020-01-16 NPJ Genom Med www.ncbi.nlm.nih.gov/pubmed/31969989 The impact of adjusting for baseline in pharmacogenomic genome-wide association studies of quantitative change. Low density lipoprotein cholesterol levels 28,616 European ancestry individuals, 1,205 African ancestry individuals, 2,350 East Asian ancestry individuals, 2,703 Hispanic/Latino individuals NA Affymetrix [13250765] (imputed) 4 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST009757 Genome-wide genotyping array 34874 2020-07-27 31969989 Oni-Orisan A 2020-01-16 NPJ Genom Med www.ncbi.nlm.nih.gov/pubmed/31969989 The impact of adjusting for baseline in pharmacogenomic genome-wide association studies of quantitative change. Low density lipoprotein cholesterol levels (on statin treatment) 28,616 European ancestry individuals, 1,205 African ancestry individuals, 2,350 East Asian ancestry individuals, 2,703 Hispanic/Latino individuals NA Affymetrix [13250765] (imputed) 8 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST010337 Genome-wide genotyping array 34874 2020-07-27 31969989 Oni-Orisan A 2020-01-16 NPJ Genom Med www.ncbi.nlm.nih.gov/pubmed/31969989 The impact of adjusting for baseline in pharmacogenomic genome-wide association studies of quantitative change. Response to statins (LDL cholesterol change) 28,616 European ancestry individuals, 1,205 African ancestry individuals, 2,350 East Asian ancestry individuals, 2,703 Hispanic/Latino individuals NA Affymetrix [13250765] (imputed) 6 response to statin, LDL cholesterol change measurement http://purl.obolibrary.org/obo/GO_0036273, http://www.ebi.ac.uk/efo/EFO_0007804 GCST010338 Genome-wide genotyping array 34874 2020-04-16 31488892 Masuda T 2019-09-05 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31488892 GWAS of five gynecologic diseases and cross-trait analysis in Japanese. Uterine fibroids 5,236 Japanese ancestry cases, 39,556 Japanese ancestry controls NA Illumina [7645193] (imputed) 41 uterine fibroid http://www.ebi.ac.uk/efo/EFO_0000731 GCST009834 Genome-wide genotyping array 44792 2020-04-16 31488892 Masuda T 2019-09-05 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31488892 GWAS of five gynecologic diseases and cross-trait analysis in Japanese. Uterine fibroids (MTAG) 5,236 Japanese ancestry cases, 39,556 Japanese ancestry controls NA Illumina [7645193] (imputed) 30 uterine fibroid http://www.ebi.ac.uk/efo/EFO_0000731 GCST009833 Genome-wide genotyping array 44792 2020-04-16 31488892 Masuda T 2019-09-05 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31488892 GWAS of five gynecologic diseases and cross-trait analysis in Japanese. Endometriosis 645 Japanese ancestry cases, 39,556 Japanese ancestry controls NA Illumina [7645193] (imputed) 31 endometriosis http://www.ebi.ac.uk/efo/EFO_0001065 GCST009832 Genome-wide genotyping array 40201 2020-04-16 31488892 Masuda T 2019-09-05 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31488892 GWAS of five gynecologic diseases and cross-trait analysis in Japanese. Endometriosis (MTAG) 645 Japanese ancestry cases, 39,556 Japanese ancestry controls NA Illumina [7645193] (imputed) 15 endometriosis http://www.ebi.ac.uk/efo/EFO_0001065 GCST009831 Genome-wide genotyping array 40201 2020-04-16 31488892 Masuda T 2019-09-05 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31488892 GWAS of five gynecologic diseases and cross-trait analysis in Japanese. Ovarian cancer 647 Japanese ancestry cases, 39,556 Japanese ancestry controls NA Illumina [7645193] (imputed) 37 ovarian carcinoma http://www.ebi.ac.uk/efo/EFO_0001075 GCST009830 Genome-wide genotyping array 40203 2020-04-16 31488892 Masuda T 2019-09-05 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31488892 GWAS of five gynecologic diseases and cross-trait analysis in Japanese. Ovarian cancer (MTAG) 647 Japanese ancestry cases, 39,556 Japanese ancestry controls NA Illumina [7645193] (imputed) 22 ovarian carcinoma http://www.ebi.ac.uk/efo/EFO_0001075 GCST009829 Genome-wide genotyping array 40203 2020-04-16 31488892 Masuda T 2019-09-05 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31488892 GWAS of five gynecologic diseases and cross-trait analysis in Japanese. Endometrial cancer 909 Japanese ancestry cases, 39,556 Japanese ancestry controls NA Illumina [7645193] (imputed) 12 endometrial carcinoma http://www.ebi.ac.uk/efo/EFO_1001512 GCST009828 Genome-wide genotyping array 40465 2020-04-16 31488892 Masuda T 2019-09-05 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31488892 GWAS of five gynecologic diseases and cross-trait analysis in Japanese. Endometrial cancer (MTAG) 909 Japanese ancestry cases, 39,556 Japanese ancestry controls NA Illumina [7645193] (imputed) 9 endometrial carcinoma http://www.ebi.ac.uk/efo/EFO_1001512 GCST009827 Genome-wide genotyping array 40465 2020-04-16 31488892 Masuda T 2019-09-05 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31488892 GWAS of five gynecologic diseases and cross-trait analysis in Japanese. Gynecologic disease 7,315 Japanese ancestry cases, 39,556 Japanese ancestry controls NA Illumina [7645193] (imputed) 7 female reproductive system disease http://www.ebi.ac.uk/efo/EFO_0009549 GCST009822 Genome-wide genotyping array 46871 2020-04-16 31488892 Masuda T 2019-09-05 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31488892 GWAS of five gynecologic diseases and cross-trait analysis in Japanese. Cervical cancer 538 Japanese ancestry cases, 39,556 Japanese ancestry controls NA Illumina [7645193] (imputed) 72 cervical carcinoma http://www.ebi.ac.uk/efo/EFO_0001061 GCST009826 Genome-wide genotyping array 40094 2020-04-16 31488892 Masuda T 2019-09-05 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31488892 GWAS of five gynecologic diseases and cross-trait analysis in Japanese. Cervical cancer (MTAG) 538 Japanese ancestry cases, 39,556 Japanese ancestry controls NA Illumina [7645193] (imputed) 62 cervical carcinoma http://www.ebi.ac.uk/efo/EFO_0001061 GCST009825 Genome-wide genotyping array 40094 2020-04-16 31488892 Masuda T 2019-09-05 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31488892 GWAS of five gynecologic diseases and cross-trait analysis in Japanese. Gynecologic disease 7,975 Japanese ancestry cases, 39,556 Japanese ancestry controls NA Illumina [7645193] (imputed) 6 female reproductive system disease http://www.ebi.ac.uk/efo/EFO_0009549 GCST009824 Genome-wide genotyping array 47531 2020-04-16 31488892 Masuda T 2019-09-05 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31488892 GWAS of five gynecologic diseases and cross-trait analysis in Japanese. Gynecologic disease (multivariate analysis) up to 7,975 Japanese ancestry cases, 39,556 Japanese ancestry controls NA Illumina [7645193] (imputed) 15 female reproductive system disease http://www.ebi.ac.uk/efo/EFO_0009549 GCST009823 Genome-wide genotyping array 47531 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Height 6,044 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST90013304 Genome-wide sequencing [NA] 6044 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Body mass index 6,039 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST90013305 Genome-wide sequencing [NA] 6039 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Calcium levels 6,020 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 calcium measurement http://www.ebi.ac.uk/efo/EFO_0004838 GCST90013306 Genome-wide sequencing [NA] 6020 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Chloride levels 6,018 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 chloride measurement http://www.ebi.ac.uk/efo/EFO_0009284 GCST90013307 Genome-wide sequencing [NA] 6018 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Iron levels 6,010 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 serum iron measurement http://www.ebi.ac.uk/efo/EFO_0006332 GCST90013308 Genome-wide sequencing [NA] 6010 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Magnesium levels 5,996 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 magnesium measurement http://www.ebi.ac.uk/efo/EFO_0004845 GCST90013309 Genome-wide sequencing [NA] 5996 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Potassium levels 6,017 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 potassium measurement http://www.ebi.ac.uk/efo/EFO_0009283 GCST90013310 Genome-wide sequencing [NA] 6017 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Sodium levels 6,018 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 sodium measurement http://www.ebi.ac.uk/efo/EFO_0009282 GCST90013311 Genome-wide sequencing [NA] 6018 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Bicarbonate levels 6,017 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 blood bicarbonate measurement http://www.ebi.ac.uk/efo/EFO_0011012 GCST90013312 Genome-wide sequencing [NA] 6017 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Serum alkaline phosphatase levels 6,012 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 alkaline phosphatase measurement http://www.ebi.ac.uk/efo/EFO_0004533 GCST90013313 Genome-wide sequencing [NA] 6012 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Alanine aminotransferase levels 6,018 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 serum alanine aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004735 GCST90013314 Genome-wide sequencing [NA] 6018 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Aspartate aminotransferase levels 6,018 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 aspartate aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004736 GCST90013315 Genome-wide sequencing [NA] 6018 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Creatine kinase levels 5,344 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 creatine kinase measurement http://www.ebi.ac.uk/efo/EFO_0004534 GCST90013316 Genome-wide sequencing [NA] 5344 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Gamma glutamyl transferase levels 4,650 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 serum gamma-glutamyl transferase measurement http://www.ebi.ac.uk/efo/EFO_0004532 GCST90013317 Genome-wide sequencing [NA] 4650 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Activated partial thromboplastin time 5,988 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 partial thromboplastin time http://www.ebi.ac.uk/efo/EFO_0004310 GCST90013318 Genome-wide sequencing [NA] 5988 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Prothrombin time 5,989 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 prothrombin time measurement http://www.ebi.ac.uk/efo/EFO_0008390 GCST90013319 Genome-wide sequencing [NA] 5989 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. International normalisation ratio 5,987 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 prothrombin time measurement http://www.ebi.ac.uk/efo/EFO_0008390 GCST90013320 Genome-wide sequencing [NA] 5987 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Fibrinogen 5,984 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 fibrinogen measurement http://www.ebi.ac.uk/efo/EFO_0004623 GCST90013321 Genome-wide sequencing [NA] 5984 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. White blood cell count 6,007 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 myeloid white cell count http://www.ebi.ac.uk/efo/EFO_0007988 GCST90013322 Genome-wide sequencing [NA] 6007 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Red blood cell count 6,007 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 erythrocyte count http://www.ebi.ac.uk/efo/EFO_0004305 GCST90013323 Genome-wide sequencing [NA] 6007 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Mean corpuscular hemoglobin concentration 6,007 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90013324 Genome-wide sequencing [NA] 6007 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Mean corpuscular hemoglobin 6,007 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 mean corpuscular hemoglobin http://www.ebi.ac.uk/efo/EFO_0004527 GCST90013325 Genome-wide sequencing [NA] 6007 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Mean corpuscular volume 6,007 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST90013326 Genome-wide sequencing [NA] 6007 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Platelet count 5,935 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST90013327 Genome-wide sequencing [NA] 5935 2018-10-17 29785010 Khawaja AP 2018-05-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29785010 Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma. Intraocular pressure 139,555 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 133 intraocular pressure measurement http://www.ebi.ac.uk/efo/EFO_0004695 GCST006412 Genome-wide genotyping array 139555 2018-09-19 29739359 Graham PS 2018-05-08 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/29739359 Genome-wide association studies for diabetic macular edema and proliferative diabetic retinopathy. Diabetic macular edema in type 2 diabetes 270 European ancestry cases, 435 European ancestry controls NA Illumina [617130] 2 diabetic macular edema http://www.ebi.ac.uk/efo/EFO_0009321 GCST006282 Genome-wide genotyping array 705 2018-09-19 29739359 Graham PS 2018-05-08 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/29739359 Genome-wide association studies for diabetic macular edema and proliferative diabetic retinopathy. Proliferative diabetic retinopathy in type 2 diabetes 176 European ancestry cases, 435 European ancestry controls NA Illumina [617130] 2 proliferative diabetic retinopathy http://www.ebi.ac.uk/efo/EFO_0009322 GCST006283 Genome-wide genotyping array 611 2018-10-16 29743933 Wu B 2018-03-18 Comput Math Methods Med www.ncbi.nlm.nih.gov/pubmed/29743933 Fast and Accurate Genome-Wide Association Test of Multiple Quantitative Traits. Glycemic traits (multi-trait analysis) 5,947 European ancestry individuals NA NR [~ 2500000] (imputed) 5 fasting blood glucose measurement, glucose tolerance test, fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004465, http://www.ebi.ac.uk/efo/EFO_0004307, http://www.ebi.ac.uk/efo/EFO_0004466 GCST006404 Genome-wide genotyping array 5947 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Sitting height 6,034 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 sitting height measurement http://www.ebi.ac.uk/efo/EFO_0011011 GCST90013303 Genome-wide sequencing [NA] 6034 2020-09-01 30226566 Yamada Y 2018-09-04 Int J Mol Med www.ncbi.nlm.nih.gov/pubmed/30226566 Identification of 13 novel susceptibility loci for early-onset myocardial infarction, hypertension, or chronic kidney disease. Myocardial infarction 1,152 Japanese ancestry cases, 5,774 Japanese ancestry controls NA Illumina [31245] 21 myocardial infarction http://www.ebi.ac.uk/efo/EFO_0000612 GCST010476 Exome genotyping array 6926 2020-09-01 30226566 Yamada Y 2018-09-04 Int J Mol Med www.ncbi.nlm.nih.gov/pubmed/30226566 Identification of 13 novel susceptibility loci for early-onset myocardial infarction, hypertension, or chronic kidney disease. Chronic kidney disease 1,051 Japanese ancestry cases, 1,505 Japanese ancestry controls NA Illumina [31514] 11 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST010478 Exome genotyping array 2556 2020-09-01 30226566 Yamada Y 2018-09-04 Int J Mol Med www.ncbi.nlm.nih.gov/pubmed/30226566 Identification of 13 novel susceptibility loci for early-onset myocardial infarction, hypertension, or chronic kidney disease. Hypertension 3,444 Japanese ancestry cases, 4,636 Japanese ancestry controls NA Illumina [31276] 10 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST010477 Exome genotyping array [Exome array] 8080 2018-09-13 29970928 Zhu Z 2018-07-03 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29970928 Multi-level genomic analyses suggest new genetic variants involved in human memory. Short-term memory (digit-span task) 1,621 Chinese ancestry individuals 2,788 Chinese ancestry individuals Illumina [830937] 0 memory performance http://www.ebi.ac.uk/efo/EFO_0004874 GCST006253 Genome-wide genotyping array 1621 2018-09-13 29970928 Zhu Z 2018-07-03 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29970928 Multi-level genomic analyses suggest new genetic variants involved in human memory. Short-term memory (visuospatial task) 1,623 Chinese ancestry individuals 2,790 Chinese ancestry individuals Illumina [830937] 1 memory performance http://www.ebi.ac.uk/efo/EFO_0004874 GCST006254 Genome-wide genotyping array 1623 2018-09-13 29970928 Zhu Z 2018-07-03 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29970928 Multi-level genomic analyses suggest new genetic variants involved in human memory. Short-term memory (shared component of digit-span and visuospatial tasks) up to 1,623 Chinese ancestry individuals up to 2,790 Chinese ancestry individuals Illumina [up to 38219282] (imputed) 0 memory performance http://www.ebi.ac.uk/efo/EFO_0004874 GCST006255 Genome-wide genotyping array 1623 2018-09-13 29970928 Zhu Z 2018-07-03 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29970928 Multi-level genomic analyses suggest new genetic variants involved in human memory. Long-term memory (delayed word recall task) 1,522 Chinese ancestry individuals 1,862 Chinese ancestry individuals Illumina [up to 38219282] (imputed) 2 word list delayed recall measurement http://www.ebi.ac.uk/efo/EFO_0006805 GCST006256 Genome-wide genotyping array 1522 2018-07-20 29787419 Hrdlickova B 2018-05-21 Eur J Gastroenterol Hepatol www.ncbi.nlm.nih.gov/pubmed/29787419 A locus at 7p14.3 predisposes to refractory celiac disease progression from celiac disease. Refractory celiac disease type II 38 Dutch ancestry cases, 846 Dutch ancestry controls 56 European ancestry cases, 1,285 European ancestry controls Illumina [499626] 2 refractory celiac disease http://www.ebi.ac.uk/efo/EFO_0009266 GCST005928 Genome-wide genotyping array 884 2020-02-21 31879980 German CA 2019-12-26 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31879980 Ordered multinomial regression for genetic association analysis of ordinal phenotypes at Biobank scale. Hypertension 30,822 British ancestry normal blood pressure individuals, 25,242 British ancestry elevated blood pressure individuals, 50,461 British ancestry stage 1 hypertension individuals, 75,286 British ancestry stage 2 hypertension individuals, 3,754 British ancestry hypertension crisis individuals NA Affymetrix [464137] 52 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST009685 Genome-wide genotyping array 185568 2020-02-21 31879980 German CA 2019-12-26 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/31879980 Ordered multinomial regression for genetic association analysis of ordinal phenotypes at Biobank scale. Airflow obstruction in ever smokers 2,534 European ancestry unaffected individuals, 607 European ancestry stage 1 individuals, 1,424 European ancestry stage 2 individuals, 909 European ancestry stage 3 individuals, 487 European ancestry stage 4 individuals NA NR [630860] 2 pulmonary function measurement http://www.ebi.ac.uk/efo/EFO_0003892 GCST009684 Genome-wide genotyping array 5971 2019-03-13 30664634 Rask-Andersen M 2019-01-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30664634 Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects. Body fat distribution (arm fat ratio) 55,006 British ancestry males, 61,132 British ancestry females 112,425 British ancestry males, 133,936 British ancestry females Affymetrix [25472837] (imputed) 144 body fat distribution http://www.ebi.ac.uk/efo/EFO_0004341 GCST007293 Genome-wide genotyping array 116138 2019-03-13 30664634 Rask-Andersen M 2019-01-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30664634 Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects. Body fat distribution (leg fat ratio) 55,006 British ancestry males, 61,132 British ancestry females 112,425 British ancestry males, 133,936 British ancestry females Affymetrix [25472837] (imputed) 176 body fat distribution http://www.ebi.ac.uk/efo/EFO_0004341 GCST007295 Genome-wide genotyping array 116138 2019-03-13 30664634 Rask-Andersen M 2019-01-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30664634 Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects. Body fat distribution (trunk fat ratio) 55,006 British ancestry males, 61,132 British ancestry females 112,425 British ancestry males, 133,936 British ancestry females Affymetrix [25472837] (imputed) 186 body fat distribution http://www.ebi.ac.uk/efo/EFO_0004341 GCST007294 Genome-wide genotyping array 116138 2020-08-17 31926635 Coleman JRI 2019-11-01 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/31926635 The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls. Bipolar disorder or major depressive disorder 164,933 European ancestry major depressive disorder cases, 20,352 European ancestry bipolar disorder cases, 439,741 European ancestry controls NA NR [NR] (imputed) 92 unipolar depression, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000289 GCST010416 Genome-wide genotyping array 625026 2020-01-28 31930058 Niu LD 2019-11-01 Ann Transl Med www.ncbi.nlm.nih.gov/pubmed/31930058 Genome-wide association study of cerebrospinal fluid neurofilament light levels in non-demented elders. Cerebrospinal fluid neurofilament light levels 263 European ancestry individuals NA Illumina [441611] 3 neurofilament light chain measurement http://www.ebi.ac.uk/efo/EFO_0009178 GCST009517 Genome-wide genotyping array 263 2020-03-30 31936517 Cox JW 2020-01-09 J Clin Med www.ncbi.nlm.nih.gov/pubmed/31936517 Genome-Wide Association Study of Opioid Cessation. Opioid use cessation 1,130 African American individuals, 2,919 European ancestry individuals NA Illumina [NR] (imputed) 7 Opioid use measurement http://www.ebi.ac.uk/efo/EFO_0009937 GCST009796 Genome-wide genotyping array 4049 2020-10-15 31985465 Chen SD 2020-01-20 J Alzheimers Dis www.ncbi.nlm.nih.gov/pubmed/31985465 Genome-Wide Association Study Identifies SLAMF1 Affecting the Rate of Memory Decline. Memory decline 709 European ancestry individuals NA Illumina [1197412] 3 cognitive decline measurement, memory performance http://www.ebi.ac.uk/efo/EFO_0007710, http://www.ebi.ac.uk/efo/EFO_0004874 GCST010679 Genome-wide genotyping array 709 2020-10-15 31982041 Guillen-Guio B 2020-01-23 Lancet Respir Med www.ncbi.nlm.nih.gov/pubmed/31982041 Sepsis-associated acute respiratory distress syndrome in individuals of European ancestry: a genome-wide association study. Acute respiratory distress syndrome in sepsis 274 European ancestry cases, 316 European ancestry controls 359 European ancestry cases, 986 European ancestry controls Affymetrix [7984208] (imputed) 2 acute respiratory distress syndrome http://www.ebi.ac.uk/efo/EFO_1000637 GCST010680 Genome-wide genotyping array 590 2020-03-03 31996736 Elsheikh SSM 2020-01-29 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31996736 Genome-Wide Association Study of Brain Connectivity Changes for Alzheimer's Disease. Longitudinal brain connectivity change (Louvain modularity) 57 European ancestry individuals NA NR [9015039] (imputed) 12 brain connectivity measurement http://www.ebi.ac.uk/efo/EFO_0005210 GCST009730 Genome-wide genotyping array 57 2020-03-03 31996736 Elsheikh SSM 2020-01-29 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31996736 Genome-Wide Association Study of Brain Connectivity Changes for Alzheimer's Disease. Longitudinal brain connectivity change (transitivity) 57 European ancestry individuals NA NR [9015039] (imputed) 8 brain connectivity measurement http://www.ebi.ac.uk/efo/EFO_0005210 GCST009729 Genome-wide genotyping array 57 2020-03-03 31996736 Elsheikh SSM 2020-01-29 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31996736 Genome-Wide Association Study of Brain Connectivity Changes for Alzheimer's Disease. Longitudinal brain connectivity change (global efficiency) 57 European ancestry individuals NA NR [9015039] (imputed) 7 brain connectivity measurement http://www.ebi.ac.uk/efo/EFO_0005210 GCST009728 Genome-wide genotyping array 57 2020-03-03 31996736 Elsheikh SSM 2020-01-29 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31996736 Genome-Wide Association Study of Brain Connectivity Changes for Alzheimer's Disease. Longitudinal brain connectivity change (characteristic path length) 57 European ancestry individuals NA NR [9015039] (imputed) 4 brain connectivity measurement http://www.ebi.ac.uk/efo/EFO_0005210 GCST009727 Genome-wide genotyping array 57 2020-05-13 32005204 Alblooshi H 2020-01-31 BMC Psychiatry www.ncbi.nlm.nih.gov/pubmed/32005204 Stratified analyses of genome wide association study data reveal haplotypes for a candidate gene on chromosome 2 (KIAA1211L) is associated with opioid use in patients of Arabian descent. Opioid use disorder 199 Arabian ancestry cases, 253 Arabian ancestry controls NA Illumina [1879623] 3 opioid use disorder http://www.ebi.ac.uk/efo/EFO_0010702 GCST009964 Genome-wide genotyping array 452 2020-09-29 31985003 Boocock J 2020-01-27 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31985003 Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control. Urate levels 110,238 European ancestry individuals, 21,471 East Asian individuals NA NR [NR] (imputed) 33 urate measurement http://www.ebi.ac.uk/efo/EFO_0004531 GCST010637 Genome-wide genotyping array 131709 2020-03-30 31998841 Thompson A 2020-01-15 Sci Adv www.ncbi.nlm.nih.gov/pubmed/31998841 Functional validity, role, and implications of heavy alcohol consumption genetic loci. Alcohol consumption (heavy vs. light/non-drinkers) 21,967 British ancestry cases, 103,282 British ancestry controls 47,967 European ancestry individuals Affymetrix [11141077] (imputed) 10 alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0007878 GCST009797 Genome-wide genotyping array 125249 2018-06-26 29784950 Sawai H 2018-05-21 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29784950 Genome-wide association study identified new susceptible genetic variants in HLA class I region for hepatitis B virus-related hepatocellular carcinoma. Hepatocellular carcinoma in hepatitis B infection 473 Japanese ancestry chronic hepatitis and hepatocellular carcinoma cases, 516 Japanese ancestry asymptomatic carriers or chronic hepatitis cases without hepatocellular carcinoma 153 Japanese ancestry chronic hepatitis and hepatocellular carcinoma cases, 614 Japanese ancestry asymptomatic carriers or chronic hepatitis cases without hepatocellular carcinoma, 94 Chinese ancestry chronic hepatitis and hepatocellular carcinoma cases, 187 Chinese ancestry asymptomatic carriers or chronic hepatitis cases without hepatocellular carcinoma, 185 Thai ancestry chronic hepatitis and hepatocellular carcinoma cases, 198 Thai ancestry asymptomatic carriers or chronic hepatitis cases without hepatocellular carcinoma Affymetrix [447830] 7 hepatocellular carcinoma http://www.ebi.ac.uk/efo/EFO_0000182 GCST005746 Genome-wide genotyping array 989 2020-03-31 31959922 Matoba N 2020-01-20 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31959922 GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits. Alcohol consumption (drinks per week) 58,610 Japanese ancestry individuals NA Illumina [6108828] (imputed) 3 alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0007878 GCST009800 Genome-wide genotyping array 58610 2020-03-31 31959922 Matoba N 2020-01-20 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31959922 GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits. Coffee consumption 152,634 Japanese ancestry individuals NA Illumina [6108828] (imputed) 16 coffee consumption measurement http://www.ebi.ac.uk/efo/EFO_0006781 GCST009801 Genome-wide genotyping array 152634 2020-03-31 31959922 Matoba N 2020-01-20 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31959922 GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits. Green tea consumption 152,653 Japanese ancestry individuals NA Illumina [6108828] (imputed) 1 tea consumption measurement http://www.ebi.ac.uk/efo/EFO_0010091 GCST009802 Genome-wide genotyping array 152653 2020-03-31 31959922 Matoba N 2020-01-20 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31959922 GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits. Milk consumption 152,965 Japanese ancestry individuals NA Illumina [6108828] (imputed) 1 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST009803 Genome-wide genotyping array 152965 2020-03-31 31959922 Matoba N 2020-01-20 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31959922 GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits. Yoghurt consumption 83,150 Japanese ancestry men, 69,757 Japanese ancestry women NA Illumina [6108828] (imputed) 2 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST009804 Genome-wide genotyping array 152907 2020-03-31 31959922 Matoba N 2020-01-20 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31959922 GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits. Cheese consumption 152,714 Japanese ancestry individuals NA Illumina [6108828] (imputed) 0 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST009805 Genome-wide genotyping array 152714 2020-03-31 31959922 Matoba N 2020-01-20 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31959922 GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits. Natto consumption 152,678 Japanese ancestry individuals NA Illumina [6108828] (imputed) 1 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST009806 Genome-wide genotyping array 152678 2020-03-31 31959922 Matoba N 2020-01-20 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31959922 GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits. Tofu consumption 152,943 Japanese ancestry individuals NA Illumina [6108828] (imputed) 1 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST009807 Genome-wide genotyping array 152943 2020-03-31 31959922 Matoba N 2020-01-20 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31959922 GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits. Fish intake frequency 153,048 Japanese ancestry individuals NA Illumina [6108828] (imputed) 1 fish consumption measurement http://www.ebi.ac.uk/efo/EFO_0010139 GCST009808 Genome-wide genotyping array 153048 2020-03-31 31959922 Matoba N 2020-01-20 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31959922 GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits. Small whole fish consumption 82,791 Japanese ancestry men, 69,486 Japanese ancestry women NA Illumina [6108828] (imputed) 1 fish consumption measurement http://www.ebi.ac.uk/efo/EFO_0010139 GCST009809 Genome-wide genotyping array 152277 2020-03-31 31959922 Matoba N 2020-01-20 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31959922 GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits. Vegetable consumption 153,001 Japanese ancestry individuals NA Illumina [6108828] (imputed) 0 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST009810 Genome-wide genotyping array 153001 2020-03-31 31959922 Matoba N 2020-01-20 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31959922 GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits. Meat consumption 152,857 Japanese ancestry individuals NA Illumina [6108828] (imputed) 0 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST009811 Genome-wide genotyping array 152857 2020-03-31 31959922 Matoba N 2020-01-20 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31959922 GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits. Alcohol consumption (drinkers vs non-drinkers) 83,713 Japanese ancestry ever drinkers, 81,371 Japanese ancestry never drinkers NA Illumina [6108828] (imputed) 6 alcohol drinking http://www.ebi.ac.uk/efo/EFO_0004329 GCST009799 Genome-wide genotyping array 165084 2018-10-09 29779033 Hishida A 2018-05-18 Am J Nephrol www.ncbi.nlm.nih.gov/pubmed/29779033 Genome-Wide Association Study of Renal Function Traits: Results from the Japan Multi-Institutional Collaborative Cohort Study. Chronic kidney disease 939 Japanese ancestry cases, 10,344 Japanese ancestry controls 38,143 Japanese ancestry cases, 110,686 Japanese ancestry controls Illumina [6288024] (imputed) 0 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST006391 Genome-wide genotyping array 11283 2018-10-09 29779033 Hishida A 2018-05-18 Am J Nephrol www.ncbi.nlm.nih.gov/pubmed/29779033 Genome-Wide Association Study of Renal Function Traits: Results from the Japan Multi-Institutional Collaborative Cohort Study. Estimated glomerular filtration rate 11,283 Japanese ancestry individuals 148,829 Japanese ancestry individuals Illumina [6288024] (imputed) 4 glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0005208 GCST006392 Genome-wide genotyping array 11283 2018-10-09 29779033 Hishida A 2018-05-18 Am J Nephrol www.ncbi.nlm.nih.gov/pubmed/29779033 Genome-Wide Association Study of Renal Function Traits: Results from the Japan Multi-Institutional Collaborative Cohort Study. Serum creatinine levels 11,283 Japanese ancestry individuals 148,829 Japanese ancestry individuals Illumina [6288024] (imputed) 4 creatinine measurement http://www.ebi.ac.uk/efo/EFO_0004518 GCST006393 Genome-wide genotyping array 11283 2019-03-27 29786918 Vonk JM 2018-05-22 Clin Exp Allergy www.ncbi.nlm.nih.gov/pubmed/29786918 Novel genes and insights in complete asthma remission. Clinical remission in asthma 178 European ancestry remitted asthma cases, 612 European ancestry persistent asthma controls 135 European ancestry remitted asthma cases, 321 European ancestry persistent asthma controls Illumina [156954] 0 remission http://www.ebi.ac.uk/efo/EFO_0009785 GCST007423 Genome-wide genotyping array 790 2019-03-27 29786918 Vonk JM 2018-05-22 Clin Exp Allergy www.ncbi.nlm.nih.gov/pubmed/29786918 Novel genes and insights in complete asthma remission. Complete remission in asthma 55 European ancestry remitted asthma cases, 612 European ancestry persistent asthma controls 21 European ancestry remitted asthma cases, 321 European ancestry persistent asthma controls Illumina [156954] 1 remission http://www.ebi.ac.uk/efo/EFO_0009785 GCST007424 Genome-wide genotyping array 667 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Mean platelet volume 6,006 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 mean platelet volume http://www.ebi.ac.uk/efo/EFO_0004584 GCST90013328 Genome-wide sequencing [NA] 6006 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Hematocrit 6,007 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST90013329 Genome-wide sequencing [NA] 6007 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Hemoglobin 6,006 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST90013330 Genome-wide sequencing [NA] 6006 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Total cholesterol levels 6,017 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST90013331 Genome-wide sequencing [NA] 6017 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. High density lipoprotein cholesterol levels 6,013 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST90013332 Genome-wide sequencing [NA] 6013 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Low density lipoprotein cholesterol levels 5,972 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST90013333 Genome-wide sequencing [NA] 5972 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Triglycerides 6,017 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST90013334 Genome-wide sequencing [NA] 6017 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Serum total protein level 6,017 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 total blood protein measurement http://www.ebi.ac.uk/efo/EFO_0004536 GCST90013335 Genome-wide sequencing [NA] 6017 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Serum albumin levels 6,018 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 serum albumin measurement http://www.ebi.ac.uk/efo/EFO_0004535 GCST90013336 Genome-wide sequencing [NA] 6018 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Ferritin levels 5,947 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 ferritin measurement http://www.ebi.ac.uk/efo/EFO_0004459 GCST90013337 Genome-wide sequencing [NA] 5947 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. C-peptide levels 5,925 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 C-peptide measurement http://www.ebi.ac.uk/efo/EFO_0005187 GCST90013338 Genome-wide sequencing [NA] 5925 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Pro B-type natriuretic peptide 5,516 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90013339 Genome-wide sequencing [NA] 5516 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Iron status biomarkers (total iron binding capacity) 6,010 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 total iron binding capacity http://www.ebi.ac.uk/efo/EFO_0006334 GCST90013340 Genome-wide sequencing [NA] 6010 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Unsaturated iron binding capacity 5,956 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 total iron binding capacity http://www.ebi.ac.uk/efo/EFO_0006334 GCST90013341 Genome-wide sequencing [NA] 5956 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Total bilirubin levels 6,018 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004570 GCST90013342 Genome-wide sequencing [NA] 6018 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Uric acid levels 6,013 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880615] 0 uric acid measurement http://www.ebi.ac.uk/efo/EFO_0004761 GCST90013343 Genome-wide sequencing [NA] 6013 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Serum folate levels 5,944 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 red blood cell folate measurement http://www.ebi.ac.uk/efo/EFO_0009703 GCST90013344 Genome-wide sequencing [NA] 5944 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Serum creatinine levels 6,018 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 creatinine measurement http://www.ebi.ac.uk/efo/EFO_0004518 GCST90013345 Genome-wide sequencing [NA] 6018 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Homocysteine levels 5,727 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 homocysteine measurement http://www.ebi.ac.uk/efo/EFO_0004578 GCST90013346 Genome-wide sequencing [NA] 5727 2021-03-03 33623009 Thareja G 2021-02-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33623009 Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Vitamin B12 levels 5,865 Greater Middle Eastern (Middle Eastern, North African or Persian) individuals NA Illumina [7880617] 0 vitamin B12 measurement http://www.ebi.ac.uk/efo/EFO_0004620 GCST90013347 Genome-wide sequencing [NA] 5865 2020-07-08 32059762 Manousaki D 2020-02-05 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32059762 Genome-wide Association Study for Vitamin D Levels Reveals 69 Independent Loci. Serum 25-Hydroxyvitamin D levels 443,734 European ancestry individuals NA Affymetrix [16668957] (imputed) 138 vitamin D measurement http://www.ebi.ac.uk/efo/EFO_0004631 GCST010144 Genome-wide genotyping array 443734 2018-07-19 29782485 Rueger S 2018-05-21 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29782485 Evaluation and application of summary statistic imputation to discover new height-associated loci. Height 253,288 European ancestry individuals 336,474 European ancestry individuals NR [9276018] (imputed) 41 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST005908 Genome-wide genotyping array 253288 2021-08-13 32889700 Qin N 2020-09-05 Front Med www.ncbi.nlm.nih.gov/pubmed/32889700 Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma. Lung adenocarcinoma 15,581 Chinese or European ancestry cases, 27,355 Chinese or European ancestry controls NA NR [NR] (imputed) 23 lung adenocarcinoma http://www.ebi.ac.uk/efo/EFO_0000571 GCST012201 Genome-wide genotyping array 42936 2021-08-13 32889700 Qin N 2020-09-05 Front Med www.ncbi.nlm.nih.gov/pubmed/32889700 Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma. Squamous cell lung carcinoma 8,350 Chinese or European ancestry cases, 27,355 Chinese or European ancestry controls NA NR [NR] (imputed) 13 squamous cell lung carcinoma http://www.ebi.ac.uk/efo/EFO_0000708 GCST012200 Genome-wide genotyping array 35705 2021-08-13 32889700 Qin N 2020-09-05 Front Med www.ncbi.nlm.nih.gov/pubmed/32889700 Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma. Non-small cell lung cancer 27,120 Chinese or European ancestry cases, 27,355 Chinese or European ancestry controls NA NR [NR] (imputed) 28 non-small cell lung carcinoma http://www.ebi.ac.uk/efo/EFO_0003060 GCST012199 Genome-wide genotyping array 54475 2018-07-23 29698431 Roosenboom J 2018-04-26 PLoS One www.ncbi.nlm.nih.gov/pubmed/29698431 Mapping genetic variants for cranial vault shape in humans. Maximum cranial length 4,419 European ancestry individuals NA Illumina [at least 567677] (imputed) 22 cranial vault morphology measurement http://www.ebi.ac.uk/efo/EFO_0009278 GCST005938 Genome-wide genotyping array 4419 2018-07-23 29698431 Roosenboom J 2018-04-26 PLoS One www.ncbi.nlm.nih.gov/pubmed/29698431 Mapping genetic variants for cranial vault shape in humans. Cephalic index 4,419 European ancestry individuals NA Illumina [at least 567677] (imputed) 14 cranial vault morphology measurement http://www.ebi.ac.uk/efo/EFO_0009278 GCST005939 Genome-wide genotyping array 4419 2018-07-23 29698431 Roosenboom J 2018-04-26 PLoS One www.ncbi.nlm.nih.gov/pubmed/29698431 Mapping genetic variants for cranial vault shape in humans. Maximum cranial width 4,419 European ancestry individuals NA Illumina [at least 567677] (imputed) 20 cranial vault morphology measurement http://www.ebi.ac.uk/efo/EFO_0009278 GCST005940 Genome-wide genotyping array 4419 2020-09-20 32887874 Saw J 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887874 Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction. Spontaneous coronary artery dissection up to 243 European ancestry cases, up to 23 East Asian ancestry cases, up to 4,816 European ancestry controls, up to 447 East Asian ancestry controls up to 149 European ancestry cases, up to 14 East Asian ancestry cases, up to 2,935 European ancestry controls, up to 272 East Asian ancestry controls Illumina [6690240] (imputed) 17 spontaneous coronary artery dissection http://www.ebi.ac.uk/efo/EFO_0010820 GCST90000582 Genome-wide genotyping array 5529 2020-09-20 32887874 Saw J 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887874 Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction. Spontaneous coronary artery dissection up to 221 European ancestry female cases, up to 20 East Asian ancestry female cases, up to 4,258 European ancestry female controls, up to 395 East Asian ancestry female controls up to 134 European ancestry female cases, up to 12 East Asian ancestry female cases, up to 2,608 European ancestry female controls, up to 242 East Asian female controls Illumina [6690240] (imputed) 4 spontaneous coronary artery dissection http://www.ebi.ac.uk/efo/EFO_0010820 GCST90000583 Genome-wide genotyping array 4894 2020-07-21 32203549 Richardson TG 2020-03-23 PLoS Med www.ncbi.nlm.nih.gov/pubmed/32203549 Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis. LDL cholesterol levels 440,546 European ancestry individuals NA Affymetrix [NR] (imputed) 229 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST010245 Genome-wide genotyping array 440546 2020-07-21 32203549 Richardson TG 2020-03-23 PLoS Med www.ncbi.nlm.nih.gov/pubmed/32203549 Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis. Triglyceride levels 441,016 European ancestry individuals NA Affymetrix [NR] (imputed) 440 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST010244 Genome-wide genotyping array 441016 2020-07-21 32203549 Richardson TG 2020-03-23 PLoS Med www.ncbi.nlm.nih.gov/pubmed/32203549 Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis. Apolipoprotein B levels 439,214 European ancestry individuals NA Affymetrix [NR] (imputed) 255 apolipoprotein B measurement http://www.ebi.ac.uk/efo/EFO_0004615 GCST010243 Genome-wide genotyping array 439214 2020-07-21 32203549 Richardson TG 2020-03-23 PLoS Med www.ncbi.nlm.nih.gov/pubmed/32203549 Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis. HDL cholesterol levels 403,943 European ancestry individuals NA Affymetrix [NR] (imputed) 534 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST010242 Genome-wide genotyping array 403943 2020-07-21 32203549 Richardson TG 2020-03-23 PLoS Med www.ncbi.nlm.nih.gov/pubmed/32203549 Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis. Apolipoprotein A1 levels 393,193 European ancestry individuals NA Affymetrix [NR] (imputed) 440 apolipoprotein A 1 measurement http://www.ebi.ac.uk/efo/EFO_0004614 GCST010241 Genome-wide genotyping array 393193 2018-09-18 30013178 Kowalec K 2018-07-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30013178 Common variation near IRF6 is associated with IFN-β-induced liver injury in multiple sclerosis. Drug-induced liver injury in interferon-beta-treated multiple sclerosis 38 European ancestry cases, 113 European ancestry controls 18 European ancestry cases, 13 European ancestry controls Illumina [up to 1705969] (imputed) 1 response to interferon beta, drug-induced liver injury http://purl.obolibrary.org/obo/GO_0035456, http://www.ebi.ac.uk/efo/EFO_0004228 GCST006270 Genome-wide genotyping array 151 2018-11-12 30009487 Schoeler NE 2018-07-16 Epilepsia www.ncbi.nlm.nih.gov/pubmed/30009487 Genome-wide association study: Exploring the genetic basis for responsiveness to ketogenic dietary therapies for drug-resistant epilepsy. Response to ketogenic dietary therapies in epilepsy 123 responders, 112 non-responders NA Illumina [4819069] (imputed) 1 response to ketogenic diet http://www.ebi.ac.uk/efo/EFO_0009372 GCST006567 Genome-wide genotyping array 235 2018-10-17 30013184 Waage J 2018-07-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30013184 Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis. Allergic rhinitis 59,762 European and unknown ancestry cases, 152,358 European and unknown ancestry controls 60,720 European ancestry cases, 618,527 European ancestry controls Affymetrix, Illumina, Perlegen [16531985] (imputed) 44 allergic rhinitis http://www.ebi.ac.uk/efo/EFO_0005854 GCST006409 Genome-wide genotyping array 212120 2018-10-17 30013184 Waage J 2018-07-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30013184 Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis. Allergic sensitization 8,040 European ancestry cases, 16,441 European ancestry controls NA Affymetrix, Illumina [16531985] (imputed) 19 allergic sensitization measurement http://www.ebi.ac.uk/efo/EFO_0005298 GCST006408 Genome-wide genotyping array 24481 2018-10-25 30013184 Waage J 2018-07-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30013184 Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis. Non-allergic rhinitis 2,028 European and unknown ancestry cases, 9,606 European and unknown ancestry controls NA Affymetrix, Illumina [12291687] (imputed) 0 non-allergic rhinitis http://www.ebi.ac.uk/efo/EFO_0009364 GCST006474 Genome-wide genotyping array 11634 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Hematocrit 20,704 Hispanic or Latin American individuals NA Affymetrix, Illumina [21000000] (imputed) 8 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST90012209 Genome-wide genotyping array 20704 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Hemoglobin concentration 16,186 African American individuals, 20,692 Hispanic or Latin American individuals, 29,379 European ancestry individuals, 630 Asian ancestry individuals, 601 Native American ancestry individuals, 381 individuals NA Affymetrix, Illumina [21000000] (imputed) 20 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90012210 Genome-wide genotyping array 67869 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Hemoglobin concentration 16,186 African American individuals NA Affymetrix, Illumina [21000000] (imputed) 6 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90012211 Genome-wide genotyping array 16186 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Hemoglobin concentration 29,379 European ancestry individuals NA Affymetrix, Illumina [21000000] (imputed) 11 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90012212 Genome-wide genotyping array 29379 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Hemoglobin concentration 20,692 Hispanic or Latin American individuals NA Affymetrix, Illumina [21000000] (imputed) 9 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90012213 Genome-wide genotyping array 20692 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Red cell distribution width 17,272 Hispanic or Latin American individuals NA Affymetrix, Illumina [21000000] (imputed) 16 red blood cell distribution width http://www.ebi.ac.uk/efo/EFO_0005192 GCST90012233 Genome-wide genotyping array 17272 2018-09-10 30012571 Jia X 2018-07-16 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/30012571 Strong Association of the HLA-DR/DQ Locus with Childhood Steroid-Sensitive Nephrotic Syndrome in the Japanese Population. Childhood steroid-sensitive nephrotic syndrome 224 Japanese ancestry cases, 412 Japanese ancestry controls 216 Japanese ancestry cases, 719 Japanese ancestry controls Affymetrix [4105543] (imputed) 1 nephrotic syndrome http://www.ebi.ac.uk/efo/EFO_0004255 GCST006246 Genome-wide genotyping array 636 2018-09-20 30014611 Weiss RB 2018-07-16 Ann Neurol www.ncbi.nlm.nih.gov/pubmed/30014611 Long-range genomic regulators of THBS1 and LTBP4 modify disease severity in Duchenne muscular dystrophy. Age at loss of ambulation in Duchenne muscular dystrophy 243 European ancestry cases, 10 cases NA Illumina [1735619] 47 Duchenne muscular dystrophy, disease progression measurement http://www.orpha.net/ORDO/Orphanet_98896, http://www.ebi.ac.uk/efo/EFO_0008336 GCST006286 Genome-wide genotyping array 253 2018-09-18 30031151 Virtanen VB 2018-07-18 Eur J Med Genet www.ncbi.nlm.nih.gov/pubmed/30031151 Noncoding RET variants explain the strong association with Hirschsprung disease in patients without rare coding sequence variant. Hirschsprung disease 105 European ancestry cases, 386 European ancestry controls 154 Swedish ancestry cases, 177 European ancestry controls Illumina [8432870] (imputed) 0 Hirschsprung disease http://www.orpha.net/ORDO/Orphanet_388 GCST006272 Genome-wide genotyping array 491 2018-09-18 30031151 Virtanen VB 2018-07-18 Eur J Med Genet www.ncbi.nlm.nih.gov/pubmed/30031151 Noncoding RET variants explain the strong association with Hirschsprung disease in patients without rare coding sequence variant. Hirschsprung disease 68 European ancestry cases, 386 European ancestry controls NA Illumina [8432870] (imputed) 1 Hirschsprung disease http://www.orpha.net/ORDO/Orphanet_388 GCST006271 Genome-wide genotyping array 454 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Mean corpuscular hemoglobin 8,694 African American individuals, 17,400 Hispanic or Latin American individuals, 14,693 European ancestry individuals, 127 Asian ancestry individuals, 20 Native American ancestry individuals, 382 individuals NA Affymetrix, Illumina [21000000] (imputed) 39 mean corpuscular hemoglobin http://www.ebi.ac.uk/efo/EFO_0004527 GCST90012214 Genome-wide genotyping array 41316 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Mean corpuscular hemoglobin 8,694 African American individuals NA Affymetrix, Illumina [21000000] (imputed) 11 mean corpuscular hemoglobin http://www.ebi.ac.uk/efo/EFO_0004527 GCST90012215 Genome-wide genotyping array 8694 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Mean corpuscular hemoglobin 14,693 European ancestry individuals NA Affymetrix, Illumina [21000000] (imputed) 23 mean corpuscular hemoglobin http://www.ebi.ac.uk/efo/EFO_0004527 GCST90012216 Genome-wide genotyping array 14693 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Mean corpuscular hemoglobin 17,400 Hispanic or Latin American individuals NA Affymetrix, Illumina [21000000] (imputed) 22 mean corpuscular hemoglobin http://www.ebi.ac.uk/efo/EFO_0004527 GCST90012217 Genome-wide genotyping array 17400 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Mean corpuscular hemoglobin concentration 16,353 African American individuals, 20,877 Hispanic or Latin American individuals, 29,587 European ancestry individuals, 635 Asian ancestry individuals, 20 Native American ancestry individuals, 384 individuals NA Affymetrix, Illumina [21000000] (imputed) 18 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90012218 Genome-wide genotyping array 67856 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Mean corpuscular hemoglobin concentration 16,353 African American individuals NA Affymetrix, Illumina [21000000] (imputed) 6 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90012219 Genome-wide genotyping array 16353 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Mean corpuscular hemoglobin concentration 29,587 European ancestry individuals NA Affymetrix, Illumina [21000000] (imputed) 6 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90012220 Genome-wide genotyping array 29587 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Mean corpuscular hemoglobin concentration 20,877 Hispanic or Latin American individuals NA Affymetrix, Illumina [21000000] (imputed) 9 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90012221 Genome-wide genotyping array 20877 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Mean corpuscular volume 8,556 African American individuals, 17,141 Hispanic or Latin American individuals, 14,483 European ancestry individuals, 125 Asian ancestry individuals, 594 Native American ancestry individuals, 377 individuals NA Affymetrix, Illumina [21000000] (imputed) 44 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST90012222 Genome-wide genotyping array 41276 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Mean corpuscular volume 8,556 African American individuals NA Affymetrix, Illumina [21000000] (imputed) 11 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST90012223 Genome-wide genotyping array 8556 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Mean corpuscular volume 14,483 European ancestry individuals NA Affymetrix, Illumina [21000000] (imputed) 23 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST90012224 Genome-wide genotyping array 14483 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Mean corpuscular volume 17,141 Hispanic or Latin American individuals NA Affymetrix, Illumina [21000000] (imputed) 23 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST90012225 Genome-wide genotyping array 17141 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Red blood cell count 8,679 African American individuals, 17,412 Hispanic or Latin American individuals, 14,690 European ancestry individuals, 127 Asian ancestry individuals, 20 Native American ancestry individuals, 382 individuals NA Affymetrix, Illumina [21000000] (imputed) 30 erythrocyte count http://www.ebi.ac.uk/efo/EFO_0004305 GCST90012226 Genome-wide genotyping array 41310 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Red blood cell count 8,679 African American individuals NA Affymetrix, Illumina [21000000] (imputed) 5 erythrocyte count http://www.ebi.ac.uk/efo/EFO_0004305 GCST90012227 Genome-wide genotyping array 8679 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Red blood cell count 14,690 European ancestry individuals NA Affymetrix, Illumina [21000000] (imputed) 12 erythrocyte count http://www.ebi.ac.uk/efo/EFO_0004305 GCST90012228 Genome-wide genotyping array 14690 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Red blood cell count 17,412 Hispanic or Latin American individuals NA Affymetrix, Illumina [21000000] (imputed) 15 erythrocyte count http://www.ebi.ac.uk/efo/EFO_0004305 GCST90012229 Genome-wide genotyping array 17412 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Red cell distribution width 6,141 African American individuals, 17,272 Hispanic or Latin American individuals, 9,611 European ancestry individuals, 123 Asian ancestry individuals, 20 Native American ancestry individuals, 382 individuals NA Affymetrix, Illumina [21000000] (imputed) 21 red blood cell distribution width http://www.ebi.ac.uk/efo/EFO_0005192 GCST90012230 Genome-wide genotyping array 33549 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Red cell distribution width 6,141 African American individuals NA Affymetrix, Illumina [21000000] (imputed) 2 red blood cell distribution width http://www.ebi.ac.uk/efo/EFO_0005192 GCST90012231 Genome-wide genotyping array 6141 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Red cell distribution width 9,611 European ancestry individuals NA Affymetrix, Illumina [21000000] (imputed) 8 red blood cell distribution width http://www.ebi.ac.uk/efo/EFO_0005192 GCST90012232 Genome-wide genotyping array 9611 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Red blood cell traits (multivariate analysis) 16,802 African American individuals NA Affymetrix, Illumina [21000000] (imputed) 11 erythrocyte count, mean corpuscular hemoglobin concentration, mean corpuscular volume, hematocrit, mean corpuscular hemoglobin, red blood cell distribution width http://www.ebi.ac.uk/efo/EFO_0004305, http://www.ebi.ac.uk/efo/EFO_0004528, http://www.ebi.ac.uk/efo/EFO_0004526, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0004527, http://www.ebi.ac.uk/efo/EFO_0005192 GCST90012203 Genome-wide genotyping array 16802 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Red blood cell traits (multivariate analysis) 29,513 European ancestry individuals NA Affymetrix, Illumina [21000000] (imputed) 11 erythrocyte count, mean corpuscular hemoglobin concentration, mean corpuscular volume, hematocrit, mean corpuscular hemoglobin, red blood cell distribution width http://www.ebi.ac.uk/efo/EFO_0004305, http://www.ebi.ac.uk/efo/EFO_0004528, http://www.ebi.ac.uk/efo/EFO_0004526, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0004527, http://www.ebi.ac.uk/efo/EFO_0005192 GCST90012204 Genome-wide genotyping array 29513 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Red blood cell traits (multivariate analysis) 20,697 Hispanic or Latin American individuals NA Affymetrix, Illumina [21000000] (imputed) 13 erythrocyte count, mean corpuscular hemoglobin concentration, mean corpuscular volume, hematocrit, mean corpuscular hemoglobin, red blood cell distribution width http://www.ebi.ac.uk/efo/EFO_0004305, http://www.ebi.ac.uk/efo/EFO_0004528, http://www.ebi.ac.uk/efo/EFO_0004526, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0004527, http://www.ebi.ac.uk/efo/EFO_0005192 GCST90012205 Genome-wide genotyping array 20697 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Hematocrit 16,184 African American individuals, 20,704 Hispanic or Latin American individuals, 29,383 European ancestry individuals, 631 Asian ancestry individuals, 601 Native American ancestry individuals, 381 individuals NA Affymetrix, Illumina [21000000] (imputed) 13 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST90012206 Genome-wide genotyping array 67884 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Hematocrit 16,184 African American individuals NA Affymetrix, Illumina [21000000] (imputed) 1 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST90012207 Genome-wide genotyping array 16184 2021-03-22 32171239 Hodonsky CJ 2020-03-14 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32171239 Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics. Hematocrit 29,383 European ancestry individuals NA Affymetrix, Illumina [21000000] (imputed) 11 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST90012208 Genome-wide genotyping array 29383 2018-08-10 26362759 Rothwell S 2015-09-11 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/26362759 Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups. Dermatomyositis or juvenile dermatomyositis 879 European dermatomyositis cases, 15,651 European juvenile dermatomyositis ancestry controls NA Illumina [90536] 4 dermatomyositis, juvenile dermatomyositis http://www.ebi.ac.uk/efo/EFO_0000398, http://www.ebi.ac.uk/efo/EFO_0000557 GCST006053 Targeted genotyping array [ImmunoChip] 16530 2018-08-10 26362759 Rothwell S 2015-09-11 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/26362759 Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups. Polymyositis 931 European ancestry cases, 15,651 European ancestry controls NA Illumina [90536] 8 polymyositis http://www.ebi.ac.uk/efo/EFO_0003063 GCST006052 Targeted genotyping array [ImmunoChip] 16582 2018-08-10 26362759 Rothwell S 2015-09-11 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/26362759 Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups. Idiopathic inflammatory myopathy 2,556 European ancestry cases, 15,651 European ancestry controls NA Illumina [90536] 7 myositis http://www.ebi.ac.uk/efo/EFO_0000783 GCST006051 Targeted genotyping array [ImmunoChip] 18207 2018-12-18 29670602 Moreau K 2018-04-04 Front Microbiol www.ncbi.nlm.nih.gov/pubmed/29670602 Human Genetic Susceptibility to Native Valve Staphylococcus aureus Endocarditis in Patients With S. aureus Bacteremia: Genome-Wide Association Study. Infective endocarditis in Staphylococcus aureus infection 67 European ancestry cases, 72 European ancestry controls 57 Danish ancestry cases, 123 Danish ancestry controls Illumina [631710] 0 bacterial endocarditis http://www.ebi.ac.uk/efo/EFO_1000830 GCST006805 Genome-wide genotyping array 139 2018-05-08 29520036 Stein MB 2018-03-08 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/29520036 Genome-wide analysis of insomnia disorder. Insomnia 2,297 European American cases, 334 African American cases, 606 Latino American cases, 9,176 European American controls, 2,345 African American controls, 2,893 Latino American controls NA Illumina [at least 360704] (imputed) 28 insomnia http://www.ebi.ac.uk/efo/EFO_0004698 GCST005566 Genome-wide genotyping array 17651 2019-02-12 29750799 Chao MJ 2018-05-11 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29750799 Population-specific genetic modification of Huntington's disease in Venezuela. Huntington's disease (age at onset) 374 Venezuelan ancestry individuals, 4,061 European ancestry individuals NA Illumina [NR] (imputed) 2 Huntington disease, age at onset http://www.orpha.net/ORDO/Orphanet_399, http://www.ebi.ac.uk/efo/EFO_0004847 GCST007113 Genome-wide genotyping array 4435 2018-07-20 29743610 Ostrom QT 2018-05-09 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29743610 Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21. Glioma 4,831 European ancestry male cases, 3,206 European ancestry female cases, 5,216 European ancestry male controls, 5,470 European ancestry female controls NA Affymetrix, Illumina [NR] (imputed) 17 glioma http://www.ebi.ac.uk/efo/EFO_0005543 GCST005931 Genome-wide genotyping array 18723 2018-07-20 29743610 Ostrom QT 2018-05-09 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29743610 Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21. Glioblastoma 2,835 European ancestry male cases, 1,682 European ancestry female cases, 5,216 European ancestry male controls, 5,470 European ancestry female controls NA Affymetrix, Illumina [NR] (imputed) 14 glioma http://www.ebi.ac.uk/efo/EFO_0005543 GCST005932 Genome-wide genotyping array 15203 2018-07-20 29743610 Ostrom QT 2018-05-09 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29743610 Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21. Non-glioblastoma glioma 1,716 European ancestry male cases, 1,320 European ancestry female cases, 5,216 European ancestry male controls, 5,470 European ancestry female controls NA Affymetrix, Illumina [NR] (imputed) 11 glioma http://www.ebi.ac.uk/efo/EFO_0005543 GCST005933 Genome-wide genotyping array 13722 2018-06-21 29751835 Hu H 2018-05-11 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/29751835 Genome-wide association study identified ATP6V1H locus influencing cerebrospinal fluid BACE activity. Cerebrospinal fluid beta-site APP cleaving enzyme levels 86 European ancestry Alzheimer's disease cases, 163 European ancestry mild cognitive impairment cases, 91 European ancestry controls NR Illumina [519442] 8 beta-secretase 1 measurement http://www.ebi.ac.uk/efo/EFO_0009179 GCST005714 Genome-wide genotyping array 340 2018-08-13 29752348 Rutten-Jacobs LCA 2018-05-11 Stroke www.ncbi.nlm.nih.gov/pubmed/29752348 Genetic Study of White Matter Integrity in UK Biobank (N=8448) and the Overlap With Stroke, Depression, and Dementia. White matter integrity (fractional anisotropy) 8,239 European ancestry individuals NA Affymetrix [up to 39131578] (imputed) 2 white matter integrity http://www.ebi.ac.uk/efo/EFO_0004641 GCST006063 Genome-wide genotyping array 8239 2018-08-13 29752348 Rutten-Jacobs LCA 2018-05-11 Stroke www.ncbi.nlm.nih.gov/pubmed/29752348 Genetic Study of White Matter Integrity in UK Biobank (N=8448) and the Overlap With Stroke, Depression, and Dementia. White matter integrity (mean diffusivity) 8,239 European ancestry individuals NA Affymetrix [up to 39131578] (imputed) 2 white matter integrity http://www.ebi.ac.uk/efo/EFO_0004641 GCST006064 Genome-wide genotyping array 8239 2018-08-13 29752348 Rutten-Jacobs LCA 2018-05-11 Stroke www.ncbi.nlm.nih.gov/pubmed/29752348 Genetic Study of White Matter Integrity in UK Biobank (N=8448) and the Overlap With Stroke, Depression, and Dementia. White matter hyperintensity volume 8,429 European ancestry individuals NA Affymetrix [up to 39131578] (imputed) 4 white matter hyperintensity measurement http://www.ebi.ac.uk/efo/EFO_0005665 GCST006062 Genome-wide genotyping array 8429 2018-07-12 29738550 de Oliveira Otto MC 2018-05-08 PLoS One www.ncbi.nlm.nih.gov/pubmed/29738550 Genome-wide association meta-analysis of circulating odd-numbered chain saturated fatty acids: Results from the CHARGE Consortium. Circulating odd-numbered chain saturated fatty acid levels (C15:0) 11,494 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 15 fatty acid measurement http://www.ebi.ac.uk/efo/EFO_0005110 GCST005869 Genome-wide genotyping array 11494 2018-07-12 29738550 de Oliveira Otto MC 2018-05-08 PLoS One www.ncbi.nlm.nih.gov/pubmed/29738550 Genome-wide association meta-analysis of circulating odd-numbered chain saturated fatty acids: Results from the CHARGE Consortium. Circulating odd-numbered chain saturated fatty acid levels (C17:0) 6,016 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 15 fatty acid measurement http://www.ebi.ac.uk/efo/EFO_0005110 GCST005868 Genome-wide genotyping array 6016 2018-07-12 29738550 de Oliveira Otto MC 2018-05-08 PLoS One www.ncbi.nlm.nih.gov/pubmed/29738550 Genome-wide association meta-analysis of circulating odd-numbered chain saturated fatty acids: Results from the CHARGE Consortium. Circulating odd-numbered chain saturated fatty acid levels (C15:0+C17:0) 6,016 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 15 fatty acid measurement http://www.ebi.ac.uk/efo/EFO_0005110 GCST005866 Genome-wide genotyping array 6016 2018-07-12 29738550 de Oliveira Otto MC 2018-05-08 PLoS One www.ncbi.nlm.nih.gov/pubmed/29738550 Genome-wide association meta-analysis of circulating odd-numbered chain saturated fatty acids: Results from the CHARGE Consortium. Circulating odd-numbered chain saturated fatty acid levels (C19:0) 1,910 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 15 fatty acid measurement http://www.ebi.ac.uk/efo/EFO_0005110 GCST005862 Genome-wide genotyping array 1910 2018-07-12 29738550 de Oliveira Otto MC 2018-05-08 PLoS One www.ncbi.nlm.nih.gov/pubmed/29738550 Genome-wide association meta-analysis of circulating odd-numbered chain saturated fatty acids: Results from the CHARGE Consortium. Circulating odd-numbered chain saturated fatty acid levels (C23:0) 7,582 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 15 fatty acid measurement http://www.ebi.ac.uk/efo/EFO_0005110 GCST005861 Genome-wide genotyping array 7582 2018-09-06 29682794 Szekely E 2018-04-22 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/29682794 Genetic associations with childhood brain growth, defined in two longitudinal cohorts. Basal ganglia growth 581 European ancestry individuals, 31 African American individuals, 8 Asian American individuals, 15 admixed individuals, 80 other ancestries individuals NA Illumina [at least 653030] 2 basal ganglia growth measurement http://www.ebi.ac.uk/efo/EFO_0009325 GCST006220 Genome-wide genotyping array 715 2018-09-06 29682794 Szekely E 2018-04-22 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/29682794 Genetic associations with childhood brain growth, defined in two longitudinal cohorts. White matter growth 581 European ancestry individuals, 31 African American individuals, 8 Asian American individuals 15 admixed individuals, 80 other ancestries individuals NA Illumina [at least 653030] 5 white matter growth measurement http://www.ebi.ac.uk/efo/EFO_0009335 GCST006221 Genome-wide genotyping array 715 2018-09-06 29682794 Szekely E 2018-04-22 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/29682794 Genetic associations with childhood brain growth, defined in two longitudinal cohorts. Cerebellum growth 581 European ancestry individuals, 31 African American individuals, 8 Asian American individuals, 15 admixed individuals, 80 other ancestries individuals NA Illumina [at least 653030] 4 cerebellum growth measurement http://www.ebi.ac.uk/efo/EFO_0009327 GCST006222 Genome-wide genotyping array 715 2018-09-06 29682794 Szekely E 2018-04-22 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/29682794 Genetic associations with childhood brain growth, defined in two longitudinal cohorts. Cerebral cortical growth 581 European ancestry individuals, 31 African American individuals, 8 Asian American individuals, 15 admixed individuals, 80 other ancestries individuals NA Illumina [at least 653030] 5 cerebral cortex growth measurement http://www.ebi.ac.uk/efo/EFO_0009328 GCST006223 Genome-wide genotyping array 715 2018-09-06 29682794 Szekely E 2018-04-22 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/29682794 Genetic associations with childhood brain growth, defined in two longitudinal cohorts. Right lateral prefrontal cortical growth 581 European ancestry individuals, 31 African American individuals, 8 Asian American individuals, 15 admixed individuals, 80 other ancestries individuals NA Illumina [at least 653030] 8 prefrontal cortex growth measurement http://www.ebi.ac.uk/efo/EFO_0009334 GCST006224 Genome-wide genotyping array 715 2018-06-21 29747637 Li JQ 2018-05-10 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/29747637 Genome-wide association study identifies two loci influencing plasma neurofilament light levels. Plasma neurofilament light levels 176 European ancestry mild cognitive impairment cases, 172 European ancestry Alzheimer's disease cases, 179 European ancestry controls NA Illumina [301687] 2 neurofilament light chain measurement http://www.ebi.ac.uk/efo/EFO_0009178 GCST005713 Genome-wide genotyping array 527 2018-07-02 29615537 Kulminski AM 2018-03-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29615537 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. Death 5,974 European ancestry cases, up to 27,457 European ancestry controls NA Affymetrix, Illumina [~ 2500000] (imputed) 0 dead http://purl.obolibrary.org/obo/PATO_0001422 GCST005762 Genome-wide genotyping array 33431 2018-07-02 29615537 Kulminski AM 2018-03-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29615537 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. Body mass index up to 33,431 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 3 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST005769 Genome-wide genotyping array 33431 2018-07-02 29615537 Kulminski AM 2018-03-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29615537 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. C-reactive protein levels up to 33,431 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 0 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST005770 Genome-wide genotyping array 33431 2018-07-02 29615537 Kulminski AM 2018-03-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29615537 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. Creatinine levels up to 33,431 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 0 creatinine measurement http://www.ebi.ac.uk/efo/EFO_0004518 GCST005771 Genome-wide genotyping array 33431 2018-07-02 29615537 Kulminski AM 2018-03-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29615537 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. Diastolic blood pressure up to 33,431 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 3 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST005772 Genome-wide genotyping array 33431 2018-07-02 29615537 Kulminski AM 2018-03-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29615537 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. Lung function (forced vital capacity) up to 33,431 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 0 vital capacity http://www.ebi.ac.uk/efo/EFO_0004312 GCST005773 Genome-wide genotyping array 33431 2018-07-02 29615537 Kulminski AM 2018-03-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29615537 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. Heart rate up to 33,431 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 1 heart rate http://www.ebi.ac.uk/efo/EFO_0004326 GCST005774 Genome-wide genotyping array 33431 2018-07-02 29615537 Kulminski AM 2018-03-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29615537 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. Hematocrit up to 33,431 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 1 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST005775 Genome-wide genotyping array 33431 2018-07-02 29615537 Kulminski AM 2018-03-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29615537 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. High density lipoprotein cholesterol levels up to 33,431 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 8 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST005776 Genome-wide genotyping array 33431 2018-07-02 29615537 Kulminski AM 2018-03-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29615537 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. Systolic blood pressure up to 33,431 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 2 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST005777 Genome-wide genotyping array 33431 2018-07-02 29615537 Kulminski AM 2018-03-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29615537 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. Total cholesterol levels up to 33,431 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 6 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST005781 Genome-wide genotyping array 33431 2018-07-02 29615537 Kulminski AM 2018-03-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29615537 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. Triglyceride levels up to 33,431 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 10 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST005780 Genome-wide genotyping array 33431 2018-07-02 29615537 Kulminski AM 2018-03-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29615537 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. Alzheimer's disease 883 European ancestry cases, up to 32,548 European ancestry controls NA Affymetrix, Illumina [~ 2500000] (imputed) 0 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST005779 Genome-wide genotyping array 33431 2018-07-02 29615537 Kulminski AM 2018-03-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29615537 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. Atrial fibrillation 2,562 European ancestry cases, up to 30,869 European ancestry controls NA Affymetrix, Illumina [~ 2500000] (imputed) 0 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST005778 Genome-wide genotyping array 33431 2018-07-02 29615537 Kulminski AM 2018-03-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29615537 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. Cancer 4,935 European ancestry cases, up to 28,496 European ancestry controls NA Affymetrix, Illumina [~ 2500000] (imputed) 0 cancer http://www.ebi.ac.uk/efo/EFO_0000311 GCST005768 Genome-wide genotyping array 33431 2018-07-02 29615537 Kulminski AM 2018-03-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29615537 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. Coronary heart disease 6,403 European ancestry cases, up to 27,028 European ancestry controls NA Affymetrix, Illumina [~ 2500000] (imputed) 2 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST005767 Genome-wide genotyping array 33431 2018-07-02 29615537 Kulminski AM 2018-03-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29615537 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. Diabetes mellitus 4,315 European ancestry cases, up to 29,116 European ancestry controls NA Affymetrix, Illumina [~ 2500000] (imputed) 1 diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0000400 GCST005766 Genome-wide genotyping array 33431 2018-07-02 29615537 Kulminski AM 2018-03-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29615537 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. Heart failure 3,527 European ancestry cases, up to 29,904 European ancestry controls NA Affymetrix, Illumina [~ 2500000] (imputed) 0 heart failure http://www.ebi.ac.uk/efo/EFO_0003144 GCST005765 Genome-wide genotyping array 33431 2018-07-02 29615537 Kulminski AM 2018-03-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29615537 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. Stroke 2,449 European ancestry cases, up to 30,982 European ancestry controls NA Affymetrix, Illumina [~ 2500000] (imputed) 0 stroke http://www.ebi.ac.uk/efo/EFO_0000712 GCST005764 Genome-wide genotyping array 33431 2018-07-02 29615537 Kulminski AM 2018-03-01 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/29615537 Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. Blood glucose levels up to 33,431 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 2 glucose measurement http://www.ebi.ac.uk/efo/EFO_0004468 GCST005763 Genome-wide genotyping array 33431 2018-09-19 29748315 Pott J 2018-05-01 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/29748315 Genetic Regulation of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Plasma Levels and Its Impact on Atherosclerotic Vascular Disease Phenotypes. Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease 2,022 European ancestry individuals without statin treatment, 1,268 European ancestry individuals with statin treatment NR Affymetrix [9882017] (imputed) 19 PCSK9 protein measurement http://www.ebi.ac.uk/efo/EFO_0006899 GCST006284 Genome-wide genotyping array 3290 2018-06-26 29766673 Fusco JP 2018-05-15 Cancer Med www.ncbi.nlm.nih.gov/pubmed/29766673 Genomic characterization of individuals presenting extreme phenotypes of high and low risk to develop tobacco-induced lung cancer. Non-small cell lung cancer in heavy smokers 47 European ancestry early age cases, 48 European ancestry advanced age controls 78 European ancestry early age cases, 55 European ancestry advanced age controls Illumina [2318553] 0 non-small cell lung carcinoma http://www.ebi.ac.uk/efo/EFO_0003060 GCST005747 Genome-wide genotyping array 95 2018-07-12 29762745 Claus EB 2018-05-12 Neuro Oncol www.ncbi.nlm.nih.gov/pubmed/29762745 Genome-wide association analysis identifies a meningioma risk locus at 11p15.5. Meningioma 1,606 European ancestry cases, 9,823 European ancestry controls 114 European ancestry cases, 406 European ancestry controls, 418 cases, 1,852 controls Affymetrix, Illumina [up to 9213034] (imputed) 1 Meningioma http://www.orpha.net/ORDO/Orphanet_2495 GCST005870 Genome-wide genotyping array 11429 2018-09-06 29769613 Sun X 2018-05-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29769613 Genetic variant for behavioral regulation factor of executive function and its possible brain mechanism in attention deficit hyperactivity disorder. Executive function in ADHD 547 East Asian ancestry cases NA Affymetrix [644166] 1 executive function measurement http://www.ebi.ac.uk/efo/EFO_0009332 GCST006219 Genome-wide genotyping array 547 2019-12-10 31636271 Gallois A 2019-10-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31636271 A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context. Serum metabolite levels (CMS) 6,263 Finnish ancestry men NA Illumina [609262] 588 serum metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005653 GCST009240 Genome-wide genotyping array 6263 2019-12-10 31636271 Gallois A 2019-10-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31636271 A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context. Change in serum metabolite levels 3,351 Finnish ancestry men NA Illumina [609262] 7 serum metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005653 GCST009241 Genome-wide genotyping array 3351 2019-12-10 31636271 Gallois A 2019-10-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31636271 A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context. Change in serum metabolite levels (CMS) 3,351 Finnish ancestry men NA Illumina [609262] 8 serum metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005653 GCST009239 Genome-wide genotyping array 3351 2019-12-10 31636271 Gallois A 2019-10-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31636271 A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context. Serum metabolite levels 6,263 Finnish ancestry men NA Illumina [609262] 474 serum metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005653 GCST009242 Genome-wide genotyping array 6263 2009-03-31 19300482 Pillai SG 2009-03-20 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/19300482 A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci. Chronic obstructive pulmonary disease 823 cases, 810 controls 1,891 European ancestry individuals from 606 families, 389 European ancestry cases, 472 European ancestry controls, 949 individuals from 127 families Illumina [493609] 2 chronic obstructive pulmonary disease http://www.ebi.ac.uk/efo/EFO_0000341 GCST000359 Genome-wide genotyping array 1633 2011-01-14 20801717 Shatunov A 2010-10-01 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/20801717 Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study. Amyotrophic lateral sclerosis 4,857 European ancestry cases, 8,987 European ancestry controls NA Illumina [227475] 4 amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0000253 GCST000820 Genome-wide genotyping array 13844 2008-06-16 18369459 Liu Y 2008-04-04 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/18369459 A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci. Psoriasis 218 European ancestry cases, 519 European ancestry controls 1,153 European ancestry cases, 1,217 European ancestry controls Illumina [305983] 3 psoriasis http://www.ebi.ac.uk/efo/EFO_0000676 GCST000173 Genome-wide genotyping array 737 2009-04-23 19369658 Ikram MA 2009-04-15 N Engl J Med www.ncbi.nlm.nih.gov/pubmed/19369658 Genomewide association studies of stroke. Stroke 1,164 European ancestry ischemic cases, 380 European ancestry cases, 18,058 European ancestry controls 259 African American ancestry ischemic cases, 41 African American ancestry cases, 2,704 African American ancestry controls, 652 European ancestry ischemic cases, 3,613 European ancestry controls Affymetrix, Illumina [2194468] (imputed) 4 stroke http://www.ebi.ac.uk/efo/EFO_0000712 GCST000379 Genome-wide genotyping array 19602 2011-07-13 21572416 Kato N 2011-05-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21572416 Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. Blood pressure 19,608 East Asian ancestry individuals 30,765 East Asian ancestry individuals Affymetrix, Illumina [1700000] (imputed) 9 blood pressure http://www.ebi.ac.uk/efo/EFO_0004325 GCST001072 Genome-wide genotyping array 19608 2011-07-13 21572416 Kato N 2011-05-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21572416 Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. Blood pressure 19,608 East Asian ancestry individuals 30,765 East Asian ancestry individuals Affymetrix, Illumina [1700000] (imputed) 8 blood pressure http://www.ebi.ac.uk/efo/EFO_0004325 GCST001074 Genome-wide genotyping array 19608 2009-03-18 19249006 Xiong DH 2009-02-25 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/19249006 Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups. Bone mineral density 1,000 European ancestry individuals 4,925 European ancestry individuals, 350 Chinese ancestry hip fracture cases, 350 Chinese ancestry hip fracture controls, 2,955 Chinese ancestry individuals, 908 West African ancestry males Affymetrix [379319] 2 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST000347 Genome-wide genotyping array 1000 2009-03-30 19278955 Tregouet DA 2009-03-10 Blood www.ncbi.nlm.nih.gov/pubmed/19278955 Common susceptibility alleles are unlikely to contribute as strongly as the FV and ABO loci to VTE risk: results from a GWAS approach. Venous thromboembolism 419 European ancestry cases, 1,228 European ancestry controls 1,757 European ancestry cases, 1,480 European ancestry controls Illumina [291872] 1 venous thromboembolism http://www.ebi.ac.uk/efo/EFO_0004286 GCST000354 Genome-wide genotyping array 1647 2008-06-27 18488028 Sulem P 2008-05-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18488028 Two newly identified genetic determinants of pigmentation in Europeans. Blue vs. green eyes 5,130 Icelandic individuals 3,330 European ancestry individuals Illumina [316515] 1 eye color http://www.ebi.ac.uk/efo/EFO_0003949 GCST000192 Genome-wide genotyping array 5130 2008-06-27 18488028 Sulem P 2008-05-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18488028 Two newly identified genetic determinants of pigmentation in Europeans. Burning and freckling 5,130 Icelandic individuals 3,330 European ancestry individuals Illumina [316515] 1 freckles, sunburn http://www.ebi.ac.uk/efo/EFO_0003963, http://www.ebi.ac.uk/efo/EFO_0003958 GCST000196 Genome-wide genotyping array 5130 2008-07-01 18488028 Sulem P 2008-05-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18488028 Two newly identified genetic determinants of pigmentation in Europeans. Freckles 5,130 Icelandic individuals 3,330 European ancestry individuals Illumina [316515] 1 freckles http://www.ebi.ac.uk/efo/EFO_0003963 GCST000197 Genome-wide genotyping array 5130 2008-07-01 18488028 Sulem P 2008-05-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18488028 Two newly identified genetic determinants of pigmentation in Europeans. Skin sensitivity to sun 5,130 Icelandic individuals 3,330 European ancestry individuals Illumina [316515] 1 skin sensitivity to sun http://www.ebi.ac.uk/efo/EFO_0004795 GCST000195 Genome-wide genotyping array 5130 2008-06-27 18488028 Sulem P 2008-05-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18488028 Two newly identified genetic determinants of pigmentation in Europeans. Blond vs. brown hair color 5,130 European ancestry individuals 3,330 European ancestry individuals Illumina [316515] 1 hair color http://www.ebi.ac.uk/efo/EFO_0003924 GCST000194 Genome-wide genotyping array 5130 2008-06-27 18488028 Sulem P 2008-05-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18488028 Two newly identified genetic determinants of pigmentation in Europeans. Red vs. non-red hair color 5,130 European ancestry individuals 3,330 European ancestry individuals Illumina [316515] 1 hair color http://www.ebi.ac.uk/efo/EFO_0003924 GCST000193 Genome-wide genotyping array 5130 2011-01-18 21151130 Painter JN 2010-12-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21151130 Genome-wide association study identifies a locus at 7p15.2 associated with endometriosis. Endometriosis 3,194 European ancestry cases, 7,060 European ancestry controls 2,392 European ancestry cases, 2,271 European ancestry controls Illumina [504723] 3 endometriosis http://www.ebi.ac.uk/efo/EFO_0001065 GCST000916 Genome-wide genotyping array 10254 2008-09-08 18439552 Reiner AP 2008-04-24 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/18439552 Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein. C-reactive protein 909 European ancestry individuals 5,106 European ancestry individuals Illumina [317000] 3 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST000179 Genome-wide genotyping array 909 2010-02-28 20081858 Dupuis J 2010-01-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20081858 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Fasting blood insulin 38,238 European ancestry individuals 62,264 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 2 fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004466 GCST000571 Genome-wide genotyping array 38238 2010-02-28 20081858 Dupuis J 2010-01-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20081858 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Fasting blood glucose 46,186 European ancestry individuals 76,558 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 16 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST000568 Genome-wide genotyping array 46186 2018-01-23 20081858 Dupuis J 2010-01-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20081858 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Homeostasis model assessment of insulin resistance 37,037 European ancestry individuals 62,264 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 2 HOMA-IR http://www.ebi.ac.uk/efo/EFO_0004501 GCST005179 Genome-wide genotyping array 37037 2018-01-23 20081858 Dupuis J 2010-01-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20081858 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Homeostasis model assessment of beta-cell function 36,466 European ancestry individuals 62,264 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 10 HOMA-B http://www.ebi.ac.uk/efo/EFO_0004469 GCST005180 Genome-wide genotyping array 36466 2008-06-10 18455228 Richards JB 2008-04-29 Lancet www.ncbi.nlm.nih.gov/pubmed/18455228 Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study. Bone mineral density 2,094 European ancestry female individuals 6,463 European ancestry individuals Illumina [314075] 2 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST000182 Genome-wide genotyping array 2094 2010-03-25 20189936 Okada Y 2010-02-26 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/20189936 A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci. Height 19,633 Japanese ancestry individuals NA Illumina [420885] 25 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST000611 Genome-wide genotyping array 19633 2011-12-20 22095909 Lange CM 2011-11-16 Hepatology www.ncbi.nlm.nih.gov/pubmed/22095909 Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy. Response to hepatitis C treatment 707 European ancestry cases NA NR [NR] 9 chronic hepatitis C virus infection http://www.ebi.ac.uk/efo/EFO_0004220 GCST001325 Genome-wide genotyping array 707 2009-09-30 19754311 Le Clerc S 2009-09-15 J Infect Dis www.ncbi.nlm.nih.gov/pubmed/19754311 Genomewide association study of a rapid progression cohort identifies new susceptibility alleles for AIDS (ANRS Genomewide Association Study 03). AIDS 85 European ancestry cases, 2,049 European ancestry controls NA Illumina [291119] 7 AIDS http://www.ebi.ac.uk/efo/EFO_0000765 GCST000487 Genome-wide genotyping array 2134 2008-06-23 17395743 Hanson RL 2007-04-01 Diabetes www.ncbi.nlm.nih.gov/pubmed/17395743 Identification of PVT1 as a candidate gene for end-stage renal disease in type 2 diabetes using a pooling-based genome-wide single nucleotide polymorphism association study. End-stage renal disease 105 Pima Indian ancestry cases, 102 Pima Indian ancestry controls NA Affymetrix [115352] 1 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST000020 Genome-wide genotyping array 207 2012-09-21 22760553 Adkins DE 2012-07-03 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/22760553 Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D. Response to citalopram treatment 1,392 European ancestry depression cases, 264 African American depression cases, 106 depression cases NA Affymetrix [421789] 17 response to antidepressant http://purl.obolibrary.org/obo/GO_0036276 GCST001591 Genome-wide genotyping array 1762 2008-06-26 18535201 Cooper GM 2008-06-05 Blood www.ncbi.nlm.nih.gov/pubmed/18535201 A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose. Warfarin maintenance dose 181 European ancestry individuals 374 European ancestry individuals Illumina [538629] 3 response to anticoagulant http://purl.obolibrary.org/obo/GO_0061476 GCST000204 Genome-wide genotyping array 181 2010-01-13 20032318 Sleiman PM 2009-12-23 N Engl J Med www.ncbi.nlm.nih.gov/pubmed/20032318 Variants of DENND1B associated with asthma in children. Asthma 793 European ancestry cases, 1,988 European ancestry controls 917 European ancestry cases, 1,546 European ancestry controls, 1,667 African American cases, 2,045 African American controls Illumina [~ 550000] 2 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST000548 Genome-wide genotyping array 2781 2010-09-13 20694148 Zabaneh D 2010-08-04 PLoS One www.ncbi.nlm.nih.gov/pubmed/20694148 A genome-wide association study of the metabolic syndrome in Indian Asian men. Metabolic syndrome 2,554 Indian Asian ancestry individuals 2,240 Indian Asian ancestry individuals Illumina [308011] 18 metabolic syndrome http://www.ebi.ac.uk/efo/EFO_0000195 GCST000753 Genome-wide genotyping array 2554 2010-06-22 20526338 Johnson AD 2010-06-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20526338 Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists. Platelet aggregation Up to 3,991 European ancestry individuals Up to 840 African American individuals Affymetrix, Illumina [~ 2330000] (imputed) 15 platelet aggregation http://purl.obolibrary.org/obo/GO_0070527 GCST000693 Genome-wide genotyping array 3991 2010-03-25 20185149 Athanasiu L 2010-02-23 J Psychiatr Res www.ncbi.nlm.nih.gov/pubmed/20185149 Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort. Schizophrenia 201 European ancestry cases, 305 European ancestry controls 2,663 European ancestry cases, 13,780 European ancestry controls Affymetrix [572888] 3 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST000607 Genome-wide genotyping array 506 2010-01-13 20010835 Hancock DB 2009-12-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20010835 Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Pulmonary function 20,890 European ancestry individuals 16,178 European ancestry individuals Affymetrix, Illumina [2534500] (imputed) 8 pulmonary function measurement http://www.ebi.ac.uk/efo/EFO_0003892 GCST000542 Genome-wide genotyping array 20890 2011-01-19 21160409 Petrovski S 2010-12-14 AIDS www.ncbi.nlm.nih.gov/pubmed/21160409 Common human genetic variants and HIV-1 susceptibility: a genome-wide survey in a homogeneous African population. HIV-1 susceptibility 531 Sub-Saharan African ancestry cases, 848 Sub-Saharan African ancestry controls NA Illumina [~ 800000] 6 HIV-1 infection http://www.ebi.ac.uk/efo/EFO_0000180 GCST000918 Genome-wide genotyping array 1379 2008-06-16 18385676 Amos CI 2008-04-03 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18385676 Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Lung cancer 1,154 European ancestry cases, 1,137 European ancestry controls 2,724 European ancestry cases, 3,694 European ancestry controls Illumina [317498] 3 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST000172 Genome-wide genotyping array 2291 2009-07-12 19578367 Shete S 2009-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19578367 Genome-wide association study identifies five susceptibility loci for glioma. Glioma 1,878 European ancestry cases, 3,670 European ancestry controls 2,545 European ancestry cases, 2,953 European ancestry controls Illumina [454576] 7 central nervous system cancer http://www.ebi.ac.uk/efo/EFO_0000326 GCST000439 Genome-wide genotyping array 5548 2009-07-01 19557197 Heard-Costa NL 2009-06-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/19557197 NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. Waist circumference 31,373 European ancestry individuals 38,641 individuals Affymetrix, Illumina [up to 512349] 7 waist circumference http://www.ebi.ac.uk/efo/EFO_0004342 GCST000427 Genome-wide genotyping array 31373 2009-07-24 19570815 Estrada K 2009-07-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/19570815 A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation. Height 10,074 European ancestry individuals 6,912 European ancestry individuals Affymetrix, Illumina, Perlegen [2228850] (imputed) 5 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST000431 Genome-wide genotyping array 10074 2009-07-01 19557161 Lindgren CM 2009-06-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/19557161 Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. Adiposity 38,580 European ancestry individuals Up to 102,064 European ancestry individuals Affymetrix, Illumina [2573738] (imputed) 4 obesity http://www.ebi.ac.uk/efo/EFO_0001073 GCST000428 Genome-wide genotyping array 38580 2009-02-27 19136949 Carrasquillo MM 2009-01-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19136949 Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease. Alzheimer's disease 844 European ancestry cases, 1,255 European ancestry controls 1,547 European ancestry cases, 1,209 European ancestry controls Illumina [313504] 1 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST000315 Genome-wide genotyping array 2099 2009-07-16 19578364 Bishop DT 2009-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19578364 Genome-wide association study identifies three loci associated with melanoma risk. Melanoma 1,539 European ancestry cases, 3,917 European ancestry controls 2,312 European ancestry cases, 1,867 European ancestry controls Illumina [~ 317000] 5 melanoma http://www.ebi.ac.uk/efo/EFO_0000756 GCST000437 Genome-wide genotyping array 5456 2009-07-13 19578365 Falchi M 2009-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19578365 Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi. Cutaneous nevi 1,524 European ancestry twins 4,107 European ancestry individuals, 3,131 European ancestry cases, 4,276 European ancestry controls Illumina [297108] 2 nevus http://www.ebi.ac.uk/efo/EFO_0000625 GCST000438 Genome-wide genotyping array 1524 2009-09-29 19734902 Harold D 2009-09-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19734902 Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Alzheimer's disease 3,941 European ancestry cases, 7,848 European ancestry controls 2,023 European ancestry cases, 2,340 European ancestry controls Illumina [529205] 3 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST000479 Genome-wide genotyping array 11789 2010-09-10 20668430 Genovese G 2010-07-28 Kidney Int www.ncbi.nlm.nih.gov/pubmed/20668430 A risk allele for focal segmental glomerulosclerosis in African Americans is located within a region containing APOL1 and MYH9. Glomerulosclerosis 56 African American cases, 61 European ancestry cases, 1,759 African American controls, 1,531 European ancestry controls 299 European ancestry cases Illumina [up to 542539] 1 focal segmental glomerulosclerosis http://www.ebi.ac.uk/efo/EFO_0004236 GCST000741 Genome-wide genotyping array 3407 2011-03-28 21348951 Parsa A 2011-02-01 Clin Transl Sci www.ncbi.nlm.nih.gov/pubmed/21348951 Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality. Cardiac hypertrophy 851 Old Order Amish individuals NA Affymetrix [361034] 19 cardiac hypertrophy http://www.ebi.ac.uk/efo/EFO_0002503 GCST000960 Genome-wide genotyping array 851 2011-04-12 21399635 Mells GF 2011-03-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21399635 Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis. Primary biliary cholangitis 1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al) 620 European ancestry cases, 2,514 European ancestry controls Illumina [507467] 21 biliary liver cirrhosis http://www.ebi.ac.uk/efo/EFO_0004267 GCST001010 Genome-wide genotyping array 7003 2009-12-14 19915573 Asano K 2009-11-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19915573 A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population. Ulcerative colitis 376 Japanese ancestry cases, 934 Japanese ancestry controls 376 Japanese ancestry cases, 1,097 Japanese ancestry controls Illumina [513923] 7 ulcerative colitis http://www.ebi.ac.uk/efo/EFO_0000729 GCST000529 Genome-wide genotyping array 1310 2012-02-14 22232737 Shu XO 2012-01-09 Cancer Res www.ncbi.nlm.nih.gov/pubmed/22232737 Novel genetic markers of breast cancer survival identified by a genome-wide association study. Breast cancer (survival) 1,950 Chinese ancestry cases 4,160 Chinese ancestry cases Affymetrix [613031] 3 event free survival time, survival time, breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000482, http://www.ebi.ac.uk/efo/EFO_0000714, http://www.ebi.ac.uk/efo/EFO_0000305 GCST001373 Genome-wide genotyping array 1950 2010-03-24 20228798 Franke A 2010-03-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20228798 Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL). Ulcerative colitis 1,043 European ancestry cases, 1,703 European ancestry controls 2,539 European ancestry cases, 5,428 European ancestry controls Affymetrix [1897764] (imputed) 6 ulcerative colitis http://www.ebi.ac.uk/efo/EFO_0000729 GCST000623 Genome-wide genotyping array 2746 2015-05-20 21221126 Shen Y 2011-01-11 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/21221126 Genome-wide association study of serious blistering skin rash caused by drugs. Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN) up to 72 European ancestry cases, up to 4,251 European ancestry controls NA Illumina [up to 1000000] 4 Stevens-Johnson syndrome, toxic epidermal necrolysis http://www.ebi.ac.uk/efo/EFO_0004276, http://www.ebi.ac.uk/efo/EFO_0004775 GCST000942 Genome-wide genotyping array 4323 2010-04-13 20360844 Arking DE 2010-03-25 PLoS One www.ncbi.nlm.nih.gov/pubmed/20360844 Genome-wide association study identifies GPC5 as a novel genetic locus protective against sudden cardiac arrest. Sudden cardiac arrest 424 European ancestry cases, 226 European ancestry controls 521 cases and 19,090 controls of Black and European ancestry Affymetrix [1966233] (imputed) 0 sudden cardiac arrest http://www.ebi.ac.uk/efo/EFO_0004278 GCST000638 Genome-wide genotyping array 650 2010-05-05 20383146 Kottgen A 2010-04-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20383146 New loci associated with kidney function and chronic kidney disease. Chronic kidney disease Up to 67,093 European ancestry individuals Up to 22,982 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 28 creatinine measurement, cystatin C measurement, chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0004617, http://www.ebi.ac.uk/efo/EFO_0003884 GCST000649 Genome-wide genotyping array 67093 2015-05-23 21300955 Dehghan A 2011-02-07 Circulation www.ncbi.nlm.nih.gov/pubmed/21300955 Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. C-reactive protein levels 63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals 16,540 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 20 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST000965 Genome-wide genotyping array 66185 2011-12-23 22105620 Papassotiropoulos A 2011-11-22 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/22105620 A genome-wide survey and functional brain imaging study identify CTNNBL1 as a memory-related gene. Memory performance 1,073 European ancestry individuals 524 individuals Affymetrix [582514] 0 memory performance http://www.ebi.ac.uk/efo/EFO_0004874 GCST001327 Genome-wide genotyping array 1073 2008-06-16 17522711 Lencz T 2007-03-20 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/17522711 Converging evidence for a pseudoautosomal cytokine receptor gene locus in schizophrenia. Schizophrenia 178 European ancestry cases, 144 European ancestry controls NA Affymetrix [439511] 1 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST000016 Genome-wide genotyping array 322 2009-10-16 19801982 Rivadeneira F 2009-10-04 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19801982 Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Bone mineral density (hip) 19,195 European ancestry individuals NA Affymetrix, Illumina [2543686] (imputed) 13 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST000495 Genome-wide genotyping array 19195 2009-10-16 19801982 Rivadeneira F 2009-10-04 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19801982 Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Bone mineral density (spine) 19,195 European ancestry individuals NA Affymetrix, Illumina [2543686] (imputed) 16 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST000494 Genome-wide genotyping array 19195 2010-01-19 20041166 Fellay J 2009-12-24 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/20041166 Common genetic variation and the control of HIV-1 in humans. HIV-1 control 2,362 European ancestry cases NA Illumina [NR] 42 HIV-1 infection http://www.ebi.ac.uk/efo/EFO_0000180 GCST000549 Genome-wide genotyping array 2362 2010-11-17 20935629 Heid IM 2010-10-10 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20935629 Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Waist-hip ratio Up to 77,167 European ancestry individuals Up to 113,636 European ancestry individuals Affymetrix, Illumina, Perlegen [up to 2850269] (imputed) 16 waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0004343 GCST000829 Genome-wide genotyping array 77167 2010-09-07 20732626 Mick E 2010-05-14 J Am Acad Child Adolesc Psychiatry www.ncbi.nlm.nih.gov/pubmed/20732626 Family-based genome-wide association scan of attention-deficit/hyperactivity disorder. Attention deficit hyperactivity disorder 735 trios from 732 families NA Illumina [835136] 10 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST000684 Genome-wide genotyping array 1467 2015-04-20 21292315 Nalls MA 2011-02-01 Lancet www.ncbi.nlm.nih.gov/pubmed/21292315 Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. Parkinson's disease 5,333 European ancestry cases, 12,019 European ancestry controls 7,053 cases, 9,007 controls Illumina [7689524] (imputed) 11 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST000959 Genome-wide genotyping array 17352 2008-09-17 18391952 Weedon MN 2008-04-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18391952 Genome-wide association analysis identifies 20 loci that influence adult height. Height 13,665 European ancestry individuals 16,482 European ancestry individuals Affymetrix [402951] 20 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST000174 Genome-wide genotyping array 13665 2010-03-06 20139977 Codd V 2010-02-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20139977 Common variants near TERC are associated with mean telomere length. Telomere length 2,917 European ancestry individuals 9,492 European ancestry individuals Affymetrix [405649] 1 telomere length http://www.ebi.ac.uk/efo/EFO_0004505 GCST000586 Genome-wide genotyping array 2917 2010-09-10 20668459 Kim HN 2010-07-29 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/20668459 Genetic variants that affect length/height in infancy/early childhood in Vietnamese-Korean families. Height 518 Vietnamese-Korean ancestry individuals from 165 families NA Illumina [269888] 1 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST000744 Genome-wide genotyping array 683 2015-04-24 21239051 Reilly MP 2011-01-14 Lancet www.ncbi.nlm.nih.gov/pubmed/21239051 Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies. Coronary artery disease 1,808 European ancestry cases, 915 European ancestry controls 10,585 European ancestry cases, 6,468 European ancestry controls Affymetrix, Illumina [> 2400000] (imputed) 3 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST000945 Genome-wide genotyping array 2723 2015-04-24 21239051 Reilly MP 2011-01-14 Lancet www.ncbi.nlm.nih.gov/pubmed/21239051 Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies. Myocardial infarction in coronary artery disease 4,572 European ancestry cases, 2,739 European ancestry controls 1,211 European ancestry cases, 905 European ancestry controls Affymetrix, Illumina [up to 2400000] (imputed) 1 myocardial infarction http://www.ebi.ac.uk/efo/EFO_0000612 GCST000946 Genome-wide genotyping array 7311 2010-03-29 20201924 Edenberg HJ 2010-03-01 Alcohol Clin Exp Res www.ncbi.nlm.nih.gov/pubmed/20201924 Genome-wide association study of alcohol dependence implicates a region on chromosome 11. Alcohol dependence 847 European ancestry cases, 552 European ancestry controls, 345 African American cases, 140 African American controls 262 families Illumina [up to 941298] 0 alcohol dependence http://www.ebi.ac.uk/efo/EFO_0003829 GCST000617 Genome-wide genotyping array 1884 2010-09-02 20602913 Duffy DL 2010-07-17 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/20602913 IRF4 variants have age-specific effects on nevus count and predispose to melanoma. Nevus count 1,810 European ancestry twins 1,470 European ancestry parents of twins, 2,247 European ancestry twins, 485 European ancestry individuals, 925 European ancestry melanoma cases Illumina [529721] 0 nevus count http://www.ebi.ac.uk/efo/EFO_0004632 GCST000732 Genome-wide genotyping array 1810 2010-10-07 20858683 Soranzo N 2010-09-21 Diabetes www.ncbi.nlm.nih.gov/pubmed/20858683 Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Glycated hemoglobin levels up to 46,368 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 11 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST000803 Genome-wide genotyping array 46368 2010-09-21 20705733 O'Seaghdha CM 2010-08-12 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/20705733 Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels. Calcium levels 20,611 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 10 calcium measurement http://www.ebi.ac.uk/efo/EFO_0004838 GCST000769 Genome-wide genotyping array 20611 2011-01-15 21149283 Oexle K 2010-12-10 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21149283 Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels. Iron status biomarkers Up to 6,616 individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 5 iron biomarker measurement http://www.ebi.ac.uk/efo/EFO_0004461 GCST000913 Genome-wide genotyping array 6616 2010-02-02 20066004 Chung CM 2010-01-12 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/20066004 A genome-wide association study identifies new loci for ACE activity: potential implications for response to ACE inhibitor. Angiotensin-converting enzyme activity 400 Han Chinese ancestry hypertensive cases 623 Han Chinese ancestry hypertensive cases Illumina [~ 550000] 2 angiotensin converting enzyme activity measurement http://www.ebi.ac.uk/efo/EFO_0004463 GCST000565 Genome-wide genotyping array 400 2009-12-11 19915572 Barrett JC 2009-11-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19915572 Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Ulcerative colitis 2,361 European ancestry cases, 5,417 European ancestry controls 2,321 European ancestry cases, 4,818 European ancestry controls Affymetrix [NR] 13 ulcerative colitis http://www.ebi.ac.uk/efo/EFO_0000729 GCST000527 Genome-wide genotyping array 7778 2010-10-05 20833655 Cha PC 2010-09-10 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/20833655 Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese. Warfarin maintenance dose 807 Japanese ancestry low dose individuals, 701 Japanese ancestry high dose individuals 444 Japanese ancestry individuals Illumina [485227] 5 response to anticoagulant http://purl.obolibrary.org/obo/GO_0061476 GCST000792 Genome-wide genotyping array 1508 2010-10-14 20885792 Naj AC 2010-09-23 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/20885792 Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities. Alzheimer's disease (late onset) 931 cases, 1,104 controls 1,338 cases, 2,003 controls Illumina [483399] 4 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST000808 Genome-wide genotyping array 2035 2010-04-06 20195266 Adkins DE 2010-03-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/20195266 Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs. Response to antipsychotic treatment 421 European ancestry, 214 African American, and 103 cases NA Affymetrix [492900] 37 response to antipsychotic drug http://purl.obolibrary.org/obo/GO_0097332 GCST000618 Genome-wide genotyping array 738 2011-01-27 21216876 Sharma S 2011-01-07 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21216876 Genome-wide association studies of adolescent idiopathic scoliosis suggest candidate susceptibility genes. Adolescent idiopathic scoliosis 1,113 European, African, Oceania, Hispanic and other ancestry individuals from 418 families 562 European ancestry cases, 666 European ancestry controls, 137 cases, 2,126 controls Illumina [326498] 1 scoliosis http://www.ebi.ac.uk/efo/EFO_0004273 GCST000938 Genome-wide genotyping array 1531 2012-04-28 22479309 Boraska V 2012-03-29 PLoS One www.ncbi.nlm.nih.gov/pubmed/22479309 Genome-wide association study to identify common variants associated with brachial circumference: a meta-analysis of 14 cohorts. Brachial circumference 18,753 European ancestry individuals 3,623 European ancestry individuals Affymetrix, Illumina [2238430] (imputed) 1 brachial circumference http://www.ebi.ac.uk/efo/EFO_0004589 GCST001462 Genome-wide genotyping array 18753 2013-09-05 23626673 Matullo G 2013-04-23 PLoS One www.ncbi.nlm.nih.gov/pubmed/23626673 Genetic variants associated with increased risk of malignant pleural mesothelioma: a genome-wide association study. Malignant pleural mesothelioma 392 European ancestry cases, 367 European ancestry controls 428 European ancestry cases, 1,269 European ancestry controls Illumina [5000000] (imputed) 0 malignant pleural mesothelioma http://www.ebi.ac.uk/efo/EFO_0000770 GCST001978 Genome-wide genotyping array 759 2012-09-11 22764253 Thier S 2012-07-03 Neurology www.ncbi.nlm.nih.gov/pubmed/22764253 Polymorphisms in the glial glutamate transporter SLC1A2 are associated with essential tremor. Essential tremor 436 European ancestry cases, 928 European ancestry controls 554 European ancestry cases, 609 European ancestry controls Affymetrix [620077] 1 essential tremor http://www.ebi.ac.uk/efo/EFO_0003108 GCST001590 Genome-wide genotyping array 1364 2012-09-18 22797727 Okada Y 2012-07-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22797727 Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Renal function-related traits (BUN) 39,717 East Asian ancestry individuals 17,461 East Asian ancestry individuals Affymetrix, Illumina [2281523] (imputed) 15 renal system measurement, blood urea nitrogen measurement http://www.ebi.ac.uk/efo/EFO_0004742, http://www.ebi.ac.uk/efo/EFO_0004741 GCST001610 Genome-wide genotyping array 39717 2012-09-18 22797727 Okada Y 2012-07-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22797727 Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Renal function-related traits (sCR) 42,257 East Asian, South Asian, and South East Asian ancestry individuals 19,662 East Asian ancestry individuals Affymetrix, Illumina [2353587] (imputed) 9 renal system measurement http://www.ebi.ac.uk/efo/EFO_0004742 GCST001606 Genome-wide genotyping array 42257 2012-09-18 22797727 Okada Y 2012-07-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22797727 Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Renal function-related traits (eGRFcrea) 42,451 East Asian, South Asian, and South East Asian ancestry individuals 19,636 East Asian ancestry individuals Affymetrix, Illumina [2353587] (imputed) 10 renal system measurement http://www.ebi.ac.uk/efo/EFO_0004742 GCST001607 Genome-wide genotyping array 42451 2012-09-18 22797727 Okada Y 2012-07-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22797727 Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Renal function-related traits (urea) 21,417 East Asian ancestry individuals 11,657 East Asian ancestry individuals Affymetrix, Illumina [2278301] (imputed) 4 renal system measurement, uric acid measurement http://www.ebi.ac.uk/efo/EFO_0004742, http://www.ebi.ac.uk/efo/EFO_0004761 GCST001608 Genome-wide genotyping array 21417 2012-08-14 22726844 Kim JW 2012-06-20 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/22726844 A common variant in SLC8A1 is associated with the duration of the electrocardiographic QT interval. QT interval 6,805 Korean ancestry individuals 7,373 East Asian ancestry individuals Affymetrix [352228] 3 QT interval http://www.ebi.ac.uk/efo/EFO_0004682 GCST001580 Genome-wide genotyping array 6805 2013-06-21 23470693 Zeng Z 2013-03-07 J Dent Res www.ncbi.nlm.nih.gov/pubmed/23470693 Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition. Pit-and-Fissure caries 996 European ancestry individuals NA Illumina [1200000] (imputed) 8 pit and fissure surface dental caries http://www.ebi.ac.uk/efo/EFO_0006338 GCST001897 Genome-wide genotyping array 996 2013-06-21 23470693 Zeng Z 2013-03-07 J Dent Res www.ncbi.nlm.nih.gov/pubmed/23470693 Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition. Smooth-surface caries 982 European ancestry individuals NA Illumina [1200000] (imputed) 11 smooth surface dental caries http://www.ebi.ac.uk/efo/EFO_0006339 GCST001896 Genome-wide genotyping array 982 2010-09-02 20639392 Eijgelsheim M 2010-07-16 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/20639392 Genome-wide association analysis identifies multiple loci related to resting heart rate. Resting heart rate 38,991 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 10 resting heart rate http://www.ebi.ac.uk/efo/EFO_0004351 GCST000731 Genome-wide genotyping array 38991 2013-06-20 23472165 Albertsen HM 2013-03-05 PLoS One www.ncbi.nlm.nih.gov/pubmed/23472165 Genome-wide association study link novel loci to endometriosis. Endometriosis 1,514 European ancestry cases, 12,660 European ancestry controls 505 European ancestry cases, 1,811 European ancestry controls Illumina [580699] 15 endometriosis http://www.ebi.ac.uk/efo/EFO_0001065 GCST001894 Genome-wide genotyping array 14174 2013-05-09 23377640 GENDEP Investigators 2013-02-01 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/23377640 Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. Major depressive disorder Up to 2,256 European ancestry cases NA Affymetrix, Illumina [1200000] (imputed) 49 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST001850 Genome-wide genotyping array 2256 2013-02-27 23266558 Yamazaki K 2012-12-21 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/23266558 A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population. Crohn's disease 372 Japanese ancestry cases,3,389 Japanese ancestry controls Up to 1,151 Japanese ancestry cases, up to 15,800 Japanese ancestry controls Illumina [4929034] (imputed) 11 Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000384 GCST001785 Genome-wide genotyping array 3761 2012-02-28 22286219 Kettunen J 2012-01-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22286219 Genome-wide association study identifies multiple loci influencing human serum metabolite levels. Metabolite levels 8,330 European ancestry individuals NA Illumina [~ 7700000] (imputed) 13 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST001391 Genome-wide genotyping array 8330 2012-02-28 22286219 Kettunen J 2012-01-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22286219 Genome-wide association study identifies multiple loci influencing human serum metabolite levels. Lipid metabolism phenotypes 8,330 European ancestry individuals NA Illumina [~ 7700000] (imputed) 18 lipid measurement http://www.ebi.ac.uk/efo/EFO_0004529 GCST001392 Genome-wide genotyping array 8330 2008-09-03 18758461 Di Bernardo MC 2008-08-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18758461 A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia. Chronic lymphocytic leukemia 505 European ancestry cases, 1,438 European ancestry controls 1,024 European ancestry cases, 1,677 European ancestry controls Illumina [345665] 6 chronic lymphocytic leukemia http://www.ebi.ac.uk/efo/EFO_0000095 GCST000224 Genome-wide genotyping array 1943 2008-09-03 18591461 Turner ST 2008-06-30 Hypertension www.ncbi.nlm.nih.gov/pubmed/18591461 Genomic association analysis suggests chromosome 12 locus influencing antihypertensive response to thiazide diuretic. Response to diuretic therapy 97 African American good response individuals, 97 African American poor response individuals, 98 European ancestry good response individuals, 97 European ancestry poor response individuals NA Affymetrix [up to 102334] 1 response to diuretic http://purl.obolibrary.org/obo/GO_0036270 GCST000208 Genome-wide genotyping array 389 2009-09-28 19721433 McClay JL 2009-09-01 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/19721433 Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics. Response to antipsychotic treatment 494 European ancestry cases, 244 African American and other ancestry cases NA Affymetrix, Perlegen [492900] 9 response to antipsychotic drug http://purl.obolibrary.org/obo/GO_0097332 GCST000473 Genome-wide genotyping array 738 2012-01-06 22159054 Logue MW 2011-12-01 Arch Neurol www.ncbi.nlm.nih.gov/pubmed/22159054 A comprehensive genetic association study of Alzheimer disease in African Americans. Alzheimer's disease 513 African American cases, 496 African American controls NA Illumina [2505093] (imputed) 11 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST001342 Genome-wide genotyping array 1009 2012-11-08 19734545 Need AC 2009-09-04 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/19734545 A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB. Cognitive performance Up to 1,295 individuals NA Illumina [475971] 59 neuropsychological test http://www.ebi.ac.uk/efo/EFO_0003926 GCST000477 Genome-wide genotyping array 1295 2010-01-21 20060832 Rauch A 2010-01-07 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/20060832 Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study. Chronic hepatitis C infection 1,015 European ancestry chronic HCV carriers, 347 European ancestry spontaneously cleared HCV individuals NA Illumina [~ 500000] 1 chronic hepatitis C virus infection http://www.ebi.ac.uk/efo/EFO_0004220 GCST000557 Genome-wide genotyping array 1362 2011-06-23 21627779 Antunez C 2011-05-31 Genome Med www.ncbi.nlm.nih.gov/pubmed/21627779 The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease. Alzheimer's disease 319 European ancestry cases, 769 European ancestry controls, 2,690 cases, 2,237 controls 4,982 European ancestry cases, 7,961 European ancestry controls, 2,190 cases, 3,374 controls Affymetrix, Illumina [696707] (imputed) 5 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST001087 Genome-wide genotyping array 6015 2008-06-22 18464913 Melzer D 2008-05-09 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/18464913 A genome-wide association study identifies protein quantitative trait loci (pQTLs). Protein quantitative trait loci 1,200 European ancestry individuals up to 4,590 European ancestry individuals Illumina [496032] 49 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST000189 Genome-wide genotyping array 1200 2009-06-14 19465909 Jallow M 2009-05-24 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19465909 Genome-wide and fine-resolution association analysis of malaria in West Africa. Malaria 958 Gambian ancestry cases, 1,382 Gambian ancestry controls 1,087 Gambian ancestry cases, 2,376 Gambian ancestry controls Affymetrix [402814] 3 malaria http://www.ebi.ac.uk/efo/EFO_0001068 GCST000410 Genome-wide genotyping array 2340 2008-08-07 18615156 Liu C 2008-07-10 Mol Med www.ncbi.nlm.nih.gov/pubmed/18615156 Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis. Response to TNF antagonist treatment 89 European ancestry cases NA Illumina [283348] 8 response to TNF antagonist http://www.ebi.ac.uk/efo/EFO_0004653 GCST000211 Genome-wide genotyping array 89 2008-09-25 18794853 Raychaudhuri S 2008-09-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18794853 Common variants at CD40 and other loci confer risk of rheumatoid arthritis. Rheumatoid arthritis 3,393 European ancestry cases, 12,460 European ancestry controls 3,929 European ancestry cases, 5,807 European ancestry controls Affymetrix, Illumina [at least 315971] (imputed) 9 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST000232 Genome-wide genotyping array 15853 2008-12-09 18951430 Anney RJ 2008-10-24 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/18951430 Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. Attention deficit hyperactivity disorder and conduct disorder 938 European ancestry trios NA Perlegen [378332] 26 attention deficit hyperactivity disorder, conduct disorder http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0004216 GCST000253 Genome-wide genotyping array 938 2010-09-22 20711176 Nakashima M 2010-08-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20711176 A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population. Keloid 178 Japanese ancestry cases, 906 Japanese ancestry controls 621 Japanese ancestry cases, 2,271 Japanese ancestry controls Illumina [452038] 4 Keloid http://www.ebi.ac.uk/efo/EFO_0004212 GCST000773 Genome-wide genotyping array 1084 2012-02-09 22247754 Murray SS 2012-01-11 PLoS One www.ncbi.nlm.nih.gov/pubmed/22247754 Genome-wide association of implantable cardioverter-defibrillator activation with life-threatening arrhythmias. Life threatening arrhythmia 607 European ancestry cases, 297 European ancestry controls NA Illumina [NR] (imputed) 2 cardiac arrhythmia http://www.ebi.ac.uk/efo/EFO_0004269 GCST001376 Genome-wide genotyping array 904 2011-01-18 20953190 Strange A 2010-10-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20953190 A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Psoriasis 2,178 European ancestry cases, 5,175 European ancestry controls 3,174 European ancestry cases, 5,464 European ancestry controls Illumina [535475] 17 psoriasis http://www.ebi.ac.uk/efo/EFO_0000676 GCST000833 Genome-wide genotyping array 7353 2013-11-01 23583980 Fingerlin TE 2013-04-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23583980 Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis. Interstitial lung disease 1,161 European ancestry cases, 4,683 European ancestry controls 876 European ancestry cases, 1,890 European ancestry controls Illumina [439828] 16 interstitial lung disease http://www.ebi.ac.uk/efo/EFO_0004244 GCST001968 Genome-wide genotyping array 5844 2011-06-25 21659334 Tanaka Y 2011-06-09 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21659334 Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C. Response to hepatitis C treatment 303 Japanese ancestry cases 391 Japanese ancestry cases Affymetrix [595052] 4 chronic hepatitis C virus infection http://www.ebi.ac.uk/efo/EFO_0004220 GCST001094 Genome-wide genotyping array 303 2014-03-27 24068962 O'Seaghdha CM 2013-09-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/24068962 Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations. Calcium levels 39,400 European ancestry individuals Up to 21,679 European ancestry individuals Affymetrix, Illumina [2500000] (imputed) 13 calcium measurement http://www.ebi.ac.uk/efo/EFO_0004838 GCST002201 Genome-wide genotyping array 39400 2013-12-03 23725790 Renteria ME 2013-06-03 Twin Res Hum Genet www.ncbi.nlm.nih.gov/pubmed/23725790 GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association. DNA methylation (parent-of-origin) 1,024 European ancestry individuals NA Illumina [515966] 7 DNA methylation http://purl.obolibrary.org/obo/GO_0006306 GCST002057 Genome-wide genotyping array 1024 2013-12-03 23725790 Renteria ME 2013-06-03 Twin Res Hum Genet www.ncbi.nlm.nih.gov/pubmed/23725790 GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association. DNA methylation (variation) 256 European ancestry individuals 384 European ancestry individuals Illumina [515966] 19 DNA methylation http://purl.obolibrary.org/obo/GO_0006306 GCST002058 Genome-wide genotyping array 256 2013-03-20 23263863 Li J 2012-12-20 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23263863 GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. Mean corpuscular hemoglobin 7,943 African American children, 6,234 European ancestry children NA Illumina [544917] 10 mean corpuscular hemoglobin http://www.ebi.ac.uk/efo/EFO_0004527 GCST001780 Genome-wide genotyping array 14177 2013-03-15 23263863 Li J 2012-12-20 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23263863 GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. Hematology traits 7,943 African American children, 6,234 European ancestry children NA Illumina [544917] 12 hemoglobin measurement, leukocyte count, erythrocyte count, hematocrit http://www.ebi.ac.uk/efo/EFO_0004509, http://www.ebi.ac.uk/efo/EFO_0004308, http://www.ebi.ac.uk/efo/EFO_0004305, http://www.ebi.ac.uk/efo/EFO_0004348 GCST001779 Genome-wide genotyping array 14177 2013-03-15 23263863 Li J 2012-12-20 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23263863 GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. Mean corpuscular hemoglobin concentration 7,943 African American children, 6,234 European ancestry children NA Illumina [544917] 6 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST001782 Genome-wide genotyping array 14177 2013-03-15 23263863 Li J 2012-12-20 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23263863 GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. Mean corpuscular volume 7,943 African American children, 6,234 European ancestry children NA Illumina [544917] 10 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST001781 Genome-wide genotyping array 14177 2013-03-15 23263863 Li J 2012-12-20 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23263863 GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. Platelet count 7,943 African American children, 6,234 European ancestry children NA Illumina [544917] 8 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST001783 Genome-wide genotyping array 14177 2013-09-04 20139978 Kamatani Y 2010-02-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20139978 Genome-wide association study of hematological and biochemical traits in a Japanese population. Red blood cell count 14,392 Japanese ancestry individuals NA Illumina [561583] 8 erythrocyte count http://www.ebi.ac.uk/efo/EFO_0004305 GCST000588 Genome-wide genotyping array 14392 2013-09-04 20139978 Kamatani Y 2010-02-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20139978 Genome-wide association study of hematological and biochemical traits in a Japanese population. White blood cell count 14,677 Japanese ancestry individuals NA Illumina [561583] 5 leukocyte count http://www.ebi.ac.uk/efo/EFO_0004308 GCST000589 Genome-wide genotyping array 14677 2013-09-04 20139978 Kamatani Y 2010-02-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20139978 Genome-wide association study of hematological and biochemical traits in a Japanese population. Mean corpuscular hemoglobin concentration 14,377 Japanese ancestry individuals NA Illumina [561583] 7 hemoglobin measurement, mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004509, http://www.ebi.ac.uk/efo/EFO_0004528 GCST000582 Genome-wide genotyping array 14377 2013-09-04 20139978 Kamatani Y 2010-02-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20139978 Genome-wide association study of hematological and biochemical traits in a Japanese population. Triglycerides 8,993 Japanese ancestry individuals NA Illumina [561583] 6 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST000584 Genome-wide genotyping array 8993 2013-09-04 20139978 Kamatani Y 2010-02-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20139978 Genome-wide association study of hematological and biochemical traits in a Japanese population. Platelet count 14,806 Japanese ancestry individuals NA Illumina [561583] 7 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST000580 Genome-wide genotyping array 14806 2013-09-04 20139978 Kamatani Y 2010-02-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20139978 Genome-wide association study of hematological and biochemical traits in a Japanese population. Mean corpuscular hemoglobin Up to 14,362 Japanese ancestry individuals NA Illumina [561583] 15 hemoglobin measurement, mean corpuscular hemoglobin http://www.ebi.ac.uk/efo/EFO_0004509, http://www.ebi.ac.uk/efo/EFO_0004527 GCST000587 Genome-wide genotyping array 14362 2013-09-04 20139978 Kamatani Y 2010-02-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20139978 Genome-wide association study of hematological and biochemical traits in a Japanese population. Urate levels 8,868 Japanese ancestry individuals NA Illumina [561583] 5 urate measurement http://www.ebi.ac.uk/efo/EFO_0004531 GCST000581 Genome-wide genotyping array 8868 2013-11-05 20139978 Kamatani Y 2010-02-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20139978 Genome-wide association study of hematological and biochemical traits in a Japanese population. Hematological and biochemical traits Up to 14,402 Japanese individuals NA Illumina [561583] 29 serum albumin measurement, aspartate aminotransferase measurement, alkaline phosphatase measurement, hemoglobin measurement, creatinine measurement, serum alanine aminotransferase measurement, serum gamma-glutamyl transferase measurement, hematocrit, creatine kinase measurement, protein measurement, uric acid measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004535, http://www.ebi.ac.uk/efo/EFO_0004736, http://www.ebi.ac.uk/efo/EFO_0004533, http://www.ebi.ac.uk/efo/EFO_0004509, http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0004735, http://www.ebi.ac.uk/efo/EFO_0004532, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0004534, http://www.ebi.ac.uk/efo/EFO_0004747, http://www.ebi.ac.uk/efo/EFO_0004761, http://www.ebi.ac.uk/efo/EFO_0004612 GCST000583 Genome-wide genotyping array 14402 2013-09-04 20139978 Kamatani Y 2010-02-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20139978 Genome-wide association study of hematological and biochemical traits in a Japanese population. Mean corpuscular volume 14,364 Japanese ancestry individuals NA Illumina [561583] 17 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST000585 Genome-wide genotyping array 14364 2011-07-13 21700618 Nan H 2011-06-23 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21700618 Genome-wide association study identifies novel alleles associated with risk of cutaneous basal cell carcinoma and squamous cell carcinoma. Basal cell carcinoma 2,045 European ancestry cases, 6,013 European ancestry controls 1,426 cases, 4,845 controls Affymetrix, Illumina [2318094] (imputed) 3 basal cell carcinoma http://www.ebi.ac.uk/efo/EFO_0004193 GCST001124 Genome-wide genotyping array 8058 2011-01-06 21088011 Erdmann J 2010-11-18 Eur Heart J www.ncbi.nlm.nih.gov/pubmed/21088011 Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23. Coronary heart disease 1,157 European ancestry cases, 1,748 European ancestry controls 7,887 European ancestry cases, 8,244 European ancestry controls Affymetrix [254558] 1 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST000875 Genome-wide genotyping array 2905 2015-05-12 21696813 Schauberger EM 2011-06-20 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/21696813 Identification of ATPAF1 as a novel candidate gene for asthma in children. Asthma (childhood onset) 112 European ancestry child cases, 165 European ancestry child controls 1,481 European ancestry individuals from 341 families, 429 European ancestry trios, 52 African American trios, 1,231 Hispanic trios, 46 trios, 6,475 European ancestry controls Affymetrix [98921] 0 childhood onset asthma http://www.ebi.ac.uk/efo/EFO_0004591 GCST001117 Genome-wide genotyping array 277 2011-07-13 21700879 Qi L 2011-06-23 Diabetes www.ncbi.nlm.nih.gov/pubmed/21700879 Novel locus FER is associated with serum HMW adiponectin levels. Adiponectin levels 1,591 European ancestry female individuals 626 European ancestry individuals from 235 families Affymetrix [2543887] (imputed) 5 adiponectin measurement http://www.ebi.ac.uk/efo/EFO_0004502 GCST001122 Genome-wide genotyping array 1591 2012-11-02 20889312 Wang KS 2010-10-01 Schizophr Res www.ncbi.nlm.nih.gov/pubmed/20889312 A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder. Bipolar disorder and schizophrenia 651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls NA Affymetrix [722112] 103 mental or behavioural disorder http://www.ebi.ac.uk/efo/EFO_0000677 GCST000821 Genome-wide genotyping array 4234 2012-03-09 22293688 Huang J 2012-02-01 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/22293688 1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data. Type 1 diabetes 16,179 European ancestry individuals NA NR [6233112] (imputed) 2 type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001359 GCST001394 Genome-wide genotyping array 16179 2012-03-10 22293688 Huang J 2012-02-01 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/22293688 1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data. Type 2 diabetes 16,179 European ancestry individuals NA NR [6233112] (imputed) 1 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST001397 Genome-wide genotyping array 16179 2012-03-10 22293688 Huang J 2012-02-01 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/22293688 1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data. Crohn's disease 16,179 European ancestry individuals NA NR [6233112] (imputed) 1 Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000384 GCST001396 Genome-wide genotyping array 16179 2015-04-14 21699788 Okada Y 2011-06-20 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/21699788 HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease. Ulcerative colitis or Crohn's disease 372 Japanese ancestry Crohn's disease cases, 372 Japanese ancestry ulcerative colitis cases 607 Japanese ancestry Crohn's disease cases, 376 Japanese ancestry ulcerative colitis cases Illumina [461368] 2 ulcerative colitis, Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000729, http://www.ebi.ac.uk/efo/EFO_0000384 GCST001118 Genome-wide genotyping array 744 2012-09-26 22837378 Wilk JB 2012-07-26 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/22837378 Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. Airflow obstruction up to 3,368 European ancestry cases, up to 29,507 European ancestry controls 331 European ancestry cases, 2,550 European ancestry controls Affymetrix, Illumina [up to 2500000] (imputed) 30 pulmonary function measurement http://www.ebi.ac.uk/efo/EFO_0003892 GCST001621 Genome-wide genotyping array 32875 2013-09-12 23563607 Berndt SI 2013-04-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23563607 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Obesity 93,015 European ancestry overweight individuals, 32,858 European ancestry class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls 65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls Affymetrix, Illumina [~ 2800000] (imputed) 66 anthropometric measurement http://www.ebi.ac.uk/efo/EFO_0004302 GCST001953 Genome-wide genotyping array 204498 2013-09-12 23563607 Berndt SI 2013-04-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23563607 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Waist-hip ratio 4,774 European ancestry high waist-to-hip ratio individuals, 5,481 European ancestry low waist-to-hip ratio individuals 3,351 European ancestry high waist-to-hip ratio individuals, 3,352 European ancestry low waist-to-hip ratio individuals Affymetrix, Illumina [~ 2800000] (imputed) 4 anthropometric measurement http://www.ebi.ac.uk/efo/EFO_0004302 GCST001954 Genome-wide genotyping array 10255 2013-09-12 23563607 Berndt SI 2013-04-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23563607 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Body mass index 7,962 European ancestry high body mass index individuals, 8,106 European ancestry low body mass index individuals 4,900 European ancestry high body mass index individuals, 4,891 European ancestry low body mass index individuals Affymetrix, Illumina [~ 2800000] (imputed) 10 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST001955 Genome-wide genotyping array 16068 2013-09-12 23563607 Berndt SI 2013-04-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23563607 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Height 8,097 European ancestry tall individuals, 8,099 European ancestry short individuals 4,872 European ancestry tall individuals, 4,831 European ancestry short individuals Affymetrix, Illumina [~ 2800000] (imputed) 86 anthropometric measurement http://www.ebi.ac.uk/efo/EFO_0004302 GCST001956 Genome-wide genotyping array 16196 2015-05-06 22889921 Stewart SE 2012-08-14 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/22889921 Genome-wide association study of obsessive-compulsive disorder. Obsessive-compulsive disorder 1,279 European ancestry cases, 5,139 European ancestry controls, 299 European ancestry trios, 93 South African Afrikaner ancestry cases, 158 South African Afrikaner ancestry controls, 93 Ashkenazi Jewish cases, 260 Ashkenazi Jewish controls, 101 Hispanic and unknown ancestry trios NA Illumina [479067] 3 obsessive-compulsive disorder http://www.ebi.ac.uk/efo/EFO_0004242 GCST001636 Genome-wide genotyping array 7422 2014-02-25 24144296 Cheng CY 2013-08-08 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/24144296 Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. Axial length 12,531 European ancestry individuals 8,216 Asian ancestry individuals Illumina [2500000] (imputed) 21 axial length measurement http://www.ebi.ac.uk/efo/EFO_0005318 GCST002115 Genome-wide genotyping array 12531 2014-05-13 24185611 Cook MB 2013-11-02 Hum Genet www.ncbi.nlm.nih.gov/pubmed/24185611 A genome-wide association study of prostate cancer in West African men. Prostate cancer 474 West African ancestry cases, 458 West African ancestry controls 5,096 African American cases, 4,972 African American controls Illumina [2837019] 0 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST002264 Genome-wide genotyping array 932 2012-12-05 23010768 Meier S 2012-09-25 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/23010768 Genome-wide significant association between a 'negative mood delusions' dimension in bipolar disorder and genetic variation on chromosome 3q26.1. Bipolar disorder (Negative mood delusions) 927 European ancestry cases, 2,168 European ancestry controls 1,247 European ancestry cases, 1,434 European ancestry controls Illumina [378570] 0 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST001695 Genome-wide genotyping array 3095 2012-11-30 23028347 Liu F 2012-09-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/23028347 A genome-wide association study identifies five loci influencing facial morphology in Europeans. Facial morphology 5,388 European ancestry individuals 4,071 European ancestry individuals Affymetrix, Illumina [2558979] (imputed) 0 facial morphology http://www.ebi.ac.uk/efo/EFO_0004743 GCST001678 Genome-wide genotyping array 5388 2013-04-04 23319000 Luykx JJ 2013-01-15 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/23319000 Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid. Metabolite levels (HVA/5-HIAA ratio) up to 398 European ancestry individuals NA Illumina [5767231] (imputed) 9 HVA measurement, 5-HIAA measurement http://www.ebi.ac.uk/efo/EFO_0005131, http://www.ebi.ac.uk/efo/EFO_0005132 GCST001818 Genome-wide genotyping array 398 2013-04-04 23319000 Luykx JJ 2013-01-15 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/23319000 Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid. Metabolite levels (HVA-5-HIAA Factor score) up to 398 European ancestry individuals NA Illumina [5767231] (imputed) 12 HVA measurement, 5-HIAA measurement http://www.ebi.ac.uk/efo/EFO_0005131, http://www.ebi.ac.uk/efo/EFO_0005132 GCST001817 Genome-wide genotyping array 398 2013-04-04 23319000 Luykx JJ 2013-01-15 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/23319000 Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid. Metabolite levels (HVA) up to 398 European ancestry individuals NA Illumina [5767231] (imputed) 13 HVA measurement http://www.ebi.ac.uk/efo/EFO_0005131 GCST001824 Genome-wide genotyping array 398 2013-04-04 23319000 Luykx JJ 2013-01-15 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/23319000 Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid. Metabolite levels (5-HIAA) up to 398 European ancestry individuals NA Illumina [5767231] (imputed) 13 5-HIAA measurement http://www.ebi.ac.uk/efo/EFO_0005132 GCST001820 Genome-wide genotyping array 398 2013-04-04 23319000 Luykx JJ 2013-01-15 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/23319000 Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid. Metabolite levels (MHPG) up to 398 European ancestry individuals NA Illumina [5767231] (imputed) 20 MHPG measurement http://www.ebi.ac.uk/efo/EFO_0005133 GCST001822 Genome-wide genotyping array 398 2013-04-04 23319000 Luykx JJ 2013-01-15 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/23319000 Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid. Metabolite levels (5-HIAA/ MHPG Ratio) up to 398 European ancestry individuals NA Illumina [5767231] (imputed) 11 MHPG measurement, 5-HIAA measurement http://www.ebi.ac.uk/efo/EFO_0005133, http://www.ebi.ac.uk/efo/EFO_0005132 GCST001821 Genome-wide genotyping array 398 2013-04-04 23319000 Luykx JJ 2013-01-15 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/23319000 Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid. Metabolite levels (HVA/MHPG ratio) up to 398 European ancestry individuals NA Illumina [5767231] (imputed) 25 HVA measurement, MHPG measurement http://www.ebi.ac.uk/efo/EFO_0005131, http://www.ebi.ac.uk/efo/EFO_0005133 GCST001823 Genome-wide genotyping array 398 2012-05-25 22504419 Taal HR 2012-04-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22504419 Common variants at 12q15 and 12q24 are associated with infant head circumference. Head circumference (infant) 10,768 European ancestry infants 8,321 European ancestry infants Affymetrix, Illumina [~ 2400000] (imputed) 3 infant head circumference http://www.ebi.ac.uk/efo/EFO_0004577 GCST001484 Genome-wide genotyping array 10768 2012-11-20 22959728 Ahmeti KB 2012-09-05 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/22959728 Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1. Amyotrophic lateral sclerosis (age of onset) 4,243 European ancestry cases NA Illumina [254145] 13 amyotrophic lateral sclerosis, age at onset http://www.ebi.ac.uk/efo/EFO_0000253, http://www.ebi.ac.uk/efo/EFO_0004847 GCST001663 Genome-wide genotyping array 4243 2012-11-20 22959728 Ahmeti KB 2012-09-05 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/22959728 Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1. Amyotrophic lateral sclerosis 4,243 European ancestry cases, 5,112 European ancestry controls NA Illumina [254145] 15 amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0000253 GCST001664 Genome-wide genotyping array 9355 2017-09-28 22959728 Ahmeti KB 2012-09-05 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/22959728 Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1. Amyotrophic lateral sclerosis (C9orf72 mutation interaction) 4,243 European ancestry cases NA Illumina [254145] 3 amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0000253 GCST004791 Genome-wide genotyping array 4243 2017-09-28 22959728 Ahmeti KB 2012-09-05 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/22959728 Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1. Amyotrophic lateral sclerosis in C9orf72 mutation negative individuals Up to 4,243 European ancestry cases, up to 5,112 European ancestry controls NA Illumina [254145] 4 amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0000253 GCST004793 Genome-wide genotyping array 9355 2017-09-28 22959728 Ahmeti KB 2012-09-05 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/22959728 Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1. Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals up to 4,243 European ancestry cases, up to 5,112 European ancestry controls NA Illumina [254145] 6 amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0000253 GCST004792 Genome-wide genotyping array 9355 2012-10-24 21833088 Sawcer S 2011-08-11 Nature www.ncbi.nlm.nih.gov/pubmed/21833088 Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Multiple sclerosis 9,772 European ancestry cases, 16,849 European ancestry controls 4,218 European ancestry cases, 7,296 European ancestry controls Illumina [465434] 87 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST001198 Genome-wide genotyping array 26621 2012-06-22 22558069 Osman W 2012-04-27 PLoS One www.ncbi.nlm.nih.gov/pubmed/22558069 Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese. Non-albumin protein levels Up to 9,103 Japanese ancestry individuals Up to 1,629 Japanese ancestry individuals Illumina [2178644] (imputed) 5 serum non-albumin protein measurement http://www.ebi.ac.uk/efo/EFO_0004568 GCST001496 Genome-wide genotyping array 9103 2012-09-12 22763476 Zhang D 2012-07-05 Hypertens Res www.ncbi.nlm.nih.gov/pubmed/22763476 Genome-wide linkage and association scans for pulse pressure in Chinese twins. Blood pressure 63 Chinese ancestry dizygotic twin pairs NA Affymetrix [~ 900000] 4 blood pressure http://www.ebi.ac.uk/efo/EFO_0004325 GCST001598 Genome-wide genotyping array 63 2011-10-11 21909110 Wain LV 2011-09-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21909110 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Blood pressure 74,064 European ancestry individuals 48,607 European ancestry individuals Affymetrix, Illumina, Perlegen [NR] (imputed) 27 blood pressure http://www.ebi.ac.uk/efo/EFO_0004325 GCST001236 Genome-wide genotyping array 74064 2011-10-11 21909110 Wain LV 2011-09-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21909110 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Blood pressure 74,064 European ancestry individuals 48,607 European ancestry individuals Affymetrix, Illumina, Perlegen [NR] (imputed) 14 blood pressure http://www.ebi.ac.uk/efo/EFO_0004325 GCST001235 Genome-wide genotyping array 74064 2008-06-16 17053108 Dewan A 2006-10-19 Science www.ncbi.nlm.nih.gov/pubmed/17053108 HTRA1 promoter polymorphism in wet age-related macular degeneration. Age-related macular degeneration (wet) 96 South East Asian ancestry cases, 130 South East Asian ancestry controls NA Affymetrix [97824] 1 age-related macular degeneration http://www.ebi.ac.uk/efo/EFO_0001365 GCST000006 Genome-wide genotyping array 226 2009-09-28 17848626 Florez JC 2007-09-10 Diabetes www.ncbi.nlm.nih.gov/pubmed/17848626 A 100K genome-wide association scan for diabetes and related traits in the Framingham Heart Study: replication and integration with other genome-wide datasets. Type 2 diabetes and 6 quantitative traits 1,087 European ancestry individuals from 307 families 1,465 European ancestry individuals, 1,464 European ancestry cases, 1,467 European ancestry controls, 300 Pima Indian ancestry cases, 334 Pima Indian ancestry controls, 287 Mexican American cases, 316 Mexican American controls, 124 Old Order Amish cases, 295 Old Order Amish controls Affymetrix [66543] 0 insulin measurement, glucose measurement, type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0004467, http://www.ebi.ac.uk/efo/EFO_0004468, http://www.ebi.ac.uk/efo/EFO_0001360 GCST000073 Genome-wide genotyping array 1394 2011-04-06 21355061 Boger CA 2011-02-25 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/21355061 CUBN is a gene locus for albuminuria. Urinary albumin excretion 31,580 European ancestry individuals 31,277 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 1 albuminuria http://www.ebi.ac.uk/efo/EFO_0004285 GCST000988 Genome-wide genotyping array 31580 2013-04-27 23358156 Benyamin B 2013-01-29 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/23358156 Childhood intelligence is heritable, highly polygenic and associated with FNBP1L. Intelligence (childhood) 12,441 European ancestry children 5,548 European ancestry children Affymetrix, Illumina [138093] (imputed) 6 intelligence http://www.ebi.ac.uk/efo/EFO_0004337 GCST001837 Genome-wide genotyping array 12441 2014-01-07 21041247 Perlis RH 2010-11-01 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/21041247 Genome-wide association study of suicide attempts in mood disorder patients. Suicide risk 3,117 European ancestry Bipolar disorder cases, 1,273 European ancestry Major depressive disorder cases 2,698 European ancestry Bipolar disorder cases, 1,649 Major depressive disorder cases Affymetrix [1922309] (imputed) 4 mental or behavioural disorder, attempted suicide http://www.ebi.ac.uk/efo/EFO_0000677, http://www.ebi.ac.uk/efo/EFO_0004321 GCST000854 Genome-wide genotyping array 4390 2010-10-17 20864672 Waterworth DM 2010-09-23 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/20864672 Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Triglycerides up to 17,723 European ancestry individuals up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals Affymetrix, Illumina, Perlegen [2155369] (imputed) 11 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST000809 Genome-wide genotyping array 17723 2010-10-17 20864672 Waterworth DM 2010-09-23 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/20864672 Genetic variants influencing circulating lipid levels and risk of coronary artery disease. LDL cholesterol up to 17,723 European ancestry individuals up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals Affymetrix, Illumina, Perlegen [2155369] (imputed) 11 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST000807 Genome-wide genotyping array 17723 2010-10-17 20864672 Waterworth DM 2010-09-23 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/20864672 Genetic variants influencing circulating lipid levels and risk of coronary artery disease. HDL cholesterol up to 17,723 European ancestry individuals up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals Affymetrix, Illumina, Perlegen [2155369] (imputed) 12 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST000805 Genome-wide genotyping array 17723 2012-01-14 20600896 Engelman CD 2010-06-26 J Steroid Biochem Mol Biol www.ncbi.nlm.nih.gov/pubmed/20600896 Genome-wide association study of vitamin D concentrations in Hispanic Americans: the IRAS family study. Vitamin D levels 229 Hispanic individuals from 34 families 961 Hispanic individuals Illumina [309200] 0 vitamin D measurement http://www.ebi.ac.uk/efo/EFO_0004631 GCST000711 Genome-wide genotyping array 263 2011-04-07 21408207 Chung SA 2011-03-03 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21408207 Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. Systemic lupus erythematosus 811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls NA Illumina [421318] (imputed) 24 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST000996 Genome-wide genotyping array 6530 2008-06-16 17486107 Baum AE 2007-05-08 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/17486107 A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder. Bipolar disorder 461 European ancestry cases, 563 European ancestry controls 772 European ancestry cases, 876 European ancestry controls Illumina [555235] 1 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST000033 Genome-wide genotyping array 1024 2011-04-06 21390209 Hu X 2011-02-24 PLoS One www.ncbi.nlm.nih.gov/pubmed/21390209 Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease. Alzheimer's disease (late onset) 1,831 European ancestry cases, 1,764 European ancestry controls 751 cases, 751 controls Affymetrix, Illumina [NR] (imputed) 2 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST000986 Genome-wide genotyping array 3595 2008-09-12 18245381 Uda M 2008-02-05 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/18245381 Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia. Fetal hemoglobin levels 4,305 European ancestry individuals 521 European ancestry individuals Affymetrix [362129] 2 fetal hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004576 GCST000150 Genome-wide genotyping array 4305 2008-09-15 18262040 Sandhu MS 2008-02-09 Lancet www.ncbi.nlm.nih.gov/pubmed/18262040 LDL-cholesterol concentrations: a genome-wide association study. LDL cholesterol 11,685 European ancestry individuals Up to 4,979 European ancestry individuals Affymetrix, Illumina [up to 461986] 3 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST000151 Genome-wide genotyping array 11685 2015-05-23 21307088 Khor CC 2011-02-09 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21307088 Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area. Optic disc area 2,132 Indian ancestry individuals, 2,313 Malay ancestry individuals 9,326 European ancestry individuals Illumina [551808] 4 optic disc size measurement http://www.ebi.ac.uk/efo/EFO_0004832 GCST000970 Genome-wide genotyping array 4445 2013-11-29 23732972 Hashimoto R 2013-06-01 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/23732972 Genome-wide association study of cognitive decline in schizophrenia. Cognitive decline 166 Japanese ancestry schizophrenia cases, 323 Japanese ancestry controls 339 schizophrenia cases Affymetrix [541657] 0 Mental deterioration http://purl.obolibrary.org/obo/HP_0001268 GCST002055 Genome-wide genotyping array 489 2008-07-11 18587394 Barrett JC 2008-06-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18587394 Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Crohn's disease 3,230 European ancestry cases, 4,829 European ancestry controls 1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls Affymetrix, Illumina [635547] (imputed) 30 Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000384 GCST000207 Genome-wide genotyping array 8059 2008-07-11 18594024 Sarasquete ME 2008-07-01 Blood www.ncbi.nlm.nih.gov/pubmed/18594024 Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: a genome-wide single nucleotide polymorphism analysis. Osteonecrosis of the jaw 22 European ancestry cases, 65 European ancestry controls NA Affymetrix [339972] 1 osteonecrosis http://www.ebi.ac.uk/efo/EFO_0004259 GCST000209 Genome-wide genotyping array 87 2009-09-28 17997608 Li S 2007-11-09 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/17997608 The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts. Urate levels 4,305 Sardinian individuals 1,301 European ancestry individuals Affymetrix [362129] 1 urate measurement http://www.ebi.ac.uk/efo/EFO_0004531 GCST000123 Genome-wide genotyping array 4305 2010-07-12 20543847 Turnbull C 2010-06-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20543847 Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer. Testicular germ cell cancer 979 European ancestry cases, 4,947 European ancestry controls 664 European ancestry cases, 3,456 European ancestry controls Illumina [298782] 6 testicular carcinoma http://www.ebi.ac.uk/efo/EFO_0005088 GCST000701 Genome-wide genotyping array 5926 2009-06-19 19508998 Knauff EA 2009-06-09 Hum Reprod www.ncbi.nlm.nih.gov/pubmed/19508998 Genome-wide association study in premature ovarian failure patients suggests ADAMTS19 as a possible candidate gene. Premature ovarian failure 99 European ancestry cases, 235 European ancestry controls 60 European ancestry cases, 90 European ancestry controls Illumina [309158] 0 primary ovarian insufficiency http://www.ebi.ac.uk/efo/EFO_0004266 GCST000422 Genome-wide genotyping array 334 2010-06-14 20463881 Liu F 2010-05-16 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/20463881 Digital quantification of human eye color highlights genetic association of three new loci. Eye color traits 5,951 European ancestry individuals 3,543 European ancestry individuals Illumina [2543887] (imputed) 3 eye color http://www.ebi.ac.uk/efo/EFO_0003949 GCST000685 Genome-wide genotyping array 5951 2008-06-16 17554300 Wellcome Trust Case Control Consortium 2007-06-07 Nature www.ncbi.nlm.nih.gov/pubmed/17554300 Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Crohn's disease 1,748 European ancestry cases, 2,938 European ancestry controls (see Parkes 2007) Affymetrix [469557] 13 Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000384 GCST000042 Genome-wide genotyping array 4686 2008-06-16 17554300 Wellcome Trust Case Control Consortium 2007-06-07 Nature www.ncbi.nlm.nih.gov/pubmed/17554300 Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Hypertension 1,952 European ancestry cases, 2,938 European ancestry controls NA Affymetrix [469557] 2 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST000041 Genome-wide genotyping array 4890 2008-06-16 17554300 Wellcome Trust Case Control Consortium 2007-06-07 Nature www.ncbi.nlm.nih.gov/pubmed/17554300 Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Type 2 diabetes 1,924 European ancestry cases, 2,938 European ancestry controls (see Zeggini 2007) Affymetrix [469557] 7 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST000047 Genome-wide genotyping array 4862 2008-06-16 17554300 Wellcome Trust Case Control Consortium 2007-06-07 Nature www.ncbi.nlm.nih.gov/pubmed/17554300 Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Rheumatoid arthritis 1,860 European ancestry cases, 2,938 European ancestry controls NA Affymetrix [469557] 7 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST000040 Genome-wide genotyping array 4798 2008-06-16 17554300 Wellcome Trust Case Control Consortium 2007-06-07 Nature www.ncbi.nlm.nih.gov/pubmed/17554300 Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Coronary heart disease 1,926 European ancestry cases, 2,938 European ancestry controls (see Samani 2007) Affymetrix [469557] 4 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST000045 Genome-wide genotyping array 4864 2008-06-16 17554300 Wellcome Trust Case Control Consortium 2007-06-07 Nature www.ncbi.nlm.nih.gov/pubmed/17554300 Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Bipolar disorder 1,868 European ancestry cases, 2,938 European ancestry controls NA Affymetrix [469557] 7 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST000044 Genome-wide genotyping array 4806 2008-06-16 17554300 Wellcome Trust Case Control Consortium 2007-06-07 Nature www.ncbi.nlm.nih.gov/pubmed/17554300 Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Type 1 diabetes 1,963 European ancestry cases, 2,938 European ancestry controls (see Todd 2007) Affymetrix [469557] 10 type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001359 GCST000043 Genome-wide genotyping array 4901 2013-03-28 23291589 Lu Y 2013-01-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23291589 Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus. Corneal structure 13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals NA Affymetrix, Illumina [~ 1000000] (imputed) 26 corneal topography http://www.ebi.ac.uk/efo/EFO_0004345 GCST001806 Genome-wide genotyping array 20020 2010-01-13 20037589 Illig T 2009-12-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20037589 A genome-wide perspective of genetic variation in human metabolism. Metabolite levels 1,029 European ancestry individuals 1,202 European ancestry individuals Affymetrix [517480] 5 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST000550 Genome-wide genotyping array 1029 2015-05-15 21353194 Cichon S 2011-02-23 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/21353194 Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. Bipolar disorder 682 European ancestry cases, 1,300 European ancestry controls 7,759 European ancestry cases, 34,062 European ancestry controls Illumina [511978] 1 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST000985 Genome-wide genotyping array 1982 2009-12-29 19767753 Eeles RA 2009-09-20 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19767753 Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. Prostate cancer 1,854 European ancestry cases, 1,894 European ancestry controls 19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry Illumina [541129] 19 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST000488 Genome-wide genotyping array 3748 2009-09-29 19734901 van Es MA 2009-09-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19734901 Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis 2,323 European ancestry cases, 9,013 European ancestry controls 2,532 European ancestry cases, 5,940 European ancestry controls Illumina [292768] 8 amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0000253 GCST000481 Genome-wide genotyping array 11336 2009-09-28 17767157 Weedon MN 2007-09-02 Nat Genet www.ncbi.nlm.nih.gov/pubmed/17767157 A common variant of HMGA2 is associated with adult and childhood height in the general population. Height 4,921 European ancestry individuals 19,064 European ancestry adult individuals, 6,827 European ancestry children Affymetrix [364301] 1 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST000068 Genome-wide genotyping array 4921 2010-01-19 20038948 Papassotiropoulos A 2009-12-29 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/20038948 A genome-wide survey of human short-term memory. Memory (short-term) 333 European ancestry individuals 777 European ancestry young individuals, 922 European ancestry elderly individuals Affymetrix [841663] 0 short-term memory http://www.ebi.ac.uk/efo/EFO_0004335 GCST000552 Genome-wide genotyping array 333 2013-09-27 20197096 Stein JL 2010-03-01 Neuroimage www.ncbi.nlm.nih.gov/pubmed/20197096 Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease. Brain structure (hippocampal volume) 162 European ancestry Alzheimer's disease cases, 343 European ancestry amnestic mild cognitive impairment cases, 193 European ancestry healthy elderly controls NA Illumina [546314] 4 brain measurement, hippocampal volume http://www.ebi.ac.uk/efo/EFO_0004464, http://www.ebi.ac.uk/efo/EFO_0005035 GCST000615 Genome-wide genotyping array 698 2013-09-27 20197096 Stein JL 2010-03-01 Neuroimage www.ncbi.nlm.nih.gov/pubmed/20197096 Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease. Brain structure (temporal lobe volume) 173 European ancestry Alzheimer's disease cases, 361 European ancestry Mild Cognitive Impairment cases, 208 European ancestry controls NA Illumina [546314] 5 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST000614 Genome-wide genotyping array 742 2010-01-07 20039944 Docherty SJ 2009-11-10 Genes Brain Behav www.ncbi.nlm.nih.gov/pubmed/20039944 A genome-wide association study identifies multiple loci associated with mathematics ability and disability. Mathematical ability 600 European ancestry high-performing children, 600 European ancestry low-performing children 1,954 European ancestry children Affymetrix [358948] 0 mathematical ability http://www.ebi.ac.uk/efo/EFO_0004875 GCST000524 Genome-wide genotyping array 1200 2010-02-02 20062062 Reveille JD 2010-01-10 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20062062 Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. Ankylosing spondylitis 2,053 European ancestry cases, 5,140 European ancestry controls 898 European ancestry cases, 1,518 European ancestry controls Illumina [288662] 9 ankylosing spondylitis http://www.ebi.ac.uk/efo/EFO_0003898 GCST000563 Genome-wide genotyping array 7193 2008-06-16 17618284 Tomlinson I 2007-07-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/17618284 A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. Colorectal cancer 930 European ancestry cases, 960 European ancestry controls 7,334 European ancestry cases, 5,246 European ancestry controls Illumina [547647] 1 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST000053 Genome-wide genotyping array 1890 2012-02-21 22291604 Okada Y 2012-01-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22291604 A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese. Systemic lupus erythematosus 891 Japanese ancestry cases, 3,384 Japanese ancestry controls 1,387 Japanese ancestry cases, 28,564 Japanese ancestry controls Illumina [430797] 2 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST001384 Genome-wide genotyping array 4275 2012-02-02 22233651 Kwak SH 2012-01-10 Diabetes www.ncbi.nlm.nih.gov/pubmed/22233651 A genome-wide association study of gestational diabetes mellitus in Korean women. Diabetes (gestational) 468 Korean ancestry cases, 1,242 Korean ancestry controls 931 Korean ancestry cases, 783 Korean ancestry controls Affymetrix [2188613] (imputed) 3 gestational diabetes http://www.ebi.ac.uk/efo/EFO_0004593 GCST001375 Genome-wide genotyping array 1710 2011-03-02 21244703 Wang JH 2011-01-18 Genome Med www.ncbi.nlm.nih.gov/pubmed/21244703 Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data. Multiple sclerosis 2,124 cases, 6,720 controls 1,618 cases, 1,988 controls Affymetrix, Illumina [~ 2560000] (imputed) 3 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST000949 Genome-wide genotyping array 8844 2010-10-12 20862305 Shu XO 2010-09-16 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/20862305 Identification of new genetic risk variants for type 2 diabetes. Type 2 diabetes 1,019 Chinese ancestry cases, 1,710 Chinese ancestry controls 2,591 European ancestry cases, 3,052 European ancestry controls, 6,184 East Asian cases, 9,853 East Asian controls Affymetrix [590887] 4 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST000796 Genome-wide genotyping array 2729 2011-04-29 21452313 Freudenberg J 2011-04-01 Arthritis Rheum www.ncbi.nlm.nih.gov/pubmed/21452313 Genome-wide association study of rheumatoid arthritis in Koreans: population-specific loci as well as overlap with European susceptibility loci. Rheumatoid arthritis 801 Korean ancestry cases, 757 Korean ancestry controls 718 Korean ancestry cases, 719 Korean ancestry controls Illumina [441398] 5 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST001022 Genome-wide genotyping array 1558 2011-04-11 21386085 Kraja AT 2011-03-08 Diabetes www.ncbi.nlm.nih.gov/pubmed/21386085 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. Metabolic syndrome (bivariate traits) 22,161 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 16 metabolic syndrome http://www.ebi.ac.uk/efo/EFO_0000195 GCST001007 Genome-wide genotyping array 22161 2011-04-11 21386085 Kraja AT 2011-03-08 Diabetes www.ncbi.nlm.nih.gov/pubmed/21386085 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. Metabolic syndrome 22,161 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 5 metabolic syndrome http://www.ebi.ac.uk/efo/EFO_0000195 GCST001003 Genome-wide genotyping array 22161 2011-04-11 21386085 Kraja AT 2011-03-08 Diabetes www.ncbi.nlm.nih.gov/pubmed/21386085 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. Waist Circumference - Triglycerides (WC-TG) 22,161 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 7 triglyceride measurement, metabolic syndrome http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0000195 GCST001006 Genome-wide genotyping array 22161 2011-04-11 21386085 Kraja AT 2011-03-08 Diabetes www.ncbi.nlm.nih.gov/pubmed/21386085 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. HDL Cholesterol - Triglycerides (HDLC-TG) 22,161 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 8 triglyceride measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0004612 GCST001005 Genome-wide genotyping array 22161 2011-04-11 21386085 Kraja AT 2011-03-08 Diabetes www.ncbi.nlm.nih.gov/pubmed/21386085 A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. Triglycerides-Blood Pressure (TG-BP) 22,161 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 6 triglyceride measurement, blood pressure http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0004325 GCST001004 Genome-wide genotyping array 22161 2009-10-05 19767754 Gudmundsson J 2009-09-20 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19767754 Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility. Prostate cancer Up to 1,968 European ancestry cases, 35,382 European ancestry controls Up to 11,806 European ancestry cases, 12,387 European ancestry controls Illumina [310520] 8 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST000489 Genome-wide genotyping array 37350 2013-06-14 23382691 Lauc G 2013-01-31 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/23382691 Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. IgG glycosylation 2,247 European ancestry individuals NA Illumina [~ 2500000] (imputed) 693 serum IgG glycosylation measurement http://www.ebi.ac.uk/efo/EFO_0005193 GCST001848 Genome-wide genotyping array 2247 2013-06-14 23382691 Lauc G 2013-01-31 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/23382691 Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. IgG glycosylation 1,848 European ancestry individuals NA Illumina [~ 2500000] (imputed) 6 serum IgG glycosylation measurement http://www.ebi.ac.uk/efo/EFO_0005193 GCST001849 Genome-wide genotyping array 1848 2009-03-30 19260139 Polasek O 2009-02-01 Croat Med J www.ncbi.nlm.nih.gov/pubmed/19260139 Genome-wide association study of anthropometric traits in Korcula Island, Croatia. Anthropometric traits 898 Korculan (founder/genetic isolate) individuals NA Illumina [316730] 13 anthropometric measurement http://www.ebi.ac.uk/efo/EFO_0004302 GCST000327 Genome-wide genotyping array 898 2012-03-31 22219177 Tao S 2012-01-04 Carcinogenesis www.ncbi.nlm.nih.gov/pubmed/22219177 A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants. Prostate cancer (SNP x SNP interaction) 4,723 European ancestry cases, 4,792 European ancestry controls NA Affymetrix, Illumina [1117531] (imputed) 51 genetic variation, prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0004828, http://www.ebi.ac.uk/efo/EFO_0001663 GCST001370 Genome-wide genotyping array 9515 2008-06-16 18193046 Kooner JS 2008-01-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18193046 Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides. Triglycerides 1,005 European ancestry male individuals, 1,006 Indian Asian ancestry male individuals 6,827 European ancestry individuals, 2,528 Mexican ancestry individuals, 1,181 Indian Asian ancestry female individuals Perlegen [up to 216774] 4 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST000137 Genome-wide genotyping array 2011 2013-04-19 23326517 Holliday EG 2013-01-11 PLoS One www.ncbi.nlm.nih.gov/pubmed/23326517 Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. Age-related macular degeneration 3,772 European ancestry cases, 16,033 European ancestry controls 264 Asian ancestry cases, 3,926 Asian ancestry controls Affymetrix, Illumina [~ 2500000] (imputed) 31 age-related macular degeneration http://www.ebi.ac.uk/efo/EFO_0001365 GCST001814 Genome-wide genotyping array 19805 2009-11-09 19838193 Han JW 2009-10-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19838193 Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Systemic lupus erythematosus 1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls 3,152 Han Chinese ancestry cases, 7,050 Han Chinese ancestry controls Illumina [493955] 18 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST000507 Genome-wide genotyping array 2252 2009-09-28 18193045 Sanna S 2008-01-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18193045 Common variants in the GDF5-UQCC region are associated with variation in human height. Height 1,084 European ancestry cases, 1,287 European ancestry controls, 4,298 European individuals 23,684 European ancestry individuals, 3,860 African American individuals Affymetrix, Illumina [~ 2261000] (imputed) 5 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST000136 Genome-wide genotyping array 6669 2008-12-11 19043545 Gieger C 2008-11-28 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/19043545 Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. Metabolite levels 284 European ancestry male individuals NA Affymetrix [187454] 16 phenylalanine measurement, acylcarnitine measurement, carbohydrate measurement, tyrosine measurement, sphingolipid measurement, lysine measurement, lipid measurement, phospholipid measurement, serotonin measurement http://www.ebi.ac.uk/efo/EFO_0005001, http://www.ebi.ac.uk/efo/EFO_0005059, http://www.ebi.ac.uk/efo/EFO_0004998, http://www.ebi.ac.uk/efo/EFO_0005058, http://www.ebi.ac.uk/efo/EFO_0004622, http://www.ebi.ac.uk/efo/EFO_0005002, http://www.ebi.ac.uk/efo/EFO_0004529, http://www.ebi.ac.uk/efo/EFO_0004639, http://www.ebi.ac.uk/efo/EFO_0004846 GCST000274 Genome-wide genotyping array 284 2011-01-09 21182207 Salyakina D 2010-12-01 Autism Res www.ncbi.nlm.nih.gov/pubmed/21182207 Variants in several genomic regions associated with asperger disorder. Asperger disorder 848 individuals from 232 families NA Illumina [439282] (imputed) 5 Asperger syndrome http://www.ebi.ac.uk/efo/EFO_0003757 GCST000904 Genome-wide genotyping array 1080 2008-09-12 17903300 Fox CS 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903300 Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. Waist circumference 1,079 European ancestry individuals from 310 families NA Affymetrix [70897] 2 waist circumference http://www.ebi.ac.uk/efo/EFO_0004342 GCST000084 Genome-wide genotyping array 1389 2008-09-17 17903300 Fox CS 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903300 Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. Body mass index 1,341 European ancestry individuals from 310 families NA Affymetrix [70897] 3 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST000090 Genome-wide genotyping array 1651 2008-09-16 18193043 Willer CJ 2008-01-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18193043 Newly identified loci that influence lipid concentrations and risk of coronary artery disease. HDL cholesterol 8,656 European ancestry individuals 11,437 European ancestry individuals Affymetrix, Illumina [~ 2261000] (imputed) 10 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST000135 Genome-wide genotyping array 8656 2008-09-16 18193043 Willer CJ 2008-01-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18193043 Newly identified loci that influence lipid concentrations and risk of coronary artery disease. LDL cholesterol 8,589 European ancestry individuals 12,981 European ancestry individuals Affymetrix, Illumina [~ 2261000] (imputed) 7 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST000132 Genome-wide genotyping array 8589 2008-09-16 18193043 Willer CJ 2008-01-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18193043 Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Triglycerides 8,684 European ancestry individuals 9,741 European ancestry individuals Affymetrix, Illumina [~ 2261000] (imputed) 9 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST000139 Genome-wide genotyping array 8684 2008-09-10 17903298 Meigs JB 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903298 Genome-wide association with diabetes-related traits in the Framingham Heart Study. Fasting plasma glucose 1,027 individuals NA Affymetrix [70897] 6 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST000085 Genome-wide genotyping array 1027 2009-09-15 17903298 Meigs JB 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903298 Genome-wide association with diabetes-related traits in the Framingham Heart Study. Diabetes (incident) 91 cases, 1,083 controls NA Affymetrix [70897] 1 diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0000400 GCST000108 Genome-wide genotyping array 1174 2008-09-10 17903298 Meigs JB 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903298 Genome-wide association with diabetes-related traits in the Framingham Heart Study. Diabetes related insulin traits Up to 982 individuals NA Affymetrix [70897] 4 insulin sensitivity measurement, HbA1c measurement, insulin resistance, fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004471, http://www.ebi.ac.uk/efo/EFO_0004541, http://www.ebi.ac.uk/efo/EFO_0002614, http://www.ebi.ac.uk/efo/EFO_0004466 GCST000077 Genome-wide genotyping array 982 2008-06-16 17827064 van Es MA 2007-09-07 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/17827064 ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study. Amyotrophic lateral sclerosis 461 European ancestry cases, 450 European ancestry controls 876 European ancestry cases, 906 European ancestry controls Illumina [311946] 1 amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0000253 GCST000072 Genome-wide genotyping array 911 2009-09-28 17671248 Dunckley T 2007-08-01 N Engl J Med www.ncbi.nlm.nih.gov/pubmed/17671248 Whole-genome analysis of sporadic amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis 386 European ancestry cases, 542 European ancestry controls 901 cases and 1,025 controls of European, Hispanic, Asian, American Indian, Pacific Islander, and other ancestries Affymetrix, Illumina [776955] 0 amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0000253 GCST000065 Genome-wide genotyping array 928 2008-06-16 17690259 Thorleifsson G 2007-08-09 Science www.ncbi.nlm.nih.gov/pubmed/17690259 Common sequence variants in the LOXL1 gene confer susceptibility to exfoliation glaucoma. Glaucoma (exfoliation) 75 European ancestry cases, 14,474 European ancestry controls 199 European ancestry cases, 198 European ancestry controls Illumina [304250] 1 exfoliation syndrome http://www.ebi.ac.uk/efo/EFO_0004235 GCST000067 Genome-wide genotyping array 14549 2008-06-16 17068223 Duerr RH 2006-10-26 Science www.ncbi.nlm.nih.gov/pubmed/17068223 A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Inflammatory bowel disease 547 European ancestry cases, 548 European ancestry controls 1,151 cases from 595 families, 433 controls Illumina [308332] 1 inflammatory bowel disease http://www.ebi.ac.uk/efo/EFO_0003767 GCST000008 Genome-wide genotyping array 1095 2009-09-28 17053149 Papassotiropoulos A 2006-10-20 Science www.ncbi.nlm.nih.gov/pubmed/17053149 Common Kibra alleles are associated with human memory performance. Memory performance 341 European ancestry individuals 662 European ancestry individuals, 18 Hispanic, African American, Native American, and Asian ancestry individuals Affymetrix [178390] 0 memory performance http://www.ebi.ac.uk/efo/EFO_0004874 GCST000007 Genome-wide genotyping array 341 2012-01-28 22197932 Paternoster L 2011-12-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22197932 Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis. Atopic dermatitis 5,606 European ancestry cases, 20,565 European ancestry controls 5,419 European ancestry cases, 19,833 European ancestry controls Affymetrix, Illumina [~ 2500000] (imputed) 6 atopic eczema http://www.ebi.ac.uk/efo/EFO_0000274 GCST001363 Genome-wide genotyping array 26171 2008-11-26 18978792 Cooper JD 2008-11-02 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18978792 Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci. Type 1 diabetes 3,561 European ancestry cases, 4,646 European ancestry controls 6,225 European ancestry cases, 6,946 European ancestry controls, 3,064 European ancestry trios from 2,828 families Affymetrix [up to 335565] 14 type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001359 GCST000258 Genome-wide genotyping array 8207 2010-05-11 20397748 Liu JZ 2010-04-01 Twin Res Hum Genet www.ncbi.nlm.nih.gov/pubmed/20397748 Genome-wide association study of height and body mass index in Australian twin families. Body mass index 11,536 European ancestry individuals NA Illumina [559712] (imputed) 2 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST000642 Genome-wide genotyping array 11536 2010-05-11 20397748 Liu JZ 2010-04-01 Twin Res Hum Genet www.ncbi.nlm.nih.gov/pubmed/20397748 Genome-wide association study of height and body mass index in Australian twin families. Height 11,536 European ancestry individuals NA Illumina [559712] (imputed) 8 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST000644 Genome-wide genotyping array 11536 2008-09-15 18159244 Hinney A 2007-12-26 PLoS One www.ncbi.nlm.nih.gov/pubmed/18159244 Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants. Obesity (early onset extreme) 487 European ancestry cases, 442 European ancestry controls 2,269 European ancestry individuals from 644 families Affymetrix [440794] 1 obesity http://www.ebi.ac.uk/efo/EFO_0001073 GCST000129 Genome-wide genotyping array 929 2012-09-20 22807686 Li S 2012-07-12 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22807686 GWAS identifies novel susceptibility loci on 6p21.32 and 21q21.3 for hepatocellular carcinoma in chronic hepatitis B virus carriers. Hepatocellular carcinoma 1,538 Han Chinese ancestry HBV-positive HCC cases, 1,465 Han Chinese ancestry chronic HBV carriers 4,431 Han Chinese ancestry HBV-positive HCC cases, 4,725 Han Chinese ancestry chronic HBV carriers NR [523663] 3 hepatocellular carcinoma http://www.ebi.ac.uk/efo/EFO_0000182 GCST001603 Genome-wide genotyping array 3003 2010-04-12 20303064 Houlihan LM 2010-03-18 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/20303064 Common variants of large effect in F12, KNG1, and HRG are associated with activated partial thromboplastin time. Activated partial thromboplastin time 1,431 European ancestry individuals NA Illumina [542050] 3 partial thromboplastin time http://www.ebi.ac.uk/efo/EFO_0004310 GCST000631 Genome-wide genotyping array 1431 2009-12-01 19880490 Tanaka T 2009-10-30 Blood www.ncbi.nlm.nih.gov/pubmed/19880490 A genome-wide association analysis of serum iron concentrations. Iron levels 1,919 European ancestry individuals 569 female indiviuals Illumina [475322] 1 iron biomarker measurement http://www.ebi.ac.uk/efo/EFO_0004461 GCST000517 Genome-wide genotyping array 1919 2009-03-28 19259986 Hattori E 2009-03-02 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/19259986 Preliminary genome-wide association study of bipolar disorder in the Japanese population. Bipolar disorder 107 Japanese ancestry cases, 107 Japanese ancestry controls 395 Japanese ancestry cases, 409 Japanese ancestry controls Affymetrix [88671] 0 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST000350 Genome-wide genotyping array 214 2009-12-29 20031603 Marroni F 2009-08-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/20031603 A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project. QT interval 2,325 European ancestry individuals NA Illumina [~ 318327] 14 QT interval http://www.ebi.ac.uk/efo/EFO_0004682 GCST000452 Genome-wide genotyping array 2325 2009-12-29 20031603 Marroni F 2009-08-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/20031603 A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project. RR interval (heart rate) 2,325 European ancestry individuals NA Illumina [~ 318327] 20 RR interval http://www.ebi.ac.uk/efo/EFO_0004831 GCST000451 Genome-wide genotyping array 2325 2013-08-13 23585552 Kirin M 2013-04-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23585552 Genome-wide association study identifies genetic risk underlying primary rhegmatogenous retinal detachment. Rhegmatogenous retinal detachment 867 European ancestry cases, 1,953 European ancestry controls 1,966 European ancestry cases, 5,918 European ancestry controls Illumina [299737] 4 rhegmatogenous retinal detachment http://www.ebi.ac.uk/efo/EFO_0005240 GCST001966 Genome-wide genotyping array 2820 2010-10-06 20844546 Adachi S 2010-09-16 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/20844546 Meta-analysis of genome-wide association scans for genetic susceptibility to endometriosis in Japanese population. Endometriosis 696 Japanese ancestry cases, 825 Japanese ancestry controls NA Affymetrix [282838] 2 endometriosis http://www.ebi.ac.uk/efo/EFO_0001065 GCST000797 Genome-wide genotyping array 1521 2009-12-04 19893584 Kim JJ 2009-11-06 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/19893584 Identification of 15 loci influencing height in a Korean population. Height 8,842 Korean ancestry individuals NA Affymetrix [334546] 15 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST000522 Genome-wide genotyping array 8842 2011-06-01 21507922 Ramsuran V 2011-05-01 Clin Infect Dis www.ncbi.nlm.nih.gov/pubmed/21507922 Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women. Platelet count 115 African ancestry HIV-negative individuals NA Illumina [874956] 10 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST001061 Genome-wide genotyping array 115 2011-06-01 21507922 Ramsuran V 2011-05-01 Clin Infect Dis www.ncbi.nlm.nih.gov/pubmed/21507922 Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women. Neutrophil count 115 African ancestry HIV-negative individuals NA Illumina [874956] 20 neutrophil count http://www.ebi.ac.uk/efo/EFO_0004833 GCST001059 Genome-wide genotyping array 115 2010-10-05 20825314 Baratz KH 2010-09-09 N Engl J Med www.ncbi.nlm.nih.gov/pubmed/20825314 E2-2 protein and Fuchs's corneal dystrophy. Fuchs's corneal dystrophy 130 European ancestry cases, 260 European ancestry controls 150 cases, 150 controls Illumina [~ 370000] 2 Fuchs endothelial corneal dystrophy http://www.orpha.net/ORDO/Orphanet_98974 GCST000790 Genome-wide genotyping array 390 2009-12-10 19915575 Simon-Sanchez J 2009-11-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19915575 Genome-wide association study reveals genetic risk underlying Parkinson's disease. Parkinson's disease 1,713 European ancestry cases, 3,978 European ancestry controls 3,361 European ancestry cases, 4,573 European ancestry controls Illumina [463185] 10 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST000528 Genome-wide genotyping array 5691 2013-09-27 23562540 Cruchaga C 2013-04-04 Neuron www.ncbi.nlm.nih.gov/pubmed/23562540 GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease. Alzheimer's disease biomarkers 591 European ancestry cases, 687 European ancestry controls NA Illumina [5815690] (imputed) 6 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST001951 Genome-wide genotyping array 1278 2010-07-01 20541252 Wang TJ 2010-06-09 Lancet www.ncbi.nlm.nih.gov/pubmed/20541252 Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Vitamin D insufficiency 16,125 European ancestry individuals 17,871 European ancestry individuals Affymetrix, Illumina [up to 2548976] (imputed) 3 vitamin D deficiency http://www.ebi.ac.uk/efo/EFO_0003762 GCST000697 Genome-wide genotyping array 16125 2009-05-05 19396169 Cho YS 2009-04-26 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19396169 A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits. Height 8,842 Korean ancestry individuals 7,861 Korean ancestry individuals Affymetrix [2156535] (imputed) 5 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST000380 Genome-wide genotyping array 8842 2009-05-05 19396169 Cho YS 2009-04-26 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19396169 A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits. Biomedical quantitative traits 8,842 Korean ancestry individuals 7,861 Korean ancestry individuals Affymetrix [2156535] (imputed) 8 diastolic blood pressure, systolic blood pressure, bone density, heart rate, waist-hip ratio, body mass index http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0003923, http://www.ebi.ac.uk/efo/EFO_0004326, http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340 GCST000381 Genome-wide genotyping array 8842 2011-04-04 21326311 Bhatnagar P 2011-02-17 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/21326311 Genome-wide association study identifies genetic variants influencing F-cell levels in sickle-cell patients. F-cell distribution in sickle cell anaemia 440 African American individuals NA Illumina [660740] 11 fetal hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004576 GCST000982 Genome-wide genotyping array 440 2009-03-29 19282985 Liu YZ 2009-03-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/19282985 Genome-wide association analyses identify SPOCK as a key novel gene underlying age at menarche. Menarche (age at onset) 477 European ancestry females 854 European ancestry siblings, 762 European ancestry female individuals, 1,387 Chinese ancestry female individuals Affymetrix [379319] 0 age at menarche http://www.ebi.ac.uk/efo/EFO_0004703 GCST000355 Genome-wide genotyping array 477 2009-01-06 19023125 Potkin SG 2008-11-20 Schizophr Bull www.ncbi.nlm.nih.gov/pubmed/19023125 A genome-wide association study of schizophrenia using brain activation as a quantitative phenotype. Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) 46 European ancestry cases, 60 European ancestry controls, 18 cases, 14 controls NA Illumina [302783] 6 schizophrenia, dorsolateral prefrontal cortex functional measurement http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0008358 GCST000271 Genome-wide genotyping array 138 2009-03-03 19151714 Meyre D 2009-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19151714 Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. Obesity 695 European ancestry adult cases, 731 European ancestry adult controls, 685 European ancestry child cases, 685 European ancestry child controls 1,171 European ancestry adult cases, 1,114 European ancestry adult controls, 4,417 European ancestry adults, 896 European ancestry child cases, 1,297 European ancestry child and young adult controls, 5,291 European ancestry children Illumina [308846] 13 obesity http://www.ebi.ac.uk/efo/EFO_0001073 GCST000317 Genome-wide genotyping array 2796 2015-05-12 22013104 Melka MG 2011-10-19 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/22013104 Genome-wide scan for loci of adolescent obesity and their relationship with blood pressure. Obesity-related traits 598 French Canadian founder adolescent individuals NA Illumina [530011] 5 fat body mass, body mass index, obesity http://www.ebi.ac.uk/efo/EFO_0005409, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0001073 GCST001288 Genome-wide genotyping array 598 2009-02-06 19169254 Nair RP 2009-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19169254 Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. Psoriasis 1,359 European ancestry cases, 1,400 European ancestry controls 5,048 European ancestry cases, 5,041 European ancestry controls Perlegen [~ 2500000] (imputed) 8 psoriasis http://www.ebi.ac.uk/efo/EFO_0000676 GCST000322 Genome-wide genotyping array 2759 2015-05-23 21326860 Tsai FJ 2011-02-04 PLoS One www.ncbi.nlm.nih.gov/pubmed/21326860 Identification of novel susceptibility Loci for kawasaki disease in a Han chinese population by a genome-wide association study. Kawasaki disease 250 Han Chinese ancestry cases, 446 Han Chinese ancestry controls 208 Han Chinese ancestry cases, 366 Han Chinese ancestry controls Affymetrix [723638] 2 mucocutaneous lymph node syndrome http://www.ebi.ac.uk/efo/EFO_0004246 GCST000962 Genome-wide genotyping array 696 2008-06-16 17052657 Fung HC 2006-09-28 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/17052657 Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data. Parkinson's disease 267 European ancestry cases, 270 European ancestry controls NA Illumina [408803] 3 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST000005 Genome-wide genotyping array 537 2008-06-16 17478679 Helgadottir A 2007-05-03 Science www.ncbi.nlm.nih.gov/pubmed/17478679 A common variant on chromosome 9p21 affects the risk of myocardial infarction. Myocardial infarction 1,607 European ancestry cases, 6,728 European ancestry controls 2,980 European ancestry cases, 6,309 European ancestry controls Illumina [305953] 1 myocardial infarction http://www.ebi.ac.uk/efo/EFO_0000612 GCST000030 Genome-wide genotyping array 8335 2009-06-16 19488044 Smith EN 2009-06-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/19488044 Genome-wide association study of bipolar disorder in European American and African American individuals. Bipolar disorder 1,001 European ancestry cases, 1,033 European ancestry controls, 345 African American cases, 670 African American controls 1,550 European ancestry individuals from 250 families, 1,263 European ancestry cases, 431 European ancestry controls Affymetrix [702044] 1 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST000417 Genome-wide genotyping array 3049 2010-03-07 20159113 Jakkula E 2010-02-12 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/20159113 Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene. Multiple sclerosis 68 Finland founder cases, 136 Finland founder controls 83 Finland founder cases, 365 Finland founder controls 3,285 European ancestry cases, 6,379 European ancestry controls, 1,202 cases, 3,399 controls Illumina [297343] 2 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST000593 Genome-wide genotyping array 204 2010-03-12 20172861 Okada Y 2010-02-18 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/20172861 Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count. Neutrophil count 5,771 Japanese ancestry individuals 1,894 Japanese ancestry individuals Illumina [486091] 2 neutrophil count http://www.ebi.ac.uk/efo/EFO_0004833 GCST000600 Genome-wide genotyping array 5771 2009-10-15 19197348 Lowe JK 2009-02-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/19197348 Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae. Quantitative traits 2,906 Kosraen individuals NA Affymetrix [408775] 33 waist circumference, total cholesterol measurement, body fat distribution, C-reactive protein measurement, body mass index, high density lipoprotein cholesterol measurement, body height, diastolic blood pressure, triglyceride measurement, systolic blood pressure, low density lipoprotein cholesterol measurement, body weight, thyroid stimulating hormone measurement http://www.ebi.ac.uk/efo/EFO_0004342, http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0004341, http://www.ebi.ac.uk/efo/EFO_0004458, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612, http://www.ebi.ac.uk/efo/EFO_0004339, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004611, http://www.ebi.ac.uk/efo/EFO_0004338, http://www.ebi.ac.uk/efo/EFO_0004748 GCST000337 Genome-wide genotyping array 2906 2009-01-14 19084217 Benyamin B 2008-12-17 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/19084217 Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels. Iron status biomarkers 411 European ancestry individuals from 150 families NA Affymetrix [100846] 3 iron biomarker measurement http://www.ebi.ac.uk/efo/EFO_0004461 GCST000302 Genome-wide genotyping array 561 2009-01-14 19084217 Benyamin B 2008-12-17 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/19084217 Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels. Iron status biomarkers 459 European ancestry twin pairs NA Illumina [315887] 24 iron biomarker measurement http://www.ebi.ac.uk/efo/EFO_0004461 GCST000301 Genome-wide genotyping array 459 2008-06-16 16252231 Maraganore DM 2005-09-09 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/16252231 High-resolution whole-genome association study of Parkinson disease. Parkinson's disease 381 European ancestry cases, 363 European ancestry controls, 62 cases,79 controls, 1 Asian ancestry control from 443 sibships 269 European ancestry cases, 272 European ancestry controls, 62 cases, 60 controls, 1 Asian ancestry case Perlegen [198345] 1 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST000002 Genome-wide genotyping array 1329 2011-01-15 21150874 McDonough CW 2010-12-08 Kidney Int www.ncbi.nlm.nih.gov/pubmed/21150874 A genome-wide association study for diabetic nephropathy genes in African Americans. Type 2 diabetes nephropathy 965 African American cases, 1,029 African American controls 709 African American cases, 690 African American controls Affymetrix [832357] 5 diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0000401 GCST000909 Genome-wide genotyping array 1994 2009-04-22 19343178 Soranzo N 2009-04-03 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/19343178 Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size. Height 12,611 European ancestry individuals 7,187 European ancestry individuals Illumina [229216] 20 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST000372 Genome-wide genotyping array 12611 2009-06-17 19503088 Gregersen PK 2009-06-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19503088 REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis. Rheumatoid arthritis 2,418 European ancestry cases, 4,504 European ancestry controls 2,604 cases, 2,882 controls Illumina [278502] 5 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST000420 Genome-wide genotyping array 6922 2009-04-16 19349983 Kamatani Y 2009-04-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19349983 A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians. Hepatitis B 179 Japanese ancestry cases, 934 Japanese ancestry controls 1,599 Japanese ancestry cases, 2,821 Japanese ancestry controls, 308 Thai ancestry cases, 546 Thai ancestry controls Illumina [499544] 1 hepatitis B virus infection http://www.ebi.ac.uk/efo/EFO_0004197 GCST000375 Genome-wide genotyping array 1113 2011-01-03 21044949 Yang J 2010-11-02 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21044949 ELF1 is associated with systemic lupus erythematosus in Asian populations. Systemic lupus erythematosus 612 Chinese ancestry cases, 1,160 Chinese ancestry controls 2,090 Chinese ancestry cases, 1,981 Chinese ancestry controls, 462 Thai ancestry cases, 951 Thai ancestry controls Illumina [513108] 1 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST000858 Genome-wide genotyping array 1772 2013-11-09 20592726 Chen SH 2010-06-30 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/20592726 Genetic variations in GRIA1 on chromosome 5q33 related to asparaginase hypersensitivity. Asparaginase hypersensitivity in acute lymphoblastic leukemia 211 European ancestry child cases, 40 Black child cases, 46 Hispanic child cases, 4 Asian ancestry child cases, 21 child cases 99 European ancestry child cases, 33 Black child cases, 24 Hispanic child cases, 2 Asian ancestry child cases, 5 child cases Affymetrix [364033] 1 asparaginase hypersensitivity http://www.ebi.ac.uk/efo/EFO_0004881 GCST000715 Genome-wide genotyping array 322 2011-05-13 21497890 Orange JS 2011-04-15 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/21497890 Genome-wide association identifies diverse causes of common variable immunodeficiency. Common variable immunodeficiency 179 European ancestry cases, 1,917 European ancestry controls 109 European ancestry cases, 1,114 European ancestry controls Illumina [610000] 0 Common variable immunodeficiency http://www.orpha.net/ORDO/Orphanet_1572 GCST001039 Genome-wide genotyping array 2096 2015-05-26 21314694 Kendler KS 2011-02-11 Alcohol Clin Exp Res www.ncbi.nlm.nih.gov/pubmed/21314694 Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample. Alcohol dependence 2,357 European ancestry individuals, 812 African American individuals NA Affymetrix [NR] 3 alcohol dependence http://www.ebi.ac.uk/efo/EFO_0003829 GCST000977 Genome-wide genotyping array 3169 2012-01-24 21254220 Jiang Y 2011-02-01 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/21254220 Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder. Bipolar disorder 1,868 European ancestry cases, 2,938 European ancestry controls NA Affymetrix [NR] 24 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST000961 Genome-wide genotyping array 4806 2011-05-25 21505073 Terao C 2011-04-19 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21505073 The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population. Rheumatoid arthritis 1,247 Japanese ancestry cases, 1,486 Japanese ancestry controls 4,168 Japanese ancestry cases, 5,003 Japanese ancestry controls Illumina [241523] 3 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST001042 Genome-wide genotyping array 2733 2009-06-01 19448622 Sulem P 2009-05-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19448622 Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche. Menarche (age at onset) 15,297 European ancestry female individuals 10,040 European ancestry female individuals Illumina [304226] 1 age at menarche http://www.ebi.ac.uk/efo/EFO_0004703 GCST000400 Genome-wide genotyping array 15297 2015-05-28 21316860 Velders FP 2011-02-11 Psychoneuroendocrinology www.ncbi.nlm.nih.gov/pubmed/21316860 Genetics of cortisol secretion and depressive symptoms: a candidate gene and genome wide association approach. Cortisol secretion 1,711 European ancestry individuals 2,836 European ancestry individuals Illumina [530683] 0 cortisol secretion measurement http://www.ebi.ac.uk/efo/EFO_0004642 GCST000978 Genome-wide genotyping array 1711 2009-05-19 19430479 Levy D 2009-05-10 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19430479 Genome-wide association study of blood pressure and hypertension. Hypertension 29,136 European ancestry individuals 34,433 European ancestry individuals Affymetrix, Illumina [2533153] (imputed) 4 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST000398 Genome-wide genotyping array 29136 2009-05-19 19430479 Levy D 2009-05-10 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19430479 Genome-wide association study of blood pressure and hypertension. Systolic blood pressure 29,136 European ancestry individuals 34,433 European ancestry individuals Affymetrix, Illumina [2533153] (imputed) 7 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST000393 Genome-wide genotyping array 29136 2009-05-19 19430479 Levy D 2009-05-10 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19430479 Genome-wide association study of blood pressure and hypertension. Diastolic blood pressure 29,136 European ancestry individuals 34,433 European ancestry individuals Affymetrix, Illumina [2533153] (imputed) 7 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST000396 Genome-wide genotyping array 29136 2009-09-29 19736353 Ising M 2009-09-01 Arch Gen Psychiatry www.ncbi.nlm.nih.gov/pubmed/19736353 A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression. Response to antidepressant treatment 700 European ancestry cases 832 European ancestry cases, 366 European ancestry controls Illumina [389251] 0 response to antidepressant http://purl.obolibrary.org/obo/GO_0036276 GCST000471 Genome-wide genotyping array 700 2010-12-16 21082022 Padmanabhan S 2010-10-28 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21082022 Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. Hypertension 1,621 extreme cases, 1,699 controls 19,845 extreme cases, 16,541 controls Illumina [521220] (imputed) 1 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST000849 Genome-wide genotyping array 3320 2010-07-12 20548946 Ramdas WD 2010-06-10 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/20548946 A genome-wide association study of optic disc parameters. Vertical cup-disc ratio 7,360 European ancestry individuals 4,455 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 9 optic disc size measurement http://www.ebi.ac.uk/efo/EFO_0004832 GCST000700 Genome-wide genotyping array 7360 2010-07-12 20548946 Ramdas WD 2010-06-10 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/20548946 A genome-wide association study of optic disc parameters. Optic disc parameters 7,360 European ancestry individuals 4,455 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 3 optic disc size measurement http://www.ebi.ac.uk/efo/EFO_0004832 GCST000699 Genome-wide genotyping array 7360 2010-10-15 20877300 Perroud N 2010-09-28 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/20877300 Genome-wide association study of increasing suicidal ideation during antidepressant treatment in the GENDEP project. Suicidal ideation 706 European ancestry individuals NA Illumina [539199] 4 suicidal ideation http://www.ebi.ac.uk/efo/EFO_0004320 GCST000816 Genome-wide genotyping array 706 2009-06-14 19454037 Arnett DK 2009-05-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/19454037 Genome-wide association study identifies single-nucleotide polymorphism in KCNB1 associated with left ventricular mass in humans: the HyperGEN Study. Left ventricular mass 101 European ancestry cases, 101 European ancestry controls 704 European ancestry individuals, 1,467 African American individuals Affymetrix [96258] 2 left ventricular structural measurement http://www.ebi.ac.uk/efo/EFO_0008205 GCST000407 Genome-wide genotyping array 202 2009-09-30 19749757 Tanaka Y 2009-09-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19749757 Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C. Response to hepatitis C treatment 64 Japanese ancestry responders, 78 Japanese ancestry non-responders 122 Japanese ancestry responders, 50 Japanese ancestry non-responders Affymetrix [621220] 1 chronic hepatitis C virus infection http://www.ebi.ac.uk/efo/EFO_0004220 GCST000486 Genome-wide genotyping array 142 2010-03-17 20147318 Qi L 2010-02-22 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/20147318 Genetic variants in ABO blood group region, plasma soluble E-selectin levels and risk of type 2 diabetes. E-selectin levels 501 European ancestry type 2 diabetes female cases, 504 European ancestry female controls 518 European ancestry female individuals Affymetrix [721316] 1 e-selectin measurement http://www.ebi.ac.uk/efo/EFO_0004575 GCST000606 Genome-wide genotyping array 1007 2013-11-29 23722424 Rietveld CA 2013-05-30 Science www.ncbi.nlm.nih.gov/pubmed/23722424 GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Educational attainment up to 101,069 European ancestry individuals 25,490 European ancestry individuals Affymetrix, Illumina, Perlegen [up to 2309290] (imputed) 9 self reported educational attainment http://www.ebi.ac.uk/efo/EFO_0004784 GCST002045 Genome-wide genotyping array 101069 2013-12-01 23722424 Rietveld CA 2013-05-30 Science www.ncbi.nlm.nih.gov/pubmed/23722424 GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Educational attainment (college completion) up to 126,559 European ancestry individuals NA Affymetrix, Illumina, Perlegen [up to 23218963] (imputed) 1 self reported educational attainment http://www.ebi.ac.uk/efo/EFO_0004784 GCST002047 Genome-wide genotyping array 126559 2019-08-09 23722424 Rietveld CA 2013-05-30 Science www.ncbi.nlm.nih.gov/pubmed/23722424 GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Educational attainment (years of education) up to 126,559 European ancestry individuals NA Affymetrix, Illumina, Perlegen [up to 23218963] (imputed) 3 self reported educational attainment http://www.ebi.ac.uk/efo/EFO_0004784 GCST008396 Genome-wide genotyping array 126559 2010-03-06 20169177 Yang W 2010-02-12 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/20169177 Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus. Systemic lupus erythematosus 314 Chinese ancestry cases, 1,484 Chinese ancestry controls 2,630 Chinese ancestry cases, 2,155 Chinese ancestry controls, 314 Thai ancestry cases, 519 Thai ancestry controls Illumina [514221] 2 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST000592 Genome-wide genotyping array 1798 2010-03-23 20171287 Stein JL 2010-02-17 Neuroimage www.ncbi.nlm.nih.gov/pubmed/20171287 Voxelwise genome-wide association study (vGWAS). Brain structure 740 European ancestry individuals NA Illumina [448293] 19 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST000597 Genome-wide genotyping array 740 2009-04-03 19330030 Thomas G 2009-03-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19330030 A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Breast cancer 1,145 European ancestry cases, 1,142 European ancestry controls 8,625 European ancestry cases, 9,657 European ancestry controls Illumina [528173] 6 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST000365 Genome-wide genotyping array 2287 2009-05-19 19419973 Sanna S 2009-05-06 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/19419973 Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia. Bilirubin levels 4,300 Sardinian individuals 1,860 Sardinian individuals, 832 Old Order Amish individuals Affymetrix [362129] 3 bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004570 GCST000388 Genome-wide genotyping array 4300 2008-11-12 18834626 Dehghan A 2008-10-01 Lancet www.ncbi.nlm.nih.gov/pubmed/18834626 Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study. Urate levels 11,847 European ancestry individuals 11,024 European ancestry individuals, 3,843 African American individuals Affymetrix, Illumina [up to 530683] 3 urate measurement http://www.ebi.ac.uk/efo/EFO_0004531 GCST000242 Genome-wide genotyping array 11847 2009-12-28 20010834 Repapi E 2009-12-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20010834 Genome-wide association study identifies five loci associated with lung function. Pulmonary function 20,288 European ancestry individuals up to 54,276 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 7 pulmonary function measurement http://www.ebi.ac.uk/efo/EFO_0003892 GCST000544 Genome-wide genotyping array 20288 2009-12-28 19961619 Castro-Giner F 2009-12-06 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/19961619 A pooling-based genome-wide analysis identifies new potential candidate genes for atopy in the European Community Respiratory Health Survey (ECRHS). Atopy 75 European ancestry atopy and asthma cases, 75 European ancestry atopy only cases, 75 European ancestry controls 429 European ancestry atopy cases, 222 European ancestry controls Illumina [NR] 1 atopy http://www.ebi.ac.uk/efo/EFO_0002686 GCST000540 Genome-wide genotyping array 225 2013-04-30 21519539 Cho SC 2011-02-25 Psychiatry Investig www.ncbi.nlm.nih.gov/pubmed/21519539 Genome-wide association scan of korean autism spectrum disorders with language delay: a preliminary study. Autism spectrum disorders (language delay) 42 Korean ancestry male cases and their parental controls NA Affymetrix [331095] 0 autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0003756 GCST000991 Genome-wide genotyping array 42 2009-02-26 19165232 Otowa T 2009-01-23 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/19165232 Genome-wide association study of panic disorder in the Japanese population. Panic disorder 200 Japanese ancestry cases, 200 Japanese ancestry controls NA Affymetrix [253903] 17 panic disorder http://www.ebi.ac.uk/efo/EFO_0004262 GCST000320 Genome-wide genotyping array 400 2008-11-12 18849994 Hillmer AM 2008-10-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18849994 Susceptibility variants for male-pattern baldness on chromosome 20p11. Male-pattern baldness 296 European ancestry cases, 347 European ancestry controls 319 European ancestry cases, 234 European ancestry controls Illumina [531695] 1 androgenetic alopecia http://www.ebi.ac.uk/efo/EFO_0004191 GCST000251 Genome-wide genotyping array 643 2011-05-25 21502966 Weber F 2011-04-19 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/21502966 Single-nucleotide polymorphisms in HLA- and non-HLA genes associated with the development of antibodies to interferon-β therapy in multiple sclerosis patients. Response to interferon beta therapy 178 European ancestry antibody-positive individuals, 184 European ancestry antibody-negative individuals 350 European ancestry antibody-positive individuals, 468 European ancestry antibody-negative individuals Illumina [~ 317000] 2 response to interferon beta http://purl.obolibrary.org/obo/GO_0035456 GCST001043 Genome-wide genotyping array 362 2009-12-28 20023658 Mangold E 2009-12-20 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20023658 Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate. Orofacial clefts 399 European ancestry cases, 1,318 European ancestry controls 655 European ancestry triads Illumina [521288] 6 cleft lip http://www.ebi.ac.uk/efo/EFO_0003959 GCST000547 Genome-wide genotyping array 1717 2009-02-28 19219042 Zheng W 2009-02-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19219042 Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1. Breast cancer 1,505 Chinese ancestry cases, 1,522 Chinese ancestry controls 5,026 Chinese ancestry cases, 2,476 Chinese ancestry controls, 1,591 European ancestry cases, 1,466 European ancestry controls Affymetrix [up to 607728] 1 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST000343 Genome-wide genotyping array 3027 2010-01-08 20012890 Ronald A 2009-12-13 Behav Genet www.ncbi.nlm.nih.gov/pubmed/20012890 A genome-wide association study of social and non-social autistic-like traits in the general population using pooled DNA, 500 K SNP microarrays and both community and diagnosed autism replication samples. Social and non-social autistic-like traits 1,462 European ancestry individuals 3,494 European ancestry individuals Affymetrix [up to 435457] 0 behavior or behavioral disorder measurement http://www.ebi.ac.uk/efo/EFO_0004782 GCST000543 Genome-wide genotyping array 1462 2009-07-24 19578179 Teichert M 2009-07-04 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/19578179 A genome-wide association study of acenocoumarol maintenance dosage. Acenocoumarol maintenance dosage 1,451 European ancestry individuals 287 individuals Illumina [~ 550000] 4 response to anticoagulant http://purl.obolibrary.org/obo/GO_0061476 GCST000436 Genome-wide genotyping array 1451 2012-01-25 20686565 Teslovich TM 2010-08-05 Nature www.ncbi.nlm.nih.gov/pubmed/20686565 Biological, clinical and population relevance of 95 loci for blood lipids. Triglycerides 96,598 European ancestry individuals NA Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) 32 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST000758 Genome-wide genotyping array 96598 2012-01-25 20686565 Teslovich TM 2010-08-05 Nature www.ncbi.nlm.nih.gov/pubmed/20686565 Biological, clinical and population relevance of 95 loci for blood lipids. Cholesterol, total 100,184 European ancestry individuals NA Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) 52 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST000760 Genome-wide genotyping array 100184 2012-01-25 20686565 Teslovich TM 2010-08-05 Nature www.ncbi.nlm.nih.gov/pubmed/20686565 Biological, clinical and population relevance of 95 loci for blood lipids. LDL cholesterol 95,454 European ancestry individuals NA Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) 37 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST000759 Genome-wide genotyping array 95454 2012-01-25 20686565 Teslovich TM 2010-08-05 Nature www.ncbi.nlm.nih.gov/pubmed/20686565 Biological, clinical and population relevance of 95 loci for blood lipids. HDL cholesterol 99,900 European ancestry individuals NA Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) 47 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST000755 Genome-wide genotyping array 99900 2011-01-16 21151128 Chen ZJ 2010-12-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21151128 Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3. Polycystic ovary syndrome 744 Han Chinese ancestry cases, 895 Han Chinese ancestry controls 3,338 Han Chinese ancestry cases, 5,792 Han Chinese ancestry controls Affymetrix [611633] 5 polycystic ovary syndrome http://www.ebi.ac.uk/efo/EFO_0000660 GCST000914 Genome-wide genotyping array 1639 2011-02-23 21228123 Ochi H 2011-01-12 J Gen Virol www.ncbi.nlm.nih.gov/pubmed/21228123 IL-28B predicts response to chronic hepatitis C therapy--fine-mapping and replication study in Asian populations. Response to hepatitis C treatment 2,101 East Asian ancestry cases, 282 Japanese ancestry controls NA Illumina [510537] 1 chronic hepatitis C virus infection http://www.ebi.ac.uk/efo/EFO_0004220 GCST000944 Genome-wide genotyping array 2383 2011-02-03 21211648 Ege MJ 2011-01-01 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/21211648 Gene-environment interaction for childhood asthma and exposure to farming in Central Europe. Asthma or atopy (farm exposure interaction) 850 European asthmatic child cases, 348 European atopic child cases, 510 European child controls NA Illumina [2500000] (imputed) 0 farm exposure measurement, asthma http://www.ebi.ac.uk/efo/EFO_0008362, http://www.ebi.ac.uk/efo/EFO_0000270 GCST000934 Genome-wide genotyping array 1708 2010-11-23 20932310 Han MR 2010-10-08 BMC Neurol www.ncbi.nlm.nih.gov/pubmed/20932310 Genome-wide association reveals genetic effects on human Aβ42 and τ protein levels in cerebrospinal fluids: a case control study. Cerebrospinal T-tau levels 172 European ancestry Alzheimer's disease cases, 109 European ancestry mild cognitive impairment cases, 109 European ancestry controls NA Illumina [498205] 5 t-tau measurement http://www.ebi.ac.uk/efo/EFO_0004760 GCST000826 Genome-wide genotyping array 390 2010-11-23 20932310 Han MR 2010-10-08 BMC Neurol www.ncbi.nlm.nih.gov/pubmed/20932310 Genome-wide association reveals genetic effects on human Aβ42 and τ protein levels in cerebrospinal fluids: a case control study. Cerebrospinal P-tau181p levels 172 European ancestry Alzheimer's disease cases, 109 European ancestry mild cognitive impairment cases, 109 European ancestry controls NA Illumina [498205] 5 p-tau measurement http://www.ebi.ac.uk/efo/EFO_0004763 GCST000825 Genome-wide genotyping array 390 2010-11-23 20932310 Han MR 2010-10-08 BMC Neurol www.ncbi.nlm.nih.gov/pubmed/20932310 Genome-wide association reveals genetic effects on human Aβ42 and τ protein levels in cerebrospinal fluids: a case control study. Cerebrospinal fluid AB1-42 levels 172 European ancestry Alzheimer's disease cases, 109 European ancestry mild cognitive impairment cases, 109 European ancestry controls NA Illumina [498205] 7 beta-amyloid 1-42 measurement http://www.ebi.ac.uk/efo/EFO_0004670 GCST000827 Genome-wide genotyping array 390 2011-01-15 21203500 Lauc G 2010-12-23 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21203500 Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation. N-glycan levels 2,559 European ancestry individuals NA Illumina [~ 300000] 8 N-glycan measurement http://www.ebi.ac.uk/efo/EFO_0004999 GCST000925 Genome-wide genotyping array 2559 2010-05-24 20418890 Tobacco and Genetics Consortium 2010-04-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20418890 Genome-wide meta-analyses identify multiple loci associated with smoking behavior. Smoking behavior Up to 74,035 European ancestry individuals Up to 68,988 participants Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 5 smoking behavior http://www.ebi.ac.uk/efo/EFO_0004318 GCST000666 Genome-wide genotyping array 74035 2013-11-15 23704328 Fatemifar G 2013-05-23 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23704328 Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances. Primary tooth development (number of teeth) 11,513 European ancestry individuals NA Illumina [2446724] (imputed) 11 odontogenesis http://purl.obolibrary.org/obo/GO_0042476 GCST002031 Genome-wide genotyping array 11513 2013-11-15 23704328 Fatemifar G 2013-05-23 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23704328 Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances. Primary tooth development (time to first tooth eruption) 11,118 European ancestry individuals NA Illumina [2446724] (imputed) 13 tooth eruption http://purl.obolibrary.org/obo/GO_0044691 GCST002030 Genome-wide genotyping array 11118 2009-05-11 19404256 Wang K 2009-04-28 Nature www.ncbi.nlm.nih.gov/pubmed/19404256 Common genetic variants on 5p14.1 associate with autism spectrum disorders. Autism 3,101 European ancestry individuals from 780 families, 1,204 European ancestry cases, 6,491 European ancestry controls 1,390 European ancestry individuals from 447 families, 108 European ancestry cases, 540 European ancestry controls Illumina [474019] 1 autism http://www.ebi.ac.uk/efo/EFO_0003758 GCST000382 Genome-wide genotyping array 11576 2008-10-14 18760390 Huyghe JR 2008-09-12 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/18760390 Genome-wide SNP-based linkage scan identifies a locus on 8q24 for an age-related hearing impairment trait. Hearing impairment 1,081 European ancestry individuals from 200 sibships NA Affymetrix [169154] 0 hearing loss http://www.ebi.ac.uk/efo/EFO_0004238 GCST000230 Genome-wide genotyping array 1281 2008-09-10 17903303 O'Donnell CJ 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903303 Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study. Subclinical atherosclerosis traits (other) Up to 984 individuals NA Affymetrix [70897] 8 cardiovascular disease biomarker measurement http://www.ebi.ac.uk/efo/EFO_0005278 GCST000087 Genome-wide genotyping array 984 2008-09-10 17903297 Seshadri S 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903297 Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study. Volumetric brain MRI 705 European ancestry individuals NA Affymetrix [70897] 5 volumetric brain MRI http://www.ebi.ac.uk/efo/EFO_0004868 GCST000088 Genome-wide genotyping array 705 2008-09-10 17903297 Seshadri S 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903297 Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study. Cognitive test performance 694 European ancestry individuals NA Affymetrix [70897] 14 neuropsychological test http://www.ebi.ac.uk/efo/EFO_0003926 GCST000098 Genome-wide genotyping array 694 2008-09-10 17903303 O'Donnell CJ 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903303 Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study. Coronary artery calcification Up to 678 individuals NA Affymetrix [70897] 3 coronary artery calcification http://www.ebi.ac.uk/efo/EFO_0004723 GCST000097 Genome-wide genotyping array 678 2008-09-10 17903306 Newton-Cheh C 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903306 Genome-wide association study of electrocardiographic and heart rate variability traits: the Framingham Heart Study. Heart rate variability traits 747 European ancestry individuals from 307 families NA Affymetrix [70897] 2 heart rate http://www.ebi.ac.uk/efo/EFO_0004326 GCST000086 Genome-wide genotyping array 1054 2009-09-28 17903306 Newton-Cheh C 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903306 Genome-wide association study of electrocardiographic and heart rate variability traits: the Framingham Heart Study. Electrocardiographic traits 1,951 European ancestry individuals from 355 families NA Affymetrix [70897] 2 electrocardiography http://www.ebi.ac.uk/efo/EFO_0004327 GCST000111 Genome-wide genotyping array 2306 2009-07-10 19571808 Stefansson H 2009-07-01 Nature www.ncbi.nlm.nih.gov/pubmed/19571808 Common variants conferring risk of schizophrenia. Schizophrenia 2,663 European ancestry cases, 13,498 European ancestry controls 10,282 European ancestry cases, 21,093 European ancestry controls Illumina [314868] 7 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST000435 Genome-wide genotyping array 16161 2009-07-13 19571811 Purcell SM 2009-07-01 Nature www.ncbi.nlm.nih.gov/pubmed/19571811 Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Schizophrenia 3,322 European ancestry cases, 3,587 European ancestry controls 4,692 European ancestry cases, 15,493 European ancestry controls Affymetrix [739995] 4 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST000434 Genome-wide genotyping array 6909 2010-05-10 20364137 Yasuno K 2010-04-04 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20364137 Genome-wide association study of intracranial aneurysm identifies three new risk loci. Intracranial aneurysm 2,780 European ancestry cases, 12,515 European ancestry controls 3,111 Japanese ancestry cases, 1,666 Japanese ancestry controls Illumina [831534] (imputed) 6 brain aneurysm http://www.ebi.ac.uk/efo/EFO_0003870 GCST000646 Genome-wide genotyping array 15295 2009-07-12 19578366 Wrensch M 2009-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19578366 Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility. Glioma (high-grade) 692 European ancestry cases, 3,992 European ancestry controls 176 cases, 174 controls Illumina [326506] 3 central nervous system cancer http://www.ebi.ac.uk/efo/EFO_0000326 GCST000440 Genome-wide genotyping array 4684 2010-05-26 20442857 Suchindran S 2010-04-29 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/20442857 Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study. Lipoprotein-associated phospholipase A2 activity and mass 6,668 European ancestry individuals NA Affymetrix [360811] 5 lipoprotein-associated phospholipase A(2) measurement http://www.ebi.ac.uk/efo/EFO_0004746 GCST000671 Genome-wide genotyping array 6668 2008-09-12 18073375 Duggan D 2007-12-19 J Natl Cancer Inst www.ncbi.nlm.nih.gov/pubmed/18073375 Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB2IP. Prostate cancer 1,235 European ancestry cases, 1,599 European ancestry controls 1,032 European ancestry cases, 571 European ancestry controls, 210 African American cases, 346 African American controls Affymetrix, Illumina [60275] 0 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST000128 Genome-wide genotyping array 2834 2010-05-18 20395239 Macgregor S 2010-04-15 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/20395239 Genome-wide association identifies ATOH7 as a major gene determining human optic disc size. Optic nerve measurement (cup area) 1,368 European ancestry twins from 666 families 848 European ancestry twins from 531 families Illumina [~ 2740000] (imputed) 9 optic disc size measurement http://www.ebi.ac.uk/efo/EFO_0004832 GCST000659 Genome-wide genotyping array 2034 2010-05-18 20395239 Macgregor S 2010-04-15 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/20395239 Genome-wide association identifies ATOH7 as a major gene determining human optic disc size. Optic nerve measurement (rim area) 1,368 European ancestry twins from 666 families 848 European ancestry twins from 531 families Illumina [~ 2740000] (imputed) 6 optic disc size measurement http://www.ebi.ac.uk/efo/EFO_0004832 GCST000658 Genome-wide genotyping array 2034 2010-05-18 20395239 Macgregor S 2010-04-15 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/20395239 Genome-wide association identifies ATOH7 as a major gene determining human optic disc size. Optic nerve measurement (disc area) 1,368 European ancestry twins from 666 families 848 European ancestry twins from 531 families Illumina [~ 2740000] (imputed) 7 optic disc size measurement http://www.ebi.ac.uk/efo/EFO_0004832 GCST000657 Genome-wide genotyping array 2034 2014-07-09 20395239 Macgregor S 2010-04-15 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/20395239 Genome-wide association identifies ATOH7 as a major gene determining human optic disc size. Optic nerve measurement (cup-to-disc ratio) 1,368 European ancestry twins from 666 families 848 European ancestry twins from 531 families Illumina [~ 2740000] (imputed) 4 optic disc size measurement http://www.ebi.ac.uk/efo/EFO_0004832 GCST000655 Genome-wide genotyping array 2034 2010-06-02 20453838 Turnbull C 2010-05-09 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20453838 Genome-wide association study identifies five new breast cancer susceptibility loci. Breast cancer 3,659 European ancestry cases, 4,897 European ancestry controls 12,576 European ancestry cases, 12,223 European ancestry controls Illumina [582886] 13 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST000678 Genome-wide genotyping array 8556 2010-05-23 20418485 Ahn J 2010-04-23 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/20418485 Genome-wide association study of circulating vitamin D levels. Vitamin D levels 4,501 European ancestry individuals 2,221 European ancestry individuals Affymetrix, Illumina [593253] (imputed) 3 vitamin D measurement http://www.ebi.ac.uk/efo/EFO_0004631 GCST000664 Genome-wide genotyping array 4501 2015-05-23 24556642 Zeng Z 2014-02-18 Caries Res www.ncbi.nlm.nih.gov/pubmed/24556642 Genome-wide association study of primary dentition pit-and-fissure and smooth surface caries. Pit-and-Fissure caries 979 European ancestry individuals NA Illumina [1216074] (imputed) 14 pit and fissure surface dental caries http://www.ebi.ac.uk/efo/EFO_0006338 GCST002358 Genome-wide genotyping array 979 2014-10-21 24556642 Zeng Z 2014-02-18 Caries Res www.ncbi.nlm.nih.gov/pubmed/24556642 Genome-wide association study of primary dentition pit-and-fissure and smooth surface caries. Smooth-surface caries 1006 European ancestry individuals NA Illumina [1216189] (imputed) 31 smooth surface dental caries http://www.ebi.ac.uk/efo/EFO_0006339 GCST002361 Genome-wide genotyping array 1006 2011-05-11 21473668 Fliers EA 2011-04-07 World J Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/21473668 Genome-wide association study of motor coordination problems in ADHD identifies genes for brain and muscle function. Attention deficit hyperactivity disorder motor coordination 890 European ancestry children 296 European ancestry children Perlegen [384401] 1 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST001030 Genome-wide genotyping array 890 2013-04-24 21483845 McLaren CE 2011-03-31 PLoS One www.ncbi.nlm.nih.gov/pubmed/21483845 Genome-wide association study identifies genetic loci associated with iron deficiency. Iron status biomarkers 336 European ancestry iron deficiency cases, 343 European ancestry controls 71 European ancestry iron deficiency cases, 161 European ancestry controls Illumina [331060] 9 iron biomarker measurement http://www.ebi.ac.uk/efo/EFO_0004461 GCST001021 Genome-wide genotyping array 679 2013-04-24 21483845 McLaren CE 2011-03-31 PLoS One www.ncbi.nlm.nih.gov/pubmed/21483845 Genome-wide association study identifies genetic loci associated with iron deficiency. Iron deficiency 336 European ancestry cases, 343 European ancestry controls 71 European ancestry cases, 161 European ancestry controls Illumina [331060] 1 anemia (phenotype) http://www.ebi.ac.uk/efo/EFO_0004272 GCST001020 Genome-wide genotyping array 679 2009-04-01 19198611 Tregouet DA 2009-02-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19198611 Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. Coronary heart disease 1,926 European ancestry cases, 2,938 European ancestry controls 7,073 European ancestry cases, 7,325 European ancestry controls Affymetrix [~ 500000] 2 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST000341 Genome-wide genotyping array 4864 2010-03-17 20215924 Liu X 2010-01-01 J Am Acad Child Adolesc Psychiatry www.ncbi.nlm.nih.gov/pubmed/20215924 A genome-wide association study of amygdala activation in youths with and without bipolar disorder. Functional MRI 36 European ancestry BD cases, 21 European ancestry controls, 1 African American BD case, 5 African American controls, 2 BD cases, 3 controls NA Illumina [104043] 2 amygdala reactivity measurement http://www.ebi.ac.uk/efo/EFO_0004550 GCST000556 Genome-wide genotyping array 68 2011-03-04 21223598 Wineinger NE 2011-01-11 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/21223598 Genome-wide joint SNP and CNV analysis of aortic root diameter in African Americans: the HyperGEN study. Aortic root size 1,086 African American individuals NA Affymetrix [NR] 7 aortic root size http://www.ebi.ac.uk/efo/EFO_0005037 GCST000943 Genome-wide genotyping array 1086 2009-12-28 20018961 Zhang FR 2009-12-16 N Engl J Med www.ncbi.nlm.nih.gov/pubmed/20018961 Genomewide association study of leprosy. Leprosy 706 Han Chinese ancestry cases, 1,225 Han Chinese ancestry controls 3,254 Chinese ancestry cases, 5,955 Chinese ancestry controls Illumina [491883] 6 leprosy http://www.ebi.ac.uk/efo/EFO_0001054 GCST000546 Genome-wide genotyping array 1931 2010-01-07 20011104 Richards JB 2009-12-05 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/20011104 A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. Adiponectin levels 8,531 European ancestry individuals 6,202 European ancestry individuals Affymetrix, Illumina [~ 2200000] (imputed) 3 adiponectin measurement http://www.ebi.ac.uk/efo/EFO_0004502 GCST000538 Genome-wide genotyping array 8531 2011-02-22 21216879 Kaplan RC 2011-01-07 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21216879 A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3. Insulin-like growth factors 10,280 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 8 IGFBP-3 measurement http://www.ebi.ac.uk/efo/EFO_0004626 GCST000937 Genome-wide genotyping array 10280 2008-09-12 17903304 Larson MG 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903304 Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes. Major CVD 142 cases and 1,203 controls from 310 families NA Affymetrix [70897] 1 cardiovascular disease http://www.ebi.ac.uk/efo/EFO_0000319 GCST000093 Genome-wide genotyping array 1655 2008-10-14 17903304 Larson MG 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903304 Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes. Atrial fibrillation 151 cases and 1,190 controls from 310 families NA Affymetrix [70897] 3 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST000109 Genome-wide genotyping array 1651 2009-09-28 17903304 Larson MG 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903304 Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes. Heart failure 75 cases and 1,272 controls from 310 families NA Affymetrix [70897] 1 heart failure http://www.ebi.ac.uk/efo/EFO_0003144 GCST000104 Genome-wide genotyping array 1657 2010-07-12 20581827 Voight BF 2010-06-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20581827 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Type 2 diabetes 8,130 European ancestry cases, 38,987 European ancestry controls Up to 34,412 European ancestry cases, 59,925 European ancestry controls Affymetrix, Illumina [2426886] (imputed) 26 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST000712 Genome-wide genotyping array 47117 2009-02-28 19185284 Ferrucci L 2009-01-29 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/19185284 Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study. Carotenoid and tocopherol levels 1,191 European ancestry individuals 2,540 European ancestry individuals, 211 individuals Illumina [~ 500451] 2 carotenoid measurement, tocopherol measurement http://www.ebi.ac.uk/efo/EFO_0004737, http://www.ebi.ac.uk/efo/EFO_0004738 GCST000324 Genome-wide genotyping array 1191 2008-09-10 17903296 Kiel DP 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903296 Genome-wide association with bone mass and geometry in the Framingham Heart Study. Bone mineral density Up to 1,141 individuals from 241 families NA Affymetrix [70897] 8 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST000092 Genome-wide genotyping array 1382 2008-09-10 17903296 Kiel DP 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903296 Genome-wide association with bone mass and geometry in the Framingham Heart Study. Hip geometry Up to 1,094 individuals from 241 families NA Affymetrix [70897] 16 hip geometry http://www.ebi.ac.uk/efo/EFO_0004685 GCST000101 Genome-wide genotyping array 1335 2011-02-22 21212386 Arnett DK 2011-01-06 Circ Res www.ncbi.nlm.nih.gov/pubmed/21212386 Genetic variation in NCAM1 contributes to left ventricular wall thickness in hypertensive families. Cardiac muscle measurement 1,258 Black individuals 989 Black individuals, 1,316 European ancestry individuals Affymetrix [872242] 3 cardiovascular measurement, left ventricular hypertrophy http://www.ebi.ac.uk/efo/EFO_0004298, http://www.ebi.ac.uk/efo/EFO_0003896 GCST000936 Genome-wide genotyping array 1258 2011-01-18 21177773 Moyer AM 2010-12-22 Toxicol Sci www.ncbi.nlm.nih.gov/pubmed/21177773 Acetaminophen-NAPQI hepatotoxicity: a cell line model system genome-wide association study. Response to acetaminophen (hepatotoxicity) 60 European ancestry lymphoblastoid cell lines, 56 African American lymphoblastoid cell lines, 60 Han Chinese American lymphoblastoid cell lines NA Affymetrix, Illumina [1348864] 5 response to acetaminophen http://purl.obolibrary.org/obo/GO_1901554 GCST000924 Genome-wide genotyping array 176 2009-02-25 19182806 Stefansson H 2009-02-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19182806 Variant in the sequence of the LINGO1 gene confers risk of essential tremor. Essential tremor 452 European ancestry cases, 14,378 European ancestry controls 301 European ancestry cases, 1,419 European ancestry controls Illumina [305624] 1 essential tremor http://www.ebi.ac.uk/efo/EFO_0003108 GCST000329 Genome-wide genotyping array 14830 2014-11-21 24795349 Saxena R 2014-05-03 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/24795349 Genome-wide association study identifies variants in casein kinase II (CSNK2A2) to be associated with leukocyte telomere length in a Punjabi Sikh diabetic cohort. Telomere length 842 Punjabi Sikh ancestry type 2 diabetes cases, 774 Punjabi Sikh ancestry controls 1,108 Punjabi Sikh ancestry type 2 diabetes cases, 1,289 Punjabi Sikh ancestry controls, 2,952 European ancestry myocardial infarction cases and healthy controls, 10,033 European ancestry individuals Illumina [5904251] (imputed) 2 telomere length http://www.ebi.ac.uk/efo/EFO_0004505 GCST002437 Genome-wide genotyping array 1618 2011-03-29 21297633 Anderson CA 2011-02-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21297633 Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Ulcerative colitis 6,687 European ancestry cases, 19,718 European ancestry controls 9,628 European ancestry cases, 12,917 European ancestry controls Affymetrix, Illumina [~ 1100000] (imputed) 47 ulcerative colitis http://www.ebi.ac.uk/efo/EFO_0000729 GCST000964 Genome-wide genotyping array 26405 2009-06-19 19508968 Zhai G 2009-06-08 J Med Genet www.ncbi.nlm.nih.gov/pubmed/19508968 A genome-wide association study suggests that a locus within the ataxin 2 binding protein 1 gene is associated with hand osteoarthritis: the Treat-OA consortium. Osteoarthritis 1,804 European ancestry individuals 3,266 European ancestry individuals Illumina [up to 535188] 0 osteoarthritis http://www.ebi.ac.uk/efo/EFO_0002506 GCST000421 Genome-wide genotyping array 1804 2008-06-16 18204447 Kozyrev SV 2008-01-20 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18204447 Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus. Systemic lupus erythematosus 279 European ancestry cases, 515 European ancestry controls 1,757 European ancestry cases, 1,540 European ancestry controls Affymetrix [85042] 1 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST000143 Genome-wide genotyping array 794 2015-05-27 21294900 Charles BA 2011-02-04 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/21294900 A genome-wide association study of serum uric acid in African Americans. Uric acid levels 1,017 African American individuals NA Affymetrix [2366856] (imputed) 12 uric acid measurement http://www.ebi.ac.uk/efo/EFO_0004761 GCST000963 Genome-wide genotyping array 1017 2009-03-31 19193627 Chio A 2009-02-04 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/19193627 A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis 537 European ancestry cases, 1,984 European ancestry controls 2,741 European ancestry cases, 2,875 European ancestry controls Illumina [545066] 0 amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0000253 GCST000333 Genome-wide genotyping array 2521 2012-01-20 22179738 Lai HM 2011-12-16 Rheumatology (Oxford) www.ncbi.nlm.nih.gov/pubmed/22179738 Gout and type 2 diabetes have a mutual inter-dependent effect on genetic risk factors and higher incidences. Gout 20 Han Chinese ancestry male gout cases, 42 Han Chinese ancestry male controls NA Illumina [479403] 36 gout http://www.ebi.ac.uk/efo/EFO_0004274 GCST001356 Genome-wide genotyping array 62 2008-12-01 18952825 Johansson A 2008-10-24 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/18952825 Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis. Height 3,925 European ancestry individuals Up to 39,859 European ancestry individuals, Up to 1,148 African American individuals Illumina [NR] 1 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST000254 Genome-wide genotyping array 3925 2008-06-16 18264098 Gudmundsson J 2008-02-10 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18264098 Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer. Prostate cancer 1,854 European ancestry cases, 21,372 European ancestry controls 8,239 European ancestry cases, 7,590 European ancestry controls Illumina [310520] 2 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST000153 Genome-wide genotyping array 23226 2009-03-01 19198609 Kathiresan S 2009-02-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19198609 Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Myocardial infarction (early onset) 2,967 European ancestry cases, 3,075 European ancestry controls 9,746 European ancestry cases, 9,746 European ancestry controls Affymetrix [~ 2500000] (imputed) 9 myocardial infarction http://www.ebi.ac.uk/efo/EFO_0000612 GCST000340 Genome-wide genotyping array 6042 2011-12-20 22116939 Guo Y 2011-11-24 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22116939 Two-stage genome-wide association study identifies variants in CAMSAP1L1 as susceptibility loci for epilepsy in Chinese. Epilepsy 504 Han Chinese ancestry cases, 2,947 Han Chinese ancestry controls 583 Han Chinese ancestry cases, 497 Han Chinese ancestry controls Illumina [461024] 1 epilepsy http://www.ebi.ac.uk/efo/EFO_0000474 GCST001329 Genome-wide genotyping array 3451 2008-12-01 19011631 Houlston RS 2008-11-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19011631 Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. Colorectal cancer 1,902 European ancestry cases, 1,929 European ancestry controls 18,284 European ancestry cases, 18,926 European ancestry controls Illumina [up to 548586] 4 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST000270 Genome-wide genotyping array 3831 2008-06-16 18372903 Zeggini E 2008-03-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18372903 Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Type 2 diabetes 4,549 European ancestry cases, 5,579 European ancestry controls 24,194 European ancestry cases, 55,598 European ancestry controls Affymetrix, Illumina [2202892] (imputed) 16 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST000167 Genome-wide genotyping array 10128 2008-12-01 18997786 Bilguvar K 2008-11-09 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18997786 Susceptibility loci for intracranial aneurysm in European and Japanese populations. Intracranial aneurysm 1,580 European ancestry cases, 6,276 European ancestry controls 495 Japanese ancestry cases, 676 Japanese ancestry controls Illumina [289271] 4 brain aneurysm http://www.ebi.ac.uk/efo/EFO_0003870 GCST000262 Genome-wide genotyping array 7856 2009-02-25 19181680 Timpson NJ 2009-01-30 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/19181680 Common variants in the region around Osterix are associated with bone mineral density and growth in childhood. Bone mineral density 1,418 European ancestry children, 134 European ancestry adult individuals 3,875 European ancestry children Illumina [up to 315807] 0 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST000325 Genome-wide genotyping array 1552 2009-01-15 19079260 Thorleifsson G 2008-12-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19079260 Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Weight 72,598 European ancestry individuals, 1,160 African American individuals Up to 11,036 European ancestry individuals, 32,615 individuals Illumina [305846] 17 body weight http://www.ebi.ac.uk/efo/EFO_0004338 GCST000299 Genome-wide genotyping array 73758 2009-01-15 19079260 Thorleifsson G 2008-12-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19079260 Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Body mass index 72,598 European ancestry individuals, 1,160 African American individuals Up to 11,036 European ancestry individuals, 32,615 individuals Illumina [305846] 14 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST000296 Genome-wide genotyping array 73758 2008-12-09 18985386 Pankratz N 2008-11-06 Hum Genet www.ncbi.nlm.nih.gov/pubmed/18985386 Genomewide association study for susceptibility genes contributing to familial Parkinson disease. Parkinson's disease (familial) 1,119 European ancestry cases, 1,127 European ancestry controls NA Illumina [328189] 1 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST000261 Genome-wide genotyping array 2246 2015-04-22 21305692 Belmonte Mahon P 2011-02-08 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/21305692 Genome-wide association analysis of age at onset and psychotic symptoms in bipolar disorder. Bipolar disorder (age of onset and psychotic symptoms) 2,836 European ancestry cases, 2,744 European ancestry controls 3,916 European cases, 5,112 controls Affymetrix, Illumina [2373895] (imputed) 2 age at onset, psychotic symptoms, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0004847, http://www.ebi.ac.uk/efo/EFO_0005940, http://www.ebi.ac.uk/efo/EFO_0000289 GCST000969 Genome-wide genotyping array 5580 2010-01-19 20009918 Shrestha S 2010-01-01 AIDS www.ncbi.nlm.nih.gov/pubmed/20009918 A genome-wide association study of carotid atherosclerosis in HIV-infected men. Carotid atherosclerosis in HIV infection 177 European ancestry individuals NA Illumina [311194] 7 common carotid intimal medial thickness, internal carotid intimal medial thickness, carotid artery disease http://www.ebi.ac.uk/efo/EFO_0004860, http://www.ebi.ac.uk/efo/EFO_0005053, http://www.ebi.ac.uk/efo/EFO_0003781 GCST000555 Genome-wide genotyping array 177 2008-06-16 17603485 Gudmundsson J 2007-07-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/17603485 Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Prostate cancer 1,501 European ancestry cases, 11,290 European ancestry controls 1,992 European ancestry cases, 3,058 European ancestry controls Illumina [310520] 2 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST000050 Genome-wide genotyping array 12791 2011-03-02 21273288 Del Greco M F 2011-01-27 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21273288 Genome-wide association analysis and fine mapping of NT-proBNP level provide novel insight into the role of the MTHFR-CLCN6-NPPA-NPPB gene cluster. Natriuretic peptide levels 1,325 European ancestry individuals 1,746 European ancestry individuals Illumina [~ 2500000] (imputed) 3 NT-proBNP measurement http://www.ebi.ac.uk/efo/EFO_0004745 GCST000957 Genome-wide genotyping array 1325 2008-09-15 17903295 Lunetta KL 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903295 Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study. Aging traits 1,345 individuals from 330 families NA Affymetrix [70897] 10 age at menopause, aging, exercise test, age at death http://www.ebi.ac.uk/efo/EFO_0004704, http://purl.obolibrary.org/obo/GO_0007568, http://www.ebi.ac.uk/efo/EFO_0004328, http://www.ebi.ac.uk/efo/EFO_0005056 GCST000096 Genome-wide genotyping array 1675 2008-09-10 17903295 Lunetta KL 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903295 Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study. Morbidity-free survival 558 individuals NA Affymetrix [70897] 5 disease free survival http://www.ebi.ac.uk/efo/EFO_0000409 GCST000103 Genome-wide genotyping array 558 2008-06-16 17603472 Gudbjartsson DF 2007-07-01 Nature www.ncbi.nlm.nih.gov/pubmed/17603472 Variants conferring risk of atrial fibrillation on chromosome 4q25. Atrial fibrillation/atrial flutter 550 European ancestry cases, 4,476 European ancestry controls 3,030 European ancestry cases, 14,780 European ancestry controls, 333 Han Chinese ancestry cases, 2,836 Han Chinese ancestry controls Illumina [316515] 2 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST000051 Genome-wide genotyping array 5026 2010-01-28 20072603 Guo Y 2010-01-08 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/20072603 Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis. Osteoporosis 350 Han Chinese ancestry cases, 350 Han Chinese ancestry controls 390 Han Chinese ancestry cases, 516 Han Chinese ancestry controls Affymetrix [281533] 1 osteoporosis http://www.ebi.ac.uk/efo/EFO_0003882 GCST000560 Genome-wide genotyping array 700 2011-03-28 21270382 Baik I 2011-01-26 Am J Clin Nutr www.ncbi.nlm.nih.gov/pubmed/21270382 Genome-wide association studies identify genetic loci related to alcohol consumption in Korean men. Alcohol consumption 1,721 Korean ancestry male individuals 1,113 Korean ancestry male individuals Affymetrix [315914] 4 alcohol drinking http://www.ebi.ac.uk/efo/EFO_0004329 GCST000954 Genome-wide genotyping array 1721 2010-02-05 20070850 Edwards TL 2010-01-13 Ann Hum Genet www.ncbi.nlm.nih.gov/pubmed/20070850 Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease. Parkinson's disease 1,752 European ancestry cases, 1,745 European ancestry controls NA Illumina [495715] (imputed) 6 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST000567 Genome-wide genotyping array 3497 2015-05-23 21208937 Pichler I 2011-01-04 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21208937 Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels. Iron status biomarkers Up to 5,633 European ancestry individuals Up to 3,457 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 5 iron biomarker measurement http://www.ebi.ac.uk/efo/EFO_0004461 GCST000935 Genome-wide genotyping array 5633 2013-04-04 23328707 Tin A 2013-01-16 Nephrol Dial Transplant www.ncbi.nlm.nih.gov/pubmed/23328707 Genome-wide significant locus of beta-trace protein, a novel kidney function biomarker, identified in European and African Americans. Beta-trace protein levels 6,720 European ancestry individuals 1,734 African American individuals Affymetrix [~ 2500000] (imputed) 1 renal system measurement http://www.ebi.ac.uk/efo/EFO_0004742 GCST001825 Genome-wide genotyping array 6720 2009-11-12 19850125 Kim HJ 2009-10-19 Neurobiol Dis www.ncbi.nlm.nih.gov/pubmed/19850125 Common CYP7A1 promoter polymorphism associated with risk of neuromyelitis optica. Neuromyelitis optica 53 Korean ancestry cases, 240 Korean ancestry controls 37 Korean ancestry cases Illumina [288025] 0 neuromyelitis optica http://www.ebi.ac.uk/efo/EFO_0004256 GCST000508 Genome-wide genotyping array 293 2010-06-14 20512145 Bei JX 2010-05-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20512145 A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci. Nasopharyngeal carcinoma 1,583 Chinese ancestry cases, 1,894 Chinese ancestry controls 3,507 Chinese ancestry cases, 3,063 Chinese ancestry controls, 284 Chinese ancestry trios Illumina [464328] 7 nasopharyngeal neoplasm http://www.ebi.ac.uk/efo/EFO_0004252 GCST000687 Genome-wide genotyping array 3477 2012-01-27 22199011 Murabito JM 2011-12-23 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/22199011 Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Ankle-brachial index 38,376 European ancestry individuals, 2,133 Erasmus Rucphen individuals, 1,183 Old Order Amish individuals 16,717 European ancestry individuals Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 2 ankle brachial index http://www.ebi.ac.uk/efo/EFO_0003912 GCST001361 Genome-wide genotyping array 41692 2015-04-23 19875614 Paterson AD 2009-10-29 Diabetes www.ncbi.nlm.nih.gov/pubmed/19875614 A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose. Glycemic control in type 1 diabetes (HbA1c) 667 European ancestry conventional treatment cases, 637 European ancestry intensive treatment cases 1,382 European ancestry cases Affymetrix, Illumina [2518578] (imputed) 0 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST000516 Genome-wide genotyping array 1304 2008-09-17 18327257 Vitart V 2008-03-09 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18327257 SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout. Urate levels 794 European ancestry individuals 706 European ancestry individuals Illumina [308140] 1 urate measurement http://www.ebi.ac.uk/efo/EFO_0004531 GCST000160 Genome-wide genotyping array 794 2013-11-29 23727862 Savage SA 2013-06-02 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23727862 Genome-wide association study identifies two susceptibility loci for osteosarcoma. Osteosarcoma 694 European ancestry cases, 2,703 European ancestry controls 247 European ancestry cases, 550 European ancestry controls Illumina [698968] 6 osteosarcoma http://www.ebi.ac.uk/efo/EFO_0000637 GCST002056 Genome-wide genotyping array 3397 2009-07-24 19587794 Nolte IM 2009-07-09 PLoS One www.ncbi.nlm.nih.gov/pubmed/19587794 Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies. QT interval 3,558 European ancestry individuals 29,527 European ancestry individuals Affymetrix, Illumina [~ 2399142] (imputed) 2 QT interval http://www.ebi.ac.uk/efo/EFO_0004682 GCST000444 Genome-wide genotyping array 3558 2009-10-06 19779542 Nakanishi H 2009-09-25 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/19779542 A genome-wide association analysis identified a novel susceptible locus for pathological myopia at 11q24.1. Myopia (pathological) 297 Japanese ancestry cases, 934 Japanese ancestry controls 533 Japanese ancestry cases, 977 Japanese ancestry controls Illumina [411777] 1 pathological myopia http://www.ebi.ac.uk/efo/EFO_0004207 GCST000491 Genome-wide genotyping array 1231 2008-06-16 18311140 Hunt KA 2008-03-02 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18311140 Newly identified genetic risk variants for celiac disease related to the immune response. Celiac disease 767 European ancestry cases, 1,422 European ancestry controls 1,643 European ancestry cases, 3,406 European ancestry controls Illumina [310605] 8 celiac disease http://www.ebi.ac.uk/efo/EFO_0001060 GCST000157 Genome-wide genotyping array 2189 2009-09-04 19648919 Song H 2009-08-02 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19648919 A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. Ovarian cancer 1,817 European ancestry cases, 2,353 European ancestry controls 6,944 European ancestry cases, 9,477 European ancestry controls Illumina [up to 2000000] (imputed) 1 ovarian carcinoma http://www.ebi.ac.uk/efo/EFO_0001075 GCST000455 Genome-wide genotyping array 4170 2008-09-17 18325910 Liu YJ 2008-03-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/18325910 Genome-wide association scans identified CTNNBL1 as a novel gene for obesity. Obesity 1,000 European ancestry individuals 896 European ancestry cases, 2,916 European ancestry controls Affymetrix [379319] 0 obesity http://www.ebi.ac.uk/efo/EFO_0001073 GCST000159 Genome-wide genotyping array 1000 2013-11-15 23698163 Gong J 2013-05-21 Nutrients www.ncbi.nlm.nih.gov/pubmed/23698163 Genome-wide association study of serum selenium concentrations. Serum selenium levels 582 European ancestry individuals 621 European ancestry individuals Illumina [2474333] 4 serum selenium measurement http://www.ebi.ac.uk/efo/EFO_0005266 GCST002028 Genome-wide genotyping array 582 2009-12-03 19902172 Palmer ND 2009-11-10 Diabetologia www.ncbi.nlm.nih.gov/pubmed/19902172 Candidate loci for insulin sensitivity and disposition index from a genome-wide association analysis of Hispanic participants in the Insulin Resistance Atherosclerosis (IRAS) Family Study. Insulin-related traits 229 Hispanic individuals from 34 families 814 Hispanic family members Illumina [309200] 0 insulin measurement http://www.ebi.ac.uk/efo/EFO_0004467 GCST000526 Genome-wide genotyping array 263 2013-02-27 23284291 Hancock DB 2012-12-20 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/23284291 Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. Pulmonary function (smoking interaction) 50,047 European ancestry individuals NA NR [~ 2500000] (imputed) 53 pulmonary function measurement, smoking behaviour measurement http://www.ebi.ac.uk/efo/EFO_0003892, http://www.ebi.ac.uk/efo/EFO_0005671 GCST001784 Genome-wide genotyping array 50047 2010-05-06 20385826 Neale BM 2010-04-12 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/20385826 Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC). Age-related macular degeneration 979 cases, 1,709 controls 868 European ancestry cases, 410 European ancestry controls, 4,921 cases, 3,824 controls Affymetrix [632932] 11 age-related macular degeneration http://www.ebi.ac.uk/efo/EFO_0001365 GCST000653 Genome-wide genotyping array 2688 2008-09-25 18794855 Kiemeney LA 2008-09-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18794855 Sequence variant on 8q24 confers susceptibility to urinary bladder cancer. Urinary bladder cancer 1,803 European ancestry cases, 34,336 European ancestry controls 2,165 European ancestry cases, 3,800 European ancestry controls Illumina [302140] 2 bladder carcinoma http://www.ebi.ac.uk/efo/EFO_0000292 GCST000231 Genome-wide genotyping array 36139 2010-03-22 20175129 Zhao LJ 2009-12-11 J Bone Miner Res www.ncbi.nlm.nih.gov/pubmed/20175129 Genome-wide association study for femoral neck bone geometry. Femoral neck bone geometry 987 European ancestry individuals 1,488 European ancestry individuals, 2,118 Chinese ancestry individuals Affymetrix [379319] 0 femoral neck bone geometry http://www.ebi.ac.uk/efo/EFO_0004511 GCST000541 Genome-wide genotyping array 987 2010-07-04 20548944 Hsu YH 2010-06-10 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/20548944 An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits. Osteoporosis-related phenotypes 2,038 European ancestry female individuals, 1,531 European ancestry male individuals 5,595 European ancestry female individuals, 2,126 European ancestry male individuals Affymetrix [433510] 7 osteoporosis http://www.ebi.ac.uk/efo/EFO_0003882 GCST000698 Genome-wide genotyping array 3569 2010-05-24 20418889 Liu JZ 2010-04-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20418889 Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Smoking behavior 41,150 European ancestry individuals 120,516 European ancestry individuals Affymetrix, Illumina [NR] (imputed) 1 smoking behavior http://www.ebi.ac.uk/efo/EFO_0004318 GCST000668 Genome-wide genotyping array 41150 2008-12-09 18997785 Aulchenko YS 2008-11-09 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18997785 Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis. Multiple sclerosis 45 European ancestry cases,195 European ancestry controls 1,316 European ancestry cases, 1,423 European ancestry controls, 1,318 cases and 1,507 controls from 756 families Affymetrix [~ 250000] 1 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST000263 Genome-wide genotyping array 240 2009-04-01 19303062 Tanaka T 2009-03-18 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/19303062 Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations. Folate pathway vitamin levels 2,934 European ancestry individuals 686 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 5 vitamin B measurement, vitamin B12 measurement, vitamin B6 measurement http://www.ebi.ac.uk/efo/EFO_0004843, http://www.ebi.ac.uk/efo/EFO_0004620, http://www.ebi.ac.uk/efo/EFO_0004621 GCST000358 Genome-wide genotyping array 2934 2010-06-22 20526339 Quan C 2010-06-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20526339 Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC. Vitiligo 1,117 Han Chinese ancestry cases, 1,429 Han Chinese ancestry controls 6,623 East Asian ancestry cases, 10,740 East Asian ancestry controls Illumina [493909] 4 Vitiligo http://www.ebi.ac.uk/efo/EFO_0004208 GCST000692 Genome-wide genotyping array 2546 2009-11-04 19798445 Hicks AA 2009-10-02 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/19798445 Genetic determinants of circulating sphingolipid concentrations in European populations. Sphingolipid levels 4,110 European ancestry individuals NA Illumina [318237] 5 sphingolipid measurement http://www.ebi.ac.uk/efo/EFO_0004622 GCST000493 Genome-wide genotyping array 4110 2010-03-29 20304703 Li Y 2010-03-19 Lancet Oncol www.ncbi.nlm.nih.gov/pubmed/20304703 Genetic variants and risk of lung cancer in never smokers: a genome-wide association study. Lung cancer 364 European ancestry cases, 364 European ancestry controls, 13 cases, 13 controls 446 European ancestry cases, 853 European ancestry controls, 65 cases, 154 controls Illumina [331918] 1 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST000633 Genome-wide genotyping array 754 2011-04-11 21378988 Coronary Artery Disease (C4D) Genetics Consortium 2011-03-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21378988 A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease. Coronary heart disease 8,424 European ancestry cases, 7,268 European ancestry controls, 6,996 South Asian ancestry cases, 7,794 South Asian ancestry controls 18,049 European ancestry cases, 16,357 European ancestry controls, 3,359 South Asian ancestry cases, 2,828 South Asian ancestry controls Illumina [574919] 19 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST000999 Genome-wide genotyping array 30482 2011-04-13 21423239 Willour VL 2011-03-25 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/21423239 A genome-wide association study of attempted suicide. Suicide attempts in bipolar disorder 1,201 European and unknown ancestry attempters, 1,497 European and unknown ancestry non-attempters 1,295 attempters, 1,822 non-attempters Affymetrix, Illumina [2408051] (imputed) 3 attempted suicide http://www.ebi.ac.uk/efo/EFO_0004321 GCST001015 Genome-wide genotyping array 2698 2013-05-02 18514160 Arnaud-Lopez L 2008-06-01 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/18514160 Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function. Thyroid stimulating hormone levels 4,300 Sardinian indivduals 1,164 European ancestry individuals, 1,136 Old Order Amish individuals, 1,858 Sardinian individuals Affymetrix [362129] 1 thyroid function http://www.ebi.ac.uk/efo/EFO_0004296 GCST000199 Genome-wide genotyping array 4300 2011-01-11 21150878 Ferreira MA 2010-12-08 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/21150878 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia. Asthma 986 European ancestry cases, 1,846 European ancestry controls 391 European ancestry cases, 213 European ancestry controls Illumina [~ 2380000] (imputed) 1 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST000910 Genome-wide genotyping array 2832 2011-04-13 21441570 Grassi MA 2011-03-26 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21441570 Genome-wide meta-analysis for severe diabetic retinopathy. Diabetic retinopathy 973 European ancestry cases, 1,856 European ancestry controls NA Affymetrix, Illumina [2543887] (imputed) 19 diabetic retinopathy http://www.ebi.ac.uk/efo/EFO_0003770 GCST001017 Genome-wide genotyping array 2829 2011-01-03 21184583 Zlojutro M 2010-11-02 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/21184583 Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. Event-related brain oscillations 431 European ancestry alcohol dependence cases, 340 European ancestry controls, 209 African American alcohol dependence cases, 84 African American controls 683 alcohol dependence cases and 412 controls from multiplex families Illumina [951071] 3 event-related brain oscillation http://www.ebi.ac.uk/efo/EFO_0004358 GCST000857 Genome-wide genotyping array 1064 2011-05-11 21483023 Wu X 2011-04-11 J Natl Cancer Inst www.ncbi.nlm.nih.gov/pubmed/21483023 Genome-wide association study of survival in non-small cell lung cancer patients receiving platinum-based chemotherapy. Response to platinum-based chemotherapy in non-small-cell lung cancer 327 European ancestry individuals 735 European ancestry individuals Illumina [307260] 1 response to platinum based chemotherapy http://www.ebi.ac.uk/efo/EFO_0004647 GCST001035 Genome-wide genotyping array 327 2011-04-11 21378990 Schunkert H 2011-03-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21378990 Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Coronary heart disease 22,233 European ancestry cases, 64,762 European ancestry controls 56,682 European ancestry cases and controls Affymetrix, Illumina [~ 2300000] (imputed) 30 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST000998 Genome-wide genotyping array 86995 2011-01-14 21130836 Luciano M 2010-12-03 Biol Psychol www.ncbi.nlm.nih.gov/pubmed/21130836 Whole genome association scan for genetic polymorphisms influencing information processing speed. Information processing speed Up to 4,039 European ancestry individuals NA Illumina [~ 610000] 25 information processing speed http://www.ebi.ac.uk/efo/EFO_0004363 GCST000905 Genome-wide genotyping array 4039 2010-10-07 20876611 Wu Y 2010-09-27 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/20876611 Genome-wide association study for adiponectin levels in Filipino women identifies CDH13 and a novel uncommon haplotype at KNG1-ADIPOQ. Adiponectin levels 1,776 Filipino ancestry female individuals 1,774 Filipino ancestry offspring Affymetrix [2073674] (imputed) 3 adiponectin measurement http://www.ebi.ac.uk/efo/EFO_0004502 GCST000812 Genome-wide genotyping array 1776 2010-11-15 20932654 Kerns SL 2010-10-05 Int J Radiat Oncol Biol Phys www.ncbi.nlm.nih.gov/pubmed/20932654 Genome-wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men after radiotherapy for prostate cancer. Erectile dysfunction and prostate cancer treatment 27 African American cases, 52 African American controls NA Affymetrix [512497] 23 response to radiation, prostate carcinoma, erectile dysfunction http://purl.obolibrary.org/obo/GO_0009314, http://www.ebi.ac.uk/efo/EFO_0001663, http://www.ebi.ac.uk/efo/EFO_0004234 GCST000824 Genome-wide genotyping array 79 2011-01-03 21041692 Denny JC 2010-11-01 Circulation www.ncbi.nlm.nih.gov/pubmed/21041692 Identification of genomic predictors of atrioventricular conduction: using electronic medical records as a tool for genome science. Atrioventricular conduction 2,334 European ancestry individuals NA Illumina [514999] 5 heart function measurement http://www.ebi.ac.uk/efo/EFO_0004311 GCST000852 Genome-wide genotyping array 2334 2013-06-18 23703922 Li WD 2013-01-02 Obesity (Silver Spring) www.ncbi.nlm.nih.gov/pubmed/23703922 A genome wide association study of plasma uric acid levels in obese cases and never-overweight controls. Uric acid levels 487 European ancestry obese individuals, 472 non-obese individuals NA Illumina [~ 550000] 6 uric acid measurement http://www.ebi.ac.uk/efo/EFO_0004761 GCST001801 Genome-wide genotyping array 959 2010-09-15 20700443 Meyer TE 2010-08-05 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/20700443 Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels. Magnesium levels 15,366 European ancestry individuals 8,463 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 9 magnesium measurement http://www.ebi.ac.uk/efo/EFO_0004845 GCST000756 Genome-wide genotyping array 15366 2009-01-12 19060906 Kathiresan S 2008-12-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19060906 Common variants at 30 loci contribute to polygenic dyslipidemia. HDL cholesterol 19,840 European ancestry individuals Up to 20,623 European ancestry individuals Affymetrix, Illumina [~ 2600000] (imputed) 14 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST000290 Genome-wide genotyping array 19840 2009-01-14 19060906 Kathiresan S 2008-12-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19060906 Common variants at 30 loci contribute to polygenic dyslipidemia. LDL cholesterol 19,840 European ancestry individuals Up to 20,623 European ancestry individuals Affymetrix, Illumina [~ 2600000] (imputed) 11 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST000287 Genome-wide genotyping array 19840 2009-01-12 19060906 Kathiresan S 2008-12-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19060906 Common variants at 30 loci contribute to polygenic dyslipidemia. Triglycerides 19,840 European ancestry individuals Up to 20,623 European ancestry individuals Affymetrix, Illumina [~ 2600000] (imputed) 11 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST000286 Genome-wide genotyping array 19840 2009-03-31 19260141 Zemunik T 2009-02-01 Croat Med J www.ncbi.nlm.nih.gov/pubmed/19260141 Genome-wide association study of biochemical traits in Korcula Island, Croatia. Biochemical measures 898 Korculan (founder/genetic isolate) individuals NA Illumina [316730] 17 serum albumin measurement, total cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, fibrinogen measurement, uric acid measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004535, http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0004611, http://www.ebi.ac.uk/efo/EFO_0004623, http://www.ebi.ac.uk/efo/EFO_0004761, http://www.ebi.ac.uk/efo/EFO_0004612 GCST000328 Genome-wide genotyping array 898 2010-09-16 20694014 Thye T 2010-08-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20694014 Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2. Tuberculosis 2,237 Sub-Saharan African ancestry cases, 3,122 Sub-Saharan African ancestry controls 1,462 Sub-Saharan African ancestry cases, 4,604 Sub-Saharan African ancestry controls Affymetrix [> 333754] (imputed) 14 Tuberculosis http://www.orpha.net/ORDO/Orphanet_3389 GCST000764 Genome-wide genotyping array 5359 2010-12-09 20972440 Houlston RS 2010-10-24 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20972440 Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33. Colorectal cancer 3,334 European ancestry cases, 4,628 European ancestry controls 14,851 European ancestry cases, 15,569 European ancestry controls Illumina [up to 550000] (imputed) 5 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST000843 Genome-wide genotyping array 7962 2013-05-14 21618603 Beaty TH 2011-05-26 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/21618603 Evidence for gene-environment interaction in a genome wide study of nonsyndromic cleft palate. Orofacial clefts (maternal alcohol consumption interaction) 272 European ancestry trios, 259 Asian ancestry trios, 19 African ancestry or other ancestry trios NA Illumina [~ 498000] 2 alcohol consumption measurement, Orofacial clefting syndrome, cleft lip http://www.ebi.ac.uk/efo/EFO_0007878, http://www.orpha.net/ORDO/Orphanet_139039, http://www.ebi.ac.uk/efo/EFO_0003959 GCST001082 Genome-wide genotyping array 550 2011-07-07 21665994 Kutalik Z 2011-06-10 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21665994 Genome-wide association study identifies two loci strongly affecting transferrin glycosylation. Alcohol consumption (transferrin glycosylation) 5,181 European ancestry individuals 2,284 European ancestry individauls Affymetrix [390631] (imputed) 6 alcohol drinking http://www.ebi.ac.uk/efo/EFO_0004329 GCST001103 Genome-wide genotyping array 5181 2008-07-22 18360741 Butcher LM 2008-03-25 Behav Genet www.ncbi.nlm.nih.gov/pubmed/18360741 The nature of nurture: a genomewide association scan for family chaos. Environmental confusion in the home 469 European ancestry children from low chaos families, 369 European ancestry children from high chaos families 3,529 European ancestry children Affymetrix [117062] 0 CHAOS measure http://www.ebi.ac.uk/efo/EFO_0004779 GCST000166 Genome-wide genotyping array 838 2009-01-16 19010793 Baranzini SE 2008-11-14 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/19010793 Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Multiple sclerosis 978 European ancestry cases, 883 European ancestry controls NA Illumina [551642] 10 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST000269 Genome-wide genotyping array 1861 2009-01-16 19010793 Baranzini SE 2008-11-14 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/19010793 Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Multiple sclerosis (age of onset) 978 European ancestry cases, 883 European ancestry controls NA Illumina [551642] 8 multiple sclerosis, age at onset http://www.ebi.ac.uk/efo/EFO_0003885, http://www.ebi.ac.uk/efo/EFO_0004847 GCST000267 Genome-wide genotyping array 1861 2009-01-16 19010793 Baranzini SE 2008-11-14 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/19010793 Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Normalized brain volume 753 European ancestry cases, 883 European ancestry controls NA Illumina [551642] 5 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST000268 Genome-wide genotyping array 1636 2009-01-16 19010793 Baranzini SE 2008-11-14 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/19010793 Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Brain lesion load 791 European ancestry cases, 883 European ancestry controls NA Illumina [551642] 4 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST000265 Genome-wide genotyping array 1674 2009-01-16 19010793 Baranzini SE 2008-11-14 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/19010793 Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Multiple sclerosis (severity) 794 European ancestry cases, 883 European ancestry controls NA Illumina [551642] 11 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST000266 Genome-wide genotyping array 1677 2011-07-20 21658281 Aouizerat BE 2011-06-10 BMC Cardiovasc Disord www.ncbi.nlm.nih.gov/pubmed/21658281 GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease. Sudden cardiac arrest 88 European ancestry cases, 517 European ancestry controls NA Affymetrix [319222] 6 sudden cardiac arrest http://www.ebi.ac.uk/efo/EFO_0004278 GCST001102 Genome-wide genotyping array 605 2011-07-20 21658281 Aouizerat BE 2011-06-10 BMC Cardiovasc Disord www.ncbi.nlm.nih.gov/pubmed/21658281 GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease. Sudden cardiac arrest 88 European ancestry cases, 517 European ancestry controls NA Affymetrix [319222] 7 sudden cardiac arrest http://www.ebi.ac.uk/efo/EFO_0004278 GCST001104 Genome-wide genotyping array 605 2011-07-20 21658281 Aouizerat BE 2011-06-10 BMC Cardiovasc Disord www.ncbi.nlm.nih.gov/pubmed/21658281 GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease. Sudden cardiac arrest 88 European ancestry cases, 517 European ancestry controls NA Affymetrix [319222] 36 sudden cardiac arrest http://www.ebi.ac.uk/efo/EFO_0004278 GCST001099 Genome-wide genotyping array 605 2009-01-12 19079261 Willer CJ 2008-12-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19079261 Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Body mass index 32,387 European ancestry individuals 59,082 European ancestry individuals Affymetrix, Illumina [2399588] (imputed) 11 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST000298 Genome-wide genotyping array 32387 2012-10-19 21102463 Franke A 2010-11-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21102463 Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Crohn's disease 6,333 European ancestry cases, 15,056 European ancestry controls 15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios Affymetrix, Illumina [953241] (imputed) 71 Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000384 GCST000879 Genome-wide genotyping array 21389 2013-11-15 23708190 Hu Z 2013-05-26 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23708190 A genome-wide association study identifies two risk loci for congenital heart malformations in Han Chinese populations. Congenital heart malformation 945 Han Chinese ancestry cases, 1,246 Han Chinese ancestry controls 2,160 Han Chinese ancestry cases, 3,866 Han Chinese ancestry controls Illumina [708275] 2 congenital heart malformation http://www.ebi.ac.uk/efo/EFO_0005269 GCST002036 Genome-wide genotyping array 2191 2013-08-20 20848476 Haritunians T 2010-11-01 Inflamm Bowel Dis www.ncbi.nlm.nih.gov/pubmed/20848476 Genetic predictors of medically refractory ulcerative colitis. Ulcerative colitis 324 European ancestry medically refractory ulcerative colitis cases, 537 European ancestry non-medically refractory ulcerative colitis cases, 2,601 European ancestry controls NA Illumina [313720] 10 ulcerative colitis http://www.ebi.ac.uk/efo/EFO_0000729 GCST000853 Genome-wide genotyping array 3462 2009-09-28 17903307 Wilk JB 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903307 Framingham Heart Study genome-wide association: results for pulmonary function measures. Mean forced vital capacity from 2 exams Up to 1,222 individuals NA Affymetrix [70897] 2 vital capacity http://www.ebi.ac.uk/efo/EFO_0004312 GCST000099 Genome-wide genotyping array 1222 2008-09-10 17903307 Wilk JB 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903307 Framingham Heart Study genome-wide association: results for pulmonary function measures. Pulmonary function Up to 1,222 individuals NA Affymetrix [70897] 10 pulmonary function measurement http://www.ebi.ac.uk/efo/EFO_0003892 GCST000106 Genome-wide genotyping array 1222 2008-07-01 18391951 Gudbjartsson DF 2008-04-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18391951 Many sequence variants affecting diversity of adult human height. Height 30,968 European ancestry individuals 8,541 European ancestry individuals Affymetrix, Illumina [up to 304226] 52 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST000175 Genome-wide genotyping array 30968 2009-01-16 19079262 Styrkarsdottir U 2008-12-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19079262 New sequence variants associated with bone mineral density. Bone mineral density (spine) 6,865 European ancestry individuals 8,510 European ancestry individuals Illumina [305051] 7 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST000295 Genome-wide genotyping array 6865 2009-01-16 19079262 Styrkarsdottir U 2008-12-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19079262 New sequence variants associated with bone mineral density. Bone mineral density (hip) 6,865 European ancestry individuals 8,510 European ancestry individuals Illumina [305051] 8 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST000297 Genome-wide genotyping array 6865 2009-06-01 19448189 Perlis RH 2009-05-15 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/19448189 A genomewide association study of response to lithium for prevention of recurrence in bipolar disorder. Response to lithium treatment in bipolar disorder 458 lithium-treated cases, 719 non-lithium treated cases 359 European ancestry lithium-treated cases Affymetrix [~ 1400000] (imputed) 0 response to lithium ion http://purl.obolibrary.org/obo/GO_0010226 GCST000402 Genome-wide genotyping array 1177 2012-08-20 22747683 Eriksson N 2012-06-30 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/22747683 Genetic variants associated with breast size also influence breast cancer risk. Breast size 16,175 European ancestry female individuals NA Illumina [7422970] (imputed) 38 breast size http://www.ebi.ac.uk/efo/EFO_0004884 GCST001585 Genome-wide genotyping array 16175 2012-07-11 22561518 Jin Y 2012-05-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22561518 Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo. Vitiligo 418 European ancestry cases, 2,810 European ancestry controls 1,377 European ancestry cases, 1,284 European ancestry controls Illumina [495821] 14 Vitiligo http://www.ebi.ac.uk/efo/EFO_0004208 GCST001509 Genome-wide genotyping array 3228 2013-11-09 23666240 Ruark E 2013-05-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23666240 Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14. Testicular germ cell tumor 986 European ancestry cases, 4,946 European ancestry controls 1,064 European ancestry cases, 10,082 European ancestry controls Illumina [307291] 15 testicular carcinoma http://www.ebi.ac.uk/efo/EFO_0005088 GCST002022 Genome-wide genotyping array 5932 2013-07-31 23455636 Fritsche LG 2013-03-03 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23455636 Seven new loci associated with age-related macular degeneration. Age-related macular degeneration 6,713 European ancestry cases, 48,402 European ancestry contols, 110 Southern Indian ancestry cases, 119 Southern Indian ancestry controls, 827 Japanese ancestry cases, 3,323 Japanese ancestry controls 9,070 European ancestry cases, 7,683 European ancestry contols, 461 East Asian ancestry cases, 547 East Asian ancestry controls Affymetrix, Illumina [2442884] (imputed) 19 age-related macular degeneration http://www.ebi.ac.uk/efo/EFO_0001365 GCST001884 Genome-wide genotyping array 59494 2013-08-02 23544013 Couch FJ 2013-03-27 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/23544013 Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. Ovarian cancer in BRCA1 mutation carriers 683 European ancestry cases, 2,044 European ancestry controls 1,706 European ancestry cases, 10,258 European ancestry controls Illumina [2568349] (imputed) 7 ovarian carcinoma http://www.ebi.ac.uk/efo/EFO_0001075 GCST001917 Genome-wide genotyping array 2727 2013-08-02 23544013 Couch FJ 2013-03-27 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/23544013 Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. Breast Cancer in BRCA1 mutation carriers 1,426 European ancestry cases, 1,301 European ancestry controls 6,031 European ancestry cases, 5,933 European ancestry controls Illumina [2568349] (imputed) 6 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST001916 Genome-wide genotyping array 2727 2013-03-27 23300278 Saxena R 2013-01-08 Diabetes www.ncbi.nlm.nih.gov/pubmed/23300278 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India. Type 2 diabetes 842 Punjabi Sikh ancestry cases, 774 Punjabi Sikh ancestry controls up to 2,512 Punjabi Sikh ancestry cases and 3,201 Punjabi Sikh ancestry controls, up to 16,128 South Asian ancestry cases and 23,846 South Asian ancestry controls, up to 16,746 East Asian ancestry cases and 16,961 East Asian ancestry controls, up to 8,130 European ancestry cases and 38,987 European ancestry controls Illumina [1232008] (imputed) 17 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST001809 Genome-wide genotyping array 1616 2012-12-16 23001997 Hou S 2012-12-06 Arthritis Rheum www.ncbi.nlm.nih.gov/pubmed/23001997 Identification of a susceptibility locus in STAT4 for Behçet's disease in Han Chinese in a genome-wide association study. Behcet's disease 147 Han Chinese ancestry cases, 951 Han Chinese ancestry controls 554 Han Chinese ancestry cases, 1,159 Han Chinese ancestry controls Affymetrix [661736] 6 Behcet's syndrome http://www.ebi.ac.uk/efo/EFO_0003780 GCST001768 Genome-wide genotyping array 1098 2013-01-08 23041938 Lee YJ 2012-10-06 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/23041938 Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease. Behcet's disease 367 Korean ancestry cases, 800 Korean ancestry controls 363 Japanese ancestry cases, 272 Japanese ancestry controls Affymetrix [594591] 0 Behcet's syndrome http://www.ebi.ac.uk/efo/EFO_0003780 GCST001707 Genome-wide genotyping array 1167 2012-04-06 22432041 Johnson MP 2012-03-14 PLoS One www.ncbi.nlm.nih.gov/pubmed/22432041 Genome-wide association scan identifies a risk locus for preeclampsia on 2q14, near the inhibin, beta B gene. Preeclampsia 538 European ancestry cases, 540 European ancestry controls 1,894 European ancestry cases, 3,022 European ancestry controls Illumina [648175] 0 preeclampsia http://www.ebi.ac.uk/efo/EFO_0000668 GCST001443 Genome-wide genotyping array 1078 2012-04-18 22430674 Lambert JC 2012-03-20 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/22430674 Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease. Alzheimer's disease 2,025 European ancestry cases, 5,328 European ancestry controls 7,913 European ancestry cases, 10,417 European ancestry controls Illumina [287956] 1 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST001449 Genome-wide genotyping array 7353 2013-08-10 23548203 Zhang M 2013-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23548203 Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans. Sunburns 9,283 European ancestry individuals 4,236 European ancestry individuals Affymetrix, Illumina [7588169] (imputed) 4 sunburn http://www.ebi.ac.uk/efo/EFO_0003958 GCST001933 Genome-wide genotyping array 9283 2013-08-10 23548203 Zhang M 2013-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23548203 Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans. Eye color 3871 European ancestry individuals 2,496 European ancestry individuals Affymetrix, Illumina [2469762] (imputed) 8 eye color http://www.ebi.ac.uk/efo/EFO_0003949 GCST001929 Genome-wide genotyping array 3871 2013-08-10 23548203 Zhang M 2013-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23548203 Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans. Hair color 7,070 European ancestry individuals 4,155 European ancestry individuals Affymetrix, Illumina [7588169] (imputed) 6 hair color http://www.ebi.ac.uk/efo/EFO_0003924 GCST001932 Genome-wide genotyping array 7070 2013-08-10 23548203 Zhang M 2013-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23548203 Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans. Non-melanoma skin cancer 6,747 European ancestry individuals 2,078 European ancestry individuals Affymetrix, Illumina [7588169] (imputed) 4 skin pigmentation http://www.ebi.ac.uk/efo/EFO_0003784 GCST001940 Genome-wide genotyping array 6747 2013-08-10 23548203 Zhang M 2013-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23548203 Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans. Tanning 9,678 European ancestry individuals NA Affymetrix, Illumina [7588169] (imputed) 5 suntan http://www.ebi.ac.uk/efo/EFO_0004279 GCST001939 Genome-wide genotyping array 9678 2012-12-06 23007406 Yang JJ 2012-09-24 Blood www.ncbi.nlm.nih.gov/pubmed/23007406 Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia. Acute lymphoblastic leukemia (childhood) 1,268 European, South Asian, East Asian, African American/Afro-Caribbean, Hispanic and other ancestry cases 1,267 European, South Asian, East Asian, African American/Afro-Caribbean, Hispanic and other ancestry cases Affymetrix [444044] 10 acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000220 GCST001693 Genome-wide genotyping array 1268 2011-07-13 21700265 Kullo IJ 2011-06-22 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/21700265 Complement receptor 1 gene variants are associated with erythrocyte sedimentation rate. Erythrocyte sedimentation rate 1,979 European ancestry individuals 5,628 European ancestry individuals Illumina [476395] 5 blood sedimentation http://www.ebi.ac.uk/efo/EFO_0004304 GCST001120 Genome-wide genotyping array 1979 2013-06-14 23459443 Avery CL 2013-03-05 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/23459443 Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval. QT interval (drug interaction) 33,781 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 17 QT interval http://www.ebi.ac.uk/efo/EFO_0004682 GCST001890 Genome-wide genotyping array 33781 2012-12-21 23042114 Hirota T 2012-10-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23042114 Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population. Atopic dermatitis 1,472 Japanese ancestry cases, 7,971 Japanese ancestry controls 1,856 Japanese ancestry cases, 7,021 Japanese ancestry controls Illumina [606164] 17 atopic eczema http://www.ebi.ac.uk/efo/EFO_0000274 GCST001709 Genome-wide genotyping array 9443 2013-02-23 23255317 Wooten EC 2012-12-19 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/23255317 Formin homology 2 domain containing 3 variants associated with hypertrophic cardiomyopathy. Hypertrophic cardiomyopathy 174 European ancestry cases, 823 European ancestry controls 1,012 European ancestry cases, 1,326 European ancestry controls Illumina [311399] 0 hypertrophic cardiomyopathy http://www.ebi.ac.uk/efo/EFO_0000538 GCST001778 Genome-wide genotyping array 997 2013-01-09 23041239 Traylor M 2012-10-05 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/23041239 Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies. Stroke (ischemic) 12,389 European ancestry cases, 62,004 European ancestry controls 1,322 Pakistani ancestry cases, 1,143 Pakistani ancestry controls, 12,025 European ancestry cases, 27,940 European ancestry controls Affymetrix, Illumina [NR] (imputed) 8 stroke http://www.ebi.ac.uk/efo/EFO_0000712 GCST001706 Genome-wide genotyping array 74393 2010-09-10 20663923 Anney R 2010-07-27 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/20663923 A genome-wide scan for common alleles affecting risk for autism. Autism 1,230 European ancestry child cases from 1,217 families, 155 African American Asian or Latino child cases from 152 families, 1,880 controls 783 European ancestry child cases from 440 families, 303 child cases from 155 families, 1,965 European, African American and other ancestry controls Illumina [842348] 2 autism http://www.ebi.ac.uk/efo/EFO_0003758 GCST000740 Genome-wide genotyping array 4634 2011-11-18 22001757 Chambers JC 2011-10-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22001757 Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Liver enzyme levels (alanine transaminase) Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals NA Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) 4 serum alanine aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004735 GCST001275 Genome-wide genotyping array 61089 2011-11-18 22001757 Chambers JC 2011-10-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22001757 Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Liver enzyme levels (alkaline phosphatase) Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals NA Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) 14 alkaline phosphatase measurement http://www.ebi.ac.uk/efo/EFO_0004533 GCST001276 Genome-wide genotyping array 61089 2011-11-18 22001757 Chambers JC 2011-10-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22001757 Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Liver enzyme levels (gamma-glutamyl transferase) Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals NA Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) 26 serum gamma-glutamyl transferase measurement http://www.ebi.ac.uk/efo/EFO_0004532 GCST001277 Genome-wide genotyping array 61089 2011-08-17 21747397 Rietschel M 2011-07-12 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/21747397 Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe. Schizophrenia 1,169 European ancestry cases, 3,714 European ancestry controls 7,303 European ancestry cases, 26,274 European ancestry controls Illumina [475427] 0 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST001152 Genome-wide genotyping array 4883 2012-05-10 22479202 Dastani Z 2012-03-29 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22479202 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. Adiponectin levels 29,347 European ancestry individuals, 4,232 African American individuals, 1,776 Filipino ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 10 adiponectin measurement http://www.ebi.ac.uk/efo/EFO_0004502 GCST001463 Genome-wide genotyping array 35355 2012-05-10 22479202 Dastani Z 2012-03-29 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22479202 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. Adiponectin levels 29,347 European ancestry individuals 10,536 European ancestry individuals Affymetrix, Illumina [NR] (imputed) 21 adiponectin measurement http://www.ebi.ac.uk/efo/EFO_0004502 GCST001465 Genome-wide genotyping array 29347 2013-06-11 23459936 Divaris K 2013-03-04 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23459936 Exploring the genetic basis of chronic periodontitis: a genome-wide association study. Periodontitis 4,504 European ancestry individuals 656 European ancestry and African American individuals Affymetrix [2135236] (imputed) 3 periodontitis http://www.ebi.ac.uk/efo/EFO_0000649 GCST001888 Genome-wide genotyping array 4504 2012-04-17 22426144 Long J 2012-03-16 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/22426144 Genome-wide association study identifies a possible susceptibility locus for endometrial cancer. Endometrial cancer 832 Chinese ancestry cases, 2,682 Chinese ancestry controls 6,864 European ancestry cases, 12,936 European ancestry controls, 796 Chinese ancestry cases, 978 Chinese ancestry controls Affymetrix [585963] 0 endometrial neoplasm http://www.ebi.ac.uk/efo/EFO_0004230 GCST001447 Genome-wide genotyping array 3514 2013-03-15 23263486 Kottgen A 2012-12-23 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23263486 Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Urate levels 49,825 European ancestry males, 60,522 European ancestry females Up to 32,813 European ancestry individuals Affymetrix, Illumina, Perlegen [2450547] (imputed) 47 urate measurement http://www.ebi.ac.uk/efo/EFO_0004531 GCST001791 Genome-wide genotyping array 110347 2013-03-15 23263486 Kottgen A 2012-12-23 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23263486 Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Gout 2,115 European ancestry cases, 67,259 European ancestry controls 1,036 European ancestry cases Affymetrix, Illumina [2538056] (imputed) 6 gout http://www.ebi.ac.uk/efo/EFO_0004274 GCST001790 Genome-wide genotyping array 69374 2012-11-28 23028356 Myouzen K 2012-09-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/23028356 Functional variants in NFKBIE and RTKN2 involved in activation of the NF-κB pathway are associated with rheumatoid arthritis in Japanese. Rheumatoid arthritis 2,303 Japanese ancestry cases, 3,380 Japanese ancestry controls 5,604 Japanese ancestry cases, 31,982 Japanese ancestry controls Illumina [NR] 2 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST001681 Genome-wide genotyping array 5683 2011-11-12 22004975 Li R 2011-10-17 Lupus www.ncbi.nlm.nih.gov/pubmed/22004975 Association of CD247 with systemic lupus erythematosus in Asian populations. Systemic lupus erythematosus 612 Chinese ancestry cases, 2,193 Chinese ancestry controls 2,866 East Asian ancestry cases, up to 4,808 East Asian ancestry controls, 473 Thai ancestry cases, up to 970 Thai ancestry controls Illumina [NR] 0 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST001279 Genome-wide genotyping array 2805 2011-08-03 21725308 Hu Z 2011-07-03 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21725308 A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese. Lung cancer 2,331 Han Chinese ancestry cases, 3,077 Han Chinese ancestry controls 6,313 Han Chinese ancestry cases, 6,409 Han Chinese ancestry controls Affymetrix [906703] 4 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST001140 Genome-wide genotyping array 5408 2013-01-11 23118916 Yang M 2012-10-31 PLoS One www.ncbi.nlm.nih.gov/pubmed/23118916 Genome-wide scan identifies variant in TNFSF13 associated with serum IgM in a healthy Chinese male population. IgM levels 1,999 Han Chinese ancestry individuals 1,496 East Asian ancestry individuals Illumina [1940243] (imputed) 3 serum IgM measurement http://www.ebi.ac.uk/efo/EFO_0004993 GCST001724 Genome-wide genotyping array 1999 2012-12-07 23028483 Ramasamy A 2012-09-28 PLoS One www.ncbi.nlm.nih.gov/pubmed/23028483 Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA. Asthma 1,716 European ancestry cases, 16,888 European ancestry controls 4,035 European ancestry cases, 11,251 European ancestry controls Affymetrix, Illumina [~ 2200000] (imputed) 2 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST001701 Genome-wide genotyping array 18604 2012-03-23 22293537 Kiyotani K 2012-01-29 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/22293537 A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy. Response to gemcitabine in pancreatic cancer 21 Japanese ancestry adverse reaction cases, 58 Japanese ancestry non-adverse reaction individuals 33 Japanese ancestry adverse reaction cases, 62 Japanese ancestry non-adverse reaction individuals Illumina [470064] 2 response to gemcitabine http://purl.obolibrary.org/obo/GO_0036272 GCST001390 Genome-wide genotyping array 79 2012-09-20 22823124 Verweij KJ 2012-07-24 Addict Biol www.ncbi.nlm.nih.gov/pubmed/22823124 The genetic aetiology of cannabis use initiation: a meta-analysis of genome-wide association studies and a SNP-based heritability estimation. Cannabis use (initiation) 10,091 individuals from 4,622 families NA Illumina [~ 2400000] (imputed) 6 drug dependence http://www.ebi.ac.uk/efo/EFO_0003890 GCST001616 Genome-wide genotyping array 14713 2013-05-26 23454411 Lin MT 2013-02-27 Transl Res www.ncbi.nlm.nih.gov/pubmed/23454411 A genome-wide association analysis identifies novel susceptibility loci for coronary arterial lesions in patients with Kawasaki disease. Coronary arterial lesions in patients with Kawasaki disease 64 East Asian ancestry serious cases, 70 East Asian ancestry minor cases 117 East Asian ancestry serious cases, 128 East Asian ancestry minor cases Affymetrix [470949] 0 coronary aneurysm http://www.ebi.ac.uk/efo/EFO_1000881 GCST001878 Genome-wide genotyping array 134 2012-09-12 22792071 Zheng HF 2012-07-05 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22792071 WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. Bone mineral density 5,672 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 1 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST001595 Genome-wide genotyping array 5672 2012-09-12 22792071 Zheng HF 2012-07-05 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22792071 WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. Cortical thickness 5,878 European ancestry individuals 1,032 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 2 cortical thickness http://www.ebi.ac.uk/efo/EFO_0004840 GCST001593 Genome-wide genotyping array 5878 2013-09-27 23551011 Zhao L 2013-04-02 Ann Hum Genet www.ncbi.nlm.nih.gov/pubmed/23551011 Genome-wide association study of pre-eclampsia detects novel maternal single nucleotide polymorphisms and copy-number variants in subsets of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study cohort. Preeclampsia 21 Afro-Caribbean cases, 1,010 Afro-Caribbean controls, 50 European ancestry cases, 1,202 European ancestry controls, 62 Hispanic cases, 658 Hispanic controls NA Illumina [2485249] (imputed) 18 preeclampsia http://www.ebi.ac.uk/efo/EFO_0000668 GCST001949 Genome-wide genotyping array 3003 2013-09-12 23535733 Garcia-Closas M 2013-04-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23535733 Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Breast cancer 4,193 European ancestry cases, 35,194 European ancestry controls 6,514 European ancestry cases, 41,455 European ancestry controls Illumina [NR] 17 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST001930 Genome-wide genotyping array 39387 2015-05-19 21685187 Siedlinski M 2011-06-16 Thorax www.ncbi.nlm.nih.gov/pubmed/21685187 Genome-wide association study of smoking behaviours in patients with COPD. Age at smoking initiation in chronic obstructive pulmonary disease 3,397 European ancestry cases NA Illumina [~ 6300000] (imputed) 21 smoking initiation http://www.ebi.ac.uk/efo/EFO_0005670 GCST001113 Genome-wide genotyping array 3397 2015-05-19 21685187 Siedlinski M 2011-06-16 Thorax www.ncbi.nlm.nih.gov/pubmed/21685187 Genome-wide association study of smoking behaviours in patients with COPD. Smoking cessation in chronic obstructive pulmonary disease 1,907 European ancestry former smoker cases, 1,164 European ancestry current smoker cases NA Illumina [~ 6300000] (imputed) 8 smoking cessation http://www.ebi.ac.uk/efo/EFO_0004319 GCST001108 Genome-wide genotyping array 3071 2015-05-18 21685187 Siedlinski M 2011-06-16 Thorax www.ncbi.nlm.nih.gov/pubmed/21685187 Genome-wide association study of smoking behaviours in patients with COPD. Current cigarettes per day in chronic obstructive pulmonary disease 1,113 European ancestry cases NA Illumina [~ 6300000] (imputed) 7 smoking behaviour measurement http://www.ebi.ac.uk/efo/EFO_0005671 GCST001111 Genome-wide genotyping array 1113 2015-05-18 21685187 Siedlinski M 2011-06-16 Thorax www.ncbi.nlm.nih.gov/pubmed/21685187 Genome-wide association study of smoking behaviours in patients with COPD. Lifetime average cigarettes per day in chronic obstructive pulmonary disease 3,440 European ancestry cases NA Illumina [~ 6300000] (imputed) 11 smoking behaviour measurement http://www.ebi.ac.uk/efo/EFO_0005671 GCST001112 Genome-wide genotyping array 3440 2010-12-03 20966902 Croteau-Chonka DC 2010-10-21 Obesity (Silver Spring) www.ncbi.nlm.nih.gov/pubmed/20966902 Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women. Weight 1,780 Filipino ancestry females NA Affymetrix [2073674] (imputed) 7 body weight http://www.ebi.ac.uk/efo/EFO_0004338 GCST000837 Genome-wide genotyping array 1780 2010-12-03 20966902 Croteau-Chonka DC 2010-10-21 Obesity (Silver Spring) www.ncbi.nlm.nih.gov/pubmed/20966902 Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women. Waist circumference 1,779 Filipino ancestry females NA Affymetrix [2073674] (imputed) 8 waist circumference http://www.ebi.ac.uk/efo/EFO_0004342 GCST000838 Genome-wide genotyping array 1779 2010-12-03 20966902 Croteau-Chonka DC 2010-10-21 Obesity (Silver Spring) www.ncbi.nlm.nih.gov/pubmed/20966902 Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women. Body mass index 1,780 Filipino ancestry females NA Affymetrix [2073674] (imputed) 6 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST000840 Genome-wide genotyping array 1780 2010-12-03 20966902 Croteau-Chonka DC 2010-10-21 Obesity (Silver Spring) www.ncbi.nlm.nih.gov/pubmed/20966902 Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women. Height 1,792 Filipino ancestry females NA Affymetrix [2073674] (imputed) 7 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST000839 Genome-wide genotyping array 1792 2010-12-09 21118971 Wu C 2010-11-30 Cancer Res www.ncbi.nlm.nih.gov/pubmed/21118971 Genome-wide interrogation identifies YAP1 variants associated with survival of small-cell lung cancer patients. Small-cell lung cancer (survival) 245 Han Chinese ancestry cases 305 Han Chinese ancestry cases Affymetrix [265996] 1 small cell lung carcinoma http://www.ebi.ac.uk/efo/EFO_0000702 GCST000896 Genome-wide genotyping array 245 2011-01-10 21105107 Clifford RJ 2010-12-01 Hepatology www.ncbi.nlm.nih.gov/pubmed/21105107 Genetic variations at loci involved in the immune response are risk factors for hepatocellular carcinoma. Hepatocellular carcinoma 180 Korean ancestry cases, 271 Korean ancestry controls 206 Korean ancestry cases, 416 East Asian ancestry controls, Affymetrix [658897] 3 hepatocellular carcinoma http://www.ebi.ac.uk/efo/EFO_0000182 GCST000902 Genome-wide genotyping array 451 2011-01-11 21124317 Wang K 2010-12-01 Nature www.ncbi.nlm.nih.gov/pubmed/21124317 Integrative genomics identifies LMO1 as a neuroblastoma oncogene. Neuroblastoma 1,627 European ancestry child cases, 3,254 European ancestry child controls 624 European ancestry child cases, 2,843 European ancestry child controls Illumina [480279] 3 neuroblastoma http://www.ebi.ac.uk/efo/EFO_0000621 GCST000901 Genome-wide genotyping array 4881 2011-01-12 21106707 Gu J 2010-11-24 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21106707 A genetic variant near the PMAIP1/Noxa gene is associated with increased bleomycin sensitivity. Response to bleomycin (chromatid breaks) 673 European ancestry individuals 834 European ancestry individuals Illumina [539437] 3 response to bleomycin, chromatid break measurement, response to antibiotic http://www.ebi.ac.uk/efo/EFO_0007592, http://www.ebi.ac.uk/efo/EFO_0007593, http://purl.obolibrary.org/obo/GO_0046677 GCST000882 Genome-wide genotyping array 673 2011-01-15 21131975 Purdue MP 2010-12-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21131975 Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3. Renal cell carcinoma 3,772 European ancestry cases, 8,505 European ancestry controls 2,198 European ancestry cases, 4,918 European ancestry controls Illumina [586069] 4 renal cell carcinoma http://www.ebi.ac.uk/efo/EFO_0000681 GCST000907 Genome-wide genotyping array 12277 2011-06-01 21572414 Suhre K 2011-05-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21572414 A genome-wide association study of metabolic traits in human urine. Urinary metabolites 862 European ancestry male individuals 1,862 European ancestry individuals Affymetrix [645249] 5 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST001073 Genome-wide genotyping array 862 2011-08-18 21799836 Cui B 2011-07-22 PLoS One www.ncbi.nlm.nih.gov/pubmed/21799836 A genome-wide association study confirms previously reported loci for type 2 diabetes in Han Chinese. Type 2 diabetes 793 Han Chinese ancestry cases, 806 Han Chinese ancestry controls 4,445 Han Chinese ancestry cases, 4,458 Han Chinese ancestry controls Illumina [474515] 2 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST001173 Genome-wide genotyping array 1599 2012-04-27 22446963 Okada Y 2012-03-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22446963 Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population. Rheumatoid arthritis 4,074 Japanese ancestry cases, 16,891 Japanese ancestry controls 5,277 Japanese ancestry cases, 21,684 Japanese ancestry controls Affymetrix, Illumina [1948139] 15 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST001454 Genome-wide genotyping array 20965 2011-01-14 21087763 Carrasquillo MM 2010-12-10 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/21087763 Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma. Progranulin levels 518 European ancestry controls 459 European ancestry controls Illumina [313504] 1 progranulin measurement http://www.ebi.ac.uk/efo/EFO_0004625 GCST000911 Genome-wide genotyping array 518 2013-08-28 23599027 Demerath EW 2013-04-17 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23599027 Genome-wide association study of age at menarche in African-American women. Menarche (age at onset) 18,089 African American individuals 2,850 African American individuals, 87,802 European ancestry inidividuals Affymetrix, Illumina [NR] (imputed) 15 age at menarche http://www.ebi.ac.uk/efo/EFO_0004703 GCST001973 Genome-wide genotyping array 18089 2013-07-05 23535911 Kitamoto T 2013-03-28 Hum Genet www.ncbi.nlm.nih.gov/pubmed/23535911 Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan. Pediatric non-alcoholic fatty liver disease activity score 392 Japanese ancestry cases, 934 Japanese ancestry controls 172 Japanese ancestry cases, 1,012 Japanese ancestry controls Illumina [261540] 4 non-alcoholic fatty liver disease, cirrhosis of liver http://www.ebi.ac.uk/efo/EFO_0003095, http://www.ebi.ac.uk/efo/EFO_0001422 GCST001928 Genome-wide genotyping array 1326 2013-09-18 23593239 van der Loos MJ 2013-04-04 PLoS One www.ncbi.nlm.nih.gov/pubmed/23593239 The molecular genetic architecture of self-employment. Self-employment 7,734 European ancestry cases, 42,893 European ancestry controls 737 cases, 2,534 controls Affymetrix, Illumina [~ 2400000] (imputed) 2 employment status http://www.ebi.ac.uk/efo/EFO_0005241 GCST001952 Genome-wide genotyping array 50627 2013-05-09 23371916 Dai X 2013-01-31 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/23371916 A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population. Bilirubin levels 1,452 Han Chinese ancestry individuals 8,830 Han Chinese ancestry individuals Affymetrix [658288] (imputed) 10 bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004570 GCST001846 Genome-wide genotyping array 1452 2012-04-25 22443383 Oudot-Mellakh T 2012-01-16 Br J Haematol www.ncbi.nlm.nih.gov/pubmed/22443383 Genome wide association study for plasma levels of natural anticoagulant inhibitors and protein C anticoagulant pathway: the MARTHA project. Hemostatic factors and hematological phenotypes 951 European ancestry individuals NA Illumina [472123] 9 hematological measurement http://www.ebi.ac.uk/efo/EFO_0004503 GCST001378 Genome-wide genotyping array 951 2012-04-18 22437316 Sarig O 2012-03-22 J Invest Dermatol www.ncbi.nlm.nih.gov/pubmed/22437316 Population-specific association between a polymorphic variant in ST18, encoding a pro-apoptotic molecule, and pemphigus vulgaris. Pemphigus vulgaris 100 Jewish cases, 397 Jewish controls 59 Jewish cases, 285 Jewish controls, 124 European ancestry cases, 275 European anestry controls, 126 North African ancestry controls, 246 North African ancestry controls Illumina [293635] 0 pemphigus vulgaris http://www.ebi.ac.uk/efo/EFO_0004719 GCST001452 Genome-wide genotyping array 497 2011-06-14 21625490 Andiappan AK 2011-05-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/21625490 Genome-wide association study for atopy and allergic rhinitis in a Singapore Chinese population. Atopy 515 Chinese ancestry cases, 486 Chinese ancestry controls 2,323 Chinese ancestry cases, 511 Chinese ancestry controls Illumina [460183] 0 atopy http://www.ebi.ac.uk/efo/EFO_0002686 GCST001075 Genome-wide genotyping array 1001 2012-11-05 22960237 Han Y 2012-08-31 Bone www.ncbi.nlm.nih.gov/pubmed/22960237 Bivariate genome-wide association study suggests fatty acid desaturase genes and cadherin DCHS2 for variation of both compressive strength index and appendicular lean mass in males. Comprehensive strength and appendicular lean mass 825 Chinese ancestry female individuals, 802 Chinese ancestry male individuals 1,059 European ancestry male individuals, 2,227 European ancestry female individuals Affymetrix [701525] 2 comprehensive strength index, muscle measurement http://www.ebi.ac.uk/efo/EFO_0004979, http://www.ebi.ac.uk/efo/EFO_0004515 GCST001656 Genome-wide genotyping array 1627 2013-04-17 23307926 Perry JR 2013-01-09 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23307926 A genome-wide association study of early menopause and the combined impact of identified variants. Menopause (age at onset) 3,493 European ancestry cases, 13,598 European ancestry controls 3,412 European ancestry cases, 4,928 European ancestry controls NR [NR] 8 age at menopause http://www.ebi.ac.uk/efo/EFO_0004704 GCST001810 Genome-wide genotyping array 17091 2011-12-03 22054870 De Jager PL 2011-11-03 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/22054870 A genome-wide scan for common variants affecting the rate of age-related cognitive decline. Cognitive decline 749 European ancestry individuals 1,562 European ancestry individuals, 717 cases Affymetrix [672266] 1 psychomotor performance http://www.ebi.ac.uk/efo/EFO_0004362 GCST001311 Genome-wide genotyping array 749 2011-12-15 22080838 Cho MH 2011-11-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22080838 A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. Chronic obstructive pulmonary disease 3,499 European ancestry cases, 1,922 European ancestry controls 983 cases, 1,876 sibling controls Illumina [797983] 4 chronic obstructive pulmonary disease http://www.ebi.ac.uk/efo/EFO_0000341 GCST001321 Genome-wide genotyping array 5421 2013-06-01 23456168 Hao Y 2013-03-03 Hum Genet www.ncbi.nlm.nih.gov/pubmed/23456168 Genome-wide association study in Han Chinese identifies three novel loci for human height. Height 6,534 Han Chinese ancestry individuals 1,881 Han Chinese ancestry individuals from 637 families Affymetrix [1532051] (imputed) 11 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST001885 Genome-wide genotyping array 6534 2013-07-01 23482656 Chen D 2013-03-12 J Natl Cancer Inst www.ncbi.nlm.nih.gov/pubmed/23482656 Genome-wide association study of susceptibility loci for cervical cancer. Cervical cancer 1,034 European ancestry cases, 3,948 European ancestry controls 1,140 European ancestry cases, 1,058 European ancestry controls Illumina [632668] 6 cervical carcinoma http://www.ebi.ac.uk/efo/EFO_0001061 GCST001900 Genome-wide genotyping array 4982 2014-03-01 23918034 Kuhnisch J 2013-08-07 Clin Oral Investig www.ncbi.nlm.nih.gov/pubmed/23918034 Genome-wide association study (GWAS) for molar-incisor hypomineralization (MIH). Molar-incisor hypomineralization 88 European ancestry cases, 580 European ancestry controls NA Affymetrix [2013491] (imputed) 5 molar-incisor hypomineralization http://www.ebi.ac.uk/efo/EFO_0005321 GCST002114 Genome-wide genotyping array 668 2013-06-06 23396134 Verhoeven VJ 2013-02-10 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23396134 Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Refractive error 37,382 European ancestry individuals, 3,995 Chinese ancestry individuals, 2,273 Malay ancestry individuals, 2,108 Indian ancestry individuals NA Affymetrix, Illumina [2500000] (imputed) 26 Abnormality of refraction http://purl.obolibrary.org/obo/HP_0000539 GCST001858 Genome-wide genotyping array 45758 2014-08-08 24047446 Schosser A 2013-09-19 World J Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/24047446 Genome-wide association study of co-occurring anxiety in major depression. Anxiety in major depressive disorder 1,080 European ancestry cases, 442 European ancestry controls NA Illumina [471581] 8 anxiety http://www.ebi.ac.uk/efo/EFO_0005230 GCST002202 Genome-wide genotyping array 1522 2014-08-08 24047446 Schosser A 2013-09-19 World J Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/24047446 Genome-wide association study of co-occurring anxiety in major depression. Anxiety and major depressive disorder 1,080 European ancestry cases, 1,588 European ancestry controls NA Illumina [471581] 3 unipolar depression, anxiety http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0005230 GCST002200 Genome-wide genotyping array 2668 2014-03-09 24024966 Teumer A 2013-08-14 J Clin Periodontol www.ncbi.nlm.nih.gov/pubmed/24024966 Genome-wide association study of chronic periodontitis in a general German population. Periodontitis (DPAL) up to 2,501 European ancestry individuals NA Affymetrix, Illumina [up to 17585496] (imputed) 15 periodontitis http://www.ebi.ac.uk/efo/EFO_0000649 GCST002129 Genome-wide genotyping array 2501 2014-03-09 24024966 Teumer A 2013-08-14 J Clin Periodontol www.ncbi.nlm.nih.gov/pubmed/24024966 Genome-wide association study of chronic periodontitis in a general German population. Periodontitis (PAL4Q3) up to 2,969 European ancestry individuals NA Affymetrix, Illumina [up to 17585496] (imputed) 18 periodontitis http://www.ebi.ac.uk/efo/EFO_0000649 GCST002136 Genome-wide genotyping array 2969 2014-03-09 24024966 Teumer A 2013-08-14 J Clin Periodontol www.ncbi.nlm.nih.gov/pubmed/24024966 Genome-wide association study of chronic periodontitis in a general German population. Periodontitis (Mean PAL) up to 4,032 European ancestry individuals NA Affymetrix, Illumina [up to 17585496] (imputed) 37 periodontitis http://www.ebi.ac.uk/efo/EFO_0000649 GCST002127 Genome-wide genotyping array 4032 2014-03-09 24024966 Teumer A 2013-08-14 J Clin Periodontol www.ncbi.nlm.nih.gov/pubmed/24024966 Genome-wide association study of chronic periodontitis in a general German population. Periodontitis (CDC/AAP) up to 3,915 European ancestry individuals NA Affymetrix, Illumina [up to 17585496] (imputed) 28 periodontitis http://www.ebi.ac.uk/efo/EFO_0000649 GCST002126 Genome-wide genotyping array 3915 2012-06-18 22494929 Rawal R 2012-04-16 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22494929 Meta-analysis of two genome-wide association studies identifies four genetic loci associated with thyroid function. Thyroid function 3,736 European ancestry individuals 3,727 European ancestry individuals Affymetrix, Illumina [2524918] (imputed) 4 thyroid function http://www.ebi.ac.uk/efo/EFO_0004296 GCST001487 Genome-wide genotyping array 3736 2011-12-17 22085899 Chen G 2011-11-16 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/22085899 UGT1A1 is a major locus influencing bilirubin levels in African Americans. Bilirubin levels 619 African American individuals NA Affymetrix [808465] 9 bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004570 GCST001324 Genome-wide genotyping array 619 2011-12-10 21983787 Barrett JH 2011-10-09 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21983787 Genome-wide association study identifies three new melanoma susceptibility loci. Melanoma 2,804 European ancestry cases, 7,618 European ancestry controls 5,551 European ancestry cases, 7,449 European ancestry controls Illumina [594997] 10 melanoma http://www.ebi.ac.uk/efo/EFO_0000756 GCST001267 Genome-wide genotyping array 10422 2008-10-14 18762592 van den Oord EJ 2008-09-01 Arch Gen Psychiatry www.ncbi.nlm.nih.gov/pubmed/18762592 Genomewide association analysis followed by a replication study implicates a novel candidate gene for neuroticism. Neuroticism 1,227 European ancestry individuals 1,880 European ancestry individuals Affymetrix [420287] 3 neurotic disorder http://www.ebi.ac.uk/efo/EFO_0004257 GCST000226 Genome-wide genotyping array 1227 2013-04-30 23480133 Kim Y 2011-02-28 World J Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/23480133 Association of intronic sequence variant in the gene encoding spleen tyrosine kinase with susceptibility to vascular dementia. Vascular dementia 84 Korean ancestry cases, 200 Korean ancestry controls 113 Korean ancestry cases, 255 Korean ancestry controls NR [300640] 1 vascular dementia http://www.ebi.ac.uk/efo/EFO_0004718 GCST000993 Genome-wide genotyping array 284 2013-06-06 23453885 Smoller JW 2013-02-27 Lancet www.ncbi.nlm.nih.gov/pubmed/23453885 Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) 6,990 European ancestry Bipolar disorder cases, 9,227 European ancestry Major depressive disorder cases, 9,379 European ancestry Schizophrenia cases, 161 European ancestry Autism spectrum disorder cases, 4,788 European ancestry Autism spectrum disorder trio cases, 840 European ancestry Attention deficit-hyperactivity disorder cases, 1,947 European ancestry Attention defcit-hyperactivity disorder trio cases, 27,888 European ancestry controls NA NR [1252901] (imputed) 74 attention deficit hyperactivity disorder, unipolar depression, schizophrenia, autism spectrum disorder, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0003756, http://www.ebi.ac.uk/efo/EFO_0000289 GCST001877 Genome-wide genotyping array 61220 2011-03-18 21298027 Festen EA 2011-01-27 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21298027 A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease. Crohn's disease and celiac disease 3,230 European ancestry Crohn's disease cases, 768 European ancestry celiac disease cases, 6,251 European ancestry controls 1,835 European ancestry Crohn's disease cases, 3,149 European ancestry celiac disease cases, 6,383 European ancestry controls Affymetrix, Illumina [471504] 2 celiac disease, Crohn's disease http://www.ebi.ac.uk/efo/EFO_0001060, http://www.ebi.ac.uk/efo/EFO_0000384 GCST000955 Genome-wide genotyping array 10249 2011-04-07 21372407 Takeuchi F 2011-03-01 Circ J www.ncbi.nlm.nih.gov/pubmed/21372407 Confirmation of ALDH2 as a Major locus of drinking behavior and of its variants regulating multiple metabolic phenotypes in a Japanese population. Drinking behavior 733 Japanese ancestry cases, 729 Japanese ancestry controls 2,794 Japanese ancestry drinkers, 1,521 Japanese ancestry chance drinkers, 1,351 Japanese ancestry non-drinkers Illumina [456827] 2 drinking behavior http://www.ebi.ac.uk/efo/EFO_0004315 GCST000994 Genome-wide genotyping array 1462 2012-07-21 22566498 Turner ST 2012-05-07 Hypertension www.ncbi.nlm.nih.gov/pubmed/22566498 Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker. Response to angiotensin II receptor blocker therapy 198 European ancestry hypertensive individuals, 193 African American hypertensive individuals NA Affymetrix [~ 2300000] (imputed) 20 response to candesartan http://purl.obolibrary.org/obo/GO_1901556 GCST001520 Genome-wide genotyping array 391 2012-07-21 22566498 Turner ST 2012-05-07 Hypertension www.ncbi.nlm.nih.gov/pubmed/22566498 Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker. Response to angiotensin II receptor blocker therapy (opposite direction w/ diuretic therapy) 394 European ancestry hypertensive individuals, 193 African American hypertensive individuals NA Affymetrix [~ 2300000] (imputed) 5 response to candesartan http://purl.obolibrary.org/obo/GO_1901556 GCST001518 Genome-wide genotyping array 587 2013-04-09 23251661 Comuzzie AG 2012-12-04 PLoS One www.ncbi.nlm.nih.gov/pubmed/23251661 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. Obesity-related traits 815 Hispanic children from 263 families NA Illumina [899892] 949 cortisol secretion measurement, hormone measurement, antioxidant measurement, CCL2 measurement, body mass index, IGFBP-3 measurement, fatty acid measurement, tumor necrosis factor-alpha measurement, gestational age, energy expenditure, sleep measurement, metabolic rate measurement, urinary metabolite measurement, blood urea nitrogen measurement, vitamin B12 measurement, energy intake, ICAM-1 measurement, body height, hip circumference, arm span, physical activity, heart rate, protein measurement, estradiol measurement, thyroid stimulating hormone measurement, waist circumference, total cholesterol measurement, interleukin-6 measurement, body composition measurement, birth weight, amino acid measurement, C-reactive protein measurement, HOMA-IR, head circumference, adiponectin measurement, high density lipoprotein cholesterol measurement, aspartate aminotransferase measurement, leptin measurement, transforming growth factor beta measurement, systolic blood pressure, IGFBP-1 measurement, bone density, body weight, fasting blood glucose measurement, homocysteine measurement, folic acid measurement, serum alanine aminotransferase measurement, CCL5 measurement, IGF-1 measurement, testosterone measurement, insulin sensitivity measurement, diastolic blood pressure, maximal oxygen uptake measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, lean body mass, fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004642, http://www.ebi.ac.uk/efo/EFO_0004730, http://www.ebi.ac.uk/efo/EFO_0005119, http://www.ebi.ac.uk/efo/EFO_0004749, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004626, http://www.ebi.ac.uk/efo/EFO_0005110, http://www.ebi.ac.uk/efo/EFO_0004684, http://www.ebi.ac.uk/efo/EFO_0005112, http://www.ebi.ac.uk/efo/EFO_0005109, http://www.ebi.ac.uk/efo/EFO_0004870, http://www.ebi.ac.uk/efo/EFO_0005115, http://www.ebi.ac.uk/efo/EFO_0005116, http://www.ebi.ac.uk/efo/EFO_0004741, http://www.ebi.ac.uk/efo/EFO_0004620, http://www.ebi.ac.uk/efo/EFO_0003939, http://www.ebi.ac.uk/efo/EFO_0004520, http://www.ebi.ac.uk/efo/EFO_0004339, http://www.ebi.ac.uk/efo/EFO_0005093, http://www.ebi.ac.uk/efo/EFO_0005108, http://www.ebi.ac.uk/efo/EFO_0003940, http://www.ebi.ac.uk/efo/EFO_0004326, http://www.ebi.ac.uk/efo/EFO_0004747, http://www.ebi.ac.uk/efo/EFO_0004697, http://www.ebi.ac.uk/efo/EFO_0004748, http://www.ebi.ac.uk/efo/EFO_0004342, http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0004810, http://www.ebi.ac.uk/efo/EFO_0005106, http://www.ebi.ac.uk/efo/EFO_0004344, http://www.ebi.ac.uk/efo/EFO_0005134, http://www.ebi.ac.uk/efo/EFO_0004458, http://www.ebi.ac.uk/efo/EFO_0004501, http://www.ebi.ac.uk/efo/EFO_0005114, http://www.ebi.ac.uk/efo/EFO_0004502, http://www.ebi.ac.uk/efo/EFO_0004612, http://www.ebi.ac.uk/efo/EFO_0004736, http://www.ebi.ac.uk/efo/EFO_0005000, http://www.ebi.ac.uk/efo/EFO_0004818, http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0005118, http://www.ebi.ac.uk/efo/EFO_0003923, http://www.ebi.ac.uk/efo/EFO_0004338, http://www.ebi.ac.uk/efo/EFO_0004465, http://www.ebi.ac.uk/efo/EFO_0004578, http://www.ebi.ac.uk/efo/EFO_0005111, http://www.ebi.ac.uk/efo/EFO_0004735, http://www.ebi.ac.uk/efo/EFO_0005117, http://www.ebi.ac.uk/efo/EFO_0004627, http://www.ebi.ac.uk/efo/EFO_0004908, http://www.ebi.ac.uk/efo/EFO_0004471, http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004887, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0004611, http://www.ebi.ac.uk/efo/EFO_0004995, http://www.ebi.ac.uk/efo/EFO_0004466 GCST001762 Genome-wide genotyping array 1078 2012-08-14 22566634 Benjamin DJ 2012-05-07 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/22566634 The genetic architecture of economic and political preferences. Economic and political preferences 9,617 European ancestry individuals NA Illumina [628922] 17 economic and social preference http://www.ebi.ac.uk/efo/EFO_0004827 GCST001519 Genome-wide genotyping array 9617 2012-08-14 22566634 Benjamin DJ 2012-05-07 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/22566634 The genetic architecture of economic and political preferences. Economic and political preferences (environmentalism) 9,617 European ancestry individuals NA Illumina [628922] 17 economic and social preference http://www.ebi.ac.uk/efo/EFO_0004827 GCST001512 Genome-wide genotyping array 9617 2012-08-14 22566634 Benjamin DJ 2012-05-07 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/22566634 The genetic architecture of economic and political preferences. Economic and political preferences (fairness) 9,617 European ancestry individuals NA Illumina [628922] 7 economic and social preference http://www.ebi.ac.uk/efo/EFO_0004827 GCST001513 Genome-wide genotyping array 9617 2012-08-14 22566634 Benjamin DJ 2012-05-07 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/22566634 The genetic architecture of economic and political preferences. Economic and political preferences (feminism/equality) 9,617 European ancestry individuals NA Illumina [628922] 12 economic and social preference http://www.ebi.ac.uk/efo/EFO_0004827 GCST001514 Genome-wide genotyping array 9617 2012-08-14 22566634 Benjamin DJ 2012-05-07 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/22566634 The genetic architecture of economic and political preferences. Economic and political preferences (immigration/crime) 9,617 European ancestry individuals NA Illumina [628922] 15 economic and social preference http://www.ebi.ac.uk/efo/EFO_0004827 GCST001515 Genome-wide genotyping array 9617 2012-08-14 22566634 Benjamin DJ 2012-05-07 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/22566634 The genetic architecture of economic and political preferences. Economic and political preferences (time) 9,617 European ancestry individuals NA Illumina [628922] 10 economic and social preference http://www.ebi.ac.uk/efo/EFO_0004827 GCST001511 Genome-wide genotyping array 9617 2012-07-09 22561531 Wan YI 2012-05-05 Thorax www.ncbi.nlm.nih.gov/pubmed/22561531 Genome-wide association study to identify genetic determinants of severe asthma. Asthma 933 European ancestry cases, 3,346 European ancestry controls 231 European ancestry cases, 1,345 European ancestry controls Illumina [6103628] (imputed) 7 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST001508 Genome-wide genotyping array 4279 2012-06-20 22556244 Kenny EE 2012-05-04 Science www.ncbi.nlm.nih.gov/pubmed/22556244 Melanesian blond hair is caused by an amino acid change in TYRP1. Hair color 43 Solomon Islander ancestry blond haired individuals, 42 Solomon Islander ancestry dark haired individuals NA Illumina [589241] 1 hair color http://www.ebi.ac.uk/efo/EFO_0003924 GCST001507 Genome-wide genotyping array 85 2011-01-16 21196492 Okada Y 2010-12-31 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21196492 Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus. C-reactive protein 10,112 Japanese ancestry individuals 2,742 Japanese ancestry individuals Illumina [477784] 4 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST000933 Genome-wide genotyping array 10112 2012-05-25 22493691 Eriksson N 2012-04-06 PLoS One www.ncbi.nlm.nih.gov/pubmed/22493691 Novel associations for hypothyroidism include known autoimmune risk loci. Hypothyroidism 3,736 European ancestry cases, 35,546 European ancestry controls NA Illumina [870065] 19 hypothyroidism http://www.ebi.ac.uk/efo/EFO_0004705 GCST001474 Genome-wide genotyping array 39282 2012-10-09 22863734 Ludwig KU 2012-08-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22863734 Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. Orofacial clefts Up to 666 European ancestry trios, 399 European ancestry cases, 1,318 European ancestry controls up to 795 East Asian ancestry trios NR [497084] 31 cleft lip http://www.ebi.ac.uk/efo/EFO_0003959 GCST001628 Genome-wide genotyping array 2383 2013-09-18 23636237 Tanaka T 2013-05-01 Am J Clin Nutr www.ncbi.nlm.nih.gov/pubmed/23636237 Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. Dietary macronutrient intake 37,537 European ancestry individuals 33,533 European ancestry individuals Affymetrix, Illumina [2500000] (imputed) 6 energy intake http://www.ebi.ac.uk/efo/EFO_0003939 GCST001988 Genome-wide genotyping array 37537 2013-09-17 23636237 Tanaka T 2013-05-01 Am J Clin Nutr www.ncbi.nlm.nih.gov/pubmed/23636237 Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. Dietary macronutrient intake 37,537 European ancestry individuals 41,257 European ancestry individuals Affymetrix, Illumina [2500000] (imputed) 1 energy intake http://www.ebi.ac.uk/efo/EFO_0003939 GCST001989 Genome-wide genotyping array 37537 2011-08-05 21750109 Rafnar T 2011-07-12 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21750109 European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene. Bladder cancer 2,234 European ancestry cases, 41,603 European ancestry controls 3,371 European ancestry cases, 10,261 European ancestry controls, 269 Iranian ancestry cases, 246 Iranian ancestry controls Illumina [5340737] (imputed) 1 bladder carcinoma http://www.ebi.ac.uk/efo/EFO_0000292 GCST001153 Genome-wide genotyping array 43837 2011-05-27 21546767 Murea M 2011-05-05 Am J Nephrol www.ncbi.nlm.nih.gov/pubmed/21546767 Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes. Dialysis-related mortality 610 African American type 2 diabetes cases NA Affymetrix [832357] 26 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST001066 Genome-wide genotyping array 612 2012-08-07 22683712 Freilinger T 2012-06-10 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22683712 Genome-wide association analysis identifies susceptibility loci for migraine without aura. Migraine 2,326 European ancestry cases, 4,580 European ancestry controls 2,508 European ancestry cases, 2,652 European ancestry controls Illumina [1246388] (imputed) 10 migraine disorder http://www.ebi.ac.uk/efo/EFO_0003821 GCST001563 Genome-wide genotyping array 6906 2012-08-07 22610502 Kennedy RB 2012-05-19 Hum Genet www.ncbi.nlm.nih.gov/pubmed/22610502 Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients. Immune reponse to smallpox (secreted IL-12p40) Up to 512 European ancestry individuals, up to 199 African American individuals NA Illumina [NR] 10 response to vaccine, cytokine measurement http://www.ebi.ac.uk/efo/EFO_0004645, http://www.ebi.ac.uk/efo/EFO_0004873 GCST001537 Genome-wide genotyping array 711 2012-08-07 22610502 Kennedy RB 2012-05-19 Hum Genet www.ncbi.nlm.nih.gov/pubmed/22610502 Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients. Immune reponse to smallpox (secreted IL-2) Up to 512 European ancestry individuals, up to 199 African American individuals NA Illumina [NR] 17 response to vaccine, cytokine measurement http://www.ebi.ac.uk/efo/EFO_0004645, http://www.ebi.ac.uk/efo/EFO_0004873 GCST001535 Genome-wide genotyping array 711 2012-08-07 22610502 Kennedy RB 2012-05-19 Hum Genet www.ncbi.nlm.nih.gov/pubmed/22610502 Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients. Immune reponse to smallpox (secreted IL-10) Up to 512 European ancestry individuals, up to 199 African American individuals NA Illumina [NR] 6 response to vaccine, cytokine measurement http://www.ebi.ac.uk/efo/EFO_0004645, http://www.ebi.ac.uk/efo/EFO_0004873 GCST001534 Genome-wide genotyping array 711 2012-08-07 22610502 Kennedy RB 2012-05-19 Hum Genet www.ncbi.nlm.nih.gov/pubmed/22610502 Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients. Immune reponse to smallpox (secreted IL-1beta) Up to 512 European ancestry individuals, up to 199 African American individuals NA Illumina [NR] 13 response to vaccine, cytokine measurement http://www.ebi.ac.uk/efo/EFO_0004645, http://www.ebi.ac.uk/efo/EFO_0004873 GCST001533 Genome-wide genotyping array 711 2012-08-07 22610502 Kennedy RB 2012-05-19 Hum Genet www.ncbi.nlm.nih.gov/pubmed/22610502 Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients. Immune response to smallpox vaccine (IL-6) Up to 512 European ancestry individuals, 199 African American individuals NA Illumina [NR] 9 response to vaccine, cytokine measurement http://www.ebi.ac.uk/efo/EFO_0004645, http://www.ebi.ac.uk/efo/EFO_0004873 GCST001532 Genome-wide genotyping array 711 2012-08-07 22610502 Kennedy RB 2012-05-19 Hum Genet www.ncbi.nlm.nih.gov/pubmed/22610502 Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients. Immune reponse to smallpox (secreted TNF-alpha) Up to 512 European ancestry individuals, up to 199 African American individuals NA Illumina [NR] 6 response to vaccine, cytokine measurement http://www.ebi.ac.uk/efo/EFO_0004645, http://www.ebi.ac.uk/efo/EFO_0004873 GCST001536 Genome-wide genotyping array 711 2012-08-07 22610502 Kennedy RB 2012-05-19 Hum Genet www.ncbi.nlm.nih.gov/pubmed/22610502 Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients. Immune reponse to smallpox (secreted IFN-alpha) Up to 512 European ancestry individuals, up to 199 African American individuals NA Illumina [NR] 32 response to vaccine, cytokine measurement http://www.ebi.ac.uk/efo/EFO_0004645, http://www.ebi.ac.uk/efo/EFO_0004873 GCST001538 Genome-wide genotyping array 711 2013-08-21 21897333 Irvin MR 2011-12-01 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/21897333 Genes linked to energy metabolism and immunoregulatory mechanisms are associated with subcutaneous adipose tissue distribution in HIV-infected men. Fat distribution (HIV) 192 European ancestry male cases NA Illumina [319818] 17 body fat distribution http://www.ebi.ac.uk/efo/EFO_0004341 GCST001343 Genome-wide genotyping array 192 2013-11-29 23726366 Coram MA 2013-05-29 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/23726366 Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations. LDL cholesterol 7,861 African American individuals, 3,425 Hispanic individuals 7,138 African American individuals Affymetrix [NR] 5 lipid measurement http://www.ebi.ac.uk/efo/EFO_0004529 GCST002042 Genome-wide genotyping array 11286 2013-11-29 23726366 Coram MA 2013-05-29 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/23726366 Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations. Triglycerides 7,601 African American individuals, 3,335 Hispanic individuals 7,138 African American individuals Affymetrix [NR] 7 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST002044 Genome-wide genotyping array 10936 2013-12-03 23726366 Coram MA 2013-05-29 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/23726366 Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations. HDL cholesterol 7,917 African American individuals, 3,506 Hispanic individuals 7,138 African American individuals Affymetrix [NR] 9 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST002043 Genome-wide genotyping array 11423 2012-07-04 22542470 Ovsyannikova IG 2012-04-25 Vaccine www.ncbi.nlm.nih.gov/pubmed/22542470 Genome-wide association study of antibody response to smallpox vaccine. Immune response to smallpox vaccine (IL-6) 217 African American individuals, 580 European ancestry individuals, 217 Hispanic individuals NA Illumina [NR] 37 response to vaccine http://www.ebi.ac.uk/efo/EFO_0004645 GCST001491 Genome-wide genotyping array 1014 2014-04-04 24023260 Wu Y 2013-09-10 J Lipid Res www.ncbi.nlm.nih.gov/pubmed/24023260 Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels. Lipid traits 1,782 Filipino ancestry mothers 1,719 Filipino ancestry offsprings Affymetrix [~ 3700000] (imputed) 6 total cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0004611, http://www.ebi.ac.uk/efo/EFO_0004612 GCST002174 Genome-wide genotyping array 1782 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Calcium levels 71,701 Japanese ancestry individuals NA Illumina [6108953] (imputed) 17 calcium measurement http://www.ebi.ac.uk/efo/EFO_0004838 GCST005982 Genome-wide genotyping array 71701 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Phosphorus levels 42,793 Japanese ancestry individuals NA Illumina [6108953] (imputed) 10 phosphorus measurement http://www.ebi.ac.uk/efo/EFO_0004861 GCST005981 Genome-wide genotyping array 42793 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Total bilirubin levels 110,207 Japanese ancestry individuals NA Illumina [6108953] (imputed) 20 bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004570 GCST005980 Genome-wide genotyping array 110207 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Systolic blood pressure 136,597 Japanese ancestry individuals NA Illumina [6108953] (imputed) 23 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST005979 Genome-wide genotyping array 136597 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Diastolic blood pressure 136,615 Japanese ancestry individuals NA Illumina [6108953] (imputed) 18 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST005978 Genome-wide genotyping array 136615 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Mean arterial pressure 136,482 Japanese ancestry individuals NA Illumina [6108953] (imputed) 32 mean arterial pressure http://www.ebi.ac.uk/efo/EFO_0006340 GCST006010 Genome-wide genotyping array 136482 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Pulse pressure 136,249 Japanese ancestry individuals NA Illumina [6108953] (imputed) 17 pulse pressure measurement http://www.ebi.ac.uk/efo/EFO_0005763 GCST006009 Genome-wide genotyping array 136249 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Left ventricular internal dimension in diastole 19,676 Japanese ancestry individuals NA Illumina [6108953] (imputed) 3 left ventricular diastolic function measurement http://www.ebi.ac.uk/efo/EFO_0008204 GCST006008 Genome-wide genotyping array 19676 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Left ventricular internal dimension in systole 19,586 Japanese ancestry individuals NA Illumina [6108953] (imputed) 4 left ventricular systolic function measurement http://www.ebi.ac.uk/efo/EFO_0008206 GCST006007 Genome-wide genotyping array 19586 2018-07-30 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Relative wall thickness 19,311 Japanese ancestry individuals NA Illumina [6108953] (imputed) 1 heart relative wall thickness http://www.ebi.ac.uk/efo/EFO_0009286 GCST006033 Genome-wide genotyping array 19311 2018-07-30 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Fractional shortening 19,580 Japanese ancestry individuals NA Illumina [6108953] (imputed) 4 fractional shortening http://www.ebi.ac.uk/efo/EFO_0009285 GCST006029 Genome-wide genotyping array 19580 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Ejection fraction 19,516 Japanese ancestry individuals NA Illumina [6108953] (imputed) 3 ejection fraction measurement http://www.ebi.ac.uk/efo/EFO_0005527 GCST006006 Genome-wide genotyping array 19516 2018-07-30 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Interventricular septum thickness 19,318 Japanese ancestry individuals NA Illumina [6108953] (imputed) 0 interventricular septum thickness http://www.ebi.ac.uk/efo/EFO_0009287 GCST006028 Genome-wide genotyping array 19318 2018-07-30 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Posterior wall thickness 19,373 Japanese ancestry individuals NA Illumina [6108953] (imputed) 0 posterior wall thickness http://www.ebi.ac.uk/efo/EFO_0009288 GCST006027 Genome-wide genotyping array 19373 2018-07-30 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Left ventricular mass 19,076 Japanese ancestry individuals NA Illumina [6108953] (imputed) 0 left ventricular mass http://www.ebi.ac.uk/efo/EFO_0009289 GCST006026 Genome-wide genotyping array 19076 2018-07-30 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Left ventricular mass index 17,837 Japanese ancestry individuals NA Illumina [6108953] (imputed) 0 left ventricular mass index http://www.ebi.ac.uk/efo/EFO_0009290 GCST006025 Genome-wide genotyping array 17837 2018-07-30 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. E/A ratio 8,600 Japanese ancestry individuals NA Illumina [6108953] (imputed) 0 E/A ratio http://www.ebi.ac.uk/efo/EFO_0009291 GCST006024 Genome-wide genotyping array 8600 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. High density lipoprotein cholesterol levels 70,657 Japanese ancestry individuals NA Illumina [6108953] (imputed) 53 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST006005 Genome-wide genotyping array 70657 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Low density lipoprotein cholesterol levels 72,866 Japanese ancestry individuals NA Illumina [6108953] (imputed) 29 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST006004 Genome-wide genotyping array 72866 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Triglyceride levels 105,597 Japanese ancestry individuals NA Illumina [6108953] (imputed) 36 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST006003 Genome-wide genotyping array 105597 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Blood sugar levels 93,146 Japanese ancestry individuals NA Illumina [6108953] (imputed) 21 glucose measurement http://www.ebi.ac.uk/efo/EFO_0004468 GCST006002 Genome-wide genotyping array 93146 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Hemoglobin A1c levels 42,790 Japanese ancestry individuals NA Illumina [6108953] (imputed) 28 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST006001 Genome-wide genotyping array 42790 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Immunoglobulin measurement (zinc sulfate turbidity test) 12,303 Japanese ancestry individuals NA Illumina [6108953] (imputed) 4 serum IgG measurement http://www.ebi.ac.uk/efo/EFO_0004565 GCST006000 Genome-wide genotyping array 12303 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Aspartate aminotransferase levels 134,154 Japanese ancestry individuals NA Illumina [6108953] (imputed) 30 aspartate aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004736 GCST005999 Genome-wide genotyping array 134154 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Alanine transaminase levels 134,182 Japanese ancestry individuals NA Illumina [6108953] (imputed) 27 serum alanine aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004735 GCST005998 Genome-wide genotyping array 134182 2017-11-17 28957384 Kim SK 2017-09-28 PLoS One www.ncbi.nlm.nih.gov/pubmed/28957384 Two genetic loci associated with ankle injury. Ankle injury 1,421 European ancestry cases, 154 Hispanic/Latino cases, 121 East Asian ancestry cases, 81,843 European ancestry controls, 8,406 Hispanic/Latino controls, 7,397 East Asian ancestry controls NA Affymetrix [8183964] (imputed) 42 ankle injury http://www.ebi.ac.uk/efo/EFO_1002021 GCST004952 Genome-wide genotyping array 99342 2017-02-10 27564568 Liu C 2016-08-26 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/27564568 Genomewide Approach Validates Thiopurine Methyltransferase Activity Is a Monogenic Pharmacogenomic Trait. Thiopurine methyltransferase activity in acute lymphoblastic leukemia patients treated with mercaptopurines up to 407 European ancestry cases, up to 138 African ancestry cases, up to 251 Hispanic cases, up to 57 Asian ancestry cases, up to 110 other ancestry cases NA Affymetrix, Illumina [9000000] (imputed) 1 thiopurine methyltransferase activity measurement, response to mercaptopurine http://www.ebi.ac.uk/efo/EFO_0007852, http://www.ebi.ac.uk/efo/EFO_0007853 GCST003609 Genome-wide genotyping array 963 2017-02-19 27561104 Pirastu N 2016-08-25 Sci Rep www.ncbi.nlm.nih.gov/pubmed/27561104 Non-additive genome-wide association scan reveals a new gene associated with habitual coffee consumption. Coffee consumption 370 Carlantino (founder/genetic isolate) individuals, 843 Friuli Venezia Giulia (founder/genetic isolate) individuals 1,731 Erasmus Rucphen (founder/genetic isolate) individuals Illumina [at least 3692733] (imputed) 5 coffee consumption, cups of coffee per day measurement http://www.ebi.ac.uk/efo/EFO_0004330, http://www.ebi.ac.uk/efo/EFO_0006782 GCST003621 Genome-wide genotyping array 1213 2017-11-08 28983962 Cheung JPY 2017-10-06 J Orthop Res www.ncbi.nlm.nih.gov/pubmed/28983962 Etiology of developmental spinal stenosis: A genome-wide association study. Lumbar spinal stenosis 469 Chinese ancestry individuals NA Illumina [~ 800000] 0 spinal stenosis http://www.ebi.ac.uk/efo/EFO_0007490 GCST004945 Genome-wide genotyping array 469 2017-11-10 28991256 Li Z 2017-10-09 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28991256 Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia. Schizophrenia 7,699 Chinese ancestry cases, 35,476 European ancestry cases, 18,327 Chinese ancestry controls, 46,839 European ancestry controls 4,384 Chinese ancestry cases, 5,770 Chinese ancestry controls Affymetrix, Illumina [up to 5107227] (imputed) 222 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST004946 Genome-wide genotyping array 108341 2018-04-25 24076602 Beecham AH 2013-11-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24076602 Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Multiple sclerosis 14,498 European ancestry cases, 24,091 European ancestry controls 14,802 European ancestry cases, 26,703 European ancestry controls Illumina [161311] 126 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST005531 Targeted genotyping array [ImmunoChip] 38589 2017-02-23 27560520 Shaffer JR 2016-08-25 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/27560520 Genome-Wide Association Study Reveals Multiple Loci Influencing Normal Human Facial Morphology. Cranial base width 2,447 European ancestry individuals 671 European ancestry individuals Illumina [34985077] (imputed) 4 facial width measurement http://www.ebi.ac.uk/efo/EFO_0007855 GCST003641 Genome-wide genotyping array 2447 2017-02-23 27560520 Shaffer JR 2016-08-25 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/27560520 Genome-Wide Association Study Reveals Multiple Loci Influencing Normal Human Facial Morphology. Eye morphology 2,447 European ancestry individuals 671 European ancestry individuals Illumina [34985077] (imputed) 5 eye morphology measurement http://www.ebi.ac.uk/efo/EFO_0007858 GCST003642 Genome-wide genotyping array 2447 2017-02-23 27560520 Shaffer JR 2016-08-25 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/27560520 Genome-Wide Association Study Reveals Multiple Loci Influencing Normal Human Facial Morphology. Nose morphology 2,447 European ancestry individuals 671 European ancestry individuals Illumina [34985077] (imputed) 8 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST003643 Genome-wide genotyping array 2447 2017-02-23 27560520 Shaffer JR 2016-08-25 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/27560520 Genome-Wide Association Study Reveals Multiple Loci Influencing Normal Human Facial Morphology. Lip morphology 2,447 European ancestry individuals 671 European ancestry individuals Illumina [34985077] (imputed) 5 lip morphology measurement http://www.ebi.ac.uk/efo/EFO_0007845 GCST003644 Genome-wide genotyping array 2447 2017-02-23 27560520 Shaffer JR 2016-08-25 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/27560520 Genome-Wide Association Study Reveals Multiple Loci Influencing Normal Human Facial Morphology. Lower facial height 2,447 European ancestry individuals 671 European ancestry individuals Illumina [34985077] (imputed) 2 facial height measurement http://www.ebi.ac.uk/efo/EFO_0007856 GCST003645 Genome-wide genotyping array 2447 2017-02-23 27560520 Shaffer JR 2016-08-25 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/27560520 Genome-Wide Association Study Reveals Multiple Loci Influencing Normal Human Facial Morphology. Facial depth 2,447 European ancestry individuals 671 European ancestry individuals Illumina [34985077] (imputed) 7 facial depth measurement http://www.ebi.ac.uk/efo/EFO_0007857 GCST003646 Genome-wide genotyping array 2447 2017-02-10 27569725 Yang SK 2016-08-25 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/27569725 Identification of Loci at 1q21 and 16q23 That Affect Susceptibility to Inflammatory Bowel Disease in Koreans. Inflammatory bowel disease 1,505 Korean ancestry cases, 4,041 Korean ancestry controls 1,989 Korean ancestry cases, 3,491 Korean ancestry controls Illumina [522285] 15 inflammatory bowel disease http://www.ebi.ac.uk/efo/EFO_0003767 GCST003602 Genome-wide genotyping array 5546 2017-02-10 27558924 Kim HS 2016-08-24 Gut www.ncbi.nlm.nih.gov/pubmed/27558924 A coding variant in FTO confers susceptibility to thiopurine-induced leukopenia in East Asian patients with IBD. Thiopurine-induced leukopenia in inflammatory bowel disease 113 Korean ancestry cases, 154 Korean ancestry controls 245 East Asian ancestry cases, 522 East Asian ancestry controls Affymetrix [505014] 2 leukopenia, response to thiopurine http://www.ebi.ac.uk/efo/EFO_0004233, http://www.ebi.ac.uk/efo/EFO_0006317 GCST003603 Genome-wide genotyping array 267 2017-03-14 27568811 Marinelli M 2016-08-19 Sleep www.ncbi.nlm.nih.gov/pubmed/27568811 Heritability and Genome-Wide Association Analyses of Sleep Duration in Children: The EAGLE Consortium. Sleep duration 10,554 European ancestry children 1,250 European ancestry children Affymetrix, Illumina [at least 5306521] (imputed) 0 sleep duration http://www.ebi.ac.uk/efo/EFO_0005271 GCST003741 Genome-wide genotyping array 10554 2017-02-09 27545685 Biernacka JM 2016-08-03 Parkinsonism Relat Disord www.ncbi.nlm.nih.gov/pubmed/27545685 Genome-wide gene-environment interaction analysis of pesticide exposure and risk of Parkinson's disease. Parkinson's disease (pesticide exposure interaction) 364 cases, 364 sibling controls NA Perlegen [735843] (imputed) 1 Parkinson's disease, pesticide exposure measurement http://www.ebi.ac.uk/efo/EFO_0002508, http://www.ebi.ac.uk/efo/EFO_0007840 GCST003600 Genome-wide genotyping array 728 2017-03-11 27545300 Hao J 2016-08-22 Sci Rep www.ncbi.nlm.nih.gov/pubmed/27545300 A bivariate genome-wide association study identifies ADAM12 as a novel susceptibility gene for Kashin-Beck disease. Joint destruction and growth retardation 90 East Asian ancestry Kashin-Beck disease cases, 1,627 East Asian ancestry controls 403 East Asian ancestry Kashin-Beck disease cases, 297 East Asian ancestry controls Affymetrix [532894] 0 Kashin-Beck disease, joint damage measurement, height growth measurement http://www.ebi.ac.uk/efo/EFO_0006511, http://www.ebi.ac.uk/efo/EFO_0005413, http://www.ebi.ac.uk/efo/EFO_0005201 GCST003727 Genome-wide genotyping array 1717 2018-02-27 29382897 Pagerols M 2018-01-30 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29382897 Integrative genomic analysis of methylphenidate response in attention-deficit/hyperactivity disorder. Response to methylphenidate treatment in attention-deficit/hyperactivity disorder 141 European ancestry responder child cases, 32 European ancestry non-responder child cases 161 Brazilian responder cases, 28 Brazilian non-responder cases Illumina [3566199] (imputed) 0 response to methylphenidate http://purl.obolibrary.org/obo/GO_0036271 GCST005318 Genome-wide genotyping array 173 2018-10-22 27487801 Wu S 2016-11-01 Hum Genet www.ncbi.nlm.nih.gov/pubmed/27487801 Genome-wide scans reveal variants at EDAR predominantly affecting hair straightness in Han Chinese and Uyghur populations. Straight vs curly hair 2,675 Han Chinese ancestry cases, 224 Han Chinese ancestry controls 357 Uyghur ancestry cases, 352 Uyghur ancestry controls Illumina [81706044] (imputed) 2 hair morphology http://www.ebi.ac.uk/efo/EFO_0005038 GCST006468 Genome-wide genotyping array 2899 2017-03-11 27539887 Chahal HS 2016-08-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/27539887 Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma. Basal cell carcinoma 12.945 European ancestry cases, 274,252 European ancestry controls 4,242 European ancestry cases, 12,802 European ancestry controls Illumina [at least 560000] (imputed) 33 basal cell carcinoma http://www.ebi.ac.uk/efo/EFO_0004193 GCST003726 Genome-wide genotyping array 275209 2018-04-30 26367794 Zheng HF 2015-10-01 Nature www.ncbi.nlm.nih.gov/pubmed/26367794 Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture. Femoral neck bone mineral density 26,320 European ancestry individuals, 2,868 whole genome sequenced European ancestry individuals, 3,547 whole exome sequenced European ancestry individuals 17,253 European ancestry individuals Illumina [at least 10916125] (imputed) 3 femoral neck bone mineral density http://www.ebi.ac.uk/efo/EFO_0007785 GCST005544 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 32735 2018-04-30 26367794 Zheng HF 2015-10-01 Nature www.ncbi.nlm.nih.gov/pubmed/26367794 Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture. Lumbar spine bone mineral density 23,699 European ancestry individuals, 1,526 whole genome sequenced European ancestry individuals, 3,273 whole exome sequenced European ancestry individuals 16,233 European ancestry individuals Illumina [at least 10923926] (imputed) 4 spine bone mineral density http://www.ebi.ac.uk/efo/EFO_0007701 GCST005545 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 28498 2018-04-30 26367794 Zheng HF 2015-10-01 Nature www.ncbi.nlm.nih.gov/pubmed/26367794 Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture. Forearm bone mineral density 6,627 European ancestry individuals, 1,221 whole genome sequenced European ancestry individuals, 295 whole exome sequenced European ancestry individuals, 2,662 European ancestry individuals Illumina [at least 14018627] (imputed) 2 radius bone mineral density http://www.ebi.ac.uk/efo/EFO_0007933 GCST005546 Genome-wide genotyping array, Genome-wide sequencing, Exome-wide sequencing 8143 2018-03-29 29391395 Strawbridge RJ 2018-02-02 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29391395 Genome-wide analysis of self-reported risk-taking behaviour and cross-disorder genetic correlations in the UK Biobank cohort. Self-reported risk-taking behaviour 29,703 British ancestry cases, 86,552 British ancestry controls 35,210 British ancestry cases, 104,263 British ancestry controls Affymetrix [8781003] (imputed) 1 risk-taking behaviour http://www.ebi.ac.uk/efo/EFO_0008579 GCST005415 Genome-wide genotyping array 116255 2018-02-28 29395996 van Laarhoven A 2018-01-23 Lancet Infect Dis www.ncbi.nlm.nih.gov/pubmed/29395996 Cerebral tryptophan metabolism and outcome of tuberculous meningitis: an observational cohort study. CSF tryptophan concentration in tuberculous meningitis 130 individuals NA Illumina [4751257] (imputed) 10 tryptophan measurement http://www.ebi.ac.uk/efo/EFO_0008534 GCST005331 Genome-wide genotyping array 130 2018-04-04 29392897 Hernandez-Fuentes MP 2018-02-01 Am J Transplant www.ncbi.nlm.nih.gov/pubmed/29392897 Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study. Intracranial haemorrhage in renal transplantation (donors) 1,304 European ancestry donor cases, 8,784 European ancestry donor, recipient and other controls 2,407 European ancestry donor cases, 2,620 European ancestry donor controls Illumina [NR] 0 intracerebral hemorrhage http://www.ebi.ac.uk/efo/EFO_0005669 GCST005426 Genome-wide genotyping array 10088 2018-04-04 29392897 Hernandez-Fuentes MP 2018-02-01 Am J Transplant www.ncbi.nlm.nih.gov/pubmed/29392897 Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study. End stage renal failure in renal transplantation (recipient effect) 2,689 European ancestry recipient cases, 7,399 European ancestry donor and other controls 5,866 European ancestry individuals Illumina [NR] 0 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST005427 Genome-wide genotyping array 10088 2018-04-04 29392897 Hernandez-Fuentes MP 2018-02-01 Am J Transplant www.ncbi.nlm.nih.gov/pubmed/29392897 Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study. Graft survival time in renal transplantation (recipient effect) up to 2,689 European ancestry individuals 5,866 European ancestry individuals Illumina [NR] 0 renal transplant outcome measurement http://www.ebi.ac.uk/efo/EFO_0005199 GCST005428 Genome-wide genotyping array 2689 2018-04-04 29392897 Hernandez-Fuentes MP 2018-02-01 Am J Transplant www.ncbi.nlm.nih.gov/pubmed/29392897 Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study. Graft survival time in renal transplantation (donor effect) up to 2,204 European ancestry donors 5,027 European ancestry donors Illumina [NR] 0 renal transplant outcome measurement, donor genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0005199, http://www.ebi.ac.uk/efo/EFO_0007892 GCST005429 Genome-wide genotyping array 2204 2018-04-04 29392897 Hernandez-Fuentes MP 2018-02-01 Am J Transplant www.ncbi.nlm.nih.gov/pubmed/29392897 Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study. Graft survival time in renal transplantation (donor-recipient interaction) 2,094 European ancestry donor-recipient pairs 5,866 European ancestry donor-recipient pairs Illumina [NR] 0 renal transplant outcome measurement, donor genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0005199, http://www.ebi.ac.uk/efo/EFO_0007892 GCST005430 Genome-wide genotyping array 2094 2018-04-04 29392897 Hernandez-Fuentes MP 2018-02-01 Am J Transplant www.ncbi.nlm.nih.gov/pubmed/29392897 Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study. Acute graft rejection in renal transplantation (recipient effect) 441 European ancestry cases, 941 European ancestry controls 575 European ancestry cases, 2,573 European ancestry controls Illumina [NR] 0 renal transplant outcome measurement http://www.ebi.ac.uk/efo/EFO_0005199 GCST005431 Genome-wide genotyping array 1382 2018-04-04 29392897 Hernandez-Fuentes MP 2018-02-01 Am J Transplant www.ncbi.nlm.nih.gov/pubmed/29392897 Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study. Acute graft rejection in renal transplantation (donor effect) 414 European ancestry donors (rejection outcome), 825 European ancestry donors (no rejection outcome) 575 European ancestry donors (rejection outcome), 2,573 European ancestry donors (no rejection outcome) Illumina [NR] 0 renal transplant outcome measurement, donor genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0005199, http://www.ebi.ac.uk/efo/EFO_0007892 GCST005432 Genome-wide genotyping array 1239 2018-04-04 29392897 Hernandez-Fuentes MP 2018-02-01 Am J Transplant www.ncbi.nlm.nih.gov/pubmed/29392897 Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study. Acute graft rejection in renal transplantation (donor-recipient interaction) 343 European ancestry recipient-donor pair cases, 755 European ancestry recipient-donor pair controls 575 European ancestry recipient-donor pair cases, 2,573 European ancestry recipient-donor pair controls Illumina [NR] 0 renal transplant outcome measurement, donor genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0005199, http://www.ebi.ac.uk/efo/EFO_0007892 GCST005433 Genome-wide genotyping array 1098 2018-06-12 29495898 Peterson RE 2018-03-02 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/29495898 Molecular Genetic Analysis Subdivided by Adversity Exposure Suggests Etiologic Heterogeneity in Major Depression. Major depressive disorder 4,785 Han Chinese ancestry cases, 4,814 Han Chinese ancestry controls NA NR [4313801] (imputed) 3 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST005691 Genome-wide genotyping array 9599 2018-06-12 29495898 Peterson RE 2018-03-02 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/29495898 Molecular Genetic Analysis Subdivided by Adversity Exposure Suggests Etiologic Heterogeneity in Major Depression. Major depressive disorder (exposed to adversity) 1,646 Han Chinese ancestry cases, 982 Han Chinese ancestry controls NA NR [4313801] (imputed) 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST005690 Genome-wide genotyping array 2628 2018-06-12 29495898 Peterson RE 2018-03-02 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/29495898 Molecular Genetic Analysis Subdivided by Adversity Exposure Suggests Etiologic Heterogeneity in Major Depression. Major depressive disorder (unexposed to adversity) 3,139 Han Chinese ancestry cases, 3,832 Han Chinese ancestry controls NA NR [4313801] (imputed) 4 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST005689 Genome-wide genotyping array 6971 2018-03-01 29397368 Meng W 2018-01-31 EBioMedicine www.ncbi.nlm.nih.gov/pubmed/29397368 A Genome-Wide Association Study Finds Genetic Associations with Broadly-Defined Headache in UK Biobank (N=223,773). Headache 74,461 British ancestry cases, 149,321 British ancestry controls NA Affymetrix [9304965] (imputed) 28 Headache http://purl.obolibrary.org/obo/HP_0002315 GCST005337 Genome-wide genotyping array 223782 2018-06-29 29494758 Liu L 2018-03-01 Br J Dermatol www.ncbi.nlm.nih.gov/pubmed/29494758 Genome-wide association study identifies three novel susceptibility loci for systemic lupus erythematosus in Han Chinese. Systemic lupus erythematosus 1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls 3,509 Han Chinese ancestry cases, 8,246 Han Chinese ancestry controls NR [at least 493955] (imputed) 3 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST005754 Genome-wide genotyping array 2252 2018-03-12 29398083 Lores-Motta L 2018-02-01 Ophthalmology www.ncbi.nlm.nih.gov/pubmed/29398083 Genome-Wide Association Study Reveals Variants in CFH and CFHR4 Associated with Systemic Complement Activation: Implications in Age-Related Macular Degeneration. Serum C3d:C3 ratio (systemic complement activation) up to 1,548 European ancestry individuals up to 697 European ancestry individuals Illumina [9972920] (imputed) 2 c3d:C3 ratio http://www.ebi.ac.uk/efo/EFO_0008543 GCST005365 Genome-wide genotyping array 1548 2018-06-29 29496196 McCoy TH Jr. 2018-02-20 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/29496196 Genome-wide Association Study of Dimensional Psychopathology Using Electronic Health Records. Dimensional psychopathology (Negative) 4,687 Northern European ancestry individuals NA Illumina [893900] (imputed) 10 negative domain measurement http://www.ebi.ac.uk/efo/EFO_0009096 GCST005756 Genome-wide genotyping array 4687 2018-06-29 29496196 McCoy TH Jr. 2018-02-20 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/29496196 Genome-wide Association Study of Dimensional Psychopathology Using Electronic Health Records. Dimensional psychopathology (Positive) 4,687 Northern European ancestry individuals NA Illumina [893900] (imputed) 10 positive domain measurement http://www.ebi.ac.uk/efo/EFO_0009097 GCST005757 Genome-wide genotyping array 4687 2018-06-29 29496196 McCoy TH Jr. 2018-02-20 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/29496196 Genome-wide Association Study of Dimensional Psychopathology Using Electronic Health Records. Dimensional psychopathology (Arousal) 4,687 Northern European ancestry individuals NA Illumina [893900] (imputed) 10 arousal domain measurement http://www.ebi.ac.uk/efo/EFO_0009099 GCST005758 Genome-wide genotyping array 4687 2018-06-29 29496196 McCoy TH Jr. 2018-02-20 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/29496196 Genome-wide Association Study of Dimensional Psychopathology Using Electronic Health Records. Dimensional psychopathology (Social) 4,687 Northern European ancestry individuals NA Illumina [893900] (imputed) 10 social domain measurement http://www.ebi.ac.uk/efo/EFO_0009100 GCST005759 Genome-wide genotyping array 4687 2018-06-29 29496196 McCoy TH Jr. 2018-02-20 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/29496196 Genome-wide Association Study of Dimensional Psychopathology Using Electronic Health Records. Dimensional psychopathology (Cognitive) 4,687 Northern European ancestry individuals NA Illumina [893900] (imputed) 10 cognitive domain measurement http://www.ebi.ac.uk/efo/EFO_0009098 GCST005760 Genome-wide genotyping array 4687 2019-01-11 26401656 Burkhardt R 2015-09-24 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/26401656 Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood. Blood metabolite levels 2,107 European ancestry individuals 923 Sorbian (founder/genetic isolate) individuals Affymetrix [2619023] (imputed) 25 blood metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005664 GCST006879 Genome-wide genotyping array 2107 2017-03-31 27701424 Castano-Betancourt MC 2016-10-04 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/27701424 Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis. Hip minimal joint space width 6,523 European ancestry individuals, 6,490 individuals 1,572 European ancestry individuals, 6,655 individuals Illumina [2385183] (imputed) 9 cartilage thickness measurement http://www.ebi.ac.uk/efo/EFO_0007873 GCST003853 Genome-wide genotyping array 13013 2018-12-17 22833195 Terracciano A 2011-10-18 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/22833195 Meta-analysis of genome-wide association studies identifies common variants in CTNNA2 associated with excitement-seeking. Excitement-seeking behaviour 4,375 Sardinian (founder/genetic isolate) individuals, 343 Cilento (founder/genetic isolate) individuals, 3,142 European ancestry individuals 2,062 European ancestry individuals, 3,043 individuals Affymetrix, Illumina [at least 2000000] (imputed) 0 personality trait measurement http://www.ebi.ac.uk/efo/EFO_0007911 GCST006796 Genome-wide genotyping array 7860 2017-12-18 29066854 Lin BD 2017-11-01 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29066854 2SNP heritability and effects of genetic variants for neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio. Platelet-to-lymphocyte ratio 5,901 Dutch ancestry individuals 2,538 individuals Affymetrix, Illumina, Perlegen [6010458] (imputed) 0 platelet-to-lymphocyte ratio http://www.ebi.ac.uk/efo/EFO_0008446 GCST005052 Genome-wide genotyping array 5901 2017-12-18 29066854 Lin BD 2017-11-01 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29066854 2SNP heritability and effects of genetic variants for neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio. Neutrophil count 5,901 Dutch ancestry individuals 2,538 individuals Affymetrix, Illumina, Perlegen [6010458] (imputed) 1 neutrophil count http://www.ebi.ac.uk/efo/EFO_0004833 GCST005056 Genome-wide genotyping array 5901 2017-12-18 29066854 Lin BD 2017-11-01 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29066854 2SNP heritability and effects of genetic variants for neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio. Lymphocyte counts 5,901 Dutch ancestry individuals 2,538 individuals Affymetrix, Illumina, Perlegen [6010458] (imputed) 0 lymphocyte count http://www.ebi.ac.uk/efo/EFO_0004587 GCST005055 Genome-wide genotyping array 5901 2017-12-18 29066854 Lin BD 2017-11-01 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29066854 2SNP heritability and effects of genetic variants for neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio. Platelet count 5,901 Dutch ancestry individuals 2,538 individuals Affymetrix, Illumina, Perlegen [6010458] (imputed) 5 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST005054 Genome-wide genotyping array 5901 2017-12-18 29066854 Lin BD 2017-11-01 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29066854 2SNP heritability and effects of genetic variants for neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio. Neutrophil-to-lymphocyte ratio 5,901 Dutch ancestry individuals 2,538 individuals Affymetrix, Illumina, Perlegen [6010458] (imputed) 0 neutrophil-to-lymphocyte ratio http://www.ebi.ac.uk/efo/EFO_0008447 GCST005053 Genome-wide genotyping array 5901 2017-12-11 21908519 Huffman JE 2011-12-15 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21908519 Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults. N-glycan levels Up to 1,426 European ancestry male individuals, up to 1,941 European ancestry female individuals NA Illumina [NR] 41 N-glycan measurement http://www.ebi.ac.uk/efo/EFO_0004999 GCST005046 Genome-wide genotyping array 3367 2017-11-30 29057527 Ballantine JL 2017-10-23 Int J Paediatr Dent www.ncbi.nlm.nih.gov/pubmed/29057527 Exploring the genomic basis of early childhood caries: a pilot study. Early childhood caries 26 African American cases, 34 Hispanic cases, 13 European ancestry cases, 6 Native-American ancestry cases, 1 case, 41 African American controls, 40 Hispanic controls, 36 European ancestry controls, 15 Native-American ancestry controls. 265 cases, 656 controls Illumina [~ 1400000] 0 dental caries http://www.ebi.ac.uk/efo/EFO_0003819 GCST004989 Genome-wide genotyping array 212 2018-07-12 28779025 Alberts R 2017-08-04 Gut www.ncbi.nlm.nih.gov/pubmed/28779025 Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis. Autoimmune hepatitis in primary sclerosing cholangitis 107 European ancestry cases, 3,159 European ancestry controls NA Illumina [130422] (imputed) 3 Autoimmune Hepatitis http://www.ebi.ac.uk/efo/EFO_0005676 GCST005853 Targeted genotyping array [ImmunoChip] 3266 2018-07-12 28779025 Alberts R 2017-08-04 Gut www.ncbi.nlm.nih.gov/pubmed/28779025 Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis. Primary sclerosing cholangitis (small duct vs large duct) 75 European ancestry small duct cases, 3,159 European ancestry large duct cases NA Illumina [130422] 0 sclerosing cholangitis http://www.ebi.ac.uk/efo/EFO_0004268 GCST005854 Targeted genotyping array [ImmunoChip] 3234 2018-07-12 28779025 Alberts R 2017-08-04 Gut www.ncbi.nlm.nih.gov/pubmed/28779025 Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis. Liver transplant-free survival in primary sclerosing cholangitis (time to event) 874 European ancestry liver transplantation cases , 2,444 European ancestry liver transplant-free cases NA Illumina [130422] 3 event free survival time, sclerosing cholangitis http://www.ebi.ac.uk/efo/EFO_0000482, http://www.ebi.ac.uk/efo/EFO_0004268 GCST005859 Targeted genotyping array [ImmunoChip] 3318 2018-07-12 28779025 Alberts R 2017-08-04 Gut www.ncbi.nlm.nih.gov/pubmed/28779025 Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis. Colectomy in primary sclerosing cholangitis 419 European ancestry colectomy cases, 2,897 European non-colectomy controls NA Illumina [130422] 0 sclerosing cholangitis http://www.ebi.ac.uk/efo/EFO_0004268 GCST005852 Targeted genotyping array [ImmunoChip] 3316 2018-07-12 28779025 Alberts R 2017-08-04 Gut www.ncbi.nlm.nih.gov/pubmed/28779025 Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis. Cholangiocarcinoma in primary sclerosing cholangitis 188 European ancestry cases, 3,147 European ancestry controls NA Illumina [130422] 1 cholangiocarcinoma http://www.ebi.ac.uk/efo/EFO_0005221 GCST005855 Targeted genotyping array [ImmunoChip] 3335 2018-07-12 28779025 Alberts R 2017-08-04 Gut www.ncbi.nlm.nih.gov/pubmed/28779025 Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis. Cholangiocarcinoma in primary sclerosing cholangitis (time to event) 188 European ancestry cholangiocarcinoma cases, 3,147 European ancestry cholangiocarcinoma-free cases NA Illumina [130422] 3 event free survival time, cholangiocarcinoma, sclerosing cholangitis http://www.ebi.ac.uk/efo/EFO_0000482, http://www.ebi.ac.uk/efo/EFO_0005221, http://www.ebi.ac.uk/efo/EFO_0004268 GCST005860 Targeted genotyping array [ImmunoChip] 3335 2018-07-12 28779025 Alberts R 2017-08-04 Gut www.ncbi.nlm.nih.gov/pubmed/28779025 Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis. Colorectal carcinoma in primary sclerosing cholangitis 127 European ancestry cases, 2,822 European ancestry controls NA Illumina [130422] 1 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST005856 Targeted genotyping array [ImmunoChip] 2949 2018-07-12 28779025 Alberts R 2017-08-04 Gut www.ncbi.nlm.nih.gov/pubmed/28779025 Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis. Gallbladder carcinoma in primary sclerosing cholangitis 30 European ancestry cases, 2,977 European ancestry controls NA Illumina [130422] 0 gallbladder neoplasm http://www.ebi.ac.uk/efo/EFO_0004606 GCST005857 Targeted genotyping array [ImmunoChip] 3007 2018-07-12 28779025 Alberts R 2017-08-04 Gut www.ncbi.nlm.nih.gov/pubmed/28779025 Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis. Hepatocellular carcinoma in primary sclerosing cholangitis 22 European ancestry cases, 2,984 European ancestry controls NA Illumina [130422] 0 hepatocellular carcinoma http://www.ebi.ac.uk/efo/EFO_0000182 GCST005858 Targeted genotyping array [ImmunoChip] 3006 2017-11-14 25751625 Michailidou K 2015-04-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/25751625 Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer. Breast cancer 15,748 European ancestry cases, 18,084 European ancestry controls 46,785 European ancestry cases, 42,892 European ancestry controls Affymetrix, Illumina [~ 11600000] (imputed) 88 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST004950 Genome-wide genotyping array 33832 2019-02-28 25751625 Michailidou K 2015-04-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/25751625 Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer. Breast cancer 46,785 European ancestry cases, 42,892 European ancestry controls NA Affymetrix, Illumina [~ 14000000] (imputed) 74 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST007236 Genome-wide genotyping array 89677 2018-01-12 29146897 Pirastu N 2017-11-17 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29146897 GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk. Male-pattern baldness 25,662 British ancestry cases, 17,928 British ancestry controls 13,367 European ancestry cases, 11,851 European ancestry controls, 3,436 cases, 2,435 controls Affymetrix [27512692] (imputed) 58 androgenetic alopecia http://www.ebi.ac.uk/efo/EFO_0004191 GCST005116 Genome-wide genotyping array 43590 2019-01-22 29500382 Nagel M 2018-03-02 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29500382 Item-level analyses reveal genetic heterogeneity in neuroticism. Neurociticism 380,506 European ancestry individuals NA NR [10847151] (imputed) 181 neuroticism measurement http://www.ebi.ac.uk/efo/EFO_0007660 GCST006940 Genome-wide genotyping array 380506 2019-01-22 29500382 Nagel M 2018-03-02 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29500382 Item-level analyses reveal genetic heterogeneity in neuroticism. Irritable mood 366,726 European ancestry individuals NA NR [~ 10847151] (imputed) 67 irritability measurement http://www.ebi.ac.uk/efo/EFO_0009594 GCST006941 Genome-wide genotyping array 366726 2019-01-22 29500382 Nagel M 2018-03-02 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29500382 Item-level analyses reveal genetic heterogeneity in neuroticism. Feeling lonely 376,352 European ancestry individuals NA NR [10847151] (imputed) 10 loneliness measurement http://www.ebi.ac.uk/efo/EFO_0007865 GCST006942 Genome-wide genotyping array 376352 2019-01-22 29500382 Nagel M 2018-03-02 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29500382 Item-level analyses reveal genetic heterogeneity in neuroticism. Feeling miserable 376,097 European ancestry individuals NA NR [10847151] (imputed) 64 feeling miserable measurement http://www.ebi.ac.uk/efo/EFO_0009598 GCST006943 Genome-wide genotyping array 376097 2019-01-22 29500382 Nagel M 2018-03-02 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29500382 Item-level analyses reveal genetic heterogeneity in neuroticism. Experiencing mood swings 373,733 European ancestry individuals NA NR [10847151] (imputed) 69 mood instability measurement http://www.ebi.ac.uk/efo/EFO_0008475 GCST006944 Genome-wide genotyping array 373733 2019-01-22 29500382 Nagel M 2018-03-02 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29500382 Item-level analyses reveal genetic heterogeneity in neuroticism. Feeling guilty 373,380 European ancestry individuals NA NR [10847151] (imputed) 29 guilt measurement http://www.ebi.ac.uk/efo/EFO_0009595 GCST006945 Genome-wide genotyping array 373380 2019-01-22 29500382 Nagel M 2018-03-02 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29500382 Item-level analyses reveal genetic heterogeneity in neuroticism. Worry too long after an embarrassing experience 367,725 European ancestry individuals NA NR [10847151] (imputed) 34 worry measurement http://www.ebi.ac.uk/efo/EFO_0009589 GCST006946 Genome-wide genotyping array 367725 2019-01-22 29500382 Nagel M 2018-03-02 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29500382 Item-level analyses reveal genetic heterogeneity in neuroticism. Feeling fed-up 374,971 European ancestry individuals NA NR [10847151] (imputed) 60 "feeling ""fed-up"" measurement" http://www.ebi.ac.uk/efo/EFO_0009588 GCST006947 Genome-wide genotyping array 374971 2019-01-22 29500382 Nagel M 2018-03-02 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29500382 Item-level analyses reveal genetic heterogeneity in neuroticism. Feeling nervous 373,121 European ancestry individuals NA NR [10847151] (imputed) 67 feeling nervous measurement http://www.ebi.ac.uk/efo/EFO_0009597 GCST006948 Genome-wide genotyping array 373121 2019-01-22 29500382 Nagel M 2018-03-02 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29500382 Item-level analyses reveal genetic heterogeneity in neuroticism. Suffering from nerves 369,499 European ancestry individuals NA NR [10847151] (imputed) 12 nervousness http://purl.obolibrary.org/obo/NCIT_C74532 GCST006949 Genome-wide genotyping array 369499 2019-01-22 29500382 Nagel M 2018-03-02 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29500382 Item-level analyses reveal genetic heterogeneity in neuroticism. Feeling worry 372,869 European ancestry individuals NA NR [10847151] (imputed) 71 worry measurement http://www.ebi.ac.uk/efo/EFO_0009589 GCST006950 Genome-wide genotyping array 372869 2019-01-22 29500382 Nagel M 2018-03-02 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29500382 Item-level analyses reveal genetic heterogeneity in neuroticism. Feeling hurt 372,047 European ancestry individuals NA NR [10847151] (imputed) 46 feeling emotionally hurt measurement http://www.ebi.ac.uk/efo/EFO_0009599 GCST006951 Genome-wide genotyping array 372047 2019-01-22 29500382 Nagel M 2018-03-02 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29500382 Item-level analyses reveal genetic heterogeneity in neuroticism. Feeling tense 371,318 European ancestry individuals NA NR [10847151] (imputed) 33 feeling tense measurement http://www.ebi.ac.uk/efo/EFO_0009596 GCST006952 Genome-wide genotyping array 371318 2019-08-21 25854761 Zuo X 2015-04-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25854761 Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis. Psoriasis 11,245 Han Chinese ancestry cases, 11,177 Han Chinese ancestry controls 6,369 Han Chinese ancestry cases, 13,969 Han Chinese ancestry controls Illumina [87827] 34 psoriasis http://www.ebi.ac.uk/efo/EFO_0000676 GCST008479 Exome genotyping array [Exome array] 22422 2019-08-14 25771307 Watson AL 2015-02-26 Diabetes Res Clin Pract www.ncbi.nlm.nih.gov/pubmed/25771307 Single nucleotide polymorphisms in type 2 diabetes among Hispanic adults. Type 2 diabetes 18 Hispanic cases, 18 Hispanic controls NA Illumina [132623] 0 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST008434 Targeted genotyping array [Cardio-MetaboChip] 36 2017-01-27 27191271 Hu Q 2016-05-13 Oncotarget www.ncbi.nlm.nih.gov/pubmed/27191271 NPR-C gene polymorphism is associated with increased susceptibility to coronary artery disease in Chinese Han population: a multicenter study. Coronary artery disease 393 Han Chinese ancestry cases, 393 Han Chinese ancestry controls 4,537 Han Chinese ancestry cases, 4,590 Han Chinese ancestry controls Illumina [872261] 0 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST003561 Genome-wide genotyping array 786 2017-12-19 27029810 Joshi PK 2016-03-31 Nat Commun www.ncbi.nlm.nih.gov/pubmed/27029810 Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan. Mortality 138,536 British ancestry mothers, 133,545 British ancestry fathers 24,168 European ancestry individuals, 681 African ancestry individuals, 962 Afro-Caribbean individuals, 1,613 South Asian ancestry individuals, 338 Chinese ancestry individuals Affymetrix [73355667] (imputed) 2 mortality http://www.ebi.ac.uk/efo/EFO_0004352 GCST005078 Genome-wide genotyping array 272081 2017-12-05 29065852 Hallengren E 2017-10-24 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/29065852 Genetic determinants of growth hormone and GH-related phenotypes. Fasting growth hormone levels 4,134 Swedish ancestry individuals 5,262 Swedish ancestry individuals Illumina [659208] 0 growth hormone measurement http://www.ebi.ac.uk/efo/EFO_0008438 GCST005035 Genome-wide genotyping array 4134 2018-07-30 27618447 Surendran P 2016-10-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27618447 Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Diastolic blood pressure up to 165,276 European ancestry individuals, up to 27,487 South Asian ancestry individuals up to 125,713 European ancestry individuals, up to 2,641 South Asian ancestry individuals, 4,632 Hispanic individuals, 22,077 African American individuals Illumina [242296] 44 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST006020 Targeted genotyping array [Exome array] 192763 2018-07-30 27618447 Surendran P 2016-10-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27618447 Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Systolic blood pressure up to 165,276 European ancestry individuals, up to 27,487 South Asian ancestry individuals up to 125,713 European ancestry individuals, up to 2,641 South Asian ancestry individuals, 4,632 Hispanic individuals, 22,077 African American individuals Illumina [242296] 45 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST006021 Targeted genotyping array [Exome array] 192763 2018-07-30 27618447 Surendran P 2016-10-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27618447 Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Pulse pressure up to 165,276 European ancestry individuals, up to 27,487 South Asian ancestry individuals up to 125,713 European ancestry individuals, up to 2,641 South Asian ancestry individuals, 4,632 Hispanic individuals, 22,077 African American individuals Illumina [242296] 17 pulse pressure measurement http://www.ebi.ac.uk/efo/EFO_0005763 GCST006022 Targeted genotyping array [Exome array] 192763 2018-07-30 27618447 Surendran P 2016-10-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27618447 Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Hypertension up to 83,330 European ancestry cases, up to 73,760 European ancestry controls, up to 9,322 South Asian ancestry cases, up to 16,861 South Asian ancestry controls up to 125,713 European ancestry individuals, up to 2,641 South Asian ancestry individuals, 4,632 Hispanic individuals, 22,077 African American individuals Illumina [242296] 12 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST006023 Targeted genotyping array [Exome array] 183273 2018-01-30 29273806 Demenais F 2017-12-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29273806 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. Asthma 19,954 European ancestry cases, 107,715 European ancestry controls, 2,149 African ancestry cases, 6,055 African ancestry controls, 1,239 Japanese ancestry cases, 3,976 Japanese ancestry controls, 606 Latino cases, 792 Latino controls NA Affymetrix, Illumina, Perlegen [2831075] (imputed) 40 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST005212 Genome-wide genotyping array 142486 2018-01-30 29273806 Demenais F 2017-12-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29273806 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. Asthma (childhood onset) 7,131 European ancestry cases, 13,631 European ancestry controls, 1,239 Japanese ancestry cases, 3,976 Japanese ancestry controls, 606 Latino cases, 792 Latino controls NA Affymetrix, Illumina, Perlegen [2831075] (imputed) 5 childhood onset asthma http://www.ebi.ac.uk/efo/EFO_0004591 GCST005213 Genome-wide genotyping array 27375 2019-01-09 29273806 Demenais F 2017-12-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29273806 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. Asthma 19,954 European ancestry cases, 107,715 European ancestry controls NA Affymetrix, Illumina, Perlegen [2831075] (imputed) 24 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST006862 Genome-wide genotyping array 127669 2018-07-12 29773799 Horikoshi M 2018-05-17 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29773799 Elucidating the genetic architecture of reproductive ageing in the Japanese population. Menopause (age at onset) 43,861 Japanese ancestry women 32,545 European ancestry women Illumina [at least 532488] (imputed) 36 age at menopause http://www.ebi.ac.uk/efo/EFO_0004704 GCST005863 Genome-wide genotyping array 43861 2018-07-12 29773799 Horikoshi M 2018-05-17 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29773799 Elucidating the genetic architecture of reproductive ageing in the Japanese population. Menarche (age at onset) 67,029 Japanese ancestry women 73,397 European ancestry women Illumina [at least 532488] (imputed) 31 age at menarche http://www.ebi.ac.uk/efo/EFO_0004703 GCST005867 Genome-wide genotyping array 67029 2018-07-12 29773799 Horikoshi M 2018-05-17 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29773799 Elucidating the genetic architecture of reproductive ageing in the Japanese population. Early age at menarche 15,709 Japanese ancestry early age at menarche individuals, 14,557 Japanese ancestry median age at menarche individuals NA Illumina [at least 532488] (imputed) 1 age at menarche http://www.ebi.ac.uk/efo/EFO_0004703 GCST005865 Genome-wide genotyping array 30266 2018-07-12 29773799 Horikoshi M 2018-05-17 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29773799 Elucidating the genetic architecture of reproductive ageing in the Japanese population. Late age at menarche 10,875 Japanese ancestry late age at menarche individuals, 14,557 Japanese ancestry median age at menarche individuals NA Illumina [at least 532488] (imputed) 0 age at menarche http://www.ebi.ac.uk/efo/EFO_0004703 GCST005864 Genome-wide genotyping array 25432 2018-06-19 29521573 Buck D 2018-03-01 Mult Scler www.ncbi.nlm.nih.gov/pubmed/29521573 Effect of HLA-DRB1 alleles and genetic variants on the development of neutralizing antibodies to interferon beta in the BEYOND and BENEFIT trials. Neutralising antibody response to interferon beta therapy in multiple sclerosis (time to production) 361 European, Hispanic, Asian, African or unknown ancestry cases NA Affymetrix [8671751] (imputed) 0 response to interferon beta, anti-drug antibody measurement http://purl.obolibrary.org/obo/GO_0035456, http://www.ebi.ac.uk/efo/EFO_0010559 GCST005710 Genome-wide genotyping array 361 2018-06-19 29521573 Buck D 2018-03-01 Mult Scler www.ncbi.nlm.nih.gov/pubmed/29521573 Effect of HLA-DRB1 alleles and genetic variants on the development of neutralizing antibodies to interferon beta in the BEYOND and BENEFIT trials. Neutralising antibody response to interferon beta therapy in multiple sclerosis (presence of antibodies) 361 European, Hispanic, Asian, African or unknown ancestry cases, 580 European, Hispanic, Asian, African or unknown ancestry controls NA Affymetrix [8671751] (imputed) 1 response to interferon beta, anti-drug antibody measurement http://purl.obolibrary.org/obo/GO_0035456, http://www.ebi.ac.uk/efo/EFO_0010559 GCST005706 Genome-wide genotyping array 941 2018-06-19 29521573 Buck D 2018-03-01 Mult Scler www.ncbi.nlm.nih.gov/pubmed/29521573 Effect of HLA-DRB1 alleles and genetic variants on the development of neutralizing antibodies to interferon beta in the BEYOND and BENEFIT trials. Neutralising antibody response to interferon beta therapy in multiple sclerosis (mean antibody levels) 926 European ancestry individuals, 7 Hispanic individuals, 1 Asian ancestry individuals, 1 African ancestry individual, 4 other unknown ancestry individuals, 2 individuals NA Affymetrix [8671751] (imputed) 1 response to interferon beta, anti-drug antibody measurement http://purl.obolibrary.org/obo/GO_0035456, http://www.ebi.ac.uk/efo/EFO_0010559 GCST005707 Genome-wide genotyping array 941 2018-06-19 29521573 Buck D 2018-03-01 Mult Scler www.ncbi.nlm.nih.gov/pubmed/29521573 Effect of HLA-DRB1 alleles and genetic variants on the development of neutralizing antibodies to interferon beta in the BEYOND and BENEFIT trials. Neutralising antibody response to interferon beta therapy in multiple sclerosis (area under the curve for the first two years) 926 European ancestry individuals, 7 Hispanic individuals, 1 Asian ancestry individuals, 1 African ancestry individual, 4 other unknown ancestry individuals, 2 individuals NA Affymetrix [8671751] (imputed) 1 response to interferon beta, anti-drug antibody measurement http://purl.obolibrary.org/obo/GO_0035456, http://www.ebi.ac.uk/efo/EFO_0010559 GCST005708 Genome-wide genotyping array 941 2018-06-19 29521573 Buck D 2018-03-01 Mult Scler www.ncbi.nlm.nih.gov/pubmed/29521573 Effect of HLA-DRB1 alleles and genetic variants on the development of neutralizing antibodies to interferon beta in the BEYOND and BENEFIT trials. Neutralising antibody response to interferon beta therapy in multiple sclerosis (maximum antibody levels) 926 European ancestry individuals, 7 Hispanic individuals, 1 Asian ancestry individuals, 1 African ancestry individual, 4 other unknown ancestry individuals, 2 individuals NA Affymetrix [8671751] (imputed) 1 response to interferon beta, anti-drug antibody measurement http://purl.obolibrary.org/obo/GO_0035456, http://www.ebi.ac.uk/efo/EFO_0010559 GCST005709 Genome-wide genotyping array 941 2018-03-05 29304378 Medina-Gomez C 2018-01-04 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29304378 Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. Total body bone mineral density 56,284 European ancestry individuals, up to 1,333 African American individuals, up to 9,328 admixed individuals NA Affymetrix, Illumina [~ 23700000] (imputed) 242 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST005348 Genome-wide genotyping array 66945 2018-03-05 29304378 Medina-Gomez C 2018-01-04 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29304378 Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. Total body bone mineral density (age 0-15) 11,807 European and unknown ancestry individuals NA Affymetrix, Illumina [~ 23700000] (imputed) 8 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST005345 Genome-wide genotyping array 11807 2018-03-05 29304378 Medina-Gomez C 2018-01-04 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29304378 Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. Total body bone mineral density (age 15-30) 4,180 European and unknown ancestry individuals NA Affymetrix, Illumina [~ 23700000] (imputed) 1 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST005344 Genome-wide genotyping array 4180 2018-03-05 29304378 Medina-Gomez C 2018-01-04 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29304378 Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. Total body bone mineral density (age 30-45) 10,062 European and unknown ancestry individuals NA Affymetrix, Illumina [~ 23700000] (imputed) 8 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST005346 Genome-wide genotyping array 10062 2018-03-05 29304378 Medina-Gomez C 2018-01-04 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29304378 Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. Total body bone mineral density (age 45-60) 18,805 European individuals NA Affymetrix, Illumina [~ 23700000] (imputed) 18 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST005350 Genome-wide genotyping array 18805 2018-03-05 29304378 Medina-Gomez C 2018-01-04 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29304378 Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. Total body bone mineral density (age over 60) 22,504 European ancestry and African American individuals NA Affymetrix, Illumina [~ 23700000] (imputed) 20 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST005349 Genome-wide genotyping array 22504 2018-04-06 29404672 Roshandel D 2018-02-05 Diabetologia www.ncbi.nlm.nih.gov/pubmed/29404672 Meta-genome-wide association studies identify a locus on chromosome 1 and multiple variants in the MHC region for serum C-peptide in type 1 diabetes. Stimulated C-peptide levels in type I diabetes 1,303 European ancestry individuals NA Illumina [8978838] (imputed) 2 C-peptide measurement http://www.ebi.ac.uk/efo/EFO_0005187 GCST005435 Genome-wide genotyping array 1303 2018-04-06 29404672 Roshandel D 2018-02-05 Diabetologia www.ncbi.nlm.nih.gov/pubmed/29404672 Meta-genome-wide association studies identify a locus on chromosome 1 and multiple variants in the MHC region for serum C-peptide in type 1 diabetes. Fasting C-peptide levels in type I diabetes 2,019 European ancestry individuals NA Illumina [8375292] (imputed) 0 C-peptide measurement http://www.ebi.ac.uk/efo/EFO_0005187 GCST005438 Genome-wide genotyping array 2019 2018-04-06 29404672 Roshandel D 2018-02-05 Diabetologia www.ncbi.nlm.nih.gov/pubmed/29404672 Meta-genome-wide association studies identify a locus on chromosome 1 and multiple variants in the MHC region for serum C-peptide in type 1 diabetes. Random C-peptide levels in type I diabetes 1,497 European ancestry individuals NA Illumina [8320327] (imputed) 1 C-peptide measurement http://www.ebi.ac.uk/efo/EFO_0005187 GCST005437 Genome-wide genotyping array 1497 2018-04-06 29404672 Roshandel D 2018-02-05 Diabetologia www.ncbi.nlm.nih.gov/pubmed/29404672 Meta-genome-wide association studies identify a locus on chromosome 1 and multiple variants in the MHC region for serum C-peptide in type 1 diabetes. C-peptide levels in type I diabetes 3,479 European ancestry individuals NA Illumina [7988630] (imputed) 4 C-peptide measurement http://www.ebi.ac.uk/efo/EFO_0005187 GCST005436 Genome-wide genotyping array 3479 2018-04-06 29422604 Klein AP 2018-02-08 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29422604 Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer. Pancreatic cancer 9,040 European ancestry cases, 12,496 European ancestry controls up to 2,737 cases, up to 4,752 controls Illumina [11381182] (imputed) 32 pancreatic carcinoma http://www.ebi.ac.uk/efo/EFO_0002618 GCST005434 Genome-wide genotyping array 21536 2018-09-06 25817017 Carmona FD 2015-03-26 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/25817017 A large-scale genetic analysis reveals a strong contribution of the HLA class II region to giant cell arteritis susceptibility. Giant cell arteritis 1,651 European ancestry cases, 15,306 European ancestry controls NA Illumina [95416] 3 temporal arteritis http://www.ebi.ac.uk/efo/EFO_1001209 GCST006198 Targeted genotyping array [ImmunoChip] 16957 2018-05-11 29246937 Li Y 2018-02-15 Clin Cancer Res www.ncbi.nlm.nih.gov/pubmed/29246937 Genome-Wide Association Study Identifies a New Locus at 7q21.13 Associated with Hepatitis B Virus-Related Hepatocellular Carcinoma. Hepatitis B virus-related hepatocellular carcinoma 348 Chinese ancestry carrier cases, 359 Chinese ancestry carrier controls, 189 Chinese ancestry trios 3,796 Chinese ancestry carrier cases, 2,544 Chinese ancestry carrier controls Affymetrix, Illumina [up to 6089459] (imputed) 2 hepatitis B virus infection, hepatocellular carcinoma http://www.ebi.ac.uk/efo/EFO_0004197, http://www.ebi.ac.uk/efo/EFO_0000182 GCST005570 Genome-wide genotyping array 896 2017-10-20 28960316 Tanskanen T 2017-09-28 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/28960316 Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci. Colorectal cancer 1,701 Finnish ancestry cases, 14,082 Finnish ancestry controls 11,647 European ancestry cases, 12,356 European ancestry controls Illumina [9068015] (imputed) 5 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST004895 Genome-wide genotyping array 15783 2018-07-17 29423119 Khan S 2017-11-28 Oncotarget www.ncbi.nlm.nih.gov/pubmed/29423119 Meta-analysis of three genome-wide association studies identifies two loci that predict survival and treatment outcome in breast cancer. Survival in breast cancer (estrogen-receptor positive) 2,971 European ancestry individuals, 165 individuals NA Illumina [275827] (imputed) 2 event free survival time, estrogen-receptor positive breast cancer http://www.ebi.ac.uk/efo/EFO_0000482, http://www.ebi.ac.uk/efo/EFO_1000649 GCST005901 Genome-wide genotyping array 3136 2018-07-17 29423119 Khan S 2017-11-28 Oncotarget www.ncbi.nlm.nih.gov/pubmed/29423119 Meta-analysis of three genome-wide association studies identifies two loci that predict survival and treatment outcome in breast cancer. Survival in endocrine treated breast cancer (estrogen-receptor positive) 2,629 European ancestry individuals, 122 individuals NA Illumina [275827] (imputed) 1 event free survival time, estrogen-receptor positive breast cancer, response to endocrine therapy http://www.ebi.ac.uk/efo/EFO_0000482, http://www.ebi.ac.uk/efo/EFO_1000649, http://www.ebi.ac.uk/efo/EFO_0007613 GCST005900 Genome-wide genotyping array 2751 2018-03-16 29408531 Zhang D 2018-02-02 Gene www.ncbi.nlm.nih.gov/pubmed/29408531 The polymorphism rs671 at ALDH2 associated with serum uric acid levels in Chinese Han males: A genome-wide association study. Serum uric acid levels 1,634 Han Chinese ancestry individuals 2,818 Han Chinese ancestry individuals Illumina [532842] 2 uric acid measurement http://www.ebi.ac.uk/efo/EFO_0004761 GCST005369 Genome-wide genotyping array 1634 2017-10-05 28843344 Lv WQ 2017-08-23 J Mol Cell Cardiol www.ncbi.nlm.nih.gov/pubmed/28843344 Novel common variants associated with body mass index and coronary artery disease detected using a pleiotropic cFDR method. Coronary artery disease and/or body mass index (pleiotropy) 249,796 European ancestry individuals, 15,420 European and South Asian ancestry coronary artery disease cases, 15,062 European and South Asian controls 22,233 European ancestry cases, 64,762 European controls NR [NR] 0 body mass index, coronary artery disease http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0001645 GCST004838 Genome-wide genotyping array 280278 2017-10-23 28952330 Chen SP 2017-01-01 Cephalalgia www.ncbi.nlm.nih.gov/pubmed/28952330 Genome-wide association study identifies novel susceptibility loci for migraine in Han Chinese resided in Taiwan. Migraine without aura 1,005 Han Chinese ancestry cases, 1,053 Han Chinese ancestry controls 1,120 Han Chinese ancestry cases, 604 Han Chinese ancestry controls Affymetrix [590945] 2 migraine without aura http://www.ebi.ac.uk/efo/EFO_0005296 GCST004900 Genome-wide genotyping array 2058 2018-04-30 27777418 Wong ML 2016-10-25 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/27777418 The PHF21B gene is associated with major depression and modulates the stress response. Major depressive disorder 203 Mexican American cases, 196 Mexican American controls NA Illumina [83898] 17 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST005547 Exome genotyping array [Exome array] 399 2018-04-18 29432556 Brooke RJ 2018-02-08 J Natl Cancer Inst www.ncbi.nlm.nih.gov/pubmed/29432556 A High-risk Haplotype for Premature Menopause in Childhood Cancer Survivors Exposed to Gonadotoxic Therapy. Premature menopause in childhood cancer survivors 27 European ancestry cases, 3 African ancestry cases, 658 European ancestry controls, 111 African ancestry controls NA Affymetrix [10993255] (imputed) 8 primary ovarian insufficiency http://www.ebi.ac.uk/efo/EFO_0004266 GCST005518 Genome-wide genotyping array 799 2017-09-25 28839172 Mahlman M 2017-08-24 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28839172 Genome-wide association study of bronchopulmonary dysplasia: a potential role for variants near the CRP gene. Bronchopulmonary dysplasia in preterm infants 60 Finnish ancestry cases, 114 Finnish ancestry controls 234 European ancestry cases, 25 African ancestry cases, 633 European ancestry controls, 51 African ancestry controls Illumina [276306] (imputed) 0 Bronchopulmonary dysplasia http://www.orpha.net/ORDO/Orphanet_70589 GCST004783 Genome-wide genotyping array 174 2017-02-18 27193031 Marquez A 2016-05-18 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/27193031 A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus. Systemic lupus erythematosus or rheumatoid arthritis 2,237 European ancestry systemic lupus erythematosus cases, 3,911 European ancestry rheumatoid arthritis cases, 10,398 European ancestry controls 1,957 European ancestry systemic lupus erythematosus cases, 13,641 European ancestry rheumatoid arthritis cases, 36,509 European ancestry controls NR [at least 309839] (imputed) 9 rheumatoid arthritis, systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0002690 GCST003620 Genome-wide genotyping array 16546 2019-08-08 25861811 Li Z 2015-04-10 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/25861811 A common variant near TGFBR3 is associated with primary open angle glaucoma. Glaucoma (primary open-angle) 2,735 East Asian ancestry cases, 590 African American cases, 121 South Asian ancestry cases, 58 South East Asian ancestry cases, 6,410 East Asian ancestry controls, 636 African American controls, 716 South Asian ancestry controls, 1,984 South East Asian ancestry controls 4,773 European ancestry cases, 3,006 East Asian ancestry cases, 497 African American cases, 453 South Asian ancestry cases, 208 South East Asian ancestry cases, 236 Middle East ancestry cases, 11,786 European ancestry controls, 8,754 East Asian ancestry controls, 304 African American controls, 2,496 South Asian ancestry controls, 2,785 South East Asian ancestry controls, 655 Middle East ancestry controls Illumina [~ 272000] 4 open-angle glaucoma http://www.ebi.ac.uk/efo/EFO_0004190 GCST008391 Exome genotyping array [Exome array] 13250 2017-02-16 27203581 Sousa I 2016-05-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/27203581 Multicentric Genome-Wide Association Study for Primary Spontaneous Pneumothorax. Primary spontaneous pneumothorax 92 Portuguese ancestry cases, 129 Portuguese ancestry controls 100 Portuguese ancestry cases, 425 Portuguese ancestry controls Affymetrix [868260] 0 Spontaneous pneumothorax http://purl.obolibrary.org/obo/HP_0002108 GCST003618 Genome-wide genotyping array 221 2018-07-30 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Total cholesterol levels 128,305 Japanese ancestry individuals NA Illumina [6108953] (imputed) 45 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST006034 Genome-wide genotyping array 128305 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. White blood cell count 107,964 Japanese ancestry individuals NA Illumina [6108953] (imputed) 42 leukocyte count http://www.ebi.ac.uk/efo/EFO_0004308 GCST005973 Genome-wide genotyping array 107964 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Neutrophil count 62,076 Japanese ancestry individuals NA Illumina [6108953] (imputed) 22 neutrophil count http://www.ebi.ac.uk/efo/EFO_0004833 GCST005974 Genome-wide genotyping array 62076 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Eosinophil counts 62,076 Japanese ancestry individuals NA Illumina [6108953] (imputed) 20 eosinophil count http://www.ebi.ac.uk/efo/EFO_0004842 GCST005975 Genome-wide genotyping array 62076 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. White blood cell count (basophil) 62,076 Japanese ancestry individuals NA Illumina [6108953] (imputed) 28 basophil count http://www.ebi.ac.uk/efo/EFO_0005090 GCST005976 Genome-wide genotyping array 62076 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Monocyte count 62,076 Japanese ancestry individuals NA Illumina [6108953] (imputed) 34 monocyte count http://www.ebi.ac.uk/efo/EFO_0005091 GCST005977 Genome-wide genotyping array 62076 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Lymphocyte counts 62,076 Japanese ancestry individuals NA Illumina [6108953] (imputed) 14 lymphocyte count http://www.ebi.ac.uk/efo/EFO_0004587 GCST005997 Genome-wide genotyping array 62076 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Red blood cell count 108,794 Japanese ancestry individuals NA Illumina [6108953] (imputed) 60 erythrocyte count http://www.ebi.ac.uk/efo/EFO_0004305 GCST005996 Genome-wide genotyping array 108794 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Hemoglobin 108,769 Japanese ancestry individuals NA Illumina [6108953] (imputed) 20 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST005995 Genome-wide genotyping array 108769 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Hematocrit 108,757 Japanese ancestry individuals NA Illumina [6108953] (imputed) 23 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST005994 Genome-wide genotyping array 108757 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Mean corpuscular volume 108,256 Japanese ancestry individuals NA Illumina [6108953] (imputed) 111 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST006011 Genome-wide genotyping array 108256 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Mean corpuscular hemoglobin 108,054 Japanese ancestry individuals NA Illumina [6108953] (imputed) 96 mean corpuscular hemoglobin http://www.ebi.ac.uk/efo/EFO_0004527 GCST005993 Genome-wide genotyping array 108054 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Mean corpuscular hemoglobin concentration 108,728 Japanese ancestry individuals NA Illumina [6108953] (imputed) 44 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST005992 Genome-wide genotyping array 108728 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Platelet count 108,208 Japanese ancestry individuals NA Illumina [6108953] (imputed) 96 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST005991 Genome-wide genotyping array 108208 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Non-albumin protein levels 98,538 Japanese ancestry individuals NA Illumina [6108953] (imputed) 58 serum non-albumin protein measurement http://www.ebi.ac.uk/efo/EFO_0004568 GCST005990 Genome-wide genotyping array 98538 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Serum total protein level 113,509 Japanese ancestry individuals NA Illumina [6108953] (imputed) 39 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST005989 Genome-wide genotyping array 113509 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Serum albumin levels 102,223 Japanese ancestry individuals NA Illumina [6108953] (imputed) 17 serum albumin measurement http://www.ebi.ac.uk/efo/EFO_0004535 GCST005988 Genome-wide genotyping array 102223 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Albumin-globulin ratio 98,626 Japanese ancestry individuals NA Illumina [6108953] (imputed) 50 albumin:globulin ratio measurement http://www.ebi.ac.uk/efo/EFO_0005128 GCST005987 Genome-wide genotyping array 98626 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Blood urea nitrogen levels 139,818 Japanese ancestry individuals NA Illumina [6108953] (imputed) 44 blood urea nitrogen measurement http://www.ebi.ac.uk/efo/EFO_0004741 GCST005986 Genome-wide genotyping array 139818 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Creatinine levels 142,097 Japanese ancestry individuals NA Illumina [6108953] (imputed) 68 creatinine measurement http://www.ebi.ac.uk/efo/EFO_0004518 GCST005985 Genome-wide genotyping array 142097 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Glomerular filtration rate 143,658 Japanese ancestry individuals NA Illumina [6108953] (imputed) 72 glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0005208 GCST005984 Genome-wide genotyping array 143658 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Serum uric acid levels 109,029 Japanese ancestry individuals NA Illumina [6108953] (imputed) 48 uric acid measurement http://www.ebi.ac.uk/efo/EFO_0004761 GCST005983 Genome-wide genotyping array 109029 2018-07-30 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Sodium levels 127,304 Japanese ancestry individuals NA Illumina [6108953] (imputed) 14 sodium measurement http://www.ebi.ac.uk/efo/EFO_0009282 GCST006032 Genome-wide genotyping array 127304 2018-07-30 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Potassium levels 132,938 Japanese ancestry individuals NA Illumina [6108953] (imputed) 15 potassium measurement http://www.ebi.ac.uk/efo/EFO_0009283 GCST006031 Genome-wide genotyping array 132938 2018-07-30 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Chloride levels 126,402 Japanese ancestry individuals NA Illumina [6108953] (imputed) 19 chloride measurement http://www.ebi.ac.uk/efo/EFO_0009284 GCST006030 Genome-wide genotyping array 126402 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Serum alkaline phosphatase levels 105,030 Japanese ancestry individuals NA Illumina [6108953] (imputed) 48 alkaline phosphatase measurement http://www.ebi.ac.uk/efo/EFO_0004533 GCST006016 Genome-wide genotyping array 105030 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Gamma glutamyl transferase levels 118,309 Japanese ancestry individuals NA Illumina [6108953] (imputed) 50 serum gamma-glutamyl transferase measurement http://www.ebi.ac.uk/efo/EFO_0004532 GCST006019 Genome-wide genotyping array 118309 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Activated partial thromboplastin time 37,767 Japanese ancestry individuals NA Illumina [6108953] (imputed) 13 partial thromboplastin time http://www.ebi.ac.uk/efo/EFO_0004310 GCST006018 Genome-wide genotyping array 37767 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Prothrombin time 58,110 Japanese ancestry individuals NA Illumina [6108953] (imputed) 14 prothrombin time measurement http://www.ebi.ac.uk/efo/EFO_0008390 GCST006017 Genome-wide genotyping array 58110 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Fibrinogen levels 18,348 Japanese ancestry individuals NA Illumina [6108953] (imputed) 1 fibrinogen measurement http://www.ebi.ac.uk/efo/EFO_0004623 GCST006015 Genome-wide genotyping array 18348 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Creatine kinase levels 106,080 Japanese ancestry individuals NA Illumina [6108953] (imputed) 46 creatine kinase measurement http://www.ebi.ac.uk/efo/EFO_0004534 GCST006014 Genome-wide genotyping array 106080 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. Lactate dehydrogenase levels 126,319 Japanese ancestry individuals NA Illumina [6108953] (imputed) 14 L lactate dehydrogenase measurement http://www.ebi.ac.uk/efo/EFO_0004808 GCST006013 Genome-wide genotyping array 126319 2018-07-28 29403010 Kanai M 2018-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29403010 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. C-reactive protein levels 75,391 Japanese ancestry individuals NA Illumina [6108953] (imputed) 8 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST006012 Genome-wide genotyping array 75391 2017-03-16 27579533 Zhang M 2016-08-01 Oncotarget www.ncbi.nlm.nih.gov/pubmed/27579533 Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21. Pancreatic cancer 5,107 European ancestry cases, 8,845 European ancestry controls 6,076 cases, 7,555 controls Illumina [9132527] (imputed) 3 pancreatic carcinoma http://www.ebi.ac.uk/efo/EFO_0002618 GCST003758 Genome-wide genotyping array 13952 2018-02-14 29379196 Fadista J 2018-01-29 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29379196 Genome-wide association study of Hirschsprung disease detects a novel low-frequency variant at the RET locus. Hirschsprung disease 170 Danish ancestry cases, 4717 Danish ancestry controls 416 European ancestry cases, 903 European ancestry controls Illumina [6162479] (imputed) 7 Hirschsprung disease http://www.orpha.net/ORDO/Orphanet_388 GCST005289 Genome-wide genotyping array 4887 2017-02-24 27576016 Zhao B 2016-08-30 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/27576016 A Genome-Wide Association Study to Identify Single-Nucleotide Polymorphisms for Acute Kidney Injury. Acute kidney injury in critical illness 709 European ancestry cases, 619 European ancestry controls 206 European ancestry cases, 1,406 European ancestry controls Illumina [9076120] (imputed) 3 Acute kidney injury http://purl.obolibrary.org/obo/HP_0001919 GCST003656 Genome-wide genotyping array 1328 2018-09-20 29503163 Yu H 2018-03-01 Lancet Psychiatry www.ncbi.nlm.nih.gov/pubmed/29503163 Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study. Response to antipsychotic treatment in schizophrenia 2,413 Han Chinese ancestry cases 1,379 Han Chinese ancestry cases Illumina [6097251] (imputed) 10 response to antipsychotic drug http://purl.obolibrary.org/obo/GO_0097332 GCST006292 Genome-wide genotyping array 2413 2018-09-20 29503163 Yu H 2018-03-01 Lancet Psychiatry www.ncbi.nlm.nih.gov/pubmed/29503163 Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study. Response to haloperidol in schizophrenia 192 Han Chinese ancestry cases NA Illumina [6097251] (imputed) 6 response to haloperidol http://purl.obolibrary.org/obo/GO_1905119 GCST006298 Genome-wide genotyping array 192 2018-09-20 29503163 Yu H 2018-03-01 Lancet Psychiatry www.ncbi.nlm.nih.gov/pubmed/29503163 Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study. Response to perphenazine in schizophrenia 193 Han Chinese ancestry cases NA Illumina [6097251] (imputed) 5 response to perphenazine http://purl.obolibrary.org/obo/GO_0097334 GCST006297 Genome-wide genotyping array 193 2018-09-20 29503163 Yu H 2018-03-01 Lancet Psychiatry www.ncbi.nlm.nih.gov/pubmed/29503163 Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study. Response to ziprazidone in schizophrenia 408 Han Chinese ancestry cases NA Illumina [6097251] (imputed) 9 response to ziprasidone http://purl.obolibrary.org/obo/GO_0097337 GCST006296 Genome-wide genotyping array 408 2018-09-20 29503163 Yu H 2018-03-01 Lancet Psychiatry www.ncbi.nlm.nih.gov/pubmed/29503163 Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study. Response to quetiapine in schizophrenia 386 Han Chinese ancestry cases NA Illumina [6097251] (imputed) 15 response to quetiapine http://purl.obolibrary.org/obo/GO_0097335 GCST006295 Genome-wide genotyping array 386 2018-09-19 29503163 Yu H 2018-03-01 Lancet Psychiatry www.ncbi.nlm.nih.gov/pubmed/29503163 Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study. Response to aripiprazole in schizophrenia 397 Han Chinese ancestry cases 405 Han Chinese ancestry cases Illumina [6097251] (imputed) 2 response to aripiprazole, response to antipsychotic drug http://www.ebi.ac.uk/efo/EFO_0009261, http://purl.obolibrary.org/obo/GO_0097332 GCST006285 Genome-wide genotyping array 397 2018-09-20 29503163 Yu H 2018-03-01 Lancet Psychiatry www.ncbi.nlm.nih.gov/pubmed/29503163 Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study. Response to risperidone in schizophrenia 425 Han Chinese ancestry cases 559 Han Chinese ancestry cases Illumina [6097251] (imputed) 1 response to risperidone http://purl.obolibrary.org/obo/GO_0097336 GCST006294 Genome-wide genotyping array 425 2018-09-20 29503163 Yu H 2018-03-01 Lancet Psychiatry www.ncbi.nlm.nih.gov/pubmed/29503163 Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study. Response to olanzapine in schizophrenia 412 Han Chinese ancestry cases 415 Han Chinese ancestry cases Illumina [6097251] (imputed) 2 response to olanzapine http://purl.obolibrary.org/obo/GO_0097333 GCST006293 Genome-wide genotyping array 412 2018-03-23 29391396 McElroy SL 2018-02-02 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29391396 Bipolar disorder with binge eating behavior: a genome-wide association study implicates PRR5-ARHGAP8. Binge eating behaviour in bipolar disorder 398 European ancestry bipolar disorder cases, 1,231 European ancestry bipolar disorder controls NA Affymetrix, Illumina [8000000] (imputed) 5 binge eating http://www.ebi.ac.uk/efo/EFO_0005924 GCST005387 Genome-wide genotyping array 1629 2018-03-23 29391396 McElroy SL 2018-02-02 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29391396 Bipolar disorder with binge eating behavior: a genome-wide association study implicates PRR5-ARHGAP8. Binge eating behaviour and bipolar disorder 398 European ancestry cases, 1,811 European ancestry controls NA Affymetrix, Illumina [8000000] (imputed) 5 binge eating, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0005924, http://www.ebi.ac.uk/efo/EFO_0000289 GCST005386 Genome-wide genotyping array 2209 2018-08-30 29505938 Dunn EC 2017-12-16 J Psychiatr Res www.ncbi.nlm.nih.gov/pubmed/29505938 Genome-wide association study of depressive symptoms in the Hispanic Community Health Study/Study of Latinos. Depressive symptoms 12,310 Hispanic individuals 8,048 Hispanic individuals Illumina [2232944] (imputed) 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST006174 Genome-wide genotyping array 12310 2017-12-20 29170203 Alonso N 2017-11-23 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/29170203 Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density. Fractures (vertebral) 1,553 European ancestry cases, 4,340 European ancestry controls 694 European ancestry cases, 2,105 European ancestry controls, 334 cases, 1,657 controls Affymetrix, Illumina [2366456] (imputed) 3 spinal fracture http://www.ebi.ac.uk/efo/EFO_0003902 GCST005097 Genome-wide genotyping array 5893 2018-01-10 29145611 Hu Y 2017-11-14 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/29145611 Identification of Novel Potentially Pleiotropic Variants Associated With Osteoporosis and Obesity Using the cFDR Method. Osteoporosis or obesity (pleiotropy) 53,236 European ancestry individuals (femoral neck BMI), 322,154 European ancestry individuals (BMI), 17,070 individuals (BMI), 210,088 European ancestry individuals (WHR), 14,371 individuals (WHR) NA NR [> 2000000] 0 obesity, osteoporosis http://www.ebi.ac.uk/efo/EFO_0001073, http://www.ebi.ac.uk/efo/EFO_0003882 GCST005114 Genome-wide genotyping array 616919 2016-12-21 27167565 Stein MB 2016-05-11 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/27167565 Genome-wide Association Studies of Posttraumatic Stress Disorder in 2 Cohorts of US Army Soldiers. Post-traumatic stress disorder 2140 European ancestry cases, 497 African American ancestry cases, 530 Latino American ancestry cases, 2909 European ancestry trauma-exposed controls, 815 African American ancestry trauma-exposed controls, 883 Latino American ancestry trauma-exposed controls. 672 European ancestry cases, 97 African American ancestry cases, 178 Latino American ancestry cases, 3335 European ancestry trauma-exposed controls, 570 African American ancestry trauma-exposed controls, 1064 Latino American ancestry trauma-exposed controls. Illumina [664457] (imputed) 1 post-traumatic stress disorder http://www.ebi.ac.uk/efo/EFO_0001358 GCST003495 Genome-wide genotyping array 7774 2016-07-15 27186693 Aydin-Son Y 2015-07-01 Turk J Pediatr www.ncbi.nlm.nih.gov/pubmed/27186693 Systems-level analysis of genome wide association study results for a pilot juvenile idiopathic arthritis family study. Arthritis (juvenile idiopathic) 13 Caucasian Eastern Mediterranean ancestry oligoarticular case-parent trios, 13 Caucasian Eastern Mediterranean ancestry rheumatoid factor negative polyarticular case-parent trios NA Affymetrix [249676] 0 juvenile idiopathic arthritis http://www.ebi.ac.uk/efo/EFO_0002609 GCST003011 Genome-wide genotyping array 26 2016-11-30 27206850 Wang M 2016-03-29 Cancer Res www.ncbi.nlm.nih.gov/pubmed/27206850 Genome-Wide Association Study of Bladder Cancer in a Chinese Cohort Reveals a New Susceptibility Locus at 5q12.3. Bladder cancer 578 Han Chinese ancestry cases, 1,006 Han Chinese ancestry controls 2,828 Han Chinese ancestry cases, 3,639 Han Chinese ancestry controls Illumina [478403] (imputed) 1 bladder carcinoma http://www.ebi.ac.uk/efo/EFO_0000292 GCST003384 Genome-wide genotyping array 1584 2017-03-28 27723809 Matsunami K 2016-10-10 PLoS One www.ncbi.nlm.nih.gov/pubmed/27723809 Genome-Wide Association Study Identifies ZNF354C Variants Associated with Depression from Interferon-Based Therapy for Chronic Hepatitis C. Depression in response to interferon-based therapy in chronic hepatitis C 45 Japanese ancestry cases, 179 Japanese ancestry controls 40 Japanese ancestry cases, 120 Japanese ancestry controls Affymetrix [at least 551176] (imputed) 4 response to interferon, depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007859, http://www.ebi.ac.uk/efo/EFO_0007006 GCST003824 Genome-wide genotyping array 224 2017-02-19 27195777 Sano M 2016-05-19 PLoS One www.ncbi.nlm.nih.gov/pubmed/27195777 Genome-Wide Association Study of Absolute QRS Voltage Identifies Common Variants of TBX3 as Genetic Determinants of Left Ventricular Mass in a Healthy Japanese Population. Left ventricular QRS voltage 2,994 Japanese ancestry individuals 2,941 Japanese ancestry individuals Illumina [~ 2500000] 2 QRS amplitude, S wave amplitude, R wave amplitude http://www.ebi.ac.uk/efo/EFO_0007742, http://www.ebi.ac.uk/efo/EFO_0007740, http://www.ebi.ac.uk/efo/EFO_0007741 GCST003630 Genome-wide genotyping array 2994 2017-01-12 27153935 Zhang CE 2016-05-06 J Dermatol www.ncbi.nlm.nih.gov/pubmed/27153935 Variation at HLA-DPB1 is associated with dermatomyositis in Chinese population. Dermatomyositis 127 Han Chinese ancestry case, 1,566 Han Chinese ancestry controls NA Illumina [812602] 4 dermatomyositis http://www.ebi.ac.uk/efo/EFO_0000398 GCST003522 Genome-wide genotyping array 1693 2017-02-20 27244217 Fogh I 2016-05-31 JAMA Neurol www.ncbi.nlm.nih.gov/pubmed/27244217 Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis. Survival in sporadic amyotrophic lateral sclerosis 4,256 European ancestry cases NA Illumina [7174392] (imputed) 6 sporadic amyotrophic lateral sclerosis, survival time http://www.ebi.ac.uk/efo/EFO_0001357, http://www.ebi.ac.uk/efo/EFO_0000714 GCST003632 Genome-wide genotyping array 4256 2018-04-26 25751624 Onengut-Gumuscu S 2015-04-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/25751624 Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers. Type 1 diabetes 6,683 European ancestry cases, 12,173 European ancestry controls, 2,601 European ancestry affected sibling pair families, 69 European ancestry trios NA Illumina [135870] 51 type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001359 GCST005536 Targeted genotyping array [ImmunoChip] 21526 2017-02-24 27424798 Chahal HS 2016-07-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/27424798 Genome-wide association study identifies novel susceptibility loci for cutaneous squamous cell carcinoma. Cutaneous squamous cell carcinoma 6,579 European ancestry cases, 280,558 European ancestry controls 825 European ancestry cases, 11,518 European ancestry controls Affymetrix, Illumina [at least 560000] (imputed) 13 cutaneous squamous cell carcinoma http://www.ebi.ac.uk/efo/EFO_1001927 GCST003655 Genome-wide genotyping array 287137 2017-03-10 27412988 Tise CG 2016-07-13 G3 (Bethesda) www.ncbi.nlm.nih.gov/pubmed/27412988 From Genotype to Phenotype: Nonsense Variants in SLC13A1 Are Associated with Decreased Serum Sulfate and Increased Serum Aminotransferases. Serum sulfate level 917 Old Order Amish (founder/genetic isolate) individuals NA Affymetrix [NR] 6 sulfate measurement http://www.ebi.ac.uk/efo/EFO_0007864 GCST003723 Genome-wide genotyping array 917 2019-04-15 29045471 Robiou-du-Pont S 2017-10-18 PLoS One www.ncbi.nlm.nih.gov/pubmed/29045471 Parental and offspring contribution of genetic markers of adult blood pressure in early life: The FAMILY study. Blood pressure (parental or offspring effect) 515 children, 406 mothers and 237 fathers NA Illumina [up to 196725] 0 blood pressure change measurement http://www.ebi.ac.uk/efo/EFO_0006943 GCST007577 Targeted genotyping array [Cardio-MetaboChip] 1158 2017-12-05 28724990 Zillikens MC 2017-07-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28724990 Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. Appendicular lean mass 27,488 European ancestry individuals, 842 Old Order Amish individuals 42,360 European ancestry individuals, 380 African American individuals, 2,350 Korean ancestry individuals Affymetrix, Illumina [at least 1912063] (imputed) 5 appendicular lean mass http://www.ebi.ac.uk/efo/EFO_0004980 GCST005037 Genome-wide genotyping array 28330 2017-12-05 28724990 Zillikens MC 2017-07-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28724990 Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. Lean body mass 37,450 European ancestry individuals, 842 Old Order Amish individuals 47,227 European ancestry individuals, 380 African American individuals, 8,034 Korean ancestry individuals, 7,834 Indian ancestry individuals Affymetrix, Illumina [at least 1912063] (imputed) 7 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST005036 Genome-wide genotyping array 38292 2017-08-09 28540843 Mbarek H 2017-05-25 Twin Res Hum Genet www.ncbi.nlm.nih.gov/pubmed/28540843 Genome-Wide Significance for PCLO as a Gene for Major Depressive Disorder. Major depressive disorder 1,942 European ancestry cases, 4,565 European ancestry controls NA Affymetrix [NR] (imputed) 1 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST004486 Genome-wide genotyping array 6507 2018-08-13 27898682 Lotta LA 2016-11-29 PLoS Med www.ncbi.nlm.nih.gov/pubmed/27898682 Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis. Branched-chain amino acid levels (Isoleucine) 16,596 European ancestry individuals NA Affymetrix, Illumina [10500000] (imputed) 5 amino acid measurement http://www.ebi.ac.uk/efo/EFO_0005134 GCST006077 Genome-wide genotyping array 16596 2018-08-13 27898682 Lotta LA 2016-11-29 PLoS Med www.ncbi.nlm.nih.gov/pubmed/27898682 Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis. Branched-chain amino acid levels (Leucine) 16,596 European ancestry individuals NA Affymetrix, Illumina [10500000] (imputed) 2 amino acid measurement http://www.ebi.ac.uk/efo/EFO_0005134 GCST006076 Genome-wide genotyping array 16596 2018-08-13 27898682 Lotta LA 2016-11-29 PLoS Med www.ncbi.nlm.nih.gov/pubmed/27898682 Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis. Branched-chain amino acid levels (Valine) 16,596 European ancestry individuals NA Affymetrix, Illumina [10500000] (imputed) 3 amino acid measurement http://www.ebi.ac.uk/efo/EFO_0005134 GCST006078 Genome-wide genotyping array 16596 2018-01-24 27455349 Minster RL 2016-07-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27455349 A thrifty variant in CREBRF strongly influences body mass index in Samoans. Body mass index 3,072 Samoan (founder/genetic isolate) individuals 2,102 Samoan (founder/genetic isolate) individuals Affymetrix [659492] 1 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST005181 Genome-wide genotyping array 3072 2018-08-16 27668658 Iotchkova V 2016-11-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27668658 Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps. Cardiometabolic and hematological traits up to 35,981 European ancestry individuals up to 102,505 European ancestry individuals Affymetrix, Illumina [17000000] (imputed) 17 hematological measurement http://www.ebi.ac.uk/efo/EFO_0004503 GCST006101 Genome-wide genotyping array 35981 2018-02-02 29313844 Willems SM 2017-07-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29313844 Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness. Hand grip strength 142,035 European ancestry individuals 53,145 European ancestry individuals Affymetrix [at least 17000000] (imputed) 19 grip strength measurement http://www.ebi.ac.uk/efo/EFO_0006941 GCST005235 Genome-wide genotyping array 142035 2018-02-02 29313844 Willems SM 2017-07-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29313844 Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness. Fat mass index 12,851 individuals NA Affymetrix [NR] (imputed) 0 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST005233 Genome-wide genotyping array 12851 2018-02-02 29313844 Willems SM 2017-07-12 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29313844 Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness. Lean mass index 12,851 individuals NA Affymetrix [at least 17000000] (imputed) 0 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST005234 Genome-wide genotyping array 12851 2016-09-20 26482880 Buch S 2015-10-19 Nat Genet www.ncbi.nlm.nih.gov/pubmed/26482880 A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis. Cirrhosis (alcohol related) 712 European ancestry cases, 1,426 European ancestry alchocol dependent controls 1,148 European ancestry cases, 922 European ancestry alchocol dependent controls Illumina [6770425] (imputed) 3 alcoholic liver cirrhosis http://www.ebi.ac.uk/efo/EFO_1000802 GCST003153 Genome-wide genotyping array 2138 2016-09-28 26460308 Ghesquieres H 2015-10-12 J Clin Oncol www.ncbi.nlm.nih.gov/pubmed/26460308 Genome-Wide Association Study of Event-Free Survival in Diffuse Large B-Cell Lymphoma Treated With Immunochemotherapy. Event free survival in diffuse large B-cell lymphoma treated with immunochemotherapy 852 European ancestry cases 685 European ancestry cases Illumina [> 552942] (imputed) 2 diffuse large B-cell lymphoma, event free survival time, response to immunochemotherapy http://www.ebi.ac.uk/efo/EFO_0000403, http://www.ebi.ac.uk/efo/EFO_0000482, http://www.ebi.ac.uk/efo/EFO_0007754 GCST003178 Genome-wide genotyping array 852 2017-11-30 29059683 Michailidou K 2017-10-23 Nature www.ncbi.nlm.nih.gov/pubmed/29059683 Association analysis identifies 65 new breast cancer risk loci. Breast cancer 76,192 European ancestry cases, 63,082 European ancestry controls 46,785 European ancestry cases, 42,892 European ancestry controls, 14,068 East Asian ancestry cases, 13,104 East Asian ancestry controls Illumina [~ 11800000] (imputed) 803 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST004988 Genome-wide genotyping array 139274 2017-08-11 28545128 McDaniel LD 2017-05-18 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28545128 Common variants upstream of MLF1 at 3q25 and within CPZ at 4p16 associated with neuroblastoma. Sporadic neuroblastoma 2,101 European ancestry child cases, 4,202 European ancestry controls 365 African American child cases, 2,491 African American controls, 427 European ancestry cases, 783 European ancestry controls, 371 cases, 1,122 controls Illumina [7968453] (imputed) 9 neuroblastoma http://www.ebi.ac.uk/efo/EFO_0000621 GCST004510 Genome-wide genotyping array 6303 2018-01-24 29206233 Shendre A 2017-12-04 PLoS One www.ncbi.nlm.nih.gov/pubmed/29206233 Genome-wide admixture and association study of subclinical atherosclerosis in the Women's Interagency HIV Study (WIHS). Common carotid intima-media thickness in HIV negative individuals 288 Black non-Hispanic HIV-negative women NA Illumina [1124301] 13 common carotid intimal medial thickness http://www.ebi.ac.uk/efo/EFO_0004860 GCST005182 Genome-wide genotyping array 288 2018-01-24 29206233 Shendre A 2017-12-04 PLoS One www.ncbi.nlm.nih.gov/pubmed/29206233 Genome-wide admixture and association study of subclinical atherosclerosis in the Women's Interagency HIV Study (WIHS). Common carotid intima-media thickness in HIV infection 682 Black non-Hispanic HIV-positive women NA Illumina [1124301] 12 common carotid intimal medial thickness http://www.ebi.ac.uk/efo/EFO_0004860 GCST005184 Genome-wide genotyping array 682 2018-01-24 29206233 Shendre A 2017-12-04 PLoS One www.ncbi.nlm.nih.gov/pubmed/29206233 Genome-wide admixture and association study of subclinical atherosclerosis in the Women's Interagency HIV Study (WIHS). Common carotid intima-media thickness 682 Black non-Hispanic HIV-positive women, 288 Black non-Hispanic HIV-negative women NA Illumina [1124301] 10 common carotid intimal medial thickness http://www.ebi.ac.uk/efo/EFO_0004860 GCST005183 Genome-wide genotyping array 970 2018-01-26 29271184 Chung GE 2017-12-26 Gut Liver www.ncbi.nlm.nih.gov/pubmed/29271184 Genetic Polymorphisms of PNPLA3 and SAMM50 Are Associated with Nonalcoholic Fatty Liver Disease in a Korean Population. Nonalcoholic fatty liver disease 1,593 East Asian ancestry cases, 2,816 East Asian ancestry controls 744 East Asian ancestry cases, 1,137 East Asian ancestry controls Affymetrix [584061] 2 non-alcoholic fatty liver disease http://www.ebi.ac.uk/efo/EFO_0003095 GCST005190 Genome-wide genotyping array 4409 2018-01-19 29253144 Voigt EA 2017-12-14 J Infect Dis www.ncbi.nlm.nih.gov/pubmed/29253144 Polymorphisms in the Wilms Tumor Gene Are Associated With Interindividual Variations in Rubella Virus-Specific Cellular Immunity After Measles-Mumps-Rubella II Vaccination. Rubella-specific interferon-gamma secretion 1,643 European ancestry individuals, 202 African American individuals NA Illumina [NR] (imputed) 0 interferon gamma measurement, response to vaccine http://www.ebi.ac.uk/efo/EFO_0008165, http://www.ebi.ac.uk/efo/EFO_0004645 GCST005177 Genome-wide genotyping array 1845 2018-01-19 29253144 Voigt EA 2017-12-14 J Infect Dis www.ncbi.nlm.nih.gov/pubmed/29253144 Polymorphisms in the Wilms Tumor Gene Are Associated With Interindividual Variations in Rubella Virus-Specific Cellular Immunity After Measles-Mumps-Rubella II Vaccination. Rubella-specific interleukin-6 secretion 1,643 European ancestry individuals, 202 African American individuals NA Illumina [NR] (imputed) 1 interleukin-6 measurement, response to vaccine http://www.ebi.ac.uk/efo/EFO_0004810, http://www.ebi.ac.uk/efo/EFO_0004645 GCST005176 Genome-wide genotyping array 1845 2017-09-28 28679651 Meziane I 2017-07-04 Haematologica www.ncbi.nlm.nih.gov/pubmed/28679651 Genome-wide association study of clinical parameters in immunoglobulin light chain amyloidosis in three patient cohorts. Immunoglobulin light chain (AL) amyloidosis (serum Ig light chain only lambda based profile) 404 cases, controls NA NR [NR] 1 AL amyloidosis, IgG isotype profile measurement http://www.orpha.net/ORDO/Orphanet_85443, http://www.ebi.ac.uk/efo/EFO_0008366 GCST004804 Genome-wide genotyping array 404 2017-09-28 28679651 Meziane I 2017-07-04 Haematologica www.ncbi.nlm.nih.gov/pubmed/28679651 Genome-wide association study of clinical parameters in immunoglobulin light chain amyloidosis in three patient cohorts. Immunoglobulin light chain (AL) amyloidosis (liver involvement) 194 cases, controls NA NR [NR] 1 AL amyloidosis, liver amyloid deposition measurement http://www.orpha.net/ORDO/Orphanet_85443, http://www.ebi.ac.uk/efo/EFO_0008374 GCST004807 Genome-wide genotyping array 194 2017-09-28 28679651 Meziane I 2017-07-04 Haematologica www.ncbi.nlm.nih.gov/pubmed/28679651 Genome-wide association study of clinical parameters in immunoglobulin light chain amyloidosis in three patient cohorts. Immunoglobulin light chain (AL) amyloidosis (heart and kidney involvement) 426 cases, controls NA NR [NR] 1 heart amyloid deposition measurement, AL amyloidosis, kidney amyloid deposition measurement http://www.ebi.ac.uk/efo/EFO_0008365, http://www.orpha.net/ORDO/Orphanet_85443, http://www.ebi.ac.uk/efo/EFO_0008371 GCST004806 Genome-wide genotyping array 426 2017-09-28 28679651 Meziane I 2017-07-04 Haematologica www.ncbi.nlm.nih.gov/pubmed/28679651 Genome-wide association study of clinical parameters in immunoglobulin light chain amyloidosis in three patient cohorts. Immunoglobulin light (AL) amyloidosis (serum Ig kappa profile) 85 cases, controls NA NR [NR] 0 AL amyloidosis, IgG isotype profile measurement http://www.orpha.net/ORDO/Orphanet_85443, http://www.ebi.ac.uk/efo/EFO_0008366 GCST004810 Genome-wide genotyping array 85 2017-09-28 28679651 Meziane I 2017-07-04 Haematologica www.ncbi.nlm.nih.gov/pubmed/28679651 Genome-wide association study of clinical parameters in immunoglobulin light chain amyloidosis in three patient cohorts. Immunoglobulin light chain (AL) amyloidosis (serum Ig light chain only lambda/kappa based profile) 535 cases, controls NA NR [NR] 1 AL amyloidosis, IgG isotype profile measurement http://www.orpha.net/ORDO/Orphanet_85443, http://www.ebi.ac.uk/efo/EFO_0008366 GCST004811 Genome-wide genotyping array 535 2017-09-28 28679651 Meziane I 2017-07-04 Haematologica www.ncbi.nlm.nih.gov/pubmed/28679651 Genome-wide association study of clinical parameters in immunoglobulin light chain amyloidosis in three patient cohorts. Immunoglobulin light chain (AL) amyloidosis (serum Ig lambda profile) 345 cases, controls NA NR [NR] 2 AL amyloidosis, IgG isotype profile measurement http://www.orpha.net/ORDO/Orphanet_85443, http://www.ebi.ac.uk/efo/EFO_0008366 GCST004809 Genome-wide genotyping array 345 2017-09-28 28679651 Meziane I 2017-07-04 Haematologica www.ncbi.nlm.nih.gov/pubmed/28679651 Genome-wide association study of clinical parameters in immunoglobulin light chain amyloidosis in three patient cohorts. Immunoglobulin light chain (AL) amyloidosis (heart involvement) 835 cases, controls NA NR [NR] 1 heart amyloid deposition measurement, AL amyloidosis http://www.ebi.ac.uk/efo/EFO_0008365, http://www.orpha.net/ORDO/Orphanet_85443 GCST004805 Genome-wide genotyping array 835 2017-09-28 28679651 Meziane I 2017-07-04 Haematologica www.ncbi.nlm.nih.gov/pubmed/28679651 Genome-wide association study of clinical parameters in immunoglobulin light chain amyloidosis in three patient cohorts. Immunoglobulin light chain (AL) amyloidosis (kidney involvement) 844 cases, controls NA NR [NR] 1 AL amyloidosis, kidney amyloid deposition measurement http://www.orpha.net/ORDO/Orphanet_85443, http://www.ebi.ac.uk/efo/EFO_0008371 GCST004812 Genome-wide genotyping array 844 2017-09-28 28679651 Meziane I 2017-07-04 Haematologica www.ncbi.nlm.nih.gov/pubmed/28679651 Genome-wide association study of clinical parameters in immunoglobulin light chain amyloidosis in three patient cohorts. Immunoglobulin light chain (AL) amyloidosis (serum IgG profile) 447 cases, controls NA NR [NR] 1 AL amyloidosis, IgG isotype profile measurement http://www.orpha.net/ORDO/Orphanet_85443, http://www.ebi.ac.uk/efo/EFO_0008366 GCST004808 Genome-wide genotyping array 447 2017-10-08 28886140 Kwon YC 2017-09-08 PLoS One www.ncbi.nlm.nih.gov/pubmed/28886140 Male-specific association of the FCGR2A His167Arg polymorphism with Kawasaki disease. Kawasaki disease 165 East Asian ancestry male cases, 84 East Asian ancestry female cases, 783 East Asian ancestry male controls, 217 East Asian ancestry female controls 705 East Asian ancestry male cases, 507 East Asian ancestry female cases, 1,484 East Asian ancestry male controls, 2,818 East Asian ancestry female controls, 64 male cases, 36 female cases, 180 male controls, 67 male controls Illumina [NR] 1 mucocutaneous lymph node syndrome http://www.ebi.ac.uk/efo/EFO_0004246 GCST004859 Genome-wide genotyping array 1249 2018-12-17 25972531 Carter TC 2015-05-13 J Nutr www.ncbi.nlm.nih.gov/pubmed/25972531 Common Variants at Putative Regulatory Sites of the Tissue Nonspecific Alkaline Phosphatase Gene Influence Circulating Pyridoxal 5'-Phosphate Concentration in Healthy Adults. Pyridoxal levels 2,158 Irish ancestry individuals NA NR [757337] 0 vitamin B6 measurement http://www.ebi.ac.uk/efo/EFO_0004621 GCST006797 Genome-wide genotyping array 2158 2018-12-17 25972531 Carter TC 2015-05-13 J Nutr www.ncbi.nlm.nih.gov/pubmed/25972531 Common Variants at Putative Regulatory Sites of the Tissue Nonspecific Alkaline Phosphatase Gene Influence Circulating Pyridoxal 5'-Phosphate Concentration in Healthy Adults. 4-pyridoxic acid levels 2,158 Irish ancestry individuals NA NR [757337] 0 vitamin B6 measurement http://www.ebi.ac.uk/efo/EFO_0004621 GCST006798 Genome-wide genotyping array 2158 2018-12-17 25972531 Carter TC 2015-05-13 J Nutr www.ncbi.nlm.nih.gov/pubmed/25972531 Common Variants at Putative Regulatory Sites of the Tissue Nonspecific Alkaline Phosphatase Gene Influence Circulating Pyridoxal 5'-Phosphate Concentration in Healthy Adults. Pyridoxal 5'-phosphate levels 2,158 Irish ancestry individuals NA NR [757337] 1 vitamin B6 measurement http://www.ebi.ac.uk/efo/EFO_0004621 GCST006799 Genome-wide genotyping array 2158 2018-12-17 26961502 Wood AR 2016-03-10 Diabetologia www.ncbi.nlm.nih.gov/pubmed/26961502 Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively. Body mass index 29,925 British ancestry cases, 89,763 British ancestry controls NA NR [9288881] (imputed) 36 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST006802 Genome-wide genotyping array 119688 2018-12-17 26961502 Wood AR 2016-03-10 Diabetologia www.ncbi.nlm.nih.gov/pubmed/26961502 Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively. Type 2 diabetes 4,040 British ancestry cases, 113,735 British ancestry controls NA NR [9288881] (imputed) 13 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST006801 Genome-wide genotyping array 117775 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Oxygen saturation of hemoglobin levels 921 Tibetan ancestry individuals NA Illumina [3507568] (imputed) 0 oxygen saturation measurement http://www.ebi.ac.uk/efo/EFO_0005682 GCST006745 Genome-wide genotyping array 921 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Pulse rate 921 Tibetan ancestry individuals NA Illumina [3508046] (imputed) 0 resting heart rate http://www.ebi.ac.uk/efo/EFO_0004351 GCST006746 Genome-wide genotyping array 921 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Oxygenated hemoglobin levels 920 Tibetan ancestry individuals NA Illumina [3507568] (imputed) 1 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST006747 Genome-wide genotyping array 920 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Deoxygenated hemoglobin levels 921 Tibetan ancestry individuals NA Illumina [3507568] (imputed) 0 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST006748 Genome-wide genotyping array 921 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Child death (Number of children surviving at 1 year but died <5 years) 849 Tibetan ancestry individuals NA Illumina [3507585] (imputed) 0 offspring mortality measurement http://www.ebi.ac.uk/efo/EFO_0009437 GCST006749 Genome-wide genotyping array 849 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Child death in continuous marriage (Number of children surviving at 1 year but died <5 years) 593 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 offspring mortality measurement http://www.ebi.ac.uk/efo/EFO_0009437 GCST006750 Genome-wide genotyping array 593 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Child survival (Number of children surviving at 5 years) 849 Tibetan ancestry individuals NA Illumina [3507585] (imputed) 0 offspring survival measurement http://www.ebi.ac.uk/efo/EFO_0009436 GCST006751 Genome-wide genotyping array 849 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Child survival in continuous marriage (Number of children surviving at 5 years) 593 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 offspring survival measurement http://www.ebi.ac.uk/efo/EFO_0009436 GCST006752 Genome-wide genotyping array 593 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Child death (Proportion of children surviving at 1 year but died <5 years) 849 Tibetan ancestry individuals NA Illumina [3507585] (imputed) 0 offspring mortality measurement http://www.ebi.ac.uk/efo/EFO_0009437 GCST006753 Genome-wide genotyping array 849 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Child death in continuous marriage (Proportion of children surviving at 1 year but died <5 years) 593 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 offspring mortality measurement http://www.ebi.ac.uk/efo/EFO_0009437 GCST006754 Genome-wide genotyping array 593 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Child survival (Proportion of children surviving at 5 years) 849 Tibetan ancestry individuals NA Illumina [3507585] (imputed) 0 offspring survival measurement http://www.ebi.ac.uk/efo/EFO_0009436 GCST006755 Genome-wide genotyping array 849 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Child survival in continuous marriage (Proportion of children surviving at 5 years) 593 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 offspring survival measurement http://www.ebi.ac.uk/efo/EFO_0009436 GCST006756 Genome-wide genotyping array 593 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Juvenile death (Number of children surviving at 5 years but died <15 years) 531 Tibetan ancestry individuals NA Illumina [3506695] (imputed) 0 offspring mortality measurement http://www.ebi.ac.uk/efo/EFO_0009437 GCST006757 Genome-wide genotyping array 531 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Juvenile death in continuous marriage (Number of children surviving at 5 years but died <15 years) up to 531 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 offspring mortality measurement http://www.ebi.ac.uk/efo/EFO_0009437 GCST006758 Genome-wide genotyping array 531 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Juvenile death (Proportion of children surviving at 5 years but died <15 years) 531 Tibetan ancestry individuals NA Illumina [3507249] (imputed) 0 offspring mortality measurement http://www.ebi.ac.uk/efo/EFO_0009437 GCST006759 Genome-wide genotyping array 531 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Juvenile death in continuous marriage (Proportion of children surviving at 5 years but died <15 years) up to 531 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 offspring mortality measurement http://www.ebi.ac.uk/efo/EFO_0009437 GCST006760 Genome-wide genotyping array 531 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Juvenile survival (Number of children surviving at 15 years) 531 Tibetan ancestry individuals NA Illumina [3506695] (imputed) 0 offspring survival measurement http://www.ebi.ac.uk/efo/EFO_0009436 GCST006761 Genome-wide genotyping array 531 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Juvenile survival in continuous marriage (Number of children surviving at 15 years) up to 531 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 offspring survival measurement http://www.ebi.ac.uk/efo/EFO_0009436 GCST006762 Genome-wide genotyping array 531 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Juvenile survival (Proportion of children surviving at 15 years) 531 Tibetan ancestry individuals NA Illumina [3507249] (imputed) 0 offspring survival measurement http://www.ebi.ac.uk/efo/EFO_0009436 GCST006763 Genome-wide genotyping array 531 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Juvenile survival in continuous marriage (Proportion of children surviving at 15 years) up to 531 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 offspring survival measurement http://www.ebi.ac.uk/efo/EFO_0009436 GCST006764 Genome-wide genotyping array 531 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Number of live births 981 Tibetan ancestry individuals NA Illumina [3507697] (imputed) 1 fertility measurement http://www.ebi.ac.uk/efo/EFO_0006923 GCST006765 Genome-wide genotyping array 981 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Number of live births in continuous marriage 593 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 fertility measurement http://www.ebi.ac.uk/efo/EFO_0006923 GCST006766 Genome-wide genotyping array 593 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Proportion of live births 981 Tibetan ancestry individuals NA Illumina [3507697] (imputed) 0 fertility measurement http://www.ebi.ac.uk/efo/EFO_0006923 GCST006767 Genome-wide genotyping array 981 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Proportion of live births in continuous marriage 593 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 fertility measurement http://www.ebi.ac.uk/efo/EFO_0006923 GCST006768 Genome-wide genotyping array 593 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Number of pregnancies 981 Tibetan ancestry individuals NA Illumina [3507697] (imputed) 1 number of pregnancies measurement http://www.ebi.ac.uk/efo/EFO_0009438 GCST006771 Genome-wide genotyping array 981 2019-01-08 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Infant death in continuous marriage (Proportion of children died <1 year) 593 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 offspring mortality measurement http://www.ebi.ac.uk/efo/EFO_0009437 GCST006859 Genome-wide genotyping array 593 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Hemoglobin levels 921 Tibetan ancestry individuals NA Illumina [3507568] (imputed) 1 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST006720 Genome-wide genotyping array 921 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Infant and Child death (Number of children died <5 years) 849 Tibetan ancestry individuals NA Illumina [3507585] (imputed) 0 offspring mortality measurement http://www.ebi.ac.uk/efo/EFO_0009437 GCST006721 Genome-wide genotyping array 849 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Infant and Child death in continuous marriage (Number of children died <5 years) 593 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 offspring mortality measurement http://www.ebi.ac.uk/efo/EFO_0009437 GCST006722 Genome-wide genotyping array 593 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Infant and Child death (Proportion of children died <5 years) 849 Tibetan ancestry individuals NA Illumina [3507585] (imputed) 0 offspring mortality measurement http://www.ebi.ac.uk/efo/EFO_0009437 GCST006723 Genome-wide genotyping array 849 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Infant and Child death in continuous marriage (Proportion of children died <5 years) 593 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 offspring mortality measurement http://www.ebi.ac.uk/efo/EFO_0009437 GCST006724 Genome-wide genotyping array 593 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Infant, child and juvenile death (number of children died <15 years) 532 Tibetan ancestry individuals NA Illumina [3506123] (imputed) 0 offspring mortality measurement http://www.ebi.ac.uk/efo/EFO_0009437 GCST006725 Genome-wide genotyping array 532 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Infant, child and juvenile death in continuous marriage (number of children died <15 years) up to 532 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 offspring mortality measurement http://www.ebi.ac.uk/efo/EFO_0009437 GCST006726 Genome-wide genotyping array 532 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Infant, child and juvenile death (proportion of children died <15 years) 532 Tibetan ancestry individuals NA Illumina [3506123] (imputed) 1 offspring mortality measurement http://www.ebi.ac.uk/efo/EFO_0009437 GCST006727 Genome-wide genotyping array 532 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Infant, child and juvenile death in continuous marriage (proportion of children died <15 years) up to 532 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 1 offspring mortality measurement http://www.ebi.ac.uk/efo/EFO_0009437 GCST006730 Genome-wide genotyping array 532 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Infant death (Number of children died <1 year) 923 Tibetan ancestry individuals NA Illumina [3507108] (imputed) 0 offspring mortality measurement http://www.ebi.ac.uk/efo/EFO_0009437 GCST006728 Genome-wide genotyping array 923 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Infant death in continuous marriage (Number of children died <1 year) 593 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 offspring mortality measurement http://www.ebi.ac.uk/efo/EFO_0009437 GCST006729 Genome-wide genotyping array 593 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Infant death (Proportion of children died <1 year) 923 Tibetan ancestry individuals NA Illumina [3507108] (imputed) 0 offspring mortality measurement http://www.ebi.ac.uk/efo/EFO_0009437 GCST006731 Genome-wide genotyping array 923 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Infant survival (Number of children surviving at 1 year) 923 Tibetan ancestry individuals NA Illumina [3507108] (imputed) 0 offspring survival measurement http://www.ebi.ac.uk/efo/EFO_0009436 GCST006733 Genome-wide genotyping array 923 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Infant survival in continuous marriage (Number of children surviving at 1 year) 593 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 offspring survival measurement http://www.ebi.ac.uk/efo/EFO_0009436 GCST006734 Genome-wide genotyping array 593 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Infant survival (Proportion of children surviving at 1 year) 923 Tibetan ancestry individuals NA Illumina [3507108] (imputed) 0 offspring survival measurement http://www.ebi.ac.uk/efo/EFO_0009436 GCST006735 Genome-wide genotyping array 923 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Infant survival in continuous marriage (Proportion of children surviving at 1 year) 593 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 offspring survival measurement http://www.ebi.ac.uk/efo/EFO_0009436 GCST006736 Genome-wide genotyping array 593 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Number of miscarriages 981 Tibetan ancestry individuals NA Illumina [3507697] (imputed) 0 fertility measurement http://www.ebi.ac.uk/efo/EFO_0006923 GCST006737 Genome-wide genotyping array 981 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Number of miscarriages in continuous marriage 593 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 fertility measurement http://www.ebi.ac.uk/efo/EFO_0006923 GCST006738 Genome-wide genotyping array 593 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Proportion of miscarriages 981 Tibetan ancestry individuals NA Illumina [3507697] (imputed) 0 fertility measurement http://www.ebi.ac.uk/efo/EFO_0006923 GCST006739 Genome-wide genotyping array 981 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Proportion of miscarriages in continuous marriage 593 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 fertility measurement http://www.ebi.ac.uk/efo/EFO_0006923 GCST006740 Genome-wide genotyping array 593 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Number of stillbirths 981 Tibetan ancestry individuals NA Illumina [3507697] (imputed) 0 fertility measurement http://www.ebi.ac.uk/efo/EFO_0006923 GCST006741 Genome-wide genotyping array 981 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Number of stillbirths in continuous marriage 593 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 1 fertility measurement http://www.ebi.ac.uk/efo/EFO_0006923 GCST006742 Genome-wide genotyping array 593 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Proportion of stillbirths 981 Tibetan ancestry individuals NA Illumina [3507697] (imputed) 0 fertility measurement http://www.ebi.ac.uk/efo/EFO_0006923 GCST006743 Genome-wide genotyping array 981 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Proportion of stillbirths in continuous marriage 593 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 fertility measurement http://www.ebi.ac.uk/efo/EFO_0006923 GCST006744 Genome-wide genotyping array 593 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Number of pregnancies in continuous marriage 593 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 number of pregnancies measurement http://www.ebi.ac.uk/efo/EFO_0009438 GCST006772 Genome-wide genotyping array 593 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Number of twin births 981 Tibetan ancestry individuals NA Illumina [3507697] (imputed) 0 multiple births measurement http://www.ebi.ac.uk/efo/EFO_0009439 GCST006773 Genome-wide genotyping array 981 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Number of twin births in continuous marriage 593 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 multiple births measurement http://www.ebi.ac.uk/efo/EFO_0009439 GCST006774 Genome-wide genotyping array 593 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Age at last pregnancy 958 Tibetan ancestry individuals NA Illumina [3507463] (imputed) 0 age at last pregnancy measurement http://www.ebi.ac.uk/efo/EFO_0009440 GCST006775 Genome-wide genotyping array 958 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Age at last pregnancy in continuous marriage 593 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 age at last pregnancy measurement http://www.ebi.ac.uk/efo/EFO_0009440 GCST006776 Genome-wide genotyping array 593 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Age at first birth 972 Tibetan ancestry individuals NA Illumina [3507330] (imputed) 0 age at first birth measurement http://www.ebi.ac.uk/efo/EFO_0009101 GCST006769 Genome-wide genotyping array 972 2018-12-14 30188897 Jeong C 2018-09-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30188897 Detecting past and ongoing natural selection among ethnically Tibetan women at high altitude in Nepal. Age at first birth in continuous marriage 593 Tibetan ancestry individuals NA Illumina [~ 3500000] (imputed) 0 age at first birth measurement http://www.ebi.ac.uk/efo/EFO_0009101 GCST006770 Genome-wide genotyping array 593 2017-05-24 28059113 Hao J 2017-01-06 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28059113 Genome-wide association study identifies COL2A1 locus involved in the hand development failure of Kashin-Beck disease. Palmar length-width ratio in Kashin-Beck disease 90 Han Chinese ancestry individuals 403 Han Chinese ancestry individuals Affymetrix [532894] 0 Kashin-Beck disease http://www.ebi.ac.uk/efo/EFO_0006511 GCST004091 Genome-wide genotyping array 90 2017-06-27 28090653 Liu Y 2017-01-16 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/28090653 Genome-Wide Study Links PNPLA3 Variant With Elevated Hepatic Transaminase After Acute Lymphoblastic Leukemia Therapy. Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) up to 488 European ancestry cases, up to 111 African American cases, up to 60 Hispanic cases, up to 56 other ancestry cases NA Affymetrix, Illumina [NR] (imputed) 54 serum alanine aminotransferase measurement, response to combination chemotherapy http://www.ebi.ac.uk/efo/EFO_0004735, http://www.ebi.ac.uk/efo/EFO_0007965 GCST004250 Genome-wide genotyping array 715 2018-07-04 29538362 Jilling T 2018-03-14 Pediatr Res www.ncbi.nlm.nih.gov/pubmed/29538362 Surgical necrotizing enterocolitis in extremely premature neonates is associated with genetic variations in an intergenic region of chromosome eight. Surgical necrotising enterocolitis in extremely premature birth 20 African American cases, 6 Hispanic Caucasian cases, 4 European ancestry cases, 283 African American controls, 130 Hispanic Caucasian controls, 133 European ancestry controls, NA Illumina [8270200] (imputed) 29 necrotizing enterocolitis http://www.ebi.ac.uk/efo/EFO_0003928 GCST005800 Genome-wide genotyping array 576 2018-08-23 29934777 Witten A 2018-06-22 J Mol Med (Berl) www.ncbi.nlm.nih.gov/pubmed/29934777 Targeted resequencing of a locus for heparin-induced thrombocytopenia on chromosome 5 identified in a genome-wide association study. Heparin-induced thrombocytopenia 96 European ancestry cases, 96 European ancestry heparin-exposed controls 86 European ancestry cases, 86 European ancestry heparin-exposed controls Illumina [~ 351507] 3 response to heparin, Thrombocytopenia http://www.ebi.ac.uk/efo/EFO_0006816, http://purl.obolibrary.org/obo/HP_0001873 GCST006144 Genome-wide genotyping array 192 2017-05-11 28031287 Sasayama D 2016-11-26 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28031287 Genome-wide quantitative trait loci mapping of the human cerebrospinal fluid proteome. Cerebrospinal fluid biomarker levels 133 Japanese ancestry individuals. NA Illumina [514227] 65 cerebrospinal fluid biomarker measurement http://www.ebi.ac.uk/efo/EFO_0006794 GCST004000 Genome-wide genotyping array 133 2018-09-06 29898447 Alaraudanjoki VK 2018-06-13 Caries Res www.ncbi.nlm.nih.gov/pubmed/29898447 Genome-Wide Association Study of Erosive Tooth Wear in a Finnish Cohort. Erosive tooth wear (severe vs non-severe) 86 Finnish ancestry male severe erosion cases, 50 Finnish ancestry female severe erosion cases, 817 Finnish ancestry male non-severe erosion controls, 991 Finnish ancestry female non-severe erosion controls NA Illumina [NR] (imputed) 136 erosive tooth wear measurement http://www.ebi.ac.uk/efo/EFO_0009331 GCST006218 Genome-wide genotyping array 1944 2018-09-06 29898447 Alaraudanjoki VK 2018-06-13 Caries Res www.ncbi.nlm.nih.gov/pubmed/29898447 Genome-Wide Association Study of Erosive Tooth Wear in a Finnish Cohort. Erosive tooth wear (severe vs none or mild) 136 Finnish ancestry severe erosion cases, 1011 Finnish ancestry mild or no erosion controls NA Illumina [NR] (imputed) 23 erosive tooth wear measurement http://www.ebi.ac.uk/efo/EFO_0009331 GCST006226 Genome-wide genotyping array 1147 2018-08-14 29899525 Klimentidis YC 2018-06-13 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/29899525 Genome-wide association study of habitual physical activity in over 377,000 UK Biobank participants identifies multiple variants including CADM2 and APOE. Accelerometer-based physical activity measurement (fraction of time with accelerations >425 milli-gravities) 90,667 European ancestry individuals NA Affymetrix [11800000] (imputed) 2 physical activity measurement http://www.ebi.ac.uk/efo/EFO_0008002 GCST006079 Genome-wide genotyping array 90667 2018-08-16 29899525 Klimentidis YC 2018-06-13 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/29899525 Genome-wide association study of habitual physical activity in over 377,000 UK Biobank participants identifies multiple variants including CADM2 and APOE. Moderate to vigorous physical activity levels 377,234 European ancestry individuals NA Affymetrix [11800000] (imputed) 13 physical activity measurement http://www.ebi.ac.uk/efo/EFO_0008002 GCST006097 Genome-wide genotyping array 377234 2018-08-16 29899525 Klimentidis YC 2018-06-13 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/29899525 Genome-wide association study of habitual physical activity in over 377,000 UK Biobank participants identifies multiple variants including CADM2 and APOE. Vigorous physical activity 98,060 European ancestry active cases, 162,995 European ancestry inactive controls NA Affymetrix [11800000] (imputed) 9 physical activity measurement http://www.ebi.ac.uk/efo/EFO_0008002 GCST006098 Genome-wide genotyping array 261055 2018-08-16 29899525 Klimentidis YC 2018-06-13 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/29899525 Genome-wide association study of habitual physical activity in over 377,000 UK Biobank participants identifies multiple variants including CADM2 and APOE. Strenuous sports or other exercises 124,842 European ancestry active cases, 225,650 European ancestry inactive controls NA Affymetrix [11800000] (imputed) 8 physical activity measurement http://www.ebi.ac.uk/efo/EFO_0008002 GCST006100 Genome-wide genotyping array 350492 2018-08-16 29899525 Klimentidis YC 2018-06-13 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/29899525 Genome-wide association study of habitual physical activity in over 377,000 UK Biobank participants identifies multiple variants including CADM2 and APOE. Accelerometer-based physical activity measurement (average acceleration) 91,084 European ancestry individuals NA Affymetrix [11800000] (imputed) 5 physical activity measurement http://www.ebi.ac.uk/efo/EFO_0008002 GCST006099 Genome-wide genotyping array 91084 2017-02-15 28090565 Tsai EA 2016-05-26 Cell Mol Gastroenterol Hepatol www.ncbi.nlm.nih.gov/pubmed/28090565 THBS2 Is a Candidate Modifier of Liver Disease Severity in Alagille Syndrome. Liver disease severity in Alagille syndrome 97 European ancestry mild cases, 64 European ancestry severe cases NA Illumina [579677] 2 liver disease http://www.ebi.ac.uk/efo/EFO_0001421 GCST003616 Genome-wide genotyping array 161 2017-06-01 28053049 Sennblad B 2017-02-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28053049 Genome-wide association study with additional genetic and post-transcriptional analyses reveals novel regulators of plasma factor XI levels. Factor XI 16,169 European ancestry individuals 2,045 European ancestry individuals Affymetrix, Illumina [7353638] (imputed) 2 factor XI measurement http://www.ebi.ac.uk/efo/EFO_0004694 GCST004124 Genome-wide genotyping array 16169 2019-04-12 29785011 Zhu Z 2018-05-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29785011 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases. Asthma 14,085 European ancestry cases, 76,768 European ancestry controls 10,365 cases, 16,110 controls Affymetrix [74888535] (imputed) 6 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST007562 Genome-wide genotyping array 90853 2019-04-12 29785011 Zhu Z 2018-05-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29785011 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases. Allergic disease (asthma, hay fever or eczema) 25,685 European ancestry allergic diseases cases, 76,768 European ancestry controls NA Affymetrix [74888535] (imputed) 33 allergy, asthma http://www.ebi.ac.uk/efo/EFO_0003785, http://www.ebi.ac.uk/efo/EFO_0000270 GCST007563 Genome-wide genotyping array 102453 2019-04-12 29785011 Zhu Z 2018-05-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29785011 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases. Asthma or allergic disease (pleiotropy) 14,085 European asthma cases, 25,685 European ancestry allergic diseases cases, 76,768 European ancestry controls NA NR [74888535] (imputed) 38 allergy, asthma http://www.ebi.ac.uk/efo/EFO_0003785, http://www.ebi.ac.uk/efo/EFO_0000270 GCST007564 Genome-wide genotyping array 116538 2018-08-23 29915124 Marini S 2018-06-18 Stroke www.ncbi.nlm.nih.gov/pubmed/29915124 17p12 Influences Hematoma Volume and Outcome in Spontaneous Intracerebral Hemorrhage. Hematoma volume in lobar spontaneous intracerebral hemorrhage 228 European ancestry cases 71 European ancestry cases Illumina [7567631] (imputed) 1 intracerebral hemorrhage http://www.ebi.ac.uk/efo/EFO_0005669 GCST006139 Genome-wide genotyping array 228 2018-08-23 29915124 Marini S 2018-06-18 Stroke www.ncbi.nlm.nih.gov/pubmed/29915124 17p12 Influences Hematoma Volume and Outcome in Spontaneous Intracerebral Hemorrhage. Hematoma volume in non-lobar spontaneous intracerebral hemorrhage 166 European ancestry cases 169 European ancestry cases Illumina [7569876] (imputed) 1 intracerebral hemorrhage http://www.ebi.ac.uk/efo/EFO_0005669 GCST006140 Genome-wide genotyping array 166 2018-08-21 29917119 Schmit SL 2018-06-16 J Natl Cancer Inst www.ncbi.nlm.nih.gov/pubmed/29917119 Novel Common Genetic Susceptibility Loci for Colorectal Cancer. Colorectal cancer 36,948 European ancestry cases, 30,864 European ancestry controls 12,952 European ancestry cases, 48,383 European ancestry controls, 8,580 East Asian ancestry cases, 13,050 East Asian ancestry controls, 1,611 Hispanic cases, 4,330 Hispanic controls, 1,894 African American cases, 4,703 African American controls Affymetrix, Illumina [12931465] (imputed) 28 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST006131 Genome-wide genotyping array 67812 2019-04-03 30429480 Duffy DL 2018-11-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30429480 Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways. Nevus count or cutaneous melanoma 52,506 European ancestry individuals, 12,874 European ancestry cases, 23,203 European ancestry controls NA Affymetrix, Illumina [7850345] (imputed) 30 nevus count, cutaneous melanoma http://www.ebi.ac.uk/efo/EFO_0004632, http://www.ebi.ac.uk/efo/EFO_0000389 GCST007505 Genome-wide genotyping array 88583 2019-04-03 30429480 Duffy DL 2018-11-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30429480 Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways. Nevus count 52,506 European ancestry individuals NA Affymetrix, Illumina [up to 31337615] (imputed) 12 nevus count http://www.ebi.ac.uk/efo/EFO_0004632 GCST007504 Genome-wide genotyping array 52506 2017-05-11 28051079 Warner SC 2017-01-04 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/28051079 Genome-wide association scan of neuropathic pain symptoms post total joint replacement highlights a variant in the protein-kinase C gene. Possible neuropathic pain in post total joint replacement surgery for osteoarthritis 109 cases, 504 controls. NA Illumina [548381] 4 neuropathic pain http://www.ebi.ac.uk/efo/EFO_0005762 GCST003963 Genome-wide genotyping array 613 2017-05-17 28084903 Hallberg P 2017-01-13 Pharmacogenomics www.ncbi.nlm.nih.gov/pubmed/28084903 Genetic variants associated with angiotensin-converting enzyme inhibitor-induced cough: a genome-wide association study in a Swedish population. Cough in response to angiotensin-converting enzyme inhibitor drugs 123 European ancestry cases, 1,345 European and unknown ancestry controls, 1 Middle Eastern ancestry case NR Illumina [8600000] (imputed) 32 response to angiotensin-converting enzyme inhibitor, Cough http://www.ebi.ac.uk/efo/EFO_0005325, http://purl.obolibrary.org/obo/HP_0012735 GCST004049 Genome-wide genotyping array 1469 2019-01-14 30367059 Teumer A 2018-10-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30367059 Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation. Free thyroxine concentration 49,269 European ancestry individuals up to 22,383 European ancestry individuals Affymetrix, Illumina [8048941] (imputed) 19 thyroxine measurement http://www.ebi.ac.uk/efo/EFO_0005130 GCST006896 Genome-wide genotyping array 49269 2019-01-14 30367059 Teumer A 2018-10-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30367059 Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation. Thyroid stimulating hormone levels 54,288 European ancestry individuals up to 22,383 European ancestry individuals Affymetrix, Illumina [8048941] (imputed) 22 thyroid stimulating hormone measurement http://www.ebi.ac.uk/efo/EFO_0004748 GCST006899 Genome-wide genotyping array 54288 2019-01-14 30367059 Teumer A 2018-10-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30367059 Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation. Hypothyroidism 3,340 European ancestry cases, 49,983 European ancestry controls NA Affymetrix, Illumina [5965951] (imputed) 8 hypothyroidism http://www.ebi.ac.uk/efo/EFO_0004705 GCST006898 Genome-wide genotyping array 53323 2019-01-14 30367059 Teumer A 2018-10-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30367059 Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation. Hyperthyroidism 1,840 European ancestry cases, 49,983 European ancestry controls NA Affymetrix, Illumina [5965951] (imputed) 9 Hyperthyroidism http://www.ebi.ac.uk/efo/EFO_0009189 GCST006897 Genome-wide genotyping array 51823 2018-12-11 30223776 Hwang LD 2018-09-17 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/30223776 Bivariate genome-wide association analysis strengthens the role of bitter receptor clusters on chromosomes 7 and 12 in human bitter taste. Bitter taste perception (multivariate analysis) 1,999 European ancestry individuals from 929 twin families NA Illumina [4381914] (imputed) 11 sensory perception of bitter taste http://purl.obolibrary.org/obo/GO_0050913 GCST006703 Genome-wide genotyping array 2928 2018-12-11 30223776 Hwang LD 2018-09-17 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/30223776 Bivariate genome-wide association analysis strengthens the role of bitter receptor clusters on chromosomes 7 and 12 in human bitter taste. Bitter taste perception 1,999 European ancestry individuals from 929 twin families NA Illumina [4381914] (imputed) 6 sensory perception of bitter taste http://purl.obolibrary.org/obo/GO_0050913 GCST006704 Genome-wide genotyping array 2928 2018-08-13 29892015 Roselli C 2018-06-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29892015 Multi-ethnic genome-wide association study for atrial fibrillation. Atrial fibrillation 55,114 European ancestry cases, 482,295 European ancestry controls, 8,180 Japanese ancestry cases, 28,612 Japanese ancestry controls, 1,307 African American ancestry cases, 7,660 African American ancestry controls, 845 Hispanic cases, 4,177 Hispanic controls NA Affymetrix, Illumina [up to 12149979] (imputed) 228 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST006061 Genome-wide genotyping array 588190 2019-01-21 30374069 Styrkarsdottir U 2018-10-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30374069 Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis. Knee osteoarthritis 23,877 European ancestry cases, 562,153 European ancestry controls NA Affymetrix, Illumina [11554240] (imputed) 7 osteoarthritis, knee http://www.ebi.ac.uk/efo/EFO_0004616 GCST006925 Genome-wide genotyping array 586030 2019-01-21 30374069 Styrkarsdottir U 2018-10-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30374069 Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis. Osteoarthritis (hip) 17,151 European ancestry cases, 596,639 European ancestry controls NA Affymetrix, Illumina [11554240] (imputed) 32 osteoarthritis, hip http://www.ebi.ac.uk/efo/EFO_1000786 GCST006926 Genome-wide genotyping array 613790 2019-04-04 30452639 Butali A 2018-11-19 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30452639 Genomic analyses in african populations identify novel risk loci for cleft palate. Cleft lip with or without cleft palate 914 Sub-Saharan African ancestry cases, 2,159 Sub-Saharan African ancestry controls 401 Sub-Saharan African ancestry cases, 121 African American cases, 648 Sub-Saharan African ancestry controls, 186 African American controls Illumina [~ 17000000] (imputed) 0 cleft lip http://www.ebi.ac.uk/efo/EFO_0003959 GCST007510 Genome-wide genotyping array 3073 2019-04-04 30452639 Butali A 2018-11-19 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30452639 Genomic analyses in african populations identify novel risk loci for cleft palate. Cleft palate 205 Sub-Saharan African ancestry cases, 2,159 Sub-Saharan African ancestry controls 100 Sub-Saharan African ancestry cases, 79 African American cases, 648 Sub-Saharan African ancestry controls, 186 African American controls Illumina [~ 17000000] (imputed) 19 Cleft palate http://purl.obolibrary.org/obo/HP_0000175 GCST007509 Genome-wide genotyping array 2364 2019-01-28 30610202 Ruderfer DM 2019-01-04 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30610202 Significant shared heritability underlies suicide attempt and clinically predicted probability of attempting suicide. Suicide attempts 2,433 British ancestry cases, 334,766 British ancestry controls NA Affymetrix [7797387] (imputed) 0 attempted suicide http://www.ebi.ac.uk/efo/EFO_0004321 GCST006978 Genome-wide genotyping array 337199 2019-01-28 30610202 Ruderfer DM 2019-01-04 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30610202 Significant shared heritability underlies suicide attempt and clinically predicted probability of attempting suicide. Predicted suicide risk 24,546 European ancestry individuals NA Illumina [~ 9000000] (imputed) 2 suicide behaviour measurement http://www.ebi.ac.uk/efo/EFO_0006882 GCST006977 Genome-wide genotyping array 24546 2019-02-07 29768301 Ingle JN 2018-06-01 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/29768301 Germline genome-wide association studies in women receiving neoadjuvant chemotherapy with or without bevacizumab. Disease-free survival in breast cancer treated with chemotherapy with or without bevacizumab 890 cases 1,398 cases Illumina [> 7000000] (imputed) 0 disease free survival, response to antineoplastic agent http://www.ebi.ac.uk/efo/EFO_0000409, http://purl.obolibrary.org/obo/GO_0097327 GCST007046 Genome-wide genotyping array 890 2019-02-07 29768301 Ingle JN 2018-06-01 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/29768301 Germline genome-wide association studies in women receiving neoadjuvant chemotherapy with or without bevacizumab. Overall survival in breast cancer treated with chemotherapy with or without bevacizumab 891 cases 1,398 individuals Illumina [> 7000000] (imputed) 0 overall survival, response to antineoplastic agent http://www.ebi.ac.uk/efo/EFO_0000638, http://purl.obolibrary.org/obo/GO_0097327 GCST007049 Genome-wide genotyping array 891 2019-02-07 29768301 Ingle JN 2018-06-01 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/29768301 Germline genome-wide association studies in women receiving neoadjuvant chemotherapy with or without bevacizumab. Pathological complete response in breast cancer treated with chemotherapy with bevacizumab 147 cases with pathological complete response, 300 cases without pathological complete response 142 cases with pathological complete response, 591 cases without pathological complete response Illumina [> 7000000] (imputed) 0 response to bevacizumab, pathologic complete response measurement, response to antineoplastic agent http://www.ebi.ac.uk/efo/EFO_0005943, http://www.ebi.ac.uk/efo/EFO_0007771, http://purl.obolibrary.org/obo/GO_0097327 GCST007048 Genome-wide genotyping array 447 2019-02-07 29768301 Ingle JN 2018-06-01 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/29768301 Germline genome-wide association studies in women receiving neoadjuvant chemotherapy with or without bevacizumab. Pathological complete response in breast cancer treated with or without bevacizumab 236 cases with pathological complete response, 678 cases without pathological complete response 254 cases with pathological complete response, 1,144 cases without pathological complete response Illumina [> 7000000] (imputed) 0 pathologic complete response measurement, response to antineoplastic agent http://www.ebi.ac.uk/efo/EFO_0007771, http://purl.obolibrary.org/obo/GO_0097327 GCST007047 Genome-wide genotyping array 914 2017-09-22 28809852 Liu L 2017-08-15 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/28809852 The SNP-set based association study identifies ITGA1 as a susceptibility gene of attention-deficit/hyperactivity disorder in Han Chinese. Attention deficit hyperactivity disorder 1,033 Han Chinese ancestry cases, 950 Han Chinese ancestry controls 1,441 Han Chinese ancestry cases, 1,447 Han Chinese ancestry controls Affymetrix [717417] 1 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST004778 Genome-wide genotyping array 1983 2017-09-15 28757204 Manousaki D 2017-07-21 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/28757204 Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis. Vitamin D levels 2,619 whole genome sequenced European ancestry individuals, up to 38,213 European ancestry individuals, 1,442 individuals NA Affymetrix, Illumina [11026511] (imputed) 16 vitamin D measurement http://www.ebi.ac.uk/efo/EFO_0004631 GCST004726 Genome-wide genotyping array 42274 2017-09-05 28781888 Mobuchon L 2017-03-10 NPJ Genom Med www.ncbi.nlm.nih.gov/pubmed/28781888 A GWAS in uveal melanoma identifies risk polymorphisms in the CLPTM1L locus. Uveal melanoma 259 European ancestry cases, 401 European ancestry controls 276 French cases, 184 European ancestry controls Illumina [866782] 2 Uveal Melanoma http://www.ebi.ac.uk/efo/EFO_1000616 GCST004661 Genome-wide genotyping array 660 2017-09-29 28776340 Son CN 2017-09-01 J Korean Med Sci www.ncbi.nlm.nih.gov/pubmed/28776340 ABCG2 Polymorphism Is Associated with Hyperuricemia in a Study of a Community-Based Korean Cohort. Hyperuricemia 234 Korean ancestry cases, 3,413 Korean ancestry controls NA Illumina [748585] 2 uric acid measurement http://www.ebi.ac.uk/efo/EFO_0004761 GCST004825 Genome-wide genotyping array 3647 2017-09-25 28776448 Beaudoin JJ 2017-08-04 Scand J Gastroenterol www.ncbi.nlm.nih.gov/pubmed/28776448 An exploratory genome-wide analysis of genetic risk for alcoholic hepatitis. Alcoholic hepatitis 90 European ancestry heavy drinking cases, 93 European ancestry heavy drinking controls NA Illumina [819401] 0 Hepatitis, Alcoholic http://www.ebi.ac.uk/efo/EFO_1001345 GCST004784 Genome-wide genotyping array 183 2017-10-03 28806749 Leo PJ 2017-08-14 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28806749 Defining the genetic susceptibility to cervical neoplasia-A genome-wide association study. Cervical cancer 2,866 European ancestry cases, 6,481 European ancestry controls NA Illumina [10863230] (imputed) 14 cervical carcinoma http://www.ebi.ac.uk/efo/EFO_0001061 GCST004833 Genome-wide genotyping array 9347 2018-03-05 29278698 Zagajewska K 2017-12-23 Exp Eye Res www.ncbi.nlm.nih.gov/pubmed/29278698 GWAS links variants in neuronal development and actin remodeling related loci with pseudoexfoliation syndrome without glaucoma. Pseudoexfoliation syndrome 103 European ancestry cases, 106 European ancestry controls NA Illumina [NR] 1 exfoliation syndrome http://www.ebi.ac.uk/efo/EFO_0004235 GCST005347 Genome-wide genotyping array 209 2018-03-08 29293525 Gudmundsdottir V 2018-01-02 PLoS One www.ncbi.nlm.nih.gov/pubmed/29293525 Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study. GLP-1-stimulated insulin secretion 33 monozygotic twin pairs, 14 dizygotic twin pairs, 32 individuals 100 European ancestry individuals Illumina [6600000] (imputed) 0 GLP-1-stimulated insulin response http://www.ebi.ac.uk/efo/EFO_0008531 GCST005353 Genome-wide genotyping array 79 2018-02-22 29309628 Beaumont RN 2018-01-03 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/29309628 Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. Offspring birth weight 68,258 European ancestry women 18,319 European ancestry women Affymetrix, Illumina, Perlegen [up to 8741107] (imputed) 2 birth weight, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0004344, http://www.ebi.ac.uk/efo/EFO_0005939 GCST005314 Genome-wide genotyping array 68258 2018-09-20 29404214 Andaleon A 2018-01-29 PeerJ www.ncbi.nlm.nih.gov/pubmed/29404214 Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels. LDL cholesterol 1,017 Yoruban ancestry individuals, 1,765 Filipino ancestry individuals NA Affymetrix, Illumina [up to 12553142] (imputed) 0 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST006307 Genome-wide genotyping array 2782 2018-09-20 29404214 Andaleon A 2018-01-29 PeerJ www.ncbi.nlm.nih.gov/pubmed/29404214 Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels. Triglycerides 1,017 Yoruban ancestry individuals, 1,765 Filipino ancestry individuals NA Affymetrix, Illumina [up to 12553142] (imputed) 4 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST006308 Genome-wide genotyping array 2782 2018-10-24 29404214 Andaleon A 2018-01-29 PeerJ www.ncbi.nlm.nih.gov/pubmed/29404214 Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels. Cholesterol, total 1,017 Yoruban ancestry individuals,1,765 Filipino ancestry individuals 188,577 European and other ancestry individuals Illumina [4454201] (imputed) 1 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST006469 Targeted genotyping array [XBEP method] 2782 2018-10-24 29404214 Andaleon A 2018-01-29 PeerJ www.ncbi.nlm.nih.gov/pubmed/29404214 Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels. HDL cholesterol 1,017 Yoruban ancestry individuals, 1,765 Filipino ancestry individuals 188,577 European and other ancestry individuals Illumina [4454201] (imputed) 1 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST006470 Targeted genotyping array [XBEP method] 2782 2018-10-24 29404214 Andaleon A 2018-01-29 PeerJ www.ncbi.nlm.nih.gov/pubmed/29404214 Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels. LDL cholesterol 1,017 Yoruban ancestry individuals, 1,765 Filipino ancestry individuals 188,577 European and other ancestry individuals Illumina [4454201] (imputed) 0 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST006471 Targeted genotyping array [XBEP method] 2782 2018-10-24 29404214 Andaleon A 2018-01-29 PeerJ www.ncbi.nlm.nih.gov/pubmed/29404214 Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels. Triglyceride levels 1,017 Yoruban ancestry individuals, 1,765 Filipino individuals 188,577 European and other ancestry individuals Illumina [4454201] (imputed) 1 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST006472 Targeted genotyping array [XBEP method] 2782 2018-09-20 29404214 Andaleon A 2018-01-29 PeerJ www.ncbi.nlm.nih.gov/pubmed/29404214 Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels. Cholesterol, total 1,017 Yoruban ancestry individuals, 1,765 Filipino ancestry individuals NA Affymetrix, Illumina [up to 12553142] (imputed) 0 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST006305 Genome-wide genotyping array 2782 2018-09-20 29404214 Andaleon A 2018-01-29 PeerJ www.ncbi.nlm.nih.gov/pubmed/29404214 Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels. HDL cholesterol 1,017 Yoruban ancestry individuals, 1,765 Filipino ancestry individuals NA Affymetrix, Illumina [up to 12553142] (imputed) 4 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST006306 Genome-wide genotyping array 2782 2018-07-04 29425463 Bime C 2018-02-09 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/29425463 Genome Wide Association Study in African Americans with Acute Respiratory Distress Syndrome Identifies the Selectin P Ligand Gene as a Risk Factor. Acute respiratory distress syndrome 232 African American ancestry cases, 162 African American ancestry controls with sepsis or other risk factors 140 African American cases, 269 European ancestry cases, 222 African American ancestry controls with sepsis, 338 European ancestry controls with sepsis Affymetrix [1428996] 0 acute respiratory distress syndrome http://www.ebi.ac.uk/efo/EFO_1000637 GCST005805 Genome-wide genotyping array 394 2018-05-08 23143596 Eyre S 2012-12-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23143596 High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Rheumatoid arthritis up to 13,838 European ancestry cases, up to 33,742 European ancestry controls NA Illumina [129464] (imputed) 50 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST005569 Genome-wide genotyping array, Targeted genotyping array [ImmunoChip] 47580 2018-05-08 23143596 Eyre S 2012-12-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23143596 High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Rheumatoid arthritis (ACPA-negative) 3,297 European ancestry cases, 15,870 European ancestry controls NA Illumina [129464] 2 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST005567 Targeted genotyping array [ImmunoChip] 19167 2018-05-08 23143596 Eyre S 2012-12-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23143596 High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Rheumatoid arthritis (ACPA-positive) up to 9,585 European ancestry cases, up to 33,742 European ancestry controls NA Illumina [129464] (imputed) 56 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST005568 Genome-wide genotyping array, Targeted genotyping array [ImmunoChip] 43327 2017-11-06 28957430 Winsvold BS 2017-09-28 PLoS One www.ncbi.nlm.nih.gov/pubmed/28957430 Shared genetic risk between migraine and coronary artery disease: A genome-wide analysis of common variants. Migraine or coronary artery disease 37,653 coronary artery disease cases, 22,120 migraine cases, 171,108 controls NA Affymetrix, Illumina [NR] 0 migraine disorder, coronary artery disease http://www.ebi.ac.uk/efo/EFO_0003821, http://www.ebi.ac.uk/efo/EFO_0001645 GCST004944 Genome-wide genotyping array 230881 2018-09-20 28869591 Kemp JP 2017-09-04 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28869591 Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis. Heel bone mineral density 76,067 European ancestry women, 66,420 European ancestry men NA NR [17166351] (imputed) 766 heel bone mineral density http://www.ebi.ac.uk/efo/EFO_0009270 GCST006288 Genome-wide genotyping array 142487 2018-07-04 29769521 Ramirez J 2018-05-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29769521 Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system. Heart rate response to exercise up to 35,455 European ancestry females, up to 31,802 European ancestry males NA Affymetrix [~ 7800000] (imputed) 32 heart rate response to exercise http://www.ebi.ac.uk/efo/EFO_0009184 GCST005787 Genome-wide genotyping array 67257 2018-07-04 29769521 Ramirez J 2018-05-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29769521 Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system. Heart rate response to recovery post exercise up to 35,455 European ancestry females, up to 31,802 European ancestry males NA Affymetrix [~ 7800000] (imputed) 29 heart rate response to recovery post exercise http://www.ebi.ac.uk/efo/EFO_0009185 GCST005788 Genome-wide genotyping array 67257 2018-07-04 29769521 Ramirez J 2018-05-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29769521 Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system. Resting heart rate 67,062 European ancestry individuals NA Affymetrix [~ 7800000] (imputed) 30 resting heart rate http://www.ebi.ac.uk/efo/EFO_0004351 GCST005789 Genome-wide genotyping array 67062 2017-09-22 28762467 Wadelius M 2017-08-01 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/28762467 Sulfasalazine-Induced Agranulocytosis Is Associated With the Human Leukocyte Antigen Locus. Sulfasalazine-induced agranulocytosis 36 European ancestry cases, 5,170 European ancestry untreated controls NA Illumina [9380034] (imputed) 32 response to sulfasalazine, Drug-induced agranulocytosis http://www.ebi.ac.uk/efo/EFO_0008324, http://purl.obolibrary.org/obo/HP_0012235 GCST004781 Genome-wide genotyping array 5206 2018-01-30 29288229 McCormack M 2017-12-29 Neurology www.ncbi.nlm.nih.gov/pubmed/29288229 Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients. Antiepileptic drug-induced maculopapular exanthema 259 European ancestry cases, 979 European ancestry tolerant controls, 116 Han Chinese ancestry cases, 342 Han Chinese ancestry tolerant controls NA Illumina [at least 3693290] (imputed) 0 maculopapular eruption, response to anticonvulsant http://www.ebi.ac.uk/efo/EFO_1001253, http://purl.obolibrary.org/obo/GO_0036277 GCST005197 Genome-wide genotyping array 1696 2018-01-30 29288229 McCormack M 2017-12-29 Neurology www.ncbi.nlm.nih.gov/pubmed/29288229 Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients. Carbamazepine-induced maculopapular exanthema 95 European ancestry cases, 869 European ancestry tolerant controls, 85 Han Chinese ancestry cases, 197 Han Chinese ancestry tolerant controls NA Illumina [at least 3693290] (imputed) 1 maculopapular eruption, response to carbamazepine http://www.ebi.ac.uk/efo/EFO_1001253, http://www.ebi.ac.uk/efo/EFO_0008484 GCST005198 Genome-wide genotyping array 1246 2018-01-30 29288229 McCormack M 2017-12-29 Neurology www.ncbi.nlm.nih.gov/pubmed/29288229 Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients. Lamotrigine-induced maculopapular exanthema 118 European ancestry cases, 812 European ancestry tolerant controls, 16 Han Chinese ancestry cases, 32 Han Chinese ancestry tolerant controls NA Illumina [at least 3693290] (imputed) 0 response to lamotrigine, maculopapular eruption http://www.ebi.ac.uk/efo/EFO_0007661, http://www.ebi.ac.uk/efo/EFO_1001253 GCST005199 Genome-wide genotyping array 978 2018-01-30 29288229 McCormack M 2017-12-29 Neurology www.ncbi.nlm.nih.gov/pubmed/29288229 Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients. Phenytoin-induced maculopapular exanthema 52 European ancestry cases, 472 European ancestry tolerant controls, 22 Han Chinese ancestry cases, 58 Han Chinese ancestry tolerant controls 13 European ancestry cases, 88 European ancestry tolerant controls Illumina [at least 3693290] (imputed) 1 maculopapular eruption, response to phenytoin http://www.ebi.ac.uk/efo/EFO_1001253, http://www.ebi.ac.uk/efo/EFO_0006345 GCST005200 Genome-wide genotyping array 604 2018-02-19 29290336 Nielsen JB 2018-01-04 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29290336 Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development. Atrial fibrillation 6,337 European ancestry cases, 61,607 European ancestry controls 30,679 European ancestry cases, 278,895 European ancestry controls Illumina [8952551] (imputed) 10 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST005306 Genome-wide genotyping array 67944 2018-07-24 29868224 Sallah N 2017-11-27 Glob Health Epidemiol Genom www.ncbi.nlm.nih.gov/pubmed/29868224 Whole-genome association study of antibody response to Epstein-Barr virus in an African population: a pilot. Epstein Barr virus nuclear antigen 1 IgG levels 1,473 Ugandan ancestry individuals, 2,162 European ancestry individuals NA Illumina [up to 17000000] (imputed) 2 Epstein Barr virus nuclear antigen 1 IgG measurement http://www.ebi.ac.uk/efo/EFO_0007790 GCST005963 Genome-wide genotyping array, Genome-wide sequencing 3635 2018-07-23 29868224 Sallah N 2017-11-27 Glob Health Epidemiol Genom www.ncbi.nlm.nih.gov/pubmed/29868224 Whole-genome association study of antibody response to Epstein-Barr virus in an African population: a pilot. Epstein Barr virus nuclear antigen 1 IgG seropositivity 1,201 Ugandan ancestry cases, 361 Ugandan ancestry controls NA Illumina [~ 17000000] (imputed) 1 Epstein Barr virus nuclear antigen-1 seropositivity http://www.ebi.ac.uk/efo/EFO_0009271 GCST005941 Genome-wide genotyping array, Genome-wide sequencing 1562 2018-07-23 29868224 Sallah N 2017-11-27 Glob Health Epidemiol Genom www.ncbi.nlm.nih.gov/pubmed/29868224 Whole-genome association study of antibody response to Epstein-Barr virus in an African population: a pilot. Viral capsid antigen IgG levels 1,473 Ugandan ancestry individuals NA Illumina [~ 17000000] (imputed) 0 Epstein Barr viral capsid antigen IgG measurement http://www.ebi.ac.uk/efo/EFO_0009274 GCST005942 Genome-wide genotyping array, Genome-wide sequencing 1473 2018-07-23 29868224 Sallah N 2017-11-27 Glob Health Epidemiol Genom www.ncbi.nlm.nih.gov/pubmed/29868224 Whole-genome association study of antibody response to Epstein-Barr virus in an African population: a pilot. Viral capsid antigen IgG seropositivity 1,344 Ugandan ancestry cases, 218 Ugandan ancestry controls NA Illumina [~ 17000000] (imputed) 4 Epstein Barr viral capsid antigen seropositivity http://www.ebi.ac.uk/efo/EFO_0009272 GCST005944 Genome-wide genotyping array, Genome-wide sequencing 1562 2018-07-23 29868224 Sallah N 2017-11-27 Glob Health Epidemiol Genom www.ncbi.nlm.nih.gov/pubmed/29868224 Whole-genome association study of antibody response to Epstein-Barr virus in an African population: a pilot. Epstein-Barr virus immune response (multivariate analysis) 1,473 Ugandan ancestry individuals NA Illumina [~ 17000000] (imputed) 1 anti-Epstein Barr virus antibody measurement http://www.ebi.ac.uk/efo/EFO_0009273 GCST005943 Genome-wide genotyping array, Genome-wide sequencing 1473 2018-02-28 29293537 Gorlova OY 2018-01-02 PLoS One www.ncbi.nlm.nih.gov/pubmed/29293537 Gene-level association analysis of systemic sclerosis: A comparison of African-Americans and White populations. Systemic sclerosis 1,833 European ancestry cases, 3,466 European ancestry controls, 291 African American cases, 260 African American controls NA Illumina [~ 2500000] (imputed) 6 systemic scleroderma http://www.ebi.ac.uk/efo/EFO_0000717 GCST005336 Genome-wide genotyping array 5850 2018-02-28 29293537 Gorlova OY 2018-01-02 PLoS One www.ncbi.nlm.nih.gov/pubmed/29293537 Gene-level association analysis of systemic sclerosis: A comparison of African-Americans and White populations. Limited cutaneous systemic scleroderma 1,087 European ancestry cases, 3,466 European ancestry controls, 82 African American cases, 260 African American controls NA Illumina [~ 2500000] (imputed) 6 limited scleroderma http://www.ebi.ac.uk/efo/EFO_1001017 GCST005334 Genome-wide genotyping array 4895 2018-02-28 29293537 Gorlova OY 2018-01-02 PLoS One www.ncbi.nlm.nih.gov/pubmed/29293537 Gene-level association analysis of systemic sclerosis: A comparison of African-Americans and White populations. Diffuse cutaneous systemic sclerosis 574 European ancestry cases, 3,466 European ancestry controls, 201 African American cases, 260 African American controls NA Illumina [~ 2500000] (imputed) 3 diffuse scleroderma http://www.ebi.ac.uk/efo/EFO_0000404 GCST005335 Genome-wide genotyping array 4501 2018-02-28 29293537 Gorlova OY 2018-01-02 PLoS One www.ncbi.nlm.nih.gov/pubmed/29293537 Gene-level association analysis of systemic sclerosis: A comparison of African-Americans and White populations. Systemic sclerosis (anti-centromere-positive) 671 European ancestry cases, 3,466 European ancestry controls, 21 African American cases, 260 African American controls NA Illumina [~ 2500000] (imputed) 2 anti-centromere-antibody-positive systemic scleroderma http://www.ebi.ac.uk/efo/EFO_0008536 GCST005333 Genome-wide genotyping array 4418 2018-02-28 29293537 Gorlova OY 2018-01-02 PLoS One www.ncbi.nlm.nih.gov/pubmed/29293537 Gene-level association analysis of systemic sclerosis: A comparison of African-Americans and White populations. Systemic sclerosis (anti-topoisomerase-positive) 347 European ancestry cases, 3,466 European ancestry controls, 69 African American cases, 260 African American controls NA Illumina [~ 2500000] (imputed) 2 anti-topoisomerase-I-antibody-positive systemic scleroderma http://www.ebi.ac.uk/efo/EFO_0008537 GCST005332 Genome-wide genotyping array 4142 2018-04-30 29293537 Gorlova OY 2018-01-02 PLoS One www.ncbi.nlm.nih.gov/pubmed/29293537 Gene-level association analysis of systemic sclerosis: A comparison of African-Americans and White populations. Systemic sclerosis 1,833 European ancestry cases, 3,466 European ancestry controls, 291 African American cases, 260 African American controls NA Illumina [126270] 10 systemic scleroderma http://www.ebi.ac.uk/efo/EFO_0000717 GCST005554 Targeted genotyping array [Immunochip] 5850 2018-04-30 29293537 Gorlova OY 2018-01-02 PLoS One www.ncbi.nlm.nih.gov/pubmed/29293537 Gene-level association analysis of systemic sclerosis: A comparison of African-Americans and White populations. Limited cutaneous systemic scleroderma 1,087 European ancestry cases, 3,466 European ancestry controls, 82 African American cases, 260 African American controls NA Illumina [126270] 8 limited scleroderma http://www.ebi.ac.uk/efo/EFO_1001017 GCST005555 Targeted genotyping array [Immunochip] 4895 2018-04-30 29293537 Gorlova OY 2018-01-02 PLoS One www.ncbi.nlm.nih.gov/pubmed/29293537 Gene-level association analysis of systemic sclerosis: A comparison of African-Americans and White populations. Diffuse cutaneous systemic sclerosis 574 European ancestry cases, 3,466 European ancestry controls, 201 African American cases, 260 African American controls NA Illumina [126270] 3 diffuse scleroderma http://www.ebi.ac.uk/efo/EFO_0000404 GCST005553 Targeted genotyping array [Immunochip] 4501 2018-04-30 29293537 Gorlova OY 2018-01-02 PLoS One www.ncbi.nlm.nih.gov/pubmed/29293537 Gene-level association analysis of systemic sclerosis: A comparison of African-Americans and White populations. Systemic sclerosis (anti-centromere-positive) 671 European ancestry cases, 3,466 European ancestry controls, 21 African American cases, 260 African American controls NA Illumina [126270] 3 anti-centromere-antibody-positive systemic scleroderma http://www.ebi.ac.uk/efo/EFO_0008536 GCST005552 Targeted genotyping array [Immunochip] 4418 2018-04-30 29293537 Gorlova OY 2018-01-02 PLoS One www.ncbi.nlm.nih.gov/pubmed/29293537 Gene-level association analysis of systemic sclerosis: A comparison of African-Americans and White populations. Systemic sclerosis (anti-topoisomerase-positive) 347 European ancestry cases, 3,466 European ancestry controls, 69 African American cases, 260 African American controls NA Illumina [126270] 4 anti-topoisomerase-I-antibody-positive systemic scleroderma http://www.ebi.ac.uk/efo/EFO_0008537 GCST005551 Targeted genotyping array [Immunochip] 4142 2018-07-04 29422769 Shah RL 2018-02-05 Mol Vis www.ncbi.nlm.nih.gov/pubmed/29422769 A genome-wide association study of corneal astigmatism: The CREAM Consortium. Corneal astigmatism 9,293 European ancestry cases, 12,957 European ancestry controls, 4,349 Asian ancestry cases, 4,771 Asian ancestry controls NA NR [~ 55000000] (imputed) 16 Corneal astigmatism http://www.ebi.ac.uk/efo/EFO_1002040 GCST005803 Genome-wide genotyping array 31370 2018-07-20 29777097 Marioni RE 2018-05-18 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29777097 GWAS on family history of Alzheimer's disease. Paternal history of Alzheimer's disease 14,338 British ancestry cases, 245,941 British ancestry controls NA Affymetrix [7795605] (imputed) 2 family history of Alzheimer’s disease http://www.ebi.ac.uk/efo/EFO_0009268 GCST005920 Genome-wide genotyping array 260279 2018-07-20 29777097 Marioni RE 2018-05-18 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29777097 GWAS on family history of Alzheimer's disease. Family history of Alzheimer's disease up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 European ancestry individuals with no parental history of Alzheimer's disease NA Affymetrix [7795605] (imputed) 61 family history of Alzheimer’s disease http://www.ebi.ac.uk/efo/EFO_0009268 GCST005921 Genome-wide genotyping array 314278 2018-07-20 29777097 Marioni RE 2018-05-18 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29777097 GWAS on family history of Alzheimer's disease. Alzheimer's disease or family history of Alzheimer's disease up to 42,034 British ancestry individuals with parental history of Alzheimer's disease, at least 272,244 British ancestry individuals with no parental history of Alzheimer's disease, 25,580 Alzheimer's disease cases, 48,466 controls NA Affymetrix [7795605] (imputed) 221 Alzheimer's disease, family history of Alzheimer’s disease http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0009268 GCST005922 Genome-wide genotyping array 388324 2018-07-20 29777097 Marioni RE 2018-05-18 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29777097 GWAS on family history of Alzheimer's disease. Maternal history of Alzheimer's disease 27,696 British ancestry cases, 260,980 British ancestry controls NA Affymetrix [7795605] (imputed) 6 family history of Alzheimer’s disease http://www.ebi.ac.uk/efo/EFO_0009268 GCST005923 Genome-wide genotyping array 288676 2017-10-19 28902444 Stein MB 2017-09-13 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/28902444 Genomewide association studies of suicide attempts in US soldiers. Suicide attempts 311 European ancestry cases, 83 African cases, 79 Hispanic/Latino cases, 6,228 European ancestry controls, 1,689 African controls, 1,861 Hispanic/Latino controls 89 European ancestry cases, 17 African cases, 29 Hispanic/Latino cases, 4,594 European ancestry controls, 823 African controls, 1,462 Hispanic/Latino controls Illumina [at least 360704] (imputed) 0 attempted suicide http://www.ebi.ac.uk/efo/EFO_0004321 GCST004893 Genome-wide genotyping array 10251 2017-11-21 29016859 Ogura Y 2017-10-15 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/29016859 A functional variant in MIR4300HG, the host gene of microRNA MIR4300 is associated with progression of adolescent idiopathic scoliosis. Curve progression in adolescent idiopathic scoliosis 1,105 Japanese ancestry AIS progression cases, 832 Japanese ancestry AIS non-progression controls 323 Japanese ancestry AIS progression cases, 283 Japanese ancestry AIS non-progression controls Illumina [7521072] (imputed) 1 adolescent idiopathic scoliosis, disease progression measurement http://www.ebi.ac.uk/efo/EFO_0005423, http://www.ebi.ac.uk/efo/EFO_0008336 GCST004981 Genome-wide genotyping array 1937 2018-02-07 29299148 Liu W 2017-11-25 Oncotarget www.ncbi.nlm.nih.gov/pubmed/29299148 Cancer risk susceptibility loci in a Swedish population. Cancer 3,555 Swedish ancestry cases, 15,581 Swedish ancestry controls NA Illumina [226883] 26 cancer http://www.ebi.ac.uk/efo/EFO_0000311 GCST005275 Genome-wide genotyping array 19136 2018-06-21 27362418 Zhang H 2016-06-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/27362418 A Powerful Procedure for Pathway-Based Meta-analysis Using Summary Statistics Identifies 43 Pathways Associated with Type II Diabetes in European Populations. Type 2 diabetes 19,809 European ancestry cases, 111,181 European ancestry controls 6,952 East Asian ancestry cases, 11,865 East Asian ancestry controls NR [up to 2500000] (imputed) 1 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST005716 Genome-wide genotyping array 130990 2018-01-18 29263402 Han Y 2017-12-20 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29263402 Genome-wide association study identifies a missense variant at APOA5 for coronary artery disease in Multi-Ethnic Cohorts from Southeast Asia. Coronary artery disease 1,778 Chinese ancestry cases, 391 Malay ancestry cases, 5,164 Chinese ancestry controls, 2,212 Malay ancestry controls 291 Asian Indian cases, 1,848 Asian Indian controls Illumina [at least 5827330] (imputed) 2 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST005172 Genome-wide genotyping array 9545 2018-01-30 29266176 Inaba H 2017-12-19 Cancer www.ncbi.nlm.nih.gov/pubmed/29266176 Bone mineral density in children with acute lymphoblastic leukemia. Bone mineral density change response to combined chemotherapy in acute lymphoblastic leukemia 235 European ancestry cases, 48 African American ancestry cases, 13 cases NA Affymetrix [448281] 4 spine bone mineral density change measurement, response to combination chemotherapy http://www.ebi.ac.uk/efo/EFO_0008474, http://www.ebi.ac.uk/efo/EFO_0007965 GCST005214 Genome-wide genotyping array 296 2018-01-29 29212778 van der Harst P 2017-12-06 Circ Res www.ncbi.nlm.nih.gov/pubmed/29212778 Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease. Coronary artery disease 34,541 cases, 261,984 controls 88,192 cases, 162,544 controls Affymetrix [7947838] (imputed) 259 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST005194 Genome-wide genotyping array 296525 2018-01-29 29212778 van der Harst P 2017-12-06 Circ Res www.ncbi.nlm.nih.gov/pubmed/29212778 Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease. Coronary artery disease up to 122,733 cases, up to 424,528 controls NA Affymetrix [at least 7947838] (imputed) 148 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST005195 Genome-wide genotyping array 547261 2018-01-29 29212778 van der Harst P 2017-12-06 Circ Res www.ncbi.nlm.nih.gov/pubmed/29212778 Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease. Coronary artery disease 88,192 cases, 162,544 controls 34,541 cases, 261,984 controls NR [8041861] (imputed) 254 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST005196 Genome-wide genotyping array 250736 2018-07-23 29296746 Ma Q 2017-06-19 Blood Adv www.ncbi.nlm.nih.gov/pubmed/29296746 Genetic variants in ADAMTS13 as well as smoking are major determinants of plasma ADAMTS13 levels. ADAMTS13 levels 3,238 European ancestry individuals NA Illumina [5821939] (imputed) 4 a disintegrin and metalloproteinase with thrombospondin motifs 13 http://www.ebi.ac.uk/efo/EFO_0008011 GCST005945 Genome-wide genotyping array 3238 2017-09-22 28843169 Neumann A 2017-08-12 Psychoneuroendocrinology www.ncbi.nlm.nih.gov/pubmed/28843169 The low single nucleotide polymorphism heritability of plasma and saliva cortisol levels. Cortisol levels (saliva) 7,703 European ancestry individuals NA Illumina, Perlegen [2156702] (imputed) 10 cortisol measurement http://www.ebi.ac.uk/efo/EFO_0005843 GCST004780 Genome-wide genotyping array 7703 2017-02-19 27559109 Bustamante M 2016-08-23 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/27559109 A genome-wide association meta-analysis of diarrhoeal disease in young children identifies FUT2 locus and provides plausible biological pathways. diarrhoeal disease at age 1 2,693 European ancestry cases, 3,065 European ancestry controls 2,302 European ancestry cases, 1,466 European ancestry controls Illumina [at least 5400000] (imputed) 1 Diarrhea http://purl.obolibrary.org/obo/HP_0002014 GCST003626 Genome-wide genotyping array 5758 2017-02-19 27559109 Bustamante M 2016-08-23 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/27559109 A genome-wide association meta-analysis of diarrhoeal disease in young children identifies FUT2 locus and provides plausible biological pathways. diarrhoeal disease at age 1 with doctor diagnosis 1,339 European ancestry cases, 5,064 European ancestry controls 1,411 European ancestry cases, 6,054 European ancestry controls Affymetrix, Illumina [at least 5400000] (imputed) 1 Diarrhea http://purl.obolibrary.org/obo/HP_0002014 GCST003625 Genome-wide genotyping array 6403 2017-02-19 27559109 Bustamante M 2016-08-23 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/27559109 A genome-wide association meta-analysis of diarrhoeal disease in young children identifies FUT2 locus and provides plausible biological pathways. diarrhoeal disease at age 2 2,855 European ancestry cases, 2,753 European ancestry controls 1,972 European ancestry cases, 1,544 European ancestry controls Illumina [at least 5400000] (imputed) 1 Diarrhea http://purl.obolibrary.org/obo/HP_0002014 GCST003623 Genome-wide genotyping array 5608 2017-02-19 27559109 Bustamante M 2016-08-23 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/27559109 A genome-wide association meta-analysis of diarrhoeal disease in young children identifies FUT2 locus and provides plausible biological pathways. diarrhoeal disease at age 2 with doctor diagnosis 990 European ancestry cases, 5,243 European ancestry controls 1,274 European ancestry cases, 6,448 European ancestry controls Affymetrix, Illumina [at least 5400000] (imputed) 1 Diarrhea http://purl.obolibrary.org/obo/HP_0002014 GCST003624 Genome-wide genotyping array 6233 2017-02-15 27244555 Li Y 2016-05-31 Nat Commun www.ncbi.nlm.nih.gov/pubmed/27244555 Genome-wide association study identifies 8p21.3 associated with persistent hepatitis B virus infection among Chinese. Persistent hepatitis B virus infection 1,251 Chinese ancestry persistently infected cases, 1,057 Chinese ancestry spontaneously recovered controls 3,905 Chinese ancestry persistently infected cases, 3,356 Chinese ancestry spontaneously recovered controls Affymetrix, Illumina [up to 4494311] (imputed) 4 hepatitis B virus infection, Susceptibility to viral and mycobacterial infections http://www.ebi.ac.uk/efo/EFO_0004197, http://www.orpha.net/ORDO/Orphanet_391311 GCST003615 Genome-wide genotyping array 2308 2018-05-11 29436472 Casalone E 2018-02-07 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/29436472 A novel variant in GLIS3 is associated with osteoarthritis. Osteoarthritis of the hip or knee (with total joint replacement) 5,414 European ancestry cases, 9,939 European ancestry healthy controls 17,894 European ancestry cases, 89,470 European ancestry healthy controls Illumina [270934] 1 osteoarthritis, hip, osteoarthritis, knee http://www.ebi.ac.uk/efo/EFO_1000786, http://www.ebi.ac.uk/efo/EFO_0004616 GCST005571 Genome-wide genotyping array 15353 2018-05-11 29436472 Casalone E 2018-02-07 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/29436472 A novel variant in GLIS3 is associated with osteoarthritis. Osteoarthritis of the hip or knee 5,414 European ancestry cases, 9,939 European ancestry healthy controls 12,658 European ancestry cases, 50,898 European ancestry healthy controls Illumina [270934] 2 osteoarthritis, hip, osteoarthritis, knee http://www.ebi.ac.uk/efo/EFO_1000786, http://www.ebi.ac.uk/efo/EFO_0004616 GCST005573 Genome-wide genotyping array 15353 2018-05-11 29436472 Casalone E 2018-02-07 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/29436472 A novel variant in GLIS3 is associated with osteoarthritis. Osteoarthritis of the hip (with total joint replacement) 2,517 European ancestry cases, 9,939 European ancestry healthy controls 2,282 European ancestry cases, 9,193 European ancestry healthy controls Illumina [270934] 6 osteoarthritis, hip http://www.ebi.ac.uk/efo/EFO_1000786 GCST005572 Genome-wide genotyping array 12456 2018-05-11 29436472 Casalone E 2018-02-07 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/29436472 A novel variant in GLIS3 is associated with osteoarthritis. Osteoarthritis of the knee (with total joint replacement) 2,188 European ancestry cases, 9,939 European ancestry healthy controls 2,281 European ancestry cases, 9,194 European ancestry healthy controls Illumina [270934] 5 osteoarthritis, knee http://www.ebi.ac.uk/efo/EFO_0004616 GCST005574 Genome-wide genotyping array 12127 2017-11-29 29064910 Kure Fischer E 2017-10-23 Int Clin Psychopharmacol www.ncbi.nlm.nih.gov/pubmed/29064910 A molecular pathway analysis informs the genetic risk for arrhythmias during antipsychotic treatment. Antipsychotic drug-induced QTc interval change in schizophrenia 434 European ancestry individuals, 202 African ancestry individuals, 25 individuals NA Affymetrix, Perlegen [1785543] (imputed) 34 heart rate variability measurement, response to antipsychotic drug http://www.ebi.ac.uk/efo/EFO_0008003, http://purl.obolibrary.org/obo/GO_0097332 GCST004987 Genome-wide genotyping array 661 2018-11-30 29130521 Christopher L 2017-11-11 Ann Neurol www.ncbi.nlm.nih.gov/pubmed/29130521 A variant in PPP4R3A protects against alzheimer-related metabolic decline. Decline in glucose metabolism in posterior cingulate cortex 335 European ancestry MCI cases, 79 European ancestry AD cases, 192 European ancestry controls NA Illumina [2820932] (imputed) 9 glucose metabolism decline measurement, cingulate cortex measurement http://www.ebi.ac.uk/efo/EFO_0009392, http://www.ebi.ac.uk/efo/EFO_0007738 GCST006632 Genome-wide genotyping array 606 2018-01-15 29170429 Hachiya T 2017-11-23 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29170429 Genome-wide meta-analysis in Japanese populations identifies novel variants at the TMC6-TMC8 and SIX3-SIX2 loci associated with HbA1c. Glycated hemoglobin levels 7,704 Japanese ancestry individuals NA Illumina [7135436] (imputed) 7 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST005145 Genome-wide genotyping array 7704 2019-10-30 26160806 Proust C 2015-08-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/26160806 Contribution of Rare and Common Genetic Variants to Plasma Lipid Levels and Carotid Stiffness and Geometry: A Substudy of the Paris Prospective Study 3. Carotid artery external diameter 3,681 individuals NA Illumina [101597] 1 carotid artery external diameter measurement http://www.ebi.ac.uk/efo/EFO_0007719 GCST008979 Exome genotyping array [Exome array] 3681 2019-10-30 26160806 Proust C 2015-08-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/26160806 Contribution of Rare and Common Genetic Variants to Plasma Lipid Levels and Carotid Stiffness and Geometry: A Substudy of the Paris Prospective Study 3. Carotid artery internal diameter 3,681 individuals NA Illumina [101597] 1 carotid artery internal diameter measurement http://www.ebi.ac.uk/efo/EFO_0007720 GCST008982 Targeted genotyping array [Exome array] 3681 2019-10-30 26160806 Proust C 2015-08-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/26160806 Contribution of Rare and Common Genetic Variants to Plasma Lipid Levels and Carotid Stiffness and Geometry: A Substudy of the Paris Prospective Study 3. LDL cholesterol 3,681 individuals NA Illumina [101597] 5 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST008988 Exome genotyping array [Exome array] 3681 2019-10-30 26160806 Proust C 2015-08-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/26160806 Contribution of Rare and Common Genetic Variants to Plasma Lipid Levels and Carotid Stiffness and Geometry: A Substudy of the Paris Prospective Study 3. Triglycerides 3,681 individuals NA Illumina [101597] 8 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST008985 Targeted genotyping array [Exome array] 3681 2019-10-30 26160806 Proust C 2015-08-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/26160806 Contribution of Rare and Common Genetic Variants to Plasma Lipid Levels and Carotid Stiffness and Geometry: A Substudy of the Paris Prospective Study 3. Carotid artery stiffness 3,681 individuals NA Illumina [101597] 0 carotid artery stiffness measurement http://www.ebi.ac.uk/efo/EFO_0007718 GCST008981 Targeted genotyping array [Exome array] 3681 2019-10-30 26160806 Proust C 2015-08-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/26160806 Contribution of Rare and Common Genetic Variants to Plasma Lipid Levels and Carotid Stiffness and Geometry: A Substudy of the Paris Prospective Study 3. Carotid artery intima media thickness 3,681 individuals NA Illumina [101597] 0 carotid artery intima media thickness http://www.ebi.ac.uk/efo/EFO_0007117 GCST008989 Exome genotyping array [Exome array] 3681 2019-10-30 26160806 Proust C 2015-08-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/26160806 Contribution of Rare and Common Genetic Variants to Plasma Lipid Levels and Carotid Stiffness and Geometry: A Substudy of the Paris Prospective Study 3. Carotid artery mean blood pressure 3,681 individuals NA Illumina [101597] 0 carotid artery mean blood pressure measurement http://www.ebi.ac.uk/efo/EFO_0007723 GCST008986 Exome genotyping array [Exome array] 3681 2019-10-30 26160806 Proust C 2015-08-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/26160806 Contribution of Rare and Common Genetic Variants to Plasma Lipid Levels and Carotid Stiffness and Geometry: A Substudy of the Paris Prospective Study 3. HDL cholesterol 3,681 individuals NA Illumina [101597] 6 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST008987 Exome genotyping array [Exome array] 3681 2019-10-30 26160806 Proust C 2015-08-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/26160806 Contribution of Rare and Common Genetic Variants to Plasma Lipid Levels and Carotid Stiffness and Geometry: A Substudy of the Paris Prospective Study 3. Carotid artery central pulse pressure 3,681 individuals NA Illumina [101597] 0 carotid artery central pulse pressure measurement http://www.ebi.ac.uk/efo/EFO_0007721 GCST008980 Targeted genotyping array [Illumina HumanExome-12v1.1 BeadChip] 3681 2019-10-30 26160806 Proust C 2015-08-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/26160806 Contribution of Rare and Common Genetic Variants to Plasma Lipid Levels and Carotid Stiffness and Geometry: A Substudy of the Paris Prospective Study 3. Carotid artery circumferential wall stress 3,681 individuals NA Illumina [101597] 0 carotid artery circumferential wall stress measurement http://www.ebi.ac.uk/efo/EFO_0007724 GCST008983 Targeted genotyping array [Exome array] 3681 2019-10-30 26160806 Proust C 2015-08-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/26160806 Contribution of Rare and Common Genetic Variants to Plasma Lipid Levels and Carotid Stiffness and Geometry: A Substudy of the Paris Prospective Study 3. Carotid artery wall cross sectional area 3,681 individuals NA Illumina [101597] 0 carotid artery wall cross sectional area measurement http://www.ebi.ac.uk/efo/EFO_0007722 GCST008984 Targeted genotyping array [Exome array] 3681 2018-05-18 29514873 Mychaleckyj JC 2018-03-07 J Med Genet www.ncbi.nlm.nih.gov/pubmed/29514873 Multiplex genomewide association analysis of breast milk fatty acid composition extends the phenotypic association and potential selection of FADS1 variants to arachidonic acid, a critical infant micronutrient. Breast milk fatty acid composition (maternal genotype effect) 1,142 Bangladeshi ancestry (non-array genotyped, whole-genome imputed) mothers NA Illumina [~ 932000] (imputed) 10 fatty acid measurement, breast milk measurement, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0005110, http://www.ebi.ac.uk/efo/EFO_0009092, http://www.ebi.ac.uk/efo/EFO_0005939 GCST005586 Genome-wide genotyping array 1142 2018-05-18 29514873 Mychaleckyj JC 2018-03-07 J Med Genet www.ncbi.nlm.nih.gov/pubmed/29514873 Multiplex genomewide association analysis of breast milk fatty acid composition extends the phenotypic association and potential selection of FADS1 variants to arachidonic acid, a critical infant micronutrient. Breast milk fatty acid composition (infant genotype effect) 1,142 Bangladeshi ancestry infants NA Illumina [~ 932000] 8 fatty acid measurement, fetal genotype effect measurement, breast milk measurement http://www.ebi.ac.uk/efo/EFO_0005110, http://www.ebi.ac.uk/efo/EFO_0007959, http://www.ebi.ac.uk/efo/EFO_0009092 GCST005587 Genome-wide genotyping array 1142 2018-08-21 29518117 Lee HS 2018-03-08 PLoS One www.ncbi.nlm.nih.gov/pubmed/29518117 Nuclear receptor and VEGF pathways for gene-blood lead interactions, on bone mineral density, in Korean smokers. Bone mineral density x blood lead interaction in current smokers (2df test) 119 Korean ancestry current smokers NA Affymetrix [344396] 3 blood lead measurement, bone density http://www.ebi.ac.uk/efo/EFO_0007040, http://www.ebi.ac.uk/efo/EFO_0003923 GCST006133 Genome-wide genotyping array 119 2018-08-21 29518117 Lee HS 2018-03-08 PLoS One www.ncbi.nlm.nih.gov/pubmed/29518117 Nuclear receptor and VEGF pathways for gene-blood lead interactions, on bone mineral density, in Korean smokers. Bone mineral density x blood lead interaction in current smokers (1df test) 119 Korean ancestry current smokers NA Affymetrix [344396] 1 blood lead measurement, bone density http://www.ebi.ac.uk/efo/EFO_0007040, http://www.ebi.ac.uk/efo/EFO_0003923 GCST006132 Genome-wide genotyping array 119 2018-05-11 29523524 Singh S 2018-03-09 J Am Heart Assoc www.ncbi.nlm.nih.gov/pubmed/29523524 Genome Wide Association Study Identifies the HMGCS2 Locus to be Associated With Chlorthalidone Induced Glucose Increase in Hypertensive Patients. Change in glucose in response to thiazide diuretic treatment in hypertension 135 African American individuals, 175 European ancestry individuals 140 African American individuals, 222 European ancestry individuals Illumina [at least 2500000] (imputed) 6 response to thiazide, glucose measurement http://www.ebi.ac.uk/efo/EFO_0007981, http://www.ebi.ac.uk/efo/EFO_0004468 GCST005577 Genome-wide genotyping array 310 2018-03-29 29394082 Burkart KM 2018-02-02 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/29394082 A Genome-wide Association Study in Hispanics/Latinos Identifies Novel Signals for Lung Function. The Hispanic Community Health Study/Study of Latinos. FEV1 11,822 Hispanic individuals up to 4,162 Hispanic individuals, up to 876 African American individuals, up to 94,612 European ancestry individuals Illumina [27887661] (imputed) 0 forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0004314 GCST005418 Genome-wide genotyping array 11822 2018-03-29 29394082 Burkart KM 2018-02-02 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/29394082 A Genome-wide Association Study in Hispanics/Latinos Identifies Novel Signals for Lung Function. The Hispanic Community Health Study/Study of Latinos. Lung function (FEV1/FVC) 11,822 Hispanic individuals up to 4,162 Hispanic individuals, up to 876 African American individuals, up to 94,612 European ancestry individuals Illumina [2232944] (imputed) 3 FEV/FEC ratio http://www.ebi.ac.uk/efo/EFO_0004713 GCST005419 Genome-wide genotyping array 11822 2018-03-29 29394082 Burkart KM 2018-02-02 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/29394082 A Genome-wide Association Study in Hispanics/Latinos Identifies Novel Signals for Lung Function. The Hispanic Community Health Study/Study of Latinos. Airflow obstruction 854 Hispanic cases, 9,549 Hispanic controls European ancestry individuals (see Wilk et al 2012) Illumina [up to 27887661] (imputed) 1 pulmonary function measurement http://www.ebi.ac.uk/efo/EFO_0003892 GCST005416 Genome-wide genotyping array 10403 2018-03-29 29394082 Burkart KM 2018-02-02 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/29394082 A Genome-wide Association Study in Hispanics/Latinos Identifies Novel Signals for Lung Function. The Hispanic Community Health Study/Study of Latinos. Chronic obstructive pulmonary disease 363 Hispanic cases, 5,253 Hispanic controls European ancestry cases and controls (see Wilk et al 2012) Illumina [up to 27887661] (imputed) 2 chronic obstructive pulmonary disease http://www.ebi.ac.uk/efo/EFO_0000341 GCST005417 Genome-wide genotyping array 5616 2018-07-05 29572449 Gurung RL 2018-03-23 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29572449 Genetic markers for urine haptoglobin is associated with decline in renal function in type 2 diabetes in East Asians. Urinary haptoglobin levels in type 2 diabetes 236 Chinese ancestry individuals 512 Chinese ancestry individuals, 57 Malay ancestry individuals Illumina [781779] 1 haptoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004640 GCST005807 Genome-wide genotyping array 236 2018-07-05 29572449 Gurung RL 2018-03-23 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29572449 Genetic markers for urine haptoglobin is associated with decline in renal function in type 2 diabetes in East Asians. Plasma haptoglobin levels in type 2 diabetes 236 Chinese ancestry individuals 57 Malay ancestry individuals Illumina [781779] 1 haptoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004640 GCST005808 Genome-wide genotyping array 236 2018-06-05 29563342 Li XS 2018-03-22 JCI Insight www.ncbi.nlm.nih.gov/pubmed/29563342 Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk. Plasma trimethyllysine levels 1,297 European ancestry individuals NA Affymetrix [9012028] (imputed) 6 trimethyllysine measurement http://www.ebi.ac.uk/efo/EFO_0009134 GCST005670 Genome-wide genotyping array 1297 2018-04-30 26268663 Nalls MA 2015-08-13 Mov Disord www.ncbi.nlm.nih.gov/pubmed/26268663 Baseline genetic associations in the Parkinson's Progression Markers Initiative (PPMI). Parkinson's disease 367 European ancestry typical cases, 55 European ancestry atypical cases, 165 European ancestry controls NA Illumina [> 400000] 0 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST005548 Targeted genotyping array [ImmunoChip, NeuroX] 587 2018-05-02 29535370 Kleinstein SE 2018-02-28 Genes Immun www.ncbi.nlm.nih.gov/pubmed/29535370 Genome-wide association study (GWAS) of human host factors influencing viral severity of herpes simplex virus type 2 (HSV-2). Virologic severity in Herpes simplex virus type 2 infection 223 European ancestry individuals NA Illumina [1539908] 12 HSV2 virologic severity measurement http://www.ebi.ac.uk/efo/EFO_0009010 GCST005559 Genome-wide genotyping array 223 2018-06-22 29545823 O'Brien KM 2018-03-01 Front Genet www.ncbi.nlm.nih.gov/pubmed/29545823 Genome-Wide Association Study of Serum 25-Hydroxyvitamin D in US Women. Serum 25-Hydroxyvitamin D levels 1,576 European ancestry individuals, 134 African American individuals, 81 Hispanic individuals, 38 individuals 1,307 European ancestry individuals, 722 European breast cancer cases, 693 European ancestry controls, 120 African-American individuals, 38 African American breast cancer cases, 46 African American controls, 59 Hispanic individuals, 27 Hispanic breast cancer cases, 27 Hispanic controls, 47 individuals, 23 breast cancer cases, 14 controls Illumina [386449] 2 vitamin D measurement http://www.ebi.ac.uk/efo/EFO_0004631 GCST005729 Genome-wide genotyping array 1829 2018-11-09 29551738 Dong J 2018-03-15 Clin Gastroenterol Hepatol www.ncbi.nlm.nih.gov/pubmed/29551738 Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus. Esophageal adenocarcinoma x smoking interaction 2,284 European ancestry cases, 2,182 European ancestry controls NA Illumina [993501] 2 esophageal adenocarcinoma, smoking status measurement http://www.ebi.ac.uk/efo/EFO_0000478, http://www.ebi.ac.uk/efo/EFO_0006527 GCST006530 Genome-wide genotyping array 4466 2018-11-09 29551738 Dong J 2018-03-15 Clin Gastroenterol Hepatol www.ncbi.nlm.nih.gov/pubmed/29551738 Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus. Esophageal adenocarcinoma x pack-years of smoking exposure interaction 2,284 European ancestry cases, 2,182 European ancestry controls NA Illumina [993501] 1 esophageal adenocarcinoma, pack-years measurement http://www.ebi.ac.uk/efo/EFO_0000478, http://www.ebi.ac.uk/efo/EFO_0006526 GCST006532 Genome-wide genotyping array 4466 2018-11-09 29551738 Dong J 2018-03-15 Clin Gastroenterol Hepatol www.ncbi.nlm.nih.gov/pubmed/29551738 Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus. Esophageal adenocarcinoma x gastroesophageal reflux disease interaction 2,284 European ancestry cases, 2,182 European ancestry controls NA Illumina [993501] 3 esophageal adenocarcinoma, gastroesophageal reflux disease http://www.ebi.ac.uk/efo/EFO_0000478, http://www.ebi.ac.uk/efo/EFO_0003948 GCST006531 Genome-wide genotyping array 4466 2018-11-09 29551738 Dong J 2018-03-15 Clin Gastroenterol Hepatol www.ncbi.nlm.nih.gov/pubmed/29551738 Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus. Barrett's esophagus x BMI interaction 3,104 European ancestry cases, 2,182 European ancestry controls NA Illumina [993501] 1 Barrett's esophagus, body mass index http://www.ebi.ac.uk/efo/EFO_0000280, http://www.ebi.ac.uk/efo/EFO_0004340 GCST006529 Genome-wide genotyping array 5286 2018-11-09 29551738 Dong J 2018-03-15 Clin Gastroenterol Hepatol www.ncbi.nlm.nih.gov/pubmed/29551738 Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus. Barrett's esophagus x pack-years of smoking exposure interaction 3,104 European ancestry cases, 2,182 European ancestry controls NA Illumina [993501] 4 pack-years measurement, Barrett's esophagus http://www.ebi.ac.uk/efo/EFO_0006526, http://www.ebi.ac.uk/efo/EFO_0000280 GCST006528 Genome-wide genotyping array 5286 2018-11-09 29551738 Dong J 2018-03-15 Clin Gastroenterol Hepatol www.ncbi.nlm.nih.gov/pubmed/29551738 Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus. Barrett's esophagus x smoking interaction 3,104 European ancestry cases, 2,182 European ancestry controls NA Illumina [993501] 0 smoking status measurement, Barrett's esophagus http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0000280 GCST006527 Genome-wide genotyping array 5286 2018-11-09 29551738 Dong J 2018-03-15 Clin Gastroenterol Hepatol www.ncbi.nlm.nih.gov/pubmed/29551738 Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus. Barrett's esophagus x gastroesophageal reflux disease interaction 3,104 European ancestry cases, 2,182 European ancestry controls NA Illumina [993501] 0 Barrett's esophagus, gastroesophageal reflux disease http://www.ebi.ac.uk/efo/EFO_0000280, http://www.ebi.ac.uk/efo/EFO_0003948 GCST006526 Genome-wide genotyping array 5286 2018-11-09 29551738 Dong J 2018-03-15 Clin Gastroenterol Hepatol www.ncbi.nlm.nih.gov/pubmed/29551738 Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus. Esophageal adenocarcinoma x BMI interaction 2,284 European ancestry cases, 2,182 European ancestry controls NA Illumina [993501] 0 esophageal adenocarcinoma, body mass index http://www.ebi.ac.uk/efo/EFO_0000478, http://www.ebi.ac.uk/efo/EFO_0004340 GCST006525 Genome-wide genotyping array 4466 2019-03-28 30631343 Rolfe S 2018-12-18 Front Genet www.ncbi.nlm.nih.gov/pubmed/30631343 Associations Between Genetic Data and Quantitative Assessment of Normal Facial Asymmetry. Normal facial asymmetry (angle of surface orientation score) 3,186 European ancestry individuals NA Illumina [747780] 21 facial asymmetry measurement http://www.ebi.ac.uk/efo/EFO_0009751 GCST007448 Genome-wide genotyping array 3186 2019-03-28 30631343 Rolfe S 2018-12-18 Front Genet www.ncbi.nlm.nih.gov/pubmed/30631343 Associations Between Genetic Data and Quantitative Assessment of Normal Facial Asymmetry. Normal facial asymmetry (angle of deformation score) 3,186 European ancestry individuals NA Illumina [747780] 4 facial asymmetry measurement http://www.ebi.ac.uk/efo/EFO_0009751 GCST007449 Genome-wide genotyping array 3186 2019-03-28 30631343 Rolfe S 2018-12-18 Front Genet www.ncbi.nlm.nih.gov/pubmed/30631343 Associations Between Genetic Data and Quantitative Assessment of Normal Facial Asymmetry. Normal facial asymmetry (deformation magnitude) 3,186 European ancestry individuals NA Illumina [747780] 5 facial asymmetry measurement http://www.ebi.ac.uk/efo/EFO_0009751 GCST007450 Genome-wide genotyping array 3186 2019-02-11 30012220 Prins BP 2018-07-17 Genome Biol www.ncbi.nlm.nih.gov/pubmed/30012220 Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6. QRS duration up to 77,898 European ancestry individuals, up to 7,695 African American individuals up to 111,874 European ancestry individuals Illumina [162199] 28 QRS duration http://www.ebi.ac.uk/efo/EFO_0005055 GCST007104 Exome genotyping array [Exome array] 85593 2019-02-11 30012220 Prins BP 2018-07-17 Genome Biol www.ncbi.nlm.nih.gov/pubmed/30012220 Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6. QRS duration 77,898 European ancestry individuals NA Illumina [213295] 28 QRS duration http://www.ebi.ac.uk/efo/EFO_0005055 GCST007103 Exome genotyping array [Exome array] 77898 2019-02-11 30012220 Prins BP 2018-07-17 Genome Biol www.ncbi.nlm.nih.gov/pubmed/30012220 Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6. QRS duration 7,695 African American individuals NA Illumina [164799] 1 QRS duration http://www.ebi.ac.uk/efo/EFO_0005055 GCST007105 Exome genotyping array [Exome array] 7695 2019-02-01 30621171 Coltell O 2019-01-04 Nutrients www.ncbi.nlm.nih.gov/pubmed/30621171 Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population. Serum bilirubin levels in metabolic syndrome 188 European ancestry male individuals, 242 European ancestry female individuals NA Illumina [622468] 23 bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004570 GCST007018 Genome-wide genotyping array 430 2019-02-01 30621171 Coltell O 2019-01-04 Nutrients www.ncbi.nlm.nih.gov/pubmed/30621171 Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population. Serum bilirubin levels x sex interaction in metabolic syndrome 188 European ancestry male individuals, 242 European ancestry female individuals NA Illumina [622468] 16 sex interaction measurement, bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0004570 GCST007016 Genome-wide genotyping array 430 2019-02-01 30621171 Coltell O 2019-01-04 Nutrients www.ncbi.nlm.nih.gov/pubmed/30621171 Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population. Serum bilirubin levels x Mediterranean diet adherence interaction in metabolic syndrome 257 European ancestry individuals with low adherence to Mediterranean diet, 161 European ancestry individuals with high adherence to Mediterranean diet NA Illumina [622468] 26 diet measurement, bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0008111, http://www.ebi.ac.uk/efo/EFO_0004570 GCST007017 Genome-wide genotyping array 418 2019-08-15 26534935 Weng L 2015-11-03 Physiol Genomics www.ncbi.nlm.nih.gov/pubmed/26534935 Genetic loci associated with nonobstructive coronary artery disease in Caucasian women. Nonobstructive coronary artery disease 332 European ancestry female cases, 1,003 European ancestry female controls NA Illumina [52371] 5 non-obstructive coronary artery disease http://www.ebi.ac.uk/efo/EFO_1001483 GCST008436 Targeted genotyping array [Cardio-MetaboChip] 1335 2017-01-27 27523435 Mosteller M 2016-07-05 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/27523435 No evidence of large genetic effects on steroid response in asthma patients. Response to inhaled corticosteroid treatment in asthma (change in FEV1) 2,672 cases NA Illumina [~ 9800000] (imputed) 0 FEV change measurement, response to corticosteroid http://www.ebi.ac.uk/efo/EFO_0005921, http://purl.obolibrary.org/obo/GO_0031960 GCST003567 Genome-wide genotyping array 2672 2016-09-28 26542096 Marenholz I 2015-11-06 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26542096 Meta-analysis identifies seven susceptibility loci involved in the atopic march. Atopic march 1,151 European ancestry early-onset eczema and childhood asthma cases, 10,030 European ancestry controls 1,277 European ancestry early-onset eczema and childhood asthma cases, 7,004 European ancestry controls Affymetrix, Illumina [1633153] (imputed) 7 childhood onset asthma, atopic eczema, atopic march http://www.ebi.ac.uk/efo/EFO_0004591, http://www.ebi.ac.uk/efo/EFO_0000274, http://www.ebi.ac.uk/efo/EFO_0007755 GCST003180 Genome-wide genotyping array 11181 2017-04-10 28039263 Wheeler HE 2016-12-30 Clin Cancer Res www.ncbi.nlm.nih.gov/pubmed/28039263 Variants in WFS1 and Other Mendelian Deafness Genes Are Associated with Cisplatin-Associated Ototoxicity. Cisplatin-induced ototoxicity 511 European ancestry testicular cancer survivor individuals 238 children Illumina [5060354] (imputed) 20 ototoxicity, response to cisplatin http://www.ebi.ac.uk/efo/EFO_0006951, http://purl.obolibrary.org/obo/GO_0072718 GCST003898 Genome-wide genotyping array 511 2017-04-11 28040410 Meyers JL 2016-12-28 Int J Psychophysiol www.ncbi.nlm.nih.gov/pubmed/28040410 A genome wide association study of fast beta EEG in families of European ancestry. Fast beta electroencephalogram 1,564 European ancestry individuals from 117 alcohol dependence affected families NA Illumina [12973748] (imputed) 5 alcohol dependence measurement, electroencephalogram measurement http://www.ebi.ac.uk/efo/EFO_0007835, http://www.ebi.ac.uk/efo/EFO_0004357 GCST003902 Genome-wide genotyping array 1681 2017-03-24 27770636 Mez J 2016-10-20 Alzheimers Dement www.ncbi.nlm.nih.gov/pubmed/27770636 Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans. Late-onset Alzheimer's disease 1,825 African American ancestry cases, 3,784 African American ancestry controls NA NR [19725427] (imputed) 123 late-onset Alzheimers disease http://www.ebi.ac.uk/efo/EFO_1001870 GCST003815 Genome-wide genotyping array 5609 2017-06-08 28062665 Kawashima M 2017-01-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28062665 Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population. Primary biliary cholangitis 1,381 Japanese ancestry cases, 1,505 Japanese ancestry controls 512 Japanese ancestry cases, 6,512 Japanese ancestry controls Affymetrix [425290] 9 primary biliary cirrhosis http://www.ebi.ac.uk/efo/EFO_1001486 GCST004145 Genome-wide genotyping array 2886 2017-03-17 27702942 Tang CS 2016-10-03 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/27702942 Trans-ethnic meta-analysis of genome-wide association studies for Hirschsprung disease. Hirschsprung disease 212 European ancestry cases, 173 Chinese ancestry cases, 122 Korean ancestry cases, 202 European ancestry controls, 615 Chinese ancestry controls, 374 Korean ancestry controls NA Affymetrix, Illumina [at least 6512116] (imputed) 7 Hirschsprung disease http://www.orpha.net/ORDO/Orphanet_388 GCST003764 Genome-wide genotyping array 1698 2019-09-20 26278503 Huang C 2015-11-01 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/26278503 Characterization of genetic loci that affect susceptibility to inflammatory bowel diseases in African Americans. Inflammatory bowel disease 1,511 African American cases, 1,797 African American controls NA Illumina [130241] 3 inflammatory bowel disease http://www.ebi.ac.uk/efo/EFO_0003767 GCST008731 Targeted genotyping array [Immunochip] 3308 2019-09-20 26278503 Huang C 2015-11-01 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/26278503 Characterization of genetic loci that affect susceptibility to inflammatory bowel diseases in African Americans. Crohn's disease 1,088 African American cases, 1,797 African American controls NA Illumina [130241] 1 Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000384 GCST008730 Targeted genotyping array [ImmunoChip] 2885 2019-09-20 26278503 Huang C 2015-11-01 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/26278503 Characterization of genetic loci that affect susceptibility to inflammatory bowel diseases in African Americans. Ulcerative colitis 361 African American cases, 1,797 African American controls NA Illumina [130241] 2 ulcerative colitis http://www.ebi.ac.uk/efo/EFO_0000729 GCST008732 Targeted genotyping array [Immunochip] 2158 2017-09-22 28836065 Hellwege JN 2017-08-23 Hum Genet www.ncbi.nlm.nih.gov/pubmed/28836065 A multi-stage genome-wide association study of uterine fibroids in African Americans. Uterine fibroids 3,999 African American cases, 4,764 African American controls NA Affymetrix, Illumina [17963051] (imputed) 4 uterine fibroid http://www.ebi.ac.uk/efo/EFO_0000731 GCST004779 Genome-wide genotyping array 8763 2017-12-01 29065906 Joo YB 2017-10-25 Arthritis Res Ther www.ncbi.nlm.nih.gov/pubmed/29065906 Biological function integrated prediction of severe radiographic progression in rheumatoid arthritis: a nested case control study. Severe progression in rheumatoid arthritis 120 Korean ancestry cases, 118 Korean ancestry controls NA Illumina [1343748] 2 rheumatoid arthritis, disease progression measurement http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0008336 GCST004998 Genome-wide genotyping array 238 2017-12-20 29147026 Chen CH 2017-11-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29147026 Leveraging genome characteristics to improve gene discovery for putamen subcortical brain structure. Putamen volume 12,596 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 10 putamen volume http://www.ebi.ac.uk/efo/EFO_0006932 GCST005083 Genome-wide genotyping array 12596 2019-09-10 26498133 Arya R 2015-08-26 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/26498133 Genetic Variants Influencing Joint Damage in Mexican Americans and European Americans With Rheumatoid Arthritis. Joint damage in rheumatoid arthritis 666 Mexican ancestry cases, 407 European ancestry cases NA Illumina [at least 127563] (imputed) 2 joint damage measurement http://www.ebi.ac.uk/efo/EFO_0005413 GCST008643 Targeted genotyping array [ImmunoChip] 1073 2017-01-27 27159506 Dunn EC 2016-05-09 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/27159506 Genome-wide association study of generalized anxiety symptoms in the Hispanic Community Health Study/Study of Latinos. Anxiety 12,282 Hispanic ancestry individuals 8,195 Hispanic ancestry individuals Illumina [25568744] (imputed) 0 anxiety disorder measurement http://www.ebi.ac.uk/efo/EFO_0007795 GCST003562 Genome-wide genotyping array 12282 2017-04-01 27723779 Gong J 2016-10-10 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/27723779 Genome-Wide Interaction Analyses between Genetic Variants and Alcohol Consumption and Smoking for Risk of Colorectal Cancer. Colorectal cancer (alcohol consumption interaction) 8,058 European ancestry non/occasional, light-to-moderate, and heavy drinker cases, 8,765 European ancestry non/occasional, light-to-moderate, and heavy drinker controls NA Affymetrix, Illumina [~ 2700000] (imputed) 2 colorectal cancer, alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0005842, http://www.ebi.ac.uk/efo/EFO_0007878 GCST003873 Genome-wide genotyping array 16823 2017-04-01 27723779 Gong J 2016-10-10 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/27723779 Genome-Wide Interaction Analyses between Genetic Variants and Alcohol Consumption and Smoking for Risk of Colorectal Cancer. Colorectal cancer (smoking interaction) 11,219 European ancestry ever-smoker and never-smoker cases, 11,382 European ancestry ever-smoker and never-smoker controls NA Affymetrix, Illumina [~ 2700000] (imputed) 0 smoking status measurement, colorectal cancer http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0005842 GCST003874 Genome-wide genotyping array 22601 2017-03-17 27764096 Hoffmann TJ 2016-10-20 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/27764096 A Large Genome-Wide Association Study of Age-Related Hearing Impairment Using Electronic Health Records. Age-related hearing impairment 6,527 European ancestry cases, 45,882 European ancestry controls 481 Latino cases, 398 East Asian ancestry cases, 146 African American cases, 5,215 Latino controls, 5,040 East Asian ancestry controls, 2,133 African American controls Affymetrix [9469183] (imputed) 3 age-related hearing impairment http://www.ebi.ac.uk/efo/EFO_0005782 GCST003763 Genome-wide genotyping array 52409 2018-05-02 29511194 Helgadottir A 2018-03-07 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29511194 Genome-wide analysis yields new loci associating with aortic valve stenosis. Aortic valve stenosis 2,457 Icelandic ancestry cases, 349,342 Icelandic ancestry controls (including non-array genotyped, whole genome imputed individuals) 4,850 European ancestry cases, 451,731 European ancestry controls Illumina [32500000] (imputed) 5 aortic stenosis http://www.ebi.ac.uk/efo/EFO_0000266 GCST005561 Genome-wide genotyping array, Genome-wide sequencing 351799 2018-07-02 29511167 Theriault S 2018-03-07 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29511167 A transcriptome-wide association study identifies PALMD as a susceptibility gene for calcific aortic valve stenosis. Calcific aortic valve stenosis 1,009 French Canadian cases, 1,017 French Canadian controls 1,391 European ancestry cases, 352,195 European ancestry controls Illumina [7732680] (imputed) 1 aortic stenosis, aortic valve calcification http://www.ebi.ac.uk/efo/EFO_0000266, http://www.ebi.ac.uk/efo/EFO_0005239 GCST005785 Genome-wide genotyping array 2026 2018-09-06 29923122 Kakuta Y 2018-06-19 J Gastroenterol www.ncbi.nlm.nih.gov/pubmed/29923122 NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. Thiopurine-induced severe leukopenia in inflammatory bowel disease (conditioned on rs116855232) 72 Japanese ancestry cases, 1,148 Japanese ancestry controls NA Affymetrix [> 5000000] (imputed) 0 leukopenia, response to thiopurine http://www.ebi.ac.uk/efo/EFO_0004233, http://www.ebi.ac.uk/efo/EFO_0006317 GCST006200 Genome-wide genotyping array 1220 2018-09-06 29923122 Kakuta Y 2018-06-19 J Gastroenterol www.ncbi.nlm.nih.gov/pubmed/29923122 NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. Thiopurine-induced leukopenia in inflammatory bowel disease 196 Japanese ancestry cases, 1,024 Japanese ancestry controls NA Affymetrix [> 5000000] (imputed) 2 leukopenia, response to thiopurine http://www.ebi.ac.uk/efo/EFO_0004233, http://www.ebi.ac.uk/efo/EFO_0006317 GCST006201 Genome-wide genotyping array 1220 2018-09-06 29923122 Kakuta Y 2018-06-19 J Gastroenterol www.ncbi.nlm.nih.gov/pubmed/29923122 NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. Thiopurine-induced leukopenia in inflammatory bowel disease (conditioned on rs116855232) 196 Japanese ancestry cases, 1,024 Japanese ancestry controls NA Affymetrix [> 5000000] (imputed) 1 leukopenia, response to thiopurine http://www.ebi.ac.uk/efo/EFO_0004233, http://www.ebi.ac.uk/efo/EFO_0006317 GCST006202 Genome-wide genotyping array 1220 2018-09-06 29923122 Kakuta Y 2018-06-19 J Gastroenterol www.ncbi.nlm.nih.gov/pubmed/29923122 NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. Thiopurine-induced severe leukopenia in inflammatory bowel disease 72 Japanese ancestry cases, 1,148 Japanese ancestry controls NA Affymetrix [> 5000000] (imputed) 1 leukopenia, response to thiopurine http://www.ebi.ac.uk/efo/EFO_0004233, http://www.ebi.ac.uk/efo/EFO_0006317 GCST006204 Genome-wide genotyping array 1220 2018-09-06 29923122 Kakuta Y 2018-06-19 J Gastroenterol www.ncbi.nlm.nih.gov/pubmed/29923122 NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. Thiopurine-induced acute severe leukopenia in inflammatory bowel disease 43 Japanese ancestry cases, 1,172 Japanese ancestry controls NA Affymetrix [> 5000000] (imputed) 1 leukopenia, response to thiopurine http://www.ebi.ac.uk/efo/EFO_0004233, http://www.ebi.ac.uk/efo/EFO_0006317 GCST006205 Genome-wide genotyping array 1215 2018-09-06 29923122 Kakuta Y 2018-06-19 J Gastroenterol www.ncbi.nlm.nih.gov/pubmed/29923122 NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. Thiopurine-induced alopecia in inflammatory bowel disease 81 Japanese ancestry cases, 1,139 Japanese ancestry controls NA Affymetrix [> 5000000] (imputed) 5 Alopecia, response to thiopurine http://www.orpha.net/ORDO/Orphanet_79364, http://www.ebi.ac.uk/efo/EFO_0006317 GCST006206 Genome-wide genotyping array 1220 2018-09-06 29923122 Kakuta Y 2018-06-19 J Gastroenterol www.ncbi.nlm.nih.gov/pubmed/29923122 NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. Thiopurine-induced severe alopecia in inflammatory bowel disease 41 Japanese ancestry cases, 1,179 Japanese ancestry controls NA Affymetrix [> 5000000] (imputed) 1 Alopecia, response to thiopurine http://www.orpha.net/ORDO/Orphanet_79364, http://www.ebi.ac.uk/efo/EFO_0006317 GCST006207 Genome-wide genotyping array 1220 2018-09-06 29923122 Kakuta Y 2018-06-19 J Gastroenterol www.ncbi.nlm.nih.gov/pubmed/29923122 NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. Thiopurine-induced pancreatitis in inflammatory bowel disease 18 Japanese ancestry cases, 1,202 Japanese ancestry controls NA Affymetrix [> 5000000] (imputed) 2 pancreatitis, response to thiopurine http://www.ebi.ac.uk/efo/EFO_0000278, http://www.ebi.ac.uk/efo/EFO_0006317 GCST006208 Genome-wide genotyping array 1220 2018-09-06 29923122 Kakuta Y 2018-06-19 J Gastroenterol www.ncbi.nlm.nih.gov/pubmed/29923122 NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. Thiopurine-induced fever in inflammatory bowel disease 10 Japanese ancestry cases, 1,210 Japanese ancestry controls NA Affymetrix [> 5000000] (imputed) 0 Fever, response to thiopurine http://purl.obolibrary.org/obo/HP_0001945, http://www.ebi.ac.uk/efo/EFO_0006317 GCST006209 Genome-wide genotyping array 1220 2018-09-06 29923122 Kakuta Y 2018-06-19 J Gastroenterol www.ncbi.nlm.nih.gov/pubmed/29923122 NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. Thiopurine-induced digestive symptoms in inflammatory bowel disease 93 Japanese ancestry cases, 1,127 Japanese ancestry controls NA Affymetrix [> 5000000] (imputed) 1 digestive system disease, response to thiopurine http://www.ebi.ac.uk/efo/EFO_0000405, http://www.ebi.ac.uk/efo/EFO_0006317 GCST006210 Genome-wide genotyping array 1220 2018-09-06 29923122 Kakuta Y 2018-06-19 J Gastroenterol www.ncbi.nlm.nih.gov/pubmed/29923122 NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. Thiopurine-induced infection in inflammatory bowel disease 14 Japanese ancestry cases, 1,206 Japanese ancestry controls NA Affymetrix [> 5000000] (imputed) 0 response to thiopurine, susceptibility to infectious disease measurement http://www.ebi.ac.uk/efo/EFO_0006317, http://www.ebi.ac.uk/efo/EFO_0008422 GCST006211 Genome-wide genotyping array 1220 2018-09-06 29923122 Kakuta Y 2018-06-19 J Gastroenterol www.ncbi.nlm.nih.gov/pubmed/29923122 NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. Thiopurine-induced liver dysfunction in inflammatory bowel disease 39 Japanese ancestry cases, 1,181 Japanese ancestry controls NA Affymetrix [> 5000000] (imputed) 0 response to thiopurine, liver disease http://www.ebi.ac.uk/efo/EFO_0006317, http://www.ebi.ac.uk/efo/EFO_0001421 GCST006212 Genome-wide genotyping array 1220 2018-09-06 29923122 Kakuta Y 2018-06-19 J Gastroenterol www.ncbi.nlm.nih.gov/pubmed/29923122 NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. Thiopurine-induced skin symptoms in inflammatory bowel disease 6 Japanese ancestry cases, 1,214 Japanese ancestry controls NA Affymetrix [> 5000000] (imputed) 0 skin disease, response to thiopurine http://www.ebi.ac.uk/efo/EFO_0000701, http://www.ebi.ac.uk/efo/EFO_0006317 GCST006213 Genome-wide genotyping array 1220 2018-09-06 29923122 Kakuta Y 2018-06-19 J Gastroenterol www.ncbi.nlm.nih.gov/pubmed/29923122 NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. Thiopurine-induced alopecia in inflammatory bowel disease (conditioned on rs116855232) 81 Japanese ancestry cases, 1,139 Japanese ancestry controls NA Affymetrix [> 5000000] (imputed) 0 Alopecia, response to thiopurine http://www.orpha.net/ORDO/Orphanet_79364, http://www.ebi.ac.uk/efo/EFO_0006317 GCST006214 Genome-wide genotyping array 1220 2018-09-06 29923122 Kakuta Y 2018-06-19 J Gastroenterol www.ncbi.nlm.nih.gov/pubmed/29923122 NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. Thiopurine-induced acute severe leukopenia in inflammatory bowel disease (conditioned on rs116855232) 43 Japanese ancestry cases, 1,172 Japanese ancestry controls NA Affymetrix [> 5000000] (imputed) 1 leukopenia, response to thiopurine http://www.ebi.ac.uk/efo/EFO_0004233, http://www.ebi.ac.uk/efo/EFO_0006317 GCST006215 Genome-wide genotyping array 1215 2018-09-06 29923122 Kakuta Y 2018-06-19 J Gastroenterol www.ncbi.nlm.nih.gov/pubmed/29923122 NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study. Thiopurine-induced severe alopecia in inflammatory bowel disease (conditioned on rs116855232) 41 Japanese ancestry cases, 1,179 Japanese ancestry controls NA Affymetrix [> 5000000] (imputed) 0 Alopecia, response to thiopurine http://www.orpha.net/ORDO/Orphanet_79364, http://www.ebi.ac.uk/efo/EFO_0006317 GCST006199 Genome-wide genotyping array 1220 2019-03-18 27089180 Day FR 2016-04-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27089180 Physical and neurobehavioral determinants of reproductive onset and success. Age at first birth 66,310 British ancestry females 117,626 European ancestry males, 144,471 European ancestry females Affymetrix [641018] (imputed) 4 age at first birth measurement http://www.ebi.ac.uk/efo/EFO_0009101 GCST007336 Genome-wide genotyping array 66310 2019-03-18 27089180 Day FR 2016-04-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27089180 Physical and neurobehavioral determinants of reproductive onset and success. Age at first sexual intercourse 59,357 British ancestry males, 66,310 British ancestry females NA Affymetrix [641018] (imputed) 36 age at first sexual intercourse measurement http://www.ebi.ac.uk/efo/EFO_0009749 GCST007335 Genome-wide genotyping array 125667 2018-06-27 29527006 Warrier V 2018-03-12 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/29527006 Genome-wide analyses of self-reported empathy: correlations with autism, schizophrenia, and anorexia nervosa. Empathy quotient 22,318 European ancestry males, 24,543 European ancestry females NA Illumina [9955952] (imputed) 11 empathy measurement http://www.ebi.ac.uk/efo/EFO_0009183 GCST005751 Genome-wide genotyping array 46861 2019-03-04 30626913 Amare AT 2019-01-09 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30626913 Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression. Broad depression or major depressive disorder (self-reported) 9,240 European ancestry broad depression cases, 9,519 European ancestry broad depression controls, 51,258 European ancestry individuals, 75,607 European ancestry self-reported major depressive disorder cases, 231,747 European ancestry self-reported major depressive disorder controls 322,580 individuals Affymetrix, Illumina [at least 918921] (imputed) 3 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST007254 Genome-wide genotyping array 377371 2019-03-04 30626913 Amare AT 2019-01-09 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30626913 Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression. Broad depression or major depressive disorder (recurrent) 9,240 European ancestry broad depression cases, 9,519 European ancestry broad depression controls, 51,258 European ancestry individuals, 5,303 Chinese ancestry recurrent major depressive disorder cases, 5,337 Chinese ancestry recurrent major depressive disorder controls 322,580 individuals Affymetrix, Illumina [at least 918921] (imputed) 1 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST007256 Genome-wide genotyping array 80657 2019-03-04 30626913 Amare AT 2019-01-09 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30626913 Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression. Broad depression or bipolar disorder 9,240 European ancestry broad depression cases, 9,519 European ancestry broad depression controls, 51,258 European ancestry individuals, 7,481 European ancestry bipolar disorder cases, 9,250 European ancestry bipolar disorder controls 322,580 individuals Affymetrix, Illumina [at least 918921] (imputed) 3 unipolar depression, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000289 GCST007255 Genome-wide genotyping array 86748 2019-03-04 30626913 Amare AT 2019-01-09 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30626913 Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression. Broad depression or schizophrenia 9,240 European ancestry broad depression cases, 9,519 European ancestry broad depression controls, 51,258 European ancestry individuals, 36,989 European and East Asian ancestry schizophrenia cases, 113,075 European and East Asian ancestry schizophrenia controls 322,580 individuals Affymetrix, Illumina [at least 918921] (imputed) 16 unipolar depression, schizophrenia http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692 GCST007257 Genome-wide genotyping array 220081 2019-04-18 30617275 Erzurumluoglu AM 2019-01-07 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30617275 Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci. Smoking initiation 324,851 European ancestry individuals, 21,962 South Asian ancestry individuals up to 275,596 European ancestry individuals Affymetrix, Illumina [up to 1207583] (imputed) 40 smoking initiation http://www.ebi.ac.uk/efo/EFO_0005670 GCST007603 Genome-wide genotyping array, Exome genotyping array 346813 2019-04-18 30617275 Erzurumluoglu AM 2019-01-07 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30617275 Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci. Smoking behaviour (cigarettes smoked per day) 128,746 European and South Asian ancestry individuals up to 275,596 European ancestry individuals Affymetrix, Illumina [up to 1207583] (imputed) 8 cigarettes per day measurement http://www.ebi.ac.uk/efo/EFO_0006525 GCST007602 Genome-wide genotyping array, Exome genotyping array 128746 2019-04-18 30617275 Erzurumluoglu AM 2019-01-07 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30617275 Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci. Smoking behaviour (cigarette pack-years) 131,892 European and South Asian ancestry individuals up to 275,596 European ancestry individuals Affymetrix, Illumina [up to 1207583] (imputed) 0 pack-years measurement http://www.ebi.ac.uk/efo/EFO_0006526 GCST007601 Genome-wide genotyping array, Exome genotyping array 131892 2019-04-18 30617275 Erzurumluoglu AM 2019-01-07 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30617275 Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci. Smoking cessation 121,543 European and South Asian ancestry individuals up to 275,596 European ancestry individuals Affymetrix, Illumina [up to 1207583] (imputed) 2 smoking cessation http://www.ebi.ac.uk/efo/EFO_0004319 GCST007604 Genome-wide genotyping array, Exome genotyping array 121543 2018-05-30 29535761 Haaland OA 2018-02-26 Front Genet www.ncbi.nlm.nih.gov/pubmed/29535761 A Genome-Wide Search for Gene-Environment Effects in Isolated Cleft Lip with or without Cleft Palate Triads Points to an Interaction between Maternal Periconceptional Vitamin Use and Variants in ESRRG. Cleft lip with or without cleft palate (maternal periconceptional vitamin use interaction) up to 825 European ancestry case-parent trios, up to 1,024 Asian ancestry case-parent trios, up to 59 case-parent trios NA Illumina [341191] 8 vitamin supplement exposure measurement, cleft lip http://www.ebi.ac.uk/efo/EFO_0009116, http://www.ebi.ac.uk/efo/EFO_0003959 GCST005652 Genome-wide genotyping array 1908 2018-05-30 29535761 Haaland OA 2018-02-26 Front Genet www.ncbi.nlm.nih.gov/pubmed/29535761 A Genome-Wide Search for Gene-Environment Effects in Isolated Cleft Lip with or without Cleft Palate Triads Points to an Interaction between Maternal Periconceptional Vitamin Use and Variants in ESRRG. Cleft lip with or without cleft palate (maternal periconceptional cigarette smoking interaction) up to 825 European ancestry case-parent trios, up to 1,024 Asian ancestry case-parent trios, up to 59 case-parent trios NA Illumina [341191] 1 tobacco smoke exposure measurement, cleft lip http://www.ebi.ac.uk/efo/EFO_0009115, http://www.ebi.ac.uk/efo/EFO_0003959 GCST005654 Genome-wide genotyping array 1908 2018-05-30 29535761 Haaland OA 2018-02-26 Front Genet www.ncbi.nlm.nih.gov/pubmed/29535761 A Genome-Wide Search for Gene-Environment Effects in Isolated Cleft Lip with or without Cleft Palate Triads Points to an Interaction between Maternal Periconceptional Vitamin Use and Variants in ESRRG. Cleft lip with or without cleft palate (maternal periconceptional alcohol intake interaction) up to 825 European ancestry case-parent trios, up to 1,024 Asian ancestry case-parent trios, up to 59 case-parent trios NA Illumina [341191] 2 cleft lip, alcohol exposure measurement http://www.ebi.ac.uk/efo/EFO_0003959, http://www.ebi.ac.uk/efo/EFO_0009113 GCST005653 Genome-wide genotyping array 1908 2018-09-20 29532581 Hallfors J 2018-03-13 Addict Biol www.ncbi.nlm.nih.gov/pubmed/29532581 Genome-wide association study in Finnish twins highlights the connection between nicotine addiction and neurotrophin signaling pathway. Smoking behaviour (cigarettes smoked per day) 1,715 Finnish ancestry ever smoker individuals from 739 families 7,344 Finnish ancestry ever smoker individuals Illumina [9469131] (imputed) 0 cigarettes per day measurement http://www.ebi.ac.uk/efo/EFO_0006525 GCST006299 Genome-wide genotyping array 2454 2018-09-20 29532581 Hallfors J 2018-03-13 Addict Biol www.ncbi.nlm.nih.gov/pubmed/29532581 Genome-wide association study in Finnish twins highlights the connection between nicotine addiction and neurotrophin signaling pathway. Smoking behaviour (maximum cigarettes in a 24 hour period) 1,711 Finnish ancestry ever smoker individuals from up to 739 families NA Illumina [9469131] (imputed) 12 maximum cigarettes per day measurement http://www.ebi.ac.uk/efo/EFO_0009264 GCST006300 Genome-wide genotyping array 2450 2018-09-20 29532581 Hallfors J 2018-03-13 Addict Biol www.ncbi.nlm.nih.gov/pubmed/29532581 Genome-wide association study in Finnish twins highlights the connection between nicotine addiction and neurotrophin signaling pathway. Nicotine dependence symptom count 1,715 Finnish ancestry ever smoker individuals from 739 families NA Illumina [9469131] (imputed) 35 nicotine dependence symptom count http://www.ebi.ac.uk/efo/EFO_0009262 GCST006301 Genome-wide genotyping array 2454 2018-09-20 29532581 Hallfors J 2018-03-13 Addict Biol www.ncbi.nlm.nih.gov/pubmed/29532581 Genome-wide association study in Finnish twins highlights the connection between nicotine addiction and neurotrophin signaling pathway. Nicotine dependence 873 Finnish ancestry cases and 842 Finnish ancestry controls from 739 families NA Illumina [9469131] (imputed) 16 nicotine dependence http://www.ebi.ac.uk/efo/EFO_0003768 GCST006302 Genome-wide genotyping array 2454 2018-09-20 29532581 Hallfors J 2018-03-13 Addict Biol www.ncbi.nlm.nih.gov/pubmed/29532581 Genome-wide association study in Finnish twins highlights the connection between nicotine addiction and neurotrophin signaling pathway. Nicotine withdrawal symptom count 1,703 Finnish ancestry ever smoker individuals from up to 739 families NA Illumina [9469131] (imputed) 25 nicotine withdrawal symptom count http://www.ebi.ac.uk/efo/EFO_0009263 GCST006303 Genome-wide genotyping array 2442 2019-01-11 29532581 Hallfors J 2018-03-13 Addict Biol www.ncbi.nlm.nih.gov/pubmed/29532581 Genome-wide association study in Finnish twins highlights the connection between nicotine addiction and neurotrophin signaling pathway. Nicotine withdrawal 540 Finnish ancestry cases and 1,163 Finnish ancestry controls from up to 739 families NA Illumina [9469131] (imputed) 18 nicotine withdrawal measurement http://www.ebi.ac.uk/efo/EFO_0009362 GCST006869 Genome-wide genotyping array 2442 2017-01-24 27519822 Power RA 2016-05-24 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/27519822 Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Major depressive disorder 3,869 European ancestry 50% oldest-onset cases, 5,051 European ancestry cases, 2,691 European ancestry controls, 6,828 unknown controls 6,107 European ancestry, Han Chinese ancestry and unknown ancestry 50% oldest-onset cases, 7,131 European ancestry, Han Chinese ancestry and unknown ancestry cases, 104,402 European ancestry controls, 5,537 Han Chinese ancestry controls, 14,291 unknown ancestry controls NR [1235109] (imputed) 1 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST003558 Genome-wide genotyping array 18489 2017-03-31 27531626 Polimanti R 2016-08-17 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/27531626 The Interplay Between Risky Sexual Behaviors and Alcohol Dependence: Genome-Wide Association and Neuroimaging Support for LHPP as a Risk Gene. Risky sexual behaviors (alcohol dependence interaction) 1,541 African American alcohol dependent cases, 1,436 European American alcohol dependent cases, 632 African American non-alcohol dependent controls, 315 European American non-alcohol dependent controls NA Illumina [at least 988306] (imputed) 1 behavioural disinhibition measurement, alcohol dependence, risky sexual behaviour measurement http://www.ebi.ac.uk/efo/EFO_0006946, http://www.ebi.ac.uk/efo/EFO_0003829, http://www.ebi.ac.uk/efo/EFO_0007877 GCST003860 Genome-wide genotyping array 3924 2019-03-18 30617256 Jansen IE 2019-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30617256 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk. Alzheimer's disease (late onset) 24,087 European ancestry cases, 55,058 European ancestry controls NA Illumina [up to 9862738] (imputed) 33 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST007319 Genome-wide genotyping array, Exome-wide sequencing 79145 2019-03-18 30617256 Jansen IE 2019-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30617256 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk. Family history of Alzheimer's disease 47,793 European ancestry cases, 328,320 European ancestry controls NA Affymetrix [10847151] (imputed) 33 family history of Alzheimer’s disease http://www.ebi.ac.uk/efo/EFO_0009268 GCST007321 Genome-wide genotyping array 376113 2019-03-18 30617256 Jansen IE 2019-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30617256 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk. Alzheimer's disease or family history of Alzheimer's disease 24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls NA Affymetrix, Illumina [up to 10847151] (imputed) 108 Alzheimer's disease, family history of Alzheimer’s disease http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0009268 GCST007320 Genome-wide genotyping array, Exome-wide sequencing 455258 2019-02-12 26920376 Wang Y 2016-02-26 Mult Scler www.ncbi.nlm.nih.gov/pubmed/26920376 Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors. Multiple sclerosis and systolic blood pressure (pleiotropy) 230,204 individuals NA NR [2382073] 3 multiple sclerosis, systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0003885, http://www.ebi.ac.uk/efo/EFO_0006335 GCST007125 Genome-wide genotyping array 230204 2019-02-12 26920376 Wang Y 2016-02-26 Mult Scler www.ncbi.nlm.nih.gov/pubmed/26920376 Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors. Multiple sclerosis and body mass index (pleiotropy) 151,013 individuals NA NR [2400377] 1 multiple sclerosis, body mass index http://www.ebi.ac.uk/efo/EFO_0003885, http://www.ebi.ac.uk/efo/EFO_0004340 GCST007126 Genome-wide genotyping array 151013 2019-02-12 26920376 Wang Y 2016-02-26 Mult Scler www.ncbi.nlm.nih.gov/pubmed/26920376 Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors. Multiple sclerosis and waist-to-hip-ratio (pleiotropy) 104,315 individuals NA NR [2376820] 1 multiple sclerosis, waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0003885, http://www.ebi.ac.uk/efo/EFO_0004343 GCST007127 Genome-wide genotyping array 104315 2019-02-12 26920376 Wang Y 2016-02-26 Mult Scler www.ncbi.nlm.nih.gov/pubmed/26920376 Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors. Multiple sclerosis and type 2 diabetes (pleiotropy) 49,192 individuals NA NR [2426886] 2 multiple sclerosis, type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0003885, http://www.ebi.ac.uk/efo/EFO_0001360 GCST007120 Genome-wide genotyping array 49192 2019-02-12 26920376 Wang Y 2016-02-26 Mult Scler www.ncbi.nlm.nih.gov/pubmed/26920376 Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors. Multiple sclerosis and C-reactive protein levels (pleiotropy) 93,333 individuals NA NR [2418544] 3 multiple sclerosis, C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0003885, http://www.ebi.ac.uk/efo/EFO_0004458 GCST007121 Genome-wide genotyping array 93333 2019-02-12 26920376 Wang Y 2016-02-26 Mult Scler www.ncbi.nlm.nih.gov/pubmed/26920376 Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors. Multiple sclerosis and triglyceride levels (pleiotropy) 215,725 individuals NA NR [2487152] 6 multiple sclerosis, triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0003885, http://www.ebi.ac.uk/efo/EFO_0004530 GCST007122 Genome-wide genotyping array 215725 2019-02-12 26920376 Wang Y 2016-02-26 Mult Scler www.ncbi.nlm.nih.gov/pubmed/26920376 Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors. Multiple sclerosis and LDL levels (pleiotropy) 215,725 individuals NA NR [2491989] 4 multiple sclerosis, low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0003885, http://www.ebi.ac.uk/efo/EFO_0004611 GCST007123 Genome-wide genotyping array 215725 2019-02-12 26920376 Wang Y 2016-02-26 Mult Scler www.ncbi.nlm.nih.gov/pubmed/26920376 Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors. Multiple sclerosis and HDL levels (pleiotropy) 215,725 individuals NA NR [2492237] 7 multiple sclerosis, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0003885, http://www.ebi.ac.uk/efo/EFO_0004612 GCST007124 Genome-wide genotyping array 215725 2017-01-25 27171184 Kuo HC 2016-05-12 PLoS One www.ncbi.nlm.nih.gov/pubmed/27171184 Genome-Wide Association Study Identifies Novel Susceptibility Genes Associated with Coronary Artery Aneurysm Formation in Kawasaki Disease. Coronary artery aneurysm in Kawasaki disease 11 Taiwanese ancestry cases, 146 Taiwanese ancestry controls NA Affymetrix [559609] 20 coronary aneurysm http://www.ebi.ac.uk/efo/EFO_1000881 GCST003560 Genome-wide genotyping array 157 2017-05-12 28030426 Mahmoudpour SH 2017-03-27 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/28030426 Meta-analysis of genome-wide association studies on the intolerance of angiotensin-converting enzyme inhibitors. Angiotensin-converting enzyme inhibitor intolerance 972 European ancestry intolerant individuals, 4,189 European ancestry tolerant individuals NA Affymetrix, Illumina [NR] (imputed) 45 response to angiotensin-converting enzyme inhibitor http://www.ebi.ac.uk/efo/EFO_0005325 GCST004029 Genome-wide genotyping array 5161 2017-03-27 27506219 Wang W 2016-08-09 Reprod Sci www.ncbi.nlm.nih.gov/pubmed/27506219 Pooling-Based Genome-Wide Association Study Identifies Risk Loci in the Pathogenesis of Ovarian Endometrioma in Chinese Han Women. Endometriosis 50 Chinese Han ancestry cases, 50 Chinese Han ancestry uterine myoma or hydrosalpinx controls 1,466 Chinese Han ancestry cases, 1,410 Chinese Han ancestry uterine myoma or hydrosalpinx controls Affymetrix [906600] 4 endometriosis http://www.ebi.ac.uk/efo/EFO_0001065 GCST003819 Genome-wide genotyping array 100 2018-05-30 29545352 Li Y 2018-03-15 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/29545352 Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms. Serum metabolite concentrations in chronic kidney disease 1,143 European ancestry cases NA Illumina [up to 9281895] (imputed) 40 serum metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005653 GCST005648 Genome-wide genotyping array 1143 2018-05-30 29545352 Li Y 2018-03-15 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/29545352 Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms. Urinary metabolite ratios in chronic kidney disease 1,143 European ancestry cases NA Illumina [up to 9281895] (imputed) 14 urinary metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005116 GCST005649 Genome-wide genotyping array 1143 2018-05-30 29545352 Li Y 2018-03-15 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/29545352 Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms. Serum metabolite ratios in chronic kidney disease 1,143 European ancestry cases NA Illumina [up to 9281895] (imputed) 259 serum metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005653 GCST005650 Genome-wide genotyping array 1143 2018-05-30 29545352 Li Y 2018-03-15 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/29545352 Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms. Urinary metabolite levels in chronic kidney disease 1,143 European ancestry cases NA Illumina [up to 9281895] (imputed) 9 urinary metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005116 GCST005651 Genome-wide genotyping array 1143 2018-06-04 29545352 Li Y 2018-03-15 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/29545352 Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms. Fractional excretion of metabolites in chronic kidney disease 1,143 European ancestry cases NA Illumina [up to 9281895] (imputed) 4 urinary metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005116 GCST005666 Genome-wide genotyping array 1143 2017-05-24 28065765 Nagao Y 2017-01-05 Clin Gastroenterol Hepatol www.ncbi.nlm.nih.gov/pubmed/28065765 Genome-Wide Association Study Identifies Risk Variants for Lichen Planus in Patients With Hepatitis C Virus Infection. Lichen planus in hepatitis C 71 Japanese ancestry cases, 190 Japanese ancestry controls 38 Italian ancestry cases, 7 Italian ancestry controls Affymetrix [629553] 0 lichen planus http://www.ebi.ac.uk/efo/EFO_1000726 GCST004090 Genome-wide genotyping array 261 2017-04-21 28041642 Carmona FD 2016-12-29 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/28041642 A Genome-wide Association Study Identifies Risk Alleles in Plasminogen and P4HA2 Associated with Giant Cell Arteritis. Giant cell arteritis 2,134 European ancestry cases, 9,125 European ancestry controls NA Illumina [1844133] (imputed) 5 temporal arteritis http://www.ebi.ac.uk/efo/EFO_1001209 GCST003928 Genome-wide genotyping array 11259 2018-06-01 29535710 Wahl A 2018-02-26 Front Immunol www.ncbi.nlm.nih.gov/pubmed/29535710 Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns. IgG glycosylation patterns 1,823 European ancestry individuals 1,836 European ancestry individuals Affymetrix [up to 18185628] (imputed) 310 serum IgG glycosylation measurement http://www.ebi.ac.uk/efo/EFO_0005193 GCST005656 Genome-wide genotyping array 1823 2017-05-12 28045058 Kim SW 2017-01-03 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28045058 Identification of genetic susceptibility loci for intestinal Behçet's disease. Behcet's disease 99 Korean ancestry cases with intestinal involvement, 100 Korean ancestry cases without intestinal involvement, 597 Korean ancestry controls. 196 Korean ancestry cases with intestinal involvement, 138 Korean ancestry cases without intestinal involvement, 391 Korean ancestry controls. Affymetrix [5418765] (imputed) 0 Behcet's syndrome http://www.ebi.ac.uk/efo/EFO_0003780 GCST004019 Genome-wide genotyping array 796 2017-05-31 28077804 Ben-Avraham D 2017-01-10 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/28077804 The complex genetics of gait speed: genome-wide meta-analysis approach. Gait speed in old age 31,478 European ancestry older adults 2,588 European ancestry older adults Affymetrix, Illumina [~ 2500000] (imputed) 19 gait measurement http://www.ebi.ac.uk/efo/EFO_0007680 GCST004110 Genome-wide genotyping array 31478 2017-04-11 28078323 Raj T 2016-12-21 Neurol Genet www.ncbi.nlm.nih.gov/pubmed/28078323 Genetic architecture of age-related cognitive decline in African Americans. Cognitive decline (age-related) 3,964 African American ancestry individuals. NA Illumina [13900000] (imputed) 20 Mental deterioration http://purl.obolibrary.org/obo/HP_0001268 GCST003901 Genome-wide genotyping array 3964 2017-05-19 28067912 Lee JC 2017-01-09 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28067912 Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease. Poor prognosis in Crohn's disease 1,762 Northern European ancestry poor prognosis cases, 972 Northern European ancestry good prognosis controls. NA Affymetrix, Illumina [at least 7000000] (imputed) 4 disease prognosis measurement http://www.ebi.ac.uk/efo/EFO_0007936 GCST004053 Genome-wide genotyping array 2734 2017-05-16 28070124 Meyers JL 2017-01-10 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/28070124 An endophenotype approach to the genetics of alcohol dependence: a genome wide association study of fast beta EEG in families of African ancestry. Fast beta electroencephalogram 2,382 African American individuals NA Illumina [12972748] (imputed) 1 electroencephalogram measurement http://www.ebi.ac.uk/efo/EFO_0004357 GCST004048 Genome-wide genotyping array 2382 2017-05-12 28049566 Direk N 2016-12-08 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/28049566 An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype. Depressive symptom measurement or major depressive disorder 9,240 European ancestry cases, 9,519 European ancestry controls, 51,150 European ancestry individuals with depressive symptom measurement 6,879 European ancestry cases, 13,453 European ancestry controls, 5,303 Chinese ancestry cases, 5,337 Chinese ancestry controls, 8,157 European American individuals with depressive symptom measurement Affymetrix, Illumina, Perlegen [918921] (imputed) 2 unipolar depression, depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0007006 GCST004024 Genome-wide genotyping array 69909 2017-05-16 28061514 Nannini DR 2017-01-01 Invest Ophthalmol Vis Sci www.ncbi.nlm.nih.gov/pubmed/28061514 A Genome-Wide Association Study of Vertical Cup-Disc Ratio in a Latino Population. Optic nerve measurement (cup-to-disc ratio) 3,596 Latino individuals 941 Latino individuals Illumina [6844888] (imputed) 4 cup-to-disc ratio measurement http://www.ebi.ac.uk/efo/EFO_0006939 GCST004047 Genome-wide genotyping array 3596 2018-02-27 29367735 Nakagawa-Senda H 2018-01-24 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29367735 A genome-wide association study in the Japanese population identifies the 12q24 locus for habitual coffee consumption: The J-MICC Study. Coffee consumption 6,312 Japanese ancestry individuals 4,949 Japanese ancestry individuals Illumina [7094228] (imputed) 1 cups of coffee per day measurement http://www.ebi.ac.uk/efo/EFO_0006782 GCST005329 Genome-wide genotyping array 6312 2018-02-27 29367735 Nakagawa-Senda H 2018-01-24 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29367735 A genome-wide association study in the Japanese population identifies the 12q24 locus for habitual coffee consumption: The J-MICC Study. Coffee consumption 11,261 Japanese ancestry individuals NA Illumina [7094228] (imputed) 4 cups of coffee per day measurement http://www.ebi.ac.uk/efo/EFO_0006782 GCST005330 Genome-wide genotyping array 11261 2018-03-12 29324852 Primes G 2018-01-11 PLoS One www.ncbi.nlm.nih.gov/pubmed/29324852 Real-life helping behaviours in North America: A genome-wide association approach. Helping behaviour (self reported) 10,713 European ancestry, African American and unknown ancestry individuals NA Illumina [1224134] (imputed) 7 helping behavior measurement http://www.ebi.ac.uk/efo/EFO_0008538 GCST005355 Genome-wide genotyping array 10713 2018-02-27 29327327 Lin X 2018-01-11 Mol Genet Genomics www.ncbi.nlm.nih.gov/pubmed/29327327 Identifying potentially common genes between dyslipidemia and osteoporosis using novel analytical approaches. Femoral neck bone mineral density or plasma lipids (pleiotropy) 49,988 European and unknown ancestry individuals with femoral neck bone mineral density measurements, 188,577 European and unknown ancestry individuals with plasma lipid measurements NA NR [~ 2000000] (imputed) 0 lipid measurement, femoral neck bone mineral density http://www.ebi.ac.uk/efo/EFO_0004529, http://www.ebi.ac.uk/efo/EFO_0007785 GCST005317 Genome-wide genotyping array 238565 2018-03-12 29346644 Yan Q 2018-01-15 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/29346644 Genome-wide Analysis of Disease Progression in Age-related Macular Degeneration. Disease progression in age-related macular degeneration 1,105 progressed eyes and 3,912 non-progressed eyes from 2,721 European ancestry individuals NA Illumina [8974355] (imputed) 28 age-related macular degeneration, disease progression measurement http://www.ebi.ac.uk/efo/EFO_0001365, http://www.ebi.ac.uk/efo/EFO_0008336 GCST005359 Genome-wide genotyping array 7738 2018-03-12 29346644 Yan Q 2018-01-15 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/29346644 Genome-wide Analysis of Disease Progression in Age-related Macular Degeneration. Disease progression to geographic atrophy form in age-related macular degeneration 615 progressed eyes and 3,912 non-progressed eyes from up to 2,721 European ancestry individuals NA Illumina [8974355] (imputed) 2 atrophic macular degeneration, disease progression measurement http://www.ebi.ac.uk/efo/EFO_1001492, http://www.ebi.ac.uk/efo/EFO_0008336 GCST005360 Genome-wide genotyping array 7248 2018-03-12 29346644 Yan Q 2018-01-15 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/29346644 Genome-wide Analysis of Disease Progression in Age-related Macular Degeneration. Disease progression to choroidal neovascularization form in age-related macular degeneration 508 progressed eyes and 3,912 non-progressed eyes from up to 2,721 European ancestry individuals NA Illumina [8974355] (imputed) 4 disease progression measurement, wet macular degeneration http://www.ebi.ac.uk/efo/EFO_0008336, http://www.ebi.ac.uk/efo/EFO_0004683 GCST005358 Genome-wide genotyping array 7141 2019-12-02 29346644 Yan Q 2018-01-15 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/29346644 Genome-wide Analysis of Disease Progression in Age-related Macular Degeneration. Disease progression in age-related macular degeneration (adjusted for baseline) 1,105 progressed eyes and 3,912 non-progressed eyes from 2,721 European ancestry individuals NA Illumina [8974355] (imputed) 34 disease progression measurement http://www.ebi.ac.uk/efo/EFO_0008336 GCST009144 Genome-wide genotyping array 7738 2017-09-15 28654678 Mandage R 2017-06-27 PLoS One www.ncbi.nlm.nih.gov/pubmed/28654678 Genetic factors affecting EBV copy number in lymphoblastoid cell lines derived from the 1000 Genome Project samples. Epstein-Barr virus copy number in lymphoblastoid cell lines 389 East Asian ancestry individuals, 189 South Asian ancestry individuals, 492 European ancestry individuals, 467 Sub-Saharan African ancestry individuals, 59 African American individuals, 157 Hispanic/Latino individuals NA NR [at least 880000] 42 Epstein-Barr virus infection http://www.ebi.ac.uk/efo/EFO_0000769 GCST004735 Genome-wide genotyping array 1753 2017-09-14 28651948 Peng C 2017-06-23 Bone www.ncbi.nlm.nih.gov/pubmed/28651948 Genetic sharing with coronary artery disease identifies potential novel loci for bone mineral density. Lumbar spine bone mineral density or coronary artery disease (pleiotropy) 53,236 individuals with bone mineral density measurements, 22,233 coronary artery disease cases, 64,762 controls NA NR [128164] (imputed) 0 spine bone mineral density, coronary artery disease http://www.ebi.ac.uk/efo/EFO_0007701, http://www.ebi.ac.uk/efo/EFO_0001645 GCST004717 Genome-wide genotyping array 140231 2017-09-16 28703135 Ruamviboonsuk P 2017-07-13 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/28703135 Genome-wide association study of neovascular age-related macular degeneration in the Thai population. Neovascular age-related macular degeneration 377 Thai ancestry cases, 1,074 Thai ancestry controls 222 Thai ancestry cases, 623 Thai ancestry controls Illumina [958497] 4 age-related macular degeneration, wet macular degeneration http://www.ebi.ac.uk/efo/EFO_0001365, http://www.ebi.ac.uk/efo/EFO_0004683 GCST004737 Genome-wide genotyping array 1451 2017-09-11 28642124 Hensman Moss DJ 2017-06-20 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/28642124 Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study. Huntington's disease progression 1,989 European and unknown ancestry mutation carriers NA Illumina [9650000] (imputed) 20 Huntington disease, disease progression measurement http://www.orpha.net/ORDO/Orphanet_399, http://www.ebi.ac.uk/efo/EFO_0008336 GCST004691 Genome-wide genotyping array 1989 2017-08-08 27363682 Mitchell JS 2016-07-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/27363682 Genome-wide association study identifies multiple susceptibility loci for multiple myeloma. Multiple myeloma 7,319 European ancestry cases, 234,385 European ancestry controls 2,547 European ancestry cases, 4,803 European ancestry controls Illumina [at least 7182761] (imputed) 23 multiple myeloma http://www.ebi.ac.uk/efo/EFO_0001378 GCST004483 Genome-wide genotyping array 241704 2017-09-14 24166409 Gelernter J 2014-01-01 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/24166409 Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci. Alcohol dependence 4,629 African American individuals, 5,131 European ancestry individuals 801 African American individuals, 1,746 European ancestry individuals Illumina [up to 10421983] (imputed) 49 alcohol dependence measurement http://www.ebi.ac.uk/efo/EFO_0007835 GCST004711 Genome-wide genotyping array 9760 2017-09-14 24166409 Gelernter J 2014-01-01 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/24166409 Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci. Alcohol dependence 2,415 African American cases, 1,798 African American controls, 2,669 European ancestry cases, 2,002 European ancestry controls 324 African American cases, 327 African American controls, 2,269 European ancestry cases, 2,975 European ancestry controls Illumina [up to 10421983] (imputed) 19 alcohol dependence http://www.ebi.ac.uk/efo/EFO_0003829 GCST004712 Genome-wide genotyping array 8884 2017-10-05 28869801 Takahashi Y 2017-09-04 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/28869801 Japanese genome-wide association study identifies a significant colorectal cancer susceptibility locus at chromosome 10p14. Colorectal cancer 529 Japanese ancestry cases, 521 Japanese ancestry controls 1,269 Japanese ancestry cases, 2,104 Japanese ancestry controls Affymetrix [280972] 1 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST004839 Genome-wide genotyping array 1050 2017-10-05 28869801 Takahashi Y 2017-09-04 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/28869801 Japanese genome-wide association study identifies a significant colorectal cancer susceptibility locus at chromosome 10p14. Colorectal cancer 529 Japanese ancestry cases, 521 Japanese ancestry controls 1,181 Japanese ancestry cases, 1,617 Japanese ancestry controls Affymetrix [280972] 0 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST004840 Genome-wide genotyping array 1050 2017-09-29 28808816 Xu C 2017-08-14 Biogerontology www.ncbi.nlm.nih.gov/pubmed/28808816 A genome-wide association study of cognitive function in Chinese adult twins. Cognitive function 139 Chinese ancestry dizygotic twin pairs NA Illumina [1048575] 12 cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0008354 GCST004823 Genome-wide genotyping array 139 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Very large HDL particle concentration 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 2 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST005492 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Phospholipid levels in very large HDL 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 0 phospholipid measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004639, http://www.ebi.ac.uk/efo/EFO_0004612 GCST005493 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Total cholesterol levels in very large HDL 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 0 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST005494 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Cholesterol ester levels in very large HDL 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 0 esterified cholesterol measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0008589, http://www.ebi.ac.uk/efo/EFO_0004612 GCST005495 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Free cholesterol levels in very large HDL 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 2 free cholesterol measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0008591, http://www.ebi.ac.uk/efo/EFO_0004612 GCST005496 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Triglyceride levels in very large HDL 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 19 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST005498 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Large HDL particle concentration 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 15 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST005497 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Phospholipid levels in large HDL 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 19 phospholipid measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004639, http://www.ebi.ac.uk/efo/EFO_0004612 GCST005499 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Total cholesterol levels in large HDL 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 3 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST005500 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Cholesterol ester levels in very large HDL 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 3 esterified cholesterol measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0008589, http://www.ebi.ac.uk/efo/EFO_0004612 GCST005501 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Free cholesterol levels in large HDL 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 5 free cholesterol measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0008591, http://www.ebi.ac.uk/efo/EFO_0004612 GCST005502 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Medium HDL particle concentration 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 11 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST005503 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Phospholipid levels in medium HDL 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 17 phospholipid measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004639, http://www.ebi.ac.uk/efo/EFO_0004612 GCST005504 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Total cholesterol levels in medium HDL 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 5 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST005505 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Cholesterol ester levels in medium HDL 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 5 esterified cholesterol measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0008589, http://www.ebi.ac.uk/efo/EFO_0004612 GCST005506 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Free cholesterol levels in medium HDL 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 6 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST005507 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Small HDL particle concentration 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 2 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST005508 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Triglyceride levels in small HDL 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 3 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST005509 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Chylomicron and largest VLDL particle concentration 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 2 chylomicron measurement, very low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0008596, http://www.ebi.ac.uk/efo/EFO_0008317 GCST005510 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Phospholipid levels in chylomicrons and largest VLDL 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 3 chylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipid measurement http://www.ebi.ac.uk/efo/EFO_0008596, http://www.ebi.ac.uk/efo/EFO_0008317, http://www.ebi.ac.uk/efo/EFO_0004639 GCST005511 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Triglyceride levels in chylomicrons and largest VLDL 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 1 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST005512 Genome-wide genotyping array 8372 2018-04-12 29084231 Davis JP 2017-10-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/29084231 Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. Apolipoprotein A1 levels 8,372 Finnish ancestry males NA Illumina [15144991] (imputed) 12 apolipoprotein A 1 measurement http://www.ebi.ac.uk/efo/EFO_0004614 GCST005513 Genome-wide genotyping array 8372 2017-03-30 27694991 Adams HH 2016-10-03 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/27694991 Novel genetic loci underlying human intracranial volume identified through genome-wide association. Intracranial volume 26,577 European ancestry individuals 2,362 European ancestry individuals, 938 African American individuals, 955 Asian ancestry individuals, 1,605 Hispanic individuals Affymetrix, Illumina, Perlegen [NR] (imputed) 0 intracranial volume measurement http://www.ebi.ac.uk/efo/EFO_0004886 GCST003834 Genome-wide genotyping array 26577 2017-01-16 27151647 Chen G 2016-05-05 Addict Biol www.ncbi.nlm.nih.gov/pubmed/27151647 An association study revealed substantial effects of dominance, epistasis and substance dependence co-morbidity on alcohol dependence symptom count. Alcohol dependence symptom count 2,605 European ancestry individuals, 1,233 African American individuals NA Illumina [974863] 6 alcohol dependence measurement http://www.ebi.ac.uk/efo/EFO_0007835 GCST003538 Genome-wide genotyping array 3838 2017-04-01 27764105 Lemmela S 2016-10-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/27764105 Genome-Wide Meta-Analysis of Sciatica in Finnish Population. Sciatica 291 Finnish (founder/genetic isolate) cases, 3,671 Finnish (founder/genetic isolate) controls 776 Finnish (founder/genetic isolate) cases, 18,489 Finnish (founder/genetic isolate) controls Illumina [~ 7700000] (imputed) 0 Sciatica http://purl.obolibrary.org/obo/HP_0011868 GCST003869 Genome-wide genotyping array 3962 2018-04-27 26651848 Rivera NV 2016-05-01 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/26651848 High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences. Sarcoidosis (non-Lofgren's syndrome) 568 Swedish ancestry cases, 2,025 Swedish ancestry controls 763 European ancestry cases, 4,901 European ancestry controls, 781 African American ancestry cases, 876 African American ancestry controls Illumina [118177] 1 Sarcoidosis http://www.orpha.net/ORDO/Orphanet_797 GCST005543 Targeted genotyping array [ImmunoChip] 2593 2018-04-27 26651848 Rivera NV 2016-05-01 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/26651848 High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences. Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) 451 Swedish ancestry cases, 2,086 Swedish ancestry controls NA Illumina [118177] 5 Sarcoidosis http://www.orpha.net/ORDO/Orphanet_797 GCST005542 Targeted genotyping array [ImmunoChip] 2537 2018-04-27 26651848 Rivera NV 2016-05-01 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/26651848 High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences. Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) 664 Swedish ancestry non-Lofgren's syndrome cases, 384 Swedish ancestry Lofgren's syndrome cases 413 German ancestry non-Lofgren's syndrome cases, 64 German ancestry Lofgren's syndrome cases Illumina [118177] 25 Sarcoidosis http://www.orpha.net/ORDO/Orphanet_797 GCST005541 Targeted genotyping array [ImmunoChip] 1048 2018-04-27 26651848 Rivera NV 2016-05-01 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/26651848 High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences. Sarcoidosis (Lofgren's syndrome) 345 Swedish ancestry cases, 2,025 Swedish ancestry controls 251 European ancestry cases, 4,901 European ancestry controls Illumina [118177] 1 Löfgren’s syndrome http://www.ebi.ac.uk/efo/EFO_0009466 GCST005540 Targeted genotyping array [ImmunoChip] 2370 2018-07-25 29296818 Clay-Gilmour AI 2017-09-08 Blood Adv www.ncbi.nlm.nih.gov/pubmed/29296818 Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex. B cell acute lymphoblastic leukaemia (normal cytogenetics) 193 European ancestry cases, 3027 European ancestry controls NA Illumina [~ 8500000] (imputed) 3 B-cell acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000094 GCST005965 Genome-wide genotyping array 3220 2018-07-25 29296818 Clay-Gilmour AI 2017-09-08 Blood Adv www.ncbi.nlm.nih.gov/pubmed/29296818 Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex. B cell acute lymphoblastic leukaemia (hyperdiploid negative) 410 European ancestry cases, 3027 European ancestry controls NA Illumina [~ 8500000] (imputed) 3 B-cell acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000094 GCST005966 Genome-wide genotyping array 3437 2018-07-25 29296818 Clay-Gilmour AI 2017-09-08 Blood Adv www.ncbi.nlm.nih.gov/pubmed/29296818 Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex. B cell acute lymphoblastic leukaemia (Philadelphia chromosome negative) 333 European ancestry cases, 3,027 European ancestry controls NA Illumina [~ 8500000] (imputed) 3 B-cell acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000094 GCST005967 Genome-wide genotyping array 3360 2018-07-25 29296818 Clay-Gilmour AI 2017-09-08 Blood Adv www.ncbi.nlm.nih.gov/pubmed/29296818 Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex. B cell acute lymphoblastic leukaemia (abnormal cytogenetics) 253 European ancestry cases, 3,027 European ancestry controls NA Illumina [~ 8500000] (imputed) 1 B-cell acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000094 GCST005968 Genome-wide genotyping array 3280 2018-07-25 29296818 Clay-Gilmour AI 2017-09-08 Blood Adv www.ncbi.nlm.nih.gov/pubmed/29296818 Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex. Acute lymphoblastic leukemia in childhood (B cell precursor) 134 European ancestry cases, 3,027 European ancestry controls NA Illumina [~ 8500000] (imputed) 1 B-cell acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000094 GCST005969 Genome-wide genotyping array 3161 2018-07-25 29296818 Clay-Gilmour AI 2017-09-08 Blood Adv www.ncbi.nlm.nih.gov/pubmed/29296818 Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex. B cell acute lymphoblastic leukaemia in young adulthood 160 European ancestry cases, 3,027 European ancestry controls NA Illumina [~ 8500000] (imputed) 1 B-cell acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000094 GCST005970 Genome-wide genotyping array 3187 2018-07-25 29296818 Clay-Gilmour AI 2017-09-08 Blood Adv www.ncbi.nlm.nih.gov/pubmed/29296818 Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex. B cell acute lymphoblastic leukaemia in adulthood 152 European ancestry cases, 3,027 European ancestry controls NA Illumina [~ 8500000] (imputed) 1 B-cell acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000094 GCST005971 Genome-wide genotyping array 3179 2018-07-25 29296818 Clay-Gilmour AI 2017-09-08 Blood Adv www.ncbi.nlm.nih.gov/pubmed/29296818 Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex. Acute lymphoblastic leukemia (B-cell precursor) 272 European ancestry male cases, 174 European ancestry female cases, 2,098 European ancestry male controls, 929 European ancestry female controls NA Illumina [~ 8500000] (imputed) 3 B-cell acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000094 GCST005972 Genome-wide genotyping array 3473 2018-04-25 23459209 Faraco J 2013-01-01 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/23459209 ImmunoChip study implicates antigen presentation to T cells in narcolepsy. Narcolepsy 1,886 European ancestry cases, 10,421 European ancestry controls NA Illumina [111240] 8 narcolepsy with cataplexy http://www.ebi.ac.uk/efo/EFO_0000614 GCST005522 Targeted genotyping array [ImmunoChip] 12307 2017-09-28 28763065 Xia K 2017-08-01 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/28763065 Genome-wide association analysis identifies common variants influencing infant brain volumes. Brain volume in infants (white matter) 295 European, African American, Asian, Native American and other admixed ancestry infants, 17 European, African American, Asian, Native American and other admixed ancestry sibling pairs, 116 European, African American, Asian, Native American and other admixed ancestry twin pairs. NA Affymetrix [8762422] (imputed) 6 infant white matter volume measurement http://www.ebi.ac.uk/efo/EFO_0008370 GCST004795 Genome-wide genotyping array 428 2017-09-28 28763065 Xia K 2017-08-01 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/28763065 Genome-wide association analysis identifies common variants influencing infant brain volumes. Brain volume in infants (cerebrospinal fluid) 295 European, African American, Asian, Native American and other admixed ancestry infants, 17 European, African American, Asian, Native American and other admixed ancestry sibling pairs, 116 European, African American, Asian, Native American and other admixed ancestry twin pairs. NA Affymetrix [8762422] (imputed) 4 infant cerebrospinal fluid volume measurement http://www.ebi.ac.uk/efo/EFO_0008367 GCST004796 Genome-wide genotyping array 428 2017-09-28 28763065 Xia K 2017-08-01 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/28763065 Genome-wide association analysis identifies common variants influencing infant brain volumes. Brain volume in infants (grey matter) 295 European, African American, Asian, Native American and other admixed ancestry infants, 17 European, African American, Asian, Native American and other admixed ancestry sibling pairs, 116 European, African American, Asian, Native American and other admixed ancestry twin pairs. NA Affymetrix [8762422] (imputed) 12 infant grey matter volume measurement http://www.ebi.ac.uk/efo/EFO_0008368 GCST004797 Genome-wide genotyping array 428 2017-09-28 28763065 Xia K 2017-08-01 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/28763065 Genome-wide association analysis identifies common variants influencing infant brain volumes. Brain volume in infants (intracranial brain volume) 295 European, African American, Asian, Native American and other admixed ancestry infants, 17 European, African American, Asian, Native American and other admixed ancestry sibling pairs, 116 European, African American, Asian, Native American and other admixed ancestry twin pairs. NA Affymetrix [8762422] (imputed) 3 infant intracranial volume measurement http://www.ebi.ac.uk/efo/EFO_0008369 GCST004794 Genome-wide genotyping array 428 2018-07-13 29212154 Lin E 2017-09-16 Oncotarget www.ncbi.nlm.nih.gov/pubmed/29212154 Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population. Metabolic syndrome 1,811 Taiwanese Han Chinese ancestry cases, 8,489 Taiwanese Han Chinese ancestry controls NA Affymetrix [583469] 2 metabolic syndrome http://www.ebi.ac.uk/efo/EFO_0000195 GCST005871 Genome-wide genotyping array 10300 2018-07-13 29212154 Lin E 2017-09-16 Oncotarget www.ncbi.nlm.nih.gov/pubmed/29212154 Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population. Waist circumference 1,811 Taiwanese Han Chinese individuals with metabolic syndrome, 8,489 Taiwanese Han Chinese ancestry individuals without metabolic syndrome NA Affymetrix [583469] 1 waist circumference http://www.ebi.ac.uk/efo/EFO_0004342 GCST005872 Genome-wide genotyping array 10300 2018-07-13 29212154 Lin E 2017-09-16 Oncotarget www.ncbi.nlm.nih.gov/pubmed/29212154 Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population. Triglyceride levels 1,811 Taiwanese Han Chinese individuals with metabolic syndrome, 8,489 Taiwanese Han Chinese ancestry individuals without metabolic syndrome NA Affymetrix [583469] 1 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST005873 Genome-wide genotyping array 10300 2018-07-13 29212154 Lin E 2017-09-16 Oncotarget www.ncbi.nlm.nih.gov/pubmed/29212154 Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population. HDL cholesterol 1,811 Taiwanese Han Chinese individuals with metabolic syndrome, 8,489 Taiwanese Han Chinese ancestry individuals without metabolic syndrome NA Affymetrix [583469] 1 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST005874 Genome-wide genotyping array 10300 2018-07-13 29212154 Lin E 2017-09-16 Oncotarget www.ncbi.nlm.nih.gov/pubmed/29212154 Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population. Diastolic blood pressure 1,811 Taiwanese Han Chinese individuals with metabolic syndrome, 8,489 Taiwanese Han Chinese ancestry individuals without metabolic syndrome NA Affymetrix [583469] 1 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST005875 Genome-wide genotyping array 10300 2018-07-13 29212154 Lin E 2017-09-16 Oncotarget www.ncbi.nlm.nih.gov/pubmed/29212154 Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population. Systolic blood pressure 1,811 Taiwanese Han Chinese individuals with metabolic syndrome, 8,489 Taiwanese Han Chinese ancestry individuals without metabolic syndrome NA Affymetrix [583469] 1 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST005876 Genome-wide genotyping array 10300 2018-07-13 29212154 Lin E 2017-09-16 Oncotarget www.ncbi.nlm.nih.gov/pubmed/29212154 Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population. Fasting blood glucose 1,811 Taiwanese Han Chinese individuals with metabolic syndrome, 8,489 Taiwanese Han Chinese ancestry individuals without metabolic syndrome NA Affymetrix [583469] 1 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST005877 Genome-wide genotyping array 10300 2018-01-12 28800628 Salem JE 2017-08-11 PLoS One www.ncbi.nlm.nih.gov/pubmed/28800628 "GENomE wide analysis of sotalol-induced IKr inhibition during ventricular REPOLarization, ""GENEREPOL study"": Lack of common variants with large effect sizes." Sotalol-induced IKr potassium channel inhibition (T wave peak and end interval change) 448 European ancestry individuals, 47 North African ancestry individuals 431 European ancestry individuals, 64 North African ancestry individuals Illumina [8306856] (imputed) 0 response to sotalol, TpTe measurement http://www.ebi.ac.uk/efo/EFO_0008325, http://www.ebi.ac.uk/efo/EFO_0008334 GCST005134 Genome-wide genotyping array 495 2018-01-12 28800628 Salem JE 2017-08-11 PLoS One www.ncbi.nlm.nih.gov/pubmed/28800628 "GENomE wide analysis of sotalol-induced IKr inhibition during ventricular REPOLarization, ""GENEREPOL study"": Lack of common variants with large effect sizes." Sotalol-induced IKr potassium channel inhibition (T wave maximal amplitude change) 448 European ancestry individuals, 47 North African ancestry individuals 431 European ancestry individuals, 64 North African ancestry individuals Illumina [8306856] (imputed) 0 response to sotalol, T wave amplitude http://www.ebi.ac.uk/efo/EFO_0008325, http://www.ebi.ac.uk/efo/EFO_0008333 GCST005135 Genome-wide genotyping array 495 2018-01-12 28800628 Salem JE 2017-08-11 PLoS One www.ncbi.nlm.nih.gov/pubmed/28800628 "GENomE wide analysis of sotalol-induced IKr inhibition during ventricular REPOLarization, ""GENEREPOL study"": Lack of common variants with large effect sizes." Sotalol-induced IKr potassium channel inhibition (ventricular repolarization duration change) 448 European ancestry individuals, 47 North African ancestry individuals 431 European ancestry individuals, 64 North African ancestry individuals Illumina [8306856] (imputed) 0 response to sotalol, ventricular repolarisation duration measurement http://www.ebi.ac.uk/efo/EFO_0008325, http://www.ebi.ac.uk/efo/EFO_0008335 GCST005140 Genome-wide genotyping array 495 2018-01-12 28800628 Salem JE 2017-08-11 PLoS One www.ncbi.nlm.nih.gov/pubmed/28800628 "GENomE wide analysis of sotalol-induced IKr inhibition during ventricular REPOLarization, ""GENEREPOL study"": Lack of common variants with large effect sizes." Sotalol-induced IKr potassium channel inhibition (ventricular repolarization changes PC2) 448 European ancestry individuals, 47 North African ancestry individuals 431 European ancestry individuals, 64 North African ancestry individuals Illumina [8306856] (imputed) 0 response to sotalol, T wave amplitude, TpTe measurement, ventricular repolarisation duration measurement http://www.ebi.ac.uk/efo/EFO_0008325, http://www.ebi.ac.uk/efo/EFO_0008333, http://www.ebi.ac.uk/efo/EFO_0008334, http://www.ebi.ac.uk/efo/EFO_0008335 GCST005136 Genome-wide genotyping array 495 2018-01-12 28800628 Salem JE 2017-08-11 PLoS One www.ncbi.nlm.nih.gov/pubmed/28800628 "GENomE wide analysis of sotalol-induced IKr inhibition during ventricular REPOLarization, ""GENEREPOL study"": Lack of common variants with large effect sizes." Sotalol-induced IKr potassium channel inhibition (ventricular repolarization changes PC3) 448 European ancestry individuals, 47 North African ancestry individuals 431 European ancestry individuals, 64 North African ancestry individuals Illumina [8306856] (imputed) 0 response to sotalol, T wave amplitude, TpTe measurement, ventricular repolarisation duration measurement http://www.ebi.ac.uk/efo/EFO_0008325, http://www.ebi.ac.uk/efo/EFO_0008333, http://www.ebi.ac.uk/efo/EFO_0008334, http://www.ebi.ac.uk/efo/EFO_0008335 GCST005138 Genome-wide genotyping array 495 2018-01-12 28800628 Salem JE 2017-08-11 PLoS One www.ncbi.nlm.nih.gov/pubmed/28800628 "GENomE wide analysis of sotalol-induced IKr inhibition during ventricular REPOLarization, ""GENEREPOL study"": Lack of common variants with large effect sizes." Sotalol-induced IKr potassium channel inhibition (ventricular repolarization changes PC1) 448 European ancestry individuals, 47 North African ancestry individuals 431 European ancestry individuals, 64 North African ancestry individuals Illumina [8306856] (imputed) 0 response to sotalol, T wave amplitude, TpTe measurement, ventricular repolarisation duration measurement http://www.ebi.ac.uk/efo/EFO_0008325, http://www.ebi.ac.uk/efo/EFO_0008333, http://www.ebi.ac.uk/efo/EFO_0008334, http://www.ebi.ac.uk/efo/EFO_0008335 GCST005139 Genome-wide genotyping array 495 2018-01-12 28800628 Salem JE 2017-08-11 PLoS One www.ncbi.nlm.nih.gov/pubmed/28800628 "GENomE wide analysis of sotalol-induced IKr inhibition during ventricular REPOLarization, ""GENEREPOL study"": Lack of common variants with large effect sizes." Sotalol-induced IKr potassium channel inhibition (T wave morphology notching) 448 European ancestry individuals, 47 North African ancestry individuals 431 European ancestry individuals, 64 North African ancestry individuals Illumina [8306856] (imputed) 0 response to sotalol, T wave morphology measurement http://www.ebi.ac.uk/efo/EFO_0008325, http://www.ebi.ac.uk/efo/EFO_0008398 GCST005137 Genome-wide genotyping array 495 2018-04-30 28714976 Sims R 2017-09-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28714976 Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Alzheimer's disease (late onset) up to 16,097 European ancestry cases, up to 18,077 European ancestry controls up to 20,693 European ancestry cases, up to 30,266 European ancestry controls Illumina [241551] 17 late-onset Alzheimers disease http://www.ebi.ac.uk/efo/EFO_1001870 GCST005549 Exome genotyping array 34174 2017-03-14 27623284 Verma SS 2016-09-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/27623284 Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium. Glaucoma (primary open-angle) 14 Black cases, 922 European ancestry cases, 25 cases, 82 Black controls, 3,918 European ancestry controls, 129 controls NA NR [2914185] 2 open-angle glaucoma http://www.ebi.ac.uk/efo/EFO_0004190 GCST003745 Genome-wide genotyping array 5090 2017-03-28 27612410 van der Plaat DA 2016-09-06 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/27612410 Genome-wide association study on the FEV1/FVC ratio in never-smokers identifies HHIP and FAM13A. Pre bronchodilator FEV1/FVC ratio in never-smokers 5,070 European ancestry individuals 1,966 European ancestry individuals Illumina [227981] 3 FEV/FEC ratio http://www.ebi.ac.uk/efo/EFO_0004713 GCST003826 Genome-wide genotyping array 5070 2016-12-21 27145994 Wang M 2016-05-05 Nat Commun www.ncbi.nlm.nih.gov/pubmed/27145994 Common genetic variation in ETV6 is associated with colorectal cancer susceptibility. Colorectal cancer 1,023 Han Chinese ancestry cases and 1,306 Han Chinese ancestry controls 5,317 Han Chinese ancestry cases, 6,887 Han Chinese ancestry controls, 1,046 European ancestry cases, 1,076 European ancestry controls Illumina [691326] 4 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST003494 Genome-wide genotyping array 2329 2017-02-24 27143689 Hertz DL 2016-05-03 Clin Cancer Res www.ncbi.nlm.nih.gov/pubmed/27143689 Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy. Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer 50 European ancestry cases with neuropathy, 573 European ancestry cases without neuropathy NA Illumina [498081] 12 peripheral neuropathy, response to docetaxel http://www.ebi.ac.uk/efo/EFO_0003100, http://purl.obolibrary.org/obo/GO_1902519 GCST003672 Genome-wide genotyping array 623 2016-12-16 27142678 Amin N 2016-05-04 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27142678 Genetic variants in RBFOX3 are associated with sleep latency. Sleep latency 1983 European ancestry individuals, 747 Erasmus Rucphen (founder/genetic isolate) individuals, 610 Korculan (founder/genetic isolate) individuals, 696 Tyrolean (founder/genetic isolate) individuals, 206 Orcadian (founder/genetic isolate) individuals 30,377 European ancestry individuals Affymetrix, Illumina, Perlegen [2572737] (imputed) 1 sleep latency http://www.ebi.ac.uk/efo/EFO_0005280 GCST003481 Genome-wide genotyping array 4242 2017-01-16 27149122 Smith JG 2016-05-05 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/27149122 Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure. Mortality in heart failure 1798 European ancestry cases, 1030 European ancestry controls 889 European ancestry cases, 981 European ancestry controls Affymetrix, Illumina [2500000] (imputed) 2 mortality http://www.ebi.ac.uk/efo/EFO_0004352 GCST003539 Genome-wide genotyping array 2828 2017-03-27 27639821 Scherag A 2016-09-15 EBioMedicine www.ncbi.nlm.nih.gov/pubmed/27639821 Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28Day Mortality. Mortality in sepsis 149 European ancestry cases, 591 European ancestry controls up to 2,534 individuals Illumina [7993459] (imputed) 15 mortality http://www.ebi.ac.uk/efo/EFO_0004352 GCST003817 Genome-wide genotyping array 740 2017-03-24 27694927 Vijayakrishnan J 2016-10-03 Leukemia www.ncbi.nlm.nih.gov/pubmed/27694927 A genome-wide association study identifies risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.1. Acute lymphoblastic leukemia in childhood (B cell precursor) 1,658 European ancestry child cases, 7,224 European ancestry controls 1,109 child cases, 1,412 European ancestry child cases, 2,085 controls, 1,479 European ancestry controls Illumina [11700000] (imputed) 2 B-cell acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000094 GCST003798 Genome-wide genotyping array 8882 2016-12-16 27142222 White MJ 2016-05-03 Immunogenetics www.ncbi.nlm.nih.gov/pubmed/27142222 Novel genetic risk factors for asthma in African American children: Precision Medicine and the SAGE II Study. Asthma (childhood onset) 812 African American child cases, 415 African American child controls NA Affymetrix [797128] 3 childhood onset asthma http://www.ebi.ac.uk/efo/EFO_0004591 GCST003482 Genome-wide genotyping array 1227 2016-12-14 27064256 Khor CC 2016-04-04 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27064256 Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma. Glaucoma (primary angle closure) 5,612 East Asian ancestry cases, 12,451 East Asian ancestry controls, 337 Indian ancestry cases, 2,538 Indian ancestry controls, 576 European ancestry cases, 4,940 European ancestry controls 430 European ancestry cases, 3,133 European ancestry controls, 90 Nepalese ancestry cases, 205 Nepalese ancestry controls, 2,340 East Asian ancestry cases, 3,865 East Asian ancestry controls, 628 South Asian ancestry cases, 552 South Asian ancestry controls, 99 Latin American cases, 224 Latin American controls, 391 Saudi Arabian ancestry cases, 1,659 Saudi Arabian ancestry controls Illumina [5245080] (imputed) 17 primary angle closure glaucoma http://www.ebi.ac.uk/efo/EFO_1001506 GCST003467 Genome-wide genotyping array 26454 2018-01-17 29210060 Koster R 2017-12-06 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/29210060 Genome-wide association study identifies the GLDC/IL33 locus associated with survival of osteosarcoma patients. Overall survival in osteosarcoma 523 European ancestry individuals 109 Brazilian ancestry individuals Illumina [510856] 9 osteosarcoma, overall survival http://www.ebi.ac.uk/efo/EFO_0000637, http://www.ebi.ac.uk/efo/EFO_0000638 GCST005158 Genome-wide genotyping array 523 2018-12-17 28957414 Pilling LC 2017-09-28 PLoS One www.ncbi.nlm.nih.gov/pubmed/28957414 Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers. Red cell distribution width 116,666 British ancestry individuals NA Affymetrix [16832071] (imputed) 195 red blood cell distribution width http://www.ebi.ac.uk/efo/EFO_0005192 GCST006804 Genome-wide genotyping array 116666 2018-12-19 29998114 Gadad BS 2018-05-03 Mol Neuropsychiatry www.ncbi.nlm.nih.gov/pubmed/29998114 Association of Novel ALX4 Gene Polymorphisms with Antidepressant Treatment Response: Findings from the CO-MED Trial. Remission after antidepressant treatment in major depression 119 European ancestry remitters and non-remitters NA Illumina [232877] 0 response to antidepressant http://purl.obolibrary.org/obo/GO_0036276 GCST006818 Genome-wide genotyping array 119 2018-12-19 29998114 Gadad BS 2018-05-03 Mol Neuropsychiatry www.ncbi.nlm.nih.gov/pubmed/29998114 Association of Novel ALX4 Gene Polymorphisms with Antidepressant Treatment Response: Findings from the CO-MED Trial. Response to antidepressants in depression 112 European ancestry responders, 98 European ancestry non-responders NA Illumina [232877] 5 response to antidepressant http://purl.obolibrary.org/obo/GO_0036276 GCST006817 Genome-wide genotyping array 210 2019-02-11 30674883 Jin Y 2019-01-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30674883 Early-onset autoimmune vitiligo associated with an enhancer variant haplotype that upregulates class II HLA expression. Vitiligo (late onset) 1,467 European ancestry cases, 19,156 European ancestry controls 977 European ancestry cases, 727 European ancestry controls NR [up to 494043] (imputed) 1 Vitiligo http://www.ebi.ac.uk/efo/EFO_0004208 GCST007112 Genome-wide genotyping array 20623 2019-02-11 30674883 Jin Y 2019-01-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30674883 Early-onset autoimmune vitiligo associated with an enhancer variant haplotype that upregulates class II HLA expression. Vitiligo (early onset) 704 European ancestry cases, 9,031 European ancestry controls 375 European ancestry cases, 1,455 European ancestry controls NR [up to 494043] (imputed) 2 Vitiligo http://www.ebi.ac.uk/efo/EFO_0004208 GCST007111 Genome-wide genotyping array 9735 2019-03-25 30745170 Strawbridge RJ 2019-02-07 EBioMedicine www.ncbi.nlm.nih.gov/pubmed/30745170 Identification of novel genome-wide associations for suicidality in UK Biobank, genetic correlation with psychiatric disorders and polygenic association with completed suicide. Deliberate self-harm 100,234 British ancestry individuals NA Affymetrix [9481578] (imputed) 1 suicide behaviour measurement http://www.ebi.ac.uk/efo/EFO_0006882 GCST007391 Genome-wide genotyping array 100234 2019-03-25 30745170 Strawbridge RJ 2019-02-07 EBioMedicine www.ncbi.nlm.nih.gov/pubmed/30745170 Identification of novel genome-wide associations for suicidality in UK Biobank, genetic correlation with psychiatric disorders and polygenic association with completed suicide. Suicidality (suicidal ideation/attempts) 108,090 British ancestry individuals NA Affymetrix [9481578] (imputed) 1 suicide behaviour measurement http://www.ebi.ac.uk/efo/EFO_0006882 GCST007390 Genome-wide genotyping array 108090 2019-03-25 30745170 Strawbridge RJ 2019-02-07 EBioMedicine www.ncbi.nlm.nih.gov/pubmed/30745170 Identification of novel genome-wide associations for suicidality in UK Biobank, genetic correlation with psychiatric disorders and polygenic association with completed suicide. Suicidality 122,808 British ancestry individuals NA Affymetrix [9481578] (imputed) 3 suicide behaviour measurement http://www.ebi.ac.uk/efo/EFO_0006882 GCST007389 Genome-wide genotyping array 122808 2019-02-21 30596066 Kong LL 2018-11-01 Ann Transl Med www.ncbi.nlm.nih.gov/pubmed/30596066 Genome-wide association study identifies RBFOX1 locus influencing brain glucose metabolism. Brain glucose metabolism (fluorodeoxyglucose uptake) 37 European ancestry Alzheimer's disease cases, 126 European ancestry individuals with mild cognitive impairment, 59 European ancestry controls NA Illumina [319792] 4 glucose metabolism measurement http://www.ebi.ac.uk/efo/EFO_0009367 GCST007206 Genome-wide genotyping array 222 2018-07-11 29531354 Malik R 2018-03-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29531354 Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Stroke 40,585 European ancestry cases, 406,111 European ancestry controls, 17,369 East Asian ancestry cases, 28,195 East Asian ancestry controls, 2,437 South Asian ancestry cases, 6,707 South Asian ancestry controls, 5,541 African American cases, 15,154 African American controls, 365 Asian ancestry cases, 333 Asian ancestry controls, 865 Latin American cases, 692 Latin American controls NA NR [~ 8000000] (imputed) 32 stroke http://www.ebi.ac.uk/efo/EFO_0000712 GCST005838 Genome-wide genotyping array 524354 2019-01-18 29531354 Malik R 2018-03-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29531354 Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Stroke 40,585 European ancestry cases, 406,111 European ancestry controls NA NR [~ 8000000] (imputed) 22 stroke http://www.ebi.ac.uk/efo/EFO_0000712 GCST006906 Genome-wide genotyping array 446696 2019-01-18 29531354 Malik R 2018-03-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29531354 Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Ischemic stroke (large artery atherosclerosis) 4,373 European ancestry cases, 406,111 European ancestry controls NA NR [~ 8000000] (imputed) 6 large artery stroke http://www.ebi.ac.uk/efo/EFO_0005524 GCST006907 Genome-wide genotyping array 410484 2019-01-18 29531354 Malik R 2018-03-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29531354 Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Ischemic stroke 34,217 European ancestry cases, 406,111 European ancestry controls NA NR [~ 8000000] (imputed) 19 Ischemic stroke http://purl.obolibrary.org/obo/HP_0002140 GCST006908 Genome-wide genotyping array 440328 2018-07-11 29531354 Malik R 2018-03-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29531354 Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Ischemic stroke (large artery atherosclerosis) 4,373 European ancestry cases, 406,111 European ancestry controls, 1,626 East Asian ancestry cases, 28,195 East Asian ancestry controls, 355 South Asian ancestry cases, 6,707 South Asian ancestry controls, 259 African American cases, 15,146 African American controls, 34 Asian ancestry cases, 333 Asian ancestry controls, 41 Latin American cases, 692 Latin American controls NA NR [~ 8000000] (imputed) 8 large artery stroke http://www.ebi.ac.uk/efo/EFO_0005524 GCST005840 Genome-wide genotyping array 463872 2018-07-11 29531354 Malik R 2018-03-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29531354 Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Ischemic stroke (small-vessel) 5,386 European ancestry cases, 192,662 European ancestry controls, 5,096 East Asian ancestry cases, 28,195 East Asian ancestry controls, 314 South Asian ancestry cases, 6,707 South Asian ancestry controls, 694 African American cases, 15,146 African American controls, 134 Asian ancestry cases, 333 Asian ancestry controls, 86 Latin American cases, 692 Latin American controls NA NR [~ 8000000] (imputed) 9 small vessel stroke http://www.ebi.ac.uk/efo/EFO_1001504 GCST005841 Genome-wide genotyping array 255445 2018-07-11 29531354 Malik R 2018-03-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29531354 Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Ischemic stroke (cardioembolic) 7,193 European ancestry cases, 406,111 European ancestry controls, 847 East Asian ancestry cases, 28,195 East Asian ancestry controls, 422 South Asian ancestry cases, 6,707 South Asian ancestry controls, 414 African American cases, 15,146 African American controls, 31 Asian ancestry cases, 333 Asian ancestry controls, 99 Latin American cases, 692 Latin American controls NA NR [~ 8000000] (imputed) 10 cardioembolic stroke http://www.ebi.ac.uk/efo/EFO_1001976 GCST005842 Genome-wide genotyping array 466190 2018-07-11 29531354 Malik R 2018-03-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29531354 Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Ischemic stroke 34,217 European ancestry cases, 406,111 European ancestry controls, 17,369 East Asian ancestry cases, 28,195 East Asian ancestry controls, 2,437 South Asian ancestry cases, 6,707 South Asian ancestry controls, 5,541 African American cases, 15,146 African American controls, 222 Asian ancestry cases, 333 Asian ancestry controls, 555 Latin American cases, 692 Latin American controls NA NR [~ 8000000] (imputed) 28 Ischemic stroke http://purl.obolibrary.org/obo/HP_0002140 GCST005843 Genome-wide genotyping array 517525 2019-01-18 29531354 Malik R 2018-03-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29531354 Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Ischemic stroke (small-vessel) 5,386 European ancestry cases, 192,662 European ancestry controls NA NR [~ 8000000] (imputed) 2 small vessel stroke http://www.ebi.ac.uk/efo/EFO_1001504 GCST006909 Genome-wide genotyping array 198048 2019-01-18 29531354 Malik R 2018-03-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29531354 Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Ischemic stroke (cardioembolic) 7,193 European ancestry cases, 406,111 European ancestry controls NA NR [~ 8000000] (imputed) 5 cardioembolic stroke http://www.ebi.ac.uk/efo/EFO_1001976 GCST006910 Genome-wide genotyping array 413304 2019-03-19 30604766 Morris AP 2019-01-03 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30604766 Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies. Estimated glomerular filtration rate 134,070 European ancestry individuals, 143,658 East Asian ancestry individuals, 26,344 Hispanic or Latino ancestry individuals, 8,224 African American individuals NA Affymetrix, Illumina [at least 5248638] (imputed) 136 glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0005208 GCST007344 Genome-wide genotyping array 312296 2019-01-29 30610198 Soler Artigas M 2019-01-04 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30610198 Attention-deficit/hyperactivity disorder and lifetime cannabis use: genetic overlap and causality. Attention deficit hyperactivity disorder or cannabis use 18,345 European ancestry ADHD cases, 14,374 European ancestry cannabis use cases, 50,410 European ancestry controls NA NR [5009020] (imputed) 16 attention deficit hyperactivity disorder, Cannabis use http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0007585 GCST006983 Genome-wide genotyping array 83129 2019-07-11 31163085 Sharapov SZ 2019-06-15 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31163085 Defining the genetic control of human blood plasma N-glycome using genome-wide association study. N-glycan levels 2,763 individuals 327 Arab, South Asian and Filipino ancestry individuals, 294 European ancestry individuals, 591 individuals. Illumina [8557543] (imputed) 7 N-glycan measurement http://www.ebi.ac.uk/efo/EFO_0004999 GCST008108 Genome-wide genotyping array 2763 2019-05-07 30610941 Wang AW 2019-01-02 Prog Neuropsychopharmacol Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30610941 Genome-wide association study in two populations to determine genetic variants associated with Toxoplasma gondii infection and relationship to schizophrenia risk. Anti-Toxoplasma gondii IgG seropositivity 256 Ashkenazi Jewish cases, 68 African American cases, 534 Ashkenazi Jewish controls, 217 African American controls NA Affymetrix, Illumina [up to 1101633] (imputed) 4 Toxoplasma gondii seropositivity http://www.ebi.ac.uk/efo/EFO_0007047 GCST007726 Genome-wide genotyping array 1075 2019-08-05 31168069 Ward J 2019-06-05 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/31168069 The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function. Mood instability 157,039 European ancestry cases, 206,666 European ancestry controls NA Affymetrix [NR] (imputed) 46 mood instability measurement http://www.ebi.ac.uk/efo/EFO_0008475 GCST008357 Genome-wide genotyping array 363705 2015-04-01 25035420 Hong KW 2014-07-17 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/25035420 Identification of three novel genetic variations associated with electrocardiographic traits (QRS duration and PR interval) in East Asians. PR interval 6,085 Korean ancestry individuals 7,295 Japanese ancestry individuals Affymetrix [2100000] (imputed) 5 PR interval http://www.ebi.ac.uk/efo/EFO_0004462 GCST002535 Genome-wide genotyping array 6085 2015-04-01 25035420 Hong KW 2014-07-17 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/25035420 Identification of three novel genetic variations associated with electrocardiographic traits (QRS duration and PR interval) in East Asians. QRS duration 6,085 Korean ancestry individuals 7,295 Japanese ancestry individuals Affymetrix [2100000] (imputed) 6 QRS duration http://www.ebi.ac.uk/efo/EFO_0005055 GCST002533 Genome-wide genotyping array 6085 2015-07-24 25476525 Germain M 2014-12-06 Diabetologia www.ncbi.nlm.nih.gov/pubmed/25476525 SORBS1 gene, a new candidate for diabetic nephropathy: results from a multi-stage genome-wide association study in patients with type 1 diabetes. Diabetic nephropathy in type 1 diabetes 683 European ancestry cases, 779 European ancestry controls 2,962 European ancestry cases, 3,379 European ancestry controls Illumina [11133962] (imputed) 1 diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0000401 GCST002716 Genome-wide genotyping array 1462 2015-07-27 25429627 Oryoji D 2014-11-27 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/25429627 Identification of a Hashimoto thyroiditis susceptibility locus via a genome-wide comparison with Graves' disease. Hashimoto thyroiditis versus Graves' disease 263 Japanese ancestry Hashimoto thyroiditis cases, 260 Japanese ancestry Graves’ disease cases 181 Japanese ancestry Hashimoto thyroiditis cases, 286 Japanese ancestry Graves’ disease cases Illumina [546173] 3 autoimmune thyroid disease, Hashimoto's thyroiditis, Graves disease http://www.ebi.ac.uk/efo/EFO_0006812, http://www.ebi.ac.uk/efo/EFO_0003779, http://www.ebi.ac.uk/efo/EFO_0004237 GCST002705 Genome-wide genotyping array 523 2014-11-18 24847357 Ye Z 2014-05-09 Front Genet www.ncbi.nlm.nih.gov/pubmed/24847357 Genome wide association study of SNP-, gene-, and pathway-based approaches to identify genes influencing susceptibility to Staphylococcus aureus infections. Staphylococcus aureus infection 309 European ancestry cases, 2,925 European ancestry controls NA Illumina [508921] 4 Staphylococcus aureus infection http://www.ebi.ac.uk/efo/EFO_0005681 GCST002440 Genome-wide genotyping array 3234 2014-07-01 21102462 Elks CE 2010-11-21 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21102462 Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Menarche (age at onset) 86,142 European ancestry female individuals, 557 Old Order Amish (founder/genetic isolate) female individuals, 1,103 Erasmus Rucphen (founder/genetic isolate) female individuals Up to 12,813 European ancestry female individuals, 910 Val Borbera (founder/genetic isolate) female individuals, 348 Orcadian (founder/genetic isolate) female individuals, 338 Friuli Venezia Giulia (founder/genetic isolate) female individuals, 322 Carlantino (founder/genetic/isolate) female individuals Affymetrix, Illumina [~ 2500000] (imputed) 42 age at menarche http://www.ebi.ac.uk/efo/EFO_0004703 GCST000880 Genome-wide genotyping array 87802 2015-10-24 25561047 Musani SK 2015-01-05 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/25561047 Genome-wide association analysis of plasma B-type natriuretic peptide in blacks: the Jackson Heart Study. B-type natriuretic peptide levels 2,790 Black individuals NA Affymetrix [2500000] (imputed) 2 BNP measurement http://www.ebi.ac.uk/efo/EFO_0006920 GCST002736 Genome-wide genotyping array 2790 2015-10-26 25574032 Lee H 2015-01-08 Hum Reprod www.ncbi.nlm.nih.gov/pubmed/25574032 Genome-wide association study identified new susceptibility loci for polycystic ovary syndrome. Polycystic ovary syndrome 976 Korean ancestry cases, 946 Korean ancestry controls 249 Korean ancestry cases, 778 Korean ancestry controls Illumina [636870] 3 polycystic ovary syndrome http://www.ebi.ac.uk/efo/EFO_0000660 GCST002741 Genome-wide genotyping array 1922 2014-10-06 24529757 Xie T 2014-01-17 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/24529757 Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations. Amyotrophic lateral sclerosis (sporadic) 250 Han Chinese ancestry cases, 250 Han Chinese ancestry controls NA Illumina [859311] 175 sporadic amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0001357 GCST002337 Genome-wide genotyping array 500 2014-05-03 24166486 Sleiman P 2013-10-29 Sci Rep www.ncbi.nlm.nih.gov/pubmed/24166486 GWAS meta analysis identifies TSNARE1 as a novel Schizophrenia / Bipolar susceptibility locus. Schizophrenia, schizoaffective disorder or bipolar disorder 11,985 European, African American, Asian, other and unknown ancestry schizophrenia cases, 377 European, African American, Asian, other and unknown ancestry schizoaffective disorder cases, 1,032 bipolar disorder cases, 34,676 European, African American, Asian, other and unknown ancestry controls 2652 individuals Affymetrix, Illumina [NR] (imputed) 5 schizophrenia, bipolar disorder, schizoaffective disorder http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0000289, http://www.ebi.ac.uk/efo/EFO_0005411 GCST002254 Genome-wide genotyping array 48070 2008-06-16 17804789 Raelson JV 2007-09-05 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/17804789 Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci. Crohn's disease 382 French Canadian founder trios 750 European ancestry cases, 828 European ancestry controls, 521 European ancestry trios Perlegen [164279] 3 Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000384 GCST000071 Genome-wide genotyping array 382 2014-05-12 24097068 Willer CJ 2013-10-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24097068 Discovery and refinement of loci associated with lipid levels. LDL cholesterol 94,595 European ancestry individuals up to 4,420 African ancestry individuals NR [NR] (imputed) 1 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST002220 Genome-wide genotyping array 94595 2014-05-13 24097068 Willer CJ 2013-10-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24097068 Discovery and refinement of loci associated with lipid levels. Triglycerides 94,595 European ancestry individuals 8,743 East Asian ancestry individuals NR [NR] (imputed) 1 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST002219 Genome-wide genotyping array 94595 2014-05-12 24097068 Willer CJ 2013-10-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24097068 Discovery and refinement of loci associated with lipid levels. HDL cholesterol 94,595 European ancestry individuals 93,982 European ancestry individuals NR [NR] (imputed) 71 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST002223 Genome-wide genotyping array 94595 2014-05-12 24097068 Willer CJ 2013-10-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24097068 Discovery and refinement of loci associated with lipid levels. LDL cholesterol 94,595 European ancestry individuals 93,982 European ancestry individuals NR [NR] (imputed) 58 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST002222 Genome-wide genotyping array 94595 2014-05-12 24097068 Willer CJ 2013-10-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24097068 Discovery and refinement of loci associated with lipid levels. Cholesterol, total 94,595 European ancestry individuals 93,982 European ancestry individuals NR [NR] (imputed) 73 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST002221 Genome-wide genotyping array 94595 2014-05-12 24097068 Willer CJ 2013-10-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24097068 Discovery and refinement of loci associated with lipid levels. Triglycerides 94,595 European ancestry individuals 93,982 European ancestry individuals NR [NR] (imputed) 40 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST002216 Genome-wide genotyping array 94595 2014-11-01 24625756 Yu B 2014-03-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/24625756 Genetic determinants influencing human serum metabolome among African Americans. Serum metabolite levels 1,260 African American individuals NA Affymetrix [2341704] (imputed) 19 serum metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005653 GCST002388 Genome-wide genotyping array 1260 2015-12-18 25574825 Baurecht H 2015-01-08 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/25574825 Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms. Inflammatory skin disease 2,079 European ancestry atopic dermatitis cases, 4,212 European ancestry psoriasis cases, 11,899 European ancestry controls NA Affymetrix, Illumina [~ 5200000] 88 inflammatory skin disease http://www.ebi.ac.uk/efo/EFO_1000636 GCST002740 Genome-wide genotyping array 18190 2016-01-12 25574825 Baurecht H 2015-01-08 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/25574825 Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms. Atopic dermatitis 2,079 European ancestry cases, 3,867 European ancestry controls NA Affymetrix, Illumina, Perlegen [up to 5493100] (imputed) 7 atopic eczema http://www.ebi.ac.uk/efo/EFO_0000274 GCST002737 Genome-wide genotyping array 5946 2016-01-06 25574825 Baurecht H 2015-01-08 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/25574825 Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms. Psoriasis 4,212 European ancestry cases, 8,032 European ancestry controls NA Affymetrix, Illumina, Perlegen [up to 5493100] (imputed) 20 psoriasis http://www.ebi.ac.uk/efo/EFO_0000676 GCST002738 Genome-wide genotyping array 12244 2015-09-24 25282103 Wood AR 2014-10-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/25282103 Defining the role of common variation in the genomic and biological architecture of adult human height. Height 253,288 European ancestry individuals 80,067 European ancestry individuals Affymetrix, Illumina, Perlegen [2550858] (imputed) 173 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST002647 Genome-wide genotyping array 253288 2015-09-22 25524916 Palmer ND 2014-12-18 Diabetes www.ncbi.nlm.nih.gov/pubmed/25524916 Genetic Variants Associated With Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium. Glucose homeostasis traits up to 4,176 Mexican American individuals NA Illumina [693128] 74 insulin metabolic clearance rate measurement, disposition index measurement, insulin sensitivity measurement, glucose homeostasis measurement, glucose effectiveness measurement, acute insulin response measurement http://www.ebi.ac.uk/efo/EFO_0006830, http://www.ebi.ac.uk/efo/EFO_0006832, http://www.ebi.ac.uk/efo/EFO_0004471, http://www.ebi.ac.uk/efo/EFO_0006896, http://www.ebi.ac.uk/efo/EFO_0006833, http://www.ebi.ac.uk/efo/EFO_0006831 GCST002726 Genome-wide genotyping array 4176 2015-05-23 25281661 Matsuda K 2014-10-03 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/25281661 Genome-wide association study identified SNP on 15q24 associated with bladder cancer risk in Japanese population. Bladder cancer 531 Japanese ancestry cases, 5,581 Japanese ancestry conrols 592 Japanese ancestry cases, 6,964 Japanese ancestry controls, 3,508 European ancestry cases, 5,101 European ancestry controls Illumina [554389] 1 bladder carcinoma http://www.ebi.ac.uk/efo/EFO_0000292 GCST002645 Genome-wide genotyping array 6112 2012-10-24 20881960 Lango Allen H 2010-09-29 Nature www.ncbi.nlm.nih.gov/pubmed/20881960 Hundreds of variants clustered in genomic loci and biological pathways affect human height. Height 133,653 European ancestry individuals 50,074 European ancestry individuals Affymetrix, Illumina [2834208] (imputed) 199 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST000817 Genome-wide genotyping array 133653 2011-10-21 21909115 Ehret GB 2011-09-11 Nature www.ncbi.nlm.nih.gov/pubmed/21909115 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Systolic blood pressure 69,395 European ancestry individuals Up to 133,361 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 20 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST001227 Genome-wide genotyping array 69395 2011-10-21 21909115 Ehret GB 2011-09-11 Nature www.ncbi.nlm.nih.gov/pubmed/21909115 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Hypertension 69,395 European ancestry individuals Up to 133,361 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 11 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST001238 Genome-wide genotyping array 69395 2011-10-21 21909115 Ehret GB 2011-09-11 Nature www.ncbi.nlm.nih.gov/pubmed/21909115 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Diastolic blood pressure 69,395 European ancestry individuals Up to 133,361 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 19 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST001228 Genome-wide genotyping array 69395 2011-09-28 21874001 Kooner JS 2011-08-28 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21874001 Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. Type 2 diabetes 5,561 South Asian ancestry cases, 14,458 South Asian ancestry controls 13,170 South Asian ancestry cases, 25,398 South Asian ancestry controls Illumina [568976] 6 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST001213 Genome-wide genotyping array 20019 2011-10-22 21956439 Zuo L 2011-09-28 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/21956439 Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. Alcohol dependence 1,409 European ancestry cases, 1,518 European ancestry controls, 681 African American cases, 508 African American controls NA Illumina [805814] 3 alcohol dependence http://www.ebi.ac.uk/efo/EFO_0003829 GCST001254 Genome-wide genotyping array 4116 2012-07-19 22664479 Han JY 2012-06-05 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/22664479 A genome-wide association study for irinotecan-related severe toxicities in patients with advanced non-small-cell lung cancer. Response to irinotecan in non-small-cell lung cancer 101 non-small-cell lung cancer cases 146 non-small-cell lung cancer cases Affymetrix [312230] 2 response to irinotecan http://www.ebi.ac.uk/efo/EFO_0004829 GCST001558 Genome-wide genotyping array 101 2013-05-10 23322567 Lopes MC 2013-01-15 Invest Ophthalmol Vis Sci www.ncbi.nlm.nih.gov/pubmed/23322567 Identification of a candidate gene for astigmatism. Corneal astigmatism 22,100 European ancestry individuals NA Affymetrix, Illumina [2800000] (imputed) 17 Astigmatism http://purl.obolibrary.org/obo/HP_0000483 GCST001819 Genome-wide genotyping array 22100 2012-03-15 22383894 Pierce BL 2012-02-23 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22383894 Genome-wide association study identifies chromosome 10q24.32 variants associated with arsenic metabolism and toxicity phenotypes in Bangladesh. Arsenic metabolism 1,313 Bangladeshi ancestry individuals NA Illumina [259597] 2 urinary arsenic measurement http://www.ebi.ac.uk/efo/EFO_0004880 GCST001421 Genome-wide genotyping array 1313 2011-09-28 21900944 Shen H 2011-09-08 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/21900944 Genome-wide association study identifies genetic variants in GOT1 determining serum aspartate aminotransferase levels. Aspartate aminotransferase levels 866 Old Order Amish individuals NA Affymetrix [373825] 1 aspartate aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004736 GCST001222 Genome-wide genotyping array 866 2011-06-29 21665990 Yu Y 2011-06-10 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21665990 Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration. Age-related macular degeneration 2,594 European ancestry cases, 4,134 European ancestry controls 5,640 European ancestry cases, 52,174 European ancestry controls Affymetrix [6036699] (imputed) 11 age-related macular degeneration http://www.ebi.ac.uk/efo/EFO_0001365 GCST001100 Genome-wide genotyping array 6728 2011-08-12 21784300 Mick E 2011-07-13 J Am Acad Child Adolesc Psychiatry www.ncbi.nlm.nih.gov/pubmed/21784300 Genome-wide association study of the child behavior checklist dysregulation profile. Attention deficit hyperactivity disorder 341 ADHD case offspring from 339 trios NA Illumina [835136] 7 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST001154 Genome-wide genotyping array 680 2010-11-17 20935630 Speliotes EK 2010-10-10 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20935630 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Body mass index Up to 123,865 European ancestry individuals Up to 125,931 European ancestry individuals Affymetrix, Illumina, Perlegen [~ 2800000] (imputed) 38 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST000830 Genome-wide genotyping array 123865 2011-08-15 21779381 Schurks M 2011-07-14 PLoS One www.ncbi.nlm.nih.gov/pubmed/21779381 Genetic determinants of cardiovascular events among women with migraine: a genome-wide association study. Cardiovascular disease risk factors 5,122 European ancestry female migrain cases NA Illumina [339596] 5 cardiovascular disease http://www.ebi.ac.uk/efo/EFO_0000319 GCST001157 Genome-wide genotyping array 5122 2015-05-05 22139419 Gieger C 2011-11-30 Nature www.ncbi.nlm.nih.gov/pubmed/22139419 New gene functions in megakaryopoiesis and platelet formation. Mean platelet volume 13,106 European ancestry individuals, 1,652 Val Borbera (founder/genetic isolate) individuals, 593 Carlantino (founder/genetic isolate) individuals, 1,146 Friuli Venezia Giulia (founder/genetic isolate) individuals, 1,213 South Tyrolean (founder/genetic isolate) individuals, 890 Sorbian (founder/genetic isolate) individuals Up to 16,960 European ancestry individuals, 855 Cliento (founder/genetic isolate) individuals, 1,023 Talana (founder/genetic isolate) individuals Affymetrix, Illumina [~ 2500000] (imputed) 29 mean platelet volume http://www.ebi.ac.uk/efo/EFO_0004584 GCST001335 Genome-wide genotyping array 18600 2015-05-05 22139419 Gieger C 2011-11-30 Nature www.ncbi.nlm.nih.gov/pubmed/22139419 New gene functions in megakaryopoiesis and platelet formation. Platelet count 38,891 European ancestry individuals, 1,661 Val Borbera (founder/genetic isolate) individuals, 521 Carlantino (founder/genetic isolate) individuals, 1,198 Friuli Venezia Giulia (founder/genetic isolate) individuals, 1,213 South Tyrolean (founder/genetic isolate) individuals, 890 Sorbian (founder/genetic isolate) individuals, 4,292 Sardinian (founder/genetic isolate) individuals Up to 16,949 European ancestry individuals, 854 Cliento (founder/genetic isolate) individuals, 1,035 Talana (founder/genetic isolate) individuals Affymetrix, Illumina [~ 2500000] (imputed) 56 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST001337 Genome-wide genotyping array 48666 2012-10-23 22911880 Boraska V 2012-08-22 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/22911880 Genome-wide association analysis of eating disorder-related symptoms, behaviors, and personality traits. Eating disorders Up to 2,567 European ancestry individuals Up to 767 European ancestry cases, up to 486 European ancestry controls Illumina [283744] 7 mental or behavioural disorder http://www.ebi.ac.uk/efo/EFO_0000677 GCST001644 Genome-wide genotyping array 2567 2013-09-16 23643386 Hatoum IJ 2013-05-02 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/23643386 Weight loss after gastric bypass is associated with a variant at 15q26.1. Weight loss (gastric bypass surgery) 693 European ancestry individuals 327 European ancestry individuals Illumina [1943170] (imputed) 5 body weight loss http://www.ebi.ac.uk/efo/EFO_0005245 GCST001991 Genome-wide genotyping array 693 2012-08-14 22832960 Service SK 2012-05-15 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/22832960 A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales. Temperament Up to 12,433 European ancestry individuals NA Affymetrix, Illumina [1252222] (imputed) 16 temperament and character inventory http://www.ebi.ac.uk/efo/EFO_0004825 GCST001531 Genome-wide genotyping array 12433 2013-02-12 23128233 Jostins L 2012-11-01 Nature www.ncbi.nlm.nih.gov/pubmed/23128233 Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Crohn's disease Up to 12,924 European ancestry cases, up to 21,442 European ancestry controls Up to 25,683 European ancestry cases, up to 17,015 European ancestry controls Affymetrix, Illumina [1230000] (imputed) 30 Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000384 GCST001729 Genome-wide genotyping array 34366 2013-02-12 23128233 Jostins L 2012-11-01 Nature www.ncbi.nlm.nih.gov/pubmed/23128233 Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Ulcerative colitis Up to 12,924 European ancestry cases, up to 21,442 European ancestry controls Up to 25,683 European ancestry cases, up to 17,015 European ancestry controls Affymetrix, Illumina [1230000] (imputed) 23 ulcerative colitis http://www.ebi.ac.uk/efo/EFO_0000729 GCST001728 Genome-wide genotyping array 34366 2013-02-12 23128233 Jostins L 2012-11-01 Nature www.ncbi.nlm.nih.gov/pubmed/23128233 Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Inflammatory bowel disease 12,924 European ancestry cases, 21,442 European ancestry controls 25,683 European ancestry cases, 17,015 European ancestry controls Affymetrix, Illumina [1230000] (imputed) 110 inflammatory bowel disease http://www.ebi.ac.uk/efo/EFO_0003767 GCST001725 Genome-wide genotyping array 34366 2014-03-26 24025145 Chung S 2013-09-11 Breast Cancer Res www.ncbi.nlm.nih.gov/pubmed/24025145 A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients. Adverse response to chemotherapy in breast cancer (alopecia) 303 Japanese ancestry cases, 880 Japanese ancestry controls 23 Japanese ancestry cases Illumina [555600] 3 chemotherapy-induced alopecia http://www.ebi.ac.uk/efo/EFO_0005400 GCST002181 Genome-wide genotyping array 1183 2014-03-26 24025145 Chung S 2013-09-11 Breast Cancer Res www.ncbi.nlm.nih.gov/pubmed/24025145 A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients. Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+epirubicin+/-5FU) 116 Japanese ancestry cases, 108 Japanese ancestry controls NA Illumina [555600] 3 response to epirubicin, response to cyclophosphamide, chemotherapy-induced alopecia, response to 5' fluorouracil http://purl.obolibrary.org/obo/GO_1902522, http://purl.obolibrary.org/obo/GO_1902518, http://www.ebi.ac.uk/efo/EFO_0005400, http://purl.obolibrary.org/obo/GO_0036275 GCST002176 Genome-wide genotyping array 224 2014-03-27 24025145 Chung S 2013-09-11 Breast Cancer Res www.ncbi.nlm.nih.gov/pubmed/24025145 A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients. Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) 64 Japanese ancestry cases, 27 Japanese ancestry controls NA Illumina [555600] 8 response to cyclophosphamide, chemotherapy-induced alopecia, response to 5' fluorouracil, response to doxorubicin http://purl.obolibrary.org/obo/GO_1902518, http://www.ebi.ac.uk/efo/EFO_0005400, http://purl.obolibrary.org/obo/GO_0036275, http://purl.obolibrary.org/obo/GO_1902520 GCST002178 Genome-wide genotyping array 91 2014-03-26 24025145 Chung S 2013-09-11 Breast Cancer Res www.ncbi.nlm.nih.gov/pubmed/24025145 A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients. Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel) 57 Japanese ancestry cases, 63 Japanese ancestry controls NA Illumina [555600] 5 chemotherapy-induced alopecia, response to paclitaxel http://www.ebi.ac.uk/efo/EFO_0005400, http://purl.obolibrary.org/obo/GO_1901555 GCST002179 Genome-wide genotyping array 120 2014-03-26 24025145 Chung S 2013-09-11 Breast Cancer Res www.ncbi.nlm.nih.gov/pubmed/24025145 A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients. Adverse response to chemotherapy in breast cancer (alopecia) (docetaxel) 62 Japanese ancestry cases, 42 Japanese ancestry controls NA Illumina [555600] 4 chemotherapy-induced alopecia, response to docetaxel http://www.ebi.ac.uk/efo/EFO_0005400, http://purl.obolibrary.org/obo/GO_1902519 GCST002180 Genome-wide genotyping array 104 2014-03-26 24025145 Chung S 2013-09-11 Breast Cancer Res www.ncbi.nlm.nih.gov/pubmed/24025145 A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients. Adverse response to chemotherapy in breast cancer (alopecia) (anti-microtubule) 119 Japanese ancestry cases, 105 Japanese ancestry controls NA Illumina [555600] 7 chemotherapy-induced alopecia, response to antimicrotubule agent http://www.ebi.ac.uk/efo/EFO_0005400, http://www.ebi.ac.uk/efo/EFO_0005260 GCST002177 Genome-wide genotyping array 224 2009-01-21 19132087 Burgner D 2009-01-09 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/19132087 A genome-wide association study identifies novel and functionally related susceptibility Loci for Kawasaki disease. Kawasaki disease 107 European ancestry cases, 134 European ancestry controls 583 European ancestry cases, 1,357 European ancestry controls from 583 families Affymetrix [223922] 2 mucocutaneous lymph node syndrome http://www.ebi.ac.uk/efo/EFO_0004246 GCST000314 Genome-wide genotyping array 241 2012-02-10 22267201 Stolk L 2012-01-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22267201 Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Menopause (age at onset) 38,968 European ancestry female individuals Up to 14,435 European ancestry female individuals Affymetrix, Illumina [2551160] (imputed) 19 age at menopause http://www.ebi.ac.uk/efo/EFO_0004704 GCST001381 Genome-wide genotyping array 38968 2014-03-18 23974872 Ripke S 2013-08-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23974872 Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Schizophrenia 5,001 European ancestry cases, 6,243 European ancestry controls, 8,832 cases, 12,067 controls 4,801 European ancestry cases, 4,741 European ancestry controls, 2,612 European and unknown ancestry cases, 15,021 European and unknown ancestry controls, 581 trios Affymetrix, Illumina [9871789] 27 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST002149 Genome-wide genotyping array 32143 2012-02-23 22286173 Low SK 2012-01-27 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22286173 Genome-wide association study for intracranial aneurysm in the Japanese population identifies three candidate susceptible loci and a functional genetic variant at EDNRA. Intracranial aneurysm 1,383 Japanese ancestry cases, 5,484 Japanese ancestry controls 1,048 Japanese ancestry cases, 7,212 Japanese ancestry controls Illumina [565149] 4 brain aneurysm http://www.ebi.ac.uk/efo/EFO_0003870 GCST001388 Genome-wide genotyping array 6867 2014-03-26 24001895 Kelly TN 2013-09-03 Hypertension www.ncbi.nlm.nih.gov/pubmed/24001895 Genome-wide association study meta-analysis reveals transethnic replication of mean arterial and pulse pressure loci. Blood pressure 22,275 East Asian ancestry individuals, 4,325 South East Asian ancestry individuals 28,783 East Asian ancestry individuals Affymetrix, Illumina [~ 2400000] (imputed) 6 blood pressure http://www.ebi.ac.uk/efo/EFO_0004325 GCST002167 Genome-wide genotyping array 26600 2010-05-23 20400778 Morrison AC 2010-04-17 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/20400778 Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium. Mortality in heart failure 1,645 European ancestry cases, 881 European ancestry controls, 281 African ancestry cases, 185 African ancestry controls NA Affymetrix [up to 2366858] (imputed) 11 mortality http://www.ebi.ac.uk/efo/EFO_0004352 GCST000661 Genome-wide genotyping array 2992 2011-11-08 21998595 N'Diaye A 2011-10-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21998595 Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. Height 20,427 African ancestry individuals Up to 16,436 African American individuals Affymetrix, Illumina [3310998] (imputed) 33 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST001263 Genome-wide genotyping array 20427 2012-04-03 22412388 Kenny EE 2012-03-08 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22412388 A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. Crohn's disease 737 Ashkenazi Jewish cases, 2,257 Ashkenazi Jewish controls 971 Ashkenazi Jewish cases, 2,124 Ashkenazi Jewish controls Affymetrix, Illumina [1060934] (imputed) 17 Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000384 GCST001438 Genome-wide genotyping array 2994 2011-07-30 21743057 Schumacher FR 2011-07-08 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21743057 Genome-wide association study identifies new prostate cancer susceptibility loci. Prostate cancer 2,782 European ancestry cases, 4,458 European ancestry controls 7,358 European ancestry cases, 6,732 European ancestry controls Illumina [571243] 14 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST001147 Genome-wide genotyping array 7240 2013-08-02 23502783 Weinhold N 2013-03-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23502783 The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma. Multiple myeloma (hyperdiploidy) up to 1,660 European ancestry cases, 7,306 European ancestry controls NA Illumina [414804] 14 multiple myeloma http://www.ebi.ac.uk/efo/EFO_0001378 GCST001907 Genome-wide genotyping array 8966 2013-08-02 23502783 Weinhold N 2013-03-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23502783 The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma. Multiple myeloma (IgH translocation) up to 1,660 European ancestry cases, 7,306 European ancestry controls NA Illumina [414804] (imputed) 25 multiple myeloma http://www.ebi.ac.uk/efo/EFO_0001378 GCST001906 Genome-wide genotyping array 8966 2011-06-01 21521612 Kohli MA 2011-04-28 Neuron www.ncbi.nlm.nih.gov/pubmed/21521612 The neuronal transporter gene SLC6A15 confers risk to major depression. Major depressive disorder 353 European ancestry cases, 366 European ancestry controls 991 African Americans, 4,308 European ancestry cases, 9,661 European ancestry controls Illumina [365676] 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST001056 Genome-wide genotyping array 719 2011-09-30 21900946 Nakabayashi K 2011-09-08 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/21900946 Identification of independent risk loci for Graves' disease within the MHC in the Japanese population. Graves' disease 1,119 Japanese ancestry cases, 2,718 Japanese ancestry controls 432 Japanese ancestry cases, 1,157 Japanese ancestry controls Perlegen [268068] 7 Graves disease http://www.ebi.ac.uk/efo/EFO_0004237 GCST001219 Genome-wide genotyping array 3837 2014-03-27 24124411 Park TJ 2013-09-30 Genomics Inform www.ncbi.nlm.nih.gov/pubmed/24124411 Genome-wide association study of liver enzymes in korean children. Liver enzyme levels (alanine transaminase) 484 Korean ancestry children NA Illumina [747076] 11 serum alanine aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004735 GCST002207 Genome-wide genotyping array 484 2014-03-27 24124411 Park TJ 2013-09-30 Genomics Inform www.ncbi.nlm.nih.gov/pubmed/24124411 Genome-wide association study of liver enzymes in korean children. Liver enzyme levels (aspartate transaminase) 484 Korean ancestry children NA Illumina [747076] 8 aspartate aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004736 GCST002208 Genome-wide genotyping array 484 2011-12-13 22032556 Brockschmidt FF 2011-10-27 Br J Dermatol www.ncbi.nlm.nih.gov/pubmed/22032556 Susceptibility variants on chromosome 7p21.1 suggest HDAC9 as a new candidate gene for male-pattern baldness. Male-pattern baldness 581 European ancestry male cases, 617 European ancestry male controls 461 European ancestry male cases, 151 European ancestry male controls Illumina [560387] 2 androgenetic alopecia http://www.ebi.ac.uk/efo/EFO_0004191 GCST001297 Genome-wide genotyping array 1198 2012-08-15 22581228 Manning AK 2012-05-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22581228 A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Fasting blood insulin (BMI interaction) Up to 51,750 European ancestry individuals Up to 33,823 European ancestry individuals Affymetrix, Illumina [~ 2400000] (imputed) 20 body mass index, fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004466 GCST001526 Genome-wide genotyping array 51750 2012-08-15 22581228 Manning AK 2012-05-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22581228 A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Fasting blood glucose (BMI interaction) Up to 58,074 European ancestry individuals Up tp 38,422 European ancestry individuals Affymetrix, Illumina [~ 2400000] (imputed) 33 body mass index, fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004465 GCST001527 Genome-wide genotyping array 58074 2018-01-25 22581228 Manning AK 2012-05-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22581228 A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Fasting blood insulin Up to 51,750 European ancestry individuals Up to 33,823 European ancestry individuals Affymetrix, Illumina [~ 2400000] (imputed) 10 fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004466 GCST005185 Genome-wide genotyping array 51750 2018-01-25 22581228 Manning AK 2012-05-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22581228 A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Fasting blood glucose Up to 58,074 European ancestry individuals Up tp 38,422 European ancestry individuals Affymetrix, Illumina [~ 2400000] (imputed) 33 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST005186 Genome-wide genotyping array 58074 2013-12-10 23740775 Xie G 2013-09-01 Arthritis Rheum www.ncbi.nlm.nih.gov/pubmed/23740775 Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis. Wegener's granulomatosis 459 European ancestry cases, 1,503 European ancestry controls 291 European ancestry cases, 317 European ancestry controls Illumina [287802] 5 Granulomatosis with Polyangiitis http://www.ebi.ac.uk/efo/EFO_0005297 GCST002160 Genome-wide genotyping array 1962 2013-12-10 23740775 Xie G 2013-09-01 Arthritis Rheum www.ncbi.nlm.nih.gov/pubmed/23740775 Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis. Wegener's granulomatosis 459 European ancestry cases, 1,503 European ancestry controls 528 European ancestry cases, 1,228 European ancestry controls Illumina [287802] 1 Granulomatosis with Polyangiitis http://www.ebi.ac.uk/efo/EFO_0005297 GCST002159 Genome-wide genotyping array 1962 2014-03-24 24080187 Guffanti G 2013-09-08 Psychoneuroendocrinology www.ncbi.nlm.nih.gov/pubmed/24080187 Genome-wide association study implicates a novel RNA gene, the lincRNA AC068718.1, as a risk factor for post-traumatic stress disorder in women. Post-traumatic stress disorder 81 African American female cases, 261 African American female controls, 10 European ancestry female cases, 35 European ancestry female controls, 3 female cases, 22 female controls 578 European ancestry female cases, 1,963 European ancestry female controls Illumina [688890] 0 post-traumatic stress disorder http://www.ebi.ac.uk/efo/EFO_0001358 GCST002171 Genome-wide genotyping array 412 2015-06-22 25192705 Du M 2014-09-05 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/25192705 No evidence of gene-calcium interactions from genome-wide analysis of colorectal cancer risk. Colorectal cancer (calcium intake interaction) 9,006 European ancestry cases, 9,503 European ancestry controls NA NR [~ 2700000] (imputed) 3 calcium intake measurement, colorectal cancer http://www.ebi.ac.uk/efo/EFO_0006521, http://www.ebi.ac.uk/efo/EFO_0005842 GCST002596 Genome-wide genotyping array 18509 2010-09-17 20659327 Kariuki SN 2010-07-26 Arthritis Res Ther www.ncbi.nlm.nih.gov/pubmed/20659327 Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus. Serologic markers in systemic lupus erythematosus 44 European, African American, Hispanic American, and Asian American high IFN-alpha cases, 60 European, African American, Hispanic American, and Asian American low IFN-alpha cases 280 African American cases, 173 European ancestry cases, 85 Hispanic American cases Affymetrix [NR] 0 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST000739 Genome-wide genotyping array 104 2014-10-28 24569950 Hatemi PK 2014-02-26 Behav Genet www.ncbi.nlm.nih.gov/pubmed/24569950 Genetic influences on political ideologies: twin analyses of 19 measures of political ideologies from five democracies and genome-wide findings from three populations. Political ideology 11,388 European ancestry individuals from 6,758 families NA Illumina [> 269840] (imputed) 19 economic and social preference http://www.ebi.ac.uk/efo/EFO_0004827 GCST002372 Genome-wide genotyping array 18146 2013-02-06 23183491 Nishizawa D 2012-11-27 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/23183491 Genome-wide association study identifies a potent locus associated with human opioid sensitivity. Opioid sensitivity 118 Japanese ancestry individuals 235 Japanese ancestry individuals Illumina [295036] 1 response to opiate http://purl.obolibrary.org/obo/GO_0014072 GCST001751 Genome-wide genotyping array 118 2009-09-28 18067574 Butcher LM 2008-01-22 Genes Brain Behav www.ncbi.nlm.nih.gov/pubmed/18067574 Genome-wide quantitative trait locus association scan of general cognitive ability using pooled DNA and 500K single nucleotide polymorphism microarrays. General cognitive ability 458 European ancestry low General cognitive ability children, 402 European ancestry high General codnitive ability children 3,195 European ancestry children Affymetrix [449127] 0 intelligence http://www.ebi.ac.uk/efo/EFO_0004337 GCST000145 Genome-wide genotyping array 860 2009-06-04 19451621 Landers JE 2009-05-18 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/19451621 Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis 1,821 cases, 2,258 controls 538 cases, 556 controls Illumina [288357] 16 amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0000253 GCST000406 Genome-wide genotyping array 4079 2014-12-11 24908248 Walsh KM 2014-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24908248 Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk. Glioma (high-grade) 1,013 European ancestry cases, 6,595 European ancestry controls 631 European ancestry cases, 1,141 European ancestry controls Affymetrix, Illumina [2362330] (imputed) 3 central nervous system cancer http://www.ebi.ac.uk/efo/EFO_0000326 GCST002474 Genome-wide genotyping array 7608 2008-06-27 18519826 Uhl GR 2008-06-04 Arch Gen Psychiatry www.ncbi.nlm.nih.gov/pubmed/18519826 Molecular genetics of successful smoking cessation: convergent genome-wide association study results. Smoking cessation 241 European ancestry successful abstainers, 309 European ancestry unsuccessful abstainers NA Affymetrix [~ 500000] 0 smoking cessation http://www.ebi.ac.uk/efo/EFO_0004319 GCST000203 Genome-wide genotyping array 550 2015-04-01 25027320 Ramirez A 2014-07-15 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/25027320 SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease. Cerebrospinal AB1-42 levels in Alzheimer's disease dementia 363 European ancestry individuals 515 individuals Illumina [6812394] (imputed) 2 beta-amyloid 1-42 measurement http://www.ebi.ac.uk/efo/EFO_0004670 GCST002531 Genome-wide genotyping array 363 2011-08-20 21804549 Torgerson DG 2011-07-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21804549 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Asthma 2,088 European ancestry cases, 1,612 African American and African Caribbean cases, 1,688 Hispanic cases 2,727 European ancestry cases, 2,147 African American and African Caribbean cases, 2,299 Hispanic cases Affymetrix, Illumina [> 2000000] (imputed) 7 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST001182 Genome-wide genotyping array 5388 2015-05-26 25158072 Yu D 2014-10-31 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/25158072 Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD. Tourette's syndrome or obsessive-compulsive disorder 1,310 Ashkenazi Jewish, South African Afrikaner ancestry, and other European ancestry OCD cases, 834 Ashkenazi Jewish, French Canadian and other European ancestry Tourette's Syndrome cases, 579 Ashkenazi Jewish, South African Afrikaner ancestry, French Canadian and other European ancestry OCD and Tourette's syndrome cases, 4,975 European ancestry controls, 338 Ashkenazi Jewish controls, 196 French Canadian controls, 158 South African Afrikaner ancestry controls, 290 European ancestry OCD parent-child trios NA Illumina [7659573] (imputed) 15 obsessive-compulsive disorder, Tourette syndrome http://www.ebi.ac.uk/efo/EFO_0004242, http://www.ebi.ac.uk/efo/EFO_0004895 GCST002682 Genome-wide genotyping array 8680 2009-02-26 19117981 Sun J 2009-01-01 Cancer Res www.ncbi.nlm.nih.gov/pubmed/19117981 Sequence variants at 22q13 are associated with prostate cancer risk. Prostate cancer 1,235 European ancestry aggressive cases, 1,599 European ancestry controls 1,215 European ancestry aggressive cases, 2,213 European ancestry non-aggressive cases, 1,208 European ancestry controls, 1,034 aggressive cases, 921 non-aggressive cases, 2,231 controls Affymetrix, Illumina [~ 2000000] (imputed) 1 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST000307 Genome-wide genotyping array 2834 2013-01-15 23108145 Wang LE 2012-10-29 Cancer Res www.ncbi.nlm.nih.gov/pubmed/23108145 Genome-wide association study reveals novel genetic determinants of DNA repair capacity in lung cancer. Lung Cancer (DNA repair capacity) 914 European ancestry non-small cell lung cancer cases, 860 European ancestry controls 679 European ancestry ancestry non-small cell lung cancer cases, 695 European ancestry controls Illumina [303669] 2 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST001721 Genome-wide genotyping array 1774 2015-09-22 25524241 Richter HE 2014-12-15 J Urol www.ncbi.nlm.nih.gov/pubmed/25524241 Genetic contributions to urgency urinary incontinence in women. Urgency urinary incontinence 1,102 European ancestry cases, 405 European ancestry controls 1,133 European ancestry cases, 371 European ancestry controls Illumina [9077347] (imputed) 6 urgency urinary incontinence http://www.ebi.ac.uk/efo/EFO_0006865 GCST002723 Genome-wide genotyping array 1507 2015-06-25 25293881 Patel YM 2014-10-07 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/25293881 The contribution of common genetic variation to nicotine and cotinine glucuronidation in multiple ethnic/racial populations. Cotinine glucuronidation 437 European ancestry current smoker individuals, 364 African American current smoker individuals, 453 Latino current smoker individuals, 674 Japanese ancestry current smoker individuals, 311 Native Hawaiian ancestry current smoker individuals NA Illumina [11892802] (imputed) 14 cotinine glucuronidation measurement http://www.ebi.ac.uk/efo/EFO_0006508 GCST002652 Genome-wide genotyping array 2239 2015-06-26 25293881 Patel YM 2014-10-07 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/25293881 The contribution of common genetic variation to nicotine and cotinine glucuronidation in multiple ethnic/racial populations. Nicotine glucouronidation 437 European ancestry current smoker individuals, 364 African American current smoker individuals, 453 Latino current smoker individuals, 674 Japanese ancestry current smoker individuals, 311 Native Hawaiian ancestry current smoker individuals NA Illumina [11892802] (imputed) 2 nicotine glucuronidation measurement http://www.ebi.ac.uk/efo/EFO_0006507 GCST002649 Genome-wide genotyping array 2239 2014-12-18 24945404 Kemp JP 2014-06-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/24945404 Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment. Bone mineral density (paediatric, upper limb) 8,007 European ancestry children, 289 Surinamese ancestry children, 300 Turkish ancestry children, 232 Moroccan ancestry children, 588 children NA Illumina [~ 2500000] (imputed) 11 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST002496 Genome-wide genotyping array 9416 2014-12-18 24945404 Kemp JP 2014-06-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/24945404 Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment. Bone mineral density (paediatric, total body less head) 8,007 European ancestry children, 289 Surinamese ancestry children, 300 Turkish ancestry children, 232 Moroccan ancestry children, 588 children NA Illumina [~ 2500000] (imputed) 15 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST002494 Genome-wide genotyping array 9416 2014-12-18 24945404 Kemp JP 2014-06-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/24945404 Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment. Bone mineral density (paediatric, lower limb) 8,007 European ancestry children, 289 Surinamese ancestry children, 300 Turkish ancestry children, 232 Moroccan ancestry children, 588 children NA Illumina [~ 2500000] (imputed) 11 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST002492 Genome-wide genotyping array 9416 2014-12-18 24945404 Kemp JP 2014-06-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/24945404 Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment. Bone mineral density (paediatric, skull) 7,976 European ancestry children, 289 Surinamese ancestry children, 300 Turkish ancestry children, 232 Moroccan ancestry children, 588 children NA Illumina [~ 2500000] (imputed) 19 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST002493 Genome-wide genotyping array 9385 2013-03-05 23181788 Lasky-Su J 2012-12-04 Clin Exp Allergy www.ncbi.nlm.nih.gov/pubmed/23181788 HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults. Asthma Up to 1,238 European ancestry cases, up to 2,617 European ancestry controls Up to 1,837 European ancestry cases, up to 3,803 European ancestry controls, up to 2,806 cases, up to 2,150 controls, up to 603 Costa Rican ancestry cases and their parents Affymetrix [455089] 1 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST001763 Genome-wide genotyping array 3855 2014-04-05 24084763 Wang J 2013-10-01 Clin Cancer Res www.ncbi.nlm.nih.gov/pubmed/24084763 Germline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study. Colorectal adenoma (advanced) 139 European ancestry cases, 1,267 European ancestry controls 4,175 European ancestry cases, 5,036 European ancestry controls Illumina [NR] 0 colorectal adenoma http://www.ebi.ac.uk/efo/EFO_0005406 GCST002212 Genome-wide genotyping array 1406 2014-02-08 23897914 Wang H 2013-07-29 Pediatrics www.ncbi.nlm.nih.gov/pubmed/23897914 A genome-wide association study (GWAS) for bronchopulmonary dysplasia. Bronchopulmonary dysplasia 117 African American newborn cases, 108 African American newborn controls, 448 Hispanic newborn cases, 460 Hispanic newborn controls, 74 Asian or Pacific Islander ancestry newborn cases, 93 Asian or Pacific Islander ancestry newborn controls, 174 European ancestry newborn cases, 216 European ancestry newborn controls, 14 newborn cases, 22 newborn controls 371 newborn cases, 424 newborn controls Illumina [1795103] 26 Bronchopulmonary dysplasia http://www.orpha.net/ORDO/Orphanet_70589 GCST002104 Genome-wide genotyping array 1726 2015-05-11 25055868 Sano M 2014-07-23 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/25055868 Genome-wide association study of electrocardiographic parameters identifies a new association for PR interval and confirms previously reported associations. Electrocardiographic traits 2,994 Japanese ancestry individuals 6,805 Korean ancestry individuals Illumina [~ 2500000] 9 electrocardiography http://www.ebi.ac.uk/efo/EFO_0004327 GCST002542 Genome-wide genotyping array 2994 2009-10-05 19772629 Latourelle JC 2009-09-22 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/19772629 Genomewide association study for onset age in Parkinson disease. Parkinson's disease (age of onset) 857 European ancestry familial cases, 440 idiopathic cases 747 European ancestry idiopathic cases Illumina, Perlegen [1861750] (imputed) 5 Parkinson's disease, age at onset http://www.ebi.ac.uk/efo/EFO_0002508, http://www.ebi.ac.uk/efo/EFO_0004847 GCST000490 Genome-wide genotyping array 1297 2014-02-10 21964575 Rafnar T 2011-10-02 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21964575 Mutations in BRIP1 confer high risk of ovarian cancer. Ovarian cancer 640 European ancestry cases, 41,607 European ancestry controls NA Illumina [15957390] (imputed) 1 ovarian carcinoma http://www.ebi.ac.uk/efo/EFO_0001075 GCST001258 Genome-wide genotyping array 42247 2014-12-05 24842889 Vacic V 2014-05-19 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/24842889 Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes. Parkinson's disease 1,130 Ashkenazi Jewish cases, 2,611 Ashkenazi Jewish controls 306 Ashkenazi Jewish cases, 2,583 Ashkenazi Jewish controls Affymetrix, Illumina [1069161] (imputed) 4 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST002455 Genome-wide genotyping array 3741 2015-09-22 25517131 Dijkstra AE 2015-02-27 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/25517131 Novel genes for airway wall thickness identified with combined genome-wide association and expression analyses. Airway wall thickness 2,640 individuals up to 714 individuals Illumina [522636] 19 airway wall thickness measurement http://www.ebi.ac.uk/efo/EFO_0006898 GCST002794 Genome-wide genotyping array 2640 2014-12-16 24934506 Eny KM 2014-06-17 Diabetologia www.ncbi.nlm.nih.gov/pubmed/24934506 GWAS identifies an NAT2 acetylator status tag single nucleotide polymorphism to be a major locus for skin fluorescence. Skin fluorescence 1,082 European ancestry individuals with type 1 diabetes, 8,721 European ancestry individuals 202 European ancestry individuals with type 1 diabetes, 318 European ancestry individuals with type 2 diabetes, 515 European ancestry individuals Illumina [up to 1609583] (imputed) 0 skin fluorescence measurement http://www.ebi.ac.uk/efo/EFO_0005766 GCST002484 Genome-wide genotyping array 9804 2014-08-02 24388013 Ferreira MA 2013-12-30 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/24388013 Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. Asthma and hay fever 6,685 European ancestry cases, 14,091 European ancestry controls 878 European ancestry cases, 2,455 European ancestry controls Illumina [up to 4972397] (imputed) 21 seasonal allergic rhinitis, asthma http://www.ebi.ac.uk/efo/EFO_0003956, http://www.ebi.ac.uk/efo/EFO_0000270 GCST002322 Genome-wide genotyping array 20776 2013-01-11 23104006 Nyholt DR 2012-10-28 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23104006 Genome-wide association meta-analysis identifies new endometriosis risk loci. Endometriosis 3,181 European ancestry cases, 8,075 European ancestry controls, 1,423 Japanese ancestry cases, 1,318 Japanese ancestry controls 1,044 Japanese ancestry, 4,017 Japanese ancestry controls Illumina [407632] 7 endometriosis http://www.ebi.ac.uk/efo/EFO_0001065 GCST001720 Genome-wide genotyping array 13997 2009-01-16 19115949 Limou S 2009-01-01 J Infect Dis www.ncbi.nlm.nih.gov/pubmed/19115949 Genomewide association study of an AIDS-nonprogression cohort emphasizes the role played by HLA genes (ANRS Genomewide Association Study 02). AIDS progression 275 European ancestry seropositive non-progressors, 86 European ancestry seropositive rapid progressors, 1,352 European ancestry seronegative controls (see Fellay 2007) Illumina [291119] 3 AIDS http://www.ebi.ac.uk/efo/EFO_0000765 GCST000308 Genome-wide genotyping array 1713 2011-08-18 21771975 Chung CM 2011-07-19 Diabetes www.ncbi.nlm.nih.gov/pubmed/21771975 A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes. Adiponectin levels 382 Han Chinese ancestry young-onset-hypertensive cases 559 Han Chinese ancestry young-onset-hypertensive cases Illumina [509174] 1 adiponectin measurement http://www.ebi.ac.uk/efo/EFO_0004502 GCST001165 Genome-wide genotyping array 382 2014-12-13 24929828 Loth DW 2014-06-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24929828 Genome-wide association analysis identifies six new loci associated with forced vital capacity. Lung function (forced vital capacity) 52,253 European ancestry indiviudals 32,917 European ancestry individuals, 6,070 African American individuals, 849 Hispanic individuals, 8,637 East Asian ancestry individuals Affymetrix, Illumina [2762059] (imputed) 7 vital capacity http://www.ebi.ac.uk/efo/EFO_0004312 GCST002483 Genome-wide genotyping array 52253 2014-04-11 24513584 Oei L 2013-10-25 Bone www.ncbi.nlm.nih.gov/pubmed/24513584 Genome-wide Association Study for Radiographic Vertebral Fractures: A Potential Role for the 16q24 BMD Locus versus Lessons Learned from Challenging Phenotype Definition. Fractures (vertebral) 329 European ancestry cases, 2,666 European ancestry controls 5,619 European ancestry cases, 20,598 European ancestry controls, 101 Korean ancestry cases, 1,193 Korean ancestry controls Illumina [2543887] (imputed) 0 spinal fracture http://www.ebi.ac.uk/efo/EFO_0003902 GCST002244 Genome-wide genotyping array 2995 2015-09-22 25461247 Lehmann DS 2015-02-01 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/25461247 Genome-wide association study of virologic response with efavirenz-containing or abacavir-containing regimens in AIDS clinical trials group protocols. Response to efavirenz-containing treatment in HIV 1 infection (virologic failure) Up to 737 European ancestry individuals, Up to 545 Black individuals, Up to 314 Hispanic individuals NA Illumina [> 8000000] (imputed) 35 response to efavirenz, virologic response measurement http://www.ebi.ac.uk/efo/EFO_0006904, http://www.ebi.ac.uk/efo/EFO_0006906 GCST002771 Genome-wide genotyping array 1596 2015-09-21 25461247 Lehmann DS 2015-02-01 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/25461247 Genome-wide association study of virologic response with efavirenz-containing or abacavir-containing regimens in AIDS clinical trials group protocols. Response to abacavir-containing treatment in HIV-1 infection (virologic failure) Up 346 European ancestry individuals, Up to 265 Black individuals, Up to 175 Hispanic individuals NA Illumina [> 8000000] (imputed) 27 virologic response measurement, response to abacavir http://www.ebi.ac.uk/efo/EFO_0006906, http://www.ebi.ac.uk/efo/EFO_0006905 GCST002769 Genome-wide genotyping array 786 2012-11-28 22945461 Rahmioglu N 2012-09-04 Eur J Drug Metab Pharmacokinet www.ncbi.nlm.nih.gov/pubmed/22945461 Genome-wide association study reveals a complex genetic architecture underpinning-induced CYP3A4 enzyme activity. CYP3A4 enzyme activity 310 European ancestry female twin individuals NA Illumina [NR] 0 CYP3A4 activity http://www.ebi.ac.uk/efo/EFO_0004910 GCST001661 Genome-wide genotyping array 310 2013-03-19 23222517 van der Harst P 2012-12-05 Nature www.ncbi.nlm.nih.gov/pubmed/23222517 Seventy-five genetic loci influencing the human red blood cell. Red blood cell traits 62,553 European ancestry individuals, 9,308 South Asian ancestry individuals 63,506 European ancestry individuals Affymetrix, Illumina, Perlegen [2711806] (imputed) 45 erythrocyte measurement http://www.ebi.ac.uk/efo/EFO_0005047 GCST001765 Genome-wide genotyping array 71861 2015-05-15 21368711 Alliey-Rodriguez N 2011-03-02 Psychiatr Genet www.ncbi.nlm.nih.gov/pubmed/21368711 Genome-wide association study of personality traits in bipolar patients. Personality traits in bipolar disorder 1,951 European ancestry cases NA Affymetrix [702866] 7 personality trait http://www.ebi.ac.uk/efo/EFO_0004365 GCST000995 Genome-wide genotyping array 1951 2015-09-22 25475840 Colodro-Conde L 2014-12-05 Twin Res Hum Genet www.ncbi.nlm.nih.gov/pubmed/25475840 A twin study of breastfeeding with a preliminary genome-wide association scan. Breastfeeding duration 1,521 mothers from 1,073 families NA Illumina [6590000] (imputed) 9 breastfeeding duration http://www.ebi.ac.uk/efo/EFO_0006864 GCST002715 Genome-wide genotyping array 2594 2015-05-07 25108383 Geller F 2014-08-10 Nat Genet www.ncbi.nlm.nih.gov/pubmed/25108383 Genome-wide association analyses identify variants in developmental genes associated with hypospadias. Hypospadias 1,006 European ancestry male child cases, 2,390 European ancestry male child controls, 3,096 European ancestry female child controls 1,972 European ancestry male child cases, 1,401 European ancestry male child controls, 405 European ancestry female child controls, 6 European ancestry child controls Illumina [8207076] (imputed) 24 hypospadias http://www.ebi.ac.uk/efo/EFO_0004209 GCST002563 Genome-wide genotyping array 6492 2015-05-07 25208829 Anderson D 2014-09-11 Genes Immun www.ncbi.nlm.nih.gov/pubmed/25208829 Genome-wide association study of vitamin D levels in children: replication in the Western Australian Pregnancy Cohort (Raine) study. Vitamin D levels 645 European ancestry age 6 individuals, 28 age 6 individuals, 1,073 European ancestry age 14 individuals, 67 age 14 individuals NA Illumina [2461244] (imputed) 11 vitamin D measurement http://www.ebi.ac.uk/efo/EFO_0004631 GCST002602 Genome-wide genotyping array 1853 2015-07-17 24931836 Diekstra FP 2014-06-27 Ann Neurol www.ncbi.nlm.nih.gov/pubmed/24931836 C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis. Amyotrophic lateral sclerosis or frontotemporal dementia 4,377 European ancestry ALS cases, 435 European ancestry FTD cases, 14,431 European ancestry controls 4,056 European ancestry ALS cases, 3,958 European ancestry controls Illumina [~ 1400000] (imputed) 1 amyotrophic lateral sclerosis, Frontotemporal dementia http://www.ebi.ac.uk/efo/EFO_0000253, http://www.orpha.net/ORDO/Orphanet_282 GCST002510 Genome-wide genotyping array 19243 2015-07-17 24931836 Diekstra FP 2014-06-27 Ann Neurol www.ncbi.nlm.nih.gov/pubmed/24931836 C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis. Frontotemporal dementia 435 European ancestry cases, 1,414 European ancestry controls NA Illumina [~ 1400000] (imputed) 1 Frontotemporal dementia http://www.orpha.net/ORDO/Orphanet_282 GCST002508 Genome-wide genotyping array 1849 2015-09-22 24931836 Diekstra FP 2014-06-27 Ann Neurol www.ncbi.nlm.nih.gov/pubmed/24931836 C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis. Amyotrophic lateral sclerosis 4,377 European ancestry cases, 13,017 European ancestry controls NA Illumina [~ 1400000] (imputed) 6 amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0000253 GCST002509 Genome-wide genotyping array 17394 2014-07-28 24322204 Winham SJ 2013-12-10 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/24322204 Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2. Bipolar disorder (body mass index interaction) 388 European ancestry cases, 1,020 European ancestry controls NA NR [up to 8466825] (imputed) 51 bipolar disorder, body mass index http://www.ebi.ac.uk/efo/EFO_0000289, http://www.ebi.ac.uk/efo/EFO_0004340 GCST002306 Genome-wide genotyping array 1408 2015-07-07 25372704 Mtatiro SN 2014-11-05 PLoS One www.ncbi.nlm.nih.gov/pubmed/25372704 Genome wide association study of fetal hemoglobin in sickle cell anemia in Tanzania. Fetal hemoglobin levels in sickle cell anemia 1,213 Tanzanian ancestry cases 321 Afro-Caribbean and Sub-Saharan African cases Illumina [15153765] (imputed) 2 fetal hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004576 GCST002687 Genome-wide genotyping array 1213 2010-03-09 20164292 Koller DL 2010-02-17 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/20164292 Genome-wide association study of bone mineral density in premenopausal European-American women and replication in African-American women. Bone mineral density 1,524 European ancestry female individuals from 762 sibships 669 African American female individuals from 383 sibships Illumina [547971] 0 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST000598 Genome-wide genotyping array 2286 2015-12-04 25584925 Chen W 2015-01-13 Ann Am Thorac Soc www.ncbi.nlm.nih.gov/pubmed/25584925 A genome-wide association study of chronic obstructive pulmonary disease in Hispanics. Chronic obstructive pulmonary disease 94 Costa Rican founder population smoker cases, 412 Costa Rican founder population smoker controls, 63 Hispanic ancestry cases, 619 Hispanic ancestry controls 47 Hispanic ancestry smoker cases, 290 Hispanic ancestry smoker controls Affymetrix, Illumina [~ 2600000] (imputed) 3 chronic obstructive pulmonary disease http://www.ebi.ac.uk/efo/EFO_0000341 GCST002750 Genome-wide genotyping array 1188 2014-11-01 24684796 Cox AJ 2014-03-11 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/24684796 Heritability and genetic association analysis of cognition in the Diabetes Heart Study. Cognitive function 423 type 2 diabetes cases and 127 unaffected siblings from 257 families NA Affymetrix [> 371951] (imputed) 25 cognition http://www.ebi.ac.uk/efo/EFO_0003925 GCST002386 Genome-wide genotyping array 809 2014-11-13 24722205 Kwak SH 2014-04-17 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/24722205 A genome-wide association study on thyroid function and anti-thyroid peroxidase antibodies in Koreans. Free thyroxine concentration 2,789 Korean ancestry individuals 829 Korean ancestry individuals Affymetrix [1418709] (imputed) 3 thyroxine measurement http://www.ebi.ac.uk/efo/EFO_0005130 GCST002418 Genome-wide genotyping array 2789 2014-11-13 24722205 Kwak SH 2014-04-17 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/24722205 A genome-wide association study on thyroid function and anti-thyroid peroxidase antibodies in Koreans. Thyroid peroxidase antibody positivity 377 Korean ancestry cases, 3,019 Korean ancestry anti-TPO controls 108 Korean ancestry cases, 734 Korean ancestry controls Affymetrix [1418709] (imputed) 2 thyroid peroxidase antibody measurement http://www.ebi.ac.uk/efo/EFO_0005666 GCST002416 Genome-wide genotyping array 3396 2014-11-13 24722205 Kwak SH 2014-04-17 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/24722205 A genome-wide association study on thyroid function and anti-thyroid peroxidase antibodies in Koreans. Plasma thyroid-stimulating hormone levels 2,789 Korean ancestry individuals 829 Korean ancestry individuals Affymetrix [1418709] (imputed) 3 thyroid stimulating hormone measurement http://www.ebi.ac.uk/efo/EFO_0004748 GCST002417 Genome-wide genotyping array 2789 2014-11-26 24871463 Armstrong DL 2014-05-29 Genes Immun www.ncbi.nlm.nih.gov/pubmed/24871463 GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region. Systemic lupus erythematosus 725 European ancestry cases, 2,438 European ancestry controls NA Illumina [NR] 25 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST002463 Genome-wide genotyping array 3163 2012-11-22 22899653 Timofeeva MN 2012-08-16 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22899653 Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. Lung cancer up to 14,900 European ancestry cases, up to 29,485 European ancestry controls 2,338 Han Chinese ancestry cases, 3,077 Han Chinese ancestry controls Illumina [up to 536008] 1 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST001638 Genome-wide genotyping array 44385 2012-12-21 23031429 Surakka I 2012-10-03 Twin Res Hum Genet www.ncbi.nlm.nih.gov/pubmed/23031429 A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol. Apolipoprotein Levels 1,720 European ancestry monozygotic twins NA Illumina [~ 2500000] (imputed) 3 lipoprotein measurement http://www.ebi.ac.uk/efo/EFO_0004732 GCST001703 Genome-wide genotyping array 1720 2012-12-21 23031429 Surakka I 2012-10-03 Twin Res Hum Genet www.ncbi.nlm.nih.gov/pubmed/23031429 A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol. Cholesterol and Triglycerides 1,720 European ancestry monozygotic twins 1,261 European ancestry monozygotic twins Illumina [~ 2500000] (imputed) 1 triglyceride measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0004612 GCST001704 Genome-wide genotyping array 1720 2015-05-09 25064009 Nalls MA 2014-07-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/25064009 Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease. Parkinson's disease 13,708 European ancestry cases, 95,282 European ancestry controls 5,353 European ancestry cases, 5,551 European ancestry controls Illumina [7893274] (imputed) 26 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST002544 Genome-wide genotyping array 108990 2010-03-02 20125088 Shi J 2010-02-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/20125088 Genome-wide association study of recurrent early-onset major depressive disorder. Major depressive disorder 1,020 European ancestry cases, 1,636 European ancestry controls NA Affymetrix [671424] 9 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST000578 Genome-wide genotyping array 2656 2014-10-28 24656865 Woo D 2014-03-18 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/24656865 Meta-analysis of genome-wide association studies identifies 1q22 as a susceptibility locus for intracerebral hemorrhage. Intracerebral hemorrhage 664 European ancestry lobar cases, 881 European ancestry nonlobar cases, 1,481 European ancestry controls 513 European ancestry cases, 634 African American cases, 534 Hispanic cases, 1,552 European ancestry controls, 449 African American controls, 260 Hispanic controls Affymetrix, Illumina [5258103] (imputed) 1 intracerebral hemorrhage http://www.ebi.ac.uk/efo/EFO_0005669 GCST002389 Genome-wide genotyping array 3026 2015-02-20 24939585 Fransen E 2014-06-18 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/24939585 Genome-wide association analysis demonstrates the highly polygenic character of age-related hearing impairment. Age-related hearing impairment 1,489 European ancestry individuals NA Illumina [4167292] (imputed) 30 age-related hearing impairment http://www.ebi.ac.uk/efo/EFO_0005782 GCST002491 Genome-wide genotyping array 1489 2015-02-20 24939585 Fransen E 2014-06-18 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/24939585 Genome-wide association analysis demonstrates the highly polygenic character of age-related hearing impairment. Age-related hearing impairment (SNP x SNP interaction) 1,489 European ancestry individuals NA Illumina [629437] (imputed) 49 age-related hearing impairment http://www.ebi.ac.uk/efo/EFO_0005782 GCST002487 Genome-wide genotyping array 1489 2014-08-02 24347629 Shaffer JR 2013-12-17 G3 (Bethesda) www.ncbi.nlm.nih.gov/pubmed/24347629 Genome-wide association study of periodontal health measured by probing depth in adults ages 18-49 years. Periodontal disease-related phenotype (Socransky) 93 European ancestry cases, 83 European ancestry individuals, 497 European ancestry controls NA Illumina [~ 1400000] (imputed) 10 periodontitis http://www.ebi.ac.uk/efo/EFO_0000649 GCST002312 Genome-wide genotyping array 673 2009-11-30 19875103 Aberg K 2009-10-27 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/19875103 Genomewide association study of movement-related adverse antipsychotic effects. Response to antipsychotic therapy (extrapyramidal side effects) 421 European ancestry schizophrenia cases, 214 African American schizophrenia cases, 103 schizophrenia cases NA Affymetrix [492000] 17 response to antipsychotic drug http://purl.obolibrary.org/obo/GO_0097332 GCST000514 Genome-wide genotyping array 738 2015-04-01 25017104 Kottyan LC 2014-07-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/25017104 Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease. Eosinophilic esophagitis 657 European ancestry cases, 9,296 European ancestry controls NA Illumina [1468075] 17 eosinophilic esophagitis http://www.ebi.ac.uk/efo/EFO_0004232 GCST002527 Genome-wide genotyping array 9953 2014-07-22 24244560 Chen P 2013-11-07 PLoS One www.ncbi.nlm.nih.gov/pubmed/24244560 A study assessing the association of glycated hemoglobin A1C (HbA1C) associated variants with HbA1C, chronic kidney disease and diabetic retinopathy in populations of Asian ancestry. Glycated hemoglobin levels 3,427 Chinese ancestry individuals, 1,735 Malay ancestry individuals, 1,520 Asian Indian ancestry individuals NA Illumina [up to 2400000] (imputed) 3 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST002270 Genome-wide genotyping array 6682 2014-12-10 24816252 Shin SY 2014-05-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24816252 An atlas of genetic influences on human blood metabolites. Blood metabolite ratios Up to 5,591 European ancestry individuals Up to 1,767 European ancestry individuals Affymetrix, Illumina [2100000] (imputed) 54 blood metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005664 GCST002442 Genome-wide genotyping array 5591 2014-12-10 24816252 Shin SY 2014-05-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24816252 An atlas of genetic influences on human blood metabolites. Blood metabolite levels 7,824 European ancestry individuals NA Affymetrix, Illumina [2100000] (imputed) 245 blood metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005664 GCST002443 Genome-wide genotyping array 7824 2014-06-26 24236485 Cornejo-Garcia JA 2013-11-01 Pharmacogenomics www.ncbi.nlm.nih.gov/pubmed/24236485 Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations. Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced) 112 European ancestry cases, 124 European ancestry controls, 120 Han Chinese ancestry cases, 101 Han Chinese ancestry controls NA Affymetrix [up to 644046] 9 response to non-steroidal anti-inflammatory, angioedema http://www.ebi.ac.uk/efo/EFO_0005533, http://www.ebi.ac.uk/efo/EFO_0005532 GCST002263 Genome-wide genotyping array 457 2015-07-07 25233373 Simpson CL 2014-09-18 PLoS One www.ncbi.nlm.nih.gov/pubmed/25233373 Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci. Hyperopia 7,068 European ancestry cases, 6,844 European ancestry controls 1,554 European ancestry cases, 892 cases, 1,654 European ancestry controls, 2,921 controls Affymetrix, Illumina [up to 3397980] (imputed) 5 Hypermetropia http://purl.obolibrary.org/obo/HP_0000540 GCST002617 Genome-wide genotyping array 13912 2015-07-07 25233373 Simpson CL 2014-09-18 PLoS One www.ncbi.nlm.nih.gov/pubmed/25233373 Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci. Myopia 3,923 European ancestry cases, 11,696 European ancestry controls 1,410 European ancestry cases, 2,921 cases, 3,171 European ancestry controls, 998 controls Affymetrix, Illumina [up to 3397980] (imputed) 4 Myopia http://purl.obolibrary.org/obo/HP_0000545 GCST002615 Genome-wide genotyping array 15619 2015-05-23 25224454 Li J 2014-09-15 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/25224454 Genome-wide admixture and association study of serum iron, ferritin, transferrin saturation and total iron binding capacity in African Americans. Iron status biomarkers 2,347 African American individuals 329 African American individuals Affymetrix [~ 17000000] (imputed) 3 iron biomarker measurement http://www.ebi.ac.uk/efo/EFO_0004461 GCST002609 Genome-wide genotyping array 2347 2015-04-01 25023989 Schmit SL 2014-07-14 Carcinogenesis www.ncbi.nlm.nih.gov/pubmed/25023989 A novel colorectal cancer risk locus at 4q32.2 identified from an international genome-wide association study. Colorectal cancer 485 Ashkenazi Jewish cases, 498 Ashkenazi Jewish controls, 1,977 European ancestry cases, 999 European ancestry controls 1,131 Ashkenazi Jewish cases, 831 Ashkenazi Jewish controls Illumina [up to 9177523] (imputed) 1 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST002528 Genome-wide genotyping array 3959 2014-11-19 24852370 Zhan M 2014-05-22 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/24852370 Genome-wide association study identifies a novel susceptibility gene for serum TSH levels in Chinese populations. Serum thyroid-stimulating hormone levels 1,346 Han Chinese ancestry individuals 3,235 She Chinese ancestry individuals Illumina [8503852] (imputed) 4 thyroid stimulating hormone measurement http://www.ebi.ac.uk/efo/EFO_0004748 GCST002458 Genome-wide genotyping array 1346 2010-11-30 20953186 Huffmeier U 2010-10-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20953186 Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis. Psoriatic arthritis 572 European ancestry cases, 888 European ancestry controls Up to 1,761 European ancestry cases, 3,727 European ancestry controls Affymetrix [1585307] (imputed) 3 psoriatic arthritis http://www.ebi.ac.uk/efo/EFO_0003778 GCST000835 Genome-wide genotyping array 1460 2015-05-27 25266886 Kim JJ 2014-09-30 Pediatr Cardiol www.ncbi.nlm.nih.gov/pubmed/25266886 Common variants in the CRP promoter are associated with a high C-reactive protein level in Kawasaki disease. Inflammatory biomarkers in Kawasaki disease 178 Korean ancestry cases 473 Korean ancestry cases Illumina [646914] 1 inflammatory biomarker measurement, C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004872, http://www.ebi.ac.uk/efo/EFO_0004458 GCST002640 Genome-wide genotyping array 178 2015-09-22 25305756 Kiryluk K 2014-10-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/25305756 Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens. IgA nephropathy 1,194 Han Chinese ancestry cases, 902 Han Chinese ancestry controls, 1,553 European ancestry cases, 3,050 European ancestry controls 2,491 East Asian ancestry cases, 1,780 East Asian ancestry controls, 2,420 European ancestry cases, 7,222 European ancestry controls Illumina [> 1000000] (imputed) 32 IGA glomerulonephritis http://www.ebi.ac.uk/efo/EFO_0004194 GCST002655 Genome-wide genotyping array 6699 2014-11-08 24700089 Miura K 2014-04-04 J Med Virol www.ncbi.nlm.nih.gov/pubmed/24700089 Genome-wide association study of HPV-associated cervical cancer in Japanese women. Cervical cancer 226 Japanese ancestry cases, 186 Japanese ancestry controls NA Affymetrix [556045] 9 cervical carcinoma http://www.ebi.ac.uk/efo/EFO_0001061 GCST002405 Genome-wide genotyping array 412 2015-01-20 24925725 Chung SA 2014-06-12 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/24925725 Lupus nephritis susceptibility loci in women with systemic lupus erythematosus. Lupus nephritis in systemic lupus erythematosus 588 European ancestry cases, 1,412 European ancestry controls NA Affymetrix, Illumina [1621689] (imputed) 17 lupus nephritis http://www.ebi.ac.uk/efo/EFO_0005761 GCST002479 Genome-wide genotyping array 2000 2015-04-28 24241537 Bonnelykke K 2013-11-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24241537 A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations. Asthma (childhood onset) 1,173 European ancestry cases, 2,511 European ancestry controls 395 European ancestry cases, 2,663 European ancestry controls, 63 Turkish, Surinamese, Dutch Antillean, Moroccan, Cape Verdian and other ancestry cases, 917 Turkish, Surinamese, Dutch Antillean, Moroccan, Cape Verdian and other ancestry controls, 6,783 cases, 7,720 controls Affymetrix, Illumina [124514] 6 childhood onset asthma http://www.ebi.ac.uk/efo/EFO_0004591 GCST002275 Genome-wide genotyping array 3684 2013-09-24 19901119 Trevino LR 2009-11-09 J Clin Oncol www.ncbi.nlm.nih.gov/pubmed/19901119 Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects. Methotrexate phramacokinetics (acute lymphoblastic leukemia) 315 European ancestry cases, 73 African American cases, 5 Asian ancestry cases, 247 cases NA Affymetrix [398699] 21 response to antineoplastic agent http://purl.obolibrary.org/obo/GO_0097327 GCST000523 Genome-wide genotyping array 640 2014-08-05 24390342 Okada Y 2013-12-25 Nature www.ncbi.nlm.nih.gov/pubmed/24390342 Genetics of rheumatoid arthritis contributes to biology and drug discovery. Rheumatoid arthritis up to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls up to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls Affymetrix, Illumina [up to 9739303] (imputed) 181 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST002318 Genome-wide genotyping array 79799 2012-12-06 23006423 Niu N 2012-09-24 BMC Cancer www.ncbi.nlm.nih.gov/pubmed/23006423 Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study. Response to taxane treatment (placlitaxel) 96 African American lymphoblastoid cell lines, 96 European ancestry lymphoblastoid cell lines, 96 Han Chinese ancestry lymphoblastoid cell lines NA Affymetrix, Illumina [~ 1300000] 13 response to paclitaxel http://purl.obolibrary.org/obo/GO_1901555 GCST001694 Genome-wide genotyping array 288 2012-12-06 23006423 Niu N 2012-09-24 BMC Cancer www.ncbi.nlm.nih.gov/pubmed/23006423 Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study. Response to taxane treatment (docetaxel) 96 African American lymphoblastoid cell lines, 96 European ancestry lymphoblastoid cell lines, 96 Han Chinese ancestry lymphoblastoid cell lines NA Affymetrix, Illumina [~ 1300000] 16 response to antineoplastic agent http://purl.obolibrary.org/obo/GO_0097327 GCST001692 Genome-wide genotyping array 288 2014-03-21 23989729 Feenstra B 2013-08-21 JAMA www.ncbi.nlm.nih.gov/pubmed/23989729 Plasma lipids, genetic variants near APOA1, and the risk of infantile hypertrophic pyloric stenosis. Infantile hypertrophic pyloric stenosis 1,001 European ancestry cases, 2,371 European ancestry controls 925 European ancestry cases, 1,621 European ancestry controls, 738 cases, 697 controls Illumina [9737928] (imputed) 4 infantile hypertrophic pyloric stenosis http://www.ebi.ac.uk/efo/EFO_0004707 GCST002145 Genome-wide genotyping array 3372 2014-03-13 23955597 Chubb D 2013-08-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23955597 Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk. Multiple myeloma 2,335 European ancestry cases, 7,306 European ancestry controls 2,357 European ancestry cases, 3,684 European ancestry controls Illumina [414804] 6 multiple myeloma http://www.ebi.ac.uk/efo/EFO_0001378 GCST002140 Genome-wide genotyping array 9641 2014-03-22 24029427 Sandholm N 2013-09-12 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/24029427 Chromosome 2q31.1 associates with ESRD in women with type 1 diabetes. End-stage renal disease in Type 1 diabetics 258 European ancestry female cases, 935 European ancestry female controls, 387 European ancestry male cases, 655 European ancestry male controls 178 European ancestry female cases, 594 European ancestry female controls, 251 European ancestry male cases, 494 European ancestry male controls, 252 female cases, 479 female controls, 256 male cases, 342 male controls Illumina [2400000] (imputed) 1 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST002182 Genome-wide genotyping array 2235 2011-11-18 21993531 Kuparinen T 2011-10-13 Genes Immun www.ncbi.nlm.nih.gov/pubmed/21993531 Genome-wide association study does not reveal major genetic determinants for anti-cytomegalovirus antibody response. Cytomegalovirus antibody response 1,485 European ancestry sero-postitive individuals, 648 European ancestry sero-negative individuals NA Illumina [546677] 9 response to virus http://purl.obolibrary.org/obo/GO_0009615 GCST001272 Genome-wide genotyping array 2133 2012-12-21 23056639 de Boer RA 2012-10-09 PLoS One www.ncbi.nlm.nih.gov/pubmed/23056639 A genome-wide association study of circulating galectin-3. Protein biomarker 3,776 European ancestry individuals 3,516 individuals Illumina [2269099] (imputed) 2 protein measurement http://www.ebi.ac.uk/efo/EFO_0004747 GCST001711 Genome-wide genotyping array 3776 2015-04-23 25231870 Perry JR 2014-07-23 Nature www.ncbi.nlm.nih.gov/pubmed/25231870 Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Menarche (age at onset) Up to 182,413 European ancestry females NA Affymetrix, Illumina [2441815] (imputed) 122 age at menarche http://www.ebi.ac.uk/efo/EFO_0004703 GCST002541 Genome-wide genotyping array 182413 2014-11-14 24782177 Jiang L 2014-05-01 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/24782177 Novel risk loci for rheumatoid arthritis in Han Chinese and congruence with risk variants in Europeans. Rheumatoid arthritis 433 Han Chinese ancestry ACPA positive cases, 519 Han Chinese ancestry ACPA negative cases, 943 Han Chinese ancestry controls 1,032 Han Chinese ancestry ACPA positive cases, 1,100 Han Chinese ancestry ACPA negative cases, 2,553 Han Chinese ancestry controls Affymetrix [3441843] (imputed) 11 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST002433 Genome-wide genotyping array 1895 2014-11-14 24782177 Jiang L 2014-05-01 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/24782177 Novel risk loci for rheumatoid arthritis in Han Chinese and congruence with risk variants in Europeans. Rheumatoid arthritis 952 Han Chinese ancestry cases, 943 Han Chinese ancestry controls 5,539 European ancestry cases, 20,169 European ancestry controls Affymetrix [1497047] (imputed) 4 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST002434 Genome-wide genotyping array 1895 2014-01-08 23817571 Bonnelykke K 2013-06-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23817571 Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization. Allergic sensitization 5,789 European ancestry cases, 10,056 European ancestry controls 6,114 European ancestry cases, 9,920 European ancestry controls Affymetrix, Illumina [~ 2500000] (imputed) 12 allergic sensitization measurement http://www.ebi.ac.uk/efo/EFO_0005298 GCST002084 Genome-wide genotyping array 15845 2013-09-06 19954339 Yin CS 2009-12-01 J Altern Complement Med www.ncbi.nlm.nih.gov/pubmed/19954339 Genome-wide association study of the four-constitution medicine. Sasang constitutional medicine type 60 Korean ancestry individuals NA Illumina [353202] 0 Sasang constitutional medicine http://www.ebi.ac.uk/efo/EFO_0004892 GCST000536 Genome-wide genotyping array 60 2013-09-24 19936222 Chasman DI 2009-11-20 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/19936222 Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis. Lipid metabolism phenotypes Up to 17,296 European ancestry female individuals Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls Illumina [335603] 73 lipid measurement http://www.ebi.ac.uk/efo/EFO_0004529 GCST000533 Genome-wide genotyping array 17296 2015-06-26 25344690 Feenstra B 2014-10-26 Nat Genet www.ncbi.nlm.nih.gov/pubmed/25344690 Common variants associated with general and MMR vaccine-related febrile seizures. Febrile seizures 929 European ancestry MMR vaccine-related febrile seizures cases, 1,070 European ancestry MMR vaccine-unrelated febrile seizures cases, 4,118 European ancestry controls Up to 408 European ancestry MMR vaccine-related febrile seizures cases, Up to 1,034 European ancestry MMR vaccine-unrelated febrile seizures cases, Up to 1,645 European ancestry controls Illumina [up to 8129553] (imputed) 7 Febrile seizure (within the age range of 3 months to 6 years) http://purl.obolibrary.org/obo/HP_0002373 GCST002672 Genome-wide genotyping array 6117 2015-06-26 25344690 Feenstra B 2014-10-26 Nat Genet www.ncbi.nlm.nih.gov/pubmed/25344690 Common variants associated with general and MMR vaccine-related febrile seizures. Febrile seizures (MMR vaccine-unrelated) 1,070 European ancestry cases, 4,118 European ancestry controls Up to 1,034 European ancestry cases, Up to 1,645 European ancestry controls Illumina [8129384] (imputed) 4 Febrile seizure (within the age range of 3 months to 6 years) http://purl.obolibrary.org/obo/HP_0002373 GCST002673 Genome-wide genotyping array 5188 2015-06-26 25344690 Feenstra B 2014-10-26 Nat Genet www.ncbi.nlm.nih.gov/pubmed/25344690 Common variants associated with general and MMR vaccine-related febrile seizures. Febrile seizures (MMR vaccine-related) 929 European ancestry cases, 4,118 European ancestry controls Up to 408 European ancestry cases, Up to 1,645 European ancestry controls Illumina [8129524] (imputed) 10 MMR-related febrile seizures http://www.ebi.ac.uk/efo/EFO_0006519 GCST002674 Genome-wide genotyping array 5047 2014-11-27 24861553 Wen W 2014-05-26 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/24861553 Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index. Body mass index 82,438 East Asian ancestry individuals, 4,301 South East Asian ancestry individuals Up to 47,352 East Asian ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 25 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST002461 Genome-wide genotyping array 86739 2014-03-22 24014518 Kasperaviciute D 2013-09-06 Brain www.ncbi.nlm.nih.gov/pubmed/24014518 Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A. Mesial temporal lobe epilepsy with hippocampal sclerosis up to 1,018 European ancestry cases, 7,552 European ancestry controls 959 European ancestry cases, 3,591 European ancestry controls Illumina [531164] 2 Mesial temporal lobe epilepsy with hippocampal sclerosis http://www.orpha.net/ORDO/Orphanet_99701 GCST002170 Genome-wide genotyping array 8570 2015-01-14 24941225 Liang Y 2014-06-18 PLoS One www.ncbi.nlm.nih.gov/pubmed/24941225 Genetic variations affecting serum carcinoembryonic antigen levels and status of regional lymph nodes in patients with sporadic colorectal cancer from Southern China. Elevated serum carcinoembryonic antigen levels 1,999 Chinese ancestry individuals NA Illumina [709211] (imputed) 13 serum carcinoembryonic antigen measurement http://www.ebi.ac.uk/efo/EFO_0005760 GCST002485 Genome-wide genotyping array 1999 2014-03-13 23966204 Ledda M 2013-08-20 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23966204 GWAS of human bitter taste perception identifies new loci and reveals additional complexity of bitter taste genetics. Bitter taste perception 503 Brazilian ancestry individuals 104 Brazilian ancestry individuals Illumina [~ 1000000] 3 sensory perception of bitter taste http://purl.obolibrary.org/obo/GO_0050913 GCST002144 Genome-wide genotyping array 503 2014-11-02 24658283 Zhang R 2014-03-22 Carcinogenesis www.ncbi.nlm.nih.gov/pubmed/24658283 A genome-wide gene-environment interaction analysis for tobacco smoke and lung cancer susceptibility. Lung cancer (smoking interaction) 1,506 Han Chinese ancestry smoker cases, 825 Han Chinese ancestry non-smoker cases, 1,309 Han Chinese ancestry smoker controls, 1,768 Han Chinese ancestry non-smoker controls 912 Han Chinese ancestry smoker cases, 622 Han Chinese ancestry non-smoker cases, 572 Han Chinese ancestry smoker controls, 917 Han Chinese ancestry non-smoker controls Affymetrix [591370] 2 smoking status measurement, lung carcinoma http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0001071 GCST002392 Genome-wide genotyping array 5408 2012-11-15 22961080 Li H 2012-09-06 Diabetes www.ncbi.nlm.nih.gov/pubmed/22961080 A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans. Type 2 diabetes 1,839 Han Chinese ancestry cases, 1,873 Han Chinese ancestry controls 15,979 East Asian ancestry cases, 19,360 East Asian ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 159 Filipino ancestry cases, 1,624 Filipino ancestry controls Illumina [2234194] (imputed) 10 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST001666 Genome-wide genotyping array 3712 2014-11-21 24850809 Verweij N 2014-05-21 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/24850809 Genetic determinants of P wave duration and PR segment. P wave duration 16,468 European ancestry individuals NA Illumina [2300000] (imputed) 3 P wave duration http://www.ebi.ac.uk/efo/EFO_0005094 GCST002457 Genome-wide genotyping array 16468 2014-11-21 24850809 Verweij N 2014-05-21 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/24850809 Genetic determinants of P wave duration and PR segment. PR segment duration 16,468 European ancestry individuals NA Illumina [2300000] (imputed) 8 PR segment http://www.ebi.ac.uk/efo/EFO_0005095 GCST002456 Genome-wide genotyping array 16468 2014-11-08 24709693 Cobb J 2014-04-08 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/24709693 Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases. Response to methotrexate in juvenile idiopathic arthritis 694 European ancestry child cases NA Illumina [586062] 18 response to methotrexate http://purl.obolibrary.org/obo/GO_0031427 GCST002408 Genome-wide genotyping array 694 2013-02-28 23207651 Davies G 2012-12-04 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/23207651 A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing. Cognitive decline 3,280 European ancestry individuals 1,367 European ancestry individuals Illumina [549692] 1 Mental deterioration http://purl.obolibrary.org/obo/HP_0001268 GCST001761 Genome-wide genotyping array 3280 2015-06-25 23247143 Yu B 2012-12-16 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/23247143 Association of genome-wide variation with highly sensitive cardiac troponin-T levels in European Americans and Blacks: a meta-analysis from atherosclerosis risk in communities and cardiovascular health studies. Cardiac Troponin-T levels 9,491 European ancestry individuals, up to 2,053 African American individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 18 cardiac troponin T measurement http://www.ebi.ac.uk/efo/EFO_0005043 GCST001776 Genome-wide genotyping array 11544 2014-07-02 21156761 Padyukov L 2010-12-14 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/21156761 A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis. Rheumatoid arthritis 1,147 European ancestry ACPA positive RA cases, 774 European ancestry ACPA negative RA cases, 1,079 European ancestry controls 887 European ancestry ACPA positive RA cases, 1,218 European ancestry controls Illumina [1723056] (imputed) 16 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST000917 Genome-wide genotyping array 3000 2014-03-14 23992748 Drake KA 2013-08-29 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/23992748 A genome-wide association study of bronchodilator response in Latinos implicates rare variants. Asthma (bronchodilator response) up to 1,782 Latino child cases 529 Latino child cases Affymetrix [568037] 0 response to bronchodilator http://purl.obolibrary.org/obo/GO_0097366 GCST002154 Genome-wide genotyping array 1782 2012-11-21 22916037 Inouye M 2012-08-16 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22916037 Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis. Metabolite levels 6,608 European ancestry individuals NA Illumina [~ 2000000] (imputed) 34 coronary artery calcification http://www.ebi.ac.uk/efo/EFO_0004723 GCST001639 Genome-wide genotyping array 6608 2014-11-09 24740154 Lange EM 2014-04-16 PLoS One www.ncbi.nlm.nih.gov/pubmed/24740154 Genome-wide association scan for variants associated with early-onset prostate cancer. Prostate cancer (early onset) 931 European ancestry cases, 4,120 European ancestry controls 2,571 European ancestry cases, 921 European ancestry controls Illumina [2639562] (imputed) 9 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST002413 Genome-wide genotyping array 5051 2015-04-01 25130324 Cai DC 2014-08-29 Genes Brain Behav www.ncbi.nlm.nih.gov/pubmed/25130324 A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus. Heschl's gyrus morphology 1,778 European ancestry individuals, 1,276 individuals NA Affymetrix, Illumina [4103035] (imputed) 33 Heschl's gyrus morphology measurement http://www.ebi.ac.uk/efo/EFO_0005852 GCST002579 Genome-wide genotyping array 3054 2015-07-07 25288136 Cornelis MC 2014-10-07 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/25288136 Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Coffee consumption (cups per day) 91,462 European ancestry individuals 30,062 European ancestry individuals, 7,964 African American individuals Affymetrix, Illumina [2373958] (imputed) 9 coffee consumption, cups of coffee per day measurement http://www.ebi.ac.uk/efo/EFO_0004330, http://www.ebi.ac.uk/efo/EFO_0006782 GCST002650 Genome-wide genotyping array 91462 2015-07-07 25288136 Cornelis MC 2014-10-07 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/25288136 Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Coffee consumption 17,479 European ancestry high consumption individuals, 31,049 European ancestry no or low consumption individuals 6,497 European ancestry high consumption individuals, 432 African American high consumption individuals, 6,972 European ancestry no or low consumption individuals, 3,413 African American no or low consumption individuals Affymetrix, Illumina [2376205] (imputed) 4 coffee consumption http://www.ebi.ac.uk/efo/EFO_0004330 GCST002651 Genome-wide genotyping array 48528 2011-02-25 21242260 Cui R 2011-01-17 Gut www.ncbi.nlm.nih.gov/pubmed/21242260 Common variant in 6q26-q27 is associated with distal colon cancer in an Asian population. Colorectal cancer 1,583 Japanese ancestry cases, 1,898 Japanese ancestry controls 4,584 Japanese ancestry cases, 225 Korean ancestry distal cases, 2,973 East Asian ancestry controls Illumina [391749] 2 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST000948 Genome-wide genotyping array 3481 2015-05-18 25279986 Skibola CF 2014-10-02 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/25279986 Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region. Follicular lymphoma 2,728 European ancestry cases, 7,758 European ancestry controls 1,795 European ancestry cases, 5,586 European ancestry controls Illumina [up to 21554489] 9 neoplasm of mature B-cells http://www.ebi.ac.uk/efo/EFO_0000096 GCST002643 Genome-wide genotyping array 10486 2014-12-17 24951543 Liao J 2014-06-20 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/24951543 Meta-analysis of genome-wide association studies in multiethnic Asians identifies two loci for age-related nuclear cataract. Age-related nuclear cataracts 2,369 Malay ancestry individuals, 2,200 Indian ancestry individuals, 2,571 Chinese ancestry individuals NA Illumina [4736131] (imputed) 15 Age-related nuclear cataract http://purl.obolibrary.org/obo/HP_0011142 GCST002498 Genome-wide genotyping array 7140 2015-12-18 25760438 Anderson D 2015-03-11 PLoS One www.ncbi.nlm.nih.gov/pubmed/25760438 First genome-wide association study in an Australian aboriginal population provides insights into genetic risk factors for body mass index and type 2 diabetes. Body mass index 361 Martu Australian Aboriginal ancestry individuals NA Illumina [1075436] (imputed) 11 longitudinal BMI measurement http://www.ebi.ac.uk/efo/EFO_0005937 GCST002805 Genome-wide genotyping array 361 2015-12-18 25760438 Anderson D 2015-03-11 PLoS One www.ncbi.nlm.nih.gov/pubmed/25760438 First genome-wide association study in an Australian aboriginal population provides insights into genetic risk factors for body mass index and type 2 diabetes. Type 2 diabetes 89 Martu Australian Aboriginal ancestry cases, 302 Martu Australian Aboriginal ancestry controls NA Illumina [1075436] (imputed) 17 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST002806 Genome-wide genotyping array 391 2015-06-22 25729143 Ahmetov I 2014-10-21 Biol Sport www.ncbi.nlm.nih.gov/pubmed/25729143 Genome-wide association study identifies three novel genetic markers associated with elite endurance performance. Maximal oxygen uptake response 15 Russian ancestry male long endurance athletes, 17 Russian ancestry female long endurance athletes, 31 Russian ancestry middle and short endurance athletes, 17 Russian ancestry middle and short endurance athletes NA Illumina [1140419] 4 maximal oxygen uptake measurement http://www.ebi.ac.uk/efo/EFO_0004887 GCST002664 Genome-wide genotyping array 80 2016-02-04 25778476 Jun G 2015-03-17 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/25778476 A novel Alzheimer disease locus located near the gene encoding tau protein. Alzheimer's disease (APOE e4 interaction) 10,352 APOE e4+ cases, 9,207 APOE e4+ controls, 7,184 APOE e4- cases, 26,968 APOE e4- controls 1,250 APOE e4+ European ancestry cases, 536 APOE e4+ European ancestry controls, 718 APOE e4- European ancestry cases, 1,699 APOE e4- European ancestry controls NR [NR] 4 Alzheimer's disease, APOE carrier status http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0007659 GCST002814 Genome-wide genotyping array 53727 2016-02-03 25778476 Jun G 2015-03-17 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/25778476 A novel Alzheimer disease locus located near the gene encoding tau protein. Alzheimer's disease in APOE e4+ carriers 10,352 cases, 9,207 controls 1,250 European ancestry cases, 536 European ancestry controls NR [NR] 17 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST002813 Genome-wide genotyping array 19559 2016-02-03 25778476 Jun G 2015-03-17 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/25778476 A novel Alzheimer disease locus located near the gene encoding tau protein. Alzheimer's disease in APOE e4- carriers 7,184 cases, 26,968 controls 718 European ancestry cases, 1,699 European ancestry controls NR [NR] 29 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST002817 Genome-wide genotyping array 34152 2015-11-14 25784220 Sharma S 2015-03-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/25784220 A PAX1 enhancer locus is associated with susceptibility to idiopathic scoliosis in females. Adolescent idiopathic scoliosis 371 European ancestry female cases, 76 European ancestry male cases, 533 European ancestry female controls, 204 European ancestry male controls 715 European, Black, Hispanic and other ancestry trios, 216 European ancestry cases, 336 European ancestry controls, 1,050 Japanese ancestry female cases, 1,474 Japanese ancestry female controls Illumina [727670] 1 adolescent idiopathic scoliosis http://www.ebi.ac.uk/efo/EFO_0005423 GCST002819 Genome-wide genotyping array 1184 2015-12-03 25802187 Jiang DK 2015-04-28 Hepatology www.ncbi.nlm.nih.gov/pubmed/25802187 Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. Chronic hepatitis B infection 2,514 Chinese ancestry cases, 1,130 Chinese ancestry controls 6,600 Chinese ancestry cases, 8,127 Chinese ancestry controls Illumina [3680900] (imputed) 12 chronic hepatitis B virus infection http://www.ebi.ac.uk/efo/EFO_0004239 GCST002879 Genome-wide genotyping array 3644 2016-01-27 25786224 Johnson EO 2015-03-18 PLoS One www.ncbi.nlm.nih.gov/pubmed/25786224 Novel genetic locus implicated for HIV-1 acquisition with putative regulatory links to HIV replication and infectivity: a genome-wide association study. HIV-1 susceptibility 628 African American high risk-cases, 1,376 African American high-risk controls, 327 European ancestry high-risk cases, 805 European ancestry high-risk controls 1,395 African American high-risk cases, 457 African American high-risk controls, 513 European ancestry high-risk cases, 168 European ancestry high-risk controls Illumina [~ 8000000] (imputed) 7 HIV-1 infection, Susceptibility to viral and mycobacterial infections http://www.ebi.ac.uk/efo/EFO_0000180, http://www.orpha.net/ORDO/Orphanet_391311 GCST002818 Genome-wide genotyping array 3136 2017-05-23 28100913 Ueta M 2017-01-19 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/28100913 Genome-wide association study using the ethnicity-specific Japonica array: identification of new susceptibility loci for cold medicine-related Stevens-Johnson syndrome with severe ocular complications. Cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) with severe ocular complications 117 Japanese ancestry cases, 688 Japanese ancestry controls 52 East Asian ancestry cases, 302 East Asian ancestry controls Affymetrix [6714496] (imputed) 3 Stevens-Johnson syndrome, toxic epidermal necrolysis, response to cold medicine http://www.ebi.ac.uk/efo/EFO_0004276, http://www.ebi.ac.uk/efo/EFO_0004775, http://www.ebi.ac.uk/efo/EFO_0006997 GCST004072 Genome-wide genotyping array 805 2017-03-10 27094239 Joshi AD 2016-04-16 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/27094239 Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies. Gallstone disease 8,720 European ancestry cases, 55,152 European ancestry controls 6,489 European ancestry cases, 62,797 European ancestry controls, 1,499 African American cases, 9,145 African American controls, 1,056 Hispanic cases, 2,403 Hispanic controls Affymetrix, Illumina [at least 2305318] (imputed) 6 gallstones http://www.ebi.ac.uk/efo/EFO_0004210 GCST003725 Genome-wide genotyping array 63872 2017-06-02 28256260 Siitonen A 2017-02-02 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/28256260 Genetics of early-onset Parkinson's disease in Finland: exome sequencing and genome-wide association study. Early-onset Parkinson's disease 403 Finnish ancestry cases, 1,650 Finnish ancestry controls NA NR [12954715] (imputed) 13 Young adult-onset Parkinsonism http://www.orpha.net/ORDO/Orphanet_2828 GCST004138 Genome-wide genotyping array 2053 2017-07-13 28346443 Melin BS 2017-03-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28346443 Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors. Glioma 12,469 European ancestry cases, 18,190 European ancestry controls. NA Illumina [at least 6887412] (imputed) 18 central nervous system cancer, glioma http://www.ebi.ac.uk/efo/EFO_0000326, http://www.ebi.ac.uk/efo/EFO_0005543 GCST004347 Genome-wide genotyping array 30659 2017-07-13 28346443 Melin BS 2017-03-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28346443 Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors. Non-glioblastoma glioma 5,819 European ancestry cases, 18,190 European ancestry controls. NA Illumina [at least 6769856] (imputed) 19 central nervous system cancer, glioma http://www.ebi.ac.uk/efo/EFO_0000326, http://www.ebi.ac.uk/efo/EFO_0005543 GCST004348 Genome-wide genotyping array 24009 2017-07-13 28346443 Melin BS 2017-03-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28346443 Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors. Glioblastoma 6,191 European ancestry cases, 18,190 European ancestry controls. NA Illumina [at least 6790270] (imputed) 13 central nervous system cancer, glioblastoma multiforme http://www.ebi.ac.uk/efo/EFO_0000326, http://www.ebi.ac.uk/efo/EFO_0000519 GCST004349 Genome-wide genotyping array 24381 2018-05-18 29471430 Tanikawa C 2018-02-17 Carcinogenesis www.ncbi.nlm.nih.gov/pubmed/29471430 GWAS Identifies Two Novel Colorectal Cancer Loci at 16q24.1 and 20q13.12. Colorectal cancer 6,692 Japanese ancestry cases, 27,178 Japanese ancestry controls 3,713 Japanese ancestry cases, 7,333 Japanese ancestry controls Illumina [6774630] (imputed) 30 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST005591 Genome-wide genotyping array 33870 2018-03-16 29478698 Cheng Z 2018-01-11 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/29478698 Genome-wide Association Study Identifies a Regulatory Variant of RGMA Associated With Opioid Dependence in European Americans. Opioid dependence 3,058 European ancestry individuals 2,014 African American individuals Illumina [at least 4700000] (imputed) 11 opioid dependence http://www.ebi.ac.uk/efo/EFO_0005611 GCST005368 Genome-wide genotyping array 3058 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. beta-nerve growth factor levels 3,531 Finnish ancestry individuals NA NR [10700000] (imputed) 26 beta-nerve growth factor measurement http://www.ebi.ac.uk/efo/EFO_0008035 GCST004421 Genome-wide genotyping array 3531 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Vascular endothelial growth factor levels 7,118 Finnish ancestry individuals NA NR [10700000] (imputed) 40 vascular endothelial growth factor measurement http://www.ebi.ac.uk/efo/EFO_0004762 GCST004422 Genome-wide genotyping array 7118 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. CTACK levels 3,631 Finnish ancestry individuals NA NR [10700000] (imputed) 46 chemokine (C-C motif) ligand 27 measurement http://www.ebi.ac.uk/efo/EFO_0008082 GCST004420 Genome-wide genotyping array 3631 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Eotaxin levels 8,153 Finnish ancestry individuals NA NR [10700000] (imputed) 46 eotaxin measurement http://www.ebi.ac.uk/efo/EFO_0008122 GCST004460 Genome-wide genotyping array 8153 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Fibroblast growth factor basic levels 7,565 Finnish ancestry individuals NA NR [10700000] (imputed) 28 fibroblast growth factor basic measurement http://www.ebi.ac.uk/efo/EFO_0008130 GCST004459 Genome-wide genotyping array 7565 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Granulocyte-colony stimulating factor levels 7,904 Finnish ancestry individuals NA NR [10700000] (imputed) 20 granulocyte colony-stimulating factor measurement http://www.ebi.ac.uk/efo/EFO_0008142 GCST004458 Genome-wide genotyping array 7904 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Growth-regulated protein alpha levels 3,505 Finnish ancestry individuals NA NR [10700000] (imputed) 26 growth-regulated alpha protein measurement http://www.ebi.ac.uk/efo/EFO_0008146 GCST004457 Genome-wide genotyping array 3505 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Hepatocyte growth factor levels 8,292 Finnish ancestry individuals NA NR [10700000] (imputed) 25 hepatocyte growth factor measurement http://www.ebi.ac.uk/efo/EFO_0006903 GCST004449 Genome-wide genotyping array 8292 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Interferon gamma levels 7,701 Finnish ancestry individuals NA NR [10700000] (imputed) 29 interferon gamma measurement http://www.ebi.ac.uk/efo/EFO_0008165 GCST004456 Genome-wide genotyping array 7701 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Interleukin-1-beta levels 3,309 Finnish ancestry individuals NA NR [10700000] (imputed) 23 interleukin-1 beta measurement http://www.ebi.ac.uk/efo/EFO_0004812 GCST004448 Genome-wide genotyping array 3309 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Interleukin-1-receptor antagonist levels 3,638 Finnish ancestry individuals NA NR [10700000] (imputed) 22 interleukin 1 receptor antagonist measurement http://www.ebi.ac.uk/efo/EFO_0004754 GCST004447 Genome-wide genotyping array 3638 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Interleukin-2 levels 3,475 Finnish ancestry individuals NA NR [10700000] (imputed) 26 interleukin 2 measurement http://www.ebi.ac.uk/efo/EFO_0008331 GCST004455 Genome-wide genotyping array 3475 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Interleukin-2 receptor antagonist levels 3,677 Finnish ancestry individuals NA NR [10700000] (imputed) 27 interleukin 2 receptor antagonist measurement http://www.ebi.ac.uk/efo/EFO_0008332 GCST004454 Genome-wide genotyping array 3677 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Interleukin-4 levels 8,124 Finnish ancestry individuals NA NR [10700000] (imputed) 24 interleukin 4 measurement http://www.ebi.ac.uk/efo/EFO_0008184 GCST004453 Genome-wide genotyping array 8124 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Interleukin-5 levels 3,364 Finnish ancestry individuals NA NR [10700000] (imputed) 17 interleukin 5 measurement http://www.ebi.ac.uk/efo/EFO_0008185 GCST004452 Genome-wide genotyping array 3364 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Interleukin-6 levels 8,189 Finnish ancestry individuals NA NR [10700000] (imputed) 29 interleukin-6 measurement http://www.ebi.ac.uk/efo/EFO_0004810 GCST004446 Genome-wide genotyping array 8189 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Interleukin-7 levels 3,409 Finnish ancestry individuals NA NR [10700000] (imputed) 23 interleukin 7 measurement http://www.ebi.ac.uk/efo/EFO_0008189 GCST004451 Genome-wide genotyping array 3409 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Interleukin-8 levels 3,526 Finnish ancestry individuals NA NR [10700000] (imputed) 18 interleukin-8 measurement http://www.ebi.ac.uk/efo/EFO_0004811 GCST004445 Genome-wide genotyping array 3526 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Interleukin-9 levels 3,634 Finnish ancestry individuals NA NR [10700000] (imputed) 25 interleukin 9 measurement http://www.ebi.ac.uk/efo/EFO_0008192 GCST004450 Genome-wide genotyping array 3634 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Interleukin-10 levels 7,681 Finnish ancestry individuals NA NR [10700000] (imputed) 34 interleukin 10 measurement http://www.ebi.ac.uk/efo/EFO_0004750 GCST004444 Genome-wide genotyping array 7681 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Interleukin-13 levels 3,557 Finnish ancestry individuals NA NR [10700000] (imputed) 33 interleukin 13 measurement http://www.ebi.ac.uk/efo/EFO_0008171 GCST004443 Genome-wide genotyping array 3557 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Interleukin-17 levels 7,760 Finnish ancestry individuals NA NR [10700000] (imputed) 34 interleukin 17 measurement http://www.ebi.ac.uk/efo/EFO_0008174 GCST004442 Genome-wide genotyping array 7760 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Interleukin-18 levels 3,636 Finnish ancestry individuals NA NR [10700000] (imputed) 44 interleukin 18 measurement http://www.ebi.ac.uk/efo/EFO_0004581 GCST004441 Genome-wide genotyping array 3636 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Macrophage Migration Inhibitory Factor levels 3,494 Finnish ancestry individuals NA NR [10700000] (imputed) 26 macrophage migration inhibitory factor measurement http://www.ebi.ac.uk/efo/EFO_0008221 GCST004423 Genome-wide genotyping array 3494 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Interferon gamma-induced protein 10 levels 3,685 Finnish ancestry individuals NA NR [10700000] (imputed) 36 C-X-C motif chemokine 10 measurement http://www.ebi.ac.uk/efo/EFO_0008056 GCST004440 Genome-wide genotyping array 3685 2017-05-11 28072414 Charney AW 2017-01-10 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/28072414 Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder. Bipolar disorder 13,903 European ancestry cases, 19,279 European ancestry controls. NA Affymetrix, Illumina [8837380] (imputed) 8 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST003962 Genome-wide genotyping array 33182 2018-05-18 29495422 Xu H 2018-02-26 J Pers Med www.ncbi.nlm.nih.gov/pubmed/29495422 A Genome-Wide Association Study of Idiopathic Dilated Cardiomyopathy in African Americans. Idiopathic dilated cardiomyopathy 662 African American cases, 1,138 African American controls NA Affymetrix [up to 27494467] (imputed) 42 idiopathic dilated cardiomyopathy http://www.ebi.ac.uk/efo/EFO_0009094 GCST005588 Genome-wide genotyping array 1800 2017-04-21 28025368 Janicki PK 2016-06-10 Pain Med www.ncbi.nlm.nih.gov/pubmed/28025368 Analysis of Common Single Nucleotide Polymorphisms in Complex Regional Pain Syndrome: Genome Wide Association Study Approach and Pooled DNA Strategy. Complex regional pain syndrome 115 cases, 115 controls 115 cases, 115 controls Illumina [200251] 0 complex regional pain syndrome http://www.ebi.ac.uk/efo/EFO_1001998 GCST003930 Genome-wide genotyping array 230 2017-05-15 28011710 Benyamin B 2016-12-22 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28011710 Identification of novel loci affecting circulating chromogranins and related peptides. Circulating chromogranin peptide levels up to 540 European American and Mexican American individuals, up to 1,267 individuals NA Illumina [at least 2587527] (imputed) 5 CHGB cleavage product measurement, CHGA cleavage product measurement http://www.ebi.ac.uk/efo/EFO_0007910, http://www.ebi.ac.uk/efo/EFO_0007909 GCST004038 Genome-wide genotyping array 1807 2017-08-21 28334935 Raffield LM 2017-05-15 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28334935 Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation? Iron status biomarkers (ferritin levels) 12,375 Hispanic/Latino individuals NA Illumina [27700000] (imputed) 11 ferritin measurement http://www.ebi.ac.uk/efo/EFO_0004459 GCST004573 Genome-wide genotyping array 12375 2017-08-21 28334935 Raffield LM 2017-05-15 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28334935 Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation? Iron status biomarkers (iron levels) 12,580 Hispanic/Latino individuals NA Illumina [27700000] (imputed) 19 serum iron measurement http://www.ebi.ac.uk/efo/EFO_0006332 GCST004570 Genome-wide genotyping array 12580 2017-08-21 28334935 Raffield LM 2017-05-15 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28334935 Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation? Iron status biomarkers (total iron binding capacity) 12,586 Hispanic/Latino individuals NA Illumina [27700000] (imputed) 34 total iron binding capacity http://www.ebi.ac.uk/efo/EFO_0006334 GCST004571 Genome-wide genotyping array 12586 2017-08-21 28334935 Raffield LM 2017-05-15 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28334935 Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation? Iron status biomarkers (transferrin saturation) 12,589 Hispanic/Latino individuals NA Illumina [27700000] (imputed) 32 transferrin saturation measurement http://www.ebi.ac.uk/efo/EFO_0006333 GCST004572 Genome-wide genotyping array 12589 2017-06-01 28056976 Paziewska A 2017-01-06 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/28056976 A novel approach to genome-wide association analysis identifies genetic associations with primary biliary cholangitis and primary sclerosing cholangitis in Polish patients. Primary biliary cholangitis 443 Polish ancestry cases, 934 Polish ancestry controls NA Illumina [NR] 0 primary biliary cirrhosis http://www.ebi.ac.uk/efo/EFO_1001486 GCST004120 Genome-wide genotyping array 1377 2017-06-01 28056976 Paziewska A 2017-01-06 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/28056976 A novel approach to genome-wide association analysis identifies genetic associations with primary biliary cholangitis and primary sclerosing cholangitis in Polish patients. Primary sclerosing cholangitis 120 Polish ancestry cases, 934 Polish ancestry controls NA Illumina [NR] 0 sclerosing cholangitis http://www.ebi.ac.uk/efo/EFO_0004268 GCST004119 Genome-wide genotyping array 1054 2017-08-16 28521775 Manichaikul A 2017-05-18 Respir Res www.ncbi.nlm.nih.gov/pubmed/28521775 Genome-wide association study of subclinical interstitial lung disease in MESA. Subclinical trait of interstitial lung disease (basilar percentage of high attenuation areas on CT scan) 2,434 European ancestry individuals, 2,470 African American individuals, 2,065 Hispanic individuals, 702 Chinese ancestry individuals 3,013 European ancestry individuals Affymetrix [at least 897981] (imputed) 4 airway imaging measurement http://www.ebi.ac.uk/efo/EFO_0007627 GCST004526 Genome-wide genotyping array 7671 2017-08-16 28521775 Manichaikul A 2017-05-18 Respir Res www.ncbi.nlm.nih.gov/pubmed/28521775 Genome-wide association study of subclinical interstitial lung disease in MESA. Subclinical trait of interstitial lung disease (basilar peel-core ratio of high attentuation areas on CT scan) 2,434 European ancestry individuals, 2,470 African American individuals, 2,065 Hispanic individuals, 702 Chinese ancestry individuals NA Affymetrix [at least 897981] (imputed) 9 airway imaging measurement http://www.ebi.ac.uk/efo/EFO_0007627 GCST004525 Genome-wide genotyping array 7671 2017-08-16 28521775 Manichaikul A 2017-05-18 Respir Res www.ncbi.nlm.nih.gov/pubmed/28521775 Genome-wide association study of subclinical interstitial lung disease in MESA. Subclinical trait of interstitial lung disease (percentage of high attenuation areas on CT scan) 2,434 European ancestry individuals, 2,470 African American individuals, 2,065 Hispanic individuals, 702 Chinese ancestry individuals 3,013 European ancestry individuals Affymetrix [at least 897981] (imputed) 1 airway imaging measurement http://www.ebi.ac.uk/efo/EFO_0007627 GCST004527 Genome-wide genotyping array 7671 2018-08-08 24532676 Kim K 2014-02-14 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/24532676 High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci. Rheumatoid arthritis (ACPA-positive) 2,234 Korean ancestry cases, 7,065 Korean ancestry controls, 10,288 European ancestry cases, 35,502 European ancestry controls NA Illumina [133816] (imputed) 52 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST006048 Genome-wide genotyping array, Targeted genotyping array [ImmunoChip] 55089 2018-03-23 29452408 Shiga Y 2018-02-14 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/29452408 Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma. Glaucoma (primary open-angle) 3,980 Japanese ancestry cases, 18,815 Japanese ancestry controls 4,406 East Asian ancestry cases, 18,161 East Asian ancestry controls, 5,008 European ancestry cases, 35,472 European ancestry controls, 769 African American cases, 663 African American controls, 1,572 Sub-Saharan African ancestry cases, 1,374 Sub-Saharan African ancestry controls. Illumina [6109376] (imputed) 4 open-angle glaucoma http://www.ebi.ac.uk/efo/EFO_0004190 GCST005388 Genome-wide genotyping array 22795 2018-07-04 29453348 Chen CJ 2018-02-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29453348 ABCG2 contributes to the development of gout and hyperuricemia in a genome-wide association study. Gout 747 East Asian ancestry cases, 2,071 East Asian ancestry controls NA Affymetrix [537478] 2 gout http://www.ebi.ac.uk/efo/EFO_0004274 GCST005799 Genome-wide genotyping array 2818 2018-07-04 29453348 Chen CJ 2018-02-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29453348 ABCG2 contributes to the development of gout and hyperuricemia in a genome-wide association study. Gout vs. Hyperuricemia 747 East Asian ancestry gout cases, 747 East Asian ancestry hyperuricemia cases NA Affymetrix [537478] 1 gout, hyperuricemia http://www.ebi.ac.uk/efo/EFO_0004274, http://www.ebi.ac.uk/efo/EFO_0009104 GCST005801 Genome-wide genotyping array 1494 2018-07-04 29453348 Chen CJ 2018-02-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29453348 ABCG2 contributes to the development of gout and hyperuricemia in a genome-wide association study. Hyperuricemia 747 East Asian ancestry cases, 2,071 East Asian ancestry controls NA Affymetrix [537478] 1 hyperuricemia http://www.ebi.ac.uk/efo/EFO_0009104 GCST005802 Genome-wide genotyping array 2818 2018-06-22 29489655 Liu X 2018-03-01 Medicine (Baltimore) www.ncbi.nlm.nih.gov/pubmed/29489655 Genome-wide association study of maternal genetic effects and parent-of-origin effects on food allergy. Food allergy (parent-of-origin effect) 482 European ancestry trios, 19 European ancestry father-child pairs, 59 European ancestry mother-child pairs, 28 European ancestry affected children NA Illumina [NR] 6 food allergy measurement, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0007016, http://www.ebi.ac.uk/efo/EFO_0005939 GCST005721 Genome-wide genotyping array 588 2018-06-22 29489655 Liu X 2018-03-01 Medicine (Baltimore) www.ncbi.nlm.nih.gov/pubmed/29489655 Genome-wide association study of maternal genetic effects and parent-of-origin effects on food allergy. Peanut allergy (parent-of-origin effect) 247 European ancestry trios, 7 European ancestry father-child pairs, 33 European ancestry mother-child pairs, 14 European ancestry affected child NA Illumina [NR] 5 peanut allergy measurement, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0007017, http://www.ebi.ac.uk/efo/EFO_0005939 GCST005727 Genome-wide genotyping array 301 2018-06-22 29489655 Liu X 2018-03-01 Medicine (Baltimore) www.ncbi.nlm.nih.gov/pubmed/29489655 Genome-wide association study of maternal genetic effects and parent-of-origin effects on food allergy. Milk allergy (parent-of-origin effect) 230 European ancestry trios, 10 European ancestry father-child pairs, 25 European ancestry mother-child pairs, 10 European ancestry affected child NA Illumina [NR] 2 milk allergy measurement, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0007019, http://www.ebi.ac.uk/efo/EFO_0005939 GCST005726 Genome-wide genotyping array 275 2018-06-22 29489655 Liu X 2018-03-01 Medicine (Baltimore) www.ncbi.nlm.nih.gov/pubmed/29489655 Genome-wide association study of maternal genetic effects and parent-of-origin effects on food allergy. Egg allergy (parent-of-origin effect) 169 European ancestry trios, 5 European ancestry father-child pairs, 19 European ancestry mother-child pairs, 8 European ancestry affected child NA Illumina [NR] 3 egg allergy measurement, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0007018, http://www.ebi.ac.uk/efo/EFO_0005939 GCST005725 Genome-wide genotyping array 201 2018-06-22 29489655 Liu X 2018-03-01 Medicine (Baltimore) www.ncbi.nlm.nih.gov/pubmed/29489655 Genome-wide association study of maternal genetic effects and parent-of-origin effects on food allergy. Food allergy (maternal genetic effects) 588 European ancestry complete and incomplete trios NA Illumina [NR] 5 food allergy measurement, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0007016, http://www.ebi.ac.uk/efo/EFO_0005939 GCST005724 Genome-wide genotyping array 588 2018-06-22 29489655 Liu X 2018-03-01 Medicine (Baltimore) www.ncbi.nlm.nih.gov/pubmed/29489655 Genome-wide association study of maternal genetic effects and parent-of-origin effects on food allergy. Peanut allergy (maternal genetic effects) 301 European ancestry complete and incomplete trios NA Illumina [NR] 4 peanut allergy measurement, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0007017, http://www.ebi.ac.uk/efo/EFO_0005939 GCST005723 Genome-wide genotyping array 301 2018-06-22 29489655 Liu X 2018-03-01 Medicine (Baltimore) www.ncbi.nlm.nih.gov/pubmed/29489655 Genome-wide association study of maternal genetic effects and parent-of-origin effects on food allergy. Milk allergy (maternal genetic effects) 275 European ancestry complete and incomplete trios NA Illumina [NR] 2 milk allergy measurement, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0007019, http://www.ebi.ac.uk/efo/EFO_0005939 GCST005722 Genome-wide genotyping array 275 2018-06-22 29489655 Liu X 2018-03-01 Medicine (Baltimore) www.ncbi.nlm.nih.gov/pubmed/29489655 Genome-wide association study of maternal genetic effects and parent-of-origin effects on food allergy. Egg allergy (maternal genetic effects) 201 European ancestry complete and incomplete trios NA Illumina [NR] 5 egg allergy measurement, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0007018, http://www.ebi.ac.uk/efo/EFO_0005939 GCST005728 Genome-wide genotyping array 201 2018-05-04 25014791 Govind N 2014-08-14 Mol Med www.ncbi.nlm.nih.gov/pubmed/25014791 Immunochip identifies novel, and replicates known, genetic risk loci for rheumatoid arthritis in black South Africans. Rheumatoid arthritis 263 South African Black cases and 374 South African Black controls NA Illumina [103770] 3 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST005562 Targeted genotyping array [ImmunoChip] 637 2018-04-26 24387989 Mayes MD 2014-01-02 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/24387989 Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis. Diffuse cutaneous systemic sclerosis 574 European ancestry cases, 3,466 European ancestry controls 1,217 European ancestry cases, 5,935 European ancestry controls Illumina [126270] 1 diffuse scleroderma http://www.ebi.ac.uk/efo/EFO_0000404 GCST005535 Targeted genotyping array [ImmunoChip] 4040 2018-04-26 24387989 Mayes MD 2014-01-02 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/24387989 Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis. Systemic sclerosis 671 European ancestry ACA-positive cases, 347 European ancestry ATA-positive cases, 815 European ancestry cases, 3,466 European ancestry controls 1,387 European ancestry ACA-positive cases, 896 European ancestry ATA-positive cases, 1,734 European ancestry cases, 5,935 European ancestry controls Illumina [126270] 12 systemic scleroderma http://www.ebi.ac.uk/efo/EFO_0000717 GCST005534 Targeted genotyping array [ImmunoChip] 5299 2018-04-26 24387989 Mayes MD 2014-01-02 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/24387989 Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis. Limited cutaneous systemic scleroderma 1,127 European ancestry cases, 3,466 European ancestry controls 2,507 European ancestry cases, 5,935 European ancestry controls Illumina [126270] 4 limited scleroderma http://www.ebi.ac.uk/efo/EFO_1001017 GCST005533 Targeted genotyping array [ImmunoChip] 4593 2017-06-28 28373160 Klarin D 2017-04-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/28373160 Genetic Analysis of Venous Thromboembolism in UK Biobank Identifies the ZFPM2 Locus and Implicates Obesity as a Causal Risk Factor. Venous thromboembolism 3,290 European ancestry cases, 116,868 European ancestry controls 65,734 cases and controls (see Germain, 2015) Affymetrix [9155762] (imputed) 9 venous thromboembolism http://www.ebi.ac.uk/efo/EFO_0004286 GCST004256 Genome-wide genotyping array 120158 2018-12-19 26272072 Jiang X 2015-08-13 Rheumatology (Oxford) www.ncbi.nlm.nih.gov/pubmed/26272072 An Immunochip-based interaction study of contrasting interaction effects with smoking in ACPA-positive versus ACPA-negative rheumatoid arthritis. ACPA-negative rheumatoid arthritis (smoking interaction) 340 European ancestry never-smoker cases, 493 European ancestry ever-smoker cases, 746 European ancestry never-smoker controls, 994 European ancestry ever-smoker controls NA Illumina [133648] (imputed) 0 rheumatoid arthritis, smoking status measurement, ACPA-negative rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0009460 GCST006807 Targeted genotyping array [ImmunoChip] 2573 2018-10-17 26272072 Jiang X 2015-08-13 Rheumatology (Oxford) www.ncbi.nlm.nih.gov/pubmed/26272072 An Immunochip-based interaction study of contrasting interaction effects with smoking in ACPA-positive versus ACPA-negative rheumatoid arthritis. ACPA-positive rheumatoid arthritis (smoking interaction) 340 European ancestry never-smoker cases, 493 European ancestry ever-smoker cases, 746 European ancestry never-smoker controls, 994 European ancestry ever-smoker controls 187 European ancestry never-smoker cases, 421 European ancestry ever-smoker cases, 461 European ancestry never-smoker controls, 447 European ancestry ever-smoker controls Illumina [133648] (imputed) 15 rheumatoid arthritis, smoking status measurement, ACPA-positive rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0009459 GCST006410 Targeted genotyping array [ImmunoChip] 2573 2017-05-12 27992413 Ji SG 2016-12-19 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27992413 Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease. Primary sclerosing cholangitis 2,871 European ancestry cases, 12,019 European ancestry controls 1,925 European ancestry cases, 7,936 European ancestry controls Affymetrix, Illumina [7891602] (imputed) 30 sclerosing cholangitis http://www.ebi.ac.uk/efo/EFO_0004268 GCST004030 Genome-wide genotyping array 14890 2017-04-19 28000841 Baek SH 2016-12-14 Mol Med Rep www.ncbi.nlm.nih.gov/pubmed/28000841 Genome-wide association scans for idiopathic osteonecrosis of the femoral head in a Korean population. Idiopathic osteonecrosis of the femoral head 217 Korean ancestry cases, 217 Korean ancestry controls NA Affymetrix [509886] 8 idiopathic osteonecrosis of the femoral head http://www.ebi.ac.uk/efo/EFO_1001930 GCST003918 Genome-wide genotyping array 434 2017-03-28 27980656 Justice AE 2016-10-18 BMC Proc www.ncbi.nlm.nih.gov/pubmed/27980656 Genome-wide association of trajectories of systolic blood pressure change. Systolic blood pressure change trajectory up to 683 Mexican American individuals from 20 families NA Illumina [at least 472049] (imputed) 10 systolic blood pressure change measurement http://www.ebi.ac.uk/efo/EFO_0006944 GCST003825 Genome-wide genotyping array 703 2017-06-02 28067908 de Lange KM 2017-01-09 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28067908 Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. Crohn's disease 12,194 European and unknown ancestry cases, 28,072 European and unknown ancestry controls NA Illumina [9560910] (imputed) 119 Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000384 GCST004132 Genome-wide genotyping array 40266 2017-06-02 28067908 de Lange KM 2017-01-09 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28067908 Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. Ulcerative colitis 12,366 European and unknown ancestry cases, 33,609 European and unknown ancestry controls NA Illumina [9578670] (imputed) 80 ulcerative colitis http://www.ebi.ac.uk/efo/EFO_0000729 GCST004133 Genome-wide genotyping array 45975 2017-06-02 28067908 de Lange KM 2017-01-09 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28067908 Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. Inflammatory bowel disease 25,042 European and unknown ancestry cases, 34,915 European and unknown ancestry controls NA Illumina [9725440] (imputed) 135 inflammatory bowel disease http://www.ebi.ac.uk/efo/EFO_0003767 GCST004131 Genome-wide genotyping array 59957 2017-03-20 27629089 Sailer A 2016-09-14 Neurology www.ncbi.nlm.nih.gov/pubmed/27629089 A genome-wide association study in multiple system atrophy. Multiple system atrophy (pathologically confirmed) 295 European ancestry cases, 3,864 European ancestry controls NA Illumina [4903804] (imputed) 16 multiple system atrophy http://www.ebi.ac.uk/efo/EFO_1001050 GCST003783 Genome-wide genotyping array 4159 2017-03-20 27629089 Sailer A 2016-09-14 Neurology www.ncbi.nlm.nih.gov/pubmed/27629089 A genome-wide association study in multiple system atrophy. Multiple system atrophy 918 European ancestry cases, 3,864 European ancestry controls NA Illumina [4903804] (imputed) 22 multiple system atrophy http://www.ebi.ac.uk/efo/EFO_1001050 GCST003784 Genome-wide genotyping array 4782 2018-07-04 29453196 Sato Y 2018-02-16 J Med Genet www.ncbi.nlm.nih.gov/pubmed/29453196 Genome-wide association study identifies ERBB4 on 2q34 as a novel locus associated with sperm motility in Japanese men. Sperm motility 811 Japanese ancestry males 779 Japanese ancestry males Illumina [3901256] (imputed) 1 sperm motility measurement http://www.ebi.ac.uk/efo/EFO_0008578 GCST005798 Genome-wide genotyping array 811 2018-07-11 29497042 Verweij N 2018-03-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29497042 Genetic study links components of the autonomous nervous system to heart-rate profile during exercise. Heart rate increase in response to exercise 5,4137 European ancestry individuals, 1,744 Asian ancestry individuals, 1,445 African ancestry individuals, 468 admixed individuals, 1,024 individuals NA Affymetrix [509255] (imputed) 11 heart rate response to exercise http://www.ebi.ac.uk/efo/EFO_0009184 GCST005845 Genome-wide genotyping array 58818 2018-07-11 29497042 Verweij N 2018-03-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29497042 Genetic study links components of the autonomous nervous system to heart-rate profile during exercise. Heart rate response to recovery post exercise (30 sec) 5,4137 European ancestry individuals, 1,744 Asian individuals, 1,445 African individuals, 468 admixed individuals, 1,024 individuals NA Affymetrix [509255] (imputed) 14 heart rate response to recovery post exercise http://www.ebi.ac.uk/efo/EFO_0009185 GCST005850 Genome-wide genotyping array 58818 2018-07-11 29497042 Verweij N 2018-03-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29497042 Genetic study links components of the autonomous nervous system to heart-rate profile during exercise. Heart rate response to recovery post exercise (40 sec) 5,4137 European ancestry individuals, 1,744 Asian individuals, 1,445 African individuals, 468 admixed individuals, 1,024 individuals NA Affymetrix [509255] (imputed) 14 heart rate response to recovery post exercise http://www.ebi.ac.uk/efo/EFO_0009185 GCST005849 Genome-wide genotyping array 58818 2018-07-11 29497042 Verweij N 2018-03-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29497042 Genetic study links components of the autonomous nervous system to heart-rate profile during exercise. Heart rate response to recovery post exercise (50 sec) 5,4137 European ancestry individuals, 1,744 Asian individuals, 1,445 African individuals, 468 admixed individuals, 1,024 individuals NA Affymetrix [509255] (imputed) 18 heart rate response to recovery post exercise http://www.ebi.ac.uk/efo/EFO_0009185 GCST005848 Genome-wide genotyping array 58818 2018-07-11 29497042 Verweij N 2018-03-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29497042 Genetic study links components of the autonomous nervous system to heart-rate profile during exercise. Heart rate response to recovery post exercise (10 sec) 5,4137 European ancestry individuals, 1,744 Asian individuals, 1,445 African individuals, 468 admixed individuals, 1,024 individuals NA Affymetrix [509255] (imputed) 15 heart rate response to recovery post exercise http://www.ebi.ac.uk/efo/EFO_0009185 GCST005846 Genome-wide genotyping array 58818 2018-07-11 29497042 Verweij N 2018-03-01 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29497042 Genetic study links components of the autonomous nervous system to heart-rate profile during exercise. Heart rate response to recovery post exercise (20 sec) 5,4137 European ancestry individuals, 1,744 Asian individuals, 1,445 African individuals, 468 admixed individuals, 1,024 individuals NA Affymetrix [509255] (imputed) 16 heart rate response to recovery post exercise http://www.ebi.ac.uk/efo/EFO_0009185 GCST005847 Genome-wide genotyping array 58818 2017-06-02 28081215 Pardo LM 2017-01-12 PLoS One www.ncbi.nlm.nih.gov/pubmed/28081215 Genome-Wide Association Studies of Multiple Keratinocyte Cancers. Multiple keratinocyte cancers 2,106 European ancestry multiple keratinocyte cancer cases, 2,061 European ancestry single keratinocyte cancer cases, 135 European and unknown ancestry multiple keratinocyte cancer cases, 761 European and unknown ancestry single keratinocyte cancer cases NA Affymetrix, Illumina [up to 9001799] (imputed) 17 squamous cell carcinoma, multiple keratinocyte carcinoma susceptibility measurement, basal cell carcinoma http://www.ebi.ac.uk/efo/EFO_0000707, http://www.ebi.ac.uk/efo/EFO_0007932, http://www.ebi.ac.uk/efo/EFO_0004193 GCST004134 Genome-wide genotyping array 5063 2017-05-12 28025584 da Silva Filho MI 2016-12-27 Leukemia www.ncbi.nlm.nih.gov/pubmed/28025584 Genome-wide association study of immunoglobulin light chain amyloidosis in three patient cohorts: comparison with myeloma. Immunoglobulin light chain (AL) amyloidosis 1,229 cases, 7,526 controls NA Affymetrix, Illumina [NR] (imputed) 10 AL amyloidosis http://www.orpha.net/ORDO/Orphanet_85443 GCST004028 Genome-wide genotyping array 8755 2017-04-10 27981573 Zhong WP 2016-12-16 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/27981573 Genomewide Association Study Identifies Novel Genetic Loci That Modify Antiplatelet Effects and Pharmacokinetics of Clopidogrel. Response to clopidogrel therapy in coronary heart disease 115 Han Chinese ancestry cases NA Illumina [703143] 0 platelet reactivity measurement, response to clopidogrel http://www.ebi.ac.uk/efo/EFO_0004985, http://purl.obolibrary.org/obo/GO_1903493 GCST003899 Genome-wide genotyping array 115 2017-07-19 28333195 Uimari O 2017-04-01 Hum Reprod www.ncbi.nlm.nih.gov/pubmed/28333195 Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis. Endometriosis 3,194 European ancestry cases, 7,060 European ancestry controls. NA Illumina [NR] (imputed) 6 endometriosis http://www.ebi.ac.uk/efo/EFO_0001065 GCST004368 Genome-wide genotyping array 10254 2017-07-19 28333195 Uimari O 2017-04-01 Hum Reprod www.ncbi.nlm.nih.gov/pubmed/28333195 Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis. Ovarian disease with few adhesions 1,686 European ancestry cases, 7,060 European ancestry controls. NA Illumina [NR] (imputed) 4 endometriosis http://www.ebi.ac.uk/efo/EFO_0001065 GCST004369 Genome-wide genotyping array 8746 2017-07-19 28333195 Uimari O 2017-04-01 Hum Reprod www.ncbi.nlm.nih.gov/pubmed/28333195 Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis. Deep ovarian and/or rectovaginal disease with dense adhesions 1,364 European ancestry cases, 7,060 European ancestry controls. NA Illumina [NR] (imputed) 10 endometriosis http://www.ebi.ac.uk/efo/EFO_0001065 GCST004370 Genome-wide genotyping array 8424 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Interleukin-12p70 levels 8,270 Finnish ancestry individuals NA NR [10700000] (imputed) 36 interleukin 12 measurement http://www.ebi.ac.uk/efo/EFO_0004753 GCST004439 Genome-wide genotyping array 8270 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Interleukin-16 levels 3,483 Finnish ancestry individuals NA NR [10700000] (imputed) 22 interleukin 16 measurement http://www.ebi.ac.uk/efo/EFO_0008173 GCST004430 Genome-wide genotyping array 3483 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Monocyte chemoattractant protein-1 levels 8,293 Finnish ancestry individuals NA NR [10700000] (imputed) 53 CCL2 measurement http://www.ebi.ac.uk/efo/EFO_0004749 GCST004438 Genome-wide genotyping array 8293 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Monocyte chemoattractant protein-3 levels 843 Finnish ancestry individuals NA NR [10700000] (imputed) 14 C-C motif chemokine 7 measurement http://www.ebi.ac.uk/efo/EFO_0008054 GCST004437 Genome-wide genotyping array 843 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Macrophage colony stimulating factor levels 840 Finnish ancestry individuals NA NR [10700000] (imputed) 23 macrophage colony stimulating factor measurement http://www.ebi.ac.uk/efo/EFO_0008217 GCST004436 Genome-wide genotyping array 840 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Monokine induced by gamma interferon levels 3,685 Finnish ancestry individuals NA NR [10700000] (imputed) 35 monokine induced by gamma interferon measurement http://www.ebi.ac.uk/efo/EFO_0008236 GCST004435 Genome-wide genotyping array 3685 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Macrophage inflammatory protein 1a levels 3,522 Finnish ancestry individuals NA NR [10700000] (imputed) 22 macrophage inflammatory protein 1a measurement http://www.ebi.ac.uk/efo/EFO_0008218 GCST004434 Genome-wide genotyping array 3522 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Macrophage inflammatory protein 1b levels 8,243 Finnish ancestry individuals NA NR [10700000] (imputed) 104 macrophage inflammatory protein 1b measurement http://www.ebi.ac.uk/efo/EFO_0008219 GCST004433 Genome-wide genotyping array 8243 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Platelet-derived growth factor BB levels 8,293 Finnish ancestry individuals NA NR [10700000] (imputed) 38 platelet-derived growth factor BB measurement http://www.ebi.ac.uk/efo/EFO_0008264 GCST004432 Genome-wide genotyping array 8293 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. RANTES levels 3,421 Finnish ancestry individuals NA NR [10700000] (imputed) 33 CCL5 measurement http://www.ebi.ac.uk/efo/EFO_0005117 GCST004431 Genome-wide genotyping array 3421 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Stem cell factor levels 8,290 Finnish ancestry individuals NA NR [10700000] (imputed) 29 stem Cell Factor measurement http://www.ebi.ac.uk/efo/EFO_0008291 GCST004429 Genome-wide genotyping array 8290 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Stem cell growth factor beta levels 3,682 Finnish ancestry individuals NA NR [10700000] (imputed) 53 stem Cell Growth Factor beta measurement http://www.ebi.ac.uk/efo/EFO_0008292 GCST004428 Genome-wide genotyping array 3682 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Stromal-cell-derived factor 1 alpha levels 5,998 Finnish ancestry individuals NA NR [10700000] (imputed) 26 stromal cell-derived factor 1 alpha measurement http://www.ebi.ac.uk/efo/EFO_0008293 GCST004427 Genome-wide genotyping array 5998 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Tumor necrosis factor alpha levels 3,454 Finnish ancestry individuals NA NR [10700000] (imputed) 19 tumor necrosis factor-alpha measurement http://www.ebi.ac.uk/efo/EFO_0004684 GCST004426 Genome-wide genotyping array 3454 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Tumor necrosis factor beta levels 1,559 Finnish ancestry individuals NA NR [10700000] (imputed) 11 tumor necrosis factor beta measurement http://www.ebi.ac.uk/efo/EFO_0008308 GCST004425 Genome-wide genotyping array 1559 2017-08-04 27989323 Ahola-Olli AV 2016-12-13 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/27989323 Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. TRAIL levels 8,186 Finnish ancestry individuals NA NR [10700000] (imputed) 58 TNF-related apoptosis-inducing ligand measurement http://www.ebi.ac.uk/efo/EFO_0008300 GCST004424 Genome-wide genotyping array 8186 2017-03-24 26965516 Zeng C 2016-03-08 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/26965516 Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk. Colorectal cancer 4,508 East Asian ancestry cases, 16,588 East Asian ancestry controls 11,044 East Asian ancestry cases, 18,036 East Asian ancestry controls Affymetrix, Illumina [~ 4000000] (imputed) 30 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST003799 Genome-wide genotyping array 21096 2017-05-11 27976721 Wang Z 2016-12-15 Nat Commun www.ncbi.nlm.nih.gov/pubmed/27976721 A large-scale genome-wide association and meta-analysis identified four novel susceptibility loci for leprosy. Leprosy 2,743 Chinese ancestry cases, 3,573 Chinese ancestry controls 5,413 Han Chinese ancestry cases, 12,037 Han Chinese ancestry controls Illumina [5546030] (imputed) 13 leprosy http://www.ebi.ac.uk/efo/EFO_0001054 GCST004009 Genome-wide genotyping array 6316 2017-04-20 28011712 Foo JN 2016-12-22 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28011712 Genome-wide association study of Parkinson's disease in East Asians. Parkinson's disease 779 Han Chinese ancestry cases, 13,227 Han Chinese ancestry controls 5,125 Asian ancestry cases, 17,604 Asian ancestry controls Illumina [2402394] (imputed) 4 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST003922 Genome-wide genotyping array 14006 2017-06-26 28371326 Zhu Y 2017-03-30 J Cell Mol Med www.ncbi.nlm.nih.gov/pubmed/28371326 Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study. Metabolic syndrome 862 Han Chinese ancestry cases, 880 Han Chinese ancestry controls 5,514 Han Chinese ancestry cases, 5,464 Han Chinese ancestry controls Illumina [4642479] (imputed) 2 metabolic syndrome http://www.ebi.ac.uk/efo/EFO_0000195 GCST004239 Genome-wide genotyping array 1742 2017-06-26 28371326 Zhu Y 2017-03-30 J Cell Mol Med www.ncbi.nlm.nih.gov/pubmed/28371326 Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study. Fasting blood glucose 862 Han Chinese ancestry cases, 880 Han Chinese ancestry controls 656 Han Chinese ancestry cases, 933 Han Chinese ancestry controls Illumina [4642479] (imputed) 1 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST004240 Genome-wide genotyping array 1742 2017-06-26 28371326 Zhu Y 2017-03-30 J Cell Mol Med www.ncbi.nlm.nih.gov/pubmed/28371326 Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study. Triglyceride levels 862 Han Chinese ancestry cases, 880 Han Chinese ancestry controls 5,514 Han Chinese ancestry cases, 5,464 Han Chinese ancestry controls Illumina [4642479] (imputed) 3 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST004241 Genome-wide genotyping array 1742 2017-06-26 28371326 Zhu Y 2017-03-30 J Cell Mol Med www.ncbi.nlm.nih.gov/pubmed/28371326 Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study. HDL cholesterol 862 Han Chinese ancestry cases, 880 Han Chinese ancestry controls 5,514 Han Chinese ancestry cases, 5,464 Han Chinese ancestry controls Illumina [4642479] (imputed) 1 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST004242 Genome-wide genotyping array 1742 2017-06-26 28371326 Zhu Y 2017-03-30 J Cell Mol Med www.ncbi.nlm.nih.gov/pubmed/28371326 Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study. LDL cholesterol levels 862 Han Chinese ancestry cases, 880 Han Chinese ancestry controls 656 Han Chinese ancestry cases, 933 Han Chinese ancestry controls Illumina [4642479] (imputed) 2 LDL cholesterol change measurement http://www.ebi.ac.uk/efo/EFO_0007804 GCST004243 Genome-wide genotyping array 1742 2017-06-26 28371326 Zhu Y 2017-03-30 J Cell Mol Med www.ncbi.nlm.nih.gov/pubmed/28371326 Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study. Waist-hip ratio 862 Han Chinese ancestry cases, 880 Han Chinese ancestry controls 1,365 Han Chinese ancestry cases, 2,854 Han Chinese ancestry controls Illumina [4642479] (imputed) 0 waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0004343 GCST004244 Genome-wide genotyping array 1742 2017-06-26 28371326 Zhu Y 2017-03-30 J Cell Mol Med www.ncbi.nlm.nih.gov/pubmed/28371326 Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study. Body mass index 862 Han Chinese ancestry cases, 880 Han Chinese ancestry controls 1,365 Han Chinese ancestry cases, 2,854 Han Chinese ancestry controls Illumina [4642479] (imputed) 1 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST004245 Genome-wide genotyping array 1742 2017-06-30 28333968 Nielsen TR 2017-03-23 PLoS One www.ncbi.nlm.nih.gov/pubmed/28333968 A genome-wide association study of thyroid stimulating hormone and free thyroxine in Danish children and adolescents. Plasma thyroid-stimulating hormone levels 1,680 Danish ancestry children and adolescents 2,129 Danish ancestry children and adolescents Illumina [8508717] (imputed) 7 thyroid stimulating hormone measurement http://www.ebi.ac.uk/efo/EFO_0004748 GCST004276 Genome-wide genotyping array 1680 2017-06-30 28333968 Nielsen TR 2017-03-23 PLoS One www.ncbi.nlm.nih.gov/pubmed/28333968 A genome-wide association study of thyroid stimulating hormone and free thyroxine in Danish children and adolescents. Free thyroxine concentration 1,680 Danish ancestry children and adolescents 2,129 Danish ancestry children and adolescents Illumina [8508717] (imputed) 0 thyroxine measurement http://www.ebi.ac.uk/efo/EFO_0005130 GCST004277 Genome-wide genotyping array 1680 2018-09-06 29413154 Shadrin AA 2017-11-26 J Am Acad Child Adolesc Psychiatry www.ncbi.nlm.nih.gov/pubmed/29413154 Novel Loci Associated With Attention-Deficit/Hyperactivity Disorder Are Revealed by Leveraging Polygenic Overlap With Educational Attainment. Attention deficit hyperactivity disorder or educational attainment (years of education) (pleiotropy) 2,064 European and unknown ancestry ADHD trios, 896 European and unknown ancestry ADHD cases, 2,455 European and unknown ancestry controls, 328,917 European ancestry individuals with educational attainment data NA NR [at least 6393963] (imputed) 0 attention deficit hyperactivity disorder, self reported educational attainment http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0004784 GCST006216 Genome-wide genotyping array 334332 2018-05-15 29472232 Li Y 2018-02-22 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/29472232 Genome-Wide Association and Functional Studies Identify SCML4 and THSD7A as Novel Susceptibility Genes for Coronary Artery Disease. Coronary artery disease 280 Han Chinese ancestry cases, 350 Han Chinese ancestry controls 9,764 Han Chinese ancestry cases, 11,434 Han Chinese ancestry controls Affymetrix [314806] (imputed) 4 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST005582 Genome-wide genotyping array 630 2018-04-17 29458411 Chung J 2018-02-20 Alzheimers Res Ther www.ncbi.nlm.nih.gov/pubmed/29458411 Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease. Neuritic plaques or neurofibrillary tangles or cerebral amyloid angiopathy (pleiotropy) 3,135 European ancestry Alzheimer's disease cases, 463 European ancestry controls NA NR [6500000] (imputed) 3 neuritic plaque measurement, cerebral amyloid angiopathy, neurofibrillary tangles measurement http://www.ebi.ac.uk/efo/EFO_0006798, http://www.ebi.ac.uk/efo/EFO_0006790, http://www.ebi.ac.uk/efo/EFO_0006797 GCST005514 Genome-wide genotyping array 3598 2018-04-17 29458411 Chung J 2018-02-20 Alzheimers Res Ther www.ncbi.nlm.nih.gov/pubmed/29458411 Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease. Neuritic plaques or neurofibrillary tangles (pleiotropy) 3,135 European ancestry Alzheimer's disease cases, 463 European ancestry controls NA NR [6500000] (imputed) 4 neuritic plaque measurement, neurofibrillary tangles measurement http://www.ebi.ac.uk/efo/EFO_0006798, http://www.ebi.ac.uk/efo/EFO_0006797 GCST005516 Genome-wide genotyping array 3598 2018-04-17 29458411 Chung J 2018-02-20 Alzheimers Res Ther www.ncbi.nlm.nih.gov/pubmed/29458411 Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease. Neuritic plaques or cerebral amyloid angiopathy (pleiotropy) 3,135 European ancestry Alzheimer's disease cases, 463 European ancestry controls NA NR [6500000] (imputed) 3 neuritic plaque measurement, cerebral amyloid angiopathy http://www.ebi.ac.uk/efo/EFO_0006798, http://www.ebi.ac.uk/efo/EFO_0006790 GCST005515 Genome-wide genotyping array 3598 2018-04-17 29458411 Chung J 2018-02-20 Alzheimers Res Ther www.ncbi.nlm.nih.gov/pubmed/29458411 Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease. Neurofibrillary tangles or cerebral amyloid angiopathy (pleiotropy) 3,135 European ancestry Alzheimer's diseases cases, 463 European ancestry controls NA NR [6500000] (imputed) 2 cerebral amyloid angiopathy, neurofibrillary tangles measurement http://www.ebi.ac.uk/efo/EFO_0006790, http://www.ebi.ac.uk/efo/EFO_0006797 GCST005517 Genome-wide genotyping array 3598 2017-02-24 27225129 Okbay A 2016-05-26 Nature www.ncbi.nlm.nih.gov/pubmed/27225129 Genome-wide association study identifies 74 loci associated with educational attainment. Educational attainment (years of education) 405,072 European ancestry individuals NA Affymetrix, Illumina, Perlegen [~ 9300000] (imputed) 162 self reported educational attainment http://www.ebi.ac.uk/efo/EFO_0004784 GCST003676 Genome-wide genotyping array 405072 2017-02-25 27225129 Okbay A 2016-05-26 Nature www.ncbi.nlm.nih.gov/pubmed/27225129 Genome-wide association study identifies 74 loci associated with educational attainment. Educational attainment (college completion) 280,007 European ancestry individuals NA Affymetrix, Illumina, Perlegen [~ 9300000] (imputed) 34 self reported educational attainment http://www.ebi.ac.uk/efo/EFO_0004784 GCST003677 Genome-wide genotyping array 280007 2017-05-24 28043905 Nicoletti P 2016-12-30 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/28043905 Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. Drug-induced liver injury (terbinafine) 14 European ancestry cases, 10,588 European ancestry controls. NA Illumina [505740] (imputed) 1 drug-induced liver injury, response to terbinafine http://www.ebi.ac.uk/efo/EFO_0004228, http://www.ebi.ac.uk/efo/EFO_0007923 GCST004078 Genome-wide genotyping array 10602 2017-05-24 28043905 Nicoletti P 2016-12-30 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/28043905 Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. Drug-induced hepatocellular liver injury 474 European ancestry cases, 10,588 European ancestry controls NA Illumina [505740] (imputed) 1 drug-induced liver injury http://www.ebi.ac.uk/efo/EFO_0004228 GCST004079 Genome-wide genotyping array 11062 2017-05-24 28043905 Nicoletti P 2016-12-30 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/28043905 Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. Drug-induced liver injury (statins) 59 European ancestry cases, 10,588 European ancestry controls NA Illumina [505740] (imputed) 1 response to statin, drug-induced liver injury http://purl.obolibrary.org/obo/GO_0036273, http://www.ebi.ac.uk/efo/EFO_0004228 GCST004080 Genome-wide genotyping array 10647 2017-05-24 28043905 Nicoletti P 2016-12-30 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/28043905 Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. Drug-induced cholestatic/mixed liver injury 323 European ancestry cases, 10,588 European ancestry controls. NA Illumina [505740] (imputed) 3 drug-induced liver injury http://www.ebi.ac.uk/efo/EFO_0004228 GCST004081 Genome-wide genotyping array 10911 2017-05-24 28043905 Nicoletti P 2016-12-30 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/28043905 Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. Drug-induced liver injury (nitrofurantoin) 64 European ancestry cases, 10,588 European ancestry controls NA Illumina [505740] (imputed) 4 response to nitrofurantoin, drug-induced liver injury http://www.ebi.ac.uk/efo/EFO_0007921, http://www.ebi.ac.uk/efo/EFO_0004228 GCST004082 Genome-wide genotyping array 10652 2017-05-24 28043905 Nicoletti P 2016-12-30 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/28043905 Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. Drug-induced liver injury (diclofenac) 67 European ancestry cases, 10,588 European ancestry controls NA Illumina [505740] (imputed) 4 response to diclofenac, drug-induced liver injury http://www.ebi.ac.uk/efo/EFO_0007919, http://www.ebi.ac.uk/efo/EFO_0004228 GCST004083 Genome-wide genotyping array 10655 2017-05-24 28043905 Nicoletti P 2016-12-30 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/28043905 Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. Drug-induced liver injury (anti-tuberculosis drugs) 67 European ancestry cases, 10,588 European ancestry controls NA Illumina [505740] (imputed) 3 response to anti-tuberculosis drug, drug-induced liver injury http://www.ebi.ac.uk/efo/EFO_0007918, http://www.ebi.ac.uk/efo/EFO_0004228 GCST004084 Genome-wide genotyping array 10655 2017-05-24 28043905 Nicoletti P 2016-12-30 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/28043905 Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. Drug-induced liver injury (fluoroquinolones) 43 European ancestry cases, 10,588 European ancestry controls NA Illumina [505740] (imputed) 4 response to fluoroquinolones, drug-induced liver injury http://www.ebi.ac.uk/efo/EFO_0007920, http://www.ebi.ac.uk/efo/EFO_0004228 GCST004085 Genome-wide genotyping array 10631 2017-05-24 28043905 Nicoletti P 2016-12-30 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/28043905 Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. Drug-induced liver injury (nonsteroidal anti-inflammatory drugs) 144 European ancestry cases, 10,588 European ancestry controls NA Illumina [505740] (imputed) 4 response to non-steroidal anti-inflammatory, drug-induced liver injury http://www.ebi.ac.uk/efo/EFO_0005533, http://www.ebi.ac.uk/efo/EFO_0004228 GCST004087 Genome-wide genotyping array 10732 2017-05-24 28043905 Nicoletti P 2016-12-30 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/28043905 Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. Drug-induced liver injury 862 European ancestry cases and 10,588 European ancestry controls NA Illumina [505740] (imputed) 4 drug-induced liver injury http://www.ebi.ac.uk/efo/EFO_0004228 GCST004086 Genome-wide genotyping array 11450 2017-05-15 27846195 Li Q 2016-11-11 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/27846195 Genome-wide association study of paliperidone efficacy. Response to paliperidone in schizophrenia (positive Marder score) 1,390 European ancestry cases NA Illumina [~ 9000000] (imputed) 63 response to paliperidone, schizophrenia symptom severity measurement http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927 GCST004040 Genome-wide genotyping array 1390 2017-05-15 27846195 Li Q 2016-11-11 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/27846195 Genome-wide association study of paliperidone efficacy. Response to paliperidone in schizophrenia (negative Marder score) 1,390 European ancestry cases NA Illumina [~ 9000000] (imputed) 66 response to paliperidone, schizophrenia symptom severity measurement http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927 GCST004041 Genome-wide genotyping array 1390 2017-05-15 27846195 Li Q 2016-11-11 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/27846195 Genome-wide association study of paliperidone efficacy. Response to paliperidone in schizophrenia (PANSS score) 1,390 European ancestry individuals NA Illumina [~ 9000000] (imputed) 64 response to paliperidone, schizophrenia symptom severity measurement http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927 GCST004042 Genome-wide genotyping array 1390 2017-05-15 27846195 Li Q 2016-11-11 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/27846195 Genome-wide association study of paliperidone efficacy. Response to paliperidone in schizophrenia (Multivariate) 1,390 European ancestry individuals NA Illumina [~ 9000000] (imputed) 26 response to paliperidone, schizophrenia symptom severity measurement http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927 GCST004043 Genome-wide genotyping array 1390 2017-05-15 27846195 Li Q 2016-11-11 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/27846195 Genome-wide association study of paliperidone efficacy. Response to paliperidone in schizophrenia (CGI-S score) 1,390 European ancestry cases NA Illumina [~ 9000000] (imputed) 30 response to paliperidone, schizophrenia symptom severity measurement http://www.ebi.ac.uk/efo/EFO_0007925, http://www.ebi.ac.uk/efo/EFO_0007927 GCST004039 Genome-wide genotyping array 1390 2017-04-04 27723756 Wang J 2016-10-10 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27723756 Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota. Gut microbiota (beta diversity) 1,812 European ancestry individuals 371 European ancestry individuals Affymetrix, Illumina [6344846] (imputed) 15 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST003876 Genome-wide genotyping array 1812 2017-04-04 27723756 Wang J 2016-10-10 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27723756 Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota. Gut microbiota (bacterial taxa) 1,812 European ancestry individuals NA Affymetrix, Illumina [6344846] (imputed) 51 gut microbiome measurement, taxonomic microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874, http://www.ebi.ac.uk/efo/EFO_0007883 GCST003875 Genome-wide genotyping array 1812 2017-03-21 27656708 Zhang W 2016-09-22 Thromb Haemost www.ncbi.nlm.nih.gov/pubmed/27656708 Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels. L-arginine levels 901 European ancestry individuals, 1,394 Indian Asian ancestry individuals 1,000 European ancestry individuals, 2,981 individuals Illumina [~ 8000000] (imputed) 2 L-arginine measurement http://www.ebi.ac.uk/efo/EFO_0006524 GCST003793 Genome-wide genotyping array 2295 2017-05-12 28011674 Ruhle F 2016-12-23 Blood www.ncbi.nlm.nih.gov/pubmed/28011674 Rare genetic variants in SMAP1, B3GAT2, and RIMS1 contribute to pediatric venous thromboembolism. Venous thromboembolism 212 European ancestry trios NA Illumina [529944] 2 venous thromboembolism http://www.ebi.ac.uk/efo/EFO_0004286 GCST004012 Genome-wide genotyping array 212 2017-04-21 28011148 Zhang M 2016-12-21 J Invest Dermatol www.ncbi.nlm.nih.gov/pubmed/28011148 A Genome-Wide Association Study of Basal Transepidermal Water Loss Finds that Variants at 9q34.3 Are Associated with Skin Barrier Function. Trans-epidermal water loss 611 Han Chinese ancestry individuals 366 Han Chinese ancestry individuals Illumina [7998413] (imputed) 1 skin barrier function measurement http://www.ebi.ac.uk/efo/EFO_0007891 GCST003940 Genome-wide genotyping array 611 2017-09-20 28254843 Qi Q 2017-03-02 Diabetes www.ncbi.nlm.nih.gov/pubmed/28254843 Genetics of Type 2 Diabetes in U.S. Hispanic/Latino Individuals: Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Type 2 diabetes 2,499 Hispanic/Latino ancestry cases, 5,247 Hispanic/Latino ancestry controls NA Illumina [NR] (imputed) 8 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST004758 Genome-wide genotyping array 7746 2017-07-13 28374850 Ellinghaus E 2017-04-04 Sci Rep www.ncbi.nlm.nih.gov/pubmed/28374850 Genome-wide association analysis for chronic venous disease identifies EFEMP1 and KCNH8 as susceptibility loci. Chronic venous disease 323 German ancestry cases and 4,619 German ancestry controls 1,946 German ancestry cases and 3,146 German ancestry controls Affymetrix [1934349] (imputed) 3 chronic venous insufficiency, Varicose veins http://www.ebi.ac.uk/efo/EFO_0007940, http://purl.obolibrary.org/obo/HP_0002619 GCST004343 Genome-wide genotyping array 4942 2017-05-23 28076899 Taylor KE 2017-01-11 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/28076899 Genome-Wide Association Analysis Reveals Genetic Heterogeneity of Sjögren's Syndrome According to Ancestry. Sjögren's syndrome 460 Asian ancestry cases, 1125 Asian ancestry controls NA Illumina [302688] 2 Sjogren syndrome http://www.ebi.ac.uk/efo/EFO_0000699 GCST004062 Genome-wide genotyping array 1585 2017-05-23 28076899 Taylor KE 2017-01-11 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/28076899 Genome-Wide Association Analysis Reveals Genetic Heterogeneity of Sjögren's Syndrome According to Ancestry. Sjögren's syndrome 585 European ancestry cases, up to 51 African ancestry cases, up to 164 Hispanic/Native american cases, up to 570 Asian ancestry cases, up to 59 cases, 3,546 European ancestry controls, 495 African ancestry controls, 237 Hispanic/Native American controls, 306 Asian ancestry controls, 148 controls. NA Illumina [1444884] 20 Sjogren syndrome http://www.ebi.ac.uk/efo/EFO_0000699 GCST004061 Genome-wide genotyping array 6161 2017-07-03 28334814 Zhu Z 2017-02-28 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28334814 Genome-wide association study identifies novel susceptible loci and highlights Wnt/beta-catenin pathway in the development of adolescent idiopathic scoliosis. Adolescent idiopathic scoliosis up to 1,456 Han Chinese ancestry cases, up to 2,104 Han Chinese ancestry controls up to 4,450 Han Chinese ancestry cases, up to 6,014 Han Chinese ancestry controls Affymetrix [435183] 8 adolescent idiopathic scoliosis http://www.ebi.ac.uk/efo/EFO_0005423 GCST004288 Genome-wide genotyping array 3560 2017-06-12 28334792 Nongmaithem SS 2017-02-27 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/28334792 GWAS identifies population-specific new regulatory variants in FUT6 associated with plasma B12 concentrations in Indians. Vitamin B12 levels 1,001 Indo-European ancestry adults 1,713 Indo-European ancestry adults, 690 Indo-European ancestry children, 481 Dravidian ancestry adults, 534 Dravidian ancestry children Affymetrix [8900000] (imputed) 4 vitamin B12 measurement http://www.ebi.ac.uk/efo/EFO_0004620 GCST004161 Genome-wide genotyping array 1001 2018-04-20 29478026 Shahin MH 2018-02-24 J Am Heart Assoc www.ncbi.nlm.nih.gov/pubmed/29478026 Genome-Wide Association Approach Identified Novel Genetic Predictors of Heart Rate Response to β-Blockers. Heart rate response to beta blockers (atenolol monotherapy) 228 European American hypertensive individuals, 146 African American hypertensive individuals NA Illumina [at least 1100000] (imputed) 29 response to beta blocker, heart rate http://www.ebi.ac.uk/efo/EFO_0007766, http://www.ebi.ac.uk/efo/EFO_0004326 GCST005521 Genome-wide genotyping array 374 2018-04-20 29478026 Shahin MH 2018-02-24 J Am Heart Assoc www.ncbi.nlm.nih.gov/pubmed/29478026 Genome-Wide Association Approach Identified Novel Genetic Predictors of Heart Rate Response to β-Blockers. Heart rate response to beta blockers (atenolol add-on therapy) 198 European American hypertensive individuals, 127 African American hypertensive individuals NA Illumina [at least 1100000] (imputed) 33 response to beta blocker, heart rate http://www.ebi.ac.uk/efo/EFO_0007766, http://www.ebi.ac.uk/efo/EFO_0004326 GCST005520 Genome-wide genotyping array 325 2018-04-20 29478026 Shahin MH 2018-02-24 J Am Heart Assoc www.ncbi.nlm.nih.gov/pubmed/29478026 Genome-Wide Association Approach Identified Novel Genetic Predictors of Heart Rate Response to β-Blockers. Heart rate response to beta blockers 426 European American hypertensive individuals, 273 African American hypertensive individuals 200 European American hypertensive individuals, 168 African American hypertensive individuals Illumina [at least 1100000] (imputed) 2 response to beta blocker, heart rate http://www.ebi.ac.uk/efo/EFO_0007766, http://www.ebi.ac.uk/efo/EFO_0004326 GCST005519 Genome-wide genotyping array 699 2017-09-05 28644415 Guenard F 2017-06-23 Nutrients www.ncbi.nlm.nih.gov/pubmed/28644415 Genome-Wide Association Study of Dietary Pattern Scores. Western dietary pattern 141 individuals NA Illumina [2668805] 23 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST004640 Genome-wide genotyping array 141 2017-09-05 28644415 Guenard F 2017-06-23 Nutrients www.ncbi.nlm.nih.gov/pubmed/28644415 Genome-Wide Association Study of Dietary Pattern Scores. Prudent dietary pattern 141 individuals NA Illumina [2668805] 42 diet measurement http://www.ebi.ac.uk/efo/EFO_0008111 GCST004639 Genome-wide genotyping array 141 2017-06-01 28107422 de Vries PS 2017-01-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/28107422 Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study. Fibrinogen levels 91,953 European ancestry individuals (imputed to HapMap) NA Affymetrix, Illumina [2749429] (imputed) 36 fibrinogen measurement http://www.ebi.ac.uk/efo/EFO_0004623 GCST004122 Genome-wide genotyping array 91953 2017-06-01 28107422 de Vries PS 2017-01-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/28107422 Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study. Fibrinogen levels 91,953 European ancestry individuals (imputed to 1000 Genomes) NA Affymetrix, Illumina [10883314] (imputed) 36 fibrinogen measurement http://www.ebi.ac.uk/efo/EFO_0004623 GCST004121 Genome-wide genotyping array 92953 2017-08-07 28346442 Phelan CM 2017-03-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28346442 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. Low-grade serous and serous borderline ovarian cancer 2,966 European ancestry cases, 40,941 European ancestry controls NA Illumina [11595112] (imputed) 12 ovarian serous carcinoma http://www.ebi.ac.uk/efo/EFO_1001516 GCST004481 Genome-wide genotyping array 43907 2017-08-03 28346442 Phelan CM 2017-03-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28346442 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. Ovarian cancer in BRCA2 mutation carriers 954 European ancestry carrier cases, 11,458 European ancestry carrier controls NA Illumina [11595112] (imputed) 2 ovarian carcinoma http://www.ebi.ac.uk/efo/EFO_0001075 GCST004416 Genome-wide genotyping array 12412 2017-08-04 28346442 Phelan CM 2017-03-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28346442 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. Epithelial ovarian cancer 16,924 European ancestry cases, 68,502 European ancestry controls NA Illumina [11595112] (imputed) 23 ovarian carcinoma http://www.ebi.ac.uk/efo/EFO_0001075 GCST004462 Genome-wide genotyping array 85426 2017-08-03 28346442 Phelan CM 2017-03-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28346442 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. Ovarian clear cell cancer 1,366 European ancestry cases, 40,941 European ancestry controls NA Illumina [11595112] (imputed) 2 ovarian clear cell adenocarcinoma http://www.ebi.ac.uk/efo/EFO_1000042 GCST004417 Genome-wide genotyping array 42307 2017-08-03 28346442 Phelan CM 2017-03-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28346442 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. Endometrioid ovarian cancer 2,810 European ancestry cases, 40,941 European ancestry controls NA Illumina [11595112] (imputed) 1 ovarian endometrioid carcinoma http://www.ebi.ac.uk/efo/EFO_1001515 GCST004418 Genome-wide genotyping array 43751 2017-08-03 28346442 Phelan CM 2017-03-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28346442 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. Mucinous ovarian carcinoma 2,566 European ancestry cases, 40,941 European ancestry controls NA Illumina [11595112] (imputed) 7 ovarian mucinous adenocarcinoma http://www.ebi.ac.uk/efo/EFO_0006462 GCST004419 Genome-wide genotyping array 43507 2017-08-07 28346442 Phelan CM 2017-03-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28346442 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. Serous invasive ovarian cancer 14,049 European ancestry cases, 40,941 European ancestry controls NA Illumina [11595112] (imputed) 21 ovarian serous carcinoma http://www.ebi.ac.uk/efo/EFO_1001516 GCST004478 Genome-wide genotyping array 54990 2017-08-07 28346442 Phelan CM 2017-03-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28346442 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. Serous borderline ovarian cancer 1,954 European ancestry cases, 40,941 European ancestry controls NA Illumina [11595112] (imputed) 10 ovarian serous carcinoma http://www.ebi.ac.uk/efo/EFO_1001516 GCST004479 Genome-wide genotyping array 42895 2017-08-07 28346442 Phelan CM 2017-03-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28346442 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. High-grade serous ovarian cancer 13,037 European ancestry cases, 40,941 European ancestry controls NA Illumina [11595112] (imputed) 21 ovarian serous carcinoma http://www.ebi.ac.uk/efo/EFO_1001516 GCST004480 Genome-wide genotyping array 53978 2017-08-04 28346442 Phelan CM 2017-03-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28346442 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. Low-grade serous ovarian cancer 1,012 European ancestry cases, 40,941 European ancestry controls NA Illumina [11595112] (imputed) 1 ovarian serous carcinoma http://www.ebi.ac.uk/efo/EFO_1001516 GCST004461 Genome-wide genotyping array 41953 2017-08-03 28346442 Phelan CM 2017-03-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28346442 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. Ovarian cancer in BRCA1 mutation carriers 2,933 European ancestry carrier cases, 16,103 European ancestry carrier controls NA Illumina [11595112] (imputed) 4 ovarian carcinoma http://www.ebi.ac.uk/efo/EFO_0001075 GCST004414 Genome-wide genotyping array 19036 2017-08-03 28346442 Phelan CM 2017-03-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28346442 Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. Invasive epithelial ovarian cancer 22,406 European ancestry cases, 40,941 European ancestry controls NA Illumina [11595112] (imputed) 19 ovarian carcinoma http://www.ebi.ac.uk/efo/EFO_0001075 GCST004415 Genome-wide genotyping array 63347 2020-08-20 32372009 de Las Fuentes L 2020-05-05 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32372009 Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci. Systolic blood pressure x educational attainment (some college) interaction (2df) 27,617 European ancestry individuals with some college education, 20,253 European ancestry individuals without college education, 8,128 African ancestry individuals with some college education, 8,537 African ancestry individuals without college education, 1,138 Asian ancestry individuals with some college education, 10,214 Asian ancestry individuals without college education, 1,869 Hispanic/Latin American individuals with some college education, 3,276 Hispanic/Latin American individuals without college education 131,584 European ancestry individuals with some college education, 110,940 European ancestry individuals without college education, 1,494 African ancestry individuals with some college education, 5,704 African ancestry individuals without college education, 2,339 Asian ancestry individuals with some college education, 8,567 Asian ancestry individuals without college education, 4,133 Hispanic individuals with some college education, 7,498 Hispanic individuals without college education Affymetrix, Illumina [~ 18800000] (imputed) 7 systolic blood pressure, self reported educational attainment http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004784 GCST010426 Genome-wide genotyping array 81032 2020-08-20 32372009 de Las Fuentes L 2020-05-05 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32372009 Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci. Systolic blood pressure x educational attainment (graduated college) interaction (2df) 27,367 European ancestry college graduated individuals, 51,673 European ancestry non-college graduated individuals, 3,605 African ancestry college graduated individuals, 13,060 African ancestry non-college graduated individuals, 291 Asian ancestry college graduated individuals, 457 Asian ancestry non-college graduated individuals, 786 Hispanic/Latin American college graduated individuals, 4,359 Hispanic/Latin American non-college graduated individuals 67,506 European ancestry college graduated individuals, 189,531 European ancestry non-college graduated individuals, 781 African ancestry college graduated individuals, 6,417 African ancestry non-college graduated individuals, 651 Asian ancestry college graduated individuals, 5,296 Asian ancestry non-college graduated individuals, 1,703 Hispanic college graduated individuals, 9,928 Hispanic non-college graduated individuals Affymetrix, Illumina [~ 18800000] (imputed) 2 systolic blood pressure, self reported educational attainment http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004784 GCST010425 Genome-wide genotyping array 101598 2020-08-20 32372009 de Las Fuentes L 2020-05-05 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32372009 Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci. Diastolic blood pressure x educational attainment (some college) interaction (2df) 27,617 European ancestry individuals with some college education, 20,253 European ancestry individuals without college education, 8,128 African ancestry individuals with some college education, 8,537 African ancestry individuals without college education, 1,138 Asian ancestry individuals with some college education, 10,214 Asian ancestry individuals without college education, 1,869 Hispanic/Latin American individuals with some college education, 3,276 Hispanic/Latin American individuals without college education 131,584 European ancestry individuals with some college education, 110,940 European ancestry individuals without college education, 1,494 African ancestry individuals with some college education, 5,704 African ancestry individuals without college education, 2,339 Asian ancestry individuals with some college education, 8,567 Asian ancestry individuals without college education, 4,133 Hispanic individuals with some college education, 7,498 Hispanic individuals without college education Affymetrix, Illumina [~ 18800000] (imputed) 1 diastolic blood pressure, self reported educational attainment http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004784 GCST010424 Genome-wide genotyping array 81032 2020-08-20 32372009 de Las Fuentes L 2020-05-05 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32372009 Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci. Diastolic blood pressure x educational attainment (graduated college) interaction (2df) 27,367 European ancestry college graduated individuals, 51,673 European ancestry non-college graduated individuals, 3,605 African ancestry college graduated individuals, 13,060 African ancestry non-college graduated individuals, 291 Asian ancestry college graduated individuals, 457 Asian ancestry non-college graduated individuals, 786 Hispanic/Latin American college graduated individuals, 4,359 Hispanic/Latin American non-college graduated individuals 67,506 European ancestry college graduated individuals, 189,531 European ancestry non-college graduated individuals, 781 African ancestry college graduated individuals, 6,417 African ancestry non-college graduated individuals, 651 Asian ancestry college graduated individuals, 5,296 Asian ancestry non-college graduated individuals, 1,703 Hispanic college graduated individuals, 9,928 Hispanic non-college graduated individuals Affymetrix, Illumina [~ 18800000] (imputed) 4 diastolic blood pressure, self reported educational attainment http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004784 GCST010423 Genome-wide genotyping array 101598 2020-08-20 32372009 de Las Fuentes L 2020-05-05 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32372009 Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci. Mean arterial pressure x educational attainment (some college) interaction (2df) 27,617 European ancestry individuals with some college education, 20,253 European ancestry individuals without college education, 8,128 African ancestry individuals with some college education, 8,537 African ancestry individuals without college education, 1,138 Asian ancestry individuals with some college education, 10,214 Asian ancestry individuals without college education, 1,869 Hispanic/Latin American individuals with some college education, 3,276 Hispanic/Latin American individuals without college education 131,584 European ancestry individuals with some college education, 110,940 European ancestry individuals without college education, 1,494 African ancestry individuals with some college education, 5,704 African ancestry individuals without college education, 2,339 Asian ancestry individuals with some college education, 8,567 Asian ancestry individuals without college education, 4,133 Hispanic individuals with some college education, 7,498 Hispanic individuals without college education Affymetrix, Illumina [~ 18800000] (imputed) 3 mean arterial pressure, self reported educational attainment http://www.ebi.ac.uk/efo/EFO_0006340, http://www.ebi.ac.uk/efo/EFO_0004784 GCST010422 Genome-wide genotyping array 81032 2020-08-20 32372009 de Las Fuentes L 2020-05-05 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32372009 Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci. Mean arterial pressure x educational attainment (graduated college) interaction (2df) 27,367 European ancestry college graduated individuals, 51,673 European ancestry non-college graduated individuals, 3,605 African ancestry college graduated individuals, 13,060 African ancestry non-college graduated individuals, 291 Asian ancestry college graduated individuals, 457 Asian ancestry non-college graduated individuals, 786 Hispanic/Latin American college graduated individuals, 4,359 Hispanic/Latin American non-college graduated individuals 67,506 European ancestry college graduated individuals, 189,531 European ancestry non-college graduated individuals, 781 African ancestry college graduated individuals, 6,417 African ancestry non-college graduated individuals, 651 Asian ancestry college graduated individuals, 5,296 Asian ancestry non-college graduated individuals, 1,703 Hispanic college graduated individuals, 9,928 Hispanic non-college graduated individuals Affymetrix, Illumina [~ 18800000] (imputed) 2 mean arterial pressure, self reported educational attainment http://www.ebi.ac.uk/efo/EFO_0006340, http://www.ebi.ac.uk/efo/EFO_0004784 GCST010421 Genome-wide genotyping array 101598 2020-08-20 32372009 de Las Fuentes L 2020-05-05 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32372009 Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci. Pulse pressure x educational attainment (some college) interaction (2df) 27,617 European ancestry individuals with some college education, 20,253 European ancestry individuals without college education, 8,128 African ancestry individuals with some college education, 8,537 African ancestry individuals without college education, 1,138 Asian ancestry individuals with some college education, 10,214 Asian ancestry individuals without college education, 1,869 Hispanic/Latin American individuals with some college education, 3,276 Hispanic/Latin American individuals without college education 131,584 European ancestry individuals with some college education, 110,940 European ancestry individuals without college education, 1,494 African ancestry individuals with some college education, 5,704 African ancestry individuals without college education, 2,339 Asian ancestry individuals with some college education, 8,567 Asian ancestry individuals without college education, 4,133 Hispanic individuals with some college education, 7,498 Hispanic individuals without college education Affymetrix, Illumina [~ 18800000] (imputed) 4 pulse pressure measurement, self reported educational attainment http://www.ebi.ac.uk/efo/EFO_0005763, http://www.ebi.ac.uk/efo/EFO_0004784 GCST010420 Genome-wide genotyping array 81032 2020-08-20 32372009 de Las Fuentes L 2020-05-05 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32372009 Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci. Pulse pressure x educational attainment (graduated college) interaction (2df) 27,367 European ancestry college graduated individuals, 51,673 European ancestry non-college graduated individuals, 3,605 African ancestry college graduated individuals, 13,060 African ancestry non-college graduated individuals, 291 Asian ancestry college graduated individuals, 457 Asian ancestry non-college graduated individuals, 786 Hispanic/Latin American college graduated individuals, 4,359 Hispanic/Latin American non-college graduated individuals 67,506 European ancestry college graduated individuals, 189,531 European ancestry non-college graduated individuals, 781 African ancestry college graduated individuals, 6,417 African ancestry non-college graduated individuals, 651 Asian ancestry college graduated individuals, 5,296 Asian ancestry non-college graduated individuals, 1,703 Hispanic college graduated individuals, 9,928 Hispanic non-college graduated individuals Affymetrix, Illumina [~ 18800000] (imputed) 0 pulse pressure measurement, self reported educational attainment http://www.ebi.ac.uk/efo/EFO_0005763, http://www.ebi.ac.uk/efo/EFO_0004784 GCST010419 Genome-wide genotyping array 101598 2020-10-27 32363570 Giri AK 2020-05-04 Mol Genet Genomics www.ncbi.nlm.nih.gov/pubmed/32363570 Multifaceted genome-wide study identifies novel regulatory loci in SLC22A11 and ZNF45 for body mass index in Indians. Body mass index 1,142 Indo-European Indian ancestry individuals 6,117 Indo-European Indian ancestry individuals Illumina [537246] 3 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST010721 Genome-wide genotyping array 1142 2019-05-10 30664875 Cirulli ET 2019-01-18 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/30664875 A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury. Drug-induced liver injury 1,806 European ancestry cases, 133 African American cases, 109 Hispanic ancestry cases, 10,397 European ancestry controls, 1,314 African American controls, 718 Hispanic ancestry controls 113 Icelandic ancestry cases, 239,304 Icelandic ancestry controls Affymetrix, Illumina [3622749] (imputed) 0 drug-induced liver injury http://www.ebi.ac.uk/efo/EFO_0004228 GCST007774 Genome-wide genotyping array 14477 2020-09-17 32581322 Kakuta Y 2020-06-24 Sci Rep www.ncbi.nlm.nih.gov/pubmed/32581322 An Integrated Genomic and Transcriptomic Analysis Reveals Candidates of Susceptibility Genes for Crohn's Disease in Japanese Populations. Crohn's disease 713 Japanese ancestry cases, 2,063 Japanese ancestry controls NA NR [7424691] (imputed) 24 Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000384 GCST010577 Genome-wide genotyping array 2776 2020-09-15 32564518 Ye J 2020-06-20 Clin Transl Med www.ncbi.nlm.nih.gov/pubmed/32564518 Association between herpes simplex virus 1 exposure and the risk of depression in UK Biobank. Depressive symptoms x herpes simplex 1 infection interaction 2,839 British ancestry individuals NA NR [NR] (imputed) 8 depressive symptom measurement, herpes virus seropositivity http://www.ebi.ac.uk/efo/EFO_0007006, http://www.ebi.ac.uk/efo/EFO_0007036 GCST010562 Genome-wide genotyping array 2839 2020-09-15 32564518 Ye J 2020-06-20 Clin Transl Med www.ncbi.nlm.nih.gov/pubmed/32564518 Association between herpes simplex virus 1 exposure and the risk of depression in UK Biobank. Depression x herpes simplex 1 infection interaction 1,464 British ancestry cases, 1,487 British ancestry controls NA NR [NR] (imputed) 5 unipolar depression, herpes virus seropositivity http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0007036 GCST010561 Genome-wide genotyping array 2951 2020-09-16 32572145 Kawafune K 2020-06-22 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32572145 Strong association between the 12q24 locus and sweet taste preference in the Japanese population revealed by genome-wide meta-analysis. Sweet taste preference 12,312 Japanese ancestry individuals NA Illumina [5299861] (imputed) 13 sweet liking measurement http://www.ebi.ac.uk/efo/EFO_0010156 GCST010572 Genome-wide genotyping array 12312 2020-09-15 32573827 Huang YH 2020-06-23 Aliment Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/32573827 Large-scale genome-wide association study identifies HLA class II variants associated with chronic HBV infection: a study from Taiwan Biobank. Chronic hepatitis B infection 1,810 East Asian cases, 9,002 East Asian seropositive controls 648 East Asian cases, 3,190 East Asian seropositive controls Affymetrix [583383] 2 chronic hepatitis B virus infection http://www.ebi.ac.uk/efo/EFO_0004239 GCST010560 Genome-wide genotyping array 10812 2020-06-23 24531328 Kozlitina J 2014-02-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/24531328 Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease. Nonalcoholic fatty liver disease 2,448 African American individuals, 1,365 European ancestry individuals, 753 Hispanic individuals, 141 other ancestries individuals NA Illumina [138374] 2 non-alcoholic fatty liver disease http://www.ebi.ac.uk/efo/EFO_0003095 GCST010096 Exome genotyping array [Exome array] 4707 2020-09-17 32624584 Yousaf A 2020-07-05 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32624584 Quantitative genome-wide association study of six phenotypic subdomains identifies novel genome-wide significant variants in autism spectrum disorder. Autism spectrum disorders (restricted interests) 2,509 individuals NA Illumina [6900500] (imputed) 0 autism spectrum disorder symptom http://www.ebi.ac.uk/efo/EFO_0005426 GCST010585 Genome-wide genotyping array 2509 2020-09-17 32624584 Yousaf A 2020-07-05 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32624584 Quantitative genome-wide association study of six phenotypic subdomains identifies novel genome-wide significant variants in autism spectrum disorder. Autism spectrum disorders (social interaction) 2,509 individuals NA Illumina [6900500] (imputed) 4 autism spectrum disorder symptom http://www.ebi.ac.uk/efo/EFO_0005426 GCST010584 Genome-wide genotyping array 2509 2020-09-17 32624584 Yousaf A 2020-07-05 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32624584 Quantitative genome-wide association study of six phenotypic subdomains identifies novel genome-wide significant variants in autism spectrum disorder. Autism spectrum disorders (joint attention) 2,509 individuals NA Illumina [6900500] (imputed) 0 autism spectrum disorder symptom http://www.ebi.ac.uk/efo/EFO_0005426 GCST010583 Genome-wide genotyping array 2509 2020-09-17 32624584 Yousaf A 2020-07-05 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32624584 Quantitative genome-wide association study of six phenotypic subdomains identifies novel genome-wide significant variants in autism spectrum disorder. Autism spectrum disorders (peer interaction) 2,509 individuals NA Illumina [6900500] (imputed) 3 autism spectrum disorder symptom http://www.ebi.ac.uk/efo/EFO_0005426 GCST010582 Genome-wide genotyping array 2509 2020-09-17 32624584 Yousaf A 2020-07-05 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32624584 Quantitative genome-wide association study of six phenotypic subdomains identifies novel genome-wide significant variants in autism spectrum disorder. Autism spectrum disorders (nonverbal communication) 2,509 individuals NA Illumina [6900500] (imputed) 0 autism spectrum disorder symptom http://www.ebi.ac.uk/efo/EFO_0005426 GCST010581 Genome-wide genotyping array 2509 2020-09-17 32624584 Yousaf A 2020-07-05 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32624584 Quantitative genome-wide association study of six phenotypic subdomains identifies novel genome-wide significant variants in autism spectrum disorder. Autism spectrum disorders (repetitive sensory-motor behaviour) 2,509 individuals NA Illumina [6900500] (imputed) 4 autism spectrum disorder symptom http://www.ebi.ac.uk/efo/EFO_0005426 GCST010580 Genome-wide genotyping array 2509 2020-07-03 32612638 Al-Khelaifi F 2020-06-16 Front Genet www.ncbi.nlm.nih.gov/pubmed/32612638 Genome-Wide Association Study Reveals a Novel Association Between MYBPC3 Gene Polymorphism, Endurance Athlete Status, Aerobic Capacity and Steroid Metabolism. World class endurance athleticism 662 European ancestry cases, 134 European ancestry controls NA Illumina [341385] 1 athletic endurance measurement http://www.ebi.ac.uk/efo/EFO_0007818 GCST010116 Targeted genotyping array [Drug-core array] 796 2020-07-20 32595297 Kweon K 2018-04-01 Soa Chongsonyon Chongsin Uihak www.ncbi.nlm.nih.gov/pubmed/32595297 Genome-Wide Analysis Reveals Four Novel Loci for Attention-Deficit Hyperactivity Disorder in Korean Youths. Attention deficit hyperactivity disorder (inattention symptoms) 71 Korean ancestry ADHD child cases, 64 Korean ancestry child controls NA Affymetrix [525356] 2 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST010221 Genome-wide genotyping array 135 2020-07-20 32595297 Kweon K 2018-04-01 Soa Chongsonyon Chongsin Uihak www.ncbi.nlm.nih.gov/pubmed/32595297 Genome-Wide Analysis Reveals Four Novel Loci for Attention-Deficit Hyperactivity Disorder in Korean Youths. Attention deficit hyperactivity disorder (hyperactivity-impulsivity symptoms) 71 Korean ancestry ADHD child cases, 64 Korean ancestry child controls NA Affymetrix [525356] 5 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST010220 Genome-wide genotyping array 135 2020-07-20 32595297 Kweon K 2018-04-01 Soa Chongsonyon Chongsin Uihak www.ncbi.nlm.nih.gov/pubmed/32595297 Genome-Wide Analysis Reveals Four Novel Loci for Attention-Deficit Hyperactivity Disorder in Korean Youths. Attention deficit hyperactivity disorder (inattention symptoms) 27 Korean ancestry child sibling pairs NA Affymetrix [432921] 22 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST010219 Genome-wide genotyping array 27 2020-07-20 32595297 Kweon K 2018-04-01 Soa Chongsonyon Chongsin Uihak www.ncbi.nlm.nih.gov/pubmed/32595297 Genome-Wide Analysis Reveals Four Novel Loci for Attention-Deficit Hyperactivity Disorder in Korean Youths. Attention deficit hyperactivity disorder (hyperactivity-impulsivity symptoms) 27 Korean ancestry child sibling pairs NA Affymetrix [432921] 1 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST010218 Genome-wide genotyping array 27 2020-07-20 32595297 Kweon K 2018-04-01 Soa Chongsonyon Chongsin Uihak www.ncbi.nlm.nih.gov/pubmed/32595297 Genome-Wide Analysis Reveals Four Novel Loci for Attention-Deficit Hyperactivity Disorder in Korean Youths. Attention deficit hyperactivity disorder 71 Korean ancestry child cases, 64 Korean ancestry child controls NA Affymetrix [525356] 2 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST010222 Genome-wide genotyping array 135 2020-09-17 32627186 Man-Choi Ho A 2020-07-05 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/32627186 Mood Stabilizing Antiepileptic Treatment Response in Bipolar Disorder: A Genome-Wide Association Study. Response to antiepileptic mood-stabilizing treatment in bipolar disorder 199 European ancestry cases NA Illumina [7368687] (imputed) 5 response to anticonvulsant http://purl.obolibrary.org/obo/GO_0036277 GCST010579 Genome-wide genotyping array 199 2020-09-16 32581359 Saevarsdottir S 2020-06-24 Nature www.ncbi.nlm.nih.gov/pubmed/32581359 FLT3 stop mutation increases FLT3 ligand level and risk of autoimmune thyroid disease. Autoimmune thyroid disease 30,234 European ancestry cases, 724,172 European ancestry controls NA Affymetrix, Illumina [42900000] (imputed) 99 autoimmune thyroid disease http://www.ebi.ac.uk/efo/EFO_0006812 GCST010571 Genome-wide genotyping array, Genome-wide sequencing 754406 2019-03-27 30804560 Shrine N 2019-02-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30804560 New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Lung function (FVC) 321,047 European ancestry individuals 79,005 European ancestry individuals Affymetrix [19819130] (imputed) 161 vital capacity http://www.ebi.ac.uk/efo/EFO_0004312 GCST007429 Genome-wide genotyping array 321047 2019-03-27 30804560 Shrine N 2019-02-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30804560 New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. FEV1 321,047 European ancestry individuals 79,005 European ancestry individuals Affymetrix [19819130] (imputed) 206 forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0004314 GCST007432 Genome-wide genotyping array 321047 2019-03-27 30804560 Shrine N 2019-02-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30804560 New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Lung function (FEV1/FVC) 321,047 European ancestry individuals 79,005 European ancestry individuals Affymetrix [19819130] (imputed) 162 FEV/FEC ratio http://www.ebi.ac.uk/efo/EFO_0004713 GCST007431 Genome-wide genotyping array 321047 2019-03-27 30804560 Shrine N 2019-02-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30804560 New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Peak expiratory flow 321,047 European ancestry individuals 24,218 European ancestry individuals Affymetrix [19819130] (imputed) 133 peak expiratory flow http://www.ebi.ac.uk/efo/EFO_0009718 GCST007430 Genome-wide genotyping array 321047 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Matrix metalloproteinase levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 1 matrix metalloproteinase 1 measurement http://www.ebi.ac.uk/efo/EFO_0010588 GCST90000487 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Matrix metalloproteinase-10 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 1 matrix metalloproteinase 10 measurement http://www.ebi.ac.uk/efo/EFO_0010589 GCST90000488 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Neurotrophin-3 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 neurotrophin-3 measurement http://www.ebi.ac.uk/efo/EFO_0010791 GCST90000489 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Osteoprotegerin levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 osteoprotegerin measurement http://www.ebi.ac.uk/efo/EFO_0005918 GCST90000490 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Oncostatin-M levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 oncostatin-M measurement http://www.ebi.ac.uk/efo/EFO_0010792 GCST90000491 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. PD-L1 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 programmed death-ligand 1 measurement http://www.ebi.ac.uk/efo/EFO_0010793 GCST90000492 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Stem cell factor levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 stem Cell Factor measurement http://www.ebi.ac.uk/efo/EFO_0008291 GCST90000493 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Sirtuin-2 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 NAD-dependent protein deacetylase sirtuin-2 measurement http://www.ebi.ac.uk/efo/EFO_0008241 GCST90000494 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. SLAMF1 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 SLAM family member 7 measurement http://www.ebi.ac.uk/efo/EFO_0008287 GCST90000495 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Sulfotrasferase 1A1 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 sulfotrasferase 1A1 measurement http://www.ebi.ac.uk/efo/EFO_0010797 GCST90000496 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. STAM binding protein levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 STAM binding protein measurement http://www.ebi.ac.uk/efo/EFO_0010796 GCST90000497 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Transforming growth factor-alpha levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 transforming growth factor-alpha measurement http://www.ebi.ac.uk/efo/EFO_0010798 GCST90000498 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Tumor necrosis factor beta levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 3 tumor necrosis factor beta measurement http://www.ebi.ac.uk/efo/EFO_0008308 GCST90000499 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Tumor necrosis factor receptor superfamily member 9 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 tumor necrosis factor receptor superfamily member 9 measurement http://www.ebi.ac.uk/efo/EFO_0010802 GCST90000500 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Tumor necrosis factor ligand superfamily member 14 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 tumor necrosis factor ligand superfamily member 14 measurement http://www.ebi.ac.uk/efo/EFO_0010613 GCST90000501 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Tumor necrosis factor ligand superfamily member 10 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 tumor necrosis factor ligand superfamily member 10 measurement http://www.ebi.ac.uk/efo/EFO_0010800 GCST90000502 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Tumor necrosis factor ligand superfamily member 11 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 tumor necrosis factor ligand superfamily member 11 measurement http://www.ebi.ac.uk/efo/EFO_0010617 GCST90000503 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Tumor necrosis factor ligand superfamily member 12 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 1 tumor necrosis factor ligand superfamily member 12 measurement http://www.ebi.ac.uk/efo/EFO_0010801 GCST90000504 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Urokinase-type plasminogen activator levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 urokinase-type plasminogen activator measurement http://www.ebi.ac.uk/efo/EFO_0010803 GCST90000505 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Vascular endothelial growth factor A levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 vascular endothelial growth factor A measurement http://www.ebi.ac.uk/efo/EFO_0010804 GCST90000506 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. CXCL6 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 2 CXCL6 measurement http://www.ebi.ac.uk/efo/EFO_0009423 GCST90000462 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. CXCL9 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 CXCL9 measurement http://www.ebi.ac.uk/efo/EFO_0010780 GCST90000463 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. DNER levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 delta/notch like EGF Repeat Containing protein measurement http://www.ebi.ac.uk/efo/EFO_0010781 GCST90000464 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. EN-RAGE levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 advanced glycosylation end product-specific receptor ligand measurement http://www.ebi.ac.uk/efo/EFO_0010762 GCST90000465 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Fibroblast growth factor 19 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 fibroblast growth factor 19 measurement http://www.ebi.ac.uk/efo/EFO_0010782 GCST90000466 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Fibroblast growth factor 21 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 fibroblast growth factor 21 measurement http://www.ebi.ac.uk/efo/EFO_0010783 GCST90000467 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Fibroblast growth factor 23 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 fibroblast growth factor 23 measurement http://www.ebi.ac.uk/efo/EFO_0009381 GCST90000468 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Fibroblast growth factor 5 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 1 fibroblast growth factor 5 measurement http://www.ebi.ac.uk/efo/EFO_0010784 GCST90000469 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Flt3L levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 fms related receptor tyrosine kinase-3 ligand measurement http://www.ebi.ac.uk/efo/EFO_0010785 GCST90000470 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Hepatocyte growth factor levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 hepatocyte growth factor measurement http://www.ebi.ac.uk/efo/EFO_0006903 GCST90000471 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Interleukin-10 receptor B levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 1 interleukin-10 receptor B measurement http://www.ebi.ac.uk/efo/EFO_0010786 GCST90000472 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Interleukin-12 subunit B levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 2 interleukin 12 measurement http://www.ebi.ac.uk/efo/EFO_0004753 GCST90000473 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. interleukin 15 receptor subunit alpha levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 1 interleukin 15 receptor subunit alpha measurement http://www.ebi.ac.uk/efo/EFO_0008172 GCST90000474 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. interleukin-18 receptor 1 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 2 interleukin 18 receptor 1 measurement http://www.ebi.ac.uk/efo/EFO_0008178 GCST90000475 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Interleukin-10 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 interleukin 10 measurement http://www.ebi.ac.uk/efo/EFO_0004750 GCST90000476 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Interleukin-18 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 interleukin 18 measurement http://www.ebi.ac.uk/efo/EFO_0004581 GCST90000477 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Interleukin-6 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 interleukin-6 measurement http://www.ebi.ac.uk/efo/EFO_0004810 GCST90000478 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Interleukin-7 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 interleukin 7 measurement http://www.ebi.ac.uk/efo/EFO_0008189 GCST90000479 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Interleukin-8 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 interleukin 8 measurement http://www.ebi.ac.uk/efo/EFO_0008191 GCST90000480 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Transforming growth factor-beta levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 transforming growth factor beta measurement http://www.ebi.ac.uk/efo/EFO_0004818 GCST90000481 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Leukemia inhibitory factor receptor levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 leukemia inhibitory factor receptor measurement http://www.ebi.ac.uk/efo/EFO_0010788 GCST90000482 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Monocyte chemoattractant protein-1 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 monocyte chemotactic protein 1 measurement http://www.ebi.ac.uk/efo/EFO_0010596 GCST90000483 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Monocyte chemoattractant protein-2 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 monocyte chemotactic protein-2 measurement http://www.ebi.ac.uk/efo/EFO_0010789 GCST90000484 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Monocyte chemoattractant protein-3 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 monocyte chemotactic protein 3 measurement http://www.ebi.ac.uk/efo/EFO_0008235 GCST90000485 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Monocyte chemoattractant protein-4 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 2 monocyte chemotactic protein-4 measurement http://www.ebi.ac.uk/efo/EFO_0010790 GCST90000486 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. 4E-BP1 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 4E-BP1 measurement http://www.ebi.ac.uk/efo/EFO_0010760 GCST90000437 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Adenosine Deaminase levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 1 adenosine deaminase measurement http://www.ebi.ac.uk/efo/EFO_0010761 GCST90000438 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Axin-1 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 axin-1 measurement http://www.ebi.ac.uk/efo/EFO_0010763 GCST90000439 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. beta-nerve growth factor levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 beta-nerve growth factor measurement http://www.ebi.ac.uk/efo/EFO_0008035 GCST90000440 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Caspase 8 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 caspase-8 measurement http://www.ebi.ac.uk/efo/EFO_0010764 GCST90000441 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. CCL11 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 CCL11 measurement http://www.ebi.ac.uk/efo/EFO_0005188 GCST90000442 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. CCL19 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 CCL19 measurement http://www.ebi.ac.uk/efo/EFO_0009415 GCST90000443 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. CCL20 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 CCL20 measurement http://www.ebi.ac.uk/efo/EFO_0010766 GCST90000444 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. CCL23 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 1 CCL23 measurement http://www.ebi.ac.uk/efo/EFO_0009417 GCST90000445 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. CCL25 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 2 CCL25 measurement http://www.ebi.ac.uk/efo/EFO_0010768 GCST90000446 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. CCL28 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 CCL28 measurement http://www.ebi.ac.uk/efo/EFO_0010769 GCST90000447 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. CCL3 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 CCL3 measurement http://www.ebi.ac.uk/efo/EFO_0010770 GCST90000448 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. CCL4 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 CCL4 measurement http://www.ebi.ac.uk/efo/EFO_0004751 GCST90000449 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. CD244 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 CD244 measurement http://www.ebi.ac.uk/efo/EFO_0010772 GCST90000450 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. CD40 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 1 CD40 measurement http://www.ebi.ac.uk/efo/EFO_0010586 GCST90000451 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. CD5 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 CD5 measurement http://www.ebi.ac.uk/efo/EFO_0010773 GCST90000452 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. CD6 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 1 CD6 measurement http://www.ebi.ac.uk/efo/EFO_0010774 GCST90000453 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. CDCP1 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 CUB domain containing protein 1 measurement http://www.ebi.ac.uk/efo/EFO_0010776 GCST90000454 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Colony stimulating factor levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 colony stimulating factor 1 measurement http://www.ebi.ac.uk/efo/EFO_0010775 GCST90000455 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. Cystatin D levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 1 cystatin-D measurement http://www.ebi.ac.uk/efo/EFO_0008103 GCST90000456 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. CX3CL1 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 CX3CL1 measurement http://www.ebi.ac.uk/efo/EFO_0009419 GCST90000457 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. CXCL1 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 CXCL1 measurement http://www.ebi.ac.uk/efo/EFO_0010777 GCST90000458 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. CXCL10 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 CXCL10 measurement http://www.ebi.ac.uk/efo/EFO_0010778 GCST90000459 Genome-wide genotyping array 982 2020-07-24 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. CXCL11 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 0 CCL11 measurement http://www.ebi.ac.uk/efo/EFO_0005188 GCST90000460 Genome-wide genotyping array 982 2020-07-23 32641083 Hillary RF 2020-07-08 Genome Med www.ncbi.nlm.nih.gov/pubmed/32641083 Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults. CXCL5 levels 982 Scottish ancestry individuals NA Illumina [7903493] (imputed) 1 CXCL5 measurement http://www.ebi.ac.uk/efo/EFO_0009422 GCST90000461 Genome-wide genotyping array 982 2021-02-03 32641180 Steffens DC 2020-07-09 Int Psychogeriatr www.ncbi.nlm.nih.gov/pubmed/32641180 Genome-wide screen to identify genetic loci associated with cognitive decline in late-life depression. Alzheimer's disease in depression 12 European ancestry cases, 111 European ancestry controls NA Illumina [3730665] (imputed) 0 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST011070 Genome-wide genotyping array 123 2021-02-03 32641180 Steffens DC 2020-07-09 Int Psychogeriatr www.ncbi.nlm.nih.gov/pubmed/32641180 Genome-wide screen to identify genetic loci associated with cognitive decline in late-life depression. Cognitive function in depression 222 European ancestry older individuals NA Illumina [3730665] (imputed) 1 cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0008354 GCST011069 Genome-wide genotyping array 222 2021-02-03 32641180 Steffens DC 2020-07-09 Int Psychogeriatr www.ncbi.nlm.nih.gov/pubmed/32641180 Genome-wide screen to identify genetic loci associated with cognitive decline in late-life depression. Cognitive impairment in depression 31 European ancestry cases, 111 European ancestry controls NA Illumina [3730665] (imputed) 1 Cognitive impairment http://purl.obolibrary.org/obo/HP_0100543 GCST011068 Genome-wide genotyping array 142 2021-02-03 32641180 Steffens DC 2020-07-09 Int Psychogeriatr www.ncbi.nlm.nih.gov/pubmed/32641180 Genome-wide screen to identify genetic loci associated with cognitive decline in late-life depression. Cognitive decline in depression 222 European ancestry older individuals NA Illumina [3730665] (imputed) 1 cognitive decline measurement http://www.ebi.ac.uk/efo/EFO_0007710 GCST011067 Genome-wide genotyping array 222 2020-09-17 32634583 Meng Y 2020-07-04 Int J Infect Dis www.ncbi.nlm.nih.gov/pubmed/32634583 Genome-wide association study identifies TPH2 variant as a novel locus for severe CV-A6-associated hand, foot, and mouth disease in Han Chinese. CV-A6-associated hand, foot, and mouth disease (severe vs mild) 115 Han Chinese ancestry severe cases, 115 Han Chinese ancestry mild controls NA Illumina [NR] 6 hand, foot and mouth disease, illness severity status http://www.ebi.ac.uk/efo/EFO_0007294, http://www.ebi.ac.uk/efo/EFO_0007863 GCST010578 Genome-wide genotyping array 230 2020-09-21 32635940 Nudel R 2020-07-07 BMC Neurosci www.ncbi.nlm.nih.gov/pubmed/32635940 Quantitative genome-wide association analyses of receptive language in the Danish High Risk and Resilience Study. Receptive language ability 400 European ancestry children NA Illumina [299604] 3 receptive language perception http://www.ebi.ac.uk/efo/EFO_0005686 GCST010606 Genome-wide genotyping array 400 2020-09-21 32635940 Nudel R 2020-07-07 BMC Neurosci www.ncbi.nlm.nih.gov/pubmed/32635940 Quantitative genome-wide association analyses of receptive language in the Danish High Risk and Resilience Study. Parent of origin effect on receptive language ability (paternal) 400 European ancestry children NA Illumina [up to 299604] 12 receptive language perception, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0005686, http://www.ebi.ac.uk/efo/EFO_0005939 GCST010605 Genome-wide genotyping array 400 2020-09-21 32635940 Nudel R 2020-07-07 BMC Neurosci www.ncbi.nlm.nih.gov/pubmed/32635940 Quantitative genome-wide association analyses of receptive language in the Danish High Risk and Resilience Study. Parent of origin effect on receptive language ability (maternal) 400 European ancestry children NA Illumina [up to 299604] 1 receptive language perception, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0005686, http://www.ebi.ac.uk/efo/EFO_0005939 GCST010604 Genome-wide genotyping array 400 2020-09-10 32503578 Yang DW 2020-06-05 J Transl Med www.ncbi.nlm.nih.gov/pubmed/32503578 Genome-wide association study identifies genetic susceptibility loci and pathways of radiation-induced acute oral mucositis. Response to radiotherapy in nasopharyngeal carcinoma (acute oral mucositis) 349 East Asian ancestry cases, 1,118 East Asian ancestry treated controls NA Illumina [3968928] (imputed) 5 oral mucositis, response to radiation http://www.ebi.ac.uk/efo/EFO_1001904, http://purl.obolibrary.org/obo/GO_0009314 GCST010511 Genome-wide genotyping array 1467 2020-09-21 32649856 Rodriguez BAT 2020-07-04 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32649856 A Platelet Function Modulator of Thrombin Activation Is Causally Linked to Cardiovascular Disease and Affects PAR4 Receptor Signaling. Thrombin-induced platelet aggregation 1,184 European ancestry individuals NA Affymetrix [7751469] (imputed) 1 platelet aggregation http://purl.obolibrary.org/obo/GO_0070527 GCST010601 Genome-wide genotyping array 1184 2020-07-28 29871690 Bensen JT 2018-06-05 Breast Cancer Res www.ncbi.nlm.nih.gov/pubmed/29871690 A survey of microRNA single nucleotide polymorphisms identifies novel breast cancer susceptibility loci in a case-control, population-based study of African-American women. Breast cancer 3,663 African American cases, 4,687 African American controls NA Illumina [300008] 1 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST010347 Exome genotyping array [Exome array] 8350 2019-08-28 30972912 Wei L 2019-04-10 J Viral Hepat www.ncbi.nlm.nih.gov/pubmed/30972912 Genetic variation in FCER1A predicts peginterferon alfa-2a-induced hepatitis B surface antigen clearance in East Asian patients with chronic hepatitis B. Peginterferon alfa-2a treatment response in chronic hepatitis B infection up to 1,108 East Asian cases, up to 465 European ancestry cases, up to 63 cases NA Illumina [> 750000] 27 response to peginterferon alfa-2a http://www.ebi.ac.uk/efo/EFO_0010103 GCST008514 Genome-wide genotyping array 1636 2021-02-03 32632093 Guo Y 2020-07-06 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32632093 A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine. Migraine and/or diastolic blood pressure 757,601 European ancestry individuals with blood pressure measurements, 59,674 European ancestry migraine cases, 316,078 European ancestry controls NA NR [up to 7000000] 20 diastolic blood pressure, migraine disorder http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0003821 GCST011064 Genome-wide genotyping array 1133353 2021-02-03 32632093 Guo Y 2020-07-06 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32632093 A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine. Migraine and/or systolic blood pressure 757,601 European ancestry individuals with blood pressure measurements, 59,674 European ancestry migraine cases, 316,078 European ancestry controls NA NR [up to 7000000] 16 systolic blood pressure, migraine disorder http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0003821 GCST011063 Genome-wide genotyping array 1133353 2021-02-03 32632093 Guo Y 2020-07-06 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32632093 A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine. Migraine and/or pulse pressure 757,601 European ancestry individuals with blood pressure measurements, 59,674 European ancestry migraine cases, 316,078 European ancestry controls NA NR [up to 7000000] 20 pulse pressure measurement, migraine disorder http://www.ebi.ac.uk/efo/EFO_0005763, http://www.ebi.ac.uk/efo/EFO_0003821 GCST011062 Genome-wide genotyping array 1133353 2021-02-03 32632093 Guo Y 2020-07-06 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32632093 A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine. Migraine with aura and/or diastolic blood pressure 757,601 European ancestry individuals with blood pressure measurements, up to 59,674 European ancestry migraine cases, 316,078 European ancestry controls NA NR [up to 7000000] 2 diastolic blood pressure, migraine with aura http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0005295 GCST011061 Genome-wide genotyping array 1133353 2021-02-03 32632093 Guo Y 2020-07-06 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32632093 A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine. Migraine with aura and/or systolic blood pressure 757,601 European ancestry individuals with blood pressure measurements, up to 59,674 European ancestry migraine cases, 316,078 European ancestry controls NA NR [up to 7000000] 2 systolic blood pressure, migraine with aura http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0005295 GCST011060 Genome-wide genotyping array 1133353 2021-02-03 32632093 Guo Y 2020-07-06 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32632093 A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine. Migraine with aura and/or pulse pressure 757,601 European ancestry individuals with blood pressure measurements, up to 59,674 European ancestry migraine cases, 316,078 European ancestry controls NA NR [up to 7000000] 2 pulse pressure measurement, migraine with aura http://www.ebi.ac.uk/efo/EFO_0005763, http://www.ebi.ac.uk/efo/EFO_0005295 GCST011059 Genome-wide genotyping array 1133353 2021-02-03 32632093 Guo Y 2020-07-06 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32632093 A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine. Migraine without aura and/or diastolic blood pressure 757,601 European ancestry individuals with blood pressure measurements, up to 59,674 European ancestry migraine cases, 316,078 European ancestry controls NA NR [up to 7000000] 5 diastolic blood pressure, migraine without aura http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0005296 GCST011058 Genome-wide genotyping array 1133353 2021-02-03 32632093 Guo Y 2020-07-06 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32632093 A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine. Migraine without aura and/or systolic blood pressure 757,601 European ancestry individuals with blood pressure measurements, up to 59,674 European ancestry migraine cases, 316,078 European ancestry controls NA NR [up to 7000000] 3 systolic blood pressure, migraine without aura http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0005296 GCST011057 Genome-wide genotyping array 1133353 2021-02-03 32632093 Guo Y 2020-07-06 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32632093 A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine. Migraine without aura and/or pulse pressure 757,601 European ancestry individuals with blood pressure measurements, up to 59,674 European ancestry migraine cases, 316,078 European ancestry controls NA NR [up to 7000000] 6 pulse pressure measurement, migraine without aura http://www.ebi.ac.uk/efo/EFO_0005763, http://www.ebi.ac.uk/efo/EFO_0005296 GCST011056 Genome-wide genotyping array 1133353 2020-09-04 32492107 Huang XF 2020-06-01 Invest Ophthalmol Vis Sci www.ncbi.nlm.nih.gov/pubmed/32492107 Genomewide Association Study of Acute Anterior Uveitis Identifies New Susceptibility Loci. Acute anterior uveitis in ankylosing spondylitis 2,752 European ancestry cases, 3,836 European ancestry controls NA Illumina [7436415] (imputed) 12 anterior uveitis http://www.ebi.ac.uk/efo/EFO_1000811 GCST010481 Genome-wide genotyping array 6588 2020-09-16 32573913 Sherva R 2020-06-23 Alzheimers Dement www.ncbi.nlm.nih.gov/pubmed/32573913 Genome-wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways. Rate of cognitive decline in Alzheimer's disease 3,946 European ancestry cases NA NR [NR] (imputed) 184 cognitive decline measurement http://www.ebi.ac.uk/efo/EFO_0007710 GCST010567 Genome-wide genotyping array 3946 2020-09-10 32488134 Auckland K 2020-06-02 Sci Rep www.ncbi.nlm.nih.gov/pubmed/32488134 The Human Leukocyte Antigen Locus and Rheumatic Heart Disease Susceptibility in South Asians and Europeans. Rheumatic heart disease 510 Northern Indian cases, 344 Northern Indian controls, 162 Fijian Indian cases, 147 Fijian Indian controls 150 European ancestry cases, 1,309 European ancestry controls Illumina [6925553] (imputed) 3 rheumatic heart disease http://www.ebi.ac.uk/efo/EFO_1001161 GCST010509 Genome-wide genotyping array 1163 2021-03-25 32701512 Cairns J 2020-07-23 JCI Insight www.ncbi.nlm.nih.gov/pubmed/32701512 Pharmacogenomics of aromatase inhibitors in postmenopausal breast cancer and additional mechanisms of anastrozole action. Estrogen level change in anastrozole-treated breast cancer 624 individuals NA Illumina [up to 8000000] (imputed) 5 estrogen measurement, response to aromatase inhibitor http://www.ebi.ac.uk/efo/EFO_0011007, http://purl.obolibrary.org/obo/GO_0061477 GCST011407 Genome-wide genotyping array 624 2020-06-25 25555482 Gelernter J 2014-09-16 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/25555482 Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans. Nicotine dependence symptom count 3,529 African American individuals, 4,117 European American individuals NA Illumina [up to 11995908] (imputed) 206 nicotine dependence symptom count http://www.ebi.ac.uk/efo/EFO_0009262 GCST010105 Genome-wide genotyping array 7646 2019-04-10 30804558 Grove J 2019-02-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30804558 Identification of common genetic risk variants for autism spectrum disorder. Autism spectrum disorder 18,381 European ancestry cases, 27,969 European ancestry controls 2,119 European ancestry cases, 142,379 European ancestry controls Illumina [9112387] (imputed) 46 autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0003756 GCST007556 Genome-wide genotyping array 46350 2019-04-10 30804558 Grove J 2019-02-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30804558 Identification of common genetic risk variants for autism spectrum disorder. Autism and major depressive disorder (MTAG) 18,381 European ancestry autism cases, 27,969 European ancestry controls, 111,902 major depression cases, 312,113 controls NA Illumina [NR] (imputed) 8 unipolar depression, autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0003756 GCST007553 Genome-wide genotyping array 470365 2019-04-10 30804558 Grove J 2019-02-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30804558 Identification of common genetic risk variants for autism spectrum disorder. Autism and schizophrenia (MTAG) 18,381 European ancestry autism cases, 27,969 European ancestry controls, 34,129 schizophrenia cases, 45,512 controls NA Illumina [NR] (imputed) 4 schizophrenia, autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0003756 GCST007555 Genome-wide genotyping array 125991 2019-04-10 30804558 Grove J 2019-02-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30804558 Identification of common genetic risk variants for autism spectrum disorder. Autism and educational attainment (MTAG) 18,381 European ancestry autism cases, 27,969 European ancestry controls, 328,917 individuals with educational attainment data NA Illumina [NR] (imputed) 4 autism spectrum disorder, self reported educational attainment http://www.ebi.ac.uk/efo/EFO_0003756, http://www.ebi.ac.uk/efo/EFO_0004784 GCST007554 Genome-wide genotyping array 375267 2019-10-03 30806694 Walker GJ 2019-02-01 JAMA www.ncbi.nlm.nih.gov/pubmed/30806694 Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease. Thiopurine-induced myelosuppression in inflammatory bowel disease 311 European ancestry cases, 608 European ancestry controls NA NR [6272335] (imputed) 1 myelosuppression, response to thiopurine http://www.ebi.ac.uk/efo/EFO_0007053, http://www.ebi.ac.uk/efo/EFO_0006317 GCST008801 Genome-wide genotyping array 919 2019-09-02 30801552 Oetting WS 2019-02-19 Transplantation www.ncbi.nlm.nih.gov/pubmed/30801552 Genetic Variants Associated with Immunosuppressant Pharmacokinetics and Adverse Effects in the DeKAF Genomics Genome Wide Association Studies. Tacrolimus trough concentration in kidney transplant patients 1,363 European ancestry individuals, 299 African American individuals 609 European ancestry individuals, 171 African American individuals Affymetrix [~ 40000000] (imputed) 4 tacrolimus measurement http://www.ebi.ac.uk/efo/EFO_0008458 GCST008577 Genome-wide genotyping array 1662 2019-09-02 30801552 Oetting WS 2019-02-19 Transplantation www.ncbi.nlm.nih.gov/pubmed/30801552 Genetic Variants Associated with Immunosuppressant Pharmacokinetics and Adverse Effects in the DeKAF Genomics Genome Wide Association Studies. Nephrotoxicity in tacrolimus-treated kidney transplant patients (time to event) 1,352 European ancestry individuals 609 European ancestry individuals Affymetrix [~ 40000000] (imputed) 0 renal system measurement, Acute kidney injury, response to tacrolimus http://www.ebi.ac.uk/efo/EFO_0004742, http://purl.obolibrary.org/obo/HP_0001919, http://www.ebi.ac.uk/efo/EFO_0010052 GCST008582 Genome-wide genotyping array 1352 2019-09-02 30801552 Oetting WS 2019-02-19 Transplantation www.ncbi.nlm.nih.gov/pubmed/30801552 Genetic Variants Associated with Immunosuppressant Pharmacokinetics and Adverse Effects in the DeKAF Genomics Genome Wide Association Studies. Nephrotoxicity in cyclosporine-treated kidney transplant patients (time to event) 475 European ancestry individuals 63 European ancestry individuals Affymetrix [~ 40000000] (imputed) 0 renal system measurement, response to cyclosporine, Acute kidney injury http://www.ebi.ac.uk/efo/EFO_0004742, http://www.ebi.ac.uk/efo/EFO_0010053, http://purl.obolibrary.org/obo/HP_0001919 GCST008581 Genome-wide genotyping array 475 2019-09-02 30801552 Oetting WS 2019-02-19 Transplantation www.ncbi.nlm.nih.gov/pubmed/30801552 Genetic Variants Associated with Immunosuppressant Pharmacokinetics and Adverse Effects in the DeKAF Genomics Genome Wide Association Studies. Anemia in mycophenolic acid treated kidney transplant patients (time to event) 1,785 European ancestry individuals 438 European ancestry individuals Affymetrix [~ 40000000] (imputed) 0 anemia (phenotype), response to mycophenolic acid http://www.ebi.ac.uk/efo/EFO_0004272, http://www.ebi.ac.uk/efo/EFO_0010054 GCST008580 Genome-wide genotyping array 1785 2019-09-02 30801552 Oetting WS 2019-02-19 Transplantation www.ncbi.nlm.nih.gov/pubmed/30801552 Genetic Variants Associated with Immunosuppressant Pharmacokinetics and Adverse Effects in the DeKAF Genomics Genome Wide Association Studies. Leukopenia in mycophenolic acid treated kidney transplant patients (time to event) 1,785 European ancestry individuals, 338 African American individuals 657 European ancestry individuals, 171 African American individuals Affymetrix [~ 40000000] (imputed) 0 leukopenia, response to mycophenolic acid http://www.ebi.ac.uk/efo/EFO_0004233, http://www.ebi.ac.uk/efo/EFO_0010054 GCST008579 Genome-wide genotyping array 2123 2019-09-02 30801552 Oetting WS 2019-02-19 Transplantation www.ncbi.nlm.nih.gov/pubmed/30801552 Genetic Variants Associated with Immunosuppressant Pharmacokinetics and Adverse Effects in the DeKAF Genomics Genome Wide Association Studies. New onset diabetes in calcineurin inhibitor treated kidney transplant patients (time to event) 1,235 European ancestry individuals, 256 African American individuals 487 European ancestry individuals, 94 African American individuals Affymetrix [~ 40000000] (imputed) 0 response to calcineurin inhibitor, diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0010055, http://www.ebi.ac.uk/efo/EFO_0000400 GCST008578 Genome-wide genotyping array 1491 2019-03-27 28864454 Lacson JCA 2017-09-01 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/28864454 Genome-Wide Testing of Exonic Variants and Breast Cancer Risk in the California Teachers Study. Breast cancer (estrogen-receptor positive) 1,325 cases, 1,310 controls NA Illumina [129771] 2 estrogen-receptor positive breast cancer http://www.ebi.ac.uk/efo/EFO_1000649 GCST007415 Exome genotyping array [Exome array] 2635 2019-03-27 28864454 Lacson JCA 2017-09-01 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/28864454 Genome-Wide Testing of Exonic Variants and Breast Cancer Risk in the California Teachers Study. Breast cancer (estrogen-receptor negative) 212 cases, 1,310 controls NA Illumina [129771] 0 estrogen-receptor negative breast cancer http://www.ebi.ac.uk/efo/EFO_1000650 GCST007416 Exome genotyping array [Exome array] 1522 2019-03-27 28864454 Lacson JCA 2017-09-01 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/28864454 Genome-Wide Testing of Exonic Variants and Breast Cancer Risk in the California Teachers Study. Breast cancer (progesterone-receptor positive) 1,049 cases, 1,310 controls NA Illumina [129771] 1 progesterone-receptor negative breast cancer http://www.ebi.ac.uk/efo/EFO_0009781 GCST007420 Exome genotyping array [Exome array] 2359 2019-03-27 28864454 Lacson JCA 2017-09-01 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/28864454 Genome-Wide Testing of Exonic Variants and Breast Cancer Risk in the California Teachers Study. Breast cancer (progesterone-receptor negative) 419 cases, 1,310 controls NA Illumina [129771] 0 progesterone-receptor negative breast cancer http://www.ebi.ac.uk/efo/EFO_0009781 GCST007417 Exome genotyping array [Exome array] 1729 2019-03-27 28864454 Lacson JCA 2017-09-01 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/28864454 Genome-Wide Testing of Exonic Variants and Breast Cancer Risk in the California Teachers Study. Breast cancer (HER2 positive) 194 cases, 1,310 controls NA Illumina [129771] 0 HER2 Positive Breast Carcinoma http://www.ebi.ac.uk/efo/EFO_1000294 GCST007419 Exome genotyping array [Exome array] 1504 2019-03-27 28864454 Lacson JCA 2017-09-01 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/28864454 Genome-Wide Testing of Exonic Variants and Breast Cancer Risk in the California Teachers Study. Breast cancer (HER2 negative) 932 cases, 1,310 controls NA Illumina [129771] 0 HER2 negative breast carcinoma http://www.ebi.ac.uk/efo/EFO_0009780 GCST007418 Exome genotyping array [Exome array] 2242 2019-03-27 28864454 Lacson JCA 2017-09-01 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/28864454 Genome-Wide Testing of Exonic Variants and Breast Cancer Risk in the California Teachers Study. Breast cancer 1,704 cases, 1,310 controls NA Illumina [129771] 0 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST007414 Exome genotyping array [Exome array] 3014 2019-02-14 30201983 Tulstrup M 2018-09-10 Leukemia www.ncbi.nlm.nih.gov/pubmed/30201983 NT5C2 germline variants alter thiopurine metabolism and are associated with acquired NT5C2 relapse mutations in childhood acute lymphoblastic leukaemia. Erythrocyte methylated 6-mercaptopurine metabolite concentration in 6-mercaptopurine-treated acute lymphoblastic leukaemia up to 454 European ancestry individuals NA Illumina [NR] 1 thiopurine metabolite measurement, response to mercaptopurine http://www.ebi.ac.uk/efo/EFO_0009693, http://www.ebi.ac.uk/efo/EFO_0007853 GCST007149 Genome-wide genotyping array 454 2019-02-14 30201983 Tulstrup M 2018-09-10 Leukemia www.ncbi.nlm.nih.gov/pubmed/30201983 NT5C2 germline variants alter thiopurine metabolism and are associated with acquired NT5C2 relapse mutations in childhood acute lymphoblastic leukaemia. DNA-incorporated thioguanine levels in 6-mercaptopurine-treated acute lymphoblastic leukaemia 443 European ancestry individuals NA Illumina [NR] 1 thiopurine metabolite measurement, response to mercaptopurine http://www.ebi.ac.uk/efo/EFO_0009693, http://www.ebi.ac.uk/efo/EFO_0007853 GCST007150 Genome-wide genotyping array 443 2019-02-14 30201983 Tulstrup M 2018-09-10 Leukemia www.ncbi.nlm.nih.gov/pubmed/30201983 NT5C2 germline variants alter thiopurine metabolism and are associated with acquired NT5C2 relapse mutations in childhood acute lymphoblastic leukaemia. DNA-incorporated thioguanine to erythrocyte thioguanine ratio in 6-mercaptopurine-treated acute lymphoblastic leukaemia up to 443 European ancestry individuals up to 136 European ancestry individuals Illumina [NR] 0 thiopurine metabolite measurement, response to mercaptopurine http://www.ebi.ac.uk/efo/EFO_0009693, http://www.ebi.ac.uk/efo/EFO_0007853 GCST007151 Genome-wide genotyping array 443 2019-02-14 30201983 Tulstrup M 2018-09-10 Leukemia www.ncbi.nlm.nih.gov/pubmed/30201983 NT5C2 germline variants alter thiopurine metabolism and are associated with acquired NT5C2 relapse mutations in childhood acute lymphoblastic leukaemia. Erythrocyte thioguanine concentration in 6-mercaptopurine-treated acute lymphoblastic leukaemia 452 European ancestry individuals NA Illumina [NR] 1 thiopurine metabolite measurement, response to mercaptopurine http://www.ebi.ac.uk/efo/EFO_0009693, http://www.ebi.ac.uk/efo/EFO_0007853 GCST007148 Genome-wide genotyping array 452 2019-04-09 30808845 Thio CHL 2019-02-26 Am J Nephrol www.ncbi.nlm.nih.gov/pubmed/30808845 Genome-Wide Association Scan of Serum Urea in European Populations Identifies Two Novel Loci. Serum urea levels 13,312 European ancestry individuals 7,379 European ancestry individuals Illumina [1990000] (imputed) 6 serum urea measurement http://www.ebi.ac.uk/efo/EFO_0009795 GCST007536 Genome-wide genotyping array 13312 2020-07-21 32193296 Grasby KL 2020-03-01 Science www.ncbi.nlm.nih.gov/pubmed/32193296 The genetic architecture of the human cerebral cortex. Cortical thickness 33,992 European ancestry individuals 14,727 European ancestry individuals, 2,943 individuals Affymetrix, Illumina [NR] 26 cortical thickness http://www.ebi.ac.uk/efo/EFO_0004840 GCST010281 Genome-wide genotyping array 33992 2020-07-21 32193296 Grasby KL 2020-03-01 Science www.ncbi.nlm.nih.gov/pubmed/32193296 The genetic architecture of the human cerebral cortex. Cortical surface area 33,992 European ancestry individuals 14,727 European ancestry individuals, 2,943 individuals Affymetrix, Illumina [NR] 261 cortical surface area measurement http://www.ebi.ac.uk/efo/EFO_0010736 GCST010282 Genome-wide genotyping array 33992 2019-05-01 30804561 Sakornsakolpat P 2019-02-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30804561 Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations. Chronic obstructive pulmonary disease 35,735 cases, 222,076 controls NA Affymetrix, Illumina [6224355] (imputed) 124 chronic obstructive pulmonary disease http://www.ebi.ac.uk/efo/EFO_0000341 GCST007692 Genome-wide genotyping array 257811 2020-04-16 31407531 Do AN 2019-08-13 Mol Genet Genomic Med www.ncbi.nlm.nih.gov/pubmed/31407531 Genome-wide meta-analysis of SNP and antihypertensive medication interactions on left ventricular traits in African Americans. Left ventricular mass x antihypertensive treatment interaction up to 2,068 African American individuals up to 613 European ancestry individuals Affymetrix, Illumina [up to 2191657] (imputed) 3 response to antihypertensive drug, left ventricular mass http://www.ebi.ac.uk/efo/EFO_0005405, http://www.ebi.ac.uk/efo/EFO_0009289 GCST009835 Genome-wide genotyping array 2068 2020-04-16 31407531 Do AN 2019-08-13 Mol Genet Genomic Med www.ncbi.nlm.nih.gov/pubmed/31407531 Genome-wide meta-analysis of SNP and antihypertensive medication interactions on left ventricular traits in African Americans. Relative wall thickness x antihypertensive treatment interaction up to 2,068 African American individuals up to 613 European ancestry individuals Affymetrix, Illumina [up to 2191661] (imputed) 2 response to antihypertensive drug, heart relative wall thickness http://www.ebi.ac.uk/efo/EFO_0005405, http://www.ebi.ac.uk/efo/EFO_0009286 GCST009836 Genome-wide genotyping array 2068 2020-08-25 32378780 Park B 2020-05-07 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/32378780 Genome-Wide Association Study of Genetic Variants Related to Anthracycline-Induced Cardiotoxicity in Early Breast Cancer. Anthracycline-induced cardiotoxicity in early breast cancer 42 Korean ancestry cases, 215 Korean ancestry controls NA NR [346946] 7 cardiotoxicity, response to anthracycline-based chemotherapy http://www.ebi.ac.uk/efo/EFO_1001482, http://www.ebi.ac.uk/efo/EFO_0005257 GCST010456 Genome-wide genotyping array 257 2019-06-24 30678657 Westphal S 2019-01-24 BMC Cardiovasc Disord www.ncbi.nlm.nih.gov/pubmed/30678657 Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery - a sub-analysis of the RIPHeart-Study. Postoperative myocardial infarction after cardiac surgery 87 cases, 939 controls NA Illumina [9007469] (imputed) 2 response to surgery, post-operative myocardial infarction http://www.ebi.ac.uk/efo/EFO_0009951, http://www.ebi.ac.uk/efo/EFO_0009953 GCST007976 Genome-wide genotyping array 1026 2019-06-24 30678657 Westphal S 2019-01-24 BMC Cardiovasc Disord www.ncbi.nlm.nih.gov/pubmed/30678657 Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery - a sub-analysis of the RIPHeart-Study. Postoperative stroke after cardiac surgery 17 cases, 1,089 controls NA Illumina [9007469] (imputed) 4 post-operative stroke, response to surgery http://www.ebi.ac.uk/efo/EFO_0009956, http://www.ebi.ac.uk/efo/EFO_0009951 GCST007977 Genome-wide genotyping array 1106 2019-06-24 30678657 Westphal S 2019-01-24 BMC Cardiovasc Disord www.ncbi.nlm.nih.gov/pubmed/30678657 Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery - a sub-analysis of the RIPHeart-Study. Postoperative acute renal failure after cardiac surgery 52 cases, 1,020 controls NA Illumina [9007469] (imputed) 4 post-operative acute kidney injury, response to surgery http://www.ebi.ac.uk/efo/EFO_0009955, http://www.ebi.ac.uk/efo/EFO_0009951 GCST007979 Genome-wide genotyping array 1072 2019-06-24 30678657 Westphal S 2019-01-24 BMC Cardiovasc Disord www.ncbi.nlm.nih.gov/pubmed/30678657 Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery - a sub-analysis of the RIPHeart-Study. Postoperative atrial fibrillation after cardiac surgery 242 cases, 640 controls NA Illumina [9007469] (imputed) 4 post-operative atrial fibrillation, response to surgery http://www.ebi.ac.uk/efo/EFO_0009952, http://www.ebi.ac.uk/efo/EFO_0009951 GCST007978 Genome-wide genotyping array 882 2019-06-24 30678657 Westphal S 2019-01-24 BMC Cardiovasc Disord www.ncbi.nlm.nih.gov/pubmed/30678657 Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery - a sub-analysis of the RIPHeart-Study. Postoperative delirium after cardiac surgery 148 cases, 819 controls NA Illumina [9007469] (imputed) 2 response to surgery, post-operative delirium http://www.ebi.ac.uk/efo/EFO_0009951, http://www.ebi.ac.uk/efo/EFO_0009954 GCST007980 Genome-wide genotyping array 967 2019-06-24 30678657 Westphal S 2019-01-24 BMC Cardiovasc Disord www.ncbi.nlm.nih.gov/pubmed/30678657 Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery - a sub-analysis of the RIPHeart-Study. Postoperative complication after cardiac surgery Up to 1,163 individuals NA Illumina [9007469] (imputed) 3 response to surgery, post-operative sign or symptom http://www.ebi.ac.uk/efo/EFO_0009951, http://www.ebi.ac.uk/efo/EFO_0005323 GCST007981 Genome-wide genotyping array 1163 2019-04-18 30661239 Nicoletti P 2019-01-19 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/30661239 Drug-induced injury due to flucloxacillin: relevance of multiple HLA alleles. Drug-induced liver injury (flucloxacillin) 197 European ancestry cases, 6,835 European ancestry controls NA Illumina [NR] (imputed) 11 drug-induced liver injury http://www.ebi.ac.uk/efo/EFO_0004228 GCST007606 Genome-wide genotyping array 7032 2019-04-18 30661239 Nicoletti P 2019-01-19 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/30661239 Drug-induced injury due to flucloxacillin: relevance of multiple HLA alleles. Drug-induced liver injury (isoxazolyl penicillins) 6 European ancestry cases, 10,588 European ancestry controls NA Illumina [NR] (imputed) 0 drug-induced liver injury http://www.ebi.ac.uk/efo/EFO_0004228 GCST007608 Genome-wide genotyping array 10594 2019-04-18 30661239 Nicoletti P 2019-01-19 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/30661239 Drug-induced injury due to flucloxacillin: relevance of multiple HLA alleles. Drug-induced liver injury (amoxicillin) 15 European ancestry cases, 10,588 European ancestry controls NA Illumina [NR] (imputed) 0 drug-induced liver injury http://www.ebi.ac.uk/efo/EFO_0004228 GCST007607 Genome-wide genotyping array 10603 2019-03-28 30643255 Kristjansson RP 2019-01-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30643255 A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis. Chronic rhinosinusitis 251 European ancestry whole-genome sequenced cases, 5,357 European ancestry cases, 13,957 European ancestry whole-genome sequenced controls, 746,129 European ancestry controls NA Affymetrix, Illumina [up to 37123566] (imputed) 4 chronic rhinosinusitis http://www.ebi.ac.uk/efo/EFO_1000024 GCST007444 Genome-wide genotyping array, Genome-wide sequencing 765694 2019-03-28 30643255 Kristjansson RP 2019-01-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30643255 A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis. Nasal polyps 86 European ancestry whole-genome sequenced cases, 4,280 European ancestry cases, 13,941 European ancestry whole-genome sequenced controls, 700,740 European ancestry controls NA Affymetrix, Illumina [up to 37123566] (imputed) 18 Nasal Cavity Polyp http://www.ebi.ac.uk/efo/EFO_1000391 GCST007443 Genome-wide genotyping array, Genome-wide sequencing 719047 2020-09-15 32580138 Shi XY 2020-06-21 EBioMedicine www.ncbi.nlm.nih.gov/pubmed/32580138 Identification of susceptibility variants to benign childhood epilepsy with centro-temporal spikes (BECTS) in Chinese Han population. Benign childhood epilepsy with centro-temporal spikes 1,738 Han Chinese ancestry cases, 6,592 Han Chinese ancestry controls NA Illumina [5352724] (imputed) 12 Rolandic epilepsy http://www.orpha.net/ORDO/Orphanet_1945 GCST010566 Genome-wide genotyping array 8330 2020-09-17 32572135 Zhao Y 2020-06-22 Sci Rep www.ncbi.nlm.nih.gov/pubmed/32572135 Four Loci Are Associated with Cardiorespiratory Fitness and Endurance Performance in Young Chinese Females. Cardiorespiratory fitness (800m run time) 762 Han Chinese ancestry individuals NA Affymetrix, Illumina [5129327] (imputed) 8 exercise test http://www.ebi.ac.uk/efo/EFO_0004328 GCST010573 Genome-wide genotyping array 762 2020-11-26 32589924 Bi W 2020-06-23 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32589924 A Fast and Accurate Method for Genome-Wide Time-to-Event Data Analysis and Its Application to UK Biobank. Essential hypertension (time to event) 76,566 British ancestry cases, 206,305 British ancestry controls NA NR [~ 24000000] (imputed) 34 age at diagnosis, primary hypertension http://www.ebi.ac.uk/efo/EFO_0004918, http://www.ebi.ac.uk/efo/EFO_1002032 GCST010774 Genome-wide genotyping array 282871 2020-11-26 32589924 Bi W 2020-06-23 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32589924 A Fast and Accurate Method for Genome-Wide Time-to-Event Data Analysis and Its Application to UK Biobank. Abdominal hernia (time to event) 45,957 British ancestry cases, 236,914 British ancestry controls NA NR [~ 24000000] (imputed) 0 age at diagnosis, Hernia of the abdominal wall http://www.ebi.ac.uk/efo/EFO_0004918, http://purl.obolibrary.org/obo/HP_0004299 GCST010773 Genome-wide genotyping array 282871 2020-11-26 32589924 Bi W 2020-06-23 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32589924 A Fast and Accurate Method for Genome-Wide Time-to-Event Data Analysis and Its Application to UK Biobank. Hyperlipidemia (time to event) 35,623 British ancestry cases, 247,248 British ancestry controls NA NR [~ 24000000] (imputed) 2 age at diagnosis, hyperlipidemia http://www.ebi.ac.uk/efo/EFO_0004918, http://www.ebi.ac.uk/efo/EFO_0003774 GCST010772 Genome-wide genotyping array 282871 2020-11-26 32589924 Bi W 2020-06-23 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32589924 A Fast and Accurate Method for Genome-Wide Time-to-Event Data Analysis and Its Application to UK Biobank. Osteoarthrosis (time to event) 29,071 British ancestry cases, 253,800 British ancestry controls NA NR [~ 24000000] (imputed) 5 age at diagnosis, osteoarthritis http://www.ebi.ac.uk/efo/EFO_0004918, http://www.ebi.ac.uk/efo/EFO_0002506 GCST010771 Genome-wide genotyping array 282871 2020-11-26 32589924 Bi W 2020-06-23 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32589924 A Fast and Accurate Method for Genome-Wide Time-to-Event Data Analysis and Its Application to UK Biobank. Cardiac dysrhythmias (time to event) 25,585 British ancestry cases, 257,286 British ancestry controls NA NR [~ 24000000] (imputed) 1 age at diagnosis, cardiac arrhythmia http://www.ebi.ac.uk/efo/EFO_0004918, http://www.ebi.ac.uk/efo/EFO_0004269 GCST010770 Genome-wide genotyping array 282871 2020-11-26 32589924 Bi W 2020-06-23 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32589924 A Fast and Accurate Method for Genome-Wide Time-to-Event Data Analysis and Its Application to UK Biobank. Asthma (time to event) 25,240 British ancestry cases, 257,631 British ancestry controls NA NR [~ 24000000] (imputed) 3 age at diagnosis, asthma http://www.ebi.ac.uk/efo/EFO_0004918, http://www.ebi.ac.uk/efo/EFO_0000270 GCST010769 Genome-wide genotyping array 282871 2020-11-26 32589924 Bi W 2020-06-23 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32589924 A Fast and Accurate Method for Genome-Wide Time-to-Event Data Analysis and Its Application to UK Biobank. Cataract (time to event) 22,635 British ancestry cases, 260,236 British ancestry controls NA NR [~ 24000000] (imputed) 2 cataract, age at diagnosis http://www.ebi.ac.uk/efo/EFO_0001059, http://www.ebi.ac.uk/efo/EFO_0004918 GCST010768 Genome-wide genotyping array 282871 2020-11-26 32589924 Bi W 2020-06-23 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32589924 A Fast and Accurate Method for Genome-Wide Time-to-Event Data Analysis and Its Application to UK Biobank. Coronary atherosclerosis (time to event) 19,079 British ancestry cases, 263,792 British ancestry controls NA NR [~ 24000000] (imputed) 5 age at diagnosis, coronary atherosclerosis measurement http://www.ebi.ac.uk/efo/EFO_0004918, http://www.ebi.ac.uk/efo/EFO_0007938 GCST010767 Genome-wide genotyping array 282871 2020-11-26 32589924 Bi W 2020-06-23 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32589924 A Fast and Accurate Method for Genome-Wide Time-to-Event Data Analysis and Its Application to UK Biobank. Type 2 diabetes (time to event) 18,557 British ancestry cases, 264,314 British ancestry controls NA NR [~ 24000000] (imputed) 3 age at diagnosis, type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0004918, http://www.ebi.ac.uk/efo/EFO_0001360 GCST010766 Genome-wide genotyping array 282871 2020-11-26 32589924 Bi W 2020-06-23 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32589924 A Fast and Accurate Method for Genome-Wide Time-to-Event Data Analysis and Its Application to UK Biobank. Parkinson's disease (time to event) 1,345 British ancestry cases, 281,526 British ancestry controls NA NR [~ 24000000] (imputed) 0 Parkinson's disease, age at diagnosis http://www.ebi.ac.uk/efo/EFO_0002508, http://www.ebi.ac.uk/efo/EFO_0004918 GCST010765 Genome-wide genotyping array 282871 2020-11-26 32589924 Bi W 2020-06-23 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32589924 A Fast and Accurate Method for Genome-Wide Time-to-Event Data Analysis and Its Application to UK Biobank. Alzheimer's disease (time to event) 641 British ancestry cases, 282,230 British ancestry controls NA NR [~ 24000000] (imputed) 0 Alzheimer's disease, age at diagnosis http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0004918 GCST010764 Genome-wide genotyping array 282871 2020-11-26 32589924 Bi W 2020-06-23 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32589924 A Fast and Accurate Method for Genome-Wide Time-to-Event Data Analysis and Its Application to UK Biobank. Schizophrenia (time to event) 551 British ancestry cases, 282,320 British ancestry controls NA NR [~ 24000000] (imputed) 0 age at diagnosis, schizophrenia http://www.ebi.ac.uk/efo/EFO_0004918, http://www.ebi.ac.uk/efo/EFO_0000692 GCST010763 Genome-wide genotyping array 282871 2020-06-04 32296059 Han Y 2020-04-15 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32296059 Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma. Asthma 84,492 European ancestry cases, 2,149 African American cases, 606 Hispanic cases, 1,239 Japanese ancestry cases, 437,036 European ancestry controls, 6,055 African American controls, 792 Hispanic controls, 3,976 Japanese ancestry controls NR NR [> 9500000] (imputed) 167 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST010043 Genome-wide genotyping array 536345 2020-06-04 32296059 Han Y 2020-04-15 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32296059 Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma. Asthma 64,538 European ancestry cases, 239,321 European ancestry controls NR NR [9572556] (imputed) 145 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST010042 Genome-wide genotyping array 303859 2020-07-07 32528159 Choquet H 2020-06-11 Commun Biol www.ncbi.nlm.nih.gov/pubmed/32528159 A multiethnic genome-wide analysis of 44,039 individuals identifies 41 new loci associated with central corneal thickness. Central corneal thickness 32,292 European ancestry individuals, 9,623 East Asian ancestry individuals, 1,367 Hispanic/Latino individuals, 757 African American individuals NA Affymetrix [5541230] (imputed) 74 central corneal thickness http://www.ebi.ac.uk/efo/EFO_0005213 GCST90000654 Genome-wide genotyping array 44039 2020-09-14 32572055 Sekula P 2020-06-22 Sci Rep www.ncbi.nlm.nih.gov/pubmed/32572055 Urine 6-Bromotryptophan: Associations with Genetic Variants and Incident End-Stage Kidney Disease. Urine 6-bromotryptophan levels in chronic kidney disease 4,863 European ancestry individuals NA NR [9281895] (imputed) 2 urinary metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005116 GCST010559 Genome-wide genotyping array 4863 2020-10-08 32568366 Raghavan NS 2020-06-22 JAMA Neurol www.ncbi.nlm.nih.gov/pubmed/32568366 Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease. Brain amyloid deposition (PET imaging) 4,120 Europea ancestry individuals, 89 African American individuals, 105 Hispanic individuals NA Illumina [NR] (imputed) 16 amyloid-beta measurement http://www.ebi.ac.uk/efo/EFO_0005194 GCST010650 Genome-wide genotyping array 4314 2020-09-17 32579418 Maukonen M 2020-06-24 J Biol Rhythms www.ncbi.nlm.nih.gov/pubmed/32579418 Genetic Associations of Chronotype in the Finnish General Population. Chronotype (sMEQ score) 7,436 Finnish ancestry individuals NA Illumina [5842835] (imputed) 8 chronotype measurement http://www.ebi.ac.uk/efo/EFO_0008328 GCST010576 Genome-wide genotyping array 7436 2020-09-17 32579418 Maukonen M 2020-06-24 J Biol Rhythms www.ncbi.nlm.nih.gov/pubmed/32579418 Genetic Associations of Chronotype in the Finnish General Population. Evening vs. morning chronotype (sMEQ score) 2,364 Finnish ancestry evening individuals, 5,072 Finnish ancestry morning individuals NA Illumina [5842835] (imputed) 11 chronotype measurement http://www.ebi.ac.uk/efo/EFO_0008328 GCST010575 Genome-wide genotyping array 7436 2020-09-17 32579418 Maukonen M 2020-06-24 J Biol Rhythms www.ncbi.nlm.nih.gov/pubmed/32579418 Genetic Associations of Chronotype in the Finnish General Population. Evening vs. morning chronotype (self-assessed) 3,759 Finnish ancestry evening individuals , 4,674 Finnish ancestry morning individuals NA Illumina [5842835] (imputed) 9 chronotype measurement http://www.ebi.ac.uk/efo/EFO_0008328 GCST010574 Genome-wide genotyping array 8433 2020-08-03 32376702 Shen J 2020-05-06 mSphere www.ncbi.nlm.nih.gov/pubmed/32376702 Genetic Association Reveals Protection against Recurrence of Clostridium difficile Infection with Bezlotoxumab Treatment. Recurrence of Clostridium difficile infection x bezlotuxumab treatment interaction (2df test) 704 European, African American and Asian ancestry individuals NA Affymetrix [7570264] (imputed) 1 clostridium difficile infection, response to bezlotoxumab http://www.ebi.ac.uk/efo/EFO_0009130, http://www.ebi.ac.uk/efo/EFO_0010730 GCST010380 Genome-wide genotyping array 704 2020-06-23 32366958 Woodbury-Smith MR 2020-05-04 Sci Rep www.ncbi.nlm.nih.gov/pubmed/32366958 Genome-wide association study of emotional empathy in children. Emotional recognition 4,780 European ancestry children NA Illumina [27449291] (imputed) 3 facial emotion recognition measurement http://www.ebi.ac.uk/efo/EFO_0008329 GCST010093 Genome-wide genotyping array 4780 2020-06-23 32366958 Woodbury-Smith MR 2020-05-04 Sci Rep www.ncbi.nlm.nih.gov/pubmed/32366958 Genome-wide association study of emotional empathy in children. Emotional recognition 2,382 European ancestry boys NA Illumina [27449291] (imputed) 8 facial emotion recognition measurement http://www.ebi.ac.uk/efo/EFO_0008329 GCST010094 Genome-wide genotyping array 2382 2020-06-23 32366958 Woodbury-Smith MR 2020-05-04 Sci Rep www.ncbi.nlm.nih.gov/pubmed/32366958 Genome-wide association study of emotional empathy in children. Emotional recognition 2,393 European ancestry girls NA Illumina [27449291] (imputed) 2 facial emotion recognition measurement http://www.ebi.ac.uk/efo/EFO_0008329 GCST010095 Genome-wide genotyping array 2393 2020-08-03 32373937 Dardani C 2020-05-06 Int J Epidemiol www.ncbi.nlm.nih.gov/pubmed/32373937 Cleft lip/palate and educational attainment: cause, consequence or correlation? A Mendelian-randomization study. Cleft lip with or without cleft palate 1,692 European ancestry cases, 4,259 European ancestry controls NA NR [7618724] (imputed) 9 cleft lip http://www.ebi.ac.uk/efo/EFO_0003959 GCST010379 Genome-wide genotyping array 5951 2020-05-21 31969693 Coleman JRI 2020-01-23 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/31969693 Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. Major depressive disorder 29,475 European ancestry cases, 63,482 European ancestry controls NA Affymetrix [7791636] (imputed) 67 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST009979 Genome-wide genotyping array 92957 2020-05-21 31969693 Coleman JRI 2020-01-23 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/31969693 Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. Major depressive disorder in trauma exposed individuals 13,393 European ancestry cases, 10,701 European ancestry controls NA Affymetrix [7791636] (imputed) 21 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST009980 Genome-wide genotyping array 24094 2020-05-21 31969693 Coleman JRI 2020-01-23 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/31969693 Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. Major depressive disorder in trauma-unexposed individuals 9,487 European ancestry cases, 39,677 European ancestry controls NA Affymetrix [7791636] (imputed) 27 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST009981 Genome-wide genotyping array 49164 2020-05-21 31969693 Coleman JRI 2020-01-23 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/31969693 Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. Trauma exposure 35,269 European ancestry cases, 63,451 European ancestry controls NA Affymetrix [7791636] (imputed) 88 trauma exposure measurement http://www.ebi.ac.uk/efo/EFO_0010703 GCST009982 Genome-wide genotyping array 98720 2020-05-21 31969693 Coleman JRI 2020-01-23 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/31969693 Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. Trauma exposure in major depressive disorder 13,393 European ancestry cases, 9,487 European ancestry controls NA Affymetrix [7791636] (imputed) 19 trauma exposure measurement http://www.ebi.ac.uk/efo/EFO_0010703 GCST009983 Genome-wide genotyping array 22880 2020-05-21 31969693 Coleman JRI 2020-01-23 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/31969693 Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. Trauma exposure in major depressive disorder-negative individuals 10,701 European ancestry cases, 39,677 European ancestry controls NA Affymetrix [7791636] (imputed) 36 trauma exposure measurement http://www.ebi.ac.uk/efo/EFO_0010703 GCST009984 Genome-wide genotyping array 50378 2019-02-28 30677029 Riveros-McKay F 2019-01-24 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30677029 Genetic architecture of human thinness compared to severe obesity. Obese vs. thin 1,456 British ancestry obese children, 1,471 European ancestry thin adults up to 7,526 British ancestry obese individuals, 7,962 obese individuals, up to 3,532 British ancestry thin individuals, 8,106 thin individuals Illumina [41266535] (imputed) 14 obese body mass index status http://www.ebi.ac.uk/efo/EFO_0007041 GCST007240 Genome-wide genotyping array 2927 2019-02-28 30677029 Riveros-McKay F 2019-01-24 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30677029 Genetic architecture of human thinness compared to severe obesity. Obesity (extreme) 1,456 British ancestry obese children, 6,460 European ancestry control adults up to 7,526 British ancestry obese individuals, at least 4,405 obese individuals, up to 20,720 British ancestry controls, 61,166 controls Illumina [~ 41266535] (imputed) 13 obese body mass index status http://www.ebi.ac.uk/efo/EFO_0007041 GCST007241 Genome-wide genotyping array 7916 2019-02-28 30677029 Riveros-McKay F 2019-01-24 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30677029 Genetic architecture of human thinness compared to severe obesity. Normal body mass index vs. thin 1,471 European ancestry thin adults, 6,460 European ancestry control adults 3,532 British ancestry thin individuals, up to 20,720 British ancestry controls Illumina [41266535] (imputed) 2 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST007242 Genome-wide genotyping array 7931 2019-04-18 30674623 Syreeni A 2019-01-23 Diabetes www.ncbi.nlm.nih.gov/pubmed/30674623 Genetic Determinants of Glycated Hemoglobin in Type 1 Diabetes. Glycated hemoglobin levels in type 1 diabetes 4,622 Finnish ancestry individuals up to 3,097 individuals Illumina [8354674] (imputed) 1 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST007605 Genome-wide genotyping array 4622 2021-03-19 32588970 Lutz MW 2020-06-26 Alzheimers Dement www.ncbi.nlm.nih.gov/pubmed/32588970 Shared genetic etiology underlying late-onset Alzheimer's disease and posttraumatic stress syndrome. Alzheimer's disease or posttraumatic stress syndrome (pleiotropy) 21,982 LOAD cases, 41,994 controls, 2,424 European ancestry PTSD cases, 7,113 European ancestry controls, 1,968 African American LOAD cases, 2,479 African American PTSD cases, 10,672 African American controls 1011 PTSD cases, 1045 controls NR [9154389] (imputed) 0 Alzheimer's disease, post-traumatic stress disorder http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0001358 GCST011300 Genome-wide genotyping array 88632 2020-09-10 32569378 Clay-Gilmour AI 2020-06-01 Blood Adv www.ncbi.nlm.nih.gov/pubmed/32569378 Coinherited genetics of multiple myeloma and its precursor, monoclonal gammopathy of undetermined significance. Multiple myeloma 2,434 European ancestry cases, 2,705 European ancestry controls NA Affymetrix, Illumina [5864648] (imputed) 1 multiple myeloma http://www.ebi.ac.uk/efo/EFO_0001378 GCST010508 Genome-wide genotyping array 5139 2020-09-10 32569378 Clay-Gilmour AI 2020-06-01 Blood Adv www.ncbi.nlm.nih.gov/pubmed/32569378 Coinherited genetics of multiple myeloma and its precursor, monoclonal gammopathy of undetermined significance. Monoclonal gammopathy of undetermined significance 754 European ancestry cases, 879 European ancestry controls NA Illumina [5864648] (imputed) 0 monoclonal gammopathy http://www.ebi.ac.uk/efo/EFO_0000203 GCST010507 Genome-wide genotyping array 1633 2020-09-23 32581250 Lin Y 2020-06-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32581250 Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer. Pancreatic cancer 2,039 Japanese ancestry cases, 32,592 Japanese ancestry controls 1,926 East Asian cases, 8,896 East Asian controls Illumina [7914378] (imputed) 0 pancreatic carcinoma http://www.ebi.ac.uk/efo/EFO_0002618 GCST010616 Genome-wide genotyping array 34631 2020-12-24 32492067 Ruffieux H 2020-06-03 PLoS Comput Biol www.ncbi.nlm.nih.gov/pubmed/32492067 A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma. Protein quantitative trait loci 376 European ancestry individuals 400 European ancestry individuals Illumina [~ 4000000] (imputed) 7 protein measurement http://www.ebi.ac.uk/efo/EFO_0004747 GCST010901 Genome-wide genotyping array 376 2020-12-24 32492067 Ruffieux H 2020-06-03 PLoS Comput Biol www.ncbi.nlm.nih.gov/pubmed/32492067 A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma. Protein quantitative trait loci 394 European ancestry individuals 548 European ancestry individuals Illumina [~ 4000000] (imputed) 78 protein measurement http://www.ebi.ac.uk/efo/EFO_0004747 GCST010900 Genome-wide genotyping array 394 2020-12-24 32492067 Ruffieux H 2020-06-03 PLoS Comput Biol www.ncbi.nlm.nih.gov/pubmed/32492067 A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma. Protein quantitative trait loci 400 European ancestry individuals NA Illumina [~ 4000000] (imputed) 0 protein measurement http://www.ebi.ac.uk/efo/EFO_0004747 GCST010899 Genome-wide genotyping array 400 2020-12-24 32492067 Ruffieux H 2020-06-03 PLoS Comput Biol www.ncbi.nlm.nih.gov/pubmed/32492067 A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma. Protein quantitative trait loci 548 European ancestry individuals NA Illumina [~ 4000000] (imputed) 0 protein measurement http://www.ebi.ac.uk/efo/EFO_0004747 GCST010898 Genome-wide genotyping array 548 2020-12-24 32492067 Ruffieux H 2020-06-03 PLoS Comput Biol www.ncbi.nlm.nih.gov/pubmed/32492067 A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma. Protein quantitative trait loci up to 376 European ancestry individuals up to 400 European ancestry individuals Illumina [275297] (imputed) 0 protein measurement http://www.ebi.ac.uk/efo/EFO_0004747 GCST010897 Genome-wide genotyping array 376 2020-12-24 32492067 Ruffieux H 2020-06-03 PLoS Comput Biol www.ncbi.nlm.nih.gov/pubmed/32492067 A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma. Protein quantitative trait loci up to 394 European ancestry individuals up to 548 European ancestry individuals Illumina [275485] (imputed) 0 protein measurement http://www.ebi.ac.uk/efo/EFO_0004747 GCST010896 Genome-wide genotyping array 394 2021-02-25 32700739 Salinas YD 2020-07-23 Am J Epidemiol www.ncbi.nlm.nih.gov/pubmed/32700739 Discovery and Mediation Analysis of Cross-Phenotype Associations With Asthma and Body Mass Index in 12q13.2. Asthma 35,373 British ancestry cases, 270,572 British ancestry controls NA Affymetrix [528797] 1 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST011157 Genome-wide genotyping array 305945 2021-02-25 32700739 Salinas YD 2020-07-23 Am J Epidemiol www.ncbi.nlm.nih.gov/pubmed/32700739 Discovery and Mediation Analysis of Cross-Phenotype Associations With Asthma and Body Mass Index in 12q13.2. Body mass index 305,945 British ancestry individuals NA Affymetrix [528797] 1 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST011156 Genome-wide genotyping array 305945 2021-02-24 32701715 Zhang Y 2020-07-21 J Bone Joint Surg Am www.ncbi.nlm.nih.gov/pubmed/32701715 PPARGC1B Is Associated with Nontraumatic Osteonecrosis of the Femoral Head: A Genomewide Association Study on a Chart-Reviewed Cohort. Nontraumatic osteonecrosis of the femoral head 118 European ancestry cases, 56,811 European ancestry controls NA Illumina [3905175] (imputed) 24 idiopathic osteonecrosis of the femoral head http://www.ebi.ac.uk/efo/EFO_1001930 GCST011155 Genome-wide genotyping array 56929 2020-06-26 25576479 Berardi C 2015-01-10 Hum Genet www.ncbi.nlm.nih.gov/pubmed/25576479 Multi-ethnic analysis reveals soluble L-selectin may be post-transcriptionally regulated by 3'UTR polymorphism: the Multi-Ethnic Study of Atherosclerosis (MESA). L-selectin levels 620 European ancestry individuals, 600 Chinese ancestry individuals, 579 African American individuals, 604 Hispanic individuals NA Illumina [up to 418460] 23 L-Selectin measurement http://www.ebi.ac.uk/efo/EFO_0008202 GCST010107 Targeted genotyping array [Cardio-MetaboChip, Exome Array] 2403 2021-05-19 32699239 Jian X 2020-07-22 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32699239 Genome-wide association study of cognitive function in diverse Hispanics/Latinos: results from the Hispanic Community Health Study/Study of Latinos. Cognitive function 7,606 Hispanic individuals 43,875 European ancestry individuals, 10,399 African American individuals, 3,773 Hispanic individuals Illumina [20000000] (imputed) 0 cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0008354 GCST011695 Genome-wide genotyping array 7606 2020-06-24 32499645 Thaventhiran JED 2020-05-06 Nature www.ncbi.nlm.nih.gov/pubmed/32499645 Whole-genome sequencing of a sporadic primary immunodeficiency cohort. Antibody-deficiency-associated primary immunodeficiency 733 European, African, Asian and other ancestry cases, 9,225 European, African, Asian and other ancestry controls NA NR [8706207] 0 Primary immunodeficiency http://www.orpha.net/ORDO/Orphanet_101997 GCST90000530 Genome-wide sequencing 9958 2020-07-20 29343252 Hendry LM 2018-01-17 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/29343252 Insights into the genetics of blood pressure in black South African individuals: the Birth to Twenty cohort. Diastolic blood pressure 1,947 African ancestry individuals NA Illumina [125906] 2 diastolic blood pressure change measurement http://www.ebi.ac.uk/efo/EFO_0006945 GCST010216 Targeted genotyping array [Metabochip] 1947 2020-07-20 29343252 Hendry LM 2018-01-17 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/29343252 Insights into the genetics of blood pressure in black South African individuals: the Birth to Twenty cohort. Systolic blood pressure 1,947 African ancestry individuals NA Illumina [125906] 1 systolic blood pressure change measurement http://www.ebi.ac.uk/efo/EFO_0006944 GCST010217 Targeted genotyping array [Metabochip] 1947 2021-02-28 32699080 Brhane Y 2020-07-22 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/32699080 Genetic determinants of lung cancer prognosis in never smokers: A pooled analysis in the International Lung Cancer Consortium. Lung cancer (survival time) in never smokers 1,569 European ancestry individuals 887 Japanese ancestry individuals Illumina [629283] (imputed) 4 lung carcinoma, survival time http://www.ebi.ac.uk/efo/EFO_0001071, http://www.ebi.ac.uk/efo/EFO_0000714 GCST011178 Genome-wide genotyping array 1569 2021-02-28 32699080 Brhane Y 2020-07-22 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/32699080 Genetic determinants of lung cancer prognosis in never smokers: A pooled analysis in the International Lung Cancer Consortium. Lung adenocarcinoma (survival time) in never smokers 1,065 European ancestry individuals 871 Japanese ancestry individuals Illumina [629283] (imputed) 8 survival time, lung adenocarcinoma http://www.ebi.ac.uk/efo/EFO_0000714, http://www.ebi.ac.uk/efo/EFO_0000571 GCST011177 Genome-wide genotyping array 1065 2021-02-24 32682390 Wang W 2020-07-18 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/32682390 Heritability and genome-wide association analyses of fasting plasma glucose in Chinese adult twins. Fasting plasma glucose 382 Chinese ancestry twin pairs NA NR [7405822] (imputed) 17 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST011154 Genome-wide genotyping array 382 2020-09-04 32472697 Verma SS 2020-05-30 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/32472697 Genome-wide association study of platelet reactivity and cardiovascular response in patients treated with clopidogrel: a study by the International Clopidogrel Pharmacogenomics Consortium (ICPC). Cardiovascular death or myocardial infarction in response to clopidogrel treatment 102 European ancestry cases, 2,068 European ancestry controls NA Illumina [5009928] (imputed) 9 response to clopidogrel, cardiovascular event measurement http://purl.obolibrary.org/obo/GO_1903493, http://www.ebi.ac.uk/efo/EFO_0006919 GCST010482 Genome-wide genotyping array 2170 2020-09-04 32472697 Verma SS 2020-05-30 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/32472697 Genome-wide association study of platelet reactivity and cardiovascular response in patients treated with clopidogrel: a study by the International Clopidogrel Pharmacogenomics Consortium (ICPC). Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment 72 European ancestry cases, 1,375 European ancestry controls NA Illumina [5009928] (imputed) 6 stroke, response to clopidogrel, cardiovascular event measurement http://www.ebi.ac.uk/efo/EFO_0000712, http://purl.obolibrary.org/obo/GO_1903493, http://www.ebi.ac.uk/efo/EFO_0006919 GCST010483 Genome-wide genotyping array 1447 2020-09-04 32472697 Verma SS 2020-05-30 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/32472697 Genome-wide association study of platelet reactivity and cardiovascular response in patients treated with clopidogrel: a study by the International Clopidogrel Pharmacogenomics Consortium (ICPC). Stent thrombosis in response to clopidogrel treatment 37 European ancestry cases, 2,542 European ancestry controls NA Illumina [5009928] (imputed) 6 response to clopidogrel, cardiovascular event measurement http://purl.obolibrary.org/obo/GO_1903493, http://www.ebi.ac.uk/efo/EFO_0006919 GCST010484 Genome-wide genotyping array 2579 2020-09-04 32472697 Verma SS 2020-05-30 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/32472697 Genome-wide association study of platelet reactivity and cardiovascular response in patients treated with clopidogrel: a study by the International Clopidogrel Pharmacogenomics Consortium (ICPC). Platelet reactivity in response to clopidogrel treatment 2,592 European ancestry individuals NA Illumina [5009928] (imputed) 20 platelet reactivity measurement, response to clopidogrel http://www.ebi.ac.uk/efo/EFO_0004985, http://purl.obolibrary.org/obo/GO_1903493 GCST010485 Genome-wide genotyping array 2592 2019-01-28 30598549 Morris JA 2018-12-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30598549 An atlas of genetic influences on osteoporosis in humans and mice. Heel bone mineral density 426,824 British ancestry individuals NA NR [13737936] (imputed) 1103 heel bone mineral density http://www.ebi.ac.uk/efo/EFO_0009270 GCST006979 Genome-wide genotyping array 426824 2019-01-28 30598549 Morris JA 2018-12-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30598549 An atlas of genetic influences on osteoporosis in humans and mice. Fractures 53,184 British ancestry cases, 373,611 British ancestry controls 367,900 European ancestry cases, 363,919 European ancestry controls NR [13977204] (imputed) 14 bone fracture http://www.ebi.ac.uk/efo/EFO_0003931 GCST006980 Genome-wide genotyping array 426795 2021-02-28 32693751 Keene KL 2020-07-22 Stroke www.ncbi.nlm.nih.gov/pubmed/32693751 Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke. Stroke 3,734 African ancestry cases, 18,317 African ancestry controls NA Affymetrix, Illumina [~ 16900000] (imputed) 26 stroke http://www.ebi.ac.uk/efo/EFO_0000712 GCST011176 Genome-wide genotyping array 22051 2021-01-26 31668963 Bay CP 2019-09-27 J Clin Densitom www.ncbi.nlm.nih.gov/pubmed/31668963 Genome-Wide Association Analysis of Longitudinal Bone Mineral Content Data From the Iowa Bone Development Study. Hip bone mineral content accrual during adolescent growth spurt 125 women, 133 men NA Illumina [509842] 5 bone mineral content measurement http://www.ebi.ac.uk/efo/EFO_0007621 GCST010986 Genome-wide genotyping array 258 2021-01-26 31668963 Bay CP 2019-09-27 J Clin Densitom www.ncbi.nlm.nih.gov/pubmed/31668963 Genome-Wide Association Analysis of Longitudinal Bone Mineral Content Data From the Iowa Bone Development Study. Peak hip bone mineral content 190 women, 174 men NA Illumina [509842] 7 bone mineral content measurement http://www.ebi.ac.uk/efo/EFO_0007621 GCST010987 Genome-wide genotyping array 364 2021-02-26 33430853 Ustinova M 2021-01-11 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/33430853 Novel susceptibility loci identified in a genome-wide association study of type 2 diabetes complications in population of Latvia. Diabetic neuropathy in type 2 diabetes 218 European ancestry cases, 382 European ancestry controls NA Illumina [5378539] (imputed) 2 diabetic neuropathy http://www.ebi.ac.uk/efo/EFO_1000783 GCST011163 Genome-wide genotyping array 600 2021-02-26 33430853 Ustinova M 2021-01-11 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/33430853 Novel susceptibility loci identified in a genome-wide association study of type 2 diabetes complications in population of Latvia. Type 2 diabetes nephropathy 517 European ancestry cases, 84 European ancestry controls NA Illumina [5378539] (imputed) 0 diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0000401 GCST011162 Genome-wide genotyping array 601 2021-02-26 33430853 Ustinova M 2021-01-11 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/33430853 Novel susceptibility loci identified in a genome-wide association study of type 2 diabetes complications in population of Latvia. Macrovascular complications in type 2 diabetes 333 European ancestry cases, 226 European ancestry controls NA Illumina [5378539] (imputed) 7 macrovascular complications of diabetes http://www.ebi.ac.uk/efo/EFO_0010977 GCST011161 Genome-wide genotyping array 559 2021-02-26 33430853 Ustinova M 2021-01-11 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/33430853 Novel susceptibility loci identified in a genome-wide association study of type 2 diabetes complications in population of Latvia. Ophthalmic complications in type 2 diabetes 203 European ancestry cases, 398 European ancestry controls NA Illumina [5378539] (imputed) 1 diabetic eye disease http://www.ebi.ac.uk/efo/EFO_0009486 GCST011160 Genome-wide genotyping array 601 2021-02-02 33111402 Tan MMX 2020-10-28 Mov Disord www.ncbi.nlm.nih.gov/pubmed/33111402 Genome-Wide Association Studies of Cognitive and Motor Progression in Parkinson's Disease. Parkinson's disease progression (motor) 2,848 individuals NA Illumina [5918868] (imputed) 10 Parkinson's disease, disease progression measurement http://www.ebi.ac.uk/efo/EFO_0002508, http://www.ebi.ac.uk/efo/EFO_0008336 GCST011038 Genome-wide genotyping array, Genome-wide sequencing 2848 2021-02-02 33111402 Tan MMX 2020-10-28 Mov Disord www.ncbi.nlm.nih.gov/pubmed/33111402 Genome-Wide Association Studies of Cognitive and Motor Progression in Parkinson's Disease. Parkinson's disease progression (cognitive) 2,788 individuals NA Illumina [5918868] (imputed) 10 Parkinson's disease, disease progression measurement http://www.ebi.ac.uk/efo/EFO_0002508, http://www.ebi.ac.uk/efo/EFO_0008336 GCST011037 Genome-wide genotyping array, Genome-wide sequencing 2788 2021-02-02 33111402 Tan MMX 2020-10-28 Mov Disord www.ncbi.nlm.nih.gov/pubmed/33111402 Genome-Wide Association Studies of Cognitive and Motor Progression in Parkinson's Disease. Parkinson's disease progression (composite) 2,755 individuals NA Illumina [5918868] (imputed) 10 Parkinson's disease, disease progression measurement http://www.ebi.ac.uk/efo/EFO_0002508, http://www.ebi.ac.uk/efo/EFO_0008336 GCST011039 Genome-wide genotyping array, Genome-wide sequencing 2755 2021-07-09 33428804 Chalmer MA 2021-01-11 Eur J Neurol www.ncbi.nlm.nih.gov/pubmed/33428804 Chronic migraine: Genetics or environment? Migraine (chronic vs episodic) 127 Danish ancestry chronic migraine cases, 926 Danish ancestry episodic migraine cases NA Illumina [6101288] (imputed) 0 migraine disorder http://www.ebi.ac.uk/efo/EFO_0003821 GCST012023 Genome-wide genotyping array 1053 2021-07-09 33428804 Chalmer MA 2021-01-11 Eur J Neurol www.ncbi.nlm.nih.gov/pubmed/33428804 Chronic migraine: Genetics or environment? Migraine (proposed chronic vs episodic) 268 Danish ancestry proposed chronic migraine cases, 785 Danish ancestry episodic migraine cases NA Illumina [6101288] (imputed) 0 migraine disorder http://www.ebi.ac.uk/efo/EFO_0003821 GCST012022 Genome-wide genotyping array 1053 2021-03-30 33445220 Li Y 2021-01-14 Am J Transplant www.ncbi.nlm.nih.gov/pubmed/33445220 Donor genetic variants as risk factors for thrombosis after liver transplantation: A genome-wide association study. Thrombosis in response to liver transplant 42 European ancestry pediatric cases, 268 European ancestry pediatric controls 64 European ancestry adult cases, 711 European ancestry adult controls Illumina [5393447] (imputed) 11 coronary thrombosis, GM11992 http://www.ebi.ac.uk/efo/EFO_1000883, http://www.ebi.ac.uk/efo/EFO_0001124 GCST011434 Genome-wide genotyping array 310 2021-08-06 33437986 McGurk KA 2021-01-12 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33437986 Heritability and family-based GWAS analyses of the N-acyl ethanolamine and ceramide plasma lipidome. N-acyl ethanolamine levels 999 European ancestry individuals from 196 families NR Illumina [5280459] (imputed) 5 N-acylethanolamine measurement http://www.ebi.ac.uk/efo/EFO_0600028 GCST012173 Genome-wide genotyping array 1195 2021-08-06 33437986 McGurk KA 2021-01-12 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33437986 Heritability and family-based GWAS analyses of the N-acyl ethanolamine and ceramide plasma lipidome. Ceramide levels 999 European ancestry individuals from 196 families NR Illumina [5280459] (imputed) 13 ceramide measurement http://www.ebi.ac.uk/efo/EFO_0010222 GCST012172 Genome-wide genotyping array 1195 2018-09-12 29942086 Savage JE 2018-06-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29942086 Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. Intelligence 269,867 European ancestry individuals NA Affymetrix, Illumina [9295118] (imputed) 524 intelligence http://www.ebi.ac.uk/efo/EFO_0004337 GCST006250 Genome-wide genotyping array 269867 2020-07-06 32499647 Spracklen CN 2020-05-06 Nature www.ncbi.nlm.nih.gov/pubmed/32499647 Identification of type 2 diabetes loci in 433,540 East Asian individuals. Type 2 diabetes 77,418 East Asian cases, 356,122 East Asian controls NA Affymetrix, Illumina [11800000] (imputed) 183 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST010118 Genome-wide genotyping array 433540 2021-02-09 33113361 Iacoangeli A 2020-10-01 Cell Rep www.ncbi.nlm.nih.gov/pubmed/33113361 Genome-wide Meta-analysis Finds the ACSL5-ZDHHC6 Locus Is Associated with ALS and Links Weight Loss to the Disease Genetics. Amyotrophic lateral sclerosis 22,040 cases, 62,644 controls 837 European ancestry cases, 665 European ancestry controls NR [5356204] 0 amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0000253 GCST90013429 Genome-wide genotyping array 84684 2021-06-15 33239672 Laisk T 2020-11-25 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33239672 The genetic architecture of sporadic and multiple consecutive miscarriage. Sporadic miscarriage 49,996 European ancestry cases, 174,109 European ancestry controls NA Affymetrix, Illumina [9088459] (imputed) 1 fertility measurement http://www.ebi.ac.uk/efo/EFO_0006923 GCST011888 Genome-wide genotyping array 224105 2021-06-15 33239672 Laisk T 2020-11-25 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33239672 The genetic architecture of sporadic and multiple consecutive miscarriage. Multiple consecutive miscarriage 750 European ancestry cases, 150,215 European ancestry controls NA Affymetrix, Illumina [8956145] (imputed) 4 fertility measurement http://www.ebi.ac.uk/efo/EFO_0006923 GCST011887 Genome-wide genotyping array 150965 2021-06-15 33239672 Laisk T 2020-11-25 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33239672 The genetic architecture of sporadic and multiple consecutive miscarriage. Sporadic miscarriage 273 African ancestry cases, 2,919 African American cases, 390 Caribbean ancestry cases, 8,997 Chinese ancestry cases, 49,996 European ancestry cases, 1,151 Hispanic American cases, 511 South Asian ancestry cases, 482 African ancestry controls, 4,546 African American controls, 957 Caribbean ancestry controls, 126,723 Chinese ancestry controls, 174,109 European ancestry controls, 2,195 Hispanic American controls, 1,424 South Asian ancestry controls NA Affymetrix, Illumina [8664066] (imputed) 1 fertility measurement http://www.ebi.ac.uk/efo/EFO_0006923 GCST011889 Genome-wide genotyping array, Genome-wide sequencing 374673 2021-07-12 33436679 Chou YC 2021-01-12 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33436679 Integration of genome-wide association study and expression quantitative trait locus mapping for identification of endometriosis-associated genes. Endometriosis 126 Taiwanese ancestry cases, 96 Taiwanese ancestry controls 133 Taiwanese ancestry cases, 75 Taiwanese ancestry controls Affymetrix [4566885] (imputed) 2 endometriosis http://www.ebi.ac.uk/efo/EFO_0001065 GCST012024 Genome-wide genotyping array 222 2020-08-14 32572223 Hughes DA 2020-06-22 Nat Microbiol www.ncbi.nlm.nih.gov/pubmed/32572223 Genome-wide associations of human gut microbiome variation and implications for causal inference analyses. Gut microbiota (bacterial taxa, hurdle binary method) 2,223 European ancestry individuals 1,667 European ancestry individuals Illumina [7711310] (imputed) 319 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST010396 Genome-wide genotyping array 2223 2020-08-14 32572223 Hughes DA 2020-06-22 Nat Microbiol www.ncbi.nlm.nih.gov/pubmed/32572223 Genome-wide associations of human gut microbiome variation and implications for causal inference analyses. Gut microbiota (bacterial taxa, rank normal transformation method) 2,223 European ancestry individuals 1,667 European ancestry individuals Illumina [7711310] (imputed) 118 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST010397 Genome-wide genotyping array 2223 2020-01-28 31676860 Zhao B 2019-11-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31676860 Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits. Brain region volumes 21,821 European ancestry individuals NA NR [8938185] (imputed) 0 brain volume measurement http://www.ebi.ac.uk/efo/EFO_0006930 GCST009519 Genome-wide genotyping array 21821 2020-01-28 31676860 Zhao B 2019-11-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31676860 Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits. Brain region volumes 19,629 British ancestry individuals NA NR [9227495] (imputed) 1080 brain volume measurement http://www.ebi.ac.uk/efo/EFO_0006930 GCST009518 Genome-wide genotyping array 19629 2019-04-03 30801121 O'Donnell S 2019-02-25 Inflamm Bowel Dis www.ncbi.nlm.nih.gov/pubmed/30801121 The Unsolved Link of Genetic Markers and Crohn's Disease Progression: A North American Cohort Experience. Crohn's disease (time to progression) 662 European ancestry individuals NA Illumina [5378266] (imputed) 12 disease progression measurement, Crohn's disease http://www.ebi.ac.uk/efo/EFO_0008336, http://www.ebi.ac.uk/efo/EFO_0000384 GCST007497 Genome-wide genotyping array 662 2019-04-03 30801121 O'Donnell S 2019-02-25 Inflamm Bowel Dis www.ncbi.nlm.nih.gov/pubmed/30801121 The Unsolved Link of Genetic Markers and Crohn's Disease Progression: A North American Cohort Experience. Crohn's disease (time to first abdominal surgery) 1,360 European ancestry individuals NA Illumina [5378266] (imputed) 7 disease progression measurement, Crohn's disease http://www.ebi.ac.uk/efo/EFO_0008336, http://www.ebi.ac.uk/efo/EFO_0000384 GCST007498 Genome-wide genotyping array 1360 2019-04-03 30801121 O'Donnell S 2019-02-25 Inflamm Bowel Dis www.ncbi.nlm.nih.gov/pubmed/30801121 The Unsolved Link of Genetic Markers and Crohn's Disease Progression: A North American Cohort Experience. Crohn's disease (indolent vs progressive) 562 European ancestry individuals with indolent disease, 701 European ancestry individuals with progressive disease NA Illumina [5378266] (imputed) 15 disease progression measurement, Crohn's disease http://www.ebi.ac.uk/efo/EFO_0008336, http://www.ebi.ac.uk/efo/EFO_0000384 GCST007499 Genome-wide genotyping array 1263 2019-04-09 30808802 Freidin M 2019-02-26 J Med Genet www.ncbi.nlm.nih.gov/pubmed/30808802 Genome-wide meta-analysis identifies genetic locus on chromosome 9 associated with Modic changes. Modic changes 994 European ancestry cases, 835 European ancestry controls NA Illumina [5479070] (imputed) 10 Modic type vertebral endplate changes http://purl.obolibrary.org/obo/HP_0030775 GCST007537 Genome-wide genotyping array 1829 2019-09-25 30810208 Nishiyama T 2019-02-22 Sleep www.ncbi.nlm.nih.gov/pubmed/30810208 Genome-wide association meta-analysis and Mendelian randomization analysis confirm ALDH2 influencing on sleep duration in the Japanese population. Sleep duration 31,230 Japanese ancestry individuals 5,140 Japanese ancestry individuals Illumina [5590918] (imputed) 0 sleep duration http://www.ebi.ac.uk/efo/EFO_0005271 GCST008770 Genome-wide genotyping array 31230 2019-04-04 30820047 Kunkle BW 2019-02-28 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30820047 Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Alzheimer's disease (late onset) 21,982 European ancestry cases, 41,944 European ancestry controls up to 13,292 European ancestry cases, up to 17,219 European ancestry controls Affymetrix, Illumina [11480632] (imputed) 24 late-onset Alzheimers disease http://www.ebi.ac.uk/efo/EFO_1001870 GCST007511 Genome-wide genotyping array 63926 2019-03-27 30824882 Gunjaca I 2019-03-01 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30824882 Genome-wide association meta-analysis for total thyroid hormone levels in Croatian population. Thyroxine levels 1,121 Croatian ancestry individuals NA NR [7597900] (imputed) 1 thyroxine measurement http://www.ebi.ac.uk/efo/EFO_0005130 GCST007428 Genome-wide genotyping array 1121 2019-03-27 30824882 Gunjaca I 2019-03-01 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30824882 Genome-wide association meta-analysis for total thyroid hormone levels in Croatian population. Triiodothyronine levels 623 Croatian ancestry individuals NA NR [8753628] (imputed) 3 triiodothyronine measurement http://www.ebi.ac.uk/efo/EFO_0008392 GCST007426 Genome-wide genotyping array 623 2019-03-27 30824882 Gunjaca I 2019-03-01 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30824882 Genome-wide association meta-analysis for total thyroid hormone levels in Croatian population. Triiodothyronine/thyroxine ratio 623 Croatian ancestry individuals NA NR [8752746] (imputed) 3 tri-iodothyronine/thyroxine ratio measurement http://www.ebi.ac.uk/efo/EFO_0009779 GCST007427 Genome-wide genotyping array 623 2019-03-19 30823506 Hong EP 2019-02-25 J Clin Med www.ncbi.nlm.nih.gov/pubmed/30823506 Genomic Variations in Susceptibility to Intracranial Aneurysm in the Korean Population. Intracranial aneurysm 250 Korean ancestry cases, 296 Korean ancestry controls NA Affymetrix [508192] 29 brain aneurysm http://www.ebi.ac.uk/efo/EFO_0003870 GCST007354 Genome-wide genotyping array 546 2019-03-25 30804566 Lane JM 2019-02-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30804566 Biological and clinical insights from genetics of insomnia symptoms. Insomnia symptoms (never/rarely vs. sometimes/usually) 345,022 European ancestry cases, 108,357 European ancestry controls 17,140 European ancestry cases, 61,850 European ancestry controls Affymetrix [14661600] (imputed) 49 insomnia measurement http://www.ebi.ac.uk/efo/EFO_0007876 GCST007387 Genome-wide genotyping array 453379 2019-03-25 30804566 Lane JM 2019-02-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30804566 Biological and clinical insights from genetics of insomnia symptoms. Insomnia symptoms (never/rarely vs. usually) 129,270 European ancestry cases, 108,357 European ancestry controls 17,140 European ancestry cases, 61,850 European ancestry controls Affymetrix [14661600] (imputed) 55 insomnia measurement http://www.ebi.ac.uk/efo/EFO_0007876 GCST007388 Genome-wide genotyping array 237627 2020-07-08 32024964 Gonzalez-Serna D 2020-02-05 Sci Rep www.ncbi.nlm.nih.gov/pubmed/32024964 A cross-disease meta-GWAS identifies four new susceptibility loci shared between systemic sclerosis and Crohn's disease. Crohn's disease or systemic sclerosis 2,281 European ancestry systemic sclerosis cases, 1,988 European ancestry Crohn’s disease cases, 7,388 European ancestry controls 3,453 European ancestry systemic sclerosis cases, 2,600 European ancestry Crohn’s disease cases, 7,180 European ancestry controls Illumina [5994231] (imputed) 4 systemic scleroderma, Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000717, http://www.ebi.ac.uk/efo/EFO_0000384 GCST010124 Genome-wide genotyping array 11657 2019-03-10 30818990 Yu D 2019-03-01 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/30818990 Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies. Tourette syndrome 4,271 European ancestry cases, 548 European ancestry cases from 207 families, 9,488 European ancestry controls 706 Icelandic ancestry cases, 6,068 Icelandic ancestry controls Illumina [8265319] (imputed) 24 Tourette syndrome http://www.ebi.ac.uk/efo/EFO_0004895 GCST007277 Genome-wide genotyping array 14514 2020-05-04 32232851 Deguchi H 2020-03-30 Br J Haematol www.ncbi.nlm.nih.gov/pubmed/32232851 Novel exomic rare variants associated with venous thrombosis. Venous thromboembolism 104 European ancestry cases, 211 European ancestry controls NA Illumina [308166] 22 venous thromboembolism http://www.ebi.ac.uk/efo/EFO_0004286 GCST009936 Exome genotyping array [Exome array] 315 2020-01-10 31791255 Vicente M 2019-12-02 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/31791255 Population history and genetic adaptation of the Fulani nomads: inferences from genome-wide data and the lactase persistence trait. Lactose tolerance test 53 Fulani individuals, 7 Czech or Slovak individuals NA Illumina [2359821] 2 lactose tolerance test http://www.ebi.ac.uk/efo/EFO_0010557 GCST009418 Genome-wide genotyping array 60 2018-08-24 29724592 Pottier C 2018-04-30 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/29724592 Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. Behavioural changes in frontotemporal lobe dementia 262 European ancestry cases, 120 European ancestry controls NA Illumina [7033776] (imputed) 3 behavior http://purl.obolibrary.org/obo/GO_0007610 GCST006146 Genome-wide genotyping array 382 2018-08-24 29724592 Pottier C 2018-04-30 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/29724592 Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. Frontotemporal dementia (age at onset) 382 European ancestry GRN mutation carrier individuals 67 European ancestry GRN mutation carrier individuals, 143 European ancestry GRN negative individuals Illumina [7033776] (imputed) 5 age at onset, Frontotemporal dementia http://www.ebi.ac.uk/efo/EFO_0004847, http://www.orpha.net/ORDO/Orphanet_282 GCST006147 Genome-wide genotyping array 382 2018-08-24 29724592 Pottier C 2018-04-30 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/29724592 Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. Frontotemporal dementia with GRN mutation 382 European ancestry cases, 1,146 European ancestry controls 67 European ancestry cases, 1,798 European ancestry controls Illumina [7033776] (imputed) 12 Frontotemporal dementia http://www.orpha.net/ORDO/Orphanet_282 GCST006148 Genome-wide genotyping array 1528 2018-08-24 29724592 Pottier C 2018-04-30 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/29724592 Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. Frontotemporal dementia with GRN mutation (age at onset) 382 European ancestry individuals 67 European ancestry individuals Illumina [7033776] (imputed) 6 age at onset, Frontotemporal dementia http://www.ebi.ac.uk/efo/EFO_0004847, http://www.orpha.net/ORDO/Orphanet_282 GCST006149 Genome-wide genotyping array 382 2018-08-24 29724592 Pottier C 2018-04-30 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/29724592 Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. Frontotemporal dementia 382 European ancestry GRN mutation carrier cases, 1,146 European ancestry controls 143 European ancestry GRN negative cases, 1,798 European ancestry controls Illumina [7033776] (imputed) 0 Frontotemporal dementia http://www.orpha.net/ORDO/Orphanet_282 GCST006150 Genome-wide genotyping array 1528 2018-08-24 29724592 Pottier C 2018-04-30 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/29724592 Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. Memory dysfunction in frontotemporal lobe dementia 139 European ancestry cases, 243 European ancestry controls NA Illumina [7033776] (imputed) 6 memory impairment http://www.ebi.ac.uk/efo/EFO_0001072 GCST006151 Genome-wide genotyping array 382 2018-08-24 29724592 Pottier C 2018-04-30 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/29724592 Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. Language impairment in frontotemporal lobe dementia 169 European ancestry cases, 213 European ancestry controls NA Illumina [7033776] (imputed) 2 language impairment http://www.ebi.ac.uk/efo/EFO_0005425 GCST006152 Genome-wide genotyping array 382 2018-08-24 29724592 Pottier C 2018-04-30 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/29724592 Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. Parkinsonism in frontotemporal lobe dementia 184 European ancestry cases, 198 European ancestry controls NA Illumina [7033776] (imputed) 3 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST006153 Genome-wide genotyping array 382 2018-08-24 29724592 Pottier C 2018-04-30 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/29724592 Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. Frontotemporal dementia 382 European ancestry GRN mutation carrier cases, 1,146 European ancestry controls 67 GRN mutation carrier European ancestry cases, 143 GRN-negative European ancestry cases, 1,798 European ancestry controls Illumina [7033776] (imputed) 6 Frontotemporal dementia http://www.orpha.net/ORDO/Orphanet_282 GCST006154 Genome-wide genotyping array 1528 2020-11-05 32868391 Leng RX 2020-08-31 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/32868391 Identification of new susceptibility loci associated with rheumatoid arthritis. Rheumatoid arthritis 5,900 East Asian cases, 20,521 East Asian controls, 14,361 European ancestry cases, 43,923 European ancestry controls NA Illumina [NR] (imputed) 5 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST010730 Genome-wide genotyping array 84705 2018-12-07 29947131 Smit DJA 2018-06-26 Hum Brain Mapp www.ncbi.nlm.nih.gov/pubmed/29947131 Genome-wide association analysis links multiple psychiatric liability genes to oscillatory brain activity. Electroencephalogram traits up to 8,425 European and unknown ancestry individuals NA Affymetrix, Illumina, Perlegen [at least 4959085] (imputed) 8 electroencephalogram measurement http://www.ebi.ac.uk/efo/EFO_0004357 GCST006684 Genome-wide genotyping array 8425 2018-10-17 29942513 Penney ME 2018-06-13 Biomark Res www.ncbi.nlm.nih.gov/pubmed/29942513 Associations of single nucleotide polymorphisms with mucinous colorectal cancer: genome-wide common variant and gene-based rare variant analyses. Mucinous adenocarcinoma in colorectal cancer 57 European ancestry cases, 448 European ancestry controls NA Illumina [729373] 17 colorectal mucinous adenocarcinoma http://www.ebi.ac.uk/efo/EFO_0009361 GCST006411 Genome-wide genotyping array 505 2018-09-19 29959729 Zhong XL 2018-06-29 Neurotox Res www.ncbi.nlm.nih.gov/pubmed/29959729 A Genome-Wide Association Study of α-Synuclein Levels in Cerebrospinal Fluid. Cerebrospinal fluid α-synuclein levels 59 European ancestry individuals with normal cognition, 101 European ancestry individuals with mild cognitive impairment, 49 European ancestry Alzheimer's disease cases NA Illumina [519442] 6 cerebrospinal fluid biomarker measurement, alpha synuclein measurement http://www.ebi.ac.uk/efo/EFO_0006794, http://www.ebi.ac.uk/efo/EFO_0009323 GCST006279 Genome-wide genotyping array 209 2020-02-10 28855172 den Hollander W 2017-08-30 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/28855172 Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand. Osteoarthritis of the hand 8,743 individuals 2,836 European ancestry individuals, 1,175 individuals Illumina [~ 11000000] (imputed) 5 osteoarthritis, hand http://www.ebi.ac.uk/efo/EFO_1000789 GCST009596 Genome-wide genotyping array 8743 2020-04-17 32099098 Polimanti R 2020-02-26 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32099098 Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium. Opioid dependence in opioid exposure 1,231 African ancestry cases, 3,272 European ancestry cases, 1,297 African ancestry controls, 2,876 European ancestry controls NA NR [up to 8956178] (imputed) 0 opioid dependence http://www.ebi.ac.uk/efo/EFO_0005611 GCST009854 Genome-wide genotyping array 8676 2020-04-17 32099098 Polimanti R 2020-02-26 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32099098 Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium. Opioid dependence 1,027 African ancestry cases, 3,211 European ancestry cases, 6,111 African ancestry controls, 11,589 European ancestry controls NA NR [up to 8896928] (imputed) 1 opioid dependence http://www.ebi.ac.uk/efo/EFO_0005611 GCST009853 Genome-wide genotyping array 21938 2020-04-17 32099098 Polimanti R 2020-02-26 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32099098 Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium. Opioid exposure 1,297 African ancestry cases, 2,876 European ancestry cases, 7,063 African ancestry controls, 25,437 European ancestry controls NA NR [up to 9065342] (imputed) 3 Opioid use measurement http://www.ebi.ac.uk/efo/EFO_0009937 GCST009852 Genome-wide genotyping array 36673 2020-07-08 32382064 Pirruccello JP 2020-05-07 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32382064 Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy. Left ventricular end-diastolic volume 35,407 European ancestry individuals, 95 African ancestry individuals, 108 East Asian ancestry individuals, 303 South Asian ancestry individuals, 128 individuals 940 European ancestry individuals, 299 East Asian ancestry individuals, 507 African American individuals, 438 Hispanic individuals Affymetrix [13660711] (imputed) 2 left ventricular diastolic function measurement http://www.ebi.ac.uk/efo/EFO_0008204 GCST010131 Genome-wide genotyping array 36041 2020-07-08 32382064 Pirruccello JP 2020-05-07 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32382064 Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy. Left ventricular end-systolic volume 35,407 European ancestry individuals, 95 African ancestry individuals, 108 East Asian ancestry individuals, 303 South Asian ancestry individuals, 128 individuals 940 European ancestry individuals, 299 East Asian ancestry individuals, 507 African American individuals, 438 Hispanic individuals Affymetrix [13660711] (imputed) 3 left ventricular systolic function measurement http://www.ebi.ac.uk/efo/EFO_0008206 GCST010130 Genome-wide genotyping array 36041 2020-07-08 32382064 Pirruccello JP 2020-05-07 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32382064 Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy. Left ventricular stroke volume 35,407 European ancestry individuals, 95 African ancestry individuals, 108 East Asian ancestry individuals, 303 South Asian ancestry individuals, 128 individuals 940 European ancestry individuals, 299 East Asian ancestry individuals, 507 African American individuals, 438 Hispanic individuals Affymetrix [13660711] (imputed) 0 left ventricular stroke volume measurement http://www.ebi.ac.uk/efo/EFO_0010555 GCST010129 Genome-wide genotyping array 36041 2020-07-08 32382064 Pirruccello JP 2020-05-07 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32382064 Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy. Body surface area-indexed left ventricular end-diastolic volume 35,407 European ancestry individuals, 95 African ancestry individuals, 108 East Asian ancestry individuals, 303 South Asian ancestry individuals, 128 individuals 940 European ancestry individuals, 299 East Asian ancestry individuals, 507 African American individuals, 438 Hispanic individuals Affymetrix [13660711] (imputed) 0 left ventricular diastolic function measurement http://www.ebi.ac.uk/efo/EFO_0008204 GCST010128 Genome-wide genotyping array 36041 2020-07-08 32382064 Pirruccello JP 2020-05-07 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32382064 Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy. Body surface area-indexed left ventricular end-systolic volume 35,407 European ancestry individuals, 95 African ancestry individuals, 108 East Asian ancestry individuals, 303 South Asian ancestry individuals, 128 individuals 940 European ancestry individuals, 299 East Asian ancestry individuals, 507 African American individuals, 438 Hispanic individuals Affymetrix [13660711] (imputed) 0 left ventricular systolic function measurement http://www.ebi.ac.uk/efo/EFO_0008206 GCST010127 Genome-wide genotyping array 36041 2020-07-08 32382064 Pirruccello JP 2020-05-07 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32382064 Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy. Body surface area-indexed left ventricular stroke volume 35,407 European ancestry individuals, 95 African ancestry individuals, 108 East Asian ancestry individuals, 303 South Asian ancestry individuals, 128 individuals 940 European ancestry individuals, 299 East Asian ancestry individuals, 507 African American individuals, 438 Hispanic individuals Affymetrix [13660711] (imputed) 0 left ventricular stroke volume measurement http://www.ebi.ac.uk/efo/EFO_0010555 GCST010126 Genome-wide genotyping array 36041 2020-07-08 32382064 Pirruccello JP 2020-05-07 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32382064 Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy. Left ventricular ejection fraction 35,407 European ancestry individuals, 95 African ancestry individuals, 108 East Asian ancestry individuals, 303 South Asian ancestry individuals, 128 individuals 940 European ancestry individuals, 299 East Asian ancestry individuals, 507 African American individuals, 438 Hispanic individuals Affymetrix [13660711] (imputed) 4 left ventricular ejection fraction measurement http://www.ebi.ac.uk/efo/EFO_0008373 GCST010125 Genome-wide genotyping array 36041 2020-03-02 31361310 Johansson A 2019-07-30 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31361310 Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema. Allergic rhinitis 18,915 European ancestry cases, 239,773 European ancestry controls NA Affymetrix [15688218] (imputed) 27 allergic rhinitis http://www.ebi.ac.uk/efo/EFO_0005854 GCST009719 Genome-wide genotyping array 258688 2020-03-02 31361310 Johansson A 2019-07-30 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31361310 Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema. Eczema 7,884 European ancestry cases, 239,773 European ancestry controls 21,000 cases, 96,000 controls Affymetrix [15688218] (imputed) 16 Eczema http://purl.obolibrary.org/obo/HP_0000964 GCST009718 Genome-wide genotyping array 247657 2020-03-02 31361310 Johansson A 2019-07-30 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31361310 Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema. Hay fever and/or eczema 84,034 European ancestry cases, 239,773 European ancestry controls NA Affymetrix [15688218] (imputed) 154 Eczema, allergic rhinitis http://purl.obolibrary.org/obo/HP_0000964, http://www.ebi.ac.uk/efo/EFO_0005854 GCST009717 Genome-wide genotyping array 323807 2020-03-02 31361310 Johansson A 2019-07-30 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31361310 Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema. Allergic disease (asthma, hay fever or eczema) 106,772 European ancestry cases, 239,773 European ancestry controls 83,335 cases, 34,934 controls Affymetrix [15688218] (imputed) 85 Eczema, allergic rhinitis, asthma http://purl.obolibrary.org/obo/HP_0000964, http://www.ebi.ac.uk/efo/EFO_0005854, http://www.ebi.ac.uk/efo/EFO_0000270 GCST009716 Genome-wide genotyping array 346545 2020-03-02 31361310 Johansson A 2019-07-30 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31361310 Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema. Asthma 41,926 European ancestry cases, 239,773 European ancestry controls 10,365 cases, 16,100 controls Affymetrix [15688218] (imputed) 101 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST009720 Genome-wide genotyping array 281699 2020-06-25 27532455 Sun W 2016-08-17 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/27532455 Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD. Blood protein levels 1,340 European ancestry individuals NA Illumina [NR] 137 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST010104 Genome-wide genotyping array 1340 2020-06-08 32141793 Garman L 2020-03-06 Ocul Immunol Inflamm www.ncbi.nlm.nih.gov/pubmed/32141793 Genome-Wide Association Study of Ocular Sarcoidosis Confirms HLA Associations and Implicates Barrier Function and Autoimmunity in African Americans. Ocular sarcoidosis 260 African American cases, 1,551 African American controls NA Illumina [13976150] (imputed) 84 ocular sarcoidosis http://www.ebi.ac.uk/efo/EFO_0010723 GCST010054 Genome-wide genotyping array 1811 2020-06-08 32141793 Garman L 2020-03-06 Ocul Immunol Inflamm www.ncbi.nlm.nih.gov/pubmed/32141793 Genome-Wide Association Study of Ocular Sarcoidosis Confirms HLA Associations and Implicates Barrier Function and Autoimmunity in African Americans. Ocular sarcoidosis in sarcoidosis 260 African American cases, 513 African American controls NA Illumina [13976150] (imputed) 4 ocular sarcoidosis http://www.ebi.ac.uk/efo/EFO_0010723 GCST010052 Genome-wide genotyping array 773 2020-06-08 32141793 Garman L 2020-03-06 Ocul Immunol Inflamm www.ncbi.nlm.nih.gov/pubmed/32141793 Genome-Wide Association Study of Ocular Sarcoidosis Confirms HLA Associations and Implicates Barrier Function and Autoimmunity in African Americans. Ocular sarcoidosis 35 European ancestry cases, 2,046 European ancestry controls NA Illumina [4755887] (imputed) 18 ocular sarcoidosis http://www.ebi.ac.uk/efo/EFO_0010723 GCST010053 Genome-wide genotyping array 2081 2020-06-08 32141793 Garman L 2020-03-06 Ocul Immunol Inflamm www.ncbi.nlm.nih.gov/pubmed/32141793 Genome-Wide Association Study of Ocular Sarcoidosis Confirms HLA Associations and Implicates Barrier Function and Autoimmunity in African Americans. Ocular sarcoidosis in sarcoidosis 35 European ancestry cases, 221 European ancestry controls NA Illumina [4755887] (imputed) 2 ocular sarcoidosis http://www.ebi.ac.uk/efo/EFO_0010723 GCST010051 Genome-wide genotyping array 256 2019-05-15 30805717 Zhu Z 2019-02-25 Hum Genet www.ncbi.nlm.nih.gov/pubmed/30805717 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis. Alzheimer's disease or fasting glucose levels (pleiotropy) 54,162 European ancestry cases, 58,047 European ancestry individuals NA NR [NR] 4 Alzheimer's disease, fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0004465 GCST007825 Genome-wide genotyping array 112209 2019-05-15 30805717 Zhu Z 2019-02-25 Hum Genet www.ncbi.nlm.nih.gov/pubmed/30805717 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis. Alzheimer's disease or fasting insulin levels (pleiotropy) 54,162 European ancestry cases, 51,750 European ancestry individuals NA NR [NR] 3 Alzheimer's disease, fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0004466 GCST007826 Genome-wide genotyping array 105912 2019-05-15 30805717 Zhu Z 2019-02-25 Hum Genet www.ncbi.nlm.nih.gov/pubmed/30805717 Shared genetic architecture between metabolic traits and Alzheimer's disease: a large-scale genome-wide cross-trait analysis. Alzheimer's disease or HDL levels (pleiotropy) 54,162 European ancestry cases, 60,812 European ancestry individuals NA NR [NR] 20 Alzheimer's disease, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0004612 GCST007827 Genome-wide genotyping array 114974 2019-03-22 30807572 Gong J 2019-02-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30807572 Genetic association and transcriptome integration identify contributing genes and tissues at cystic fibrosis modifier loci. Meconium ileus in cystic fibrosis 1,115 European ancestry cases, 5,655 European ancestry controls NA Illumina [8763019] (imputed) 7 cystic fibrosis associated meconium ileus http://www.ebi.ac.uk/efo/EFO_0004608 GCST007367 Genome-wide genotyping array, Genome-wide sequencing 6770 2019-04-17 30818988 Klein M 2019-03-01 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/30818988 Genetic Markers of ADHD-Related Variations in Intracranial Volume. Attention deficit hyperactivity disorder or hippocampal volume (pleiotropy) 19,099 European ancestry ADHD cases, 1,084 ADHD cases, 34,194 European ancestry controls, 997 controls, 24,704 European ancestry individuals NA NR [up to 9145464] (imputed) 0 attention deficit hyperactivity disorder, hippocampal volume http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0005035 GCST007587 Genome-wide genotyping array 80078 2019-04-17 30818988 Klein M 2019-03-01 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/30818988 Genetic Markers of ADHD-Related Variations in Intracranial Volume. Attention deficit hyperactivity disorder or nucleus accumbens volume (pleiotropy) 19,099 European ancestry ADHD cases, 1,084 ADHD cases, 34,194 European ancestry controls, 997 controls, 11,709 European ancestry individuals NA NR [up to 8615659] (imputed) 0 attention deficit hyperactivity disorder, nucleus accumbens volume http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0006931 GCST007583 Genome-wide genotyping array 67083 2019-04-17 30818988 Klein M 2019-03-01 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/30818988 Genetic Markers of ADHD-Related Variations in Intracranial Volume. Attention deficit hyperactivity disorder or caudate nucleus volume (pleiotropy) 19,099 European ancestry ADHD cases, 1,084 ADHD cases, 34,194 European ancestry controls, 997 controls, 11,772 European ancestry individuals NA NR [up to 8615485] (imputed) 1 attention deficit hyperactivity disorder, caudate nucleus volume http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0004830 GCST007591 Genome-wide genotyping array 67146 2019-04-17 30818988 Klein M 2019-03-01 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/30818988 Genetic Markers of ADHD-Related Variations in Intracranial Volume. Hippocampal volume 24,704 European ancestry individuals NA NR [9145464] (imputed) 6 hippocampal volume http://www.ebi.ac.uk/efo/EFO_0005035 GCST007590 Genome-wide genotyping array 24704 2019-04-17 30818988 Klein M 2019-03-01 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/30818988 Genetic Markers of ADHD-Related Variations in Intracranial Volume. Intracranial volume 24,024 European ancestry individuals NA NR [9186920] (imputed) 7 intracranial volume measurement http://www.ebi.ac.uk/efo/EFO_0004886 GCST007589 Genome-wide genotyping array 24024 2019-04-17 30818988 Klein M 2019-03-01 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/30818988 Genetic Markers of ADHD-Related Variations in Intracranial Volume. Attention deficit hyperactivity disorder or intracranial volume (pleiotropy) 19,099 European ancestry ADHD cases, 1,084 ADHD cases, 34,194 European ancestry controls, 997 controls, 24,024 European ancestry individuals NA NR [up to 9186920] (imputed) 3 attention deficit hyperactivity disorder, intracranial volume measurement http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0004886 GCST007586 Genome-wide genotyping array 79398 2019-04-17 30818988 Klein M 2019-03-01 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/30818988 Genetic Markers of ADHD-Related Variations in Intracranial Volume. Attention deficit hyperactivity disorder or putamen volume (pleiotropy) 19,099 European ancestry ADHD cases, 1,084 ADHD cases, 34,194 European ancestry controls, 997 controls, 11,646 European ancestry individuals NA NR [up to 8609826] (imputed) 2 attention deficit hyperactivity disorder, putamen volume http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0006932 GCST007582 Genome-wide genotyping array 67020 2019-04-17 30818988 Klein M 2019-03-01 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/30818988 Genetic Markers of ADHD-Related Variations in Intracranial Volume. Attention deficit hyperactivity disorder or amygdala volume (pleiotropy) 19,099 European ancestry ADHD cases, 1,084 ADHD cases, 34,194 European ancestry controls, 997 controls, 11,757 European ancestry individuals NA NR [up to 8601199] (imputed) 1 attention deficit hyperactivity disorder, amygdala volume http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0006934 GCST007588 Genome-wide genotyping array 67131 2019-04-17 30818988 Klein M 2019-03-01 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/30818988 Genetic Markers of ADHD-Related Variations in Intracranial Volume. Attention deficit hyperactivity disorder or pallidum volume (pleiotropy) 19,099 European ancestry ADHD cases, 1,084 ADHD cases, 34,194 European ancestry controls, 997 controls, 11,640 European ancestry individuals NA NR [~ 8047420] (imputed) 0 attention deficit hyperactivity disorder, pallidum volume http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0006933 GCST007585 Genome-wide genotyping array 67014 2019-04-17 30818988 Klein M 2019-03-01 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/30818988 Genetic Markers of ADHD-Related Variations in Intracranial Volume. Attention deficit hyperactivity disorder or thalamus volume (pleiotropy) 19,099 European ancestry ADHD cases, 1,084 ADHD cases, 34,194 European ancestry controls, 997 controls, 11,694 European ancestry individuals NA NR [~ 8047420] (imputed) 0 attention deficit hyperactivity disorder, thalamus volume http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0006935 GCST007584 Genome-wide genotyping array 67068 2020-02-27 27352405 Balakrishnan P 2016-06-28 Environ Health Perspect www.ncbi.nlm.nih.gov/pubmed/27352405 Association of Cardiometabolic Genes with Arsenic Metabolism Biomarkers in American Indian Communities: The Strong Heart Family Study (SHFS). Arsenic metabolism 2,428 American Indian ancestry individuals NA Illumina [120975] 5 urinary arsenic measurement http://www.ebi.ac.uk/efo/EFO_0004880 GCST009703 Targeted genotyping array [Cardio-MetaboChip] 2428 2019-04-03 30809046 Schmitz B 2019-02-26 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30809046 Genome-wide association study suggests impact of chromosome 10 rs139401390 on kidney function in patients with coronary artery disease. Estimated glomerular filtration rate in coronary artery disease and impaired kidney function 499 European ancestry cases 574 European ancestry cases Affymetrix [> 10000000] (imputed) 2 glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0005208 GCST007495 Genome-wide genotyping array 499 2020-03-02 28913729 Ruiz-Pinto S 2017-09-14 Breast Cancer Res Treat www.ncbi.nlm.nih.gov/pubmed/28913729 Exome array analysis identifies ETFB as a novel susceptibility gene for anthracycline-induced cardiotoxicity in cancer patients. Anthracycline-induced cardiotoxicity 53 European ancestry breast cancer cases, 18 European ancestry controls 52 European ancestry breast cancer cases, 31 European ancestry controls Illumina [246060] 0 response to anthracycline-based chemotherapy http://www.ebi.ac.uk/efo/EFO_0005257 GCST009721 Exome genotyping array [Exome array] 71 2020-01-29 31844048 Hill WD 2019-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31844048 Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income. Household income (MTAG) 505,541 British and unknown ancestry individuals NA Affymetrix [up to 18485882] (imputed) 343 household income http://www.ebi.ac.uk/efo/EFO_0009695 GCST009524 Genome-wide genotyping array 505541 2020-01-29 31844048 Hill WD 2019-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31844048 Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income. Household income 286,301 British ancestry individuals NA Affymetrix [18485882] (imputed) 68 household income http://www.ebi.ac.uk/efo/EFO_0009695 GCST009523 Genome-wide genotyping array 286301 2020-02-10 31604244 International Multiple Sclerosis Genetics Consortium 2019-09-01 Science www.ncbi.nlm.nih.gov/pubmed/31604244 Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility. Multiple sclerosis 14,802 European and unknown ancestry cases, 26,703 European and unknown ancestry controls 32,627 European and unknown ancestry cases, 41,672 European and unknown ancestry controls Affymetrix, Illumina [8278136] (imputed) 333 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST009597 Genome-wide genotyping array 41505 2020-04-17 32117775 Wu J 2020-02-11 Front Oncol www.ncbi.nlm.nih.gov/pubmed/32117775 The Rare Variant rs35356162 in UHRF1BP1 Increases Bladder Cancer Risk in Han Chinese Population. Bladder cancer 995 Han Chinese ancestry cases, 1,008 Han Chinese ancestry controls 2,404 Han Chinese ancestry cases, 3,639 Han Chinese ancestry controls Illumina [270241] 2 bladder carcinoma http://www.ebi.ac.uk/efo/EFO_0000292 GCST009872 Exome genotyping array [Exome array] 2003 2020-04-17 32128391 Klaric L 2020-02-19 Sci Adv www.ncbi.nlm.nih.gov/pubmed/32128391 Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases. IgG N-glycosylation phenotypes (multivariate analysis) 8,090 European ancestry individuals 2,388 European ancestry individuals Illumina [up to 741151] (imputed) 11 serum IgG glycosylation measurement http://www.ebi.ac.uk/efo/EFO_0005193 GCST009860 Genome-wide genotyping array 8090 2021-04-30 32132452 Jin EH 2020-03-01 Clin Transl Gastroenterol www.ncbi.nlm.nih.gov/pubmed/32132452 A Novel Susceptibility Locus Near GRIK2 Associated With Erosive Esophagitis in a Korean Cohort. Erosive esophagitis 493 Korean ancestry male cases, 123 Korean ancestry female cases, 1,777 Korean ancestry male controls, 1,227 Korean ancestry female controls 100 Korean ancestry male cases, 32 Korean ancestry female cases, 297 Korean ancestry male controls, 193 Korean ancestry female controls Affymetrix [3693205] (imputed) 0 peptic esophagitis http://www.ebi.ac.uk/efo/EFO_1001095 GCST011585 Genome-wide genotyping array 3620 2020-05-28 32019955 Brcic L 2020-02-04 Sci Rep www.ncbi.nlm.nih.gov/pubmed/32019955 AATF and SMARCA2 are associated with thyroid volume in Hashimoto's thyroiditis patients. Thyroid volume in Hashimoto’s thyroiditis 345 European ancestry individuals NA Illumina [6007542] (imputed) 8 thyroid volume http://www.ebi.ac.uk/efo/EFO_0004865 GCST009997 Genome-wide genotyping array 345 2020-04-17 32141789 Theriault S 2019-10-15 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/32141789 Genetic Association Analyses Highlight IL6, ALPL, and NAV1 As 3 New Susceptibility Genes Underlying Calcific Aortic Valve Stenosis. Calcific aortic valve stenosis 5,115 European ancestry cases, 354,072 European ancestry controls NA Affymetrix, Illumina [8000000] (imputed) 26 aortic stenosis, aortic valve calcification http://www.ebi.ac.uk/efo/EFO_0000266, http://www.ebi.ac.uk/efo/EFO_0005239 GCST009870 Genome-wide genotyping array 359187 2020-04-17 32133506 Li H 2020-03-05 Schizophr Bull www.ncbi.nlm.nih.gov/pubmed/32133506 Genome-wide Association Study of Creativity Reveals Genetic Overlap With Psychiatric Disorders, Risk Tolerance, and Risky Behaviors. Creativity 4,664 Han Chinese ancestry individuals NA Illumina [up to 5481607] (imputed) 7 creativity measurement http://www.ebi.ac.uk/efo/EFO_0010650 GCST009844 Genome-wide genotyping array 4664 2021-05-19 32123936 Shiota M 2020-03-02 Cancer Immunol Immunother www.ncbi.nlm.nih.gov/pubmed/32123936 Genome-wide association study of genetic variations associated with treatment failure after intravesical bacillus Calmette-Guérin therapy for non-muscle invasive bladder cancer. treatment failure in response to intravesical BCG therapy in non-muscle invasive bladder cancer 44 Japanese ancestry individuals 47 Japanese ancestry individuals NR [657429] 0 response to BCG intravesical immunotherapy http://www.ebi.ac.uk/efo/EFO_0011041 GCST011697 Genome-wide genotyping array 44 2020-06-03 32119686 Dahlin A 2020-03-02 PLoS One www.ncbi.nlm.nih.gov/pubmed/32119686 Genome-wide interaction study reveals age-dependent determinants of responsiveness to inhaled corticosteroids in individuals with asthma. Adverse response to inhaled corticosteroid treatment x age interaction in asthma 407 European ancestry cases, 376 European ancestry controls 287 European ancestry cases, 251 European ancestry controls Affymetrix, Illumina [8589102] (imputed) 17 response to corticosteroid, age at assessment http://purl.obolibrary.org/obo/GO_0031960, http://www.ebi.ac.uk/efo/EFO_0008007 GCST010039 Genome-wide genotyping array 783 2020-05-29 32126890 Ter Hark SE 2020-03-04 J Psychopharmacol www.ncbi.nlm.nih.gov/pubmed/32126890 A new genetic locus for antipsychotic-induced weight gain: A genome-wide study of first-episode psychosis patients using amisulpride (from the OPTiMiSE cohort). Weight gain in amisulpride-treated first-episode psychosis 184 European ancestry individuals, 9 African ancestry individuals, 6 Hispanic/Latin American individuals, 3 South Asian ancestry individuals, 2 East Asian ancestry individuals, 2 individuals NA Illumina [4533042] (imputed) 21 longitudinal BMI measurement, response to amisulpride http://www.ebi.ac.uk/efo/EFO_0005937, http://www.ebi.ac.uk/efo/EFO_0010718 GCST010007 Genome-wide genotyping array 206 2020-07-09 32118827 Bonde A 2020-02-28 J Trauma Acute Care Surg www.ncbi.nlm.nih.gov/pubmed/32118827 Identification of a new genetic variant associated with cholecystitis: a multicenter genome-wide association study. Acute cholecystitis 900 European ancestry cases, 23,727 European ancestry controls NA Illumina [NR] (imputed) 1 Cholecystitis, Acute http://www.ebi.ac.uk/efo/EFO_1001289 GCST010176 Genome-wide genotyping array 24627 2020-07-09 32118827 Bonde A 2020-02-28 J Trauma Acute Care Surg www.ncbi.nlm.nih.gov/pubmed/32118827 Identification of a new genetic variant associated with cholecystitis: a multicenter genome-wide association study. Cholelithiasis up to 2,377 European ancestry cases, 22,203 European ancestry controls NA Illumina [NR] (imputed) 0 cholelithiasis http://www.ebi.ac.uk/efo/EFO_0004799 GCST010177 Genome-wide genotyping array 24580 2020-07-09 32117412 Boua PR 2020-02-07 Front Genet www.ncbi.nlm.nih.gov/pubmed/32117412 Novel and Known Gene-Smoking Interactions With cIMT Identified as Potential Drivers for Atherosclerosis Risk in West-African Populations of the AWI-Gen Study. Carotid intima media thickness x smoking interaction 465 West African ancestry male smokers, 1,311 West African ancestry male non-smokers NA Illumina [7839440] (imputed) 32 smoking status measurement, carotid artery intima media thickness http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0007117 GCST010151 Genome-wide genotyping array 1776 2020-07-22 32279069 Rovira P 2020-04-12 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/32279069 Shared genetic background between children and adults with attention deficit/hyperactivity disorder. Attention deficit hyperactivity disorder 17,149 European ancestry cases, 32,411 European ancestry controls NA Illumina [~ 1092418] (imputed) 7 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST010291 Genome-wide genotyping array 49560 2020-07-22 32279069 Rovira P 2020-04-12 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/32279069 Shared genetic background between children and adults with attention deficit/hyperactivity disorder. Attention deficit hyperactivity disorder (persistent) 6,532 European ancestry cases, 15,874 European ancestry controls NA Illumina [~ 1113287] (imputed) 25 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST010290 Genome-wide genotyping array 22406 2020-07-22 32279069 Rovira P 2020-04-12 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/32279069 Shared genetic background between children and adults with attention deficit/hyperactivity disorder. Attention deficit hyperactivity disorder (childhood) 10,617 European ancestry cases, 16,537 European ancestry controls NA Illumina [~ 1072558] (imputed) 10 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST010289 Genome-wide genotyping array 27154 2020-07-10 32121467 Adewuyi EO 2020-02-29 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/32121467 Shared Molecular Genetic Mechanisms Underlie Endometriosis and Migraine Comorbidity. Endometriosis or migraine 17,054 European and Japanese ancestry endometriosis cases, 29,208 European ancestry migraine cases, 191,858 European and Japanese ancestry controls, 172,931 European ancestry controls NA NR [6904914] (imputed) 47 endometriosis, migraine disorder http://www.ebi.ac.uk/efo/EFO_0001065, http://www.ebi.ac.uk/efo/EFO_0003821 GCST010178 Genome-wide genotyping array 411051 2020-06-12 26838040 Kristjansson RP 2016-02-03 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26838040 Common and rare variants associating with serum levels of creatine kinase and lactate dehydrogenase. Lactate dehydrogenase levels 98,585 Icelandic ancestry individuals NA Illumina [28300000] (imputed) 15 L lactate dehydrogenase measurement http://www.ebi.ac.uk/efo/EFO_0004808 GCST010069 Genome-wide genotyping array 98585 2020-06-12 26838040 Kristjansson RP 2016-02-03 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26838040 Common and rare variants associating with serum levels of creatine kinase and lactate dehydrogenase. Creatine kinase levels 63,159 Icelandic ancestry individuals NA Illumina [28300000] (imputed) 11 creatine kinase measurement http://www.ebi.ac.uk/efo/EFO_0004534 GCST010070 Genome-wide genotyping array 63159 2020-06-12 26838040 Kristjansson RP 2016-02-03 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26838040 Common and rare variants associating with serum levels of creatine kinase and lactate dehydrogenase. Creatine kinase levels in statin users 5,207 Icelandic ancestry individuals NA Illumina [28300000] (imputed) 3 creatine kinase measurement http://www.ebi.ac.uk/efo/EFO_0004534 GCST010068 Genome-wide genotyping array 5207 2020-06-12 26838040 Kristjansson RP 2016-02-03 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26838040 Common and rare variants associating with serum levels of creatine kinase and lactate dehydrogenase. Creatine kinase levels in off-statin users 6,877 Icelandic ancestry individuals NA Illumina [28300000] (imputed) 3 creatine kinase measurement http://www.ebi.ac.uk/efo/EFO_0004534 GCST010067 Genome-wide genotyping array 6877 2020-06-12 26838040 Kristjansson RP 2016-02-03 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26838040 Common and rare variants associating with serum levels of creatine kinase and lactate dehydrogenase. Lactate dehydrogenase levels in statin users 6,266 Icelandic ancestry individuals NA Illumina [28300000] (imputed) 2 L lactate dehydrogenase measurement http://www.ebi.ac.uk/efo/EFO_0004808 GCST010066 Genome-wide genotyping array 6266 2020-06-12 26838040 Kristjansson RP 2016-02-03 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26838040 Common and rare variants associating with serum levels of creatine kinase and lactate dehydrogenase. Lactate dehydrogenase levels in off-statin users 6,877 Icelandic ancestry individuals NA Illumina [28300000] (imputed) 5 L lactate dehydrogenase measurement http://www.ebi.ac.uk/efo/EFO_0004808 GCST010065 Genome-wide genotyping array 6877 2020-04-29 26690388 Tang CS 2015-12-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26690388 Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese. LDL cholesterol levels 12,685 Chinese ancestry individuals NA Illumina [286795] 5 LDL cholesterol change measurement http://www.ebi.ac.uk/efo/EFO_0007804 GCST009917 Exome genotyping array [Exome array] 12685 2020-04-29 26690388 Tang CS 2015-12-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26690388 Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese. HDL cholesterol levels 12,685 Chinese ancestry individuals NA Illumina [286795] 7 HDL cholesterol change measurement http://www.ebi.ac.uk/efo/EFO_0007805 GCST009918 Exome genotyping array [Exome array] 12685 2020-04-29 26690388 Tang CS 2015-12-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26690388 Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese. Total cholesterol levels 12,685 Chinese ancestry individuals NA Illumina [286795] 5 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST009919 Exome genotyping array [Exome array] 12685 2020-04-29 26690388 Tang CS 2015-12-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/26690388 Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese. Total triglycerides levels 12,685 Chinese ancestry individuals NA Illumina [286795] 7 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST009920 Exome genotyping array [Exome array] 12685 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Asthma 8,216 Japanese ancestry cases, 201,592 Japanese ancestry controls NA Illumina [8919992] (imputed) 13 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST90013679 Genome-wide genotyping array 209808 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Atopic dermatitis 2,385 Japanese ancestry cases, 209,651 Japanese ancestry controls NA Illumina [8919992] (imputed) 7 atopic eczema http://www.ebi.ac.uk/efo/EFO_0000274 GCST90013680 Genome-wide genotyping array 212036 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Drug eruption 430 Japanese ancestry cases, 209,651 Japanese ancestry controls NA Illumina [8919992] (imputed) 0 drug allergy http://www.ebi.ac.uk/efo/EFO_0009482 GCST90013681 Genome-wide genotyping array 210081 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Pollinosis 5,746 Japanese ancestry cases, 206,707 Japanese ancestry controls NA Illumina [8919992] (imputed) 0 seasonal allergic rhinitis http://www.ebi.ac.uk/efo/EFO_0003956 GCST90013682 Genome-wide genotyping array 212453 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Graves' disease 2,176 Japanese ancestry cases, 210,277 Japanese ancestry controls NA Illumina [8919992] (imputed) 11 Graves disease http://www.ebi.ac.uk/efo/EFO_0004237 GCST90013683 Genome-wide genotyping array 212453 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Rheumatoid arthritis 4,199 Japanese ancestry cases, 208,254 Japanese ancestry controls NA Illumina [8919992] (imputed) 6 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST90013684 Genome-wide genotyping array 212453 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Cerebral aneurysm 2,820 Japanese ancestry cases, 192,383 Japanese ancestry controls NA Illumina [8919992] (imputed) 5 brain aneurysm http://www.ebi.ac.uk/efo/EFO_0003870 GCST90013685 Genome-wide genotyping array 195203 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Congestive heart failure 9,413 Japanese ancestry cases, 203,040 Japanese ancestry controls NA Illumina [8919992] (imputed) 1 NA NA GCST90013686 Genome-wide genotyping array 212453 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Coronary artery disease 29,319 Japanese ancestry cases, 183,134 Japanese ancestry controls 2,855 Japanese ancestry cases, 15,211 Japanese ancestry controls Illumina [8919992] (imputed) 3 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST90013687 Genome-wide genotyping array 212453 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Ischemic stroke 17,671 Japanese ancestry cases, 192,383 Japanese ancestry controls NA Illumina [8919992] (imputed) 3 Ischemic stroke http://purl.obolibrary.org/obo/HP_0002140 GCST90013688 Genome-wide genotyping array 210054 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Peripheral artery disease 3,593 Japanese ancestry cases, 208,860 Japanese ancestry controls NA Illumina [8919992] (imputed) 3 peripheral arterial disease http://www.ebi.ac.uk/efo/EFO_0004265 GCST90013689 Genome-wide genotyping array 212453 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Chronic hepatitis B infection 1,394 Japanese ancestry cases, 211,059 Japanese ancestry controls NA Illumina [8919992] (imputed) 0 chronic hepatitis B virus infection http://www.ebi.ac.uk/efo/EFO_0004239 GCST90013690 Genome-wide genotyping array 212453 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Chronic hepatitis C infection 5,794 Japanese ancestry cases, 206,659 Japanese ancestry controls NA Illumina [8919992] (imputed) 1 chronic hepatitis C virus infection http://www.ebi.ac.uk/efo/EFO_0004220 GCST90013691 Genome-wide genotyping array 212453 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Pulmonary tuberculosis 549 Japanese ancestry cases, 211,904 Japanese ancestry controls NA Illumina [8919992] (imputed) 0 pulmonary tuberculosis http://www.ebi.ac.uk/efo/EFO_1000049 GCST90013692 Genome-wide genotyping array 212453 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Type 2 diabetes 40,250 Japanese ancestry cases, 170,615 Japanese ancestry controls NA Illumina [8919992] (imputed) 129 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST90013693 Genome-wide genotyping array 210865 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Biliary tract cancer 339 Japanese ancestry cases, 195,745 Japanese ancestry controls NA Illumina [8919992] (imputed) 0 biliary tract cancer http://purl.obolibrary.org/obo/MONDO_0003060 GCST90013694 Genome-wide genotyping array 196084 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Breast cancer 5,552 Japanese ancestry cases, 89,731 Japanese ancestry controls NA Illumina [8919992] (imputed) 9 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST90013695 Genome-wide genotyping array 95283 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Cervical cancer 605 Japanese ancestry cases, 89,731 Japanese ancestry controls NA Illumina [8919992] (imputed) 1 cervical carcinoma http://www.ebi.ac.uk/efo/EFO_0001061 GCST90013696 Genome-wide genotyping array 90336 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Colorectal cancer 7,062 Japanese ancestry cases, 195,745 Japanese ancestry controls NA Illumina [8919992] (imputed) 14 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST90013697 Genome-wide genotyping array 202807 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Endometrial cancer 999 Japanese ancestry cases, 89,731 Japanese ancestry controls NA Illumina [8919992] (imputed) 0 endometrial carcinoma http://www.ebi.ac.uk/efo/EFO_1001512 GCST90013698 Genome-wide genotyping array 90730 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Esophageal cancer 1,300 Japanese ancestry cases, 195,745 Japanese ancestry controls NA Illumina [8919992] (imputed) 2 esophageal carcinoma http://www.ebi.ac.uk/efo/EFO_0002916 GCST90013699 Genome-wide genotyping array 197045 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Gastric cancer 6,563 Japanese ancestry cases, 195,745 Japanese ancestry controls NA Illumina [8919992] (imputed) 5 gastric carcinoma http://www.ebi.ac.uk/efo/EFO_0000178 GCST90013700 Genome-wide genotyping array 202308 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Hematological malignancy 1,236 Japanese ancestry cases, 211,217 Japanese ancestry controls NA Illumina [8919992] (imputed) 0 hematopoietic and lymphoid system neoplasm http://purl.obolibrary.org/obo/MONDO_0002334 GCST90013701 Genome-wide genotyping array 212453 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Hepatocellular carcinoma 1,866 Japanese ancestry cases, 195,745 Japanese ancestry controls NA Illumina [8919992] (imputed) 1 hepatocellular carcinoma http://www.ebi.ac.uk/efo/EFO_0000182 GCST90013702 Genome-wide genotyping array 197611 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Lung cancer 4,050 Japanese ancestry cases, 208,403 Japanese ancestry controls 2,440 Japanese ancestry cases, 467 Japanese ancestry controls Illumina [8919992] (imputed) 1 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST90013703 Genome-wide genotyping array 212453 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Periodontal disease 1,415 Japanese ancestry male cases, 107,932 Japanese ancestry male controls NA Illumina [8919992] (imputed) 0 periodontitis http://www.ebi.ac.uk/efo/EFO_0000649 GCST90013754 Genome-wide genotyping array 109347 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Urolithiasis 4,996 Japanese ancestry male cases, 104,351 Japanese ancestry male controls NA Illumina [8919992] (imputed) 0 urolithiasis http://purl.obolibrary.org/obo/MONDO_0024647 GCST90013755 Genome-wide genotyping array 109347 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Asthma 4,284 Japanese ancestry female cases, 98,503 Japanese ancestry female controls NA Illumina [8919992] (imputed) 2 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST90013756 Genome-wide genotyping array 102787 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Atopic dermatitis 1,123 Japanese ancestry female cases, 101,789 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 atopic eczema http://www.ebi.ac.uk/efo/EFO_0000274 GCST90013757 Genome-wide genotyping array 102912 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Drug eruption 200 Japanese ancestry female cases, 101,789 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 drug allergy http://www.ebi.ac.uk/efo/EFO_0009482 GCST90013758 Genome-wide genotyping array 101989 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Pollinosis 3,286 Japanese ancestry female cases, 99,820 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 seasonal allergic rhinitis http://www.ebi.ac.uk/efo/EFO_0003956 GCST90013759 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Graves' disease 1,579 Japanese ancestry female cases, 101,527 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 Graves disease http://www.ebi.ac.uk/efo/EFO_0004237 GCST90013760 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Rheumatoid arthritis 3,325 Japanese ancestry female cases, 99,781 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST90013761 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Cerebral aneurysm 1,818 Japanese ancestry female cases, 94,928 Japanese ancestry female controls NA Illumina [8919992] (imputed) 1 brain aneurysm http://www.ebi.ac.uk/efo/EFO_0003870 GCST90013762 Genome-wide genotyping array 96746 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Congestive heart failure 3,509 Japanese ancestry female cases, 99,597 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 NA NA GCST90013763 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Coronary artery disease 7,708 Japanese ancestry female cases, 95,398 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST90013764 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Ischemic stroke 6,590 Japanese ancestry female cases, 94,928 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 Ischemic stroke http://purl.obolibrary.org/obo/HP_0002140 GCST90013765 Genome-wide genotyping array 101518 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Peripheral artery disease 809 Japanese ancestry female cases, 102,297 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 peripheral arterial disease http://www.ebi.ac.uk/efo/EFO_0004265 GCST90013766 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Chronic hepatitis B infection 516 Japanese ancestry female cases, 102,590 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 chronic hepatitis B virus infection http://www.ebi.ac.uk/efo/EFO_0004239 GCST90013767 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Chronic hepatitis C infection 2,635 Japanese ancestry female cases, 100,471 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 chronic hepatitis C virus infection http://www.ebi.ac.uk/efo/EFO_0004220 GCST90013768 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Pulmonary tuberculosis 162 Japanese ancestry female cases, 102,944 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 pulmonary tuberculosis http://www.ebi.ac.uk/efo/EFO_1000049 GCST90013769 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Type 2 diabetes 14,545 Japanese ancestry female cases, 87,841 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST90013770 Genome-wide genotyping array 102386 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Biliary tract cancer 128 Japanese ancestry female cases, 98,090 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 biliary tract cancer http://purl.obolibrary.org/obo/MONDO_0003060 GCST90013771 Genome-wide genotyping array 98218 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Colorectal cancer 2,566 Japanese ancestry female cases, 98,090 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST90013772 Genome-wide genotyping array 100656 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Esophageal cancer 168 Japanese ancestry female cases, 98,090 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 esophageal carcinoma http://www.ebi.ac.uk/efo/EFO_0002916 GCST90013773 Genome-wide genotyping array 98258 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Gastric cancer 1,678 Japanese ancestry female cases, 98,090 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 gastric carcinoma http://www.ebi.ac.uk/efo/EFO_0000178 GCST90013774 Genome-wide genotyping array 99768 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Hematological malignancy 535 Japanese ancestry female cases, 102,571 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 hematopoietic and lymphoid system neoplasm http://purl.obolibrary.org/obo/MONDO_0002334 GCST90013775 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Hepatocellular carcinoma 482 Japanese ancestry female cases, 98,090 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 hepatocellular carcinoma http://www.ebi.ac.uk/efo/EFO_0000182 GCST90013776 Genome-wide genotyping array 98572 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Lung cancer 1,340 Japanese ancestry female cases, 101,766 Japanese ancestry female controls NA Illumina [8919992] (imputed) 1 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST90013777 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Pancreatic cancer 154 Japanese ancestry female cases, 98,090 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 pancreatic carcinoma http://www.ebi.ac.uk/efo/EFO_0002618 GCST90013778 Genome-wide genotyping array 98244 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Arrhythmia 6,336 Japanese ancestry female cases, 96,770 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 cardiac arrhythmia http://www.ebi.ac.uk/efo/EFO_0004269 GCST90013779 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Cataracts 12,981 Japanese ancestry female cases, 90,125 Japanese ancestry female controls NA Illumina [8919992] (imputed) 1 cataract http://www.ebi.ac.uk/efo/EFO_0001059 GCST90013780 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Chronic obstructive pulmonary disease 460 Japanese ancestry female cases, 98,503 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 chronic obstructive pulmonary disease http://www.ebi.ac.uk/efo/EFO_0000341 GCST90013781 Genome-wide genotyping array 98963 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Cirrhosis 837 Japanese ancestry female cases, 102,269 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 cirrhosis of liver http://www.ebi.ac.uk/efo/EFO_0001422 GCST90013782 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Epilepsy 877 Japanese ancestry female cases, 102,229 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 epilepsy http://www.ebi.ac.uk/efo/EFO_0000474 GCST90013783 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Glaucoma 2,991 Japanese ancestry female cases, 100,115 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 glaucoma http://www.ebi.ac.uk/efo/EFO_0000516 GCST90013784 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Interstitial lung disease 311 Japanese ancestry female cases, 102,795 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 interstitial lung disease http://www.ebi.ac.uk/efo/EFO_0004244 GCST90013785 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Keloid 489 Japanese ancestry female cases, 102,617 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 Keloid http://www.ebi.ac.uk/efo/EFO_0004212 GCST90013786 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Nephrotic syndrome 374 Japanese ancestry female cases, 102,732 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 nephrotic syndrome http://www.ebi.ac.uk/efo/EFO_0004255 GCST90013787 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Osteoporosis 7,092 Japanese ancestry female cases, 96,014 Japanese ancestry female controls NA Illumina [8919992] (imputed) 1 osteoporosis http://www.ebi.ac.uk/efo/EFO_0003882 GCST90013788 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Periodontal disease 1,804 Japanese ancestry female cases, 101,302 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 periodontitis http://www.ebi.ac.uk/efo/EFO_0000649 GCST90013789 Genome-wide genotyping array 103106 2021-02-26 32514122 Ishigaki K 2020-06-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32514122 Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Urolithiasis 1,642 Japanese ancestry female cases, 101,464 Japanese ancestry female controls NA Illumina [8919992] (imputed) 0 urolithiasis http://purl.obolibrary.org/obo/MONDO_0024647 GCST90013790 Genome-wide genotyping array 103106 2020-09-03 32469254 Matsunaga H 2020-05-29 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/32469254 Transethnic Meta-analysis of Genome-wide Association Studies Identifies Three New Loci and Characterizes Population-specific Differences for Coronary Artery Disease. Coronary artery disease 15,302 Japanese ancestry cases, 36,140 Japanese ancestry controls NA Illumina [5932413] (imputed) 23 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST010480 Genome-wide genotyping array 51442 2020-09-03 32469254 Matsunaga H 2020-05-29 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/32469254 Transethnic Meta-analysis of Genome-wide Association Studies Identifies Three New Loci and Characterizes Population-specific Differences for Coronary Artery Disease. Coronary artery disease 15,302 Japanese ancestry cases, 76,014 European and East Asian ancestry cases, 36,140 Japanese ancestry controls, 264,785 European and East Asian ancestry controls NA Illumina [5167567] (imputed) 76 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST010479 Genome-wide genotyping array 392241 2020-07-06 31937794 Kim YW 2020-01-14 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31937794 Exploring the Novel Susceptibility Gene Variants for Primary Open-Angle Glaucoma in East Asian Cohorts: The GLAU-GENDISK Study. Glaucoma (primary open-angle) 309 Korean ancestry cases, 5,400 Korean ancestry controls 875 East Asian ancestry cases, 6,716 East Asian ancestry controls Illumina [63880] 1 open-angle glaucoma http://www.ebi.ac.uk/efo/EFO_0004190 GCST010119 Exome genotyping array [Exome array] 5709 2020-09-10 32492095 Zhou H 2020-06-03 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/32492095 Association of OPRM1 Functional Coding Variant With Opioid Use Disorder: A Genome-Wide Association Study. Opioid use disorder 10,544 European ancestry cases, 72,163 European ancestry controls, 5,212 African American cases, 26,876 African American controls 748 European ancestry cases, 361,107 European ancestry controls Affymetrix [9420000] (imputed) 1 opioid use disorder http://www.ebi.ac.uk/efo/EFO_0010702 GCST010510 Genome-wide genotyping array 114795 2019-12-03 31375628 Tengvall K 2019-08-02 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/31375628 Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple sclerosis risk. Anti-anoctamin 2 antibody levels 11,936 European ancestry individuals NA Illumina [615763] 10 anti-anoctamin 2 antibody measurement http://www.ebi.ac.uk/efo/EFO_0010150 GCST009154 Genome-wide genotyping array 11936 2021-03-30 32772156 Muntane G 2020-08-09 Hum Genet www.ncbi.nlm.nih.gov/pubmed/32772156 The shared genetic architecture of schizophrenia, bipolar disorder and lifespan. Schizophrenia or parental lifespan (pleiotropy) 40,675 European ancestry cases, 64,643 European ancestry controls, 450,000 European ancestry individuals NA NR [3206698] (imputed) 0 schizophrenia, parental longevity http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0007796 GCST011430 Genome-wide genotyping array 555318 2021-03-30 32772156 Muntane G 2020-08-09 Hum Genet www.ncbi.nlm.nih.gov/pubmed/32772156 The shared genetic architecture of schizophrenia, bipolar disorder and lifespan. Bipolar disorder or parental lifespan (pleiotropy) 20,352 European ancestry cases, 31,358 European ancestry controls, 450,000 European ancestry individuals NA NR [3206698] (imputed) 0 parental longevity, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0007796, http://www.ebi.ac.uk/efo/EFO_0000289 GCST011431 Genome-wide genotyping array 501710 2019-12-03 31371054 Ruddy KJ 2019-07-29 Fertil Steril www.ncbi.nlm.nih.gov/pubmed/31371054 Genetic predictors of chemotherapy-related amenorrhea in women with breast cancer. Adverse response to chemotherapy (amenorrhea) in breast cancer 457 European ancestry amenorrheic cases, 711 European ancestry post-chemotherapy menses cases NA Illumina [5430816] (imputed) 10 amenorrhea, response to antineoplastic agent http://www.ebi.ac.uk/efo/EFO_0010269, http://purl.obolibrary.org/obo/GO_0097327 GCST009153 Genome-wide genotyping array 1168 2021-02-26 33563987 Tyrrell J 2021-02-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33563987 Genetic predictors of participation in optional components of UK Biobank. Percentage of invited food questionnaires completed 300,639 European ancestry individuals NA Affymetrix [39302896] (imputed) 13 health study participation http://www.ebi.ac.uk/efo/EFO_0010130 GCST90012790 Genome-wide genotyping array 300639 2021-02-26 33563987 Tyrrell J 2021-02-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33563987 Genetic predictors of participation in optional components of UK Biobank. Acceptance of an invitation to wear a physical activity monitor 96,035 European ancestry cases, 119,092 European ancestry controls NA Affymetrix [39302896] (imputed) 2 health study participation http://www.ebi.ac.uk/efo/EFO_0010130 GCST90012791 Genome-wide genotyping array 215127 2021-02-26 33563987 Tyrrell J 2021-02-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33563987 Genetic predictors of participation in optional components of UK Biobank. Acceptance of an invitation to participate in a mental health questionnaire 146,074 European ancestry cases, 148,713 European ancestry controls NA Affymetrix [39302896] (imputed) 41 health study participation http://www.ebi.ac.uk/efo/EFO_0010130 GCST90012792 Genome-wide genotyping array 294787 2021-02-26 33563987 Tyrrell J 2021-02-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33563987 Genetic predictors of participation in optional components of UK Biobank. Completion of the aide-memoire 361,501 European ancestry cases, 89,535 European ancestry controls NA Affymetrix [39302896] (imputed) 5 health study participation http://www.ebi.ac.uk/efo/EFO_0010130 GCST90012793 Genome-wide genotyping array 451036 2021-02-26 33563987 Tyrrell J 2021-02-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33563987 Genetic predictors of participation in optional components of UK Biobank. Participation in an health questionnaire (not invited vs invited) 336,633 European ancestry cases, 114,464 European ancestry controls NA Affymetrix [39302896] (imputed) 36 health study participation http://www.ebi.ac.uk/efo/EFO_0010130 GCST90012794 Genome-wide genotyping array 451097 2019-09-05 30476138 Benonisdottir S 2019-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30476138 Sequence variants associating with urinary biomarkers. Urine specific gravity measurement 139,555 Icelandic ancestry individuals (includes non-array genotyped, whole-genome imputed individuals) NA Illumina [32500000] (imputed) 0 urine specific gravity measurement http://www.ebi.ac.uk/efo/EFO_0010135 GCST008604 Genome-wide genotyping array 139555 2019-09-05 30476138 Benonisdottir S 2019-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30476138 Sequence variants associating with urinary biomarkers. Glucosuria (moderate to severe) 6,109 Icelandic ancestry cases, 135,512 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals) NA Illumina [32500000] (imputed) 7 Glycosuria http://purl.obolibrary.org/obo/HP_0003076 GCST008605 Genome-wide genotyping array 141621 2019-09-05 30476138 Benonisdottir S 2019-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30476138 Sequence variants associating with urinary biomarkers. Glucosuria (mild) 4,748 Icelandic ancestry cases, 135,512 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals) NA Illumina [32500000] (imputed) 3 Glycosuria http://purl.obolibrary.org/obo/HP_0003076 GCST008606 Genome-wide genotyping array 140260 2019-09-05 30476138 Benonisdottir S 2019-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30476138 Sequence variants associating with urinary biomarkers. Ketonuria 41,130 Icelandic ancestry cases, 95,568 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals) NA Illumina [32500000] (imputed) 1 Ketonuria http://purl.obolibrary.org/obo/HP_0002919 GCST008607 Genome-wide genotyping array 136698 2019-09-05 30476138 Benonisdottir S 2019-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30476138 Sequence variants associating with urinary biomarkers. Ketonuria (moderate to severe) 21,803 Icelandic ancestry cases, 95,568 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals) NA Illumina [32500000] (imputed) 1 Ketonuria http://purl.obolibrary.org/obo/HP_0002919 GCST008608 Genome-wide genotyping array 117371 2019-09-05 30476138 Benonisdottir S 2019-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30476138 Sequence variants associating with urinary biomarkers. Ketonuria (mild) 19,327 Icelandic ancestry cases, 95,568 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals) NA Illumina [32500000] (imputed) 1 Ketonuria http://purl.obolibrary.org/obo/HP_0002919 GCST008609 Genome-wide genotyping array 114895 2019-09-05 30476138 Benonisdottir S 2019-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30476138 Sequence variants associating with urinary biomarkers. Proteinuria 54,009 Icelandic ancestry cases, 91,538 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals) NA Illumina [32500000] (imputed) 2 Proteinuria http://purl.obolibrary.org/obo/HP_0000093 GCST008610 Genome-wide genotyping array 145547 2019-09-05 30476138 Benonisdottir S 2019-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30476138 Sequence variants associating with urinary biomarkers. Proteinuria (moderate to severe) 25,317 Icelandic ancestry cases, 91,538 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals) NA Illumina [32500000] (imputed) 2 Proteinuria http://purl.obolibrary.org/obo/HP_0000093 GCST008611 Genome-wide genotyping array 116855 2019-09-05 30476138 Benonisdottir S 2019-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30476138 Sequence variants associating with urinary biomarkers. Proteinuria (mild) 28,692 Icelandic ancestry cases, 91,538 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals) NA Illumina [32500000] (imputed) 2 Proteinuria http://purl.obolibrary.org/obo/HP_0000093 GCST008612 Genome-wide genotyping array 120230 2019-09-05 30476138 Benonisdottir S 2019-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30476138 Sequence variants associating with urinary biomarkers. Hematuria 68,051 Icelandic ancestry cases, 68,903 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals) NA Illumina [32500000] (imputed) 4 Hematuria http://purl.obolibrary.org/obo/HP_0000790 GCST008613 Genome-wide genotyping array 136954 2019-09-05 30476138 Benonisdottir S 2019-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30476138 Sequence variants associating with urinary biomarkers. Hematuria (moderate to severe) 49,212 Icelandic ancestry cases, 68,903 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals) NA Illumina [32500000] (imputed) 4 Hematuria http://purl.obolibrary.org/obo/HP_0000790 GCST008617 Genome-wide genotyping array 118115 2019-09-05 30476138 Benonisdottir S 2019-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30476138 Sequence variants associating with urinary biomarkers. Hematuria (mild) 18,839 Icelandic ancestry cases, 68,903 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals) NA Illumina [32500000] (imputed) 2 Hematuria http://purl.obolibrary.org/obo/HP_0000790 GCST008618 Genome-wide genotyping array 87742 2019-09-05 30476138 Benonisdottir S 2019-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30476138 Sequence variants associating with urinary biomarkers. Urine pH measurement 149,899 Icelandic ancestry individuals (includes non-array genotyped, whole-genome imputed individuals) NA Illumina [32500000] (imputed) 4 urinary pH measurement http://www.ebi.ac.uk/efo/EFO_0010136 GCST008616 Genome-wide genotyping array 149899 2019-09-05 30476138 Benonisdottir S 2019-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30476138 Sequence variants associating with urinary biomarkers. Low urine pH 35,897 Icelandic ancestry cases, 112,302 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals) NA Illumina [32500000] (imputed) 4 urinary pH measurement http://www.ebi.ac.uk/efo/EFO_0010136 GCST008615 Genome-wide genotyping array 148199 2019-09-05 30476138 Benonisdottir S 2019-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30476138 Sequence variants associating with urinary biomarkers. Signs of urinary tract infection (nitrites and leukocyte esterase) 13,322 Icelandic ancestry cases, 66,528 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals) NA Illumina [32500000] (imputed) 0 leukocyte esterase measurement, nitrite measurement http://www.ebi.ac.uk/efo/EFO_0010137, http://www.ebi.ac.uk/efo/EFO_0010138 GCST008619 Genome-wide genotyping array 79850 2019-09-05 30476138 Benonisdottir S 2019-04-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30476138 Sequence variants associating with urinary biomarkers. Glucosuria 10,857 Icelandic ancestry cases, 135,512 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals) NA Illumina [32500000] (imputed) 8 Glycosuria http://purl.obolibrary.org/obo/HP_0003076 GCST008614 Genome-wide genotyping array 146369 2019-08-22 29237688 Weng LC 2017-12-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/29237688 Heritability of Atrial Fibrillation. Atrial fibrillation 2,987 European ancestry cases, 117,299 European ancestry controls NA Affymetrix [8325606] (imputed) 2 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST008486 Genome-wide genotyping array 120286 2021-03-22 32737115 Shirai Y 2020-07-31 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/32737115 Association of the RPA3-UMAD1 locus with interstitial lung diseases complicated with rheumatoid arthritis in Japanese. Interstitial lung diseases in rheumatoid arthritis 358 Japanese ancestry cases, 4,550 Japanese ancestry controls NA Illumina [5934489] (imputed) 11 interstitial lung disease http://www.ebi.ac.uk/efo/EFO_0004244 GCST011319 Genome-wide genotyping array 4908 2019-02-15 27818178 Hill WD 2016-11-03 Curr Biol www.ncbi.nlm.nih.gov/pubmed/27818178 Molecular Genetic Contributions to Social Deprivation and Household Income in UK Biobank. Household income 96,900 British ancestry individuals NA Affymetrix [~ 17300000] (imputed) 2 household income http://www.ebi.ac.uk/efo/EFO_0009695 GCST007155 Genome-wide genotyping array 96900 2019-02-15 27818178 Hill WD 2016-11-03 Curr Biol www.ncbi.nlm.nih.gov/pubmed/27818178 Molecular Genetic Contributions to Social Deprivation and Household Income in UK Biobank. Social deprivation 112,005 British ancestry individuals NA Affymetrix [~ 17300000] (imputed) 0 social deprivation http://www.ebi.ac.uk/efo/EFO_0009696 GCST007156 Genome-wide genotyping array 112005 2021-07-15 33545615 Hsu LA 2021-01-19 Atherosclerosis www.ncbi.nlm.nih.gov/pubmed/33545615 Circulating chemerin levels are determined through circulating platelet counts in nondiabetic Taiwanese people: A bidirectional Mendelian randomization study. Platelet count 17,037 Han Chinese ancestry individuals NA Affymetrix [603527] 11 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST012032 Genome-wide genotyping array 17037 2021-07-15 33545615 Hsu LA 2021-01-19 Atherosclerosis www.ncbi.nlm.nih.gov/pubmed/33545615 Circulating chemerin levels are determined through circulating platelet counts in nondiabetic Taiwanese people: A bidirectional Mendelian randomization study. Chemerin levels 3,887 Han Chinese ancestry individuals NA Affymetrix [610203] 2 chemerin measurement http://www.ebi.ac.uk/efo/EFO_0004573 GCST012031 Genome-wide genotyping array 3887 2021-01-26 32193507 Fan Q 2020-03-19 Commun Biol www.ncbi.nlm.nih.gov/pubmed/32193507 Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error. Corneal curvature 29,580 European ancestry individuals, 14,462 Asian ancestry individuals 88,218 European ancestry individuals Affymetrix, Illumina [8936601] (imputed) 41 corneal topography http://www.ebi.ac.uk/efo/EFO_0004345 GCST90012795 Genome-wide genotyping array 44042 2021-01-26 32193507 Fan Q 2020-03-19 Commun Biol www.ncbi.nlm.nih.gov/pubmed/32193507 Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error. Corneal curvature 29,580 European ancestry individuals NA Affymetrix, Illumina [8936601] (imputed) 32 corneal topography http://www.ebi.ac.uk/efo/EFO_0004345 GCST90012796 Genome-wide genotyping array 29580 2021-01-26 32193507 Fan Q 2020-03-19 Commun Biol www.ncbi.nlm.nih.gov/pubmed/32193507 Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error. Corneal curvature 14,462 Asian ancestry individuals NA Affymetrix, Illumina [7861976] (imputed) 11 corneal topography http://www.ebi.ac.uk/efo/EFO_0004345 GCST90012797 Genome-wide genotyping array 14462 2021-01-26 32193507 Fan Q 2020-03-19 Commun Biol www.ncbi.nlm.nih.gov/pubmed/32193507 Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error. Corneal curvature 8,620 individuals (<25 years old) NA Affymetrix, Illumina [8936601] (imputed) 6 corneal topography http://www.ebi.ac.uk/efo/EFO_0004345 GCST90012798 Genome-wide genotyping array 8645 2021-01-26 32193507 Fan Q 2020-03-19 Commun Biol www.ncbi.nlm.nih.gov/pubmed/32193507 Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error. Corneal curvature 35,422 individuals (>=25 years old) NA Affymetrix, Illumina [8936601] (imputed) 40 corneal topography http://www.ebi.ac.uk/efo/EFO_0004345 GCST90012799 Genome-wide genotyping array 35447 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota alpha diversity (Chao1 index) 541 Japanese ancestry women NA Illumina [545605] 3 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90007012 Genome-wide genotyping array 541 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota alpha diversity (Chao1 index) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 17 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST010819 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota alpha diversity (PD_whole_tree index) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 24 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST010818 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota alpha diversity (Shannon index) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 8 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST010817 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota beta diversity (weighted UniFrac distance) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 10 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST010816 Genome-wide genotyping array 1068 2019-08-02 31080455 Fatumo S 2019-04-26 Front Genet www.ncbi.nlm.nih.gov/pubmed/31080455 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits. Blood cell traits (multivariate analysis) up to 6,407 Sub-Saharan African ancestry individuals NA Illumina [20594536] (imputed) 8 lymphocyte count, mean platelet volume, leukocyte count, mean corpuscular volume, hematocrit, basophil count, platelet count, red blood cell distribution width, neutrophil count, hemoglobin measurement, erythrocyte count, mean corpuscular hemoglobin concentration, monocyte count, mean corpuscular hemoglobin, eosinophil count http://www.ebi.ac.uk/efo/EFO_0004587, http://www.ebi.ac.uk/efo/EFO_0004584, http://www.ebi.ac.uk/efo/EFO_0004308, http://www.ebi.ac.uk/efo/EFO_0004526, http://www.ebi.ac.uk/efo/EFO_0004348, http://www.ebi.ac.uk/efo/EFO_0005090, http://www.ebi.ac.uk/efo/EFO_0004309, http://www.ebi.ac.uk/efo/EFO_0005192, http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004509, http://www.ebi.ac.uk/efo/EFO_0004305, http://www.ebi.ac.uk/efo/EFO_0004528, http://www.ebi.ac.uk/efo/EFO_0005091, http://www.ebi.ac.uk/efo/EFO_0004527, http://www.ebi.ac.uk/efo/EFO_0004842 GCST008338 Genome-wide genotyping array, Genome-wide sequencing 6407 2019-08-02 31080455 Fatumo S 2019-04-26 Front Genet www.ncbi.nlm.nih.gov/pubmed/31080455 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits. White blood cell count 1,625 Sub-Saharan African ancestry individuals NA Illumina [20594536] (imputed) 0 leukocyte count http://www.ebi.ac.uk/efo/EFO_0004308 GCST008322 Genome-wide genotyping array, Genome-wide sequencing 1625 2019-08-02 31080455 Fatumo S 2019-04-26 Front Genet www.ncbi.nlm.nih.gov/pubmed/31080455 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits. Red blood cell count 1,625 Sub-Saharan African ancestry individuals NA Illumina [20594536] (imputed) 2 erythrocyte count http://www.ebi.ac.uk/efo/EFO_0004305 GCST008329 Genome-wide genotyping array, Genome-wide sequencing 1625 2019-08-02 31080455 Fatumo S 2019-04-26 Front Genet www.ncbi.nlm.nih.gov/pubmed/31080455 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits. Mean corpuscular volume 1,625 Sub-Saharan African ancestry individuals NA Illumina [20594536] (imputed) 1 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST008330 Genome-wide genotyping array, Genome-wide sequencing 1625 2019-08-02 31080455 Fatumo S 2019-04-26 Front Genet www.ncbi.nlm.nih.gov/pubmed/31080455 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits. Mean corpuscular hemoglobin 1,625 Sub-Saharan African ancestry individuals NA Illumina [20594536] (imputed) 1 mean corpuscular hemoglobin http://www.ebi.ac.uk/efo/EFO_0004527 GCST008331 Genome-wide genotyping array, Genome-wide sequencing 1625 2019-08-02 31080455 Fatumo S 2019-04-26 Front Genet www.ncbi.nlm.nih.gov/pubmed/31080455 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits. Mean corpuscular hemoglobin concentration 1,625 Sub-Saharan African ancestry individuals NA Illumina [20594536] (imputed) 1 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST008332 Genome-wide genotyping array, Genome-wide sequencing 1625 2019-08-02 31080455 Fatumo S 2019-04-26 Front Genet www.ncbi.nlm.nih.gov/pubmed/31080455 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits. Red cell distribution width 1,625 Sub-Saharan African ancestry individuals NA Illumina [20594536] (imputed) 1 red blood cell distribution width http://www.ebi.ac.uk/efo/EFO_0005192 GCST008333 Genome-wide genotyping array, Genome-wide sequencing 1625 2019-08-02 31080455 Fatumo S 2019-04-26 Front Genet www.ncbi.nlm.nih.gov/pubmed/31080455 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits. Hematocrit 1,625 Sub-Saharan African ancestry individuals NA Illumina [20594536] (imputed) 0 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST008323 Genome-wide genotyping array, Genome-wide sequencing 1625 2019-08-02 31080455 Fatumo S 2019-04-26 Front Genet www.ncbi.nlm.nih.gov/pubmed/31080455 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits. Hemoglobin 1,625 Sub-Saharan African ancestry individuals NA Illumina [20594536] (imputed) 0 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST008324 Genome-wide genotyping array, Genome-wide sequencing 1625 2019-08-02 31080455 Fatumo S 2019-04-26 Front Genet www.ncbi.nlm.nih.gov/pubmed/31080455 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits. Neutrophil count 1,415 Sub-Saharan African ancestry individuals NA Illumina [20594536] (imputed) 1 neutrophil count http://www.ebi.ac.uk/efo/EFO_0004833 GCST008334 Genome-wide genotyping array, Genome-wide sequencing 1415 2019-08-02 31080455 Fatumo S 2019-04-26 Front Genet www.ncbi.nlm.nih.gov/pubmed/31080455 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits. Platelet count 1,625 Sub-Saharan African ancestry individuals NA Illumina [20594536] (imputed) 0 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST008325 Genome-wide genotyping array, Genome-wide sequencing 1625 2019-08-02 31080455 Fatumo S 2019-04-26 Front Genet www.ncbi.nlm.nih.gov/pubmed/31080455 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits. Lymphocyte counts 1,565 Sub-Saharan African ancestry individuals NA Illumina [20594536] (imputed) 0 lymphocyte count http://www.ebi.ac.uk/efo/EFO_0004587 GCST008326 Genome-wide genotyping array, Genome-wide sequencing 1565 2019-08-02 31080455 Fatumo S 2019-04-26 Front Genet www.ncbi.nlm.nih.gov/pubmed/31080455 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits. Monocyte count 1,565 Sub-Saharan African ancestry individuals NA Illumina [20594536] (imputed) 0 monocyte count http://www.ebi.ac.uk/efo/EFO_0005091 GCST008327 Genome-wide genotyping array, Genome-wide sequencing 1565 2019-08-02 31080455 Fatumo S 2019-04-26 Front Genet www.ncbi.nlm.nih.gov/pubmed/31080455 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits. Basophil count 1,565 Sub-Saharan African ancestry individuals NA Illumina [20594536] (imputed) 0 basophil count http://www.ebi.ac.uk/efo/EFO_0005090 GCST008328 Genome-wide genotyping array, Genome-wide sequencing 1565 2019-08-02 31080455 Fatumo S 2019-04-26 Front Genet www.ncbi.nlm.nih.gov/pubmed/31080455 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits. Eosinophil counts 1,555 Sub-Saharan African ancestry individuals NA Illumina [20594536] (imputed) 2 eosinophil count http://www.ebi.ac.uk/efo/EFO_0004842 GCST008335 Genome-wide genotyping array, Genome-wide sequencing 1555 2019-08-02 31080455 Fatumo S 2019-04-26 Front Genet www.ncbi.nlm.nih.gov/pubmed/31080455 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits. Mean platelet volume 1,624 Sub-Saharan African ancestry individuals NA Illumina [20594536] (imputed) 2 mean platelet volume http://www.ebi.ac.uk/efo/EFO_0004584 GCST008336 Genome-wide genotyping array, Genome-wide sequencing 1624 2019-08-02 31080455 Fatumo S 2019-04-26 Front Genet www.ncbi.nlm.nih.gov/pubmed/31080455 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits. Blood cell traits (multivariate analysis) up to 6,407 Sub-Saharan African ancestry individuals NA Illumina [20594536] (imputed) 3 neutrophil count, mean platelet volume, leukocyte count, erythrocyte count, mean corpuscular hemoglobin concentration, mean corpuscular volume, monocyte count, basophil count, platelet count, red blood cell distribution width, eosinophil count http://www.ebi.ac.uk/efo/EFO_0004833, http://www.ebi.ac.uk/efo/EFO_0004584, http://www.ebi.ac.uk/efo/EFO_0004308, http://www.ebi.ac.uk/efo/EFO_0004305, http://www.ebi.ac.uk/efo/EFO_0004528, http://www.ebi.ac.uk/efo/EFO_0004526, http://www.ebi.ac.uk/efo/EFO_0005091, http://www.ebi.ac.uk/efo/EFO_0005090, http://www.ebi.ac.uk/efo/EFO_0004309, http://www.ebi.ac.uk/efo/EFO_0005192, http://www.ebi.ac.uk/efo/EFO_0004842 GCST008337 Genome-wide genotyping array, Genome-wide sequencing 6407 2021-04-21 32785646 Maguire S 2020-08-12 J Natl Cancer Inst www.ncbi.nlm.nih.gov/pubmed/32785646 Common susceptibility loci for male breast cancer. Breast cancer (male) 1,380 European ancestry cases, 3,620 European ancestry controls 810 European ancestry cases, 1,026 European ancestry controls Illumina [8074073] (imputed) 7 male breast carcinoma http://www.ebi.ac.uk/efo/EFO_0006861 GCST011526 Genome-wide genotyping array 5000 2021-02-19 33589840 Schwartzentruber J 2021-02-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33589840 Genome-wide meta-analysis, fine-mapping and integrative prioritization implicate new Alzheimer's disease risk genes. Alzheimer's disease or family history of Alzheimer's disease 472,868 European ancestry individuals NA NR [10687077] (imputed) 30 Alzheimer's disease, family history of Alzheimer’s disease http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0009268 GCST90012877 Genome-wide genotyping array 472868 2021-02-19 33589840 Schwartzentruber J 2021-02-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33589840 Genome-wide meta-analysis, fine-mapping and integrative prioritization implicate new Alzheimer's disease risk genes. Family history of Alzheimer's disease 408,942 European ancestry individuals NA NR [25643628] (imputed) 0 family history of Alzheimer’s disease http://www.ebi.ac.uk/efo/EFO_0009268 GCST90012878 Genome-wide genotyping array 408942 2021-02-26 32165298 You D 2020-03-09 Gene www.ncbi.nlm.nih.gov/pubmed/32165298 Identification of genetic features associated with fine particulate matter (PM2.5) modulated DNA damage using improved random forest analysis. Particulate matter induced DNA damage 307 Han Chinese ancestry individuals NA Illumina [130136] 0 DNA methylation http://purl.obolibrary.org/obo/GO_0006306 GCST011159 Exome genotyping array [Exome array] 307 2021-02-16 32671597 Streicher SA 2020-07-15 Hum Genet www.ncbi.nlm.nih.gov/pubmed/32671597 A pooled genome-wide association study identifies pancreatic cancer susceptibility loci on chromosome 19p12 and 19p13.3 in the full-Jewish population. Pancreatic cancer 604 Jewish cases, 2,332 Jewish controls NA Affymetrix, Illumina [1286673] (imputed) 2 pancreatic carcinoma http://www.ebi.ac.uk/efo/EFO_0002618 GCST011117 Genome-wide genotyping array 2936 2020-09-10 32742401 Parviainen R 2020-06-12 Exp Ther Med www.ncbi.nlm.nih.gov/pubmed/32742401 A single genetic locus associated with pediatric fractures: A genome-wide association study on 3,230 patients. Fractures (paediatric) 48 European ancestry cases, 3,182 European ancestry controls NA Illumina [3515000] (imputed) 7 bone fracture http://www.ebi.ac.uk/efo/EFO_0003931 GCST010516 Genome-wide genotyping array 3230 2021-02-25 32722627 Jin T 2020-07-26 Nutrients www.ncbi.nlm.nih.gov/pubmed/32722627 Interactions of Habitual Coffee Consumption by Genetic Polymorphisms with the Risk of Prediabetes and Type 2 Diabetes Combined. Coffee consumption 6,080 Korean ancestry cases, 1,788 Korean ancestry controls NA Affymetrix [352228] (imputed) 11 coffee consumption http://www.ebi.ac.uk/efo/EFO_0004330 GCST011158 Genome-wide genotyping array 7868 2021-03-22 32740585 Sood RF 2020-08-01 Plast Reconstr Surg www.ncbi.nlm.nih.gov/pubmed/32740585 Genetic Risk of Trigger Finger: Results of a Genomewide Association Study. Trigger finger 942 European ancestry cases, 24,472 European ancestry controls NA Illumina [7846471] (imputed) 3 stenosing tenosynovitis http://www.ebi.ac.uk/efo/EFO_0010822 GCST011318 Genome-wide genotyping array 25414 2021-03-22 32741009 Guenther F 2020-08-02 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/32741009 Chances and challenges of machine learning-based disease classification in genetic association studies illustrated on age-related macular degeneration. Age-related macular degeneration 3,544 European ancestry cases, 44,521 European ancestry controls NA Affymetrix [11567158] (imputed) 3 age-related macular degeneration http://www.ebi.ac.uk/efo/EFO_0001365 GCST011317 Genome-wide genotyping array 48065 2021-03-24 32723749 Kwon YC 2020-07-28 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/32723749 Genome-wide association study in a Korean population identifies six novel susceptibility loci for rheumatoid arthritis. Rheumatoid arthritis 4,068 Korean ancestry cases, 36,487 Korean ancestry controls NA Illumina [NR] (imputed) 19 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST011389 Genome-wide genotyping array 40555 2020-08-13 32737300 Sallah N 2020-07-31 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32737300 Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections. Anti-Epstein-Barr virus nuclear antigen (EBNA) IgG levels 4,365 Ugandan ancestry individuals 2,162 European ancestry individuals Illumina [14929118] (imputed) 3 Epstein Barr virus nuclear antigen 1 IgG measurement http://www.ebi.ac.uk/efo/EFO_0007790 GCST90000522 Genome-wide genotyping array 4365 2020-08-13 32737300 Sallah N 2020-07-31 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32737300 Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections. Anti-Epstein-Barr virus viral capsid antigen (VCA) IgG levels 4,365 Ugandan ancestry individuals NA Illumina [14929118] (imputed) 0 Epstein Barr viral capsid antigen IgG measurement http://www.ebi.ac.uk/efo/EFO_0009274 GCST90000523 Genome-wide genotyping array 4365 2020-08-13 32737300 Sallah N 2020-07-31 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32737300 Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections. Anti-Kaposi's sarcoma associated herpesvirus ORF73 IgG levels 4,365 Ugandan ancestry individuals NA Illumina [14929118] (imputed) 0 anti-Kaposi's sarcoma-associated herpesvirus antibody measurement http://www.ebi.ac.uk/efo/EFO_0010758 GCST90000524 Genome-wide genotyping array 4365 2020-08-13 32737300 Sallah N 2020-07-31 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32737300 Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections. Anti-Kaposi's sarcoma associated herpesvirus K10.5 IgG levels 4,365 Ugandan ancestry individuals NA Illumina [14929118] (imputed) 0 anti-Kaposi's sarcoma-associated herpesvirus antibody measurement http://www.ebi.ac.uk/efo/EFO_0010758 GCST90000525 Genome-wide genotyping array 4365 2020-08-13 32737300 Sallah N 2020-07-31 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32737300 Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections. Anti-Kaposi's sarcoma associated herpesvirus K8.1 IgG levels 4,365 Ugandan ancestry individuals NA Illumina [14929118] (imputed) 0 anti-Kaposi's sarcoma-associated herpesvirus antibody measurement http://www.ebi.ac.uk/efo/EFO_0010758 GCST90000526 Genome-wide genotyping array 4365 2021-02-23 32709000 Jeong H 2020-07-17 Nutrients www.ncbi.nlm.nih.gov/pubmed/32709000 Identifying Interactions between Dietary Sodium, Potassium, Sodium-Potassium Ratios, and FGF5 rs16998073 Variants and Their Associated Risk for Hypertension in Korean Adults. Hypertension 8,178 Korean ancestry cases, 9,558 Korean ancestry controls NA Affymetrix [NR] 23 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST011141 Genome-wide genotyping array 17736 2021-03-24 32716492 Simcoe MJ 2020-07-27 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/32716492 Genome-wide association study of corneal biomechanical properties identifies over 200 loci providing insight into the genetic aetiology of ocular diseases. Corneal hysteresis 106,041 European ancestry individuals 9,029 European ancestry individuals Affymetrix [12000000] (imputed) 11 corneal hysteresis http://www.ebi.ac.uk/efo/EFO_0010066 GCST011391 Genome-wide genotyping array 106041 2021-03-24 32716492 Simcoe MJ 2020-07-27 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/32716492 Genome-wide association study of corneal biomechanical properties identifies over 200 loci providing insight into the genetic aetiology of ocular diseases. Corneal resistance factor 106,030 European ancestry individuals 9,029 European ancestry individuals Affymetrix [12000000] (imputed) 13 corneal resistance factor http://www.ebi.ac.uk/efo/EFO_0010067 GCST011390 Genome-wide genotyping array 106030 2021-06-04 32970232 Zhang YX 2020-09-24 Mol Genet Genomics www.ncbi.nlm.nih.gov/pubmed/32970232 Three pleiotropic loci associated with bone mineral density and lean body mass. Bone mineral density or leg lean mass (pleiotropy) 9,618 European ancestry individuals, 1,539 Han Chinese ancestry individuals, 843 African American individuals, 445 Hispanic individuals up to 500,000 European ancestry individuals Affymetrix, Illumina [12061510] (imputed) 2 bone density, lean body mass http://www.ebi.ac.uk/efo/EFO_0003923, http://www.ebi.ac.uk/efo/EFO_0004995 GCST011788 Genome-wide genotyping array 12445 2021-06-04 32970232 Zhang YX 2020-09-24 Mol Genet Genomics www.ncbi.nlm.nih.gov/pubmed/32970232 Three pleiotropic loci associated with bone mineral density and lean body mass. Bone mineral density 9,618 European ancestry individuals, 1,539 Han Chinese ancestry individuals, 843 African American individuals, 445 Hispanic individuals up to 500,000 European ancestry individuals Affymetrix, Illumina [12061510] (imputed) 1 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST011789 Genome-wide genotyping array 12445 2021-06-04 32970232 Zhang YX 2020-09-24 Mol Genet Genomics www.ncbi.nlm.nih.gov/pubmed/32970232 Three pleiotropic loci associated with bone mineral density and lean body mass. Arm lean mass 9,618 European ancestry individuals, 1,539 Han Chinese ancestry individuals, 843 African American individuals, 445 Hispanic individuals up to 500,000 European ancestry individuals Affymetrix, Illumina [12061510] (imputed) 0 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST011790 Genome-wide genotyping array 12445 2021-06-04 32970232 Zhang YX 2020-09-24 Mol Genet Genomics www.ncbi.nlm.nih.gov/pubmed/32970232 Three pleiotropic loci associated with bone mineral density and lean body mass. Leg lean mass 9,618 European ancestry individuals, 1,539 Han Chinese ancestry individuals, 843 African American individuals, 445 Hispanic individuals up to 500,000 European ancestry individuals Affymetrix, Illumina [12061510] (imputed) 2 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST011792 Genome-wide genotyping array 12445 2021-06-04 32970232 Zhang YX 2020-09-24 Mol Genet Genomics www.ncbi.nlm.nih.gov/pubmed/32970232 Three pleiotropic loci associated with bone mineral density and lean body mass. Bone mineral density or leg lean mass (pleiotropy) 9,618 European ancestry individuals, 1,539 Han Chinese ancestry individuals, 843 African American individuals, 445 Hispanic individuals up to 500,000 European ancestry individuals Affymetrix, Illumina [12061510] (imputed) 0 bone density, lean body mass http://www.ebi.ac.uk/efo/EFO_0003923, http://www.ebi.ac.uk/efo/EFO_0004995 GCST011791 Genome-wide genotyping array 12445 2018-11-29 27864402 Harris SE 2017-06-01 Int J Epidemiol www.ncbi.nlm.nih.gov/pubmed/27864402 Molecular genetic contributions to self-rated health. Self-rated health 111,749 British ancestry individuals NA Affymetrix [~ 17300000] (imputed) 13 self rated health http://www.ebi.ac.uk/efo/EFO_0004778 GCST006620 Genome-wide genotyping array 111749 2020-07-07 32489964 Cresci S 2020-01-03 J Lipid Atheroscler www.ncbi.nlm.nih.gov/pubmed/32489964 Genetic Architecture of Circulating Very-Long-Chain (C24:0 and C22:0) Ceramide Concentrations. Ceramide levels (C24:0) 2,217 European ancestry individuals NA Affymetrix [9346801] (imputed) 14 ceramide measurement http://www.ebi.ac.uk/efo/EFO_0010222 GCST010121 Genome-wide genotyping array 2217 2020-07-07 32489964 Cresci S 2020-01-03 J Lipid Atheroscler www.ncbi.nlm.nih.gov/pubmed/32489964 Genetic Architecture of Circulating Very-Long-Chain (C24:0 and C22:0) Ceramide Concentrations. Ceramide levels (C22:0) 2,217 European ancestry individuals NA Affymetrix [9346801] (imputed) 7 ceramide measurement http://www.ebi.ac.uk/efo/EFO_0010222 GCST010122 Genome-wide genotyping array 2217 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Carboplatin drug response (IC50) 168 European ancestry individuals NA NR [6315985] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011787 Genome-wide genotyping array, Genome-wide sequencing 168 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Ara-C drug response (AUC) 432 East Asian, European and African ancestry individuals NA NR [3799865] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011773 Genome-wide genotyping array, Genome-wide sequencing 432 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Capecitabine drug response (AUC) 424 East Asian, European and African ancestry individuals NA NR [3799863] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011774 Genome-wide genotyping array, Genome-wide sequencing 424 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Carboplatin drug response (IC50) 430 East Asian, European and African ancestry individuals NA NR [3799860] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011775 Genome-wide genotyping array, Genome-wide sequencing 430 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Cisplatin drug response (IC50) 431 East Asian, European and African ancestry individuals NA NR [3799860] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011776 Genome-wide genotyping array, Genome-wide sequencing 431 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Daunorubicin drug response (IC50) 259 European and African ancestry individuals NA NR [3798360] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011777 Genome-wide genotyping array, Genome-wide sequencing 259 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Etoposide drug response (IC50) 255 European and African ancestry individuals NA NR [3798298] (imputed) 1 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011778 Genome-wide genotyping array, Genome-wide sequencing 255 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Paclitaxel drug response (AUC) 164 European and African ancestry individuals NA NR [3796783] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011779 Genome-wide genotyping array, Genome-wide sequencing 164 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Pemetrexed drug response (AUC) 260 European and African ancestry individuals NA NR [3798359] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011780 Genome-wide genotyping array, Genome-wide sequencing 260 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Ara-C drug response (AUC) 90 East Asian ancestry individuals NA NR [5206187] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011781 Genome-wide genotyping array, Genome-wide sequencing 90 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Capecitabine drug response (AUC) 84 East Asian ancestry individuals NA NR [5200691] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011782 Genome-wide genotyping array, Genome-wide sequencing 84 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Carboplatin drug response (IC50) 90 East Asian ancestry individuals NA NR [5206187] (imputed) 1 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011783 Genome-wide genotyping array, Genome-wide sequencing 90 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Cisplatin drug response (IC50) 90 East Asian ancestry individuals NA NR [5206187] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011784 Genome-wide genotyping array, Genome-wide sequencing 90 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Ara-C drug response (AUC) 165 European ancestry individuals NA NR [6310542] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011785 Genome-wide genotyping array, Genome-wide sequencing 165 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Capecitabine drug response (AUC) 165 European ancestry individuals NA NR [6311590] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011786 Genome-wide genotyping array, Genome-wide sequencing 165 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Cisplatin drug response (IC50) 166 European ancestry individuals NA NR [6312355] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011788 Genome-wide genotyping array, Genome-wide sequencing 166 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Daunorubicin drug response (IC50) 86 European ancestry individuals NA NR [6263189] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011789 Genome-wide genotyping array, Genome-wide sequencing 86 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Etoposide drug response (IC50) 84 European ancestry individuals NA NR [6255207] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011790 Genome-wide genotyping array, Genome-wide sequencing 84 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Paclitaxel drug response (AUC) 77 European ancestry individuals NA NR [6223077] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011791 Genome-wide genotyping array, Genome-wide sequencing 77 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Pemetrexed drug response (AUC) 84 European ancestry individuals NA NR [6254701] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011792 Genome-wide genotyping array, Genome-wide sequencing 84 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Ara-C drug response (AUC) 177 African ancestry individuals NA NR [9548582] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011793 Genome-wide genotyping array, Genome-wide sequencing 177 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Capecitabine drug response (AUC) 175 African ancestry individuals NA NR [9542312] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011794 Genome-wide genotyping array, Genome-wide sequencing 175 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Carboplatin drug response (IC50) 172 African ancestry individuals NA NR [9531231] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011795 Genome-wide genotyping array, Genome-wide sequencing 172 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Cisplatin drug response (IC50) 175 African ancestry individuals NA NR [9542566] (imputed) 1 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011796 Genome-wide genotyping array, Genome-wide sequencing 175 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Daunorubicin drug response (IC50) 173 African ancestry individuals NA NR [9536189] (imputed) 1 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011797 Genome-wide genotyping array, Genome-wide sequencing 173 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Etoposide drug response (IC50) 171 African ancestry individuals NA NR [9524322] (imputed) 1 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011798 Genome-wide genotyping array, Genome-wide sequencing 171 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Paclitaxel drug response (AUC) 87 African ancestry individuals NA NR [9364915] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011799 Genome-wide genotyping array, Genome-wide sequencing 87 2021-02-23 33575800 Mulford AJ 2021-02-11 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33575800 Genetically regulated expression underlies cellular sensitivity to chemotherapy in diverse populations. Pemetrexed drug response (AUC) 176 African ancestry individuals NA NR [9545800] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90011800 Genome-wide genotyping array, Genome-wide sequencing 176 2021-01-27 32386320 Eckel-Passow JE 2020-05-09 Neuro Oncol www.ncbi.nlm.nih.gov/pubmed/32386320 Adult Diffuse Glioma GWAS by Molecular Subtype Identifies Variants in D2HGDH and FAM20C. Adult diffuse glioma (IDH mutation) 622 European and unknown ancestry cases, 1,889 European and unknown ancestry controls 390 European and unknown ancestry cases, 808 European and unknown ancestry controls Illumina [NR] (imputed) 8 glioma http://www.ebi.ac.uk/efo/EFO_0005543 GCST011004 Genome-wide genotyping array 2511 2021-01-27 32386320 Eckel-Passow JE 2020-05-09 Neuro Oncol www.ncbi.nlm.nih.gov/pubmed/32386320 Adult Diffuse Glioma GWAS by Molecular Subtype Identifies Variants in D2HGDH and FAM20C. Adult diffuse glioma (IDH wildtype) 698 European and unknown ancestry cases, 1,889 European and unknown ancestry controls 409 European and unknown ancestry cases, 808 European and unknown ancestry controls Illumina [NR] (imputed) 2 glioma http://www.ebi.ac.uk/efo/EFO_0005543 GCST011003 Genome-wide genotyping array 2587 2021-01-27 32386320 Eckel-Passow JE 2020-05-09 Neuro Oncol www.ncbi.nlm.nih.gov/pubmed/32386320 Adult Diffuse Glioma GWAS by Molecular Subtype Identifies Variants in D2HGDH and FAM20C. Adult diffuse glioma (IDH mutation, 1p/19q codeletion) 245 European and unknown ancestry cases, 1,889 European and unknown ancestry controls 145 European and unknown ancestry cases, 808 European and unknown ancestry controls Illumina [NR] (imputed) 2 glioma http://www.ebi.ac.uk/efo/EFO_0005543 GCST011002 Genome-wide genotyping array 2134 2021-01-27 32386320 Eckel-Passow JE 2020-05-09 Neuro Oncol www.ncbi.nlm.nih.gov/pubmed/32386320 Adult Diffuse Glioma GWAS by Molecular Subtype Identifies Variants in D2HGDH and FAM20C. Adult diffuse glioma (IDH mutation, 1p/19q non-codeleted) 316 European and unknown ancestry cases, 1,889 European and unknown ancestry controls 245 European and unknown ancestry cases, 808 European and unknown ancestry controls Illumina [NR] (imputed) 4 glioma http://www.ebi.ac.uk/efo/EFO_0005543 GCST011001 Genome-wide genotyping array 2205 2021-01-27 32386320 Eckel-Passow JE 2020-05-09 Neuro Oncol www.ncbi.nlm.nih.gov/pubmed/32386320 Adult Diffuse Glioma GWAS by Molecular Subtype Identifies Variants in D2HGDH and FAM20C. Adult diffuse triple positive glioma (IDH and TERT mutations, 1p19q codeletion) 189 European and unknown ancestry cases, 1,889 European and unknown ancestry controls 138 European and unknown ancestry cases, 808 European and unknown ancestry controls Illumina [NR] (imputed) 3 glioma http://www.ebi.ac.uk/efo/EFO_0005543 GCST011000 Genome-wide genotyping array 2078 2021-01-27 32386320 Eckel-Passow JE 2020-05-09 Neuro Oncol www.ncbi.nlm.nih.gov/pubmed/32386320 Adult Diffuse Glioma GWAS by Molecular Subtype Identifies Variants in D2HGDH and FAM20C. Adult diffuse glioma (IDH and TERT mutations) 39 European and unknown ancestry cases, 1,889 European and unknown ancestry controls 13 European and unknown ancestry cases, 808 European and unknown ancestry controls Illumina [NR] (imputed) 0 glioma http://www.ebi.ac.uk/efo/EFO_0005543 GCST010999 Genome-wide genotyping array 1928 2021-01-27 32386320 Eckel-Passow JE 2020-05-09 Neuro Oncol www.ncbi.nlm.nih.gov/pubmed/32386320 Adult Diffuse Glioma GWAS by Molecular Subtype Identifies Variants in D2HGDH and FAM20C. Adult diffuse glioma (IDH mutation only) 241 European and unknown ancestry cases, 1,889 European and unknown ancestry controls 214 European and unknown ancestry cases, 808 European and unknown ancestry controls Illumina [NR] (imputed) 2 glioma http://www.ebi.ac.uk/efo/EFO_0005543 GCST010998 Genome-wide genotyping array 2130 2021-01-27 32386320 Eckel-Passow JE 2020-05-09 Neuro Oncol www.ncbi.nlm.nih.gov/pubmed/32386320 Adult Diffuse Glioma GWAS by Molecular Subtype Identifies Variants in D2HGDH and FAM20C. Adult diffuse glioma (TERT mutation only) 419 European and unknown ancestry cases, 1,889 European and unknown ancestry controls 159 European and unknown ancestry cases, 808 European and unknown ancestry controls Illumina [NR] (imputed) 2 glioma http://www.ebi.ac.uk/efo/EFO_0005543 GCST010997 Genome-wide genotyping array 2308 2021-01-27 32386320 Eckel-Passow JE 2020-05-09 Neuro Oncol www.ncbi.nlm.nih.gov/pubmed/32386320 Adult Diffuse Glioma GWAS by Molecular Subtype Identifies Variants in D2HGDH and FAM20C. Adult diffuse triple negative glioma (IDH and TERT wildtype, 1p/19q non-codeleted) 87 European and unknown ancestry cases, 1,889 European and unknown ancestry controls 33 European and unknown ancestry cases, 808 European and unknown ancestry controls Illumina [NR] (imputed) 0 glioma http://www.ebi.ac.uk/efo/EFO_0005543 GCST010996 Genome-wide genotyping array 1976 2021-05-04 32963231 Hofer E 2020-09-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32963231 Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. Cortical surface area 18,617 European and African American ancestry individuals 22,363 European ancestry individuals Affymetrix, Illumina [NR] (imputed) 41 cortical surface area measurement http://www.ebi.ac.uk/efo/EFO_0010736 GCST011617 Genome-wide genotyping array 18617 2021-05-04 32963231 Hofer E 2020-09-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32963231 Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. Cortical volume 22,824 European and African American ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 62 brain volume measurement http://www.ebi.ac.uk/efo/EFO_0006930 GCST011616 Genome-wide genotyping array 22824 2021-05-04 32963231 Hofer E 2020-09-22 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32963231 Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. Cortical thickness 22,163 European and African American ancestry individuals 22,363 European ancestry individuals Affymetrix, Illumina [NR] (imputed) 12 cortical thickness http://www.ebi.ac.uk/efo/EFO_0004840 GCST011618 Genome-wide genotyping array 22163 2020-08-22 32794382 Cho SB 2020-07-28 Diabetes Metab J www.ncbi.nlm.nih.gov/pubmed/32794382 Exome Chip Analysis of 14,026 Koreans Reve-als Known and Newly Discovered Genetic Loci Associated with Type 2 Diabetes Mellitus. Type 2 diabetes 14,026 Korean ancestry individuals NA Illumina [up to 242901] 7 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST010436 Exome genotyping array [Exome array] 14026 2019-08-23 31358989 Gelernter J 2019-07-29 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/31358989 Genome-wide association study of post-traumatic stress disorder reexperiencing symptoms in >165,000 US veterans. Post-traumatic stress disorder (re-experiencing symptoms) 146,660 European ancestry individuals, 19,983 African American individuals 117,900 European ancestry individuals Affymetrix [49134253] (imputed) 16 post-traumatic stress disorder symptom measurement http://www.ebi.ac.uk/efo/EFO_0008535 GCST008490 Genome-wide genotyping array 166643 2019-08-27 28972577 Hancock DB 2017-10-03 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/28972577 Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence. Nicotine dependence 28,677 European ancestry individuals, 9,925 African American individuals NA Affymetrix, Illumina [~ 18000000] (imputed) 6 nicotine dependence http://www.ebi.ac.uk/efo/EFO_0003768 GCST008496 Genome-wide genotyping array 38602 2019-09-13 28067910 Luo Y 2017-01-09 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28067910 Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7. Ulcerative colitis 7,760 European ancestry cases, 16,065 European ancestry controls 5,054 European ancestry cases, 450 cases, 162,024 European ancestry controls, 3,905 controls Affymetrix, Illumina [~ 12000000] (imputed) 1 ulcerative colitis http://www.ebi.ac.uk/efo/EFO_0000729 GCST008658 Genome-wide genotyping array, Genome-wide sequencing 23825 2021-08-13 33539483 Li Z 2021-02-04 PLoS One www.ncbi.nlm.nih.gov/pubmed/33539483 Bivariate genome-wide association study (GWAS) of body mass index and blood pressure phenotypes in northern Chinese twins. Body mass index and systolic blood pressure (bivariate analysis) 274 Chinese ancestry dizygotic twins NA Illumina [7401356] (imputed) 13 systolic blood pressure, body mass index http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004340 GCST012191 Genome-wide genotyping array 274 2021-08-13 33539483 Li Z 2021-02-04 PLoS One www.ncbi.nlm.nih.gov/pubmed/33539483 Bivariate genome-wide association study (GWAS) of body mass index and blood pressure phenotypes in northern Chinese twins. Body mass index and diastolic blood pressure (bivariate analysis) 274 Chinese ancestry dizygotic twins NA Illumina [7401356] (imputed) 13 diastolic blood pressure, body mass index http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004340 GCST012190 Genome-wide genotyping array 274 2021-08-13 33539483 Li Z 2021-02-04 PLoS One www.ncbi.nlm.nih.gov/pubmed/33539483 Bivariate genome-wide association study (GWAS) of body mass index and blood pressure phenotypes in northern Chinese twins. Systolic blood pressure and diastolic blood pressure (bivariate analysis) 274 Chinese ancestry dizygotic twins NA Illumina [7401356] (imputed) 17 diastolic blood pressure, systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0006335 GCST012189 Genome-wide genotyping array 274 2021-08-13 33536081 Hu J 2021-02-03 Hum Genomics www.ncbi.nlm.nih.gov/pubmed/33536081 Genetic variants are identified to increase risk of COVID-19 related mortality from UK Biobank data. Mortality in COVID-19 292 European ancestry cases, 804 European ancestry controls NA NR [18617478] (imputed) 12 COVID-19, mortality http://purl.obolibrary.org/obo/MONDO_0100096, http://www.ebi.ac.uk/efo/EFO_0004352 GCST012192 Genome-wide genotyping array 1096 2020-11-04 32936915 Chai JF 2020-09-16 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/32936915 Genome-wide association for HbA1c in Malay identified deletion on SLC4A1 that influences HbA1c independent of glycemia. Glycated hemoglobin levels 1,721 Malay ancestry individuals NA Illumina [47095002] (imputed) 0 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST90011771 Genome-wide genotyping array 1721 2020-11-04 32936915 Chai JF 2020-09-16 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/32936915 Genome-wide association for HbA1c in Malay identified deletion on SLC4A1 that influences HbA1c independent of glycemia. Glycated hemoglobin levels 2,704 Malay ancestry individuals NA Illumina [47095002] (imputed) 4 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST90011772 Genome-wide genotyping array, Exome-wide sequencing 2704 2019-08-02 30894546 Ivarsdottir EV 2019-03-20 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30894546 Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density. Corneal hysteresis 6,125 Icelandic ancestry individuals NA Illumina [NR] 9 corneal hysteresis http://www.ebi.ac.uk/efo/EFO_0010066 GCST008315 Genome-wide genotyping array 6125 2019-08-02 30894546 Ivarsdottir EV 2019-03-20 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30894546 Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density. Corneal resistance factor 6,125 Icelandic ancestry individuals NA Illumina [NR] 9 corneal resistance factor http://www.ebi.ac.uk/efo/EFO_0010067 GCST008318 Genome-wide genotyping array 6125 2019-08-02 30894546 Ivarsdottir EV 2019-03-20 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30894546 Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density. Intraocular pressure (corneal compensated) 6,125 Icelandic ancestry individuals NA Illumina [NR] 1 intraocular pressure measurement http://www.ebi.ac.uk/efo/EFO_0004695 GCST008319 Genome-wide genotyping array 6125 2019-08-02 30894546 Ivarsdottir EV 2019-03-20 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30894546 Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density. Intraocular pressure (Goldman correlated) 6,125 Icelandic ancestry individuals NA Illumina [NR] 3 intraocular pressure measurement http://www.ebi.ac.uk/efo/EFO_0004695 GCST008320 Genome-wide genotyping array 6125 2019-08-02 30894546 Ivarsdottir EV 2019-03-20 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30894546 Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density. Central corneal thickness 6,125 Icelandic ancestry individuals 1,459 Icelandic ancestry individuals Illumina [NR] 11 central corneal thickness http://www.ebi.ac.uk/efo/EFO_0005213 GCST008317 Genome-wide genotyping array 6125 2019-08-02 30894546 Ivarsdottir EV 2019-03-20 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30894546 Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density. Corneal endothelial cell density 6,125 Icelandic ancestry individuals NA Illumina [NR] 58 corneal endothelial cell measurement http://www.ebi.ac.uk/efo/EFO_0010079 GCST008339 Genome-wide genotyping array 6125 2019-08-02 30894546 Ivarsdottir EV 2019-03-20 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30894546 Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density. Corneal endothelial cell size variation coefficient 6,125 Icelandic ancestry individuals NA Illumina [NR] 39 corneal endothelial cell measurement http://www.ebi.ac.uk/efo/EFO_0010079 GCST008316 Genome-wide genotyping array 6125 2019-08-02 30894546 Ivarsdottir EV 2019-03-20 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30894546 Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density. Corneal endothelial cell shape (percentage of hexagonally shaped cells) 6,125 Icelandic ancestry individuals NA Illumina [NR] 21 corneal endothelial cell measurement http://www.ebi.ac.uk/efo/EFO_0010079 GCST008321 Genome-wide genotyping array 6125 2020-07-16 31136621 van de Putte R 2019-05-28 PLoS One www.ncbi.nlm.nih.gov/pubmed/31136621 Exome chip association study excluded the involvement of rare coding variants with large effect sizes in the etiology of anorectal malformations. Anorectal malformation 568 European ancestry cases, 1,860 European ancestry controls NA Illumina [239042] 13 Anorectal malformation http://www.orpha.net/ORDO/Orphanet_96346 GCST010206 Exome genotyping array [Exome array] 2428 2019-01-25 30202859 Laisk T 2018-09-07 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30202859 Large scale meta-analysis highlights the hypothalamic-pituitary-gonadal (HPG) axis in the genetic regulation of menstrual cycle length. Length of menstrual cycle 44,871 European ancestry women NA Illumina [9344826] (imputed) 5 menstrual cycle measurement http://www.ebi.ac.uk/efo/EFO_0007786 GCST006958 Genome-wide genotyping array 44871 2021-03-22 33532862 Hartiala JA 2021-02-03 Eur Heart J www.ncbi.nlm.nih.gov/pubmed/33532862 Genome-wide analysis identifies novel susceptibility loci for myocardial infarction. Myocardial infarction 14,825 European ancestry cases, 44,000 European and unknown ancestry cases, 2,680 cases, 380,970 European ancestry controls, 123,504 European and unknown ancestry controls, 73,242 controls NA NR [8126035] (imputed) 159 myocardial infarction http://www.ebi.ac.uk/efo/EFO_0000612 GCST011365 Genome-wide genotyping array 639221 2021-03-22 33532862 Hartiala JA 2021-02-03 Eur Heart J www.ncbi.nlm.nih.gov/pubmed/33532862 Genome-wide analysis identifies novel susceptibility loci for myocardial infarction. Myocardial infarction 14,825 European ancestry cases, 2,680 cases, 380,970 European ancestry controls, 73,242 controls NA NR [10903881] (imputed) 31 myocardial infarction http://www.ebi.ac.uk/efo/EFO_0000612 GCST011364 Genome-wide genotyping array 471717 2020-08-19 32493714 Klimentidis YC 2020-06-03 Diabetes www.ncbi.nlm.nih.gov/pubmed/32493714 Phenotypic and Genetic Characterization of Lower LDL-C and Increased Type-2 Diabetes Risk in the UK Biobank. Low density lipoprotein cholesterol levels 431,167 European ancestry individuals NA Affymetrix [15000001] 157 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST90002412 Genome-wide genotyping array 431167 2020-06-11 31591516 Ricano-Ponce I 2019-10-07 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31591516 Immunochip meta-analysis in European and Argentinian populations identifies two novel genetic loci associated with celiac disease. Celiac disease 12,567 European ancestry cases, 381 Hispanic cases, 14,013 European ancestry controls, 813 Hispanic controls NA Illumina [127855] 4 celiac disease http://www.ebi.ac.uk/efo/EFO_0001060 GCST010064 Targeted genotyping array [ImmunoChip] 27774 2021-01-27 32428537 Meguro A 2020-05-16 Ophthalmology www.ncbi.nlm.nih.gov/pubmed/32428537 Genome-wide association study in Asians identifies novel loci for high myopia and highlights a nervous system role in its pathogenesis. High myopia 1,632 Japanese ancestry cases, 1,586 Japanese ancestry controls 800 East Asian ancestry cases, 81 Singaporean ancestry cases, 5,169 East Asian ancestry controls, 4,777 Singaporean ancestry controls Affymetrix, Illumina [4996193] (imputed) 9 Myopia http://purl.obolibrary.org/obo/HP_0000545 GCST010994 Genome-wide genotyping array 3218 2019-08-07 31095341 Kerns SL 2019-05-16 J Natl Cancer Inst www.ncbi.nlm.nih.gov/pubmed/31095341 Radiogenomics Consortium Genome-Wide Association Study Meta-analysis of Late Toxicity after Prostate Cancer Radiotherapy. Toxicity response to radiotherapy in prostate cancer (rectal bleeding) (time to event) 3,379 European ancestry individuals NA Affymetrix, Illumina [~ 6000000] (imputed) 14 Hematochezia, response to radiation http://purl.obolibrary.org/obo/HP_0002573, http://purl.obolibrary.org/obo/GO_0009314 GCST008381 Genome-wide genotyping array 3379 2019-08-07 31095341 Kerns SL 2019-05-16 J Natl Cancer Inst www.ncbi.nlm.nih.gov/pubmed/31095341 Radiogenomics Consortium Genome-Wide Association Study Meta-analysis of Late Toxicity after Prostate Cancer Radiotherapy. Toxicity response to radiotherapy in prostate cancer (decreased urine stream) (time to event) 3,470 European ancestry individuals NR Affymetrix, Illumina [~ 6000000] (imputed) 12 response to radiation, Urinary retention http://purl.obolibrary.org/obo/GO_0009314, http://purl.obolibrary.org/obo/HP_0000016 GCST008378 Genome-wide genotyping array 3470 2019-08-07 31095341 Kerns SL 2019-05-16 J Natl Cancer Inst www.ncbi.nlm.nih.gov/pubmed/31095341 Radiogenomics Consortium Genome-Wide Association Study Meta-analysis of Late Toxicity after Prostate Cancer Radiotherapy. Toxicity response to radiotherapy in prostate cancer (hematuria) (time to event) 3,619 European ancestry individuals 538 Japanese ancestry individuals Affymetrix, Illumina [~ 6000000] (imputed) 16 response to radiation, Hematuria http://purl.obolibrary.org/obo/GO_0009314, http://purl.obolibrary.org/obo/HP_0000790 GCST008380 Genome-wide genotyping array 3619 2019-08-07 31095341 Kerns SL 2019-05-16 J Natl Cancer Inst www.ncbi.nlm.nih.gov/pubmed/31095341 Radiogenomics Consortium Genome-Wide Association Study Meta-analysis of Late Toxicity after Prostate Cancer Radiotherapy. Response to radiotherapy in prostate cancer (overall toxicity) 3,871 European ancestry individuals NA Affymetrix, Illumina [~ 6000000] (imputed) 3 response to radiation, adverse effect http://purl.obolibrary.org/obo/GO_0009314, http://www.ebi.ac.uk/efo/EFO_0009658 GCST008379 Genome-wide genotyping array 3871 2019-08-07 31095341 Kerns SL 2019-05-16 J Natl Cancer Inst www.ncbi.nlm.nih.gov/pubmed/31095341 Radiogenomics Consortium Genome-Wide Association Study Meta-analysis of Late Toxicity after Prostate Cancer Radiotherapy. Toxicity response to radiotherapy in prostate cancer (increased urinary frequency) (time to event) 3,782 European ancestry individuals NA Affymetrix, Illumina [~ 6000000] (imputed) 6 response to radiation, Abnormality of the urinary system http://purl.obolibrary.org/obo/GO_0009314, http://purl.obolibrary.org/obo/HP_0000079 GCST008382 Genome-wide genotyping array 3782 2020-06-19 23593153 Huertas-Vazquez A 2013-04-04 PLoS One www.ncbi.nlm.nih.gov/pubmed/23593153 Novel loci associated with increased risk of sudden cardiac death in the context of coronary artery disease. Sudden cardiac arrest in coronary artery disease 948 European ancestry cases, 3,050 European ancestry controls NA Illumina [119117] 2 sudden cardiac arrest http://www.ebi.ac.uk/efo/EFO_0004278 GCST010089 Targeted genotyping array [Metabochip] 3998 2021-03-22 33536631 Bell S 2021-02-03 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33536631 A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis. Iron status biomarkers (ferritin levels) 246,139 European ancestry individuals NA Affymetrix, Illumina [40000000] (imputed) 39 ferritin measurement http://www.ebi.ac.uk/efo/EFO_0004459 GCST011369 Genome-wide genotyping array 246139 2021-03-22 33536631 Bell S 2021-02-03 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33536631 A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis. Iron status biomarkers (total iron binding capacity) 135,430 European ancestry individuals NA Affymetrix, Illumina [40000000] (imputed) 14 total iron binding capacity http://www.ebi.ac.uk/efo/EFO_0006334 GCST011368 Genome-wide genotyping array 135430 2021-03-22 33536631 Bell S 2021-02-03 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33536631 A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis. Iron status biomarkers (iron levels) 163,511 European ancestry individuals NA Affymetrix, Illumina [40000000] (imputed) 13 serum iron measurement http://www.ebi.ac.uk/efo/EFO_0006332 GCST011367 Genome-wide genotyping array 163511 2021-03-22 33536631 Bell S 2021-02-03 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33536631 A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis. Iron status biomarkers (transferrin saturation) 131,471 European ancestry individuals NA Affymetrix, Illumina [40000000] (imputed) 9 transferrin saturation measurement http://www.ebi.ac.uk/efo/EFO_0006333 GCST011366 Genome-wide genotyping array 131471 2021-08-13 33531474 Burton CL 2021-02-02 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/33531474 Genome-wide association study of pediatric obsessive-compulsive traits: shared genetic risk between traits and disorder. Obsessive-compulsive traits 5,018 European ancestry children and adolescents NA Illumina [7870334] (imputed) 15 Obsessive-compulsive trait http://purl.obolibrary.org/obo/HP_0008770 GCST012194 Genome-wide genotyping array 5018 2021-08-13 33531474 Burton CL 2021-02-02 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/33531474 Genome-wide association study of pediatric obsessive-compulsive traits: shared genetic risk between traits and disorder. Obsessive-compulsive disorder 3,369 European ancestry cases, 8,611 European ancestry controls NA Illumina [NR] (imputed) 0 obsessive-compulsive disorder http://www.ebi.ac.uk/efo/EFO_0004242 GCST012193 Genome-wide genotyping array 11980 2020-12-10 32210231 Hollis B 2020-03-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32210231 Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan. Male puberty timing (early vs. average onset facial hair) 13,226 European ancestry early onset individuals, 161,175 European ancestry average onset individuals NA NR [7400000] (imputed) 32 puberty onset measurement http://www.ebi.ac.uk/efo/EFO_0005677 GCST90012084 Genome-wide genotyping array 174401 2020-12-10 32210231 Hollis B 2020-03-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32210231 Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan. Male puberty timing (late vs. average onset facial hair) 26,066 European ancestry late onset individuals, 161,175 European ancestry average onset individuals NA NR [7400000] (imputed) 41 puberty onset measurement http://www.ebi.ac.uk/efo/EFO_0005677 GCST90012085 Genome-wide genotyping array 187241 2020-12-10 32210231 Hollis B 2020-03-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32210231 Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan. Male puberty timing (early vs. average onset voice breaking) 8,245 European ancestry early onset individuals, 172,138 European ancestry average onset individuals NA NR [7400000] (imputed) 18 puberty onset measurement http://www.ebi.ac.uk/efo/EFO_0005677 GCST90012086 Genome-wide genotyping array 180383 2020-12-10 32210231 Hollis B 2020-03-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32210231 Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan. Male puberty timing (late vs. average onset voice breaking) 11,334 European ancestry late onset individuals, 172,138 European ancestry average onset individuals NA NR [7400000] (imputed) 21 puberty onset measurement http://www.ebi.ac.uk/efo/EFO_0005677 GCST90012087 Genome-wide genotyping array 183472 2020-12-10 32210231 Hollis B 2020-03-24 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32210231 Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan. Male puberty timing (age at voice breaking MTAG) 205,354 European ancestry individuals NA NR [7400000] (imputed) 76 puberty onset measurement http://www.ebi.ac.uk/efo/EFO_0005677 GCST90012088 Genome-wide genotyping array 205354 2019-09-05 31362332 Cheng Z 2019-07-30 Addict Biol www.ncbi.nlm.nih.gov/pubmed/31362332 Genome-wide scan identifies opioid overdose risk locus close to MCOLN1. Opioid overdose severity score 2,032 European ancestry individuals, 1,445 African American individuals NA Illumina [up to 10295719] (imputed) 6 opioid overdose severity measurement http://www.ebi.ac.uk/efo/EFO_0010140 GCST008596 Genome-wide genotyping array 3477 2021-02-08 31363184 Zhu Z 2019-07-30 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/31363184 Heritability of human visual contour integration-an integrated genomic study. Visual contour integration 1,931 East Asian ancestry individuals 688 East Asian ancestry individuals Illumina [at least 830937] (imputed) 0 visual perception measurement http://www.ebi.ac.uk/efo/EFO_0009700 GCST011099 Genome-wide genotyping array 1931 2019-03-25 30704525 Guyatt AL 2019-01-31 Hum Genomics www.ncbi.nlm.nih.gov/pubmed/30704525 A genome-wide association study of mitochondrial DNA copy number in two population-based cohorts. Mitochondrial DNA copy number (white blood cells) 1,333 males NA Illumina [7369986] (imputed) 2 mitochondrial DNA measurement http://www.ebi.ac.uk/efo/EFO_0006312 GCST007392 Genome-wide genotyping array 1333 2019-03-25 30704525 Guyatt AL 2019-01-31 Hum Genomics www.ncbi.nlm.nih.gov/pubmed/30704525 A genome-wide association study of mitochondrial DNA copy number in two population-based cohorts. Mitochondrial DNA copy number 3,647 European ancestry children NA Illumina [7410776] (imputed) 11 mitochondrial DNA measurement http://www.ebi.ac.uk/efo/EFO_0006312 GCST007393 Genome-wide genotyping array 3647 2019-03-25 30704525 Guyatt AL 2019-01-31 Hum Genomics www.ncbi.nlm.nih.gov/pubmed/30704525 A genome-wide association study of mitochondrial DNA copy number in two population-based cohorts. Mitochondrial DNA copy number 2,102 European ancestry neonates NA Illumina [7361275] (imputed) 2 mitochondrial DNA measurement http://www.ebi.ac.uk/efo/EFO_0006312 GCST007394 Genome-wide genotyping array 2102 2019-03-25 30704525 Guyatt AL 2019-01-31 Hum Genomics www.ncbi.nlm.nih.gov/pubmed/30704525 A genome-wide association study of mitochondrial DNA copy number in two population-based cohorts. Mitochondrial DNA copy number 5,461 European ancestry mothers NA Illumina [7360988] (imputed) 3 mitochondrial DNA measurement http://www.ebi.ac.uk/efo/EFO_0006312 GCST007395 Genome-wide genotyping array 5461 2019-03-25 30704525 Guyatt AL 2019-01-31 Hum Genomics www.ncbi.nlm.nih.gov/pubmed/30704525 A genome-wide association study of mitochondrial DNA copy number in two population-based cohorts. Mitochondrial DNA copy number (white blood cells) 3,405 European ancestry mothers NA Illumina [7360988] (imputed) 2 mitochondrial DNA measurement http://www.ebi.ac.uk/efo/EFO_0006312 GCST007396 Genome-wide genotyping array 3405 2019-03-25 30704525 Guyatt AL 2019-01-31 Hum Genomics www.ncbi.nlm.nih.gov/pubmed/30704525 A genome-wide association study of mitochondrial DNA copy number in two population-based cohorts. Mitochondrial DNA copy number (white blood cells) 1,338 females NA Illumina [7373492] (imputed) 1 mitochondrial DNA measurement http://www.ebi.ac.uk/efo/EFO_0006312 GCST007397 Genome-wide genotyping array 1338 2019-03-25 30704525 Guyatt AL 2019-01-31 Hum Genomics www.ncbi.nlm.nih.gov/pubmed/30704525 A genome-wide association study of mitochondrial DNA copy number in two population-based cohorts. Mitochondrial DNA copy number (white blood cells) 3,405 European ancestry females, 1,338 females NA Illumina [up to 7373492] (imputed) 1 mitochondrial DNA measurement http://www.ebi.ac.uk/efo/EFO_0006312 GCST007398 Genome-wide genotyping array 4743 2019-03-25 30704525 Guyatt AL 2019-01-31 Hum Genomics www.ncbi.nlm.nih.gov/pubmed/30704525 A genome-wide association study of mitochondrial DNA copy number in two population-based cohorts. Mitochondrial DNA copy number 5,461 European ancestry females, 1,338 females NA Illumina [up to 7373492] (imputed) 2 mitochondrial DNA measurement http://www.ebi.ac.uk/efo/EFO_0006312 GCST007399 Genome-wide genotyping array 6799 2019-11-04 31341412 Chen QY 2019-06-10 Int J Med Sci www.ncbi.nlm.nih.gov/pubmed/31341412 Locus 5p13.1 may be associated with the selection of cancer-related HBV core promoter mutations. Viral basal core promoter double mutation in hepatitis B virus surface antigen (HBsAg) seropositivity 218 Chinese ancestry asymptomatic cases, 191 Chinese ancestry asymptomatic controls 203 Chinese ancestry asymptomatic cases, 181 Chinese ancestry asymptomatic controls Illumina [25296] 0 viral subtype carrier status http://www.ebi.ac.uk/efo/EFO_0010234 GCST009000 Genome-wide genotyping array 409 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (Bifidobacterium) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 6 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90006987 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (Bacteroides) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 11 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90006988 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (Parabacteroides) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 6 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90006989 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (Prevotella) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 15 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90006990 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (Streptococcus) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 8 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90006991 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (unclassified genus belonging to family Clostridiaceae) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 7 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90006992 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (unclassified genus belonging to the order Clostridiales) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 13 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90006993 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 12 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90006994 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (unclassified genus belonging to family Lachnospiraceae) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 7 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90006995 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (Blautia) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 15 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90006996 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (Coprococcus) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 8 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90006997 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (Dorea) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 10 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90006998 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (unassigned genus belonging to family Lachnospiraceae) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 7 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90006999 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (unclassified genus belonging to family Ruminococcaceae) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 18 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90007000 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (Faecalibacterium) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 5 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90007001 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (Oscillospira) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 6 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90007002 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (Ruminococcus belonging to family Lachnospiraceae) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 14 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90007003 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (unassigned genus belonging to family Clostridiales) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 7 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90007004 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (Eubacterium belonging to family Erysipelotrichaceae) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 9 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90007005 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (unclassified genus belonging to family Erysipelotrichaceae) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 13 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90007006 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (Sutterella) 1,068 Japanese ancestry individuals NA Illumina [6380737] (imputed) 9 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90007007 Genome-wide genotyping array 1068 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (Prevotella) 527 Japanese ancestry men NA Illumina [544877] 2 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90007008 Genome-wide genotyping array 527 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (Faecalibacterium) 527 Japanese ancestry men NA Illumina [544877] 9 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90007009 Genome-wide genotyping array 527 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (Oscillospira) 541 Japanese ancestry women NA Illumina [545605] 7 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90007010 Genome-wide genotyping array 541 2020-12-04 33208821 Ishida S 2020-11-18 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33208821 Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Gut microbiota relative abundance (unclassified genus belonging to family Erysipelotrichaceae) 541 Japanese ancestry women NA Illumina [545605] 4 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90007011 Genome-wide genotyping array 541 2019-03-26 30642921 de Vries PS 2019-01-14 Blood www.ncbi.nlm.nih.gov/pubmed/30642921 A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology. Factor VII activity 20,014 European ancestry individuals, 3,420 African American individuals NA Affymetrix, Illumina [10044948] (imputed) 36 factor VII measurement http://www.ebi.ac.uk/efo/EFO_0004619 GCST007401 Genome-wide genotyping array 23434 2019-08-07 31066027 Nicoletti P 2019-05-07 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/31066027 Shared genetic risk factors across carbamazepine-induced hypersensitivity reactions. Carbamazepine-induced liver injury 12 European ancestry cases, 8,438 European ancestry controls NA Illumina [5271349] (imputed) 0 drug-induced liver injury, response to carbamazepine http://www.ebi.ac.uk/efo/EFO_0004228, http://www.ebi.ac.uk/efo/EFO_0008484 GCST008383 Genome-wide genotyping array 8450 2019-08-07 31066027 Nicoletti P 2019-05-07 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/31066027 Shared genetic risk factors across carbamazepine-induced hypersensitivity reactions. Carbamazepine-induced reaction with eosinophilia and systemic symptoms 25 European ancestry cases, 10,701 European ancestry controls NA Illumina [5271349] (imputed) 3 drug hypersensitivity syndrome, response to carbamazepine http://www.ebi.ac.uk/efo/EFO_1002004, http://www.ebi.ac.uk/efo/EFO_0008484 GCST008384 Genome-wide genotyping array 10726 2019-08-07 31066027 Nicoletti P 2019-05-07 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/31066027 Shared genetic risk factors across carbamazepine-induced hypersensitivity reactions. Carbamazepine-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN) 16 European ancestry cases, 8,438 European ancestry controls NA Illumina [5271349] (imputed) 0 Stevens-Johnson syndrome, toxic epidermal necrolysis, response to carbamazepine http://www.ebi.ac.uk/efo/EFO_0004276, http://www.ebi.ac.uk/efo/EFO_0004775, http://www.ebi.ac.uk/efo/EFO_0008484 GCST008385 Genome-wide genotyping array 8454 2019-08-07 31066027 Nicoletti P 2019-05-07 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/31066027 Shared genetic risk factors across carbamazepine-induced hypersensitivity reactions. Carbamazepine-induced serious cutaneous adverse reaction 43 European ancestry cases, 10,701 European ancestry controls NA Illumina [5271349] (imputed) 3 severe cutaneous adverse reaction, response to carbamazepine http://www.ebi.ac.uk/efo/EFO_0006346, http://www.ebi.ac.uk/efo/EFO_0008484 GCST008386 Genome-wide genotyping array 10744 2021-02-08 31366177 Prasad G 2019-07-30 Biomolecules www.ncbi.nlm.nih.gov/pubmed/31366177 Genome-Wide Association Study of Metabolic Syndrome Reveals Primary Genetic Variants at CETP Locus in Indians. Metabolic syndrome 1,596 Indo-European ancestry cases, 562 Indo-European ancestry controls 5,021 Indo-European ancestry cases, 2,914 Indo-European ancestry controls Illumina [519607] 0 metabolic syndrome http://www.ebi.ac.uk/efo/EFO_0000195 GCST011098 Genome-wide genotyping array 2158 2019-03-26 30642921 de Vries PS 2019-01-14 Blood www.ncbi.nlm.nih.gov/pubmed/30642921 A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology. Factor VII activity or levels 24,075 European ancestry individuals, 3,420 African American individuals NA Affymetrix, Illumina [10044948] (imputed) 6 factor VII measurement http://www.ebi.ac.uk/efo/EFO_0004619 GCST007402 Genome-wide genotyping array 27495 2018-12-03 28196072 Hagenaars SP 2017-02-14 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/28196072 Genetic prediction of male pattern baldness. Male-pattern baldness 52,874 British ancestry males NA NR [NR] (imputed) 335 Alopecia http://www.orpha.net/ORDO/Orphanet_79364 GCST006661 Genome-wide genotyping array 52874 2020-10-08 32769997 Zhou W 2020-08-07 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32769997 GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer. Thyroid stimulating hormone levels 119,715 European ancestry individuals NA Illumina [22400000] (imputed) 99 thyroid stimulating hormone measurement http://www.ebi.ac.uk/efo/EFO_0004748 GCST010653 Genome-wide genotyping array 119715 2019-07-26 30845926 van der Plaat DA 2019-03-07 BMC Pulm Med www.ncbi.nlm.nih.gov/pubmed/30845926 Limited overlap in significant hits between genome-wide association studies on two airflow obstruction definitions in the same population. Airway obstruction (FEV1/FVC<70%) in never smokers 77 European ancestry cases, 355 European ancestry controls NA Illumina [242926] 3 pulmonary function measurement http://www.ebi.ac.uk/efo/EFO_0003892 GCST008240 Genome-wide genotyping array 432 2019-07-26 30845926 van der Plaat DA 2019-03-07 BMC Pulm Med www.ncbi.nlm.nih.gov/pubmed/30845926 Limited overlap in significant hits between genome-wide association studies on two airflow obstruction definitions in the same population. Airway obstruction (FEV1/FVC 10000000] (imputed) 6 Hodgkins lymphoma http://www.ebi.ac.uk/efo/EFO_0000183 GCST007062 Genome-wide genotyping array 27750 2019-08-07 31009812 Hung RJ 2019-04-19 J Thorac Oncol www.ncbi.nlm.nih.gov/pubmed/31009812 Lung Cancer Risk in Never Smokers of European Descent is Associated with Genetic Variation in the 5P15.33 TERT-CLPTM1L Region. Adenocarcinoma in never smokers 1,837 European ancestry cases, 5,355 European ancestry controls 672 European ancestry cases, 940 European ancestry controls Illumina [at least 517482] (imputed) 1 lung adenocarcinoma http://www.ebi.ac.uk/efo/EFO_0000571 GCST008375 Genome-wide genotyping array 7192 2019-08-07 31009812 Hung RJ 2019-04-19 J Thorac Oncol www.ncbi.nlm.nih.gov/pubmed/31009812 Lung Cancer Risk in Never Smokers of European Descent is Associated with Genetic Variation in the 5P15.33 TERT-CLPTM1L Region. Lung cancer in never smokers 2,676 European ancestry cases, 5,355 European ancestry controls 960 European ancestry cases, 940 European ancestry controls Illumina [at least 517482] (imputed) 2 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST008376 Genome-wide genotyping array 8031 2020-02-17 31630189 Casanova F 2019-10-20 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31630189 A genome-wide association study implicates multiple mechanisms influencing raised urinary albumin-creatinine ratio. Urinary albumin-to-creatinine ratio 437,027 European ancestry individuals 60,130 individuals NR [12082474] (imputed) 59 urinary albumin to creatinine ratio http://www.ebi.ac.uk/efo/EFO_0007778 GCST009640 Genome-wide genotyping array 437027 2020-02-19 31856834 Chen Z 2019-12-19 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/31856834 Genome-wide association study in Chinese cohort identifies one novel hypospadias risk associated locus at 12q13.13. Hypospadias (moderate to severe) 197 Han Chinese ancestry cases, 933 Han Chinese ancestry controls 255 Han Chinese ancestry cases, 573 Han Chinese ancestry controls Illumina [3015028] (imputed) 1 hypospadias http://www.ebi.ac.uk/efo/EFO_0004209 GCST009672 Genome-wide genotyping array 1130 2020-10-27 32227112 Lee MA 2020-03-30 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/32227112 Common variation at 16p11.2 is associated with glycosuria in pregnancy: Findings from a genome-wide association study in European women. Glycosuria in pregnancy (maternal genotype effect) 1,249 European ancestry cases, 5,140 European ancestry controls NA Illumina [9323831] (imputed) 2 gestational blood glucose measurement, parental genotype effect measurement, Glycosuria http://www.ebi.ac.uk/efo/EFO_0009698, http://www.ebi.ac.uk/efo/EFO_0005939, http://purl.obolibrary.org/obo/HP_0003076 GCST010720 Genome-wide genotyping array 6389 2020-10-27 32227112 Lee MA 2020-03-30 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/32227112 Common variation at 16p11.2 is associated with glycosuria in pregnancy: Findings from a genome-wide association study in European women. Glycosuria in pregnancy (offspring genotype effect) 747 European ancestry cases, 2,991 European ancestry controls NA Illumina [9873828] (imputed) 5 gestational blood glucose measurement, fetal genotype effect measurement, Glycosuria http://www.ebi.ac.uk/efo/EFO_0009698, http://www.ebi.ac.uk/efo/EFO_0007959, http://purl.obolibrary.org/obo/HP_0003076 GCST010719 Genome-wide genotyping array 3738 2020-10-27 32227112 Lee MA 2020-03-30 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/32227112 Common variation at 16p11.2 is associated with glycosuria in pregnancy: Findings from a genome-wide association study in European women. Glycosuria in pregnancy (maternal and offspring genotype effect) 1,996 European ancestry cases, 8,131 European ancestry controls NA Illumina [up to 9873828] (imputed) 1 gestational blood glucose measurement, fetal genotype effect measurement, parental genotype effect measurement, Glycosuria http://www.ebi.ac.uk/efo/EFO_0009698, http://www.ebi.ac.uk/efo/EFO_0007959, http://www.ebi.ac.uk/efo/EFO_0005939, http://purl.obolibrary.org/obo/HP_0003076 GCST010718 Genome-wide genotyping array 10127 2020-03-09 31862735 Karsai G 2019-12-20 J Biol Chem www.ncbi.nlm.nih.gov/pubmed/31862735 FADS3 is a delta14Z sphingoid base desaturase that contributes to gender differences to the human plasma sphingolipidome. Sphingolipid d18:1/d18:2 ratio 658 European ancestry individuals NA NR [2557249] (imputed) 1 sphingolipid measurement http://www.ebi.ac.uk/efo/EFO_0004622 GCST009756 Genome-wide genotyping array 658 2019-02-07 30108283 Granot-Hershkovitz E 2018-08-14 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30108283 A study of Kibbutzim in Israel reveals risk factors for cardiometabolic traits and subtle population structure. Pulse rate 733 Ashkenazi Jewish ancestry individuals (founder/population isolate), 168 Sephardi Jewish, North African Jewish, Middle Eastern, Caucasian and Yemenite Jewish individuals 1,620 individuals Illumina [212505] (imputed) 0 heart rate http://www.ebi.ac.uk/efo/EFO_0004326 GCST007051 Genome-wide genotyping array 901 2019-02-07 30108283 Granot-Hershkovitz E 2018-08-14 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30108283 A study of Kibbutzim in Israel reveals risk factors for cardiometabolic traits and subtle population structure. Lipoprotein (a) levels 733 Ashkenazi Jewish ancestry individuals (founder/population isolate), 168 Sephardi Jewish, North African Jewish, Middle Eastern, Caucasian and Yemenite Jewish individuals NA Illumina [212505] (imputed) 10 lipoprotein A measurement http://www.ebi.ac.uk/efo/EFO_0006925 GCST007052 Genome-wide genotyping array 901 2019-02-07 30108283 Granot-Hershkovitz E 2018-08-14 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30108283 A study of Kibbutzim in Israel reveals risk factors for cardiometabolic traits and subtle population structure. Body mass index 733 Ashkenazi Jewish ancestry individuals (founder/population isolate), 168 Sephardi Jewish, North African Jewish, Middle Eastern, Caucasian and Yemenite Jewish individuals 1,620 individuals Illumina [212505] (imputed) 1 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST007053 Genome-wide genotyping array 901 2019-02-07 30108283 Granot-Hershkovitz E 2018-08-14 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30108283 A study of Kibbutzim in Israel reveals risk factors for cardiometabolic traits and subtle population structure. Weight 733 Ashkenazi Jewish ancestry individuals (founder/population isolate), 168 Sephardi Jewish, North African Jewish, Middle Eastern, Caucasian and Yemenite Jewish individuals 1,620 individuals Illumina [212505] (imputed) 2 body weight http://www.ebi.ac.uk/efo/EFO_0004338 GCST007054 Genome-wide genotyping array 901 2019-02-07 30108283 Granot-Hershkovitz E 2018-08-14 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30108283 A study of Kibbutzim in Israel reveals risk factors for cardiometabolic traits and subtle population structure. Waist circumference 733 Ashkenazi Jewish ancestry individuals (founder/population isolate), 168 Sephardi Jewish, North African Jewish, Middle Eastern, Caucasian and Yemenite Jewish individuals 1,620 individuals Illumina [212505] (imputed) 1 waist circumference http://www.ebi.ac.uk/efo/EFO_0004342 GCST007055 Genome-wide genotyping array 901 2019-02-07 30108283 Granot-Hershkovitz E 2018-08-14 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30108283 A study of Kibbutzim in Israel reveals risk factors for cardiometabolic traits and subtle population structure. Waist-hip ratio 733 Ashkenazi Jewish ancestry individuals (founder/population isolate), 168 Sephardi Jewish, North African Jewish, Middle Eastern, Caucasian and Yemenite Jewish individuals 1620 individuals Illumina [212505] (imputed) 1 waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0004343 GCST007056 Genome-wide genotyping array 901 2019-02-07 30108283 Granot-Hershkovitz E 2018-08-14 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30108283 A study of Kibbutzim in Israel reveals risk factors for cardiometabolic traits and subtle population structure. Height 733 Ashkenazi Jewish ancestry individuals (founder/population isolate), 168 Sephardi Jewish, North African Jewish, Middle Eastern, Caucasian and Yemenite Jewish individuals 1,620 individuals Illumina [212505] (imputed) 0 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST007057 Genome-wide genotyping array 901 2019-02-07 30108283 Granot-Hershkovitz E 2018-08-14 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30108283 A study of Kibbutzim in Israel reveals risk factors for cardiometabolic traits and subtle population structure. Hip circumference 733 Ashkenazi Jewish ancestry individuals (founder/population isolate), 168 Sephardi Jewish, North African Jewish, Middle Eastern, Caucasian and Yemenite Jewish individuals 1,620 individuals Illumina [212505] (imputed) 1 hip circumference http://www.ebi.ac.uk/efo/EFO_0005093 GCST007058 Genome-wide genotyping array 901 2020-10-30 31844061 Malaria Genomic Epidemiology Network 2019-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/31844061 Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania. Malaria 7,957 African ancestry cases, 7,746 African ancestry controls, 718 Asian ancestry cases, 546 Asian ancestry controls, 402 Oceanian cases, 374 Oceanian controls NR Illumina [1492601] (imputed) 100 malaria http://www.ebi.ac.uk/efo/EFO_0001068 GCST010725 Genome-wide genotyping array 17743 2020-02-26 31841133 Chen G 2019-12-16 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31841133 Refining genome-wide associated loci for serum uric acid in individuals with African ancestry. Serum uric acid levels 4,126 African ancestry individuals, 5,007 African American individuals NA Affymetrix, Illumina [up to 18219730] (imputed) 4 uric acid measurement http://www.ebi.ac.uk/efo/EFO_0004761 GCST009699 Genome-wide genotyping array 9133 2020-06-26 31837886 Kennedy OJ 2019-12-02 Am J Kidney Dis www.ncbi.nlm.nih.gov/pubmed/31837886 Coffee Consumption and Kidney Function: A Mendelian Randomization Study. Coffee consumption (cups per day) 227,666 British ancestry individuals NA NR [NR] 25 cups of coffee per day measurement http://www.ebi.ac.uk/efo/EFO_0006782 GCST010108 Genome-wide genotyping array 227666 2020-02-19 31852448 Chiang KM 2019-12-18 BMC Genet www.ncbi.nlm.nih.gov/pubmed/31852448 Genome-wide association study of morbid obesity in Han Chinese. Obesity (extreme) 575 Han Chinese ancestry cases, 1,707 Han Chinese ancestry controls 535 Han Chinese ancestry cases, 9,145 Han Chinese ancestry controls Affymetrix [562523] 2 obesity http://www.ebi.ac.uk/efo/EFO_0001073 GCST009673 Genome-wide genotyping array 2282 2019-09-30 30858448 Tekola-Ayele F 2019-03-11 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30858448 Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine. Birth weight or body mass index (pleiotropy) 153,781 European and unknown ancestry individuals with birth weight measurements, 339,224 European and unknown ancestry individuals with body mass index measurements NA NR [2590752] 0 body mass index, birth weight http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004344 GCST008773 Genome-wide genotyping array 493005 2019-09-30 30858448 Tekola-Ayele F 2019-03-11 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30858448 Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine. Birth weight or waist-hip ratio (pleiotropy) 153,781 European and unknown ancestry individuals with birth weight measurements, 224,459 European and unknown ancestry individuals with waist-hip ratio measurements NA NR [2566817] 0 waist-hip ratio, birth weight http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004344 GCST008774 Genome-wide genotyping array 378240 2019-09-30 30858448 Tekola-Ayele F 2019-03-11 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30858448 Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine. Birth weight or waist circumference (pleiotropy) 153,781 European and unknown ancestry individuals with birth weight measurements, 224,459 European and unknown ancestry individuals with waist circumference measurements NA NR [2569939] 0 waist circumference, birth weight http://www.ebi.ac.uk/efo/EFO_0004342, http://www.ebi.ac.uk/efo/EFO_0004344 GCST008775 Genome-wide genotyping array 378240 2019-09-30 30858448 Tekola-Ayele F 2019-03-11 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30858448 Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine. Birth weight or type 2 diabetes (pleiotropy) 153,781 European and unknown ancestry individuals with birth weight measurements, 110,452 European and unknown ancestry individuals with type 2 diabetes data NA NR [2893797] 0 type II diabetes mellitus, birth weight http://www.ebi.ac.uk/efo/EFO_0001360, http://www.ebi.ac.uk/efo/EFO_0004344 GCST008776 Genome-wide genotyping array 264235 2019-09-30 30858448 Tekola-Ayele F 2019-03-11 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30858448 Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine. Birth weight or fasting glucose levels (pleiotropy) 153,781 European and unknown ancestry individuals with birth weight measurements, 46,186 European and unknown ancestry individuals with fasting glucose measurements NA NR [2495051] 0 birth weight, fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004344, http://www.ebi.ac.uk/efo/EFO_0004465 GCST008777 Genome-wide genotyping array 199967 2019-09-30 30858448 Tekola-Ayele F 2019-03-11 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30858448 Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine. Birth weight or fasting insulin levels (pleiotropy) 153,781 European and unknown ancestry individuals with birth weight measurements, 46,186 European and unknown ancestry individuals with fasting insulin measurements NA NR [2495051] 0 birth weight, fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004344, http://www.ebi.ac.uk/efo/EFO_0004466 GCST008778 Genome-wide genotyping array 199967 2019-09-30 30858448 Tekola-Ayele F 2019-03-11 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30858448 Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine. Birth weight or hemoglobin A1C levels (pleiotropy) 153,781 European and unknown ancestry individuals with birth weight measurements, 46,368 European and unknown ancestry individuals with hemoglobin A1C measurements NA NR [2566561] 0 HbA1c measurement, birth weight http://www.ebi.ac.uk/efo/EFO_0004541, http://www.ebi.ac.uk/efo/EFO_0004344 GCST008779 Genome-wide genotyping array 200150 2019-09-30 30858448 Tekola-Ayele F 2019-03-11 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30858448 Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine. Birth weight or insulin secretion (pleiotropy) 153,781 European and unknown ancestry individuals with birth weight measurements, 5,318 European and unknown ancestry individuals with insulin secretion measurements NA NR [2460930] 0 insulin secretion measurement, birth weight http://www.ebi.ac.uk/efo/EFO_0008001, http://www.ebi.ac.uk/efo/EFO_0004344 GCST008780 Genome-wide genotyping array 159099 2019-09-30 30858448 Tekola-Ayele F 2019-03-11 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30858448 Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine. Birth weight or insulin sensitivity index (pleiotropy) 153,781 European and unknown ancestry individuals with birth weight measurements, 16,753 European and unknown ancestry individuals with insulin sensitivity measurements NA NR [2459303] 0 insulin sensitivity measurement, birth weight http://www.ebi.ac.uk/efo/EFO_0004471, http://www.ebi.ac.uk/efo/EFO_0004344 GCST008781 Genome-wide genotyping array 170534 2019-09-30 30858448 Tekola-Ayele F 2019-03-11 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30858448 Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine. Birth weight or coronary artery disease (pleiotropy) 153,781 European and unknown ancestry individuals with birth weight measurements, 184,305 European and unknown ancestry individuals with coronary artery disease data NA NR [8544005] 0 birth weight, coronary artery disease http://www.ebi.ac.uk/efo/EFO_0004344, http://www.ebi.ac.uk/efo/EFO_0001645 GCST008782 Genome-wide genotyping array 338086 2019-09-30 30858448 Tekola-Ayele F 2019-03-11 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30858448 Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine. Birth weight or myocardial infarction (pleiotropy) 153,781 European and unknown ancestry individuals with birth weight measurements, 129,000 European and unknown ancestry individuals with myocardial infarction data NA NR [8541959] 0 birth weight, myocardial infarction http://www.ebi.ac.uk/efo/EFO_0004344, http://www.ebi.ac.uk/efo/EFO_0000612 GCST008783 Genome-wide genotyping array 282781 2019-09-30 30858448 Tekola-Ayele F 2019-03-11 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30858448 Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine. Birth weight or LDL cholesterol levels (pleiotropy) 153,781 European and unknown ancestry individuals with birth weight measurements, 188,577 European and unknown ancestry individuals with LDL cholesterol measurements NA NR [2471777] 0 low density lipoprotein cholesterol measurement, birth weight http://www.ebi.ac.uk/efo/EFO_0004611, http://www.ebi.ac.uk/efo/EFO_0004344 GCST008784 Genome-wide genotyping array 342358 2019-09-30 30858448 Tekola-Ayele F 2019-03-11 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30858448 Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine. Birth weight or HDL cholesterol levels (pleiotropy) 153,781 European and unknown ancestry individuals with birth weight measurements, 188,577 European and unknown ancestry individuals with HDL cholesterol measurements NA NR [2481375] 0 birth weight, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004344, http://www.ebi.ac.uk/efo/EFO_0004612 GCST008785 Genome-wide genotyping array 342358 2019-09-30 30858448 Tekola-Ayele F 2019-03-11 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30858448 Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine. Birth weight or total cholesterol levels (pleiotropy) 153,781 European and unknown ancestry individuals with birth weight measurements, 188,577 European and unknown ancestry individuals with total cholesterol measurements NA NR [2480907] 0 total cholesterol measurement, birth weight http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0004344 GCST008786 Genome-wide genotyping array 342358 2019-09-30 30858448 Tekola-Ayele F 2019-03-11 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30858448 Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine. Birth weight or triglycerides levels (pleiotropy) 153,781 European and unknown ancestry individuals with birth weight measurements, 188,577 European and unknown ancestry individuals with triglycerides measurements NA NR [2473236] 0 triglyceride measurement, birth weight http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0004344 GCST008787 Genome-wide genotyping array 342358 2019-05-15 30868120 Berghuis B 2019-01-17 Epilepsia Open www.ncbi.nlm.nih.gov/pubmed/30868120 A genome-wide association study of sodium levels and drug metabolism in an epilepsy cohort treated with carbamazepine and oxcarbazepine. Sodium levels in epilepsy 1,252 European ancestry cases NA Illumina [NR] 1 sodium measurement http://www.ebi.ac.uk/efo/EFO_0009282 GCST007814 Genome-wide genotyping array 1252 2019-05-15 30868120 Berghuis B 2019-01-17 Epilepsia Open www.ncbi.nlm.nih.gov/pubmed/30868120 A genome-wide association study of sodium levels and drug metabolism in an epilepsy cohort treated with carbamazepine and oxcarbazepine. Carbamazepine- or oxcarbazepine-induced hyponatremia in epilepsy 448 European ancestry cases, 804 European ancestry controls NA Illumina [NR] 3 carbamazepine-induced hyponatremia, response to oxcarbazepine, oxcarbazepine-induced hyponatremia, response to carbamazepine http://www.ebi.ac.uk/efo/EFO_0009894, http://www.ebi.ac.uk/efo/EFO_0009893, http://www.ebi.ac.uk/efo/EFO_0009895, http://www.ebi.ac.uk/efo/EFO_0008484 GCST007809 Genome-wide genotyping array 1252 2019-05-15 30868120 Berghuis B 2019-01-17 Epilepsia Open www.ncbi.nlm.nih.gov/pubmed/30868120 A genome-wide association study of sodium levels and drug metabolism in an epilepsy cohort treated with carbamazepine and oxcarbazepine. Severe carbamazepine- or oxcarbazepine-induced hyponatremia in epilepsy 61 European ancestry cases, at least 804 European ancestry controls NA Illumina [NR] 3 carbamazepine-induced hyponatremia, response to oxcarbazepine, oxcarbazepine-induced hyponatremia, response to carbamazepine http://www.ebi.ac.uk/efo/EFO_0009894, http://www.ebi.ac.uk/efo/EFO_0009893, http://www.ebi.ac.uk/efo/EFO_0009895, http://www.ebi.ac.uk/efo/EFO_0008484 GCST007810 Genome-wide genotyping array 865 2019-05-15 30868120 Berghuis B 2019-01-17 Epilepsia Open www.ncbi.nlm.nih.gov/pubmed/30868120 A genome-wide association study of sodium levels and drug metabolism in an epilepsy cohort treated with carbamazepine and oxcarbazepine. Carbamazepine-induced hyponatremia in epilepsy 331 European ancestry cases, 700 European ancestry controls NA Illumina [NR] 7 carbamazepine-induced hyponatremia, response to carbamazepine http://www.ebi.ac.uk/efo/EFO_0009894, http://www.ebi.ac.uk/efo/EFO_0008484 GCST007811 Genome-wide genotyping array 1031 2019-05-15 30868120 Berghuis B 2019-01-17 Epilepsia Open www.ncbi.nlm.nih.gov/pubmed/30868120 A genome-wide association study of sodium levels and drug metabolism in an epilepsy cohort treated with carbamazepine and oxcarbazepine. Oxcarbazepine-induced hyponatremia in epilepsy 170 European ancestry cases, 127 European ancestry controls NA Illumina [NR] 1 response to oxcarbazepine, oxcarbazepine-induced hyponatremia http://www.ebi.ac.uk/efo/EFO_0009893, http://www.ebi.ac.uk/efo/EFO_0009895 GCST007812 Genome-wide genotyping array 297 2019-05-15 30868120 Berghuis B 2019-01-17 Epilepsia Open www.ncbi.nlm.nih.gov/pubmed/30868120 A genome-wide association study of sodium levels and drug metabolism in an epilepsy cohort treated with carbamazepine and oxcarbazepine. Carbamazepine metabolism (carbamazepine-10,11-diol to carbamazepine ratio) in epilepsy 468 European ancestry cases NA Illumina [NR] 3 carbamazepine metabolite measurement http://www.ebi.ac.uk/efo/EFO_0009891 GCST007813 Genome-wide genotyping array 468 2019-05-08 30854688 Wang C 2019-03-10 Hepatology www.ncbi.nlm.nih.gov/pubmed/30854688 Genome Wide Association Studies of Specific Antinuclear Autoantibody Sub-phenotypes in Primary Biliary Cholangitis. Anti-sp100 seropositivity in primary biliary cholangitis 211 Han Chinese ancestry cases, 711 Han Chinese ancestry controls 234 Han Chinese ancestry cases, 1,018 Han Chinese ancestry controls Illumina [794531] 2 antinuclear antibody measurement http://www.ebi.ac.uk/efo/EFO_0005949 GCST007737 Genome-wide genotyping array 922 2019-05-08 30854688 Wang C 2019-03-10 Hepatology www.ncbi.nlm.nih.gov/pubmed/30854688 Genome Wide Association Studies of Specific Antinuclear Autoantibody Sub-phenotypes in Primary Biliary Cholangitis. Anti-gp210 seropositivity in primary biliary cholangitis 350 Han Chinese ancestry cases, 562 Han Chinese ancestry controls 444 Han Chinese ancestry cases, 808 Han Chinese ancestry controls Illumina [794694] 0 antinuclear antibody measurement http://www.ebi.ac.uk/efo/EFO_0005949 GCST007736 Genome-wide genotyping array 912 2019-06-18 30866520 Er LK 2019-03-07 Int J Mol Sci www.ncbi.nlm.nih.gov/pubmed/30866520 Circulating Chemerin Levels, but not the RARRES2 Polymorphisms, Predict the Long-Term Outcome of Angiographically Confirmed Coronary Artery Disease. Chemerin levels 2,197 Taiwanese individuals NA Affymetrix [614820] 1 chemerin measurement http://www.ebi.ac.uk/efo/EFO_0004573 GCST007900 Genome-wide genotyping array 2197 2019-05-01 30852652 Schlicht K 2019-03-09 Hum Genet www.ncbi.nlm.nih.gov/pubmed/30852652 The metabolic network coherence of human transcriptomes is associated with genetic variation at the cadherin 18 locus. Metabolic coherence (transcriptomic) 369 European ancestry individuals 3,783 European ancestry individuals Illumina [1067702] 1 metabolic network measurement, transcriptome measurement http://www.ebi.ac.uk/efo/EFO_0009864, http://www.ebi.ac.uk/efo/EFO_0009865 GCST007690 Genome-wide genotyping array 369 2021-07-27 33479212 Yao X 2021-01-21 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/33479212 Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders. Attention deficit hyperactivity disorder (MTAG) at least 19,099 European ancestry cases, at least 34,194 European ancestry controls 2,726 European ancestry cases, 16,299 European ancestry controls NR [NR] 9 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST012093 Genome-wide genotyping array 53293 2021-07-27 33479212 Yao X 2021-01-21 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/33479212 Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders. Autism spectrum disorder (MTAG) at least 18,381 European ancestry cases, at least 27,969 European ancestry controls NA NR [NR] 9 autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0003756 GCST012092 Genome-wide genotyping array 46350 2021-07-27 33479212 Yao X 2021-01-21 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/33479212 Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders. Bipolar disorder (MTAG) at least 20,352 European ancestry cases, at least 31,358 European ancestry controls NA NR [NR] 54 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST012091 Genome-wide genotyping array 51710 2021-07-27 33479212 Yao X 2021-01-21 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/33479212 Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders. Major depressive disorder (MTAG) at least 170,756 European ancestry cases, at least 329,443 European ancestry controls NA NR [NR] 74 major depressive disorder http://purl.obolibrary.org/obo/MONDO_0002009 GCST012090 Genome-wide genotyping array 500199 2021-07-27 33479212 Yao X 2021-01-21 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/33479212 Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders. Schizophrenia (MTAG) at least 33,640 European ancestry cases, at least 43,456 European ancestry controls NA NR [NR] 90 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST012089 Genome-wide genotyping array 77096 2021-07-27 33479212 Yao X 2021-01-21 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/33479212 Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders. Neuropsychiatric disorders 19,099 European ancestry attention deficit hyperactivity disorder cases, 18,381 European ancestry autism spectrum disorder cases, 20,352 European ancestry bipolar disorder cases, 170,756 European ancestry major depressive disorder cases, 33,640 European ancestry schizophrenia cases, 466,420 European ancestry controls NA NR [NR] 43 attention deficit hyperactivity disorder, schizophrenia, autism spectrum disorder, bipolar disorder, major depressive disorder http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0003756, http://www.ebi.ac.uk/efo/EFO_0000289, http://purl.obolibrary.org/obo/MONDO_0002009 GCST012088 Genome-wide genotyping array 728648 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Hyperglycemia 11,794 European ancestry women NA NR [18717781] (imputed) 1 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST007744 Genome-wide genotyping array 11794 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Hyperglycemia in obesity 3,431 European ancestry women NA NR [18717781] (imputed) 0 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST007745 Genome-wide genotyping array 3431 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Hyperglycemia in non-obese individuals 8,363 European ancestry women NA NR [18717781] (imputed) 0 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST007746 Genome-wide genotyping array 8363 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Hyperglycemia in lower physical activity 6,818 European ancestry women NA NR [18717781] (imputed) 0 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST007747 Genome-wide genotyping array 6818 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Hyperglycemia in higher physical activity 4,976 European ancestry women NA NR [18717781] (imputed) 2 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST007748 Genome-wide genotyping array 4976 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Hyperglycemia in more-fat diet 10,707 European ancestry women NA NR [18717781] (imputed) 1 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST007749 Genome-wide genotyping array 10707 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Hyperglycemia in less-fat diet 1,087 European ancestry women NA NR [18717781] (imputed) 0 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST007750 Genome-wide genotyping array 1087 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Homeostasis model assessment of insulin resistance in obesity 3,431 European ancestry women NA NR [18717781] (imputed) 0 insulin resistance http://www.ebi.ac.uk/efo/EFO_0002614 GCST007751 Genome-wide genotyping array 3431 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Homeostasis model assessment of insulin resistance in non-obese individuals 8,363 European ancestry women NA NR [18717781] (imputed) 0 insulin resistance http://www.ebi.ac.uk/efo/EFO_0002614 GCST007752 Genome-wide genotyping array 8363 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Homeostasis model assessment of insulin resistance in higher physical activity 4,976 European ancestry women NA NR [18717781] (imputed) 0 insulin resistance http://www.ebi.ac.uk/efo/EFO_0002614 GCST007753 Genome-wide genotyping array 4976 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Homeostasis model assessment of insulin resistance in lower physical activity 6,818 European ancestry women NA NR [18717781] (imputed) 0 insulin resistance http://www.ebi.ac.uk/efo/EFO_0002614 GCST007754 Genome-wide genotyping array 6818 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Homeostasis model assessment of insulin resistance in more-fat diet 10,707 European ancestry women NA NR [18717781] (imputed) 2 insulin resistance http://www.ebi.ac.uk/efo/EFO_0002614 GCST007755 Genome-wide genotyping array 10707 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Homeostasis model assessment of insulin resistance in less-fat diet 1,087 European ancestry women NA NR [18717781] (imputed) 2 insulin resistance http://www.ebi.ac.uk/efo/EFO_0002614 GCST007756 Genome-wide genotyping array 1087 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Hyperglycemia x BMI interaction 8,363 European ancestry non-obese women, 3,431 European ancestry obese women NA NR [18717781] (imputed) 0 body mass index, fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004465 GCST007757 Genome-wide genotyping array 11794 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Hyperglycemia x physical activity interaction 4,976 European ancestry active women, 6,818 European ancestry inactive women NA NR [18717781] (imputed) 0 physical activity measurement, fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004465 GCST007758 Genome-wide genotyping array 11794 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Hyperglycemia x saturated fatty acids interaction 1,087 European ancestry less-fat diet women, 10,707 European ancestry more-fat diet women NA NR [18717781] (imputed) 0 fatty acid measurement, fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0005110, http://www.ebi.ac.uk/efo/EFO_0004465 GCST007759 Genome-wide genotyping array 11794 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Hyperinsulinemia 11,794 European ancestry women NA NR [18717781] (imputed) 0 fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004466 GCST007760 Genome-wide genotyping array 11794 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Homeostasis model assessment of insulin resistance 11,794 European ancestry women NA NR [18717781] (imputed) 2 insulin resistance http://www.ebi.ac.uk/efo/EFO_0002614 GCST007761 Genome-wide genotyping array 11794 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Hyperinsulinemia x BMI interaction 8,363 European ancestry non-obese women, 3,431 European ancestry obese women NA NR [18717781] (imputed) 1 body mass index, fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004466 GCST007762 Genome-wide genotyping array 11794 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Homeostasis model assessment of insulin resistance x BMI interaction 8,363 European ancestry non-obese women, 3,431 European ancestry obese women NA NR [18717781] (imputed) 0 insulin resistance, body mass index http://www.ebi.ac.uk/efo/EFO_0002614, http://www.ebi.ac.uk/efo/EFO_0004340 GCST007763 Genome-wide genotyping array 11794 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Hyperinsulinemia x physical activity interaction 4,976 European ancestry active women, 6,818 European ancestry inactive women NA NR [18717781] (imputed) 1 physical activity measurement, fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0008002, http://www.ebi.ac.uk/efo/EFO_0004466 GCST007764 Genome-wide genotyping array 11794 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Homeostasis model assessment of insulin resistance x physical activity interaction 4,976 European ancestry active women, 6,818 European ancestry inactive women NA NR [18717781] (imputed) 0 insulin resistance, physical activity measurement http://www.ebi.ac.uk/efo/EFO_0002614, http://www.ebi.ac.uk/efo/EFO_0008002 GCST007765 Genome-wide genotyping array 11794 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Hyperinsulinemia x saturated fatty acids interaction 1,087 European ancestry less-fat diet women, 10,707 European ancestry more-fat diet women NA NR [18717781] (imputed) 1 fatty acid measurement, fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0005110, http://www.ebi.ac.uk/efo/EFO_0004466 GCST007766 Genome-wide genotyping array 11794 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Homeostasis model assessment of insulin resistance x saturated fatty acids interaction 1,087 European ancestry less-fat diet women, 10,707 European ancestry more-fat diet women NA NR [18717781] (imputed) 1 fatty acid measurement, insulin resistance http://www.ebi.ac.uk/efo/EFO_0005110, http://www.ebi.ac.uk/efo/EFO_0002614 GCST007767 Genome-wide genotyping array 11794 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Hyperinsulinemia in obesity 3,431 European ancestry women NA NR [18717781] (imputed) 1 fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004466 GCST007768 Genome-wide genotyping array 3431 2019-04-15 30339177 Shane B 2018-10-19 Am J Clin Nutr www.ncbi.nlm.nih.gov/pubmed/30339177 The 677C→T variant of MTHFR is the major genetic modifier of biomarkers of folate status in a young, healthy Irish population. Red blood cell folate levels 2,232 Irish ancestry individuals NA Illumina [758443] 2 red blood cell folate measurement http://www.ebi.ac.uk/efo/EFO_0009703 GCST007580 Genome-wide genotyping array 2232 2019-04-15 30339177 Shane B 2018-10-19 Am J Clin Nutr www.ncbi.nlm.nih.gov/pubmed/30339177 The 677C→T variant of MTHFR is the major genetic modifier of biomarkers of folate status in a young, healthy Irish population. Serum folate levels 2,232 Irish ancestry individuals NA Illumina [758443] 2 folic acid measurement http://www.ebi.ac.uk/efo/EFO_0005111 GCST007579 Genome-wide genotyping array 2232 2019-04-15 30339177 Shane B 2018-10-19 Am J Clin Nutr www.ncbi.nlm.nih.gov/pubmed/30339177 The 677C→T variant of MTHFR is the major genetic modifier of biomarkers of folate status in a young, healthy Irish population. Plasma homocysteine levels 2,232 Irish ancestry individuals NA Illumina [758443] 5 homocysteine measurement http://www.ebi.ac.uk/efo/EFO_0004578 GCST007578 Genome-wide genotyping array 2232 2019-02-28 30287865 Pinar A 2018-10-04 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/30287865 Genome-wide association study reveals novel genetic locus associated with intra-individual variability in response time. Intra-individual response time variability (response selection) 857 European ancestry individuals NA Illumina [5408162] (imputed) 0 intra-individual reaction time variability measurement http://www.ebi.ac.uk/efo/EFO_0009702 GCST007244 Genome-wide genotyping array 857 2019-02-28 30287865 Pinar A 2018-10-04 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/30287865 Genome-wide association study reveals novel genetic locus associated with intra-individual variability in response time. Intra-individual response time variability (selective attention) 857 European ancestry individuals NA Illumina [5408162] (imputed) 2 intra-individual reaction time variability measurement http://www.ebi.ac.uk/efo/EFO_0009702 GCST007243 Genome-wide genotyping array 857 2019-10-31 29593015 Montasser ME 2018-09-01 Circulation www.ncbi.nlm.nih.gov/pubmed/29593015 An APOO Pseudogene on Chromosome 5q Is Associated With Low-Density Lipoprotein Cholesterol Levels. Low density lipoprotein cholesterol levels 1,102 Old Order Amish (founder/genetic isolate) individuals 798 Old Order Amish (founder/genetic isolate) individuals Illumina [124907] 1 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST008990 Targeted genotyping array [Cardio-Metabochip] 1102 2020-02-19 31841498 Kampe A 2019-12-16 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/31841498 Genetic variation in GC and CYP2R1 affects 25-hydroxyvitamin D concentration and skeletal parameters: A genome-wide association study in 24-month-old Finnish children. Serum 25-Hydroxyvitamin D levels 761 Finnish ancestry infants NA Illumina [5072729] (imputed) 2 vitamin D measurement http://www.ebi.ac.uk/efo/EFO_0004631 GCST009671 Genome-wide genotyping array 761 2019-09-02 28628107 Jonsson S 2017-06-19 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28628107 Identification of sequence variants influencing immunoglobulin levels. IgA levels 16,883 Icelandic ancestry individuals 2,151 Swedish ancestry individuals Illumina [21568490] (imputed) 15 serum IgA measurement http://www.ebi.ac.uk/efo/EFO_0004912 GCST008568 Genome-wide genotyping array, Genome-wide sequencing 16883 2019-09-02 28628107 Jonsson S 2017-06-19 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28628107 Identification of sequence variants influencing immunoglobulin levels. Composite immunoglobulin trait (IgA x IgG x IgM) 14,183 Icelandic ancestry individuals 2,146 Swedish ancestry individuals Illumina [21568490] (imputed) 2 serum immunoglobulin measurement http://www.ebi.ac.uk/efo/EFO_0010127 GCST008569 Genome-wide genotyping array, Genome-wide sequencing 14183 2019-09-02 28628107 Jonsson S 2017-06-19 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28628107 Identification of sequence variants influencing immunoglobulin levels. Composite immunoglobulin trait (IgA x IgG/IgM) 14,183 Icelandic ancestry individuals 2,146 Swedish ancestry individuals Illumina [21568490] (imputed) 8 immunoglobulin isotype switching measurement http://www.ebi.ac.uk/efo/EFO_0010128 GCST008570 Genome-wide genotyping array, Genome-wide sequencing 14183 2019-09-02 28628107 Jonsson S 2017-06-19 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28628107 Identification of sequence variants influencing immunoglobulin levels. Composite immunoglobulin trait (IgA x IgG) 14,183 Icelandic ancestry individuals 2,146 Swedish ancestry individuals Illumina [21568490] (imputed) 1 immunoglobulin isotype switching measurement http://www.ebi.ac.uk/efo/EFO_0010128 GCST008571 Genome-wide genotyping array, Genome-wide sequencing 14183 2019-09-02 28628107 Jonsson S 2017-06-19 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28628107 Identification of sequence variants influencing immunoglobulin levels. Composite immunoglobulin trait (IgA/IgG) 14,183 Icelandic ancestry individuals 2,146 Swedish ancestry individuals Illumina [21568490] (imputed) 12 immunoglobulin isotype switching measurement http://www.ebi.ac.uk/efo/EFO_0010128 GCST008572 Genome-wide genotyping array, Genome-wide sequencing 14183 2019-09-02 28628107 Jonsson S 2017-06-19 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28628107 Identification of sequence variants influencing immunoglobulin levels. Composite immunoglobulin trait (IgA/IgM) 14,183 Icelandic ancestry individuals 2,146 Swedish ancestry individuals Illumina [21568490] (imputed) 9 immunoglobulin isotype switching measurement http://www.ebi.ac.uk/efo/EFO_0010128 GCST008573 Genome-wide genotyping array, Genome-wide sequencing 14183 2019-09-02 28628107 Jonsson S 2017-06-19 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28628107 Identification of sequence variants influencing immunoglobulin levels. Composite immunoglobulin trait (IgG/IgM) 14,183 Icelandic ancestry individuals 2,146 Swedish ancestry individuals Illumina [21568490] (imputed) 4 immunoglobulin isotype switching measurement http://www.ebi.ac.uk/efo/EFO_0010128 GCST008574 Genome-wide genotyping array, Genome-wide sequencing 14183 2019-09-02 28628107 Jonsson S 2017-06-19 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28628107 Identification of sequence variants influencing immunoglobulin levels. IgM levels 14,442 Icelandic ancestry individuals 2,157 Swedish ancestry individuals Illumina [21568490] (imputed) 13 serum IgM measurement http://www.ebi.ac.uk/efo/EFO_0004993 GCST008575 Genome-wide genotyping array, Genome-wide sequencing 14442 2019-09-02 28628107 Jonsson S 2017-06-19 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28628107 Identification of sequence variants influencing immunoglobulin levels. IgG levels 15,536 Icelandic ancestry individuals 2,158 Swedish ancestry individuals Illumina [21568490] (imputed) 8 serum IgG measurement http://www.ebi.ac.uk/efo/EFO_0004565 GCST008576 Genome-wide genotyping array, Genome-wide sequencing 15536 2018-10-19 30172743 Liang X 2018-08-30 Bone www.ncbi.nlm.nih.gov/pubmed/30172743 Assessing the genetic correlations between early growth parameters and bone mineral density: A polygenic risk score analysis. Total body bone mineral density 2,286 European ancestry individuals NA Affymetrix [753382] 6 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST006443 Genome-wide genotyping array 2286 2018-10-19 30172743 Liang X 2018-08-30 Bone www.ncbi.nlm.nih.gov/pubmed/30172743 Assessing the genetic correlations between early growth parameters and bone mineral density: A polygenic risk score analysis. Bone mineral density (hip) 2,286 European ancestry individuals NA Affymetrix [753382] 24 hip bone mineral density http://www.ebi.ac.uk/efo/EFO_0007702 GCST006444 Genome-wide genotyping array 2286 2018-10-19 30172743 Liang X 2018-08-30 Bone www.ncbi.nlm.nih.gov/pubmed/30172743 Assessing the genetic correlations between early growth parameters and bone mineral density: A polygenic risk score analysis. Femoral neck bone mineral density 2,286 European ancestry individuals NA Affymetrix [753382] 8 femoral neck bone mineral density http://www.ebi.ac.uk/efo/EFO_0007785 GCST006445 Genome-wide genotyping array 2286 2018-10-19 30172743 Liang X 2018-08-30 Bone www.ncbi.nlm.nih.gov/pubmed/30172743 Assessing the genetic correlations between early growth parameters and bone mineral density: A polygenic risk score analysis. Ulna and radius bone mineral density 2,286 European ancestry individuals NA Affymetrix [753382] 7 radius bone mineral density http://www.ebi.ac.uk/efo/EFO_0007933 GCST006446 Genome-wide genotyping array 2286 2018-10-19 30172743 Liang X 2018-08-30 Bone www.ncbi.nlm.nih.gov/pubmed/30172743 Assessing the genetic correlations between early growth parameters and bone mineral density: A polygenic risk score analysis. Bone mineral density (spine) 2,286 European ancestry individuals NA Affymetrix [753382] 3 spine bone mineral density http://www.ebi.ac.uk/efo/EFO_0007701 GCST006447 Genome-wide genotyping array 2286 2019-07-31 31028280 Ierodiakonou D 2019-04-26 J Expo Sci Environ Epidemiol www.ncbi.nlm.nih.gov/pubmed/31028280 Pathway analysis of a genome-wide gene by air pollution interaction study in asthmatic children. Post-bronchodilator FEV1 x air pollution (CO) interaction in childhood asthma 522 European ancestry children NA Illumina [474792] 6 forced expiratory volume, traffic air pollution measurement http://www.ebi.ac.uk/efo/EFO_0004314, http://www.ebi.ac.uk/efo/EFO_0007908 GCST008272 Genome-wide genotyping array 522 2019-07-31 31028280 Ierodiakonou D 2019-04-26 J Expo Sci Environ Epidemiol www.ncbi.nlm.nih.gov/pubmed/31028280 Pathway analysis of a genome-wide gene by air pollution interaction study in asthmatic children. Post-bronchodilator FEV1 x air pollution (NO2) interaction in childhood asthma 522 European ancestry children 88 African-American children Illumina [474792] 6 forced expiratory volume, traffic air pollution measurement http://www.ebi.ac.uk/efo/EFO_0004314, http://www.ebi.ac.uk/efo/EFO_0007908 GCST008273 Genome-wide genotyping array 522 2021-03-18 31846791 Kim HJ 2019-12-09 Chemosphere www.ncbi.nlm.nih.gov/pubmed/31846791 A genome-wide by PM10 interaction study identifies novel loci for lung function near BICD1 and IL1RN-IL1F10 genes in Korean adults. Lung function x fine particulate matter exposure levels interaction 1,826 Korean ancestry individuals 892 Korean ancestry individuals Illumina [197275] 0 pulmonary function measurement, particulate matter air pollution measurement http://www.ebi.ac.uk/efo/EFO_0003892, http://www.ebi.ac.uk/efo/EFO_0008255 GCST011299 Genome-wide genotyping array 1826 2020-01-22 31641590 Stevelink R 2019-10-11 Mol Genet Metab Rep www.ncbi.nlm.nih.gov/pubmed/31641590 Assessing the genetic association between vitamin B6 metabolism and genetic generalized epilepsy. Pyridoxal 5'-phosphate levels 2,232 Irish ancestry individuals NA NR [~ 6000000] (imputed) 2 vitamin B6 measurement http://www.ebi.ac.uk/efo/EFO_0004621 GCST009471 Genome-wide genotyping array 2232 2020-01-22 31641590 Stevelink R 2019-10-11 Mol Genet Metab Rep www.ncbi.nlm.nih.gov/pubmed/31641590 Assessing the genetic association between vitamin B6 metabolism and genetic generalized epilepsy. Plasma pyridoxal phosphate to pyridoxal ratio 2,232 Irish ancestry individuals NA NR [~ 6000000] (imputed) 2 vitamin B6 measurement http://www.ebi.ac.uk/efo/EFO_0004621 GCST009470 Genome-wide genotyping array 2232 2020-01-22 31641590 Stevelink R 2019-10-11 Mol Genet Metab Rep www.ncbi.nlm.nih.gov/pubmed/31641590 Assessing the genetic association between vitamin B6 metabolism and genetic generalized epilepsy. Pyridoxal levels 2,232 Irish ancestry individuals NA NR [~ 6000000] (imputed) 1 vitamin B6 measurement http://www.ebi.ac.uk/efo/EFO_0004621 GCST009469 Genome-wide genotyping array 2232 2020-01-22 31641590 Stevelink R 2019-10-11 Mol Genet Metab Rep www.ncbi.nlm.nih.gov/pubmed/31641590 Assessing the genetic association between vitamin B6 metabolism and genetic generalized epilepsy. 4-pyridoxic acid levels 2,232 Irish ancestry individuals NA NR [~ 6000000] (imputed) 0 vitamin B6 measurement http://www.ebi.ac.uk/efo/EFO_0004621 GCST009472 Genome-wide genotyping array 2232 2020-01-22 31641590 Stevelink R 2019-10-11 Mol Genet Metab Rep www.ncbi.nlm.nih.gov/pubmed/31641590 Assessing the genetic association between vitamin B6 metabolism and genetic generalized epilepsy. PAr index (pyridoxic acid/(pyridoxal 5′-phosphate + pyridoxal)) 2,232 Irish ancestry individuals NA NR [~ 6000000] (imputed) 0 vitamin B6 measurement http://www.ebi.ac.uk/efo/EFO_0004621 GCST009473 Genome-wide genotyping array 2232 2019-11-11 27453504 Rhee EP 2016-07-25 Nat Commun www.ncbi.nlm.nih.gov/pubmed/27453504 An exome array study of the plasma metabolome. Blood metabolite levels 2,076 European ancestry individuals 1,528 European ancestry individuals Illumina [81021] 1 blood metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005664 GCST009018 Exome genotyping array [Exome array] 2076 2019-07-02 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Height 17,286 African American individuals, 22,192 Hispanic/Latino individuals, 4,680 Asian ancestry individuals, 3,939 Native Hawaiian ancestry individuals, 647 Native American ancestry individuals, 1,052 individuals NA Illumina [34656550] (imputed) 214 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST008053 Genome-wide genotyping array 49796 2019-07-01 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Height 303,288 European ancestry individuals NA Illumina [~ 2500000] (imputed) 0 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST008040 Genome-wide genotyping array 303288 2019-07-01 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Height 253,288 European ancestry individuals, 17,286 African American individuals, 22,192 Hispanic/Latino individuals, 4,680 Asian ancestry individuals, 3,939 Native Hawaiian ancestry individuals, 647 Native American ancestry individuals, 1,052 individuals NA Illumina [~ 2500000] (imputed) 0 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST008041 Genome-wide genotyping array 303084 2019-07-02 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. QRS duration 3,274 African American individuals, 13,420 Hispanic/Latino individuals, 126 Asian ancestry individuals, 226 Native American ancestry individuals NA Illumina [26566045] (imputed) 26 QRS duration http://www.ebi.ac.uk/efo/EFO_0005055 GCST008054 Genome-wide genotyping array 17046 2019-07-02 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. C-reactive protein levels 8,349 African American individuals, 15,912 Hispanic/Latino individuals, 1,811 Asian ancestry individuals, 1,777 Native Hawaiian ancestry individuals, 574 Native American ancestry individuals, 97 individuals NA Illumina [30861016] (imputed) 45 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST008055 Genome-wide genotyping array 28520 2019-12-09 31379025 Sugier PE 2019-08-04 Clin Exp Allergy www.ncbi.nlm.nih.gov/pubmed/31379025 Genome-wide interaction study of early-life smoking exposure on time-to-asthma onset in childhood. Asthma (time to childhood onset) in early life tobacco smoke exposure 3,187 European ancestry individuals NA Illumina [2110000] (imputed) 1 childhood onset asthma, age at onset http://www.ebi.ac.uk/efo/EFO_0004591, http://www.ebi.ac.uk/efo/EFO_0004847 GCST009236 Genome-wide genotyping array 3187 2019-12-09 31379025 Sugier PE 2019-08-04 Clin Exp Allergy www.ncbi.nlm.nih.gov/pubmed/31379025 Genome-wide interaction study of early-life smoking exposure on time-to-asthma onset in childhood. Asthma (childhood onset) 5,086 European ancestry individuals NA Illumina [2110000] (imputed) 1 childhood onset asthma, age at onset http://www.ebi.ac.uk/efo/EFO_0004591, http://www.ebi.ac.uk/efo/EFO_0004847 GCST009237 Genome-wide genotyping array 5086 2019-12-09 31379025 Sugier PE 2019-08-04 Clin Exp Allergy www.ncbi.nlm.nih.gov/pubmed/31379025 Genome-wide interaction study of early-life smoking exposure on time-to-asthma onset in childhood. Asthma (time to childhood onset) x early life tobacco smoke interaction 3,187 European ancestry exposed individuals, 5,086 European ancestry unexposed individuals NA Illumina [2110000] (imputed) 4 childhood onset asthma, age at onset, environmental tobacco smoke exposure measurement http://www.ebi.ac.uk/efo/EFO_0004591, http://www.ebi.ac.uk/efo/EFO_0004847, http://www.ebi.ac.uk/efo/EFO_0008361 GCST009238 Genome-wide genotyping array 8273 2019-07-01 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Body mass index 17,127 African American individuals, 21,955 Hispanic/Latino individuals, 4,647 Asian ancestry individuals, 3,936 Native Hawaiian ancestry individuals, 645 Native American ancestry individuals, 1,025 individuals NA Illumina [32062178] (imputed) 63 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST008025 Genome-wide genotyping array 49335 2019-07-01 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Chronic kidney disease 1,533 African American cases, 1,339 Hispanic/Latino cases, 575 Asian ancestry cases, 608 Native Hawaiian ancestry cases, 42 Native American ancestry cases, 57 cases, 13,989 African American controls, 19,581 Hispanic/Latino controls, 3,549 Asian ancestry controls, 2,892 Native Hawaiian ancestry controls, 597 Native American ancestry controls, 965 controls NA Illumina [17780322] (imputed) 0 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST008026 Genome-wide genotyping array 45727 2019-07-01 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Smoking behaviour (cigarettes smoked per day) 7,171 African American individuals, 4,198 Hispanic/Latino individuals, 1,918 Asian ancestry individuals, 2,176 Native Hawaiian ancestry individuals, 288 Native American ancestry individuals, 111 individuals NA Illumina [27957689] (imputed) 5 cigarettes per day measurement http://www.ebi.ac.uk/efo/EFO_0006525 GCST008027 Genome-wide genotyping array 15862 2019-07-01 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Coffee consumption (cups per day) 11,862 African American individuals, 15,837 Hispanic/Latino individuals, 3,764 Asian ancestry individuals, 3,857 Native Hawaiian ancestry individuals, 582 Native American ancestry individuals NA Illumina [32504442] (imputed) 16 cups of coffee per day measurement http://www.ebi.ac.uk/efo/EFO_0006782 GCST008028 Genome-wide genotyping array 35902 2019-07-01 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Diastolic blood pressure 11,380 African American individuals, 21,549 Hispanic/Latino individuals, 1,086 Asian ancestry individuals, 636 Native American ancestry individuals, 782 individuals NA Illumina [32101933] (imputed) 13 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST008029 Genome-wide genotyping array 35433 2019-07-01 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Estimated glomerular filtration rate 8,261 African American individuals, 18,548 Hispanic/Latino individuals, 150 Asian ancestry individuals, 602 Native American ancestry individuals, 339 individuals NA Illumina [30341014] (imputed) 9 glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0005208 GCST008030 Genome-wide genotyping array 27900 2019-07-01 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. End-stage renal disease 326 African American cases, 208 Hispanic/Latino cases, 24 Asian ancestry cases, 21 Native Hawaiian ancestry cases, 1 Native American ancestry case, 22 cases, 8,739 African American controls, 16,197 Hispanic/Latino controls, 3,576 Asian ancestry controls, 2,925 Native Hawaiian ancestry controls, 52 Native American ancestry controls, 970 controls NA Illumina [11665604] (imputed) 0 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST008031 Genome-wide genotyping array 33061 2019-07-01 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Fasting blood glucose 6,457 African American individuals, 13,556 Hispanic/Latino individuals, 1,918 Asian ancestry individuals, 1,400 Native Hawaiian ancestry individuals, 412 Native American ancestry individuals, 168 individuals NA Illumina [29713514] (imputed) 28 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST008032 Genome-wide genotyping array 23911 2019-07-01 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Fasting blood insulin 5,525 African American individuals, 12,687 Hispanic/Latino individuals, 1,547 Asian ancestry individuals, 1,397 Native Hawaiian ancestry individuals, 395 Native American ancestry individuals NA Illumina [28840767] (imputed) 6 fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004466 GCST008033 Genome-wide genotyping array 21551 2019-07-01 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Hemoglobin A1c levels 559 African American individuals, 10,408 Hispanic/Latino individuals, 92 Asian ancestry individuals, 4 Native American ancestry individuals, 115 individuals NA Illumina [22871999] (imputed) 20 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST008034 Genome-wide genotyping array 11178 2019-07-01 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. High density lipoprotein cholesterol levels 10,085 African American individuals, 17,751 Hispanic/Latino individuals, 2,378 Asian ancestry individuals, 1,912 Native Hawaiian ancestry individuals, 604 Native American ancestry individuals, 333 individuals NA Illumina [31978362] (imputed) 153 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST008035 Genome-wide genotyping array 33063 2019-07-01 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Hypertension 11,863 African American cases, 8,663 Hispanic/Latino cases, 3,102 Asian ancestry cases, 2,645 Native Hawaiian ancestry cases, 342 Native American ancestry cases, 508 cases, 5,289 African American controls, 13,273 Hispanic/Latino controls, 1,561 Asian ancestry controls, 1,060 Native Hawaiian ancestry controls, 293 Native American ancestry controls, 542 controls NA Illumina [28263875] (imputed) 2 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST008036 Genome-wide genotyping array 49141 2019-07-01 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Low density lipoprotein cholesterol levels 9,720 African American individuals, 17,373 Hispanic/Latino individuals, 2,316 Asian ancestry individuals, 1,900 Native Hawaiian ancestry individuals, 591 Native American ancestry individuals, 321 individuals NA Illumina [31808917] (imputed) 131 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST008037 Genome-wide genotyping array 32221 2019-07-01 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Mean corpuscular hemoglobin concentration 3,750 African American individuals, 15,522 Hispanic/Latino individuals, 128 Asian ancestry individuals, 20 Native American ancestry individuals, 383 individuals NA Illumina [27815891] (imputed) 16 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST008038 Genome-wide genotyping array 19803 2019-07-01 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Platelet count 8,850 African American individuals, 18,949 Hispanic/Latino individuals, 541 Asian ancestry individuals, 603 Native American ancestry individuals, 385 individuals NA Illumina [30743395] (imputed) 36 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST008039 Genome-wide genotyping array 29328 2019-07-02 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. PR interval 3,360 African American individuals, 13,702 Hispanic/Latino individuals, 129 Asian ancestry individuals, 231 Native American ancestry individuals NA Illumina [26703325] (imputed) 31 PR interval http://www.ebi.ac.uk/efo/EFO_0004462 GCST008042 Genome-wide genotyping array 17422 2019-07-02 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. QT interval 3,293 African American individuals, 13,698 Hispanic/Latino individuals, 127 Asian ancestry individuals, 230 Native American ancestry individuals NA Illumina [26659972] (imputed) 51 QT interval http://www.ebi.ac.uk/efo/EFO_0004682 GCST008043 Genome-wide genotyping array 17348 2019-07-02 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Systolic blood pressure 11,380 African American individuals, 21,549 Hispanic/Latino individuals, 1,086 Asian ancestry individuals, 636 Native American ancestry individuals, 782 individuals NA Illumina [32101933] (imputed) 13 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST008044 Genome-wide genotyping array 35433 2019-07-02 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Total cholesterol levels 10,137 African American individuals, 17,802 Hispanic/Latino individuals, 2,387 Asian ancestry individuals, 1,915 Native Hawaiian ancestry individuals, 604 Native American ancestry individuals, 340 individuals NA Illumina [32003504] (imputed) 170 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST008045 Genome-wide genotyping array 33185 2019-07-02 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Triglyceride levels 9,980 African American individuals, 17,856 Hispanic/Latino individuals, 2,381 Asian ancestry individuals, 1,915 Native Hawaiian ancestry individuals, 604 Native American ancestry individuals, 360 individuals NA Illumina [31978265] (imputed) 137 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST008046 Genome-wide genotyping array 33096 2019-07-02 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Type 2 diabetes 5,971 African American cases, 4,135 Hispanic/Latino cases, 2,004 Asian ancestry cases, 1,534 Native Hawaiian ancestry cases, 167 Native American ancestry cases, 231 cases, 9,630 African American controls, 16,345 Hispanic/Latino controls, 2,572 Asian ancestry controls, 2,017 Native Hawaiian ancestry controls, 452 Native American ancestry controls, 667 controls NA Illumina [24011241] (imputed) 2 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST008048 Genome-wide genotyping array 45725 2019-07-02 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. White blood cell count 8,825 African American individuals, 18,251 Hispanic/Latino individuals, 543 Asian ancestry individuals, 606 Native American ancestry individuals, 383 individuals NA Illumina [30613845] (imputed) 47 leukocyte count http://www.ebi.ac.uk/efo/EFO_0004308 GCST008049 Genome-wide genotyping array 28608 2019-07-02 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Waist-hip ratio 9,140 African American females, 11,555 Hispanic/Latino females, 1,843 Asian ancestry females, 1,715 Native Hawaiian ancestry females, 585 Native American ancestry females NA Illumina [30305130] (imputed) 12 waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0004343 GCST008050 Genome-wide genotyping array 24838 2019-07-02 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Waist-hip ratio 1,146 African American males, 4,917 Hispanic/Latino males, 1,657 Asian ancestry males, 1,346 Native Hawaiian ancestry males NA Illumina [21894105] (imputed) 2 waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0004343 GCST008051 Genome-wide genotyping array 9066 2019-07-02 31217584 Wojcik GL 2019-06-19 Nature www.ncbi.nlm.nih.gov/pubmed/31217584 Genetic analyses of diverse populations improves discovery for complex traits. Waist-hip ratio 10,286 African American individuals, 16,472 Hispanic/Latino individuals, 3,500 Asian ancestry individuals, 3,061 Native Hawaiian ancestry individuals, 585 Native American ancestry individuals NA Illumina [at least 21894105] (imputed) 11 waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0004343 GCST008052 Genome-wide genotyping array 33904 2018-10-31 30177863 Maguire LH 2018-09-03 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30177863 Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease. Diverticular disease 27,444 British ancestry cases, 382,284 British ancestry controls NA Affymetrix [> 30000000] (imputed) 153 diverticular disease http://www.ebi.ac.uk/efo/EFO_0009959 GCST006479 Genome-wide genotyping array 409728 2020-02-19 31855235 McComish BJ 2019-12-19 JAMA Ophthalmol www.ncbi.nlm.nih.gov/pubmed/31855235 Association of Genetic Variation With Keratoconus. Keratoconus 522 European ancestry cases, 655 European ancestry controls 818 European ancestry cases, 3,858 European ancestry controls Illumina [6252612] (imputed) 3 Keratoconus http://www.orpha.net/ORDO/Orphanet_156071 GCST009677 Genome-wide genotyping array 1177 2019-11-20 31125052 Green HD 2019-05-24 J Crohns Colitis www.ncbi.nlm.nih.gov/pubmed/31125052 Genome-wide association study of microscopic colitis in the UK Biobank confirms immune-related pathogenesis. Microscopic colitis in proton-pump inhibitor treatment up to 98 European ancestry cases, up to 46,397 European ancestry controls NA Affymetrix [~ 12000000] (imputed) 0 microscopic colitis, response to proton-pump inhibitor http://www.ebi.ac.uk/efo/EFO_1001295, http://www.ebi.ac.uk/efo/EFO_0010235 GCST009080 Genome-wide genotyping array 46495 2019-11-20 31125052 Green HD 2019-05-24 J Crohns Colitis www.ncbi.nlm.nih.gov/pubmed/31125052 Genome-wide association study of microscopic colitis in the UK Biobank confirms immune-related pathogenesis. Microscopic colitis 423 European ancestry cases, 445,232 European ancestry controls NA Affymetrix [~ 12000000] (imputed) 24 microscopic colitis http://www.ebi.ac.uk/efo/EFO_1001295 GCST009081 Genome-wide genotyping array 445655 2018-06-05 29760442 Iglesias AI 2018-05-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29760442 Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases. Central corneal thickness 17,803 European ancestry individuals, 8,107 Asian ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 46 central corneal thickness http://www.ebi.ac.uk/efo/EFO_0005213 GCST005667 Genome-wide genotyping array 25910 2018-09-27 29760442 Iglesias AI 2018-05-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29760442 Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases. Central corneal thickness 17,803 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 14 central corneal thickness http://www.ebi.ac.uk/efo/EFO_0005213 GCST006366 Genome-wide genotyping array 17803 2018-09-27 29760442 Iglesias AI 2018-05-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29760442 Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases. Central corneal thickness 8,107 Asian ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 1 central corneal thickness http://www.ebi.ac.uk/efo/EFO_0005213 GCST006367 Genome-wide genotyping array 8107 2018-08-03 29767774 Lutz SM 2018-05-15 Nicotine Tob Res www.ncbi.nlm.nih.gov/pubmed/29767774 Common and rare variants genetic association analysis of cigarettes per day among ever smokers in COPD cases and controls. Current cigarettes per day in chronic obstructive pulmonary disease 2,812 European ancestry cases, 3,846 European ancestry controls, 821 African American cases, 2,459 African American controls 2,627 cases, 986 controls Illumina [NR] 2 smoking behaviour measurement http://www.ebi.ac.uk/efo/EFO_0005671 GCST006042 Genome-wide genotyping array 9938 2020-02-13 31748543 Johnston KJA 2019-11-20 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31748543 Identification of novel common variants associated with chronic pain using conditional false discovery rate analysis with major depressive disorder and assessment of pleiotropic effects of LRFN5. Chronic pain or major depressive disorder (pleiotropy) 10,543 European ancestry chronic pain cases, 43,028 major depressive disorder cases, 12,758 European ancestry controls, 87,522 controls NA NR [774292] 0 unipolar depression, Chronic pain http://www.ebi.ac.uk/efo/EFO_0003761, http://purl.obolibrary.org/obo/HP_0012532 GCST009607 Genome-wide genotyping array 153851 2018-07-04 29558500 Lee J 2018-03-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/29558500 Genome-wide association analysis identifies multiple loci associated with kidney disease-related traits in Korean populations. Creatinine levels 7,064 Korean ancestry individuals 6,509 Korean ancestry individuals Affymetrix [345072] 0 creatinine measurement http://www.ebi.ac.uk/efo/EFO_0004518 GCST005791 Genome-wide genotyping array 7064 2018-07-04 29558500 Lee J 2018-03-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/29558500 Genome-wide association analysis identifies multiple loci associated with kidney disease-related traits in Korean populations. Glomerular filtration rate 7,064 Korean ancestry individuals 6,509 Korean ancestry individuals Affymetrix [345072] 0 glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0005208 GCST005792 Genome-wide genotyping array 7064 2018-07-04 29558500 Lee J 2018-03-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/29558500 Genome-wide association analysis identifies multiple loci associated with kidney disease-related traits in Korean populations. Uric acid levels 7,064 Korean ancestry individuals 3,703 Korean ancestry individuals Affymetrix [345072] 6 uric acid measurement http://www.ebi.ac.uk/efo/EFO_0004761 GCST005793 Genome-wide genotyping array 7064 2018-07-04 29558500 Lee J 2018-03-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/29558500 Genome-wide association analysis identifies multiple loci associated with kidney disease-related traits in Korean populations. Blood urea nitrogen levels 7,064 Korean ancestry individuals 6,509 Korean ancestry individuals Affymetrix [345072] 1 blood urea nitrogen measurement http://www.ebi.ac.uk/efo/EFO_0004741 GCST005794 Genome-wide genotyping array 7064 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Dysmenorrheic pain severity 5,734 Japanese ancestry female individuals 5,614 Japanese ancestry female individuals Affymetrix [536506] 5 dysmenorrheic pain measurement http://www.ebi.ac.uk/efo/EFO_0007889 GCST006656 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Menstruation quality of life impact (dysmenorrhea) 3,573 Japanese ancestry female cases, 2,161 Japanese ancestry female controls 3,580 Japanese ancestry female cases, 2,034 Japanese ancestry female controls Affymetrix [536506] 8 quality of life during menstruation measurement, dysmenorrheic pain measurement http://www.ebi.ac.uk/efo/EFO_0009366, http://www.ebi.ac.uk/efo/EFO_0007889 GCST006636 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Pain medicine use during menstruation 1,813 Japanese ancestry female cases, 3,921 Japanese ancestry female controls 1,494 Japanese ancestry female cases, 4,120 Japanese ancestry female controls Affymetrix [536506] 7 drug use measurement, quality of life during menstruation measurement http://www.ebi.ac.uk/efo/EFO_0007010, http://www.ebi.ac.uk/efo/EFO_0009366 GCST006637 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Menstruation quality of life impact (fever) 112 Japanese ancestry female cases, 5,622 Japanese ancestry female controls 157 Japanese ancestry female cases, 5,457 Japanese ancestry female controls Affymetrix [536506] 2 quality of life during menstruation measurement, Fever http://www.ebi.ac.uk/efo/EFO_0009366, http://purl.obolibrary.org/obo/HP_0001945 GCST006638 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Heavy vaginal discharge 457 Japanese ancestry female cases, 5,277 Japanese ancestry female controls 471 Japanese ancestry female cases, 5,143 Japanese ancestry female controls Affymetrix [536506] 3 quality of life during menstruation measurement, vaginal discharge http://www.ebi.ac.uk/efo/EFO_0009366, http://www.ebi.ac.uk/efo/EFO_0009365 GCST006639 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Menstruation quality of life impact (acne) 1,115 Japanese ancestry female cases, 4,619 Japanese ancestry female controls 1,204 Japanese ancestry female cases, 4,410 Japanese ancestry female controls Affymetrix [536506] 8 quality of life during menstruation measurement, acne http://www.ebi.ac.uk/efo/EFO_0009366, http://www.ebi.ac.uk/efo/EFO_0003894 GCST006640 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Menstruation quality of life impact (aggressiveness) 899 Japanese ancestry female cases, 4,835 Japanese ancestry female controls 1,030 Japanese ancestry female cases, 4,584 Japanese ancestry female controls Affymetrix [536506] 5 quality of life during menstruation measurement, aggressive behavior http://www.ebi.ac.uk/efo/EFO_0009366, http://www.ebi.ac.uk/efo/EFO_0003015 GCST006641 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Menstruation quality of life impact (increased appetite) 760 Japanese ancestry female cases, 4,974 Japanese ancestry female controls 903 Japanese ancestry female cases, 4,711 Japanese ancestry female controls Affymetrix [536506] 3 quality of life during menstruation measurement, eating behaviour http://www.ebi.ac.uk/efo/EFO_0009366, http://www.ebi.ac.uk/efo/EFO_0007829 GCST006642 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Menstruation quality of life impact (bowel movement) 903 Japanese ancestry female cases, 4,831 Japanese ancestry female controls 921 Japanese ancestry female cases, 4,693 Japanese ancestry female controls Affymetrix [536506] 5 quality of life during menstruation measurement, Abnormal peristalsis http://www.ebi.ac.uk/efo/EFO_0009366, http://purl.obolibrary.org/obo/HP_0030914 GCST006643 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Menstruation quality of life impact (depression) 1,863 Japanese ancestry female cases, 3,871 Japanese ancestry female controls 2,005 Japanese ancestry female cases, 3,609 Japanese ancestry female controls Affymetrix [536506] 1 quality of life during menstruation measurement, unipolar depression http://www.ebi.ac.uk/efo/EFO_0009366, http://www.ebi.ac.uk/efo/EFO_0003761 GCST006644 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Menstruation quality of life impact (edema) 1,109 Japanese ancestry female cases, 4,625 Japanese ancestry female controls 1,331 Japanese ancestry female cases, 4,283 Japanese ancestry female controls Affymetrix [536506] 3 quality of life during menstruation measurement, edema http://www.ebi.ac.uk/efo/EFO_0009366, http://www.ebi.ac.uk/efo/EFO_0009373 GCST006645 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Menstruation quality of life impact (headache) 1,758 Japanese ancestry female cases, 3,976 Japanese ancestry female controls 1,763 Japanese ancestry female cases, 3,851 Japanese ancestry female controls Affymetrix [536506] 4 quality of life during menstruation measurement, Headache http://www.ebi.ac.uk/efo/EFO_0009366, http://purl.obolibrary.org/obo/HP_0002315 GCST006646 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Menstruation quality of life impact (joint pain) 251 Japanese ancestry female cases, 5,483 Japanese ancestry female controls 277 Japanese ancestry female cases, 5,337 Japanese ancestry female controls Affymetrix [536506] 4 quality of life during menstruation measurement, Arthralgia http://www.ebi.ac.uk/efo/EFO_0009366, http://purl.obolibrary.org/obo/HP_0002829 GCST006647 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Menstruation quality of life impact (loss of concentration) 995 Japanese ancestry female cases, 4,739 Japanese ancestry female controls 1,081 Japanese ancestry female cases, 4,533 Japanese ancestry female controls Affymetrix [536506] 8 quality of life during menstruation measurement, decreased attention http://www.ebi.ac.uk/efo/EFO_0009366, http://purl.obolibrary.org/obo/NCIT_C117245 GCST006648 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Menstruation quality of life impact (nervousness) 1,904 Japanese ancestry female cases, 3,830 Japanese ancestry female controls 2,017 Japanese ancestry female cases, 3,597 Japanese ancestry female controls Affymetrix [536506] 2 nervousness, quality of life during menstruation measurement http://purl.obolibrary.org/obo/NCIT_C74532, http://www.ebi.ac.uk/efo/EFO_0009366 GCST006649 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Menstruation quality of life impact (pressure in breast) 642 Japanese ancestry female cases, 5,092 Japanese ancestry female controls 667 Japanese ancestry female cases, 4,947 Japanese ancestry female controls Affymetrix [536506] 4 quality of life during menstruation measurement, breast pressure measurement http://www.ebi.ac.uk/efo/EFO_0009366, http://www.ebi.ac.uk/efo/EFO_0009393 GCST006650 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Menstruation quality of life impact (sleepiness) 1,902 Japanese ancestry female cases, 3,832 Japanese ancestry female controls 1,934 Japanese ancestry female cases, 3,680 Japanese ancestry female controls Affymetrix [536506] 3 quality of life during menstruation measurement, sleepiness http://www.ebi.ac.uk/efo/EFO_0009366, http://purl.obolibrary.org/obo/NCIT_C95746 GCST006651 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Menstruation quality of life impact (stiff neck) 937 Japanese ancestry female cases, 4,797 Japanese ancestry female controls 944 Japanese ancestry female cases, 4,670 Japanese ancestry female controls Affymetrix [536506] 4 quality of life during menstruation measurement, Stiff neck http://www.ebi.ac.uk/efo/EFO_0009366, http://purl.obolibrary.org/obo/HP_0025258 GCST006652 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Vaginal discharge (itching) 676 Japanese ancestry female cases, 5,058 Japanese ancestry female controls 669 Japanese ancestry female cases, 4,945 Japanese ancestry female controls Affymetrix [536506] 5 abnormal vaginal discharge itching http://www.ebi.ac.uk/efo/EFO_0009409 GCST006653 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Vaginal discharge (metrorrhagia) 406 Japanese ancestry female cases, 5,328 Japanese ancestry female controls 302 Japanese ancestry female cases, 5,312 Japanese ancestry female controls Affymetrix [536506] 2 vaginal discharge, Metrorrhagia http://www.ebi.ac.uk/efo/EFO_0009365, http://purl.obolibrary.org/obo/HP_0100608 GCST006657 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Vaginal discharge (smell) 367 Japanese ancestry female cases, 5,367 Japanese ancestry female controls 392 Japanese ancestry female cases, 5,222 Japanese ancestry female controls Affymetrix [536506] 5 abnormal vaginal discharge smell http://www.ebi.ac.uk/efo/EFO_0009408 GCST006654 Genome-wide genotyping array 5734 2018-11-30 29855537 Hirata T 2018-05-31 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29855537 Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. Breast size 5,609 Japanese ancestry female individuals NA Affymetrix [536506] 11 breast size http://www.ebi.ac.uk/efo/EFO_0004884 GCST006655 Genome-wide genotyping array 5609 2018-10-17 29971594 Rosenberger A 2018-07-03 Int Arch Occup Environ Health www.ncbi.nlm.nih.gov/pubmed/29971594 Genetic modifiers of radon-induced lung cancer risk: a genome-wide interaction study in former uranium miners. Lung cancer x radon exposure interaction (1df) 49 European ancestry high radon exposure cases, 15,028 European ancestry low radon exposure cases, 259 European ancestry high radon exposure controls, 13,263 European ancestry low radon exposure controls NA Illumina [407117] 3 lung carcinoma, radon exposure measurement http://www.ebi.ac.uk/efo/EFO_0001071, http://www.ebi.ac.uk/efo/EFO_0009370 GCST006413 Genome-wide genotyping array 28599 2019-12-16 31591465 Bigdeli TB 2019-10-07 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/31591465 Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry. Schizophrenia or schizoaffective disorder 6,152 African ancestry cases, 1,234 Latino cases, 34,241 European and East Asian ancestry cases, 3,918 African ancestry controls, 3,090 Latino controls, 45,604 European and East Asian ancestry controls, 1,235 European ancestry trios NA Illumina [NR] (imputed) 3 schizophrenia, schizoaffective disorder http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0005411 GCST009283 Genome-wide genotyping array 95474 2018-08-15 29895819 Endo C 2018-06-12 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29895819 Genome-wide association study in Japanese females identifies fifteen novel skin-related trait associations. Freckles 7,148 Japanese ancestry female cases, 4,034 Japanese ancestry female controls NA Affymetrix [536506] 7 freckles http://www.ebi.ac.uk/efo/EFO_0003963 GCST006091 Genome-wide genotyping array 11182 2018-08-15 29895819 Endo C 2018-06-12 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29895819 Genome-wide association study in Japanese females identifies fifteen novel skin-related trait associations. Double-edged eyelids 2,069 Japanese ancestry female cases, 3,545 Japanese ancestry female controls NA Affymetrix [536506] 2 eye morphology measurement http://www.ebi.ac.uk/efo/EFO_0007858 GCST006092 Genome-wide genotyping array 5614 2018-08-15 29895819 Endo C 2018-06-12 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29895819 Genome-wide association study in Japanese females identifies fifteen novel skin-related trait associations. Thick vs thin eyebrows 1,153 Japanese ancestry female thick eyebrow individuals, 2,788 Japanese ancestry female thin eyebrow individuals NA Affymetrix [536506] 1 facial hair thickness measurement http://www.ebi.ac.uk/efo/EFO_0007823 GCST006093 Genome-wide genotyping array 3941 2018-08-15 29895819 Endo C 2018-06-12 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29895819 Genome-wide association study in Japanese females identifies fifteen novel skin-related trait associations. Straight vs curly hair 2,532 Japanese ancestry female straight hair individuals, 2,346 Japanese ancestry female curly hair individuals NA Affymetrix [536506] 1 hair morphology measurement http://www.ebi.ac.uk/efo/EFO_0007821 GCST006094 Genome-wide genotyping array 4878 2018-08-15 29895819 Endo C 2018-06-12 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29895819 Genome-wide association study in Japanese females identifies fifteen novel skin-related trait associations. Excessive hairiness 3,830 Japanese ancestry female cases, 7,414 Japanese ancestry female controls NA Affymetrix [536506] 6 Hirsutism http://purl.obolibrary.org/obo/HP_0001007 GCST006095 Genome-wide genotyping array 11244 2018-08-15 29895819 Endo C 2018-06-12 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29895819 Genome-wide association study in Japanese females identifies fifteen novel skin-related trait associations. Excessive sweating 1,245 Japanese ancestry female cases, 3,293 Japanese ancestry female controls NA Affymetrix [536506] 3 Hyperhidrosis http://purl.obolibrary.org/obo/HP_0000975 GCST006090 Genome-wide genotyping array 4538 2018-08-15 29895819 Endo C 2018-06-12 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29895819 Genome-wide association study in Japanese females identifies fifteen novel skin-related trait associations. Age spots 3,815 Japanese ancestry female cases, 7,438 Japanese ancestry female controls NA Affymetrix [536506] 3 solar lentigines measurement http://www.ebi.ac.uk/efo/EFO_0007850 GCST006096 Genome-wide genotyping array 11253 2018-09-14 29967481 Joo YB 2018-07-02 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29967481 Genetic variants in systemic lupus erythematosus susceptibility loci, XKR6 and GLT1D1 are associated with childhood-onset SLE in a Korean cohort. Childhood onset systemic lupus erythematosus 96 Korean ancestry childhood onset cases, 685 Korean ancestry adult onset cases NA Illumina [648077] 2 age at onset, systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0004847, http://www.ebi.ac.uk/efo/EFO_0002690 GCST006260 Genome-wide genotyping array 781 2020-02-18 31666285 Olafsson S 2019-10-30 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/31666285 Common and rare sequence variants influencing tumor biomarkers in blood. Serum alpha-fetoprotein levels 22,686 Icelandic ancestry individuals NA Illumina [NR] (imputed) 3 alpha fetoprotein measurement http://www.ebi.ac.uk/efo/EFO_0010583 GCST009651 Genome-wide genotyping array 22686 2020-02-18 31666285 Olafsson S 2019-10-30 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/31666285 Common and rare sequence variants influencing tumor biomarkers in blood. Serum carcinoembryonic antigen levels 22,309 Icelandic ancestry individuals NA Illumina [NR] (imputed) 11 serum carcinoembryonic antigen measurement http://www.ebi.ac.uk/efo/EFO_0005760 GCST009650 Genome-wide genotyping array 22309 2020-02-18 31666285 Olafsson S 2019-10-30 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/31666285 Common and rare sequence variants influencing tumor biomarkers in blood. Serum cancer antigen 15.3 levels 7,107 Icelandic ancestry individuals NA Illumina [NR] (imputed) 6 cancer antigen 15.3 measurement http://www.ebi.ac.uk/efo/EFO_0010585 GCST009649 Genome-wide genotyping array 7107 2020-02-18 31666285 Olafsson S 2019-10-30 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/31666285 Common and rare sequence variants influencing tumor biomarkers in blood. Serum cancer antigen 19.9 levels 9,945 Icelandic ancestry individuals NA Illumina [NR] (imputed) 4 cancer antigen 19.9 measurement http://www.ebi.ac.uk/efo/EFO_0010584 GCST009648 Genome-wide genotyping array 9945 2020-02-18 31666285 Olafsson S 2019-10-30 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/31666285 Common and rare sequence variants influencing tumor biomarkers in blood. Serum cancer antigen 125 levels 9,824 Icelandic ancestry individuals NA Illumina [NR] (imputed) 9 cancer antigen 125 measurement http://www.ebi.ac.uk/efo/EFO_0010603 GCST009647 Genome-wide genotyping array 9824 2020-02-18 31666285 Olafsson S 2019-10-30 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/31666285 Common and rare sequence variants influencing tumor biomarkers in blood. Serum alkaline phosphatase levels 162,774 Icelandic ancestry individuals NA Illumina [NR] (imputed) 50 alkaline phosphatase measurement http://www.ebi.ac.uk/efo/EFO_0004533 GCST009652 Genome-wide genotyping array 162774 2020-04-21 32107650 Liu L 2020-02-27 Clin Transl Med www.ncbi.nlm.nih.gov/pubmed/32107650 A trans-ethnic two-stage polygenetic scoring analysis detects genetic correlation between osteoporosis and schizophrenia. Schizophrenia (MTAG) 1,627 Han Chinese ancestry individuals with osteoporosis-related bone measurements, 1,475 Han Chinese ancestry schizophrenia cases, 1,022 Han Chinese ancestry schizophrenia controls NA Affymetrix [NR] 4 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST009891 Genome-wide genotyping array 4124 2020-04-21 32107650 Liu L 2020-02-27 Clin Transl Med www.ncbi.nlm.nih.gov/pubmed/32107650 A trans-ethnic two-stage polygenetic scoring analysis detects genetic correlation between osteoporosis and schizophrenia. Osteoporosis-related phenotypes (MTAG) 1,627 Han Chinese ancestry individuals with osteoporosis-related bone measurements, 1,475 Han Chinese ancestry schizophrenia cases, 1,022 Han Chinese ancestry schizophrenia controls NA Affymetrix [NR] 7 bone measurement http://www.ebi.ac.uk/efo/EFO_0004512 GCST009892 Genome-wide genotyping array 4124 2020-04-21 25569235 Demirkan A 2015-01-08 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/25569235 Insight in genome-wide association of metabolite quantitative traits by exome sequence analyses. Serum metabolite levels 2,118 Erasmus Rucphen (founder/genetic isolate) individuals NA Illumina [~ 2500000] (imputed) 9 serum metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005653 GCST009893 Genome-wide genotyping array 2118 2020-04-30 26407342 Loukola A 2015-09-25 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/26407342 A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism. Nicotine metabolite ratio in current smokers 1,518 Finnish ancestry individuals NA Illumina [8970401] (imputed) 3 nicotine metabolite ratio http://www.ebi.ac.uk/efo/EFO_0007794 GCST009922 Genome-wide genotyping array 1518 2020-07-21 32185793 Yan J 2020-03-17 Clin Genet www.ncbi.nlm.nih.gov/pubmed/32185793 A genome-wide association study identifies FSHR rs2300441 associated with follicle-stimulating hormone levels. Follicle stimulating hormone levels 2,590 Han Chinese ancestry individuals NA Affymetrix [3101376] (imputed) 5 follicle stimulating hormone measurement http://www.ebi.ac.uk/efo/EFO_0004768 GCST010265 Genome-wide genotyping array 2590 2020-07-21 32185793 Yan J 2020-03-17 Clin Genet www.ncbi.nlm.nih.gov/pubmed/32185793 A genome-wide association study identifies FSHR rs2300441 associated with follicle-stimulating hormone levels. Follicle stimulating hormone in healthy women 708 Han Chinese ancestry individuals NA Affymetrix [3101376] (imputed) 7 follicle stimulating hormone measurement http://www.ebi.ac.uk/efo/EFO_0004768 GCST010264 Genome-wide genotyping array 708 2020-07-21 32185793 Yan J 2020-03-17 Clin Genet www.ncbi.nlm.nih.gov/pubmed/32185793 A genome-wide association study identifies FSHR rs2300441 associated with follicle-stimulating hormone levels. Follicle stimulating hormone levels in polycystic ovary syndrome 1,882 Han Chinese ancestry individuals NA Affymetrix [3101376] (imputed) 4 follicle stimulating hormone measurement http://www.ebi.ac.uk/efo/EFO_0004768 GCST010263 Genome-wide genotyping array 1882 2020-07-21 32185793 Yan J 2020-03-17 Clin Genet www.ncbi.nlm.nih.gov/pubmed/32185793 A genome-wide association study identifies FSHR rs2300441 associated with follicle-stimulating hormone levels. Luteinizing hormone levels in polycystic ovary syndrome 1,882 Han Chinese ancestry individuals NA Affymetrix [3101376] (imputed) 0 luteinizing hormone measurement http://www.ebi.ac.uk/efo/EFO_0007002 GCST010262 Genome-wide genotyping array 1882 2020-07-21 32185793 Yan J 2020-03-17 Clin Genet www.ncbi.nlm.nih.gov/pubmed/32185793 A genome-wide association study identifies FSHR rs2300441 associated with follicle-stimulating hormone levels. Luteinizing hormone levels in healthy women 720 Han Chinese ancestry individuals NA Affymetrix [3101376] (imputed) 1 luteinizing hormone measurement http://www.ebi.ac.uk/efo/EFO_0007002 GCST010261 Genome-wide genotyping array 720 2020-07-21 32185793 Yan J 2020-03-17 Clin Genet www.ncbi.nlm.nih.gov/pubmed/32185793 A genome-wide association study identifies FSHR rs2300441 associated with follicle-stimulating hormone levels. Luteinizing hormone levels 2,590 Han Chinese ancestry individuals NA Affymetrix [3101376] (imputed) 0 luteinizing hormone measurement http://www.ebi.ac.uk/efo/EFO_0007002 GCST010260 Genome-wide genotyping array 2590 2020-06-17 32180562 Kulyte A 2020-01-25 Mol Metab www.ncbi.nlm.nih.gov/pubmed/32180562 Genome-wide association study of adipocyte lipolysis in the GENetics of adipocyte lipolysis (GENiAL) cohort. Spontaneous adipocyte lipolysis 856 European ancestry individuals NA NR [9260588] (imputed) 25 lipid measurement http://www.ebi.ac.uk/efo/EFO_0004529 GCST010088 Genome-wide genotyping array 856 2020-06-17 32180562 Kulyte A 2020-01-25 Mol Metab www.ncbi.nlm.nih.gov/pubmed/32180562 Genome-wide association study of adipocyte lipolysis in the GENetics of adipocyte lipolysis (GENiAL) cohort. Stimulated adipocyte lipolysis 874 European ancestry individuals NA NR [9260588] (imputed) 41 lipid measurement http://www.ebi.ac.uk/efo/EFO_0004529 GCST010087 Genome-wide genotyping array 874 2020-07-09 32184442 Olafsdottir T 2020-03-17 Commun Biol www.ncbi.nlm.nih.gov/pubmed/32184442 Genome-wide association identifies seven loci for pelvic organ prolapse in Iceland and the UK Biobank. Pelvic organ prolapse 15,010 European ancestry cases, 340,734 European ancestry controls NA Affymetrix, Illumina [37144863] (imputed) 12 pelvic organ prolapse http://www.ebi.ac.uk/efo/EFO_0004710 GCST010174 Genome-wide genotyping array, Genome-wide sequencing 355744 2020-01-10 31792237 Yang BZ 2019-12-02 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31792237 Genomewide Gene-by-Sex Interaction Scans Identify ADGRV1 for Sex Differences in Opioid Dependent African Americans. Opioid dependence x sex interaction 2,603 African American cases, 2,341 African American controls, 2,112 European ancestry cases, 1,331 European ancestry controls NA Illumina [up to 8775706] (imputed) 9 sex interaction measurement, opioid dependence http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0005611 GCST009419 Genome-wide genotyping array 8387 2020-01-21 31809533 Han X 2019-09-06 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/31809533 Genome-wide association analysis of 95 549 individuals identifies novel loci and genes influencing optic disc morphology. Optic disc size 67,040 British ancestry individuals 28,509 European ancestry individuals Affymetrix [8928767] (imputed) 115 optic disc size measurement http://www.ebi.ac.uk/efo/EFO_0004832 GCST009462 Genome-wide genotyping array 67040 2020-10-27 31811950 Penney KL 2019-12-04 Clin Gastroenterol Hepatol www.ncbi.nlm.nih.gov/pubmed/31811950 Genetic Variant Associated with Survival of Patients with Stage II-III Colon Cancer. Disease free survival in colon cancer 4,319 European ancestry cases, 358 African American cases, 190 Asian cases, 107 cases NA Illumina [873829] (imputed) 1 disease free survival http://www.ebi.ac.uk/efo/EFO_0000409 GCST010717 Genome-wide genotyping array 4974 2020-10-27 31811950 Penney KL 2019-12-04 Clin Gastroenterol Hepatol www.ncbi.nlm.nih.gov/pubmed/31811950 Genetic Variant Associated with Survival of Patients with Stage II-III Colon Cancer. Survival in colon cancer 4,319 European ancestry cases, 358 African American cases, 190 Asian cases, 107 cases NA Illumina [873829] (imputed) 1 overall survival http://www.ebi.ac.uk/efo/EFO_0000638 GCST010716 Genome-wide genotyping array 4974 2020-01-15 31792241 Gouveia MH 2019-12-02 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31792241 Genetics of cognitive trajectory in Brazilians: 15 years of follow-up from the Bambuí-Epigen Cohort Study of Aging. Cognitive decline (age-related) 1,407 Brazilian ancestry individuals NA Illumina [at least 2500000] (imputed) 13 cognitive decline measurement http://www.ebi.ac.uk/efo/EFO_0007710 GCST009433 Genome-wide genotyping array 1407 2018-09-06 29967566 Roberts CH 2018-06-03 Mediators Inflamm www.ncbi.nlm.nih.gov/pubmed/29967566 Pathway-Wide Genetic Risks in Chlamydial Infections Overlap between Tissue Tropisms: A Genome-Wide Association Scan. Anti-chlamydia trachomatis IgG seropositivity 71 Dutch ancestry cases, 169 Dutch ancestry controls NA Illumina [9443221] (imputed) 5 Chlamydia trachomatis seropositivity http://www.ebi.ac.uk/efo/EFO_0009330 GCST006225 Genome-wide genotyping array 240 2021-04-16 32881892 Lin SH 2020-09-03 PLoS One www.ncbi.nlm.nih.gov/pubmed/32881892 Low-frequency variation near common germline susceptibility loci are associated with risk of Ewing sarcoma. Ewing sarcoma 733 European ancestry cases, 1,346 European ancestry controls NA Illumina [16367531] (imputed) 3 Ewing sarcoma http://www.ebi.ac.uk/efo/EFO_0000174 GCST011498 Genome-wide genotyping array 2079 2021-04-09 32869517 Sung H 2020-08-31 Mol Genet Genomic Med www.ncbi.nlm.nih.gov/pubmed/32869517 Genome-wide association study of café-au-lait macule number in neurofibromatosis type 1. Café-au-lait macule number in neurofibromatosis type1 112 European ancestry individuals 59 European ancestry individuals Illumina [608561] 2 Cafe-au-lait spot http://purl.obolibrary.org/obo/HP_0000957 GCST011464 Genome-wide genotyping array 112 2021-04-16 32876488 Meeks KAC 2020-09-02 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/32876488 The Genetics of Circulating Resistin Level, A Biomarker for Cardiovascular Diseases, Is Informed by Mendelian Randomization and the Unique Characteristics of African Genomes. Resistin levels 3,754 Sub-Saharan African ancestry individuals, 1,867 African American individuals NA Affymetrix [NR] (imputed) 1 resistin measurement http://www.ebi.ac.uk/efo/EFO_0004819 GCST011497 Genome-wide genotyping array 5621 2021-03-22 32106291 Grunin M 2020-02-01 Invest Ophthalmol Vis Sci www.ncbi.nlm.nih.gov/pubmed/32106291 Association of a Variant in VWA3A with Response to Anti-Vascular Endothelial Growth Factor Treatment in Neovascular AMD. Response to anti-VEGF treatment in neovascular age-related macular degeneration (visual acuity) 187 Israeli ancestry individuals 108 Israeli ancestry individuals NR [5353842] (imputed) 0 age-related macular degeneration, response to anti-vascular endothelial growth factor drug http://www.ebi.ac.uk/efo/EFO_0001365, http://www.ebi.ac.uk/efo/EFO_0009467 GCST011376 Genome-wide genotyping array 187 2020-04-15 32066683 Lacaze P 2020-01-27 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32066683 Genetic associations with clozapine-induced myocarditis in patients with schizophrenia. Clozapine-induced myocarditis in schizophrenia 33 cases, 62 controls NA Illumina [6822414] (imputed) 4 myocarditis, response to clozapine http://www.ebi.ac.uk/efo/EFO_0009609, http://purl.obolibrary.org/obo/GO_0097338 GCST009817 Genome-wide genotyping array 95 2018-10-31 29942085 Nagel M 2018-06-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29942085 Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. Depression 688,809 European ancestry individuals NA Affymetrix [10847151] (imputed) 82 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST006477 Genome-wide genotyping array 688809 2018-10-31 29942085 Nagel M 2018-06-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29942085 Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. Depressed affect 357,957 European ancestry individuals NA Affymetrix [10847151] (imputed) 157 unipolar depression, mood disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0004247 GCST006475 Genome-wide genotyping array 357957 2018-10-31 29942085 Nagel M 2018-06-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29942085 Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. Worry 348,219 European ancestry individuals NA Affymetrix [10847151] (imputed) 147 worry measurement http://www.ebi.ac.uk/efo/EFO_0009589 GCST006478 Genome-wide genotyping array 348219 2018-10-31 29942085 Nagel M 2018-06-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29942085 Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. Neuroticism 449,484 European ancestry individuals NA Affymetrix [10847151] (imputed) 371 neuroticism measurement http://www.ebi.ac.uk/efo/EFO_0007660 GCST006476 Genome-wide genotyping array 449484 2020-06-25 25590795 Yazar S 2015-04-01 JAMA Ophthalmol www.ncbi.nlm.nih.gov/pubmed/25590795 Genetic and environmental factors in conjunctival UV autofluorescence. Conjunctival UV autofluorescence (CUVAF) 1,251 European ancestry individuals NA Illumina [5003381] (imputed) 5 eye measurement, sun exposure measurement http://www.ebi.ac.uk/efo/EFO_0004731, http://www.ebi.ac.uk/efo/EFO_0010729 GCST010106 Genome-wide genotyping array 1251 2018-08-14 29892016 Schumacher FR 2018-06-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29892016 Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. Prostate cancer aggressiveness (high vs low) 15,561 European ancestry high aggressive cases, 9,739 European ancestry low aggressive cases NA Illumina [20370935] (imputed) 0 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST006080 Genome-wide genotyping array 25300 2018-08-14 29892016 Schumacher FR 2018-06-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29892016 Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. Prostate cancer aggressiveness (high vs low/intermediate) 20,658 European ancestry high aggressive cases, 38,093 European ancestry low/intermediate aggressive cases NA Illumina [20370935] (imputed) 0 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST006082 Genome-wide genotyping array 58751 2018-08-14 29892016 Schumacher FR 2018-06-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29892016 Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. Prostate cancer (advanced vs non-advanced) 14,160 European ancestry advanced cases, 62,421 European ancestry non-advanced cases NA Illumina [20370935] (imputed) 0 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST006081 Genome-wide genotyping array 76581 2018-08-14 29892016 Schumacher FR 2018-06-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29892016 Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. Prostate cancer (advanced) 15,167 European ancestry cases, 58,308 European ancestry controls NA Illumina [20370935] (imputed) 18 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST006083 Genome-wide genotyping array 73475 2018-08-14 29892016 Schumacher FR 2018-06-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29892016 Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. Prostate cancer (early onset) 6,988 European ancestry cases, 44,256 European ancestry controls NA Illumina [20370935] (imputed) 11 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST006089 Genome-wide genotyping array 51244 2018-08-14 29892016 Schumacher FR 2018-06-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29892016 Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. Prostate cancer (Gleason score) 61,978 European ancestry cases NA Illumina [20370935] (imputed) 0 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST006084 Genome-wide genotyping array 61978 2018-08-14 29892016 Schumacher FR 2018-06-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29892016 Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. Prostate cancer 79,148 European ancestry cases, 61,106 European ancestry controls NA Illumina [20370935] (imputed) 140 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST006085 Genome-wide genotyping array 140254 2020-01-21 31786426 Farias Tempaku P 2019-08-14 Sleep Med www.ncbi.nlm.nih.gov/pubmed/31786426 Genome-wide association study reveals two novel risk alleles for incident obstructive sleep apnea in the EPISONO cohort. Obstructive sleep apnea trait (apnea hypopnea index, change over time) 404 European ancestry individuals, 97 Black individuals, 20 Asian ancestry individuals, 20 Indigenous individuals, 138 mixed race individuals, 27 individuals NA Illumina [up to 730525] 25 sleep apnea measurement http://www.ebi.ac.uk/efo/EFO_0007817 GCST009461 Genome-wide genotyping array 706 2021-06-03 31797917 Ward J 2019-12-04 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31797917 Novel genome-wide associations for anhedonia, genetic correlation with psychiatric disorders, and polygenic association with brain structure. Anhedonia 375,724 European ancestry individuals 93,559 individuals Affymetrix [NR] 0 anhedonia measurement http://www.ebi.ac.uk/efo/EFO_0009587 GCST011778 Genome-wide genotyping array 375724 2018-08-24 28838971 Mercader JM 2017-08-24 Diabetes www.ncbi.nlm.nih.gov/pubmed/28838971 A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes. Type 2 diabetes 4,052 Hispanic cases and 4,606 Hispanic controls 2,071 Hispanic cases, 5,749 Hispanic controls, 1,519 Pima Indian ancestry cases, 1,680 Pima Indian ancestry controls, 427 Indigenous Mexican ancestry cases, 751 Indigenous Mexican ancestry controls. Illumina [158892] 1 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST006145 Exome genotyping array [Exome array] 8658 2018-08-23 29883787 Gregson CL 2018-06-05 Bone www.ncbi.nlm.nih.gov/pubmed/29883787 Genome-wide association study of extreme high bone mass: Contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes. Bone mineral density (total hip) 232 European ancestry high BMD individuals, 1,026 European ancestry moderate high BMD individuals, 852 European ancestry low BMD individuals NA Illumina [6379332] (imputed) 18 hip bone mineral density http://www.ebi.ac.uk/efo/EFO_0007702 GCST006143 Genome-wide genotyping array 2110 2018-08-23 29883787 Gregson CL 2018-06-05 Bone www.ncbi.nlm.nih.gov/pubmed/29883787 Genome-wide association study of extreme high bone mass: Contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes. High bone mineral density 232 European ancestry cases, 5,667 population controls NA NR [NR] 0 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST006141 Genome-wide genotyping array 5899 2018-08-23 29883787 Gregson CL 2018-06-05 Bone www.ncbi.nlm.nih.gov/pubmed/29883787 Genome-wide association study of extreme high bone mass: Contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes. Lumbar spine bone mineral density 232 European ancestry high BMD individuals, 613 European ancestry moderate high BMD individuals, 535 European ancestry low BMD individuals 30,970 individuals Illumina [6379332] (imputed) 0 spine bone mineral density http://www.ebi.ac.uk/efo/EFO_0007701 GCST006142 Genome-wide genotyping array 1380 2018-08-09 29847655 Fan BJ 2018-05-01 Invest Ophthalmol Vis Sci www.ncbi.nlm.nih.gov/pubmed/29847655 Family-Based Genome-Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus. Central corneal thickness 195 South Indian ancestry individuals from 15 families 1,520 Singaporean Indian individuals, 4,038 Mexican American individuals, 6,911 European ancestry individuals Illumina [1223314] 1 central corneal thickness http://www.ebi.ac.uk/efo/EFO_0005213 GCST006050 Genome-wide genotyping array 210 2018-08-09 29847655 Fan BJ 2018-05-01 Invest Ophthalmol Vis Sci www.ncbi.nlm.nih.gov/pubmed/29847655 Family-Based Genome-Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus. Central corneal thickness 195 South Indian ancestry individuals from 15 families 4,038 Mexican American individuals, 4,806 European ancestry individuals Illumina [1223314] 2 central corneal thickness http://www.ebi.ac.uk/efo/EFO_0005213 GCST006049 Genome-wide genotyping array 210 2018-09-20 29808027 Tedja MS 2018-05-28 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29808027 Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error. Spherical equivalent 41,073 European ancestry individuals, 2,610 Erasmus Rucphen (founder/genetic isolate) individuals, 509 Talana (founder/genetic isolate) individuals, 15,044 East Asian ancestry individuals, 2,275 Malay ancestry individuals, 2,110 Indian ancestry individuals, 2,506 Asian ancestry individuals NA Affymetrix, Illumina [~ 9300000] (imputed) 49 refractive error measurement http://www.ebi.ac.uk/efo/EFO_0007814 GCST006289 Genome-wide genotyping array 66127 2018-09-20 29808027 Tedja MS 2018-05-28 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29808027 Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error. Myopia (age of diagnosis) 104,293 European ancestry individuals NA Illumina [~ 10600000] (imputed) 112 age at onset, Myopia http://www.ebi.ac.uk/efo/EFO_0004847, http://purl.obolibrary.org/obo/HP_0000545 GCST006290 Genome-wide genotyping array 104293 2018-09-20 29808027 Tedja MS 2018-05-28 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29808027 Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error. Spherical equivalent or myopia (age of diagnosis) 145,366 European ancestry individuals, 2,610 Erasmus Rucphen (founder/genetic isolate) individuals, 509 Talana (founder/genetic isolate) individuals, 15,044 East Asian ancestry individuals, 2,275 Malay ancestry individuals, 2,110 Indian ancestry individuals, 2,506 Asian ancestry individuals NA Affymetrix, Illumina [~ 11000000] (imputed) 140 age at onset, Myopia, refractive error measurement http://www.ebi.ac.uk/efo/EFO_0004847, http://purl.obolibrary.org/obo/HP_0000545, http://www.ebi.ac.uk/efo/EFO_0007814 GCST006291 Genome-wide genotyping array 170420 2018-10-16 30003307 Fall T 2018-07-12 Diabetologia www.ncbi.nlm.nih.gov/pubmed/30003307 Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank. Coronary artery disease in diabetes 3,968 British ancestry cases, 11,698 British ancestry controls NA Affymetrix [9087334] (imputed) 2 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST006405 Genome-wide genotyping array 15666 2021-04-07 32888428 Krebs K 2020-08-26 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32888428 Genome-wide Study Identifies Association between HLA-B∗55:01 and Self-Reported Penicillin Allergy. Penicillin allergy 29,396 European ancestry cases, 452,094 European ancestry controls 87,996 European ancestry cases, 1,031,087 European ancestry controls Affymetrix [19724685] (imputed) 1 drug allergy http://www.ebi.ac.uk/efo/EFO_0009482 GCST011458 Genome-wide genotyping array 481490 2020-01-27 30979435 Lo MT 2019-03-12 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/30979435 Identification of genetic heterogeneity of Alzheimer's disease across age. Alzheimer's disease (onset at age over 80) 2,399 European ancestry cases, 4,160 European ancestry controls NA Affymetrix, Illumina [38043082] (imputed) 2 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST009497 Genome-wide genotyping array 6559 2020-01-27 30979435 Lo MT 2019-03-12 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/30979435 Identification of genetic heterogeneity of Alzheimer's disease across age. Alzheimer's disease (onset between ages 58 and 79) 7,316 European ancestry cases, 7,579 European ancestry controls NA Affymetrix, Illumina [38043082] (imputed) 28 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST009496 Genome-wide genotyping array 14895 2020-02-05 31372216 Haaland OA 2019-06-24 F1000Res www.ncbi.nlm.nih.gov/pubmed/31372216 A genome-wide scan of cleft lip triads identifies parent-of-origin interaction effects between ANK3 and maternal smoking, and between ARHGEF10 and alcohol consumption. Cleft lip with or without cleft palate x maternal periconceptional alcohol use interaction (parent of origin effect) 825 European ancestry case-parent duos or trios, 1,024 Asian ancestry case-parent duos or trios, 59 case-parent duos or trios NA NR [341191] 3 Cleft palate, cleft lip, alcohol exposure measurement, parental genotype effect measurement http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959, http://www.ebi.ac.uk/efo/EFO_0009113, http://www.ebi.ac.uk/efo/EFO_0005939 GCST009542 Genome-wide genotyping array 1908 2020-02-05 31372216 Haaland OA 2019-06-24 F1000Res www.ncbi.nlm.nih.gov/pubmed/31372216 A genome-wide scan of cleft lip triads identifies parent-of-origin interaction effects between ANK3 and maternal smoking, and between ARHGEF10 and alcohol consumption. Cleft lip with or without cleft palate x maternal periconceptional smoking interaction (parent of origin effect) 825 European ancestry case-parent duos or trios, 1,024 Asian ancestry case-parent duos or trios, 59 case-parent duos or trios NA NR [341191] 9 Cleft palate, tobacco smoke exposure measurement, cleft lip, parental genotype effect measurement http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0009115, http://www.ebi.ac.uk/efo/EFO_0003959, http://www.ebi.ac.uk/efo/EFO_0005939 GCST009544 Genome-wide genotyping array 1908 2020-02-05 31372216 Haaland OA 2019-06-24 F1000Res www.ncbi.nlm.nih.gov/pubmed/31372216 A genome-wide scan of cleft lip triads identifies parent-of-origin interaction effects between ANK3 and maternal smoking, and between ARHGEF10 and alcohol consumption. Cleft lip with or without cleft palate x maternal periconceptional vitamin use interaction (parent of origin effect) 825 European ancestry case-parent duos or trios, 1,024 Asian ancestry case-parent duos or trios, 59 case-parent duos or trios NA NR [341191] 8 vitamin supplement exposure measurement, Cleft palate, cleft lip, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0009116, http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959, http://www.ebi.ac.uk/efo/EFO_0005939 GCST009543 Genome-wide genotyping array 1908 2020-10-15 32005708 Forgetta V 2020-01-31 Diabetes www.ncbi.nlm.nih.gov/pubmed/32005708 Rare Genetic Variants of Large Effect Influence Risk of Type 1 Diabetes. Type 1 diabetes 9,266 European ancestry cases, 15,574 European ancestry controls 4,329 European ancestry cases, 9,543 European ancestry controls Affymetrix, Illumina [9061522] (imputed) 6 type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001359 GCST010681 Genome-wide genotyping array 24840 2020-05-28 32109663 Feitosa MF 2020-02-14 Atherosclerosis www.ncbi.nlm.nih.gov/pubmed/32109663 Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies. HDL cholesterol levels 3,567 European ancestry men, 4,171 European ancestry women NA Affymetrix, Illumina [6523511] (imputed) 12 HDL cholesterol change measurement http://www.ebi.ac.uk/efo/EFO_0007805 GCST009996 Genome-wide genotyping array 7738 2020-04-24 32108986 Price KM 2020-02-27 Genes Brain Behav www.ncbi.nlm.nih.gov/pubmed/32108986 Genome-Wide Association Study of Word Reading: Overlap with Risk Genes for Neurodevelopmental Disorders. Reading disability 4,494 European ancestry cases, 306 European ancestry siblings NA Illumina [5300000] (imputed) 7 dyslexia http://www.ebi.ac.uk/efo/EFO_0005424 GCST009897 Genome-wide genotyping array 4800 2020-03-23 31900758 Han X 2020-01-03 Eur J Epidemiol www.ncbi.nlm.nih.gov/pubmed/31900758 Using Mendelian randomization to evaluate the causal relationship between serum C-reactive protein levels and age-related macular degeneration. C-reactive protein levels 418,642 British ancestry individuals NA NR [NR] 526 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST009777 Genome-wide genotyping array 418642 2020-03-23 31900758 Han X 2020-01-03 Eur J Epidemiol www.ncbi.nlm.nih.gov/pubmed/31900758 Using Mendelian randomization to evaluate the causal relationship between serum C-reactive protein levels and age-related macular degeneration. Advanced age-related macular degeneration 12,711 European ancestry cases, 14,590 European ancestry controls NA NR [NR] (imputed) 0 age-related macular degeneration http://www.ebi.ac.uk/efo/EFO_0001365 GCST009776 Genome-wide genotyping array 27301 2018-06-05 29246731 de Toro-Martin J 2017-11-02 J Clin Lipidol www.ncbi.nlm.nih.gov/pubmed/29246731 A common variant in ARHGEF10 alters delta-6 desaturase activity and influence susceptibility to hypertriglyceridemia. Delta-5 desaturase activity response to n3-polyunsaturated fat supplement 81 extreme responder individuals, 60 non-responder individuals NA Illumina [2668805] 6 delta-5 desaturase measurement, response to polyunsaturated fatty acid supplementation http://www.ebi.ac.uk/efo/EFO_0007764, http://www.ebi.ac.uk/efo/EFO_0009131 GCST005668 Genome-wide genotyping array 141 2018-06-05 29246731 de Toro-Martin J 2017-11-02 J Clin Lipidol www.ncbi.nlm.nih.gov/pubmed/29246731 A common variant in ARHGEF10 alters delta-6 desaturase activity and influence susceptibility to hypertriglyceridemia. Delta-6 desaturase activity response to n3-polyunsaturated fat supplement 81 extreme responder individuals, 60 non-responder individuals NA Illumina [2668805] 1 delta-6 desaturase measurement, response to polyunsaturated fatty acid supplementation http://www.ebi.ac.uk/efo/EFO_0007765, http://www.ebi.ac.uk/efo/EFO_0009131 GCST005669 Genome-wide genotyping array 141 2018-08-10 24847101 Rudkowska I 2014-05-19 J Lipid Res www.ncbi.nlm.nih.gov/pubmed/24847101 Genome-wide association study of the plasma triglyceride response to an n-3 polyunsaturated fatty acid supplementation. Response to long-chain n-3 polyunsaturated fatty acid supplementation (change in triglyceride levels) 81 responder individuals, 60 non-responder individuals NA Illumina [2668805] 5 triglyceride change measurement, response to long-chain n-3 PUFA dietary supplementation http://www.ebi.ac.uk/efo/EFO_0007681, http://www.ebi.ac.uk/efo/EFO_0009308 GCST006055 Genome-wide genotyping array 141 2018-08-13 29891935 Choquet H 2018-06-11 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29891935 A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci. Glaucoma (primary open-angle) 3,836 European ancestry cases, 48,065 European ancestry controls, 411 Hispanic cases, 4,778 Hispanic controls, 441 East Asian ancestry cases, 4,034 East Asian ancestry controls, 298 African American cases, 1,549 African American controls 6,687 European ancestry cases, 155,514 European ancestry controls, 204 South Asian ancestry cases, 4,916 South Asian ancestry controls, 272 African British cases, 4,831 African British controls, 22 East Asian ancestry cases, 873 East Asian ancestry controls, 144 mixed ancestry cases, 3,427 mixed ancestry controls Affymetrix [at least 665500] (imputed) 9 open-angle glaucoma http://www.ebi.ac.uk/efo/EFO_0004190 GCST006066 Genome-wide genotyping array 63412 2018-08-13 29891935 Choquet H 2018-06-11 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29891935 A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci. Glaucoma (primary open-angle) 6,687 European ancestry cases, 155,514 European ancestry controls, 204 South Asian ancestry cases, 4,916 South Asian ancestry controls, 272 African British cases, 4,831 African British controls, 22 East Asian ancestry cases, 873 East Asian ancestry controls, 144 mixed ancestry cases, 3,427 mixed ancestry controls 3,836 European ancestry cases, 48,065 European ancestry controls, 411 Hispanic cases, 4,778 Hispanic controls, 441 East Asian ancestry cases, 4,034 East Asian ancestry controls, 298 African American cases, 1,549 African American controls NR [NR] (imputed) 9 open-angle glaucoma http://www.ebi.ac.uk/efo/EFO_0004190 GCST006067 Genome-wide genotyping array 176890 2018-08-13 29891935 Choquet H 2018-06-11 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29891935 A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci. Glaucoma (primary open-angle) 10,523 European ancestry cases, 203,579 European ancestry controls, 411 Hispanic cases, 4,778 Hispanic controls, 463 East Asian ancestry cases, 4,907 East Asian ancestry controls, 298 African American cases, 1,549 African American controls, 204 South Asian ancestry cases, 4,916 South Asian ancestry controls, 272 African British cases, 4,831 African British controls, 144 mixed ancestry cases, 3,427 mixed ancestry controls NA Affymetrix [at least 665500] (imputed) 47 open-angle glaucoma http://www.ebi.ac.uk/efo/EFO_0004190 GCST006065 Genome-wide genotyping array 240302 2018-10-04 30003630 Minica CC 2018-07-13 Addiction www.ncbi.nlm.nih.gov/pubmed/30003630 GENOME-WIDE ASSOCIATION META-ANALYSIS OF AGE AT FIRST CANNABIS USE. Cannabis use (age at onset) 24,953 European ancestry individuals 3,735 European ancestry individuals Affymetrix, Illumina, Perlegen [6163759] (imputed) 3 Cannabis use, age at onset http://www.ebi.ac.uk/efo/EFO_0007585, http://www.ebi.ac.uk/efo/EFO_0004847 GCST006386 Genome-wide genotyping array 24953 2018-10-05 29988085 Merino J 2018-07-09 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/29988085 Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. Dietary macronutrient intake 91,114 European ancestry individuals 177,315 European ancestry individuals Affymetrix, Illumina [1180000] (imputed) 5 energy intake http://www.ebi.ac.uk/efo/EFO_0003939 GCST006388 Genome-wide genotyping array 91114 2018-09-25 29975729 Kim TH 2018-07-05 PLoS One www.ncbi.nlm.nih.gov/pubmed/29975729 Identification of novel susceptibility loci associated with hepatitis B surface antigen seroclearance in chronic hepatitis B. Hepatitis B surface antigen seroclearance in chronic hepatitis B infection 100 Korean ancestry cases, 100 Korean ancestry controls NA Illumina [1365088] 4 Hepatitis B virus surface antigen seropositivity http://www.ebi.ac.uk/efo/EFO_0009345 GCST006364 Genome-wide genotyping array 200 2018-09-19 29973135 Rimpela JM 2018-07-04 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/29973135 Genome-wide association study of nocturnal blood pressure dipping in hypertensive patients. Systolic blood pressure night-to-day ratio in hypertension 204 Finnish ancestry individuals NA Illumina [631844] 2 systolic blood pressure change measurement http://www.ebi.ac.uk/efo/EFO_0006944 GCST006274 Genome-wide genotyping array 204 2018-09-19 29973135 Rimpela JM 2018-07-04 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/29973135 Genome-wide association study of nocturnal blood pressure dipping in hypertensive patients. Diastolic blood pressure night-to-day ratio in hypertension 204 Finnish ancestry individuals NA Illumina [631844] 5 diastolic blood pressure change measurement http://www.ebi.ac.uk/efo/EFO_0006945 GCST006273 Genome-wide genotyping array 204 2018-09-13 30004843 Ge S 2018-07-01 OMICS www.ncbi.nlm.nih.gov/pubmed/30004843 Type 2 Diabetes Mellitus: Integrative Analysis of Multiomics Data for Biomarker Discovery. Elevated fasting plasma glucose 76 Chinese ancestry cases, 435 Chinese ancestry controls NA Illumina [69485] 5 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST006257 Genome-wide genotyping array 511 2021-04-28 32890573 Yan Q 2020-09-02 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/32890573 A genome-wide association study of asthma hospitalizations in adults. Exacerbations requiring hospitalisation in asthma 1,658 British ancestry cases, 32,509 British ancestry controls NA Affymetrix [87696888] (imputed) 36 asthma exacerbation measurement http://www.ebi.ac.uk/efo/EFO_0007614 GCST011570 Genome-wide genotyping array 34167 2021-07-09 32865774 Sima C 2020-08-31 Int Urol Nephrol www.ncbi.nlm.nih.gov/pubmed/32865774 Genome-wide association study of nephrolithiasis in an Eastern European population. Nephrolithiasis 329 Romanian ancestry cases, 5,105 Romanian ancestry controls NA Illumina [104390] 0 nephrolithiasis http://www.ebi.ac.uk/efo/EFO_0004253 GCST012019 Genome-wide genotyping array 5434 2020-02-19 31993563 Ware EB 2019-11-22 Mayo Clin Proc Innov Qual Outcomes www.ncbi.nlm.nih.gov/pubmed/31993563 Genome-wide Association Study of 24-Hour Urinary Excretion of Calcium, Magnesium, and Uric Acid. Urinary calcium excretion 6,462 European ancestry individuals NA NR [NR] (imputed) 15 calcium measurement http://www.ebi.ac.uk/efo/EFO_0004838 GCST009676 Genome-wide genotyping array 6462 2020-02-19 31993563 Ware EB 2019-11-22 Mayo Clin Proc Innov Qual Outcomes www.ncbi.nlm.nih.gov/pubmed/31993563 Genome-wide Association Study of 24-Hour Urinary Excretion of Calcium, Magnesium, and Uric Acid. Urinary magnesium excretion 6,462 European ancestry individuals NA NR [NR] (imputed) 9 magnesium measurement http://www.ebi.ac.uk/efo/EFO_0004845 GCST009675 Genome-wide genotyping array 6462 2020-02-19 31993563 Ware EB 2019-11-22 Mayo Clin Proc Innov Qual Outcomes www.ncbi.nlm.nih.gov/pubmed/31993563 Genome-wide Association Study of 24-Hour Urinary Excretion of Calcium, Magnesium, and Uric Acid. Urinary uric acid excretion 6,462 European ancestry individuals NA NR [NR] (imputed) 3 uric acid measurement http://www.ebi.ac.uk/efo/EFO_0004761 GCST009674 Genome-wide genotyping array 6462 2020-07-06 31993563 Ware EB 2019-11-22 Mayo Clin Proc Innov Qual Outcomes www.ncbi.nlm.nih.gov/pubmed/31993563 Genome-wide Association Study of 24-Hour Urinary Excretion of Calcium, Magnesium, and Uric Acid. Urinary volume 6,462 European ancestry individuals NA NR [NR] (imputed) 3 urine volume measurement http://www.ebi.ac.uk/efo/EFO_0010604 GCST010120 Genome-wide genotyping array 6462 2020-04-17 32109421 Li C 2020-02-20 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32109421 Genome-Wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. Leukocyte telomere length 78,592 European ancestry individuals NA Affymetrix, Illumina, Perlegen [up to 30071938] (imputed) 49 telomere length http://www.ebi.ac.uk/efo/EFO_0004505 GCST009856 Genome-wide genotyping array 78592 2020-04-17 30402224 Yamada Y 2018-09-17 Biomed Rep www.ncbi.nlm.nih.gov/pubmed/30402224 Identification of 26 novel loci that confer susceptibility to early-onset coronary artery disease in a Japanese population. Coronary artery disease 1,482 Japanese ancestry cases, 5,774 Japanese ancestry controls NA Illumina [up to 244000] 10 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST009879 Exome genotyping array [Exome array] 7256 2020-07-20 28031487 Guo MH 2016-12-28 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/28031487 Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms. Basophil count 5,578 European ancestry individuals NA NR [16536512] (imputed) 2 basophil count http://www.ebi.ac.uk/efo/EFO_0005090 GCST010240 Genome-wide genotyping array, Genome-wide sequencing 5578 2020-07-20 28031487 Guo MH 2016-12-28 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/28031487 Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms. Eosinophil counts 5,586 European ancestry individuals NA NR [16536512] (imputed) 0 eosinophil count http://www.ebi.ac.uk/efo/EFO_0004842 GCST010239 Genome-wide genotyping array, Genome-wide sequencing 5586 2020-07-20 28031487 Guo MH 2016-12-28 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/28031487 Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms. Hemoglobin 4,221 European ancestry individuals NA NR [16536512] (imputed) 0 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST010238 Genome-wide genotyping array, Genome-wide sequencing 4221 2020-07-20 28031487 Guo MH 2016-12-28 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/28031487 Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms. Hematocrit 2,096 European ancestry individuals NA NR [16536512] (imputed) 0 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST010237 Genome-wide genotyping array, Genome-wide sequencing 2096 2020-07-20 28031487 Guo MH 2016-12-28 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/28031487 Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms. Lymphocyte counts 5,614 European ancestry individuals NA NR [16536512] (imputed) 0 lymphocyte count http://www.ebi.ac.uk/efo/EFO_0004587 GCST010236 Genome-wide genotyping array, Genome-wide sequencing 5614 2020-07-20 28031487 Guo MH 2016-12-28 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/28031487 Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms. Mean corpuscular hemoglobin 6,883 European ancestry individuals NA NR [16536512] (imputed) 2 mean corpuscular hemoglobin http://www.ebi.ac.uk/efo/EFO_0004527 GCST010235 Genome-wide genotyping array, Genome-wide sequencing 6883 2020-07-20 28031487 Guo MH 2016-12-28 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/28031487 Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms. Mean corpuscular hemoglobin concentration 6,891 European ancestry individuals NA NR [16536512] (imputed) 0 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST010234 Genome-wide genotyping array, Genome-wide sequencing 6891 2020-07-20 28031487 Guo MH 2016-12-28 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/28031487 Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms. Mean corpuscular volume 6,891 European ancestry individuals NA NR [16536512] (imputed) 1 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST010233 Genome-wide genotyping array, Genome-wide sequencing 6891 2020-07-20 28031487 Guo MH 2016-12-28 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/28031487 Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms. Monocyte count 5,533 European ancestry individuals NA NR [16536512] (imputed) 1 monocyte count http://www.ebi.ac.uk/efo/EFO_0005091 GCST010232 Genome-wide genotyping array, Genome-wide sequencing 5533 2020-07-20 28031487 Guo MH 2016-12-28 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/28031487 Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms. Mean platelet volume 6,228 European ancestry individuals NA NR [16536512] (imputed) 6 mean platelet volume http://www.ebi.ac.uk/efo/EFO_0004584 GCST010231 Genome-wide genotyping array, Genome-wide sequencing 6228 2020-07-20 28031487 Guo MH 2016-12-28 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/28031487 Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms. Neutrophil count 2,080 European ancestry individuals NA NR [16536512] (imputed) 0 neutrophil count http://www.ebi.ac.uk/efo/EFO_0004833 GCST010230 Genome-wide genotyping array, Genome-wide sequencing 2080 2020-07-20 28031487 Guo MH 2016-12-28 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/28031487 Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms. Platelet count 2,083 European ancestry individuals NA NR [16536512] (imputed) 4 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST010229 Genome-wide genotyping array, Genome-wide sequencing 2083 2020-07-20 28031487 Guo MH 2016-12-28 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/28031487 Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms. Red blood cell count 7,113 European ancestry individuals NA NR [16536512] (imputed) 1 erythrocyte count http://www.ebi.ac.uk/efo/EFO_0004305 GCST010228 Genome-wide genotyping array, Genome-wide sequencing 7113 2020-07-20 28031487 Guo MH 2016-12-28 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/28031487 Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms. White blood cell count 7,116 European ancestry individuals NA NR [16536512] (imputed) 0 leukocyte count http://www.ebi.ac.uk/efo/EFO_0004308 GCST010227 Genome-wide genotyping array, Genome-wide sequencing 7116 2018-07-04 29771307 Aponte JL 2018-05-16 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/29771307 Assessment of rosacea symptom severity by genome-wide association study and expression analysis highlights immuno-inflammatory and skin pigmentation genes. Rosacea symptom severity 73,265 European ancestry individuals NA Illumina [at least 950000] (imputed) 98 rosacea severity measurement http://www.ebi.ac.uk/efo/EFO_0009180 GCST005790 Genome-wide genotyping array 73265 2020-01-09 31798171 Bonnemaijer PWM 2019-11-27 Commun Biol www.ncbi.nlm.nih.gov/pubmed/31798171 Multi-trait genome-wide association study identifies new loci associated with optic disc parameters. Optic cup area 24,493 European ancestry individuals NA Affymetrix, Illumina [11830838] (imputed) 24 optic cup area measurement http://www.ebi.ac.uk/efo/EFO_0006940 GCST009404 Genome-wide genotyping array 24493 2020-01-09 31798171 Bonnemaijer PWM 2019-11-27 Commun Biol www.ncbi.nlm.nih.gov/pubmed/31798171 Multi-trait genome-wide association study identifies new loci associated with optic disc parameters. Optic disc area 24,509 European ancestry individuals NA Affymetrix, Illumina [11764957] (imputed) 18 optic disc area measurement http://www.ebi.ac.uk/efo/EFO_0006937 GCST009411 Genome-wide genotyping array 24509 2020-01-09 31798171 Bonnemaijer PWM 2019-11-27 Commun Biol www.ncbi.nlm.nih.gov/pubmed/31798171 Multi-trait genome-wide association study identifies new loci associated with optic disc parameters. Vertical cup-disc ratio 25,180 European ancestry individuals NA Affymetrix, Illumina [11901698] (imputed) 24 cup-to-disc ratio measurement http://www.ebi.ac.uk/efo/EFO_0006939 GCST009412 Genome-wide genotyping array 25180 2020-01-09 31798171 Bonnemaijer PWM 2019-11-27 Commun Biol www.ncbi.nlm.nih.gov/pubmed/31798171 Multi-trait genome-wide association study identifies new loci associated with optic disc parameters. Intraocular pressure 31,269 European ancestry individuals NA Affymetrix, Illumina [12426120] (imputed) 16 intraocular pressure measurement http://www.ebi.ac.uk/efo/EFO_0004695 GCST009413 Genome-wide genotyping array 31269 2020-01-09 31798171 Bonnemaijer PWM 2019-11-27 Commun Biol www.ncbi.nlm.nih.gov/pubmed/31798171 Multi-trait genome-wide association study identifies new loci associated with optic disc parameters. Central corneal thickness 16,204 European ancestry individuals NA Affymetrix, Illumina [9249813] (imputed) 34 central corneal thickness http://www.ebi.ac.uk/efo/EFO_0005213 GCST009414 Genome-wide genotyping array 16204 2020-01-09 31798171 Bonnemaijer PWM 2019-11-27 Commun Biol www.ncbi.nlm.nih.gov/pubmed/31798171 Multi-trait genome-wide association study identifies new loci associated with optic disc parameters. Optic nerve head parameters (multi-trait analysis) up to 25,180 European ancestry individuals up to 7,792 Chinese ancestry individuals, 3,280 Malay ancestry individuals, 3,400 Indian ancestry individuals Affymetrix, Illumina [up to 11901698] (imputed) 7 cup-to-disc ratio measurement, optic cup area measurement, optic disc area measurement http://www.ebi.ac.uk/efo/EFO_0006939, http://www.ebi.ac.uk/efo/EFO_0006940, http://www.ebi.ac.uk/efo/EFO_0006937 GCST009416 Genome-wide genotyping array 25180 2020-01-09 31798171 Bonnemaijer PWM 2019-11-27 Commun Biol www.ncbi.nlm.nih.gov/pubmed/31798171 Multi-trait genome-wide association study identifies new loci associated with optic disc parameters. Intraocular pressure and central corneal thickness (multi-trait analysis) up to 31,269 European ancestry individuals up to 7,792 Chinese ancestry individuals, 3,280 Malay ancestry individuals, 3,400 Indian ancestry individuals Affymetrix, Illumina [up to 12426120] (imputed) 8 central corneal thickness, intraocular pressure measurement http://www.ebi.ac.uk/efo/EFO_0005213, http://www.ebi.ac.uk/efo/EFO_0004695 GCST009415 Genome-wide genotyping array 31269 2018-07-25 29769526 Estrada K 2018-05-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29769526 A whole-genome sequence study identifies genetic risk factors for neuromyelitis optica. Neuromyelitis optica 66 European ancestry AQP4-IgG antibody seropositive cases, 63 European ancestry AQP4-IgG antibody seronegative cases, 784 European ancestry controls 66 European ancestry AQP4-IgG antibody seropositive cases, 20 European ancestry AQP4-IgG antibody seronegative cases, 460 European ancestry controls Affymetrix [6804788] (imputed) 7 neuromyelitis optica http://www.ebi.ac.uk/efo/EFO_0004256 GCST005964 Genome-wide genotyping array 921 2019-01-22 29769526 Estrada K 2018-05-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29769526 A whole-genome sequence study identifies genetic risk factors for neuromyelitis optica. Neuromyelitis optica (AQP4-IgG-positive) 66 European ancestry cases, 784 European ancestry controls 66 European ancestry cases, 460 European ancestry controls Affymetrix [6804788] (imputed) 7 AQP4-IgG-positive neuromyelitis optica http://www.ebi.ac.uk/efo/EFO_0009584 GCST006937 Genome-wide genotyping array 850 2019-01-22 29769526 Estrada K 2018-05-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29769526 A whole-genome sequence study identifies genetic risk factors for neuromyelitis optica. Neuromyelitis optica (AQP4-IgG-negative) 63 European ancestry cases, 784 European ancestry controls 20 European ancestry cases, 460 European ancestry controls Affymetrix [6804788] (imputed) 0 AQP4-IgG-negative neuromyelitis optica http://www.ebi.ac.uk/efo/EFO_0009585 GCST006938 Genome-wide genotyping array 847 2020-04-20 31794020 Matana A 2019-12-03 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/31794020 Genome-wide analysis identifies two susceptibility loci for positive thyroid peroxidase and thyroglobulin antibodies. Thyroid autoantibody positivity (anti-thyroglobulin (TgAb) and/or anti-thyroid peroxidase (TPOAb) levels) 619 Croatian ancestry cases, 1,994 Croatian ancestry controls NA Illumina [7411206] (imputed) 4 thyroid peroxidase antibody measurement, anti-thyroglobulin antibody measurement http://www.ebi.ac.uk/efo/EFO_0005666, http://www.ebi.ac.uk/efo/EFO_0009896 GCST009888 Genome-wide genotyping array 2613 2018-11-15 26177304 Waterman M 2015-09-01 Inflamm Bowel Dis www.ncbi.nlm.nih.gov/pubmed/26177304 Predictors of Outcome in Ulcerative Colitis. Ulcerative colitis 507 European ancestry cases, 61 Asian ancestry cases, 7 American ancestry cases, 2 Hispanic ancestry cases, 24 cases NA Illumina [ImmunoChip] 0 ulcerative colitis http://www.ebi.ac.uk/efo/EFO_0000729 GCST006583 Targeted genotyping array [ImmunoChip] 601 2018-07-16 29739929 Visconti A 2018-05-08 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29739929 Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure. Low tan response 46,768 European ancestry low tanning cases, 74,528 European ancestry moderate and high tanning controls 15,547 European ancestry low tanning cases, 39,835 European moderate and high tanning ancestry controls Affymetrix [8351141] (imputed) 79 suntan http://www.ebi.ac.uk/efo/EFO_0004279 GCST005897 Genome-wide genotyping array 121296 2018-07-16 29739929 Visconti A 2018-05-08 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29739929 Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure. Non-melanoma skin cancer 5,912 European ancestry cases, 181,740 European ancestry controls NA Affymetrix [5734850] (imputed) 82 non-melanoma skin carcinoma http://www.ebi.ac.uk/efo/EFO_0009260 GCST005896 Genome-wide genotyping array 187652 2020-06-16 31791832 Koks S 2019-11-12 J Arthroplasty www.ncbi.nlm.nih.gov/pubmed/31791832 The Genetic Variations Associated With Time to Aseptic Loosening After Total Joint Arthroplasty. Time to aseptic loosening in total joint arthroplasty 97 individuals NA Illumina [up to 600000] 4 aseptic loosening http://www.ebi.ac.uk/efo/EFO_0010725 GCST010082 Genome-wide genotyping array 97 2020-06-16 31791832 Koks S 2019-11-12 J Arthroplasty www.ncbi.nlm.nih.gov/pubmed/31791832 The Genetic Variations Associated With Time to Aseptic Loosening After Total Joint Arthroplasty. Aseptic loosening in total joint arthroplasty 97 cases, 289 controls NA Illumina [up to 600000] 6 aseptic loosening http://www.ebi.ac.uk/efo/EFO_0010725 GCST010081 Genome-wide genotyping array 386 2018-07-11 28658209 Huang H 2017-06-28 Nature www.ncbi.nlm.nih.gov/pubmed/28658209 Fine-mapping inflammatory bowel disease loci to single-variant resolution. Inflammatory bowel disease up to 20,155 European ancestry Crohn's disease cases, up to 15,191 European ancestry ulcerative colitis cases, up to 34,257 European ancestry controls NA Illumina [161681] (imputed) 0 ulcerative colitis, Crohn's disease, inflammatory bowel disease http://www.ebi.ac.uk/efo/EFO_0000729, http://www.ebi.ac.uk/efo/EFO_0000384, http://www.ebi.ac.uk/efo/EFO_0003767 GCST005837 Targeted genotyping array [ImmunoChip] 69603 2018-12-19 29885931 Langefeld CD 2018-06-06 Kidney Int www.ncbi.nlm.nih.gov/pubmed/29885931 Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions. End stage renal disease x APOL1 genotype interaction 1,749 African American ESRD cases, 901 African American lupus nephritis-ESRD cases NA Illumina [NR] 3 chronic kidney disease, APOL1 risk genotype carrier status http://www.ebi.ac.uk/efo/EFO_0003884, http://www.ebi.ac.uk/efo/EFO_0009324 GCST006813 Genome-wide genotyping array 2650 2018-12-19 29885931 Langefeld CD 2018-06-06 Kidney Int www.ncbi.nlm.nih.gov/pubmed/29885931 Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions. End stage renal disease in APOL1 risk genotype-negative individuals 945 African American ESRD cases, 988 African American controls, 678 African American lupus nephritis-ESRD cases, 465 African American systemic lupus erythrematosus without nephropathy controls NA Illumina [NR] 2 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST006815 Genome-wide genotyping array 3076 2018-12-19 29885931 Langefeld CD 2018-06-06 Kidney Int www.ncbi.nlm.nih.gov/pubmed/29885931 Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions. End stage renal disease in APOL1 risk genotype-positive individuals 803 African American ESRD cases, 148 African American controls, 223 African American lupus nephritis-ESRD cases, 55 African American systemic lupus erythrematosus without nephropathy controls NA Illumina [NR] 0 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST006816 Genome-wide genotyping array 1229 2018-12-19 29885931 Langefeld CD 2018-06-06 Kidney Int www.ncbi.nlm.nih.gov/pubmed/29885931 Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions. End-stage renal disease 1,749 African American ESRD cases, 1,136 African American controls, 901 African American lupus nephritis-ESRD cases, 520 African American systemic lupus erythrematosus without nephropathy controls NA Illumina [NR] 7 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST006814 Genome-wide genotyping array 4306 2018-09-05 29310926 Sharma A 2018-01-05 J Autoimmun www.ncbi.nlm.nih.gov/pubmed/29310926 Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort. Type 1 diabetes in high risk HLA genotype individuals (time to event) 5,806 European ancestry children NA Illumina [131847] 5 disease free survival, type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0000409, http://www.ebi.ac.uk/efo/EFO_0001359 GCST006196 Targeted genotyping array [ImmunoChip] 5806 2018-09-05 29310926 Sharma A 2018-01-05 J Autoimmun www.ncbi.nlm.nih.gov/pubmed/29310926 Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort. Type 1 diabetes autoantibodies in high risk HLA genotype individuals (time to event) 5,806 European ancestry children NA Illumina [131847] 9 event free survival time, type I diabetes mellitus, autoantibody measurement http://www.ebi.ac.uk/efo/EFO_0000482, http://www.ebi.ac.uk/efo/EFO_0001359, http://www.ebi.ac.uk/efo/EFO_0004866 GCST006197 Targeted genotyping array [ImmunoChip] 5806 2018-12-19 30271922 Clifton EAD 2018-05-03 Commun Biol www.ncbi.nlm.nih.gov/pubmed/30271922 Genome-wide association study for risk taking propensity indicates shared pathways with body mass index. Self-reported risk-taking behaviour 113,882 European ancestry cases, 322,354 European ancestry controls NA Affymetrix [7736308] (imputed) 26 risk-taking behaviour http://www.ebi.ac.uk/efo/EFO_0008579 GCST006810 Genome-wide genotyping array 436236 2018-12-19 30271922 Clifton EAD 2018-05-03 Commun Biol www.ncbi.nlm.nih.gov/pubmed/30271922 Genome-wide association study for risk taking propensity indicates shared pathways with body mass index. Body mass index 772,825 individuals NA Affymetrix [NR] 4 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST006811 Genome-wide genotyping array 772825 2018-12-19 30271922 Clifton EAD 2018-05-03 Commun Biol www.ncbi.nlm.nih.gov/pubmed/30271922 Genome-wide association study for risk taking propensity indicates shared pathways with body mass index. Smoking status (ever vs never smokers) 207,229 European ancestry ever smoker cases, 243,177 European ancestry never smoker controls NA Affymetrix [7736308] (imputed) 7 smoking status measurement http://www.ebi.ac.uk/efo/EFO_0006527 GCST006812 Genome-wide genotyping array 450406 2018-08-22 29953918 Deng C 2018-06-25 Gene www.ncbi.nlm.nih.gov/pubmed/29953918 Identification of three novel loci of ALDH2 Gene for Serum Folate levels in a Male Chinese Population by Genome-Wide Association Study. Serum folate levels 1,999 Han Chinese ancestry individuals NA Illumina [1940243] (imputed) 17 folic acid measurement http://www.ebi.ac.uk/efo/EFO_0005111 GCST006137 Genome-wide genotyping array 1999 2020-04-17 32002517 Julienne H 2020-01-24 NAR Genom Bioinform www.ncbi.nlm.nih.gov/pubmed/32002517 JASS: command line and web interface for the joint analysis of GWAS results. Insulin-related traits (multivariate analysis) 62,205 individuals NA NR [3144808] (imputed) 27 insulin measurement http://www.ebi.ac.uk/efo/EFO_0004467 GCST009863 Genome-wide genotyping array 62205 2020-05-28 32009195 Condreay LD 2020-02-03 Rheumatol Int www.ncbi.nlm.nih.gov/pubmed/32009195 Pharmacogenetic investigation of efficacy response to mepolizumab in eosinophilic granulomatosis with polyangiitis. Frequency of relapse in mepolizumab-treated eosinophilic granulomatosis with polyangiitis 61 individuals NA Affymetrix [7154205] (imputed) 2 response to mepolizumab, disease progression measurement http://www.ebi.ac.uk/efo/EFO_0008459, http://www.ebi.ac.uk/efo/EFO_0008336 GCST009999 Genome-wide genotyping array 61 2020-05-28 32009195 Condreay LD 2020-02-03 Rheumatol Int www.ncbi.nlm.nih.gov/pubmed/32009195 Pharmacogenetic investigation of efficacy response to mepolizumab in eosinophilic granulomatosis with polyangiitis. Average oral glucocorticoid dose in mepolizumab-treated eosinophilic granulomatosis with polyangiitis 61 individuals NA Affymetrix [7154205] (imputed) 12 response to mepolizumab, Glucocorticoid use measurement http://www.ebi.ac.uk/efo/EFO_0008459, http://www.ebi.ac.uk/efo/EFO_0009942 GCST009998 Genome-wide genotyping array 61 2020-05-28 32009195 Condreay LD 2020-02-03 Rheumatol Int www.ncbi.nlm.nih.gov/pubmed/32009195 Pharmacogenetic investigation of efficacy response to mepolizumab in eosinophilic granulomatosis with polyangiitis. Accrued duration of remission in mepolizumab-treated eosinophilic granulomatosis with polyangiitis 61 individuals NA Affymetrix [7154205] (imputed) 14 disease free survival, response to mepolizumab http://www.ebi.ac.uk/efo/EFO_0000409, http://www.ebi.ac.uk/efo/EFO_0008459 GCST010000 Genome-wide genotyping array 61 2020-04-20 24326010 Xavier JM 2013-12-10 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/24326010 FUT2: filling the gap between genes and environment in Behçet's disease? Behcet's disease 292 Iranian ancestry cases, 294 Iranian ancestry controls 684 Iranian ancestry cases, 532 Iranian ancestry controls, 1,215 Turkish ancestry cases, 1,278 Turkish ancestry controls Affymetrix [868254] 2 Behcet's syndrome http://www.ebi.ac.uk/efo/EFO_0003780 GCST009887 Genome-wide genotyping array 586 2020-06-02 32186652 Chen HY 2020-03-18 JAMA Cardiol www.ncbi.nlm.nih.gov/pubmed/32186652 Association of FADS1/2 Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis. Aortic valve stenosis 3,469 European ancestry cases, 41,234 European ancestry controls 3,751 European ancestry cases, 236,142 European ancestry controls, 2,175 cases, 25,347 controls Affymetrix [615643] 1 aortic stenosis http://www.ebi.ac.uk/efo/EFO_0000266 GCST010038 Genome-wide genotyping array 44703 2020-06-03 32193455 Ran S 2020-03-19 Sci Rep www.ncbi.nlm.nih.gov/pubmed/32193455 Replication of FTO Gene associated with lean mass in a Meta-Analysis of Genome-Wide Association Studies. Lean mass index 2,207 European ancestry individuals 44,296 European ancestry individuals Affymetrix [at least 746709] (imputed) 1 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST010040 Genome-wide genotyping array 2207 2021-06-03 32912934 Li M 2020-09-10 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/32912934 Genome-Wide Meta-Analysis Identifies Three Novel Susceptibility Loci and Reveals Ethnic Heterogeneity of Genetic Susceptibility for IgA Nephropathy. IgA nephropathy 2,628 Chinese ancestry cases, 11,563 Chinese ancestry controls 6,879 Han Chinese ancestry cases, 9,019 Han Chinese ancestry controls, 1,039 Italian ancestry cases, 1,289 Italian ancestry controls NR [3611808] (imputed) 12 IGA glomerulonephritis http://www.ebi.ac.uk/efo/EFO_0004194 GCST011781 Genome-wide genotyping array 14191 2019-03-13 30693016 Lin WY 2019-01-14 Front Genet www.ncbi.nlm.nih.gov/pubmed/30693016 Genome-Wide Gene-Environment Interaction Analysis Using Set-Based Association Tests. Diastolic blood pressure x alcohol consumption interaction (1df test) 1,764 Han Chinese and unknown ancestry alcohol drinkers, 14,779 Han Chinese and unknown ancestry non-drinkers NA NR [603741] 1 diastolic blood pressure, alcohol drinking http://www.ebi.ac.uk/efo/EFO_0006336, http://www.ebi.ac.uk/efo/EFO_0004329 GCST007287 Genome-wide genotyping array 16543 2019-03-13 30693016 Lin WY 2019-01-14 Front Genet www.ncbi.nlm.nih.gov/pubmed/30693016 Genome-Wide Gene-Environment Interaction Analysis Using Set-Based Association Tests. Systolic blood pressure x alcohol consumption interaction (1df test) 1,764 Han Chinese and unknown ancestry alcohol drinkers, 14,779 Han Chinese and unknown ancestry non-drinkers NA NR [603741] 0 systolic blood pressure, alcohol drinking http://www.ebi.ac.uk/efo/EFO_0006335, http://www.ebi.ac.uk/efo/EFO_0004329 GCST007288 Genome-wide genotyping array 16543 2019-06-21 30685440 Silbernagel G 2018-12-28 Atherosclerosis www.ncbi.nlm.nih.gov/pubmed/30685440 LDL triglycerides, hepatic lipase activity, and coronary artery disease: An epidemiologic and Mendelian randomization study. Low density lipoprotein triglyceride levels 2,900 German ancestry individuals NA Affymetrix [2543887] (imputed) 0 low density lipoprotein triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0009946 GCST007955 Genome-wide genotyping array 2900 2019-06-21 30674050 Spiegel AM 2019-01-23 Am J Perinatol www.ncbi.nlm.nih.gov/pubmed/30674050 A Genome-Wide Analysis of Clinical Chorioamnionitis among Preterm Infants. Maternal chorioamnionitis 213 preterm birth infant cases, 707 preterm birth infant controls NA Illumina [2384515] 0 chorioamnionitis http://www.ebi.ac.uk/efo/EFO_0009948 GCST007956 Genome-wide genotyping array 920 2021-04-16 32895509 Suzuki T 2020-09-07 Eur J Clin Nutr www.ncbi.nlm.nih.gov/pubmed/32895509 A genome-wide association study on fish consumption in a Japanese population-the Japan Multi-Institutional Collaborative Cohort study. Fish consumption 13,739 Japanese ancestry individuals 2,845 Japanese ancestry individuals Illumina [8504983] (imputed) 2 fish consumption measurement http://www.ebi.ac.uk/efo/EFO_0010139 GCST011499 Genome-wide genotyping array 13739 2021-05-24 32897244 Zhang L 2020-09-07 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/32897244 Identification of cardiovascular health gene variants related to longevity in a Chinese population. Longevity 395 Chinese ancestry cases, 301 Chinese ancestry controls 4,712 Chinese ancestry cases, 7,867 Chinese ancestry controls Affymetrix [5600000] 0 longevity http://www.ebi.ac.uk/efo/EFO_0004300 GCST011719 Genome-wide genotyping array 696 2020-12-10 32999390 Trajanoska K 2020-09-30 Commun Biol www.ncbi.nlm.nih.gov/pubmed/32999390 Genetic basis of falling risk susceptibility in the UK Biobank Study. Falling risk 89,076 European ancestry cases, 362,103 European ancestry controls 2,215 cases, 6289 controls Affymetrix [7745390] (imputed) 16 Postural instability http://purl.obolibrary.org/obo/HP_0002172 GCST90012857 Genome-wide genotyping array 451179 2018-08-03 29650764 McDonough CW 2018-04-01 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/29650764 Genetic Variants Influencing Plasma Renin Activity in Hypertensive Patients From the PEAR Study (Pharmacogenomic Evaluation of Antihypertensive Responses). Plasma renin activity levels 461 European ancestry individuals, 297 African American ancestry individuals 150 European ancestry individuals Illumina [up to 1000000] (imputed) 3 plasma renin activity measurement http://www.ebi.ac.uk/efo/EFO_0006828 GCST006043 Genome-wide genotyping array 758 2021-04-20 33587031 Sinnott-Armstrong N 2021-02-15 Elife www.ncbi.nlm.nih.gov/pubmed/33587031 GWAS of three molecular traits highlights core genes and pathways alongside a highly polygenic background. Urate levels 318,526 British ancestry individuals NA NR [16000000] (imputed) 299 urate measurement http://www.ebi.ac.uk/efo/EFO_0004531 GCST011521 Genome-wide genotyping array 318526 2021-04-20 33587031 Sinnott-Armstrong N 2021-02-15 Elife www.ncbi.nlm.nih.gov/pubmed/33587031 GWAS of three molecular traits highlights core genes and pathways alongside a highly polygenic background. Insulin-like growth factor 1 levels 317,114 British ancestry individuals NA NR [16000000] (imputed) 402 insulin like growth factor measurement http://www.ebi.ac.uk/efo/EFO_0004628 GCST011520 Genome-wide genotyping array 317114 2021-04-20 33587031 Sinnott-Armstrong N 2021-02-15 Elife www.ncbi.nlm.nih.gov/pubmed/33587031 GWAS of three molecular traits highlights core genes and pathways alongside a highly polygenic background. Testosterone levels 142,778 British ancestry women NA NR [16000000] (imputed) 79 testosterone measurement http://www.ebi.ac.uk/efo/EFO_0004908 GCST011519 Genome-wide genotyping array 142778 2021-04-20 33587031 Sinnott-Armstrong N 2021-02-15 Elife www.ncbi.nlm.nih.gov/pubmed/33587031 GWAS of three molecular traits highlights core genes and pathways alongside a highly polygenic background. Testosterone levels 146,339 British ancestry men NA NR [16000000] (imputed) 130 testosterone measurement http://www.ebi.ac.uk/efo/EFO_0004908 GCST011518 Genome-wide genotyping array 146339 2018-05-21 29534301 Nishida N 2018-03-13 Hepatology www.ncbi.nlm.nih.gov/pubmed/29534301 Key HLA-DRB1-DQB1 haplotypes and role of the BTNL2 gene for response to a hepatitis B vaccine. Response to hepatitis B vaccine 107 Japanese ancestry low responder individuals, 351 Japanese ancestry intermediate responder individuals, 735 Japanese ancestry high responder individuals NA Affymetrix [427664] 20 response to vaccine http://www.ebi.ac.uk/efo/EFO_0004645 GCST005606 Genome-wide genotyping array 1193 2019-01-28 29555444 Hamer MA 2018-03-16 J Invest Dermatol www.ncbi.nlm.nih.gov/pubmed/29555444 Facial Wrinkles in Europeans: a Genome-Wide Association Study. Facial wrinkles 3,513 north-western European ancestry individuals 599 north-western European ancestry individuals Illumina [9009554] (imputed) 19 Facial wrinkling http://purl.obolibrary.org/obo/HP_0009762 GCST006981 Genome-wide genotyping array 3513 2018-06-29 29547969 Chen X 2018-03-14 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/29547969 A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relation to chronic lymphocytic leukemia. Immunoglobulin M against phosphorylcholine (IgM anti-PC) levels 3,002 European ancestry individuals 646 European ancestry individuals Illumina [NR] (imputed) 1 serum IgM measurement http://www.ebi.ac.uk/efo/EFO_0004993 GCST005761 Genome-wide genotyping array 3002 2018-08-03 27479909 Hyde CL 2016-08-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/27479909 Identification of 15 genetic loci associated with risk of major depression in individuals of European descent. Major depressive disorder 84,847 European ancestry cases, 241,266 European ancestry controls 45,773 European ancestry cases, 106,354 European ancestry controls Illumina [1220000] (imputed) 47 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST006041 Genome-wide genotyping array 326113 2018-05-25 29731509 Zabaneh D 2017-07-04 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/29731509 A genome-wide association study for extremely high intelligence. Extremely high intelligence 1,238 European ancestry cases, 8,172 European ancestry controls NA Illumina [6773587] (imputed) 1 intelligence http://www.ebi.ac.uk/efo/EFO_0004337 GCST005626 Genome-wide genotyping array 9410 2018-10-19 30120336 Kikuchi M 2018-08-17 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30120336 Genome-wide Association Analysis of Eye Movement Dysfunction in Schizophrenia. Eye movement (horizontal position gain) 166 Japanese ancestry individuals NA Affymetrix [554152] 1 eye movement measurement http://www.ebi.ac.uk/efo/EFO_0007699 GCST006458 Genome-wide genotyping array 166 2018-10-19 30120336 Kikuchi M 2018-08-17 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30120336 Genome-wide Association Analysis of Eye Movement Dysfunction in Schizophrenia. Eye movement in schizophrenia (scanpath length) 60 Japanese ancestry cases NA Affymetrix [554152] 0 eye movement measurement http://www.ebi.ac.uk/efo/EFO_0007699 GCST006459 Genome-wide genotyping array 60 2018-10-19 30120336 Kikuchi M 2018-08-17 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30120336 Genome-wide Association Analysis of Eye Movement Dysfunction in Schizophrenia. Eye movement (horizontal position gain) 60 Japanese ancestry schizophrenia cases, 166 Japanese ancestry controls NA Affymetrix [554152] 1 eye movement measurement http://www.ebi.ac.uk/efo/EFO_0007699 GCST006457 Genome-wide genotyping array 226 2018-10-19 30120336 Kikuchi M 2018-08-17 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30120336 Genome-wide Association Analysis of Eye Movement Dysfunction in Schizophrenia. Eye movement (scanpath length) 166 Japanese ancestry individuals NA Affymetrix [554152] 0 eye movement measurement http://www.ebi.ac.uk/efo/EFO_0007699 GCST006456 Genome-wide genotyping array 166 2018-10-19 30120336 Kikuchi M 2018-08-17 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30120336 Genome-wide Association Analysis of Eye Movement Dysfunction in Schizophrenia. Eye movement (scanpath length) 60 Japanese ancestry schizophrenia cases, 166 Japanese ancestry controls NA Affymetrix [554152] 0 eye movement measurement http://www.ebi.ac.uk/efo/EFO_0007699 GCST006455 Genome-wide genotyping array 226 2018-10-18 30120336 Kikuchi M 2018-08-17 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30120336 Genome-wide Association Analysis of Eye Movement Dysfunction in Schizophrenia. Eye movement in schizophrenia (duration of fixations) 60 Japanese ancestry cases NA Affymetrix [554152] 0 eye movement measurement http://www.ebi.ac.uk/efo/EFO_0007699 GCST006454 Genome-wide genotyping array 60 2018-10-19 30120336 Kikuchi M 2018-08-17 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30120336 Genome-wide Association Analysis of Eye Movement Dysfunction in Schizophrenia. Eye movement (duration of fixations) 166 Japanese ancestry individuals NA Affymetrix [554152] 0 eye movement measurement http://www.ebi.ac.uk/efo/EFO_0007699 GCST006453 Genome-wide genotyping array 166 2018-10-19 30120336 Kikuchi M 2018-08-17 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30120336 Genome-wide Association Analysis of Eye Movement Dysfunction in Schizophrenia. Eye movement (duration of fixations) 60 Japanese ancestry schizophrenia cases, 166 Japanese ancestry controls NA Affymetrix [554152] 0 eye movement measurement http://www.ebi.ac.uk/efo/EFO_0007699 GCST006452 Genome-wide genotyping array 226 2018-10-19 30120336 Kikuchi M 2018-08-17 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30120336 Genome-wide Association Analysis of Eye Movement Dysfunction in Schizophrenia. Eye movement in schizophrenia (integrated eye movement score) 60 Japanese ancestry cases NA Affymetrix [554152] 0 eye movement measurement http://www.ebi.ac.uk/efo/EFO_0007699 GCST006451 Genome-wide genotyping array 60 2018-10-19 30120336 Kikuchi M 2018-08-17 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30120336 Genome-wide Association Analysis of Eye Movement Dysfunction in Schizophrenia. Eye movement (integrated eye movement score) 166 Japanese ancestry individuals NA Affymetrix [554152] 0 eye movement measurement http://www.ebi.ac.uk/efo/EFO_0007699 GCST006450 Genome-wide genotyping array 166 2018-10-19 30120336 Kikuchi M 2018-08-17 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30120336 Genome-wide Association Analysis of Eye Movement Dysfunction in Schizophrenia. Eye movement (integrated eye movement score) 60 Japanese ancestry schizophrenia cases, 166 Japanese ancestry controls NA Affymetrix [554152] 0 eye movement measurement http://www.ebi.ac.uk/efo/EFO_0007699 GCST006449 Genome-wide genotyping array 226 2018-10-19 30120336 Kikuchi M 2018-08-17 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30120336 Genome-wide Association Analysis of Eye Movement Dysfunction in Schizophrenia. Eye movement in schizophrenia (horizontal position gain) 60 Japanese ancestry cases NA Affymetrix [554152] 3 eye movement measurement http://www.ebi.ac.uk/efo/EFO_0007699 GCST006448 Genome-wide genotyping array 60 2018-11-30 30279531 Baselmans BML 2018-10-02 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30279531 A genetic perspective on the relationship between eudaimonic -and hedonic well-being. Eudaimonic well-being 108,154 British ancestry individuals NA Affymetrix [~ 8600000] (imputed) 21 wellbeing measurement http://www.ebi.ac.uk/efo/EFO_0007869 GCST006635 Genome-wide genotyping array 108154 2018-11-30 30279531 Baselmans BML 2018-10-02 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30279531 A genetic perspective on the relationship between eudaimonic -and hedonic well-being. Hedonic well-being 221,575 British ancestry individuals NA Affymetrix [~ 8600000] (imputed) 6 wellbeing measurement http://www.ebi.ac.uk/efo/EFO_0007869 GCST006634 Genome-wide genotyping array 221575 2018-07-19 29662059 Howard DM 2018-04-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29662059 Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways. Major depressive disorder (probable) 30,603 British ancestry cases, 143,916 British ancestry controls NA NR [7666894] (imputed) 9 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST005904 Genome-wide genotyping array 174519 2018-07-19 29662059 Howard DM 2018-04-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29662059 Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways. Major depressive disorder (ICD-10 coded) 8,276 British ancestry cases, 209,308 British ancestry controls NA NR [7666894] (imputed) 4 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST005903 Genome-wide genotyping array 217584 2018-07-19 29662059 Howard DM 2018-04-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29662059 Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways. Depression (broad) 113,769 British ancestry cases, 208,811 British ancestry controls NA NR [7666894] (imputed) 111 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST005902 Genome-wide genotyping array 322580 2018-12-19 30304924 Kim HJ 2018-06-30 Genomics Inform www.ncbi.nlm.nih.gov/pubmed/30304924 Identification of LEF1 as a Susceptibility Locus for Kawasaki Disease in Patients Younger than 6 Months of Age. Kawasaki disease 296 Korean ancestry cases, 1,000 Korean ancestry controls 2,666 East Asian ancestry cases, 10,446 East Asian ancestry controls Illumina [NR] 0 mucocutaneous lymph node syndrome http://www.ebi.ac.uk/efo/EFO_0004246 GCST006809 Genome-wide genotyping array 1296 2018-11-30 30294719 Zeng Y 2018-08-24 JAMA Netw Open www.ncbi.nlm.nih.gov/pubmed/30294719 Sex Differences in Genetic Associations With Longevity. Longevity 564 Han Chinese ancestry male centenarian cases, 1,614 Han Chinese ancestry female centenarian cases, 773 Han Chinese ancestry male middle-aged controls, 1,526 Han Chinese ancestry female middle-aged controls NA Illumina [5595657] (imputed) 20 longevity http://www.ebi.ac.uk/efo/EFO_0004300 GCST006658 Genome-wide genotyping array 4477 2019-02-21 30299488 Wang TM 2018-10-08 J Natl Cancer Inst www.ncbi.nlm.nih.gov/pubmed/30299488 Genome-Wide Association Study of Susceptibility Loci for Radiation-Induced Brain Injury. Radiation-induced brain injury in nasopharyngeal carcinoma 243 cases, 839 controls 438 cases, 1,422 controls Illumina [445078] 2 response to radiation, radiation-induced brain injury http://purl.obolibrary.org/obo/GO_0009314, http://www.ebi.ac.uk/efo/EFO_0009704 GCST007200 Genome-wide genotyping array 1082 2019-05-07 30651383 Chauhan G 2019-01-16 Neurology www.ncbi.nlm.nih.gov/pubmed/30651383 Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. Small subcortical brain infarct 1,715 European ancestry cases, 187 African American cases, 56 Hispanic ancestry cases, 23 Chinese ancestry cases, 40 Malay ancestry cases, 13,749 European ancestry controls, 807 African American controls, 643 Hispanic ancestry controls, 173 Chinese ancestry controls, 168 Malay ancestry controls 630 European ancestry cases, 5,118 European ancestry controls Affymetrix, Illumina [6824387] (imputed) 0 MRI defined brain infarct http://www.ebi.ac.uk/efo/EFO_0004715 GCST007729 Genome-wide genotyping array 17561 2019-05-07 30651383 Chauhan G 2019-01-16 Neurology www.ncbi.nlm.nih.gov/pubmed/30651383 Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. Brain infarct 3,149 European ancestry cases, 402 African American cases, 94 Hispanic ancestry cases, 34 Chinese ancestry cases, 47 Malay ancestry cases, 14,807 European ancestry controls, 1,432 African American controls, 643 Hispanic ancestry controls, 173 Chinese ancestry controls, 168 Malay ancestry controls 1,223 European ancestry cases, 260 Japanese ancestry cases, 5,118 European ancestry controls, 261 Japanese ancestry controls Affymetrix, Illumina [7423334] (imputed) 0 MRI defined brain infarct http://www.ebi.ac.uk/efo/EFO_0004715 GCST007730 Genome-wide genotyping array 20949 2019-02-06 29520040 Coleman JRI 2018-03-08 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/29520040 Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals. Extremely high intelligence 1,247 European ancestry cases, 86,493 European ancestry controls NA Illumina [up to 12595966] (imputed) 25 intelligence http://www.ebi.ac.uk/efo/EFO_0004337 GCST007044 Genome-wide genotyping array 87740 2019-03-27 30729179 Zenin A 2019-01-30 Commun Biol www.ncbi.nlm.nih.gov/pubmed/30729179 Identification of 12 genetic loci associated with human healthspan. Healthspan 300,447 British ancestry individuals 81,099 European ancestry individuals, 3,073 African ancestry individuals, 6,921 South Asian ancestry individuals, 1,422 Chinese ancestry individuals, 3,799 Caribbean individuals Affymetrix [11309218] (imputed) 2 healthspan http://www.ebi.ac.uk/efo/EFO_0009762 GCST007406 Genome-wide genotyping array 300447 2018-09-28 30045251 Lee MR 2018-07-01 Medicine (Baltimore) www.ncbi.nlm.nih.gov/pubmed/30045251 Causal association of body mass index with hypertension using a Mendelian randomization design. Body mass index 8,832 Korean ancestry individuals NA Affymetrix [1590162] (imputed) 10 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST006369 Genome-wide genotyping array 8832 2018-10-18 30108155 Hebbar P 2018-08-14 J Lipid Res www.ncbi.nlm.nih.gov/pubmed/30108155 Genome-wide association study identifies novel recessive genetic variants for high TGs in an Arab population. High density lipoprotein cholesterol levels 1,353 Kuwaiti ancestry individuals 1,176 Kuwaiti ancestry individuals Illumina [632375] 2 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST006438 Genome-wide genotyping array 1353 2018-10-18 30108155 Hebbar P 2018-08-14 J Lipid Res www.ncbi.nlm.nih.gov/pubmed/30108155 Genome-wide association study identifies novel recessive genetic variants for high TGs in an Arab population. Low density lipoprotein cholesterol levels 1,353 Kuwaiti ancestry individuals 1,176 Kuwaiti ancestry individuals Illumina [632375] 0 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST006437 Genome-wide genotyping array 1353 2018-10-18 30108155 Hebbar P 2018-08-14 J Lipid Res www.ncbi.nlm.nih.gov/pubmed/30108155 Genome-wide association study identifies novel recessive genetic variants for high TGs in an Arab population. Total cholesterol levels 1,353 Kuwaiti ancestry individuals 1,176 Kuwaiti ancestry individuals Illumina [632375] 0 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST006439 Genome-wide genotyping array 1353 2018-10-18 30108155 Hebbar P 2018-08-14 J Lipid Res www.ncbi.nlm.nih.gov/pubmed/30108155 Genome-wide association study identifies novel recessive genetic variants for high TGs in an Arab population. Triglyceride levels 1,353 Kuwaiti ancestry individuals 1,176 Kuwaiti ancestry individuals Illumina [632375] 15 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST006436 Genome-wide genotyping array 1353 2021-03-29 32758111 He M 2020-08-06 J Dent Res www.ncbi.nlm.nih.gov/pubmed/32758111 Genome-wide Analyses Identify a Novel Risk Locus for Nonsyndromic Cleft Palate. Nonsyndromic cleft palate 994 Han Chinese ancestry cases, 2,963 Han Chinese ancestry controls 1,095 Han Chinese ancestry cases, 6,352 Han Chinese ancestry controls Illumina [750091] 5 Cleft palate http://purl.obolibrary.org/obo/HP_0000175 GCST011425 Genome-wide genotyping array 3957 2018-07-19 29728651 Li X 2018-04-27 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/29728651 Common variants on 6q16.2, 12q24.31 and 16p13.3 are associated with major depressive disorder. Major depressive disorder 84,847 European ancestry cases, 241,266 European ancestry controls, 5,303 Han Chinese ancestry cases, 5,337 Han Chinese ancestry controls 2,659 European ancestry cases, 17,237 European ancestry controls Affymetrix, Illumina [at least 1235109] (imputed) 13 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST005907 Genome-wide genotyping array 336753 2018-09-11 29730043 Li J 2018-05-02 Schizophr Res www.ncbi.nlm.nih.gov/pubmed/29730043 Identifying the genetic risk factors for treatment response to lurasidone by genome-wide association study: A meta-analysis of samples from three independent clinical trials. Response to lurasidone in schizophrenia 264 European ancestry cases, 158 African American ancestry cases NA Affymetrix, Illumina [up to 1994688] 13 response to antipsychotic drug http://purl.obolibrary.org/obo/GO_0097332 GCST006248 Genome-wide genotyping array 422 2018-06-06 29728394 Blauw LL 2018-05-01 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/29728394 CETP (Cholesteryl Ester Transfer Protein) Concentration: A Genome-Wide Association Study Followed by Mendelian Randomization on Coronary Artery Disease. Cholesteryl ester transfer protein levels 4248 individuals 1458 individuals Illumina [NR] (imputed) 3 cholesteryl ester transfer protein measurement http://www.ebi.ac.uk/efo/EFO_0009133 GCST005672 Genome-wide genotyping array 4248 2018-06-21 29725004 Hosoda Y 2018-05-03 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29725004 CCDC102B confers risk of low vision and blindness in high myopia. Myopic maculopathy 4,476 Japanese ancestry individuals 3,279 Japanese ancestry individuals Illumina [4710779] (imputed) 1 myopic maculopathy severity measurement http://www.ebi.ac.uk/efo/EFO_0009177 GCST005715 Genome-wide genotyping array, Exome genotyping array 4476 2018-10-19 30093612 O'Mara TA 2018-08-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30093612 Identification of nine new susceptibility loci for endometrial cancer. Endometrial cancer (endometrioid histology) 8,758 European ancestry cases, 46,126 European ancestry controls NA Affymetrix, Illumina [~ 11700000] (imputed) 32 endometrial carcinoma http://www.ebi.ac.uk/efo/EFO_1001512 GCST006465 Genome-wide genotyping array 54884 2018-10-19 30093612 O'Mara TA 2018-08-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30093612 Identification of nine new susceptibility loci for endometrial cancer. Endometrial cancer (Non-endometrioid histology) 1,230 European ancestry cases, 35,447 European ancestry controls NA Affymetrix, Illumina [~ 11700000] (imputed) 7 endometrial carcinoma http://www.ebi.ac.uk/efo/EFO_1001512 GCST006466 Genome-wide genotyping array 36677 2018-10-19 30093612 O'Mara TA 2018-08-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30093612 Identification of nine new susceptibility loci for endometrial cancer. Endometrial cancer 12,906 European ancestry cases, 108,979 European ancestry controls NA Affymetrix, Illumina [~ 11700000] (imputed) 28 endometrial carcinoma http://www.ebi.ac.uk/efo/EFO_1001512 GCST006464 Genome-wide genotyping array 121885 2019-03-18 30643256 Baselmans BML 2019-01-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30643256 Multivariate genome-wide analyses of the well-being spectrum. Life satisfaction 80,852 European ancestry individuals NA NR [NR] 148 wellbeing measurement http://www.ebi.ac.uk/efo/EFO_0007869 GCST007337 Genome-wide genotyping array 80852 2019-03-18 30643256 Baselmans BML 2019-01-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30643256 Multivariate genome-wide analyses of the well-being spectrum. Positive affect 410,603 European ancestry individuals NA NR [NR] 191 wellbeing measurement http://www.ebi.ac.uk/efo/EFO_0007869 GCST007338 Genome-wide genotyping array 410603 2019-03-18 30643256 Baselmans BML 2019-01-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30643256 Multivariate genome-wide analyses of the well-being spectrum. Neuroticism 523,783 European ancestry individuals 59,206 European ancestry individuals NR [NR] 263 neuroticism measurement http://www.ebi.ac.uk/efo/EFO_0007660 GCST007339 Genome-wide genotyping array 523783 2019-03-18 30643256 Baselmans BML 2019-01-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30643256 Multivariate genome-wide analyses of the well-being spectrum. Depressive symptoms 1,067,913 European ancestry individuals 228,033 European ancestry individuals NR [NR] 239 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST007340 Genome-wide genotyping array 1067913 2019-03-18 30643256 Baselmans BML 2019-01-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30643256 Multivariate genome-wide analyses of the well-being spectrum. Well-being spectrum (multivariate analysis) 2,083,151 European ancestry individuals 287,239 European ancestry individuals NR [NR] 231 wellbeing measurement http://www.ebi.ac.uk/efo/EFO_0007869 GCST007341 Genome-wide genotyping array 2083151 2019-01-28 30305637 McMaster ML 2018-10-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30305637 Two high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenström macroglobulinemia. Waldenström macroglobulinemia / lymphoplasmacytic lymphoma 217 European ancestry cases, 3,798 European ancestry controls 313 European ancestry cases, 564 European ancestry controls Illumina [6440053] (imputed) 3 Waldenstrom macroglobulinemia http://www.ebi.ac.uk/efo/EFO_0009441 GCST006982 Genome-wide genotyping array 4015 2018-12-14 30305740 Elliott LT 2018-10-10 Nature www.ncbi.nlm.nih.gov/pubmed/30305740 Genome-wide association studies of brain imaging phenotypes in UK Biobank. Brain imaging measurements 8,428 British ancestry individuals 4,386 European ancestry individuals NR [11734353] (imputed) 6 neuroimaging measurement http://www.ebi.ac.uk/efo/EFO_0004346 GCST006777 Genome-wide genotyping array 8428 2019-02-13 30298529 Stanaway IB 2018-10-08 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30298529 The eMERGE genotype set of 83,717 subjects imputed to ~40 million variants genome wide and association with the herpes zoster medical record phenotype. Shingles 3,201 European ancestry cases, 34,960 European ancestry controls, 398 African American cases, 5,922 African American controls, 756 Asian ancestry individuals NA Affymetrix, Illumina [39127678] (imputed) 11 Herpes Zoster http://www.ebi.ac.uk/efo/EFO_0006510 GCST007139 Genome-wide genotyping array 45237 2019-01-16 30305239 Macias-Kauffer LR 2018-10-01 Int J Cardiol www.ncbi.nlm.nih.gov/pubmed/30305239 Genetic contributors to serum uric acid levels in Mexicans and their effect on premature coronary artery disease. Serum uric acid levels 2153 Mexican ancestry individuals NA Illumina [865896] (imputed) 3 uric acid measurement http://www.ebi.ac.uk/efo/EFO_0004761 GCST006905 Genome-wide genotyping array 2153 2019-05-07 28817678 Archer NP 2017-08-17 PLoS One www.ncbi.nlm.nih.gov/pubmed/28817678 Family-based exome-wide association study of childhood acute lymphoblastic leukemia among Hispanics confirms role of ARID5B in susceptibility. Acute lymphoblastic leukemia (childhood) 203 Hispanic cases and 96 Native American cases from 323 families NA Illumina [up to 237436] 2 acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000220 GCST007727 Targeted genotyping array [Exome array] 622 2019-01-25 26490195 Cleynen I 2015-10-18 Lancet www.ncbi.nlm.nih.gov/pubmed/26490195 Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study. Inflammatory bowel disease 16,902 European ancestry Crohn's disease cases, 12,597 European ancestry ulcerative colitis cases, 339 European ancestry cases 2,453 European ancestry Crohn's disease cases, 3,729 European ancestry ulcerative colitis cases Illumina [156154] (imputed) 0 inflammatory bowel disease http://www.ebi.ac.uk/efo/EFO_0003767 GCST006960 Targeted genotyping array [ImmunoChip] 29838 2018-10-17 30116032 Erlangsen A 2018-08-16 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30116032 Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study. Suicide attempts 6,024 European ancestry cases, 44,240 European ancestry controls NA Illumina [11601089] (imputed) 10 attempted suicide http://www.ebi.ac.uk/efo/EFO_0004321 GCST006419 Genome-wide genotyping array 50264 2018-10-17 30116032 Erlangsen A 2018-08-16 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30116032 Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study. Affective disorder and suicide attempts 4,302 European ancestry cases, 13,294 European ancestry population controls NA Illumina [11601089] (imputed) 7 attempted suicide, mood disorder http://www.ebi.ac.uk/efo/EFO_0004321, http://www.ebi.ac.uk/efo/EFO_0004247 GCST006420 Genome-wide genotyping array 17596 2018-07-10 29632299 Vijayakrishnan J 2018-04-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/29632299 Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia. Acute lymphoblastic leukemia in childhood (B cell precursor) 2,442 European ancestry cases, 14,609 European ancestry controls NA Illumina [6755715] (imputed) 11 B-cell acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000094 GCST005832 Genome-wide genotyping array 17051 2018-07-13 29632305 Lee HS 2018-04-09 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29632305 New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population. Metabolic syndrome (multivariate analysis) 1,946 Korean ancestry cases, 6,427 Korean ancestry controls 430 Korean ancestry cases, 3,264 Korean ancestry controls Affymetrix [344366] 10 metabolic syndrome http://www.ebi.ac.uk/efo/EFO_0000195 GCST005878 Genome-wide genotyping array 8373 2019-04-03 30166351 Galvan-Femenia I 2018-08-30 J Med Genet www.ncbi.nlm.nih.gov/pubmed/30166351 Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort. Anthropometric traits (multi-trait analysis) 4,988 Spanish ancestry individuals 336,107 British ancestry individuals Illumina [9499600] (imputed) 29 body weights and measures http://www.ebi.ac.uk/efo/EFO_0004324 GCST007490 Genome-wide genotyping array 4988 2019-04-03 30166351 Galvan-Femenia I 2018-08-30 J Med Genet www.ncbi.nlm.nih.gov/pubmed/30166351 Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort. Anthropometric traits 4,988 Spanish ancestry individuals 336,107 British ancestry individuals Illumina [9499600] (imputed) 15 body weights and measures http://www.ebi.ac.uk/efo/EFO_0004324 GCST007485 Genome-wide genotyping array 4988 2019-04-02 30166351 Galvan-Femenia I 2018-08-30 J Med Genet www.ncbi.nlm.nih.gov/pubmed/30166351 Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort. Disorders of lipid metabolism 4,988 Spanish ancestry individuals NA Illumina [9499600] (imputed) 1 Abnormal circulating lipid concentration http://purl.obolibrary.org/obo/HP_0003119 GCST007480 Genome-wide genotyping array 4988 2019-04-03 30166351 Galvan-Femenia I 2018-08-30 J Med Genet www.ncbi.nlm.nih.gov/pubmed/30166351 Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort. Eye color traits 4,988 Spanish ancestry individuals NA Illumina [9499600] (imputed) 13 eye color http://www.ebi.ac.uk/efo/EFO_0003949 GCST007489 Genome-wide genotyping array 4988 2019-04-03 30166351 Galvan-Femenia I 2018-08-30 J Med Genet www.ncbi.nlm.nih.gov/pubmed/30166351 Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort. Skin pigmentation traits 4,988 Spanish ancestry individuals NA Illumina [9499600] (imputed) 43 skin pigmentation http://www.ebi.ac.uk/efo/EFO_0003784 GCST007488 Genome-wide genotyping array 4988 2019-04-03 30166351 Galvan-Femenia I 2018-08-30 J Med Genet www.ncbi.nlm.nih.gov/pubmed/30166351 Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort. Hair morphology traits 4,988 Spanish ancestry individuals NA Illumina [9499600] (imputed) 33 hair morphology measurement http://www.ebi.ac.uk/efo/EFO_0007821 GCST007486 Genome-wide genotyping array 4988 2019-04-02 30166351 Galvan-Femenia I 2018-08-30 J Med Genet www.ncbi.nlm.nih.gov/pubmed/30166351 Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort. Handedness 4,988 Spanish ancestry individuals NA Illumina [9499600] (imputed) 1 handedness http://www.ebi.ac.uk/efo/EFO_0009902 GCST007482 Genome-wide genotyping array 4988 2019-04-02 30166351 Galvan-Femenia I 2018-08-30 J Med Genet www.ncbi.nlm.nih.gov/pubmed/30166351 Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort. Heart rate 4,988 Spanish ancestry individuals NA Illumina [9499600] (imputed) 1 heart rate http://www.ebi.ac.uk/efo/EFO_0004326 GCST007481 Genome-wide genotyping array 4988 2018-07-11 29631748 McCoy TH Jr. 2018-03-10 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/29631748 Genome-wide association identifies a novel locus for delirium risk. Delirium 421 European ancestry cases, 5,614 European ancestry controls NA Illumina [up to 1747639] (imputed) 27 delirium http://www.ebi.ac.uk/efo/EFO_0009267 GCST005851 Genome-wide genotyping array 6035 2019-02-12 30297428 Jorgenson E 2018-10-08 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/30297428 Genetic variation in the SIM1 locus is associated with erectile dysfunction. Erectile dysfunction 11,864 European ancestry cases, 1,016 Hispanic cases, 938 East Asian ancestry cases, 397 African American cases, 17,995 European ancestry controls, 1,954 Hispanic controls, 1,799 East Asian ancestry controls, 686 African American controls 2,783 European ancestry cases, 70 South Asian ancestry cases, 68 African British cases, 2 East Asian ancestry cases, 36 mixed and unknown ancestry cases, 206,975 European ancestry controls, 5,234 South Asian ancestry controls, 3,566 African British controls, 678 East Asian ancestry controls, 3,626 mixed and unknown ancestry controls Affymetrix [665000] 1 erectile dysfunction http://www.ebi.ac.uk/efo/EFO_0004234 GCST007118 Genome-wide genotyping array 36649 2018-11-26 30166627 Massey J 2018-08-31 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/30166627 Genome-wide association study of response to tumour necrosis factor inhibitor therapy in rheumatoid arthritis. Response to TNF inhibitor in rheumatoid arthritis (erythrocyte sedimentation rate) 487 European ancestry individuals treated with adalimumab, 549 European ancestry individuals treated with etanercept, 414 European ancestry individuals treated with infliximab, 64 European ancestry individuals treated with other TNF inhibitors NA Affymetrix, Illumina [9814288] (imputed) 1 response to TNF antagonist, blood sedimentation http://www.ebi.ac.uk/efo/EFO_0004653, http://www.ebi.ac.uk/efo/EFO_0004304 GCST006607 Genome-wide genotyping array 1514 2018-11-26 30166627 Massey J 2018-08-31 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/30166627 Genome-wide association study of response to tumour necrosis factor inhibitor therapy in rheumatoid arthritis. Response to TNF inhibitor in rheumatoid arthritis (change in swollen 28-joint count) 551 European ancestry individuals treated with adalimumab, 619 European ancestry individuals treated with etanercept, 434 European ancestry individuals treated with infliximab, 119 European ancestry individuals treated with other TNF inhibitors NA Affymetrix, Illumina [9814288] (imputed) 13 response to TNF antagonist, joint damage measurement http://www.ebi.ac.uk/efo/EFO_0004653, http://www.ebi.ac.uk/efo/EFO_0005413 GCST006606 Genome-wide genotyping array 1723 2018-11-26 30166627 Massey J 2018-08-31 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/30166627 Genome-wide association study of response to tumour necrosis factor inhibitor therapy in rheumatoid arthritis. Response to TNF inhibitor in rheumatoid arthritis (change in patient global heath assessment score) 549 European ancestry individuals treated with adalimumab, 615 European ancestry individuals treated with etanercept, 426 European ancestry individuals treated with infliximab, 119 European ancestry individuals treated with other TNF inhibitors NA Affymetrix, Illumina [9814288] (imputed) 1 self rated health, response to TNF antagonist http://www.ebi.ac.uk/efo/EFO_0004778, http://www.ebi.ac.uk/efo/EFO_0004653 GCST006608 Genome-wide genotyping array 1709 2018-11-26 30166627 Massey J 2018-08-31 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/30166627 Genome-wide association study of response to tumour necrosis factor inhibitor therapy in rheumatoid arthritis. Response to TNF inhibitor in rheumatoid arthritis (change in tender 28-joint count) 551 European ancestry individuals treated with adalimumab, 619 European ancestry individuals treated with etanercept, 434 European ancestry individuals treated with infliximab, 119 European ancestry individuals treated with other TNF inhibitors NA Affymetrix, Illumina [9814288] (imputed) 7 response to TNF antagonist, joint damage measurement http://www.ebi.ac.uk/efo/EFO_0004653, http://www.ebi.ac.uk/efo/EFO_0005413 GCST006609 Genome-wide genotyping array 1723 2018-11-26 30166627 Massey J 2018-08-31 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/30166627 Genome-wide association study of response to tumour necrosis factor inhibitor therapy in rheumatoid arthritis. Response to TNF inhibitor in rheumatoid arthritis (change in disease activity score) 500 European ancestry individuals treated with adalimumab, 564 European ancestry individuals treated with etanercept, 441 European ancestry individuals treated with infliximab, 64 European ancestry individuals treated with other TNF inhibitors NA Affymetrix, Illumina [9814288] (imputed) 1 response to TNF antagonist, arthritis disease activity score measurement http://www.ebi.ac.uk/efo/EFO_0004653, http://www.ebi.ac.uk/efo/EFO_0009435 GCST006610 Genome-wide genotyping array 1569 2019-10-29 30305743 Bycroft C 2018-10-10 Nature www.ncbi.nlm.nih.gov/pubmed/30305743 The UK Biobank resource with deep phenotyping and genomic data. Height 343,321 British ancestry individuals 253,288 European ancestry individuals Affymetrix [16443622] (imputed) 0 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST008974 Genome-wide genotyping array 343321 2019-04-24 28346466 Chen G 2017-03-27 PLoS One www.ncbi.nlm.nih.gov/pubmed/28346466 Common and rare exonic MUC5B variants associated with type 2 diabetes in Han Chinese. Type 2 diabetes 1,908 Han Chinese ancestry individuals 10,401 African ancestry individuals Illumina [up to 178943] 0 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST007620 Targeted genotyping array [Exome array] 1908 2019-01-10 23830517 Saruhan-Direskeneli G 2013-07-03 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/23830517 Identification of multiple genetic susceptibility loci in Takayasu arteritis. Takayasu arteritis 305 Turkish ancestry cases, 106 European ancestry cases, 483 Turkish ancestry controls, 553 European ancestry controls NA Illumina [at least 124312] 5 Takayasu arteritis http://www.ebi.ac.uk/efo/EFO_1001857 GCST006863 Targeted genotyping array [ImmunoChip] 1447 2018-09-19 30054556 Akiyama M 2018-07-27 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30054556 Genome-wide association study suggests four variants influencing outcomes with ranibizumab therapy in exudative age-related macular degeneration. Response to ranibizumab in age-related macular degeneration (exudative) 361 Japanese ancestry responder cases, 73 Japanese ancestry non-responder controls 363 Japanese ancestry responder cases, 122 Japanese ancestry non-responder controls Illumina [6826359] (imputed) 4 response to ranibizumab http://www.ebi.ac.uk/efo/EFO_0008348 GCST006277 Genome-wide genotyping array 434 2020-07-22 32276964 Shete S 2020-04-10 Cancer Res www.ncbi.nlm.nih.gov/pubmed/32276964 A genome-wide association study identifies two novel susceptible regions for squamous cell carcinoma of the head and neck. Oral cavity cancer 631 European ancestry cases, 4,493 European ancestry controls 2,568 European ancestry cases, 3,232 European ancestry controls Illumina [7858089] (imputed) 2 oral cavity cancer http://www.ebi.ac.uk/efo/EFO_0005570 GCST010287 Genome-wide genotyping array 5124 2020-07-22 32276964 Shete S 2020-04-10 Cancer Res www.ncbi.nlm.nih.gov/pubmed/32276964 A genome-wide association study identifies two novel susceptible regions for squamous cell carcinoma of the head and neck. Oropharynx cancer 1,144 European ancestry cases, 4,493 European ancestry controls 2,328 European ancestry cases, 3,232 European ancestry controls Illumina [7858089] (imputed) 3 oropharynx cancer http://www.ebi.ac.uk/efo/EFO_1001931 GCST010286 Genome-wide genotyping array 5637 2020-07-22 32276964 Shete S 2020-04-10 Cancer Res www.ncbi.nlm.nih.gov/pubmed/32276964 A genome-wide association study identifies two novel susceptible regions for squamous cell carcinoma of the head and neck. Hypopharyngeal or laryngeal cancer 394 European ancestry cases, 4,493 European ancestry controls 295 European ancestry cases, 3,232 European ancestry controls Illumina [7858089] (imputed) 2 laryngeal squamous cell carcinoma, hypopharynx cancer http://www.ebi.ac.uk/efo/EFO_0006352, http://www.ebi.ac.uk/efo/EFO_0007321 GCST010285 Genome-wide genotyping array 4887 2020-07-22 32276964 Shete S 2020-04-10 Cancer Res www.ncbi.nlm.nih.gov/pubmed/32276964 A genome-wide association study identifies two novel susceptible regions for squamous cell carcinoma of the head and neck. Head and neck squamous cell carcinoma 2,171 European ancestry cases, 4,493 European ancestry controls 5,205 European ancestry cases, 3,232 European ancestry controls Illumina [7858089] (imputed) 3 head and neck squamous cell carcinoma http://www.ebi.ac.uk/efo/EFO_0000181 GCST010288 Genome-wide genotyping array 6664 2019-09-02 31220337 Carr DF 2019-06-20 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/31220337 Genome-wide association study of statin-induced myopathy in patients recruited using the UK clinical practice research datalink. Simvastatin-induced myopathy 85 European ancestry cases, 2,501 controls NA Illumina [654642] (imputed) 28 response to simvastatin, myopathy http://purl.obolibrary.org/obo/GO_1903491, http://www.ebi.ac.uk/efo/EFO_0004145 GCST008551 Genome-wide genotyping array 2586 2019-09-02 31220337 Carr DF 2019-06-20 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/31220337 Genome-wide association study of statin-induced myopathy in patients recruited using the UK clinical practice research datalink. Atorvastatin-induced myopathy 28 European ancestry cases, 2,501 controls NA Illumina [654642] (imputed) 9 response to atorvastatin, myopathy http://www.ebi.ac.uk/efo/EFO_0010124, http://www.ebi.ac.uk/efo/EFO_0004145 GCST008554 Genome-wide genotyping array 2529 2019-09-02 31220337 Carr DF 2019-06-20 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/31220337 Genome-wide association study of statin-induced myopathy in patients recruited using the UK clinical practice research datalink. Statin-induced myopathy (severe) 32 European ancestry cases, 2,501 controls NA Illumina [654642] (imputed) 6 response to statin, myopathy http://purl.obolibrary.org/obo/GO_0036273, http://www.ebi.ac.uk/efo/EFO_0004145 GCST008553 Genome-wide genotyping array 2533 2019-09-02 31220337 Carr DF 2019-06-20 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/31220337 Genome-wide association study of statin-induced myopathy in patients recruited using the UK clinical practice research datalink. Statin-induced myopathy 128 European ancestry cases, 2,501 controls NA Illumina [654642] (imputed) 2 response to statin, myopathy http://purl.obolibrary.org/obo/GO_0036273, http://www.ebi.ac.uk/efo/EFO_0004145 GCST008552 Genome-wide genotyping array 2629 2021-08-13 33527407 Truong T 2021-02-02 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/33527407 Multiethnic genome-wide association study of differentiated thyroid cancer in the EPITHYR consortium. Differentiated thyroid cancer 1,554 European ancestry cases, 1,973 European ancestry controls 2,229 European ancestry cases, 2,059 European ancestry controls Illumina [9673063] (imputed) 8 differentiated thyroid carcinoma http://www.ebi.ac.uk/efo/EFO_1002017 GCST012197 Genome-wide genotyping array 3527 2021-08-13 33527407 Truong T 2021-02-02 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/33527407 Multiethnic genome-wide association study of differentiated thyroid cancer in the EPITHYR consortium. Differentiated thyroid cancer 301 Oceanian ancestry cases, 348 Oceanian ancestry controls NA Illumina [7179638] (imputed) 0 differentiated thyroid carcinoma http://www.ebi.ac.uk/efo/EFO_1002017 GCST012196 Genome-wide genotyping array 649 2021-08-13 33527407 Truong T 2021-02-02 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/33527407 Multiethnic genome-wide association study of differentiated thyroid cancer in the EPITHYR consortium. Differentiated thyroid cancer 1,554 European ancestry cases, 1,973 European ancestry controls, 301 Oceanian ancestry cases, 348 Oceanian ancestry controls NA Illumina [6479975] (imputed) 11 differentiated thyroid carcinoma http://www.ebi.ac.uk/efo/EFO_1002017 GCST012195 Genome-wide genotyping array 4176 2021-08-13 33517400 Ahluwalia TS 2021-01-30 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33517400 Genome-Wide Association Study of Circulating Interleukin 6 Levels Identifies Novel Loci. Interleukin-6 levels 52,654 European ancestry individuals 14,774 European ancestry individuals Affymetrix, Illumina, Perlegen [2454025] (imputed) 9 interleukin-6 measurement http://www.ebi.ac.uk/efo/EFO_0004810 GCST012198 Genome-wide genotyping array 52654 2019-08-22 31345160 Jia H 2019-07-26 BMC Genet www.ncbi.nlm.nih.gov/pubmed/31345160 GWAS of habitual coffee consumption reveals a sex difference in the genetic effect of the 12q24 locus in the Japanese population. Coffee consumption 6,264 Japanese ancestry individuals 5,975 Japanese ancestry individuals Illumina [5264155] (imputed) 3 coffee consumption measurement http://www.ebi.ac.uk/efo/EFO_0006781 GCST008487 Genome-wide genotyping array 6264 2021-03-29 32771030 Tangtanatakul P 2020-08-08 Arthritis Res Ther www.ncbi.nlm.nih.gov/pubmed/32771030 Meta-analysis of genome-wide association study identifies FBN2 as a novel locus associated with systemic lupus erythematosus in Thai population. Systemic lupus erythematosus 487 Thai cases, 1,606 Thai controls 405 Thai cases, 1,590 Thai controls Illumina [421909] (imputed) 38 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST011426 Genome-wide genotyping array 2093 2019-09-24 31358974 Evangelou E 2019-07-29 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/31358974 New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders. Alcohol consumption 480,842 European ancestry individuals NA Affymetrix, Illumina [~ 7100000] (imputed) 51 alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0007878 GCST008757 Genome-wide genotyping array 480842 2019-09-13 31467194 Ganna A 2019-08-01 Science www.ncbi.nlm.nih.gov/pubmed/31467194 Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior. same-sex sexual behaviour 329,546 European ancestry males 2,196 European ancestry males, up to 9,109 European ancestry twins Affymetrix, Illumina [NR] (imputed) 0 same-sex sexual behavior http://www.ebi.ac.uk/efo/EFO_0010142 GCST008652 Genome-wide genotyping array 329546 2019-09-13 31467194 Ganna A 2019-08-01 Science www.ncbi.nlm.nih.gov/pubmed/31467194 Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior. same-sex sexual behaviour 338,218 European ancestry females 2,529 European ancestry females, up to 9,109 European ancestry twins Affymetrix, Illumina [NR] (imputed) 0 same-sex sexual behavior http://www.ebi.ac.uk/efo/EFO_0010142 GCST008653 Genome-wide genotyping array 338218 2019-09-13 31467194 Ganna A 2019-08-01 Science www.ncbi.nlm.nih.gov/pubmed/31467194 Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior. same-sex sexual behaviour 329,546 European ancestry males, 338,218 European ancestry females 2,196 European ancestry males, 2,529 European ancestry females, 9,109European ancestry twins Affymetrix, Illumina [NR] (imputed) 0 same-sex sexual behavior http://www.ebi.ac.uk/efo/EFO_0010142 GCST008654 Genome-wide genotyping array 667764 2019-09-13 31467194 Ganna A 2019-08-01 Science www.ncbi.nlm.nih.gov/pubmed/31467194 Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior. proportion of same-sex sexual behaviour among non-heterosexuals 7,675 European ancestry males NA Affymetrix, Illumina [NR] (imputed) 0 same-sex sexual behavior http://www.ebi.ac.uk/efo/EFO_0010142 GCST008655 Genome-wide genotyping array 7675 2019-09-13 31467194 Ganna A 2019-08-01 Science www.ncbi.nlm.nih.gov/pubmed/31467194 Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior. proportion of same-sex sexual behaviour among non-heterosexuals 5,838 European ancestry females NA Affymetrix, Illumina [NR] (imputed) 0 same-sex sexual behavior http://www.ebi.ac.uk/efo/EFO_0010142 GCST008656 Genome-wide genotyping array 5838 2019-09-13 31467194 Ganna A 2019-08-01 Science www.ncbi.nlm.nih.gov/pubmed/31467194 Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior. proportion of same-sex sexual behaviour among non-heterosexuals at least 7,675 European ancestry males, at least 5,838 European ancestry females NA Affymetrix, Illumina [NR] (imputed) 0 same-sex sexual behavior http://www.ebi.ac.uk/efo/EFO_0010142 GCST008657 Genome-wide genotyping array 13513 2019-09-13 31467194 Ganna A 2019-08-01 Science www.ncbi.nlm.nih.gov/pubmed/31467194 Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior. same-sex sexual behaviour 188,825 European ancestry males NA Affymetrix [NR] (imputed) 2 same-sex sexual behavior http://www.ebi.ac.uk/efo/EFO_0010142 GCST008649 Genome-wide genotyping array 188825 2019-09-13 31467194 Ganna A 2019-08-01 Science www.ncbi.nlm.nih.gov/pubmed/31467194 Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior. same-sex sexual behaviour 220,170 European ancestry females NA Affymetrix [NR] (imputed) 0 same-sex sexual behavior http://www.ebi.ac.uk/efo/EFO_0010142 GCST008650 Genome-wide genotyping array 220170 2019-09-13 31467194 Ganna A 2019-08-01 Science www.ncbi.nlm.nih.gov/pubmed/31467194 Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior. same-sex sexual behaviour 188,825 European ancestry males, 220,170 European ancestry females NA Affymetrix [NR] (imputed) 2 same-sex sexual behavior http://www.ebi.ac.uk/efo/EFO_0010142 GCST008651 Genome-wide genotyping array 408995 2019-02-20 30267110 Kwon YC 2018-09-28 Pediatr Cardiol www.ncbi.nlm.nih.gov/pubmed/30267110 Identification of the TIFAB Gene as a Susceptibility Locus for Coronary Artery Aneurysm in Patients with Kawasaki Disease. Coronary artery aneurysm in Kawasaki disease 33 cases, 215 controls 12 cases, 532 controls Illumina [~ 1000000] 1 coronary aneurysm http://www.ebi.ac.uk/efo/EFO_1000881 GCST007192 Genome-wide genotyping array 248 2019-07-10 30661054 Schafmayer C 2019-01-19 Gut www.ncbi.nlm.nih.gov/pubmed/30661054 Genome-wide association analysis of diverticular disease points towards neuromuscular, connective tissue and epithelial pathomechanisms. Diverticular disease 31,964 European ancestry cases, 419,135 European ancestry controls 4,611 European ancestry cases, 31,478 European ancestry controls Affymetrix [11977111] (imputed) 3 diverticular disease http://www.ebi.ac.uk/efo/EFO_0009959 GCST008105 Genome-wide genotyping array 451099 2019-02-20 30266950 Miyagawa T 2018-09-28 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30266950 A variant at 9q34.11 is associated with HLA-DQB1*06:02 negative essential hypersomnia. Hypersomnia (HLA-DQB1*06:02 negative) 119 Japanese ancestry cases, 1,582 Japanese ancestry controls 283 Japanese ancestry cases, 433 Japanese ancestry controls Affymetrix [476572] 1 hypersomnia http://www.ebi.ac.uk/efo/EFO_0005246 GCST007191 Genome-wide genotyping array 1701 2019-03-04 30595539 Wallace HJ 2018-12-27 Burns www.ncbi.nlm.nih.gov/pubmed/30595539 Genetic influence on scar height and pliability after burn injury in individuals of European ancestry: A prospective cohort study. Postburn scar height 665 European ancestry individuals NA Illumina [298150] 2 postburn hypertrophic scarring severity measurement http://www.ebi.ac.uk/efo/EFO_0007747 GCST007251 Genome-wide genotyping array 665 2019-03-04 30595539 Wallace HJ 2018-12-27 Burns www.ncbi.nlm.nih.gov/pubmed/30595539 Genetic influence on scar height and pliability after burn injury in individuals of European ancestry: A prospective cohort study. Postburn scar pliability 665 European ancestry individuals NA Illumina [298150] 4 postburn hypertrophic scarring severity measurement http://www.ebi.ac.uk/efo/EFO_0007747 GCST007252 Genome-wide genotyping array 665 2019-02-11 30217971 Ho KWD 2018-09-14 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/30217971 Genome-wide association study of seasonal affective disorder. Seasonality in depression 1,380 European ancestry cases, 2,464 European ancestry controls NA Affymetrix, Illumina [8153767] (imputed) 0 seasonality measurement http://www.ebi.ac.uk/efo/EFO_0006876 GCST007101 Genome-wide genotyping array 3844 2019-02-11 30217971 Ho KWD 2018-09-14 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/30217971 Genome-wide association study of seasonal affective disorder. Seasonality and depression 1,380 European ancestry cases, 2,937 European ancestry controls NA Affymetrix, Illumina [8153767] (imputed) 18 unipolar depression, seasonality measurement, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0006876, http://www.ebi.ac.uk/efo/EFO_0000289 GCST007102 Genome-wide genotyping array 4317 2021-01-26 32376654 Richardson TG 2020-05-06 BMJ www.ncbi.nlm.nih.gov/pubmed/32376654 Use of genetic variation to separate the effects of early and later life adiposity on disease risk: mendelian randomisation study. Body size at age 10 453,169 European ancestry individuals NA Affymetrix [12370749] 291 comparative body size at age 10, self-reported http://www.ebi.ac.uk/efo/EFO_0009819 GCST010989 Genome-wide genotyping array 453169 2021-01-26 32376654 Richardson TG 2020-05-06 BMJ www.ncbi.nlm.nih.gov/pubmed/32376654 Use of genetic variation to separate the effects of early and later life adiposity on disease risk: mendelian randomisation study. Adult body size 453,169 European ancestry individuals NA Affymetrix [12370749] 554 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST010988 Genome-wide genotyping array 453169 2021-05-19 32913026 Knol MJ 2020-09-10 Neurology www.ncbi.nlm.nih.gov/pubmed/32913026 Association of common genetic variants with brain microbleeds: A Genome-wide Association Study. Cerebral microbleeds 3,321 European ancestry cases, 42 Chinese ancestry cases, 75 Malay ancestry cases, 118 African American cases, 21,785 European ancestry controls, 88 Chinese ancestry controls, 129 Malay ancestry controls, 304 African American controls NA Affymetrix, Illumina [NR] (imputed) 4 cerebral microbleeds http://www.ebi.ac.uk/efo/EFO_0010059 GCST011707 Genome-wide genotyping array 25862 2021-05-19 32913026 Knol MJ 2020-09-10 Neurology www.ncbi.nlm.nih.gov/pubmed/32913026 Association of common genetic variants with brain microbleeds: A Genome-wide Association Study. Cerebral microbleeds (lobar) 2,035 European ancestry cases, 27 Chinese ancestry cases, 36 Malay ancestry cases, 81 African American cases, 21,785 European ancestry controls, 88 Chinese ancestry controls, 129 Malay ancestry controls, 304 African American controls NA Affymetrix, Illumina [NR] (imputed) 5 cerebral microbleeds http://www.ebi.ac.uk/efo/EFO_0010059 GCST011706 Genome-wide genotyping array 24485 2021-05-19 32913026 Knol MJ 2020-09-10 Neurology www.ncbi.nlm.nih.gov/pubmed/32913026 Association of common genetic variants with brain microbleeds: A Genome-wide Association Study. Cerebral microbleeds (mixed) 1,262 European ancestry cases, 31 African American cases, 21,785 European ancestry controls, 88 Chinese ancestry controls, 129 Malay ancestry controls, 304 African American controls NA Affymetrix, Illumina [NR] (imputed) 0 cerebral microbleeds http://www.ebi.ac.uk/efo/EFO_0010059 GCST011708 Genome-wide genotyping array 23599 2021-06-15 32914890 Li W 2020-09-11 Prostate www.ncbi.nlm.nih.gov/pubmed/32914890 Genome-wide association study identifies novel single nucleotide polymorphisms having age-specific effect on prostate-specific antigen levels. Prostate-specific antigen levels x age interaction 2,394 men 2,137 men Illumina [4428605] (imputed) 0 prostate specific antigen measurement, age at assessment http://www.ebi.ac.uk/efo/EFO_0004624, http://www.ebi.ac.uk/efo/EFO_0008007 GCST011906 Genome-wide genotyping array 2394 2021-01-06 32963334 Wei XT 2020-09-22 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32963334 Pleiotropic genomic variants at 17q21.31 associated with bone mineral density and body fat mass: a bivariate genome-wide association analysis. Bone mineral density (hip) 10,070 European ancestry individuals, 1,623 Han Chinese ancestry individuals, 843 African American individuals, 445 Hispanic individuals NA Affymetrix, Illumina [2374420] (imputed) 8 hip bone mineral density http://www.ebi.ac.uk/efo/EFO_0007702 GCST010921 Genome-wide genotyping array 12981 2021-01-06 32963334 Wei XT 2020-09-22 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32963334 Pleiotropic genomic variants at 17q21.31 associated with bone mineral density and body fat mass: a bivariate genome-wide association analysis. Body fat mass 10,070 European ancestry individuals, 1,623 Han Chinese ancestry individuals, 843 African American individuals, 445 Hispanic individuals NA Affymetrix, Illumina [2374420] (imputed) 3 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST010920 Genome-wide genotyping array 12981 2021-01-06 32963334 Wei XT 2020-09-22 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32963334 Pleiotropic genomic variants at 17q21.31 associated with bone mineral density and body fat mass: a bivariate genome-wide association analysis. Hip bone mineral density and total body fat mass (bivariate analysis) 10,070 European ancestry individuals, 1,623 Han Chinese ancestry individuals, 843 African American individuals, 445 Hispanic individuals NA Affymetrix, Illumina [2374420] (imputed) 14 hip bone mineral density, fat body mass http://www.ebi.ac.uk/efo/EFO_0007702, http://www.ebi.ac.uk/efo/EFO_0005409 GCST010922 Genome-wide genotyping array 12981 2019-04-05 29632382 Mahajan A 2018-04-09 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29632382 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. Type 2 diabetes 48,286 European ancestry cases, 250,671 European ancestry controls, 33,126 African American, East Asian, Hispanic/Latino or South Asian cases, 120,161 African American, East Asian, Hispanic/Latino or South Asian controls NA Affymetrix, Illumina [247470] 37 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST007515 Targeted genotyping array [Exome array] 452244 2019-04-05 29632382 Mahajan A 2018-04-09 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29632382 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. Type 2 diabetes up to 48,286 European ancestry cases, up to 250,671 European ancestry controls NA Affymetrix, Illumina [247470] 32 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST007517 Targeted genotyping array [Exome array] 298957 2019-04-05 29632382 Mahajan A 2018-04-09 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29632382 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. Type 2 diabetes (adjusted for BMI) 48,286 European ancestry cases, 250,671 European ancestry controls, 33,126 African American, East Asian, Hispanic/Latino or South Asian cases, 120,161 African American, East Asian, Hispanic/Latino or South Asian controls NA Affymetrix, Illumina [247470] 35 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST007516 Targeted genotyping array [Exome array] 452244 2019-04-05 29632382 Mahajan A 2018-04-09 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29632382 Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. Type 2 diabetes (adjusted for BMI) up to 48,286 European ancestry cases, up to 250,671 European ancestry controls NA Affymetrix, Illumina [247470] 35 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST007518 Targeted genotyping array [Exome array] 298957 2018-06-29 29650774 Rotroff DM 2018-04-12 Diabetes www.ncbi.nlm.nih.gov/pubmed/29650774 Genetic Variants in CPA6 and PRPF31 are Associated with Variation in Response to Metformin in Individuals with Type 2 Diabetes. Change in HbA1c levels in response to metformin treatment in type 2 diabetes 845 European ancestry individuals, 222 African American individuals, 245 individuals 6,963 European ancestry individuals, 1,015 African American individuals, 4,520 individuals Affymetrix, Illumina [26000000] (imputed) 1 HbA1c measurement, response to metformin http://www.ebi.ac.uk/efo/EFO_0004541, http://purl.obolibrary.org/obo/GO_1901558 GCST005753 Genome-wide genotyping array 1312 2021-04-16 33608531 Wu Y 2021-02-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33608531 GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression. Peptic ulcer disease 16,666 European ancestry cases, 439,661 European ancestry controls NA NR [8546065] (imputed) 8 peptic ulcer disease http://purl.obolibrary.org/obo/MONDO_0004247 GCST011504 Genome-wide genotyping array 456327 2021-04-16 33608531 Wu Y 2021-02-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33608531 GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression. Gastroesophageal reflux disease 54,854 European ancestry cases, 401,473 European ancestry controls NA NR [8546065] (imputed) 6 gastroesophageal reflux disease http://www.ebi.ac.uk/efo/EFO_0003948 GCST011503 Genome-wide genotyping array 456327 2021-04-16 33608531 Wu Y 2021-02-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33608531 GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression. Irritable bowel syndrome 28,518 European ancestry cases, 426,803 European ancestry controls NA NR [8546065] (imputed) 2 irritable bowel syndrome http://www.ebi.ac.uk/efo/EFO_0000555 GCST011502 Genome-wide genotyping array 455321 2021-04-16 33608531 Wu Y 2021-02-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33608531 GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression. Inflammatory bowel disease 7,045 European ancestry cases, 449,282 European ancestry controls NA NR [8546065] (imputed) 31 inflammatory bowel disease http://www.ebi.ac.uk/efo/EFO_0003767 GCST011501 Genome-wide genotyping array 456327 2021-04-16 33608531 Wu Y 2021-02-19 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33608531 GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression. Gastroesophageal reflux disease, peptic ulcer disease and/or corresponding medications and treatment 90,175 European ancestry cases, 366,152 European ancestry controls NA NR [8546065] (imputed) 19 peptic ulcer disease, Peptic ulcer and gastro-oesophageal reflux disease (GORD) drug use measurement, gastroesophageal reflux disease http://purl.obolibrary.org/obo/MONDO_0004247, http://www.ebi.ac.uk/efo/EFO_0009923, http://www.ebi.ac.uk/efo/EFO_0003948 GCST011500 Genome-wide genotyping array 456327 2021-02-26 33477890 Voorhies K 2021-01-19 J Pers Med www.ncbi.nlm.nih.gov/pubmed/33477890 Age by Single Nucleotide Polymorphism Interactions on Bronchodilator Response in Asthmatics. Bronchodilator response x age interaction in asthma 892 European ancestry individuals 559 European ancestry individuals NR [5638778] (imputed) 0 response to bronchodilator, age at assessment http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0008007 GCST011164 Genome-wide genotyping array 892 2021-05-26 32830257 Castellucci LC 2020-08-23 Clin Infect Dis www.ncbi.nlm.nih.gov/pubmed/32830257 A Genome-Wide Association Study Identifies SERPINB10, CRLF3, STX7, LAMP3, IFNG-AS1 and KRT80 As Risk Loci Contributing to Cutaneous Leishmaniasis In Brazil. Cutaneous leishmaniasis 2,066 Hispanic/Latino cases, 2,046 Hispanic/Latino controls NR Illumina [4498586] (imputed) 14 cutaneous Leishmaniasis http://www.ebi.ac.uk/efo/EFO_0005046 GCST011739 Genome-wide genotyping array 4112 2019-06-21 31081985 Stein MB 2019-05-13 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/31081985 Genome-wide analyses of psychological resilience in U.S. Army soldiers. Psychological resilience (outcome-based) in high deployment stress exposure 581 European ancestry cases and controls NA Illumina [at least 664457] (imputed) 2 psychological resilience measurement http://www.ebi.ac.uk/efo/EFO_0009945 GCST007945 Genome-wide genotyping array 581 2019-06-21 31081985 Stein MB 2019-05-13 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/31081985 Genome-wide analyses of psychological resilience in U.S. Army soldiers. Psychological resilience (self-assessed) 11,473 European ancestry individuals NA Illumina [at least 360704] (imputed) 2 psychological resilience measurement http://www.ebi.ac.uk/efo/EFO_0009945 GCST007946 Genome-wide genotyping array 11473 2019-06-21 31081985 Stein MB 2019-05-13 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/31081985 Genome-wide analyses of psychological resilience in U.S. Army soldiers. Psychological resilience (outcome-based) 1,558 European ancestry resilient cases, 381 European ancestry controls with post-deployment mental disorder NA Illumina [at least 664457] (imputed) 5 psychological resilience measurement http://www.ebi.ac.uk/efo/EFO_0009945 GCST007947 Genome-wide genotyping array 1939 2021-04-07 32841424 Herrera-Luis E 2020-08-25 Pediatr Allergy Immunol www.ncbi.nlm.nih.gov/pubmed/32841424 Genome-wide association study reveals a novel locus for asthma with severe exacerbations in diverse populations. Asthma with severe exacerbations 1,283 Latino cases, 2,027 Latino controls 448 African American cases, 595 African American controls Affymetrix [9737707] (imputed) 21 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST011457 Genome-wide genotyping array 3310 2021-02-16 32077919 Antikainen AAV 2020-02-20 Cardiovasc Res www.ncbi.nlm.nih.gov/pubmed/32077919 Genome-wide association study on coronary artery disease in type 1 diabetes suggests beta-defensin 127 as a risk locus. Coronary artery disease in type 1 diabetes 941 European ancestry cases, 3,928 European ancestry controls 434 cases, 3,123 controls Illumina [8744746] (imputed) 9 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST011116 Genome-wide genotyping array 4869 2018-12-11 30248107 Wu S 2018-09-24 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30248107 Genome-wide association studies and CRISPR/Cas9-mediated gene editing identify regulatory variants influencing eyebrow thickness in humans. Eyebrow thickness 2,961 Han Chinese ancestry individuals, 721 Uyghur ancestry individuals, 2,301 Latin American ancestry individuals 4,411 Dutch ancestry individuals Illumina [up to 7224952] (imputed) 4 facial hair thickness measurement http://www.ebi.ac.uk/efo/EFO_0007823 GCST006706 Genome-wide genotyping array 5983 2019-02-06 30251476 Lopez-Mejias R 2018-09-24 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/30251476 A genome-wide association study identifies a 3'UTR genetic variant of RARB associated with carotid intima-media thickness in rheumatoid arthritis. Carotid intima media thickness in rheumatoid arthritis 1,355 Spanish ancestry individuals NA Illumina [63089444] (imputed) 3 carotid artery intima media thickness http://www.ebi.ac.uk/efo/EFO_0007117 GCST007040 Genome-wide genotyping array 1355 2019-02-06 30251476 Lopez-Mejias R 2018-09-24 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/30251476 A genome-wide association study identifies a 3'UTR genetic variant of RARB associated with carotid intima-media thickness in rheumatoid arthritis. Cardiovascular event in rheumatoid arthritis 467 Spanish ancestry patients, 2,522 Spanish ancestry controls NA Illumina [63089444] (imputed) 1 cardiovascular disease http://www.ebi.ac.uk/efo/EFO_0000319 GCST007041 Genome-wide genotyping array 2989 2019-02-08 30251476 Lopez-Mejias R 2018-09-24 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/30251476 A genome-wide association study identifies a 3'UTR genetic variant of RARB associated with carotid intima-media thickness in rheumatoid arthritis. Ischemic heart disease in rheumatoid arthritis 224 Spanish ancestry patients, 2,765 Spanish ancestry controls NA Illumina [63089444] (imputed) 3 ischemic cardiomyopathy http://www.ebi.ac.uk/efo/EFO_0001425 GCST007088 Genome-wide genotyping array 2989 2019-03-27 30251476 Lopez-Mejias R 2018-09-24 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/30251476 A genome-wide association study identifies a 3'UTR genetic variant of RARB associated with carotid intima-media thickness in rheumatoid arthritis. Carotid plaques in rheumatoid arthritis 1,355 Spanish ancestry individuals NA Illumina [63089444] (imputed) 4 carotid atherosclerosis http://www.ebi.ac.uk/efo/EFO_0009783 GCST007425 Genome-wide genotyping array 1355 2018-11-05 30247649 Gonzalez-Serna D 2018-09-21 Rheumatology (Oxford) www.ncbi.nlm.nih.gov/pubmed/30247649 Analysis of the genetic component of systemic sclerosis in Iranian and Turkish populations through a genome-wide association study. Systemic sclerosis 764 Middle Eastern ancestry cases, 1,343 Middle Eastern ancestry controls NA Illumina [5698748] (imputed) 11 systemic scleroderma http://www.ebi.ac.uk/efo/EFO_0000717 GCST006493 Genome-wide genotyping array 2107 2021-07-27 33495439 Demontis D 2021-01-25 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33495439 Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder. Disruptive behavior disorder in attention deficit hyperactivity disorder 1,959 European ancestry cases, 13,539 European ancestry controls NA Illumina [NR] 0 conduct disorder, Oppositional defiant disorder http://www.ebi.ac.uk/efo/EFO_0004216, http://purl.obolibrary.org/obo/HP_0010865 GCST012097 Genome-wide genotyping array 15498 2021-07-27 33495439 Demontis D 2021-01-25 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33495439 Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder. Attention deficit hyperactivity disorder 13,583 European ancestry cases, 22,314 European ancestry controls NA Illumina [NR] 1 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST012096 Genome-wide genotyping array 35897 2021-07-27 33495439 Demontis D 2021-01-25 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33495439 Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder. Disruptive behavior disorder and attention deficit hyperactivity disorder 3,802 European ancestry cases, 31,305 European ancestry controls, 406 Han Chinese ancestry cases, 917 Han Chinese ancestry controls NA Affymetrix, Illumina, Perlegen [8285688] (imputed) 3 attention deficit hyperactivity disorder, conduct disorder, Oppositional defiant disorder http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0004216, http://purl.obolibrary.org/obo/HP_0010865 GCST012098 Genome-wide genotyping array 36430 2021-07-28 33491795 Timmer T 2021-01-25 Vox Sang www.ncbi.nlm.nih.gov/pubmed/33491795 Genetic determinants of ferritin, haemoglobin levels and haemoglobin trajectories: results from Donor InSight. Hemoglobin levels 2,649 European ancestry individuals NA Affymetrix [7435577] (imputed) 20 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST012146 Genome-wide genotyping array 2649 2021-07-28 33491795 Timmer T 2021-01-25 Vox Sang www.ncbi.nlm.nih.gov/pubmed/33491795 Genetic determinants of ferritin, haemoglobin levels and haemoglobin trajectories: results from Donor InSight. Ferritin levels 2,649 European ancestry individuals NA Affymetrix [7435577] (imputed) 24 ferritin measurement http://www.ebi.ac.uk/efo/EFO_0004459 GCST012145 Genome-wide genotyping array 2649 2021-07-28 33491795 Timmer T 2021-01-25 Vox Sang www.ncbi.nlm.nih.gov/pubmed/33491795 Genetic determinants of ferritin, haemoglobin levels and haemoglobin trajectories: results from Donor InSight. Declining hemoglobin trajectory in blood donors 1,044 European ancestry cases, 783 European ancestry controls NA Affymetrix [7435577] (imputed) 12 hemoglobin change measurement http://www.ebi.ac.uk/efo/EFO_0600027 GCST012147 Genome-wide genotyping array 1827 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Dilated cardiomyopathy 5,521 cases, 397,323 controls NA Affymetrix, Illumina [up to 7736182] (imputed) 6 dilated cardiomyopathy http://www.ebi.ac.uk/efo/EFO_0000407 GCST011210 Genome-wide genotyping array 402844 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Left ventricular ejection fraction 19,260 European ancestry individuals NA Affymetrix [~ 9500000] (imputed) 5 left ventricular ejection fraction measurement http://www.ebi.ac.uk/efo/EFO_0008373 GCST011209 Genome-wide genotyping array 19260 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Left ventricular mass to end-diastolic volume ratio 19,260 European ancestry individuals NA Affymetrix [~ 9500000] (imputed) 8 Left ventricular mass to end-diastolic volume ratio http://www.ebi.ac.uk/efo/EFO_0010556 GCST011208 Genome-wide genotyping array 19260 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Left ventricular mass 19,260 European ancestry individuals NA Affymetrix [~ 9500000] (imputed) 4 left ventricular mass http://www.ebi.ac.uk/efo/EFO_0009289 GCST011207 Genome-wide genotyping array 19260 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Left ventricular end-diastolic volume 19,260 European ancestry individuals NA Affymetrix [~ 9500000] (imputed) 4 left ventricular diastolic function measurement http://www.ebi.ac.uk/efo/EFO_0008204 GCST011206 Genome-wide genotyping array 19260 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Left ventricular end-systolic volume 19,260 European ancestry individuals NA Affymetrix [~ 9500000] (imputed) 9 left ventricular systolic function measurement http://www.ebi.ac.uk/efo/EFO_0008206 GCST011198 Genome-wide genotyping array 19260 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Left ventricular global circumferential strain 19,260 European ancestry individuals NA Affymetrix [~ 9500000] (imputed) 10 heart function measurement http://www.ebi.ac.uk/efo/EFO_0004311 GCST011217 Genome-wide genotyping array 19260 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Left ventricular global radial strain 19,260 European ancestry individuals NA Affymetrix [~ 9500000] (imputed) 7 heart function measurement http://www.ebi.ac.uk/efo/EFO_0004311 GCST011216 Genome-wide genotyping array 19260 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Left ventricular global longitudinal strain 19,260 European ancestry individuals NA Affymetrix [~ 9500000] (imputed) 1 heart function measurement http://www.ebi.ac.uk/efo/EFO_0004311 GCST011215 Genome-wide genotyping array 19260 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Left ventricle wall thickness 19,260 European ancestry individuals NA Affymetrix [~ 9500000] (imputed) 9 left ventricular structural measurement http://www.ebi.ac.uk/efo/EFO_0008205 GCST011214 Genome-wide genotyping array 19260 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Hypertrophic cardiomyopathy (MTAG) 1,733 European ancestry cases, 6,628 European ancestry controls NA Illumina [6530233] (imputed) 16 hypertrophic cardiomyopathy http://www.ebi.ac.uk/efo/EFO_0000538 GCST011205 Genome-wide genotyping array 8361 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Dilated cardiomyopathy (MTAG) 5,521 cases, 397,323 controls NA Affymetrix, Illumina [up to 7736182] (imputed) 13 dilated cardiomyopathy http://www.ebi.ac.uk/efo/EFO_0000407 GCST011202 Genome-wide genotyping array 402844 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Left ventricular ejection fraction (MTAG) 19,260 European ancestry individuals NA Affymetrix [~ 9500000] (imputed) 1 left ventricular ejection fraction measurement http://www.ebi.ac.uk/efo/EFO_0008373 GCST011204 Genome-wide genotyping array 19260 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Left ventricular mass to end-diastolic volume ratio (MTAG) 19,260 European ancestry individuals NA Affymetrix [~ 9500000] (imputed) 1 Left ventricular mass to end-diastolic volume ratio http://www.ebi.ac.uk/efo/EFO_0010556 GCST011213 Genome-wide genotyping array 19260 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Left ventricular mass (MTAG) 19,260 European ancestry individuals NA Affymetrix [~ 9500000] (imputed) 1 left ventricular mass http://www.ebi.ac.uk/efo/EFO_0009289 GCST011212 Genome-wide genotyping array 19260 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Left ventricular end-diastolic volume (MTAG) 19,260 European ancestry individuals NA Affymetrix [~ 9500000] (imputed) 3 left ventricular diastolic function measurement http://www.ebi.ac.uk/efo/EFO_0008204 GCST011203 Genome-wide genotyping array 19260 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Left ventricular end-systolic volume (MTAG) 19,260 European ancestry individuals NA Affymetrix [~ 9500000] (imputed) 3 left ventricular systolic function measurement http://www.ebi.ac.uk/efo/EFO_0008206 GCST011197 Genome-wide genotyping array 19260 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Left ventricular global circumferential strain (MTAG) 19,260 European ancestry individuals NA Affymetrix [~ 9500000] (imputed) 1 heart function measurement http://www.ebi.ac.uk/efo/EFO_0004311 GCST011201 Genome-wide genotyping array 19260 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Left ventricular global radial strain (MTAG) 19,260 European ancestry individuals NA Affymetrix [~ 9500000] (imputed) 1 heart function measurement http://www.ebi.ac.uk/efo/EFO_0004311 GCST011200 Genome-wide genotyping array 19260 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Left ventricular global longitudinal strain (MTAG) 19,260 European ancestry individuals NA Affymetrix [~ 9500000] (imputed) 1 heart function measurement http://www.ebi.ac.uk/efo/EFO_0004311 GCST011199 Genome-wide genotyping array 19260 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Left ventricle wall thickness (MTAG) 19,260 European ancestry individuals NA Affymetrix [~ 9500000] (imputed) 0 heart function measurement http://www.ebi.ac.uk/efo/EFO_0004311 GCST011196 Genome-wide genotyping array 19260 2021-03-05 33495596 Tadros R 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495596 Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Hypertrophic cardiomyopathy 1,733 European ancestry cases, 6,628 European ancestry controls 2,694 European ancestry cases, 47,486 European ancestry controls Illumina [6530233] (imputed) 15 hypertrophic cardiomyopathy http://www.ebi.ac.uk/efo/EFO_0000538 GCST011211 Genome-wide genotyping array 8361 2019-03-15 30413934 Broce IJ 2018-11-09 Acta Neuropathol www.ncbi.nlm.nih.gov/pubmed/30413934 Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease. Alzheimer's disease or cardiovascular risk factors (pleiotropy) 17,008 European ancestry Alzheimer's disease cases, 48,286 European ancestry type 2 diabetes cases, 17,283 European ancestry coronary artery disease cases, 425,739 European ancestry controls, 923,864 European ancestry individuals NA NR [up to 27375637] (imputed) 0 Alzheimer's disease, total cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, waist-hip ratio, type II diabetes mellitus, body mass index, high density lipoprotein cholesterol measurement, coronary artery disease http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0004611, http://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0001360, http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004612, http://www.ebi.ac.uk/efo/EFO_0001645 GCST007303 Genome-wide genotyping array 1432182 2021-03-22 32961594 Neuvonen M 2020-09-22 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/32961594 Identification of Glycochenodeoxycholate 3-O-Glucuronide and Glycodeoxycholate 3-O-Glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers. Fasting plasma glycodeoxycholate 3-O-glucuronide concentration 356 Finnish ancestry individuals NA Illumina [NR] 1 glycodeoxycholate 3-O-glucuronide measurement http://www.ebi.ac.uk/efo/EFO_0011010 GCST011372 Genome-wide genotyping array 356 2021-03-22 32961594 Neuvonen M 2020-09-22 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/32961594 Identification of Glycochenodeoxycholate 3-O-Glucuronide and Glycodeoxycholate 3-O-Glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers. Fasting plasma glycochenodeoxycholate 3-O-glucuronide concentration 356 Finnish ancestry individuals NA Illumina [NR] 1 glycochenodeoxycholate 3-O-glucuronide measurement http://www.ebi.ac.uk/efo/EFO_0011009 GCST011373 Genome-wide genotyping array 356 2019-05-07 30850646 Tziotzios C 2019-03-08 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30850646 Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02. Frontal fibrosing alopecia 1,016 European ancestry cases, 4,145 European ancestry controls NA Illumina [~ 8000000] (imputed) 37 frontal fibrosing alopecia http://www.ebi.ac.uk/efo/EFO_0009855 GCST007713 Genome-wide genotyping array 5161 2019-04-30 30843173 Popovic M 2019-03-07 J Endocrinol Invest www.ncbi.nlm.nih.gov/pubmed/30843173 Genome-wide meta-analysis identifies novel loci associated with free triiodothyronine and thyroid-stimulating hormone. Triiodothyronine levels 629 Croatian individuals, 510 Korculan (founder/genetic isolate) individuals, 590 Vis (founder/genetic isolate) individuals NA Illumina [7411206] (imputed) 3 triiodothyronine measurement http://www.ebi.ac.uk/efo/EFO_0008392 GCST007683 Genome-wide genotyping array 1729 2019-04-30 30843173 Popovic M 2019-03-07 J Endocrinol Invest www.ncbi.nlm.nih.gov/pubmed/30843173 Genome-wide meta-analysis identifies novel loci associated with free triiodothyronine and thyroid-stimulating hormone. Thyroxine levels 596 Croatian individuals, 510 Korculan (founder/genetic isolate) individuals, 609 Vis (founder/genetic isolate) individuals NA Illumina [7411206] (imputed) 4 thyroxine measurement http://www.ebi.ac.uk/efo/EFO_0005130 GCST007682 Genome-wide genotyping array 1715 2019-04-30 30843173 Popovic M 2019-03-07 J Endocrinol Invest www.ncbi.nlm.nih.gov/pubmed/30843173 Genome-wide meta-analysis identifies novel loci associated with free triiodothyronine and thyroid-stimulating hormone. Thyroid stimulating hormone levels 626 Croatian individuals, 509 Korculan (founder/genetic isolate) individuals, 596 Vis (founder/genetic isolate) individuals NA Illumina [7411206] (imputed) 4 thyroid stimulating hormone measurement http://www.ebi.ac.uk/efo/EFO_0004748 GCST007681 Genome-wide genotyping array 1731 2019-04-30 30843173 Popovic M 2019-03-07 J Endocrinol Invest www.ncbi.nlm.nih.gov/pubmed/30843173 Genome-wide meta-analysis identifies novel loci associated with free triiodothyronine and thyroid-stimulating hormone. Triiodothyronine levels and thyroxine levels Up to 1,729 Croatian, Korculan (founder/genetic isolate) and Vis (founder/genetic isolate) individuals NA Illumina [7411206] (imputed) 11 thyroxine measurement, triiodothyronine measurement http://www.ebi.ac.uk/efo/EFO_0005130, http://www.ebi.ac.uk/efo/EFO_0008392 GCST007680 Genome-wide genotyping array 1729 2019-04-12 30846698 Dashti HS 2019-03-07 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30846698 Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates. Sleep duration (short sleep) 106,192 European ancestry cases, 305,742 European ancestry controls 47,180 adults, 10,554 children or adolescents NR [14661600] (imputed) 27 sleep duration http://www.ebi.ac.uk/efo/EFO_0005271 GCST007559 Genome-wide genotyping array 411934 2019-04-12 30846698 Dashti HS 2019-03-07 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30846698 Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates. Sleep duration (long sleep) 34,184 European ancestry cases, 305,742 European ancestry controls 47,180 adults, 10,554 children or adolescents Affymetrix [14661600] (imputed) 8 sleep duration http://www.ebi.ac.uk/efo/EFO_0005271 GCST007560 Genome-wide genotyping array 339926 2019-04-12 30846698 Dashti HS 2019-03-07 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30846698 Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates. Sleep duration 446,118 European ancestry individuals 47,180 adults, 10,554 children or adolescents Affymetrix [14661600] (imputed) 72 sleep duration http://www.ebi.ac.uk/efo/EFO_0005271 GCST007561 Genome-wide genotyping array 446118 2019-06-26 28714974 Klarin D 2017-07-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/28714974 Genetic analysis in UK Biobank links insulin resistance and transendothelial migration pathways to coronary artery disease. Coronary artery disease 4,831 European ancestry cases, 115,455 European ancestry controls up to 60,801 European and unknown ancestry cases, up to 123,504 European and unknown ancestry controls Affymetrix [9061845] (imputed) 20 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST007990 Genome-wide genotyping array 120286 2019-04-16 30833571 Wiberg A 2019-03-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30833571 A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome. Carpal tunnel syndrome 12,312 European ancestry cases, 389,344 European ancestry controls NA Affymetrix [84000000] (imputed) 16 carpal tunnel syndrome http://www.ebi.ac.uk/efo/EFO_0004143 GCST007581 Genome-wide genotyping array 401656 2018-10-19 30220432 Haas ME 2018-09-06 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30220432 Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure. Urinary albumin excretion (no hypertensive medication) 302,687 European ancestry individuals without hypertensive medication NA Affymetrix [11709857] (imputed) 23 albuminuria http://www.ebi.ac.uk/efo/EFO_0004285 GCST006463 Genome-wide genotyping array 302687 2018-11-19 30220432 Haas ME 2018-09-06 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30220432 Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure. Urinary albumin excretion 382,500 European ancestry individuals NA Affymetrix [11709857] (imputed) 46 albuminuria http://www.ebi.ac.uk/efo/EFO_0004285 GCST006586 Genome-wide genotyping array 382500 2018-06-27 29659830 Warrington NM 2018-04-12 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/29659830 Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero. Digit length ratio (right hand) 12,636 European ancestry individuals NA Illumina [8400000] (imputed) 11 digit length ratio http://www.ebi.ac.uk/efo/EFO_0004841 GCST005748 Genome-wide genotyping array 12636 2018-06-27 29659830 Warrington NM 2018-04-12 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/29659830 Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero. Digit length ratio 12,586 European ancestry individuals NA Illumina [8400000] (imputed) 12 digit length ratio http://www.ebi.ac.uk/efo/EFO_0004841 GCST005750 Genome-wide genotyping array 12586 2018-06-27 29659830 Warrington NM 2018-04-12 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/29659830 Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero. Digit length ratio (left hand) 14,382 European ancestry individuals, 1,279 non-European ancestry individuals NA Illumina [8400000] (imputed) 24 digit length ratio http://www.ebi.ac.uk/efo/EFO_0004841 GCST005749 Genome-wide genotyping array 15661 2019-03-14 30263045 Blackburn NB 2018-09-17 BMC Proc www.ncbi.nlm.nih.gov/pubmed/30263045 Heritability and genetic associations of triglyceride and HDL-C levels using pedigree-based and empirical kinships. High density lipoprotein cholesterol levels 817 individuals NA NR [718407] 1 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST007301 Genome-wide genotyping array 817 2019-03-14 30263045 Blackburn NB 2018-09-17 BMC Proc www.ncbi.nlm.nih.gov/pubmed/30263045 Heritability and genetic associations of triglyceride and HDL-C levels using pedigree-based and empirical kinships. Response to fenofibrate (HDL cholesterol levels) 817 individuals NA NR [718407] 1 high density lipoprotein cholesterol measurement, response to fenofibrate http://www.ebi.ac.uk/efo/EFO_0004612, http://purl.obolibrary.org/obo/GO_1901557 GCST007300 Genome-wide genotyping array 817 2019-03-14 30263045 Blackburn NB 2018-09-17 BMC Proc www.ncbi.nlm.nih.gov/pubmed/30263045 Heritability and genetic associations of triglyceride and HDL-C levels using pedigree-based and empirical kinships. Triglyceride levels 817 individuals NA NR [718407] 0 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST007299 Genome-wide genotyping array 817 2019-03-14 30263045 Blackburn NB 2018-09-17 BMC Proc www.ncbi.nlm.nih.gov/pubmed/30263045 Heritability and genetic associations of triglyceride and HDL-C levels using pedigree-based and empirical kinships. Response to fenofibrate (triglyceride levels) 774 individuals NA NR [718407] 0 triglyceride measurement, response to fenofibrate http://www.ebi.ac.uk/efo/EFO_0004530, http://purl.obolibrary.org/obo/GO_1901557 GCST007298 Genome-wide genotyping array 774 2018-07-09 29691431 Tikkanen E 2018-04-24 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29691431 Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank. Hand grip strength 334,825 British ancestry individuals NA Affymetrix [15275733] (imputed) 139 grip strength measurement http://www.ebi.ac.uk/efo/EFO_0006941 GCST005830 Genome-wide genotyping array 334825 2018-07-09 29691431 Tikkanen E 2018-04-24 Sci Rep www.ncbi.nlm.nih.gov/pubmed/29691431 Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank. Hand grip strength 223,215 British ancestry individuals 111,610 British ancestry individuals Affymetrix [15275733] (imputed) 27 grip strength measurement http://www.ebi.ac.uk/efo/EFO_0006941 GCST005829 Genome-wide genotyping array 223215 2019-08-05 31043758 Warrington NM 2019-05-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31043758 Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. Offspring birth weight 210,267 European ancestry individuals, 19,802 individuals NR Affymetrix, Illumina [14869762] (imputed) 133 birth weight, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0004344, http://www.ebi.ac.uk/efo/EFO_0005939 GCST008363 Genome-wide genotyping array 230069 2019-08-05 31043758 Warrington NM 2019-05-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/31043758 Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. Birth weight 298,142 European ancestry individuals, 6,635 African American individuals, 1,449 Filipino individuals, 420 Turkish individuals, 365 Moroccan individuals, 395 Surinamese individuals, 1,052 Afro-Caribbean individuals, 612 Hispanic individuals, 1,180 Thai individuals, 840 Chinese ancestry individuals, 10,133 individuals NR Affymetrix, Illumina [15144367] (imputed) 225 birth weight http://www.ebi.ac.uk/efo/EFO_0004344 GCST008362 Genome-wide genotyping array 321223 2018-09-17 30034349 Lin E 2018-07-06 Front Psychiatry www.ncbi.nlm.nih.gov/pubmed/30034349 A Deep Learning Approach for Predicting Antidepressant Response in Major Depression Using Clinical and Genetic Biomarkers. Response to selective serotonin reuptake inhibitors in depression 257 Taiwanese ancestry responders, 164 Taiwanese ancestry non-responders NA Illumina [4241701] (imputed) 3 response to selective serotonin reuptake inhibitor http://www.ebi.ac.uk/efo/EFO_0005658 GCST006267 Genome-wide genotyping array 421 2018-09-17 30034349 Lin E 2018-07-06 Front Psychiatry www.ncbi.nlm.nih.gov/pubmed/30034349 A Deep Learning Approach for Predicting Antidepressant Response in Major Depression Using Clinical and Genetic Biomarkers. Remission after SSRI treatment in major depression 139 Taiwanese ancestry remitted cases, 282 Taiwanese ancestry non-remitted cases NA Illumina [4241701] (imputed) 1 response to selective serotonin reuptake inhibitor http://www.ebi.ac.uk/efo/EFO_0005658 GCST006266 Genome-wide genotyping array 421 2019-07-02 30201328 Gusareva ES 2018-08-09 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/30201328 Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease. Alzheimer's disease (SNP x SNP interaction) 788 male cases, 1,455 female cases, 2,362 male controls, 3,655 female controls 3,836 male cases, 6,244 female cases, 8,618 male controls, 11,624 female controls Illumina [312064] 2 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST008056 Genome-wide genotyping array 8260 2018-10-15 30104567 Ji X 2018-08-13 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30104567 Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk. Lung cancer in ever smokers 4,628 European ancestry cases, 4,041 European ancestry controls 16,341 European ancestry cases, 9,930 European ancestry controls Illumina [20734083] (imputed) 1 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST006400 Genome-wide genotyping array 8669 2018-10-15 30104567 Ji X 2018-08-13 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30104567 Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk. Lung cancer (SNP x SNP interaction) 4,918 European ancestry cases, 5,555 European ancestry controls NA Illumina [2482200] (imputed) 25 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST006398 Genome-wide genotyping array 10473 2018-10-15 30104567 Ji X 2018-08-13 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30104567 Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk. Lung cancer 4,918 European ancestry cases, 5,555 European ancestry controls 18,439 European ancestry cases, 14,026 European ancestry controls Illumina [20734083] (imputed) 1 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST006399 Genome-wide genotyping array 10473 2018-11-05 30217807 Robinson-Cohen C 2018-09-14 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/30217807 Genetic Variants Associated with Circulating Fibroblast Growth Factor 23. Circulating fibroblast growth factor 23 levels 16,624 European ancestry individuals 4,443 African ancestry individuals Affymetrix, Illumina [NR] (imputed) 19 fibroblast growth factor 23 measurement http://www.ebi.ac.uk/efo/EFO_0009381 GCST006491 Genome-wide genotyping array 16624 2019-03-20 30206298 Spear ML 2018-09-12 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/30206298 A genome-wide association and admixture mapping study of bronchodilator drug response in African Americans with asthma. Bronchodilator response in asthma 949 African American cases, 1,830 Latino cases 1,615 African American cases, 416 Latino cases Affymetrix [up to 9605653] (imputed) 0 response to bronchodilator http://purl.obolibrary.org/obo/GO_0097366 GCST007360 Genome-wide genotyping array 2779 2019-02-13 30284222 Brcic L 2018-10-03 J Endocrinol Invest www.ncbi.nlm.nih.gov/pubmed/30284222 Genome-wide association analysis suggests novel loci for Hashimoto's thyroiditis. Hashimoto thyroiditis 405 Croatian ancestry cases, 433 Croatian ancestry controls 303 Croatian ancestry cases, 302 Croatian ancestry controls Illumina [8621046] (imputed) 1 Hashimoto's thyroiditis http://www.ebi.ac.uk/efo/EFO_0003779 GCST007138 Genome-wide genotyping array 838 2018-12-11 30281099 Fadista J 2018-10-02 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30281099 Genome-wide meta-analysis identifies BARX1 and EML4-MTA3 as new loci associated with infantile hypertrophic pyloric stenosis. Infantile hypertrophic pyloric stenosis 1,395 Danish ancestry cases, 4,438 Danish ancestry controls 1,794 European ancestry cases, 633 Hispanic ancestry cases, 1,875 European ancestry controls, 633 Hispanic ancestry controls Illumina [6576307] (imputed) 13 infantile hypertrophic pyloric stenosis http://www.ebi.ac.uk/efo/EFO_0004707 GCST006705 Genome-wide genotyping array 5833 2018-12-11 30281874 Tanikawa C 2018-10-03 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/30281874 A GWAS identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21. Gastric cancer 6,171 Japanese ancestry cases, 27,178 Japanese ancestry controls 5,336 Japanese ancestry cases, 11,726 Japanese ancestry controls Illumina [6573681] (imputed) 6 gastric carcinoma http://www.ebi.ac.uk/efo/EFO_0000178 GCST006707 Genome-wide genotyping array 33349 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Total hippocampal volume 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 8 hippocampal volume http://www.ebi.ac.uk/efo/EFO_0005035 GCST006871 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Presubiculum volume (corrected for total hippocampal volume) 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 1 presubiculum volume http://www.ebi.ac.uk/efo/EFO_0009400 GCST006872 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Subiculum volume (corrected for total hippocampal volume) 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 1 subiculum volume http://www.ebi.ac.uk/efo/EFO_0009399 GCST006873 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Hippocampal subfield CA1 volume (corrected for total hippocampal volume) 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 2 hippocampal CA1 volume http://www.ebi.ac.uk/efo/EFO_0009394 GCST006874 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Hippocampal subfield CA3 volume (corrected for total hippocampal volume) 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 0 hippocampal CA3 volume http://www.ebi.ac.uk/efo/EFO_0009395 GCST006875 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Hippocampal subfield CA4 volume (corrected for total hippocampal volume) 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 0 hippocampal CA4 volume http://www.ebi.ac.uk/efo/EFO_0009396 GCST006876 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Dentate gyrus granule cell layer volume (corrected for total hippocampal volume) 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 1 granule cell layer dentate gyrus volume http://www.ebi.ac.uk/efo/EFO_0009403 GCST006877 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Dentate gyrus molecular layer volume (corrected for total hippocampal volume) 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 1 hippocampus molecular layer volume http://www.ebi.ac.uk/efo/EFO_0009397 GCST006878 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Hippocampal fissure volume (corrected for total hippocampal volume) 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 0 hippocampal fissure volume http://www.ebi.ac.uk/efo/EFO_0009404 GCST006880 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Hippocampal tail volume (corrected for total hippocampal volume) 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 7 hippocampal tail volume http://www.ebi.ac.uk/efo/EFO_0009398 GCST006881 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Fimbria volume (corrected for total hippocampal volume) 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 0 hippocampus fimbria volume http://www.ebi.ac.uk/efo/EFO_0009402 GCST006882 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. HATA volume (corrected for total hippocampal volume) 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 0 hippocampal amigdala transition area volume http://www.ebi.ac.uk/efo/EFO_0009401 GCST006883 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Parasubiculum volume (corrected for total hippocampal volume) 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 0 parasubiculum volume http://www.ebi.ac.uk/efo/EFO_0009405 GCST006884 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Presubiculum volume 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 1 presubiculum volume http://www.ebi.ac.uk/efo/EFO_0009400 GCST006885 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Subiculum volume 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 4 subiculum volume http://www.ebi.ac.uk/efo/EFO_0009399 GCST006886 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Hippocampal subfield CA1 volume 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 3 hippocampal CA1 volume http://www.ebi.ac.uk/efo/EFO_0009394 GCST006887 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Hippocampal subfield CA3 volume 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 3 hippocampal CA3 volume http://www.ebi.ac.uk/efo/EFO_0009395 GCST006888 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Hippocampal subfield CA4 volume 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 5 hippocampal CA4 volume http://www.ebi.ac.uk/efo/EFO_0009396 GCST006889 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Dentate gyrus granule cell layer volume 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 5 granule cell layer dentate gyrus volume http://www.ebi.ac.uk/efo/EFO_0009403 GCST006890 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Dentate gyrus molecular layer volume 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 5 hippocampus molecular layer volume http://www.ebi.ac.uk/efo/EFO_0009397 GCST006891 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Hippocampal fissure volume 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 1 hippocampal fissure volume http://www.ebi.ac.uk/efo/EFO_0009404 GCST006892 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Hippocampal tail volume 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 7 hippocampal tail volume http://www.ebi.ac.uk/efo/EFO_0009398 GCST006870 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Fimbria volume 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 0 hippocampus fimbria volume http://www.ebi.ac.uk/efo/EFO_0009402 GCST006893 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. HATA volume 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 1 hippocampal amigdala transition area volume http://www.ebi.ac.uk/efo/EFO_0009401 GCST006894 Genome-wide genotyping array 21297 2019-01-11 30279459 van der Meer D 2018-10-02 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30279459 Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Parasubiculum volume 21,297 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 0 parasubiculum volume http://www.ebi.ac.uk/efo/EFO_0009405 GCST006895 Genome-wide genotyping array 21297 2019-04-09 30206230 Offenbacher S 2018-09-11 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30206230 GWAS for Interleukin-1β levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation. High IL-1beta levels in gingival crevicular fluid 4,910 European American individuals NA Affymetrix [656292] (imputed) 178 interleukin-1 beta measurement http://www.ebi.ac.uk/efo/EFO_0004812 GCST007542 Genome-wide genotyping array 4910 2018-10-22 30093639 Machiela MJ 2018-08-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30093639 Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility. Ewing sarcoma 733 European ancestry cases, 1,346 European ancestry controls 657 European ancestry cases, 4,078 European ancestry controls Illumina [6876682] (imputed) 4 Ewing sarcoma http://www.ebi.ac.uk/efo/EFO_0000174 GCST006467 Genome-wide genotyping array 2079 2018-09-19 30079052 Rujescu D 2018-07-20 Front Neurol www.ncbi.nlm.nih.gov/pubmed/30079052 Genome-Wide Association Study in Vestibular Neuritis: Involvement of the Host Factor for HSV-1 Replication. Vestibular neuritis 131 European ancestry cases, 2,609 German ancestry controls NA Affymetrix, Illumina [7813927] (imputed) 4 vestibular neuronitis http://www.ebi.ac.uk/efo/EFO_0007537 GCST006275 Genome-wide genotyping array 2740 2018-09-20 30068317 Li X 2018-08-01 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/30068317 Genome-wide association study of lung function and clinical implication in heavy smokers. Post bronchodilator percent predicted FEV1 in smoking 1,086 European ancestry COPD cases, 559 European ancestry controls NA Illumina [635970] 8 forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0004314 GCST006309 Genome-wide genotyping array 1645 2018-09-20 30068317 Li X 2018-08-01 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/30068317 Genome-wide association study of lung function and clinical implication in heavy smokers. Post bronchodilator FEV1/FVC ratio in smoking 1,086 European ancestry COPD cases, 559 European ancestry controls NA Illumina [635970] 8 FEV/FEC ratio http://www.ebi.ac.uk/efo/EFO_0004713 GCST006310 Genome-wide genotyping array 1645 2019-08-23 30088374 Park HW 2018-09-01 Allergy Asthma Immunol Res www.ncbi.nlm.nih.gov/pubmed/30088374 The Fas Signaling Pathway Is a Common Genetic Risk Factor for Severe Cutaneous Drug Adverse Reactions Across Diverse Drugs. Severe cutaneous adverse drug reactions 68 Korean ancestry cases, 272 Korean ancestry controls 38 Korean ancestry cases, 152 Korean ancestry controls Affymetrix [NR] 0 severe cutaneous adverse reaction http://www.ebi.ac.uk/efo/EFO_0006346 GCST008492 Genome-wide genotyping array 340 2019-02-01 30315195 Lee KY 2018-10-12 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30315195 Discovering Genetic Factors for psoriasis through exhaustively searching for significant second order SNP-SNP interactions. Psoriasis 2,280 cases, 2,002 controls NA NR [up to 790527] 136 psoriasis http://www.ebi.ac.uk/efo/EFO_0000676 GCST007023 Genome-wide genotyping array 4282 2018-10-12 30120083 Ferguson A 2018-08-14 EBioMedicine www.ncbi.nlm.nih.gov/pubmed/30120083 Genome-Wide Association Study of Circadian Rhythmicity in 71,500 UK Biobank Participants and Polygenic Association with Mood Instability. Relative amplitude of rest-activity cycles 77,440 European ancestry individuals NA Affymetrix [7969123] (imputed) 13 circadian rhythm http://www.ebi.ac.uk/efo/EFO_0004354 GCST006397 Genome-wide genotyping array 77440 2018-10-12 30120083 Ferguson A 2018-08-14 EBioMedicine www.ncbi.nlm.nih.gov/pubmed/30120083 Genome-Wide Association Study of Circadian Rhythmicity in 71,500 UK Biobank Participants and Polygenic Association with Mood Instability. Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) at least 2,700 European ancestry cases, at least 68,300 European ancestry controls NA Affymetrix [7969123] (imputed) 10 circadian rhythm http://www.ebi.ac.uk/efo/EFO_0004354 GCST006396 Genome-wide genotyping array 71000 2019-01-04 30196823 Blum S 2018-08-02 J Neuroimmunol www.ncbi.nlm.nih.gov/pubmed/30196823 Genome-wide association study in Guillain-Barré syndrome. Guillain-Barré syndrome 191 European ancestry cases, 639 European ancestry controls NA Illumina [579499] 0 Guillain-Barre syndrome http://www.ebi.ac.uk/efo/EFO_0007292 GCST006836 Genome-wide genotyping array 830 2019-01-11 30054458 Xue A 2018-07-27 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30054458 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. Type 2 diabetes 61,714 European ancestry cases, 1,178 Pakistani ancestry cases, 593,952 European ancestry controls, 2,472 Pakistani ancestry controls NA NR [5035015] (imputed) 139 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST006867 Genome-wide genotyping array 659316 2019-01-11 30054458 Xue A 2018-07-27 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30054458 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. Type 2 diabetes 21,147 European ancestry cases, 434,460 European ancestry controls NA NR [10849711] (imputed) 11 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST006868 Genome-wide genotyping array 455607 2018-11-28 30196971 Bray MJ 2018-09-01 Fertil Steril www.ncbi.nlm.nih.gov/pubmed/30196971 Transethnic and race-stratified genome-wide association study of fibroid characteristics in African American and European American women. Uterine fibroid number (single vs multiple) 636 African American or European ancestry female individuals with single fibroid, 822 African American or European ancestry female individuals with multiple fibroids NA Affymetrix [up to 9627525] (imputed) 8 uterine fibroid measurement http://www.ebi.ac.uk/efo/EFO_0009410 GCST006616 Genome-wide genotyping array 1458 2018-11-28 30196971 Bray MJ 2018-09-01 Fertil Steril www.ncbi.nlm.nih.gov/pubmed/30196971 Transethnic and race-stratified genome-wide association study of fibroid characteristics in African American and European American women. Uterine fibroid size (maximum dimension) 1,301 African American or European ancestry female individuals NA Affymetrix [up to 9596033] (imputed) 5 uterine fibroid measurement http://www.ebi.ac.uk/efo/EFO_0009410 GCST006618 Genome-wide genotyping array 1301 2018-11-28 30196971 Bray MJ 2018-09-01 Fertil Steril www.ncbi.nlm.nih.gov/pubmed/30196971 Transethnic and race-stratified genome-wide association study of fibroid characteristics in African American and European American women. Uterine fibroid size (maximum volume) 1,048 African American or European ancestry female individuals NA Affymetrix [up to 9597202] (imputed) 6 uterine fibroid measurement http://www.ebi.ac.uk/efo/EFO_0009410 GCST006617 Genome-wide genotyping array 1048 2019-03-19 30207284 Galvan-Femenia I 2018-03-01 Cancer Treat Res Commun www.ncbi.nlm.nih.gov/pubmed/30207284 Genomic profiling in advanced stage non-small-cell lung cancer patients with platinum-based chemotherapy identifies germline variants with prognostic value in SMYD2. Response to platinum-based chemotherapy in non-small-cell lung cancer (progression) 181 European ancestry individuals 356 European ancestry individuals Illumina [10307177] (imputed) 0 response to platinum based chemotherapy, disease progression measurement http://www.ebi.ac.uk/efo/EFO_0004647, http://www.ebi.ac.uk/efo/EFO_0008336 GCST007358 Genome-wide genotyping array 181 2018-12-06 30277614 Carlson JC 2018-09-11 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30277614 Genome-wide interaction studies identify sex-specific risk alleles for nonsyndromic orofacial clefts. Nonsyndromic cleft lip with or without cleft palate x sex interaction (2df test) 1,293 male cases, 849 female cases, 713 male controls, 987 female controls NA Illumina [up to 34985077] (imputed) 3 Cleft palate, sex interaction measurement, cleft lip http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0003959 GCST006680 Genome-wide genotyping array 3842 2019-08-23 30289108 Li W 2018-07-07 Eur Urol www.ncbi.nlm.nih.gov/pubmed/30289108 Genome-wide Scan Identifies Role for AOX1 in Prostate Cancer Survival. Prostate cancer mortality 245 European ancestry lethal cases, 808 European ancestry long-term survivor cases 172 European ancestry lethal cases, 1380 European ancestry long-term survivor cases Illumina [6126633] (imputed) 0 survival time, prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0000714, http://www.ebi.ac.uk/efo/EFO_0001663 GCST008493 Genome-wide genotyping array 1053 2019-03-20 30270018 Zhang Q 2018-09-09 J Diabetes Complications www.ncbi.nlm.nih.gov/pubmed/30270018 Additional common variants associated with type 2 diabetes and coronary artery disease detected using a pleiotropic cFDR method. Type 2 diabetes or coronary artery disease (pleiotropy) 12,171 European ancestry type 2 diabetes cases, 22,233 European ancestry coronary artery disease cases, 121,624 European ancestry controls NA NR [NR] 0 type II diabetes mellitus, coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001360, http://www.ebi.ac.uk/efo/EFO_0001645 GCST007359 Genome-wide genotyping array 156030 2018-11-28 30287856 Zheng R 2018-10-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30287856 Genome-wide association study identifies two risk loci for tuberculosis in Han Chinese. Tuberculosis 833 Han Chinese ancestry cases, 1,220 Han Chinese ancestry controls 2,116 Han Chinese ancestry cases, 3,870 Han Chinese ancestry controls Affymetrix [5374021] (imputed) 2 Tuberculosis http://www.orpha.net/ORDO/Orphanet_3389 GCST006619 Genome-wide genotyping array 2053 2018-11-29 30287806 Zhou H 2018-10-04 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/30287806 Genome-wide association study identifies glutamate ionotropic receptor GRIA4 as a risk gene for comorbid nicotine dependence and major depression. Nicotine dependence and major depression (severity of comorbidity) 3,724 African American individuals NA Illumina [9520174] (imputed) 52 nicotine dependence symptom count, depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0009262, http://www.ebi.ac.uk/efo/EFO_0007006 GCST006631 Genome-wide genotyping array 3724 2018-11-09 30271932 Oskarsson GR 2018-05-17 Commun Biol www.ncbi.nlm.nih.gov/pubmed/30271932 A truncating mutation in EPOR leads to hypo-responsiveness to erythropoietin with normal haemoglobin. Serum erythropoietin levels 2,994 Icelandic ancestry individuals, 1,193 non-array typed, familial imputed Icelandic ancestry individuals 68 Icelandic ancestry individuals Illumina [32554515] (imputed) 1 erythropoetin measurement http://www.ebi.ac.uk/efo/EFO_0008391 GCST006536 Genome-wide genotyping array 4187 2018-11-13 30087453 Yilmaz Z 2018-08-07 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30087453 Examination of the shared genetic basis of anorexia nervosa and obsessive-compulsive disorder. Anorexia nervosa or obsessive-compulsive disorder 3,495 European ancestry anorexia nervosa cases, 2,688 European ancestry obsessive-compulsive disorder cases, 18,013 European ancestry controls NA NR [7461827] (imputed) 3 anorexia nervosa, obsessive-compulsive disorder http://www.ebi.ac.uk/efo/EFO_0004215, http://www.ebi.ac.uk/efo/EFO_0004242 GCST006576 Genome-wide genotyping array 24196 2019-02-07 30046033 van Setten J 2018-07-25 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30046033 PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity. PR interval 92,340 European ancestry individuals NA Affymetrix, Illumina [2712613] (imputed) 44 PR interval http://www.ebi.ac.uk/efo/EFO_0004462 GCST007045 Genome-wide genotyping array 92340 2019-07-08 30199657 Xu J 2018-09-10 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/30199657 Omega-3 Fatty Acids and Genome-wide Interaction Analyses Reveal DPP10-Pulmonary Function Association. Pulmonary function (FEV1) x omega-3 PUFA (docosapentaenoic acid) interaction (2df) 11,165 European ancestry individuals, 797 African ancestry individuals 1,141 European ancestry individuals, 546 African ancestry individuals Affymetrix, Illumina [7200000] (imputed) 0 forced expiratory volume, docosapentaenoic acid measurement http://www.ebi.ac.uk/efo/EFO_0004314, http://www.ebi.ac.uk/efo/EFO_0006809 GCST008101 Genome-wide genotyping array 11962 2019-07-08 30199657 Xu J 2018-09-10 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/30199657 Omega-3 Fatty Acids and Genome-wide Interaction Analyses Reveal DPP10-Pulmonary Function Association. Pulmonary function (FVC) x omega-3 PUFA (docosapentaenoic acid) interaction (2df) 11,165 European ancestry individuals, 797 African ancestry individuals 1,141 European ancestry individuals, 546 African ancestry individuals Affymetrix, Illumina [7200000] (imputed) 0 docosapentaenoic acid measurement, vital capacity http://www.ebi.ac.uk/efo/EFO_0006809, http://www.ebi.ac.uk/efo/EFO_0004312 GCST008100 Genome-wide genotyping array 11962 2019-07-08 30199657 Xu J 2018-09-10 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/30199657 Omega-3 Fatty Acids and Genome-wide Interaction Analyses Reveal DPP10-Pulmonary Function Association. Pulmonary function (FVC) x omega-3 PUFA (docosahexaenoic acid) interaction (2df) 11,165 European ancestry individuals, 797 African ancestry individuals 1,141 European ancestry individuals, 546 African ancestry individuals Affymetrix, Illumina [7200000] (imputed) 1 docosahexaenoic acid measurement, vital capacity http://www.ebi.ac.uk/efo/EFO_0007761, http://www.ebi.ac.uk/efo/EFO_0004312 GCST008099 Genome-wide genotyping array 11962 2019-07-08 30199657 Xu J 2018-09-10 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/30199657 Omega-3 Fatty Acids and Genome-wide Interaction Analyses Reveal DPP10-Pulmonary Function Association. Pulmonary function (FEV1) x omega-3 PUFA (docosahexaenoic acid) interaction (2df) 11,165 European ancestry individuals, 797 African ancestry individuals 1,141 European ancestry individuals, 546 African ancestry individuals Affymetrix, Illumina [7200000] (imputed) 0 docosahexaenoic acid measurement, forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0007761, http://www.ebi.ac.uk/efo/EFO_0004314 GCST008102 Genome-wide genotyping array 11962 2018-10-25 30049742 Terzikhan N 2018-07-26 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/30049742 Heritability and genome-wide association study of diffusing capacity of the lung. Diffusing capacity of the lung for carbon monoxide traits 8,372 European ancestry individuals NA Affymetrix, Illumina [NR] 8 diffusing capacity of the lung for carbon monoxide http://www.ebi.ac.uk/efo/EFO_0009369 GCST006473 Genome-wide genotyping array 8372 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-cytomegalovirus IgG seropositivity 347 Metropolitan French ancestry cases, 653 Metropolitan French ancestry controls NA Illumina [5699237] (imputed) 0 cytomegalovirus seropositivity http://www.ebi.ac.uk/efo/EFO_0007037 GCST006331 Genome-wide genotyping array 1000 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-Epstein-Barr virus nuclear antigen (EBNA) IgG seropositivity 914 Metropolitan French ancestry cases, 86 Metropolitan French ancestry controls NA Illumina [5699237] (imputed) 0 Epstein Barr virus nuclear antigen-1 seropositivity http://www.ebi.ac.uk/efo/EFO_0009271 GCST006332 Genome-wide genotyping array 1000 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-Epstein-Barr virus viral capsid antigen (VCA) IgG seropositivity 956 Metropolitan French ancestry cases, 44 Metropolitan French ancestry controls NA Illumina [5699237] (imputed) 0 Epstein Barr viral capsid antigen seropositivity http://www.ebi.ac.uk/efo/EFO_0009272 GCST006333 Genome-wide genotyping array 1000 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-Epstein-Barr virus early antigen (EA) IgG seropositivity 91 Metropolitan French ancestry cases, 909 Metropolitan French ancestry controls NA Illumina [5699237] (imputed) 0 Epstein-Barr virus early antigen seropositivity http://www.ebi.ac.uk/efo/EFO_0009338 GCST006330 Genome-wide genotyping array 1000 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-herpes simplex virus 1 IgG seropositivity 645 Metropolitan French ancestry cases, 355 Metropolitan French ancestry controls NA Illumina [5699237] (imputed) 0 HSV1 seropositivity http://www.ebi.ac.uk/efo/EFO_0007050 GCST006334 Genome-wide genotyping array 1000 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-herpes simplex virus 2 IgG seropositivity 208 Metropolitan French ancestry cases, 792 Metropolitan French ancestry controls NA Illumina [5699237] (imputed) 0 Herpes simplex virus 2 seropositivity http://www.ebi.ac.uk/efo/EFO_0009339 GCST006335 Genome-wide genotyping array 1000 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-varicella zoster virus IgG seropositivity 931 Metropolitan French ancestry cases, 69 Metropolitan French ancestry controls NA Illumina [5699237] (imputed) 0 Varicella zoster virus seropositivity http://www.ebi.ac.uk/efo/EFO_0009340 GCST006336 Genome-wide genotyping array 1000 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-helicobacter pylori IgG seropositivity 175 Metropolitan French ancestry cases, 825 Metropolitan French ancestry controls NA Illumina [5699237] (imputed) 0 Helicobacter pylori seropositivity http://www.ebi.ac.uk/efo/EFO_0009341 GCST006337 Genome-wide genotyping array 1000 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-Toxoplasma gondii IgG seropositivity 559 Metropolitan French ancestry cases, 441 Metropolitan French ancestry controls NA Illumina [5699237] (imputed) 0 Toxoplasma gondii seropositivity http://www.ebi.ac.uk/efo/EFO_0007047 GCST006338 Genome-wide genotyping array 1000 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-influenza A virus IgG seropositivity 777 Metropolitan French ancestry cases, 223 Metropolitan French ancestry controls NA Illumina [5699237] (imputed) 0 Influenza A seropositivity http://www.ebi.ac.uk/efo/EFO_0007038 GCST006339 Genome-wide genotyping array 1000 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-measles virus IgG seropositivity 885 Metropolitan French ancestry cases, 115 Metropolitan French ancestry controls NA Illumina [5699237] (imputed) 0 Measles virus seropositivity http://www.ebi.ac.uk/efo/EFO_0009342 GCST006340 Genome-wide genotyping array 1000 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-mumps virus IgG seropositivity 912 Metropolitan French ancestry cases, 88 Metropolitan French ancestry controls NA Illumina [5699237] (imputed) 0 Mumps virus seropositivity http://www.ebi.ac.uk/efo/EFO_0009343 GCST006341 Genome-wide genotyping array 1000 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-rubella virus IgG seropositivity 935 Metropolitan French ancestry cases, 65 Metropolitan French ancestry controls NA Illumina [5699237] (imputed) 0 Rubella virus seropositivity http://www.ebi.ac.uk/efo/EFO_0009344 GCST006342 Genome-wide genotyping array 1000 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-hepatitis B virus surface antigen (HBs) IgG seropositivity 508 Metropolitan French ancestry cases, 492 Metropolitan French ancestry controls NA Illumina [5699237] (imputed) 0 Hepatitis B virus surface antigen seropositivity http://www.ebi.ac.uk/efo/EFO_0009345 GCST006356 Genome-wide genotyping array 1000 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-hepatitis B virus core antigen (HBc) IgG seropositivity 15 Metropolitan French ancestry cases, 985 Metropolitan French ancestry controls NA Illumina [5699237] (imputed) 0 Hepatitis B virus core antigen seropositivity http://www.ebi.ac.uk/efo/EFO_0009346 GCST006343 Genome-wide genotyping array 1000 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. IgG levels 1000 Metropolitan French ancestry individuals NA Illumina [5699237] (imputed) 0 serum IgG measurement http://www.ebi.ac.uk/efo/EFO_0004565 GCST006357 Genome-wide genotyping array 1000 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. IgM levels 1000 Metropolitan French ancestry individuals NA Illumina [5699237] (imputed) 0 serum IgM measurement http://www.ebi.ac.uk/efo/EFO_0004993 GCST006359 Genome-wide genotyping array 1000 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. IgA levels 1000 Metropolitan French ancestry individuals NA Illumina [5699237] (imputed) 1 serum IgA measurement http://www.ebi.ac.uk/efo/EFO_0004912 GCST006360 Genome-wide genotyping array 1000 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. IgE levels 1000 Metropolitan French ancestry individuals NA Illumina [5699237] (imputed) 0 serum IgE measurement http://www.ebi.ac.uk/efo/EFO_0004579 GCST006358 Genome-wide genotyping array 1000 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-cytomegalovirus IgG levels 347 Metropolitan French ancestry individuals NA Illumina [5699237] (imputed) 0 Anti-cytomegalovirus IgG measurement http://www.ebi.ac.uk/efo/EFO_0009347 GCST006344 Genome-wide genotyping array 347 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-Epstein-Barr virus nuclear antigen (EBNA) IgG levels 914 Metropolitan French ancestry individuals NA Illumina [5699237] (imputed) 2 Epstein Barr virus nuclear antigen 1 IgG measurement http://www.ebi.ac.uk/efo/EFO_0007790 GCST006361 Genome-wide genotyping array 914 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-Epstein-Barr virus viral capsid antigen (VCA) IgG levels 956 Metropolitan French ancestry individuals NA Illumina [5699237] (imputed) 0 Epstein Barr viral capsid antigen IgG measurement http://www.ebi.ac.uk/efo/EFO_0009274 GCST006362 Genome-wide genotyping array 956 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-Epstein-Barr virus early antigen (EA) IgG levels 91 Metropolitan French ancestry individuals NA Illumina [5699237] (imputed) 0 Anti-Epstein-Barr virus early antigen IgG measurement http://www.ebi.ac.uk/efo/EFO_0009348 GCST006345 Genome-wide genotyping array 91 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-herpes simplex virus 1 IgG levels 645 Metropolitan French ancestry individuals NA Illumina [5699237] (imputed) 0 Anti-herpes simplex virus 1 IgG measurement http://www.ebi.ac.uk/efo/EFO_0009349 GCST006346 Genome-wide genotyping array 645 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-herpes simplex virus 2 IgG levels 208 Metropolitan French ancestry individuals NA Illumina [5699237] (imputed) 0 Anti-herpes simplex virus 2 IgG measurement http://www.ebi.ac.uk/efo/EFO_0009350 GCST006347 Genome-wide genotyping array 208 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-varicella zoster virus IgG levels 931 Metropolitan French ancestry individuals NA Illumina [5699237] (imputed) 0 Anti-varicella zoster virus IgG measurement http://www.ebi.ac.uk/efo/EFO_0009351 GCST006348 Genome-wide genotyping array 931 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-helicobacter pylori IgG levels 175 Metropolitan French ancestry individuals NA Illumina [5699237] (imputed) 0 anti-Helicobacter pylori serum IgG measurement http://www.ebi.ac.uk/efo/EFO_0005247 GCST006363 Genome-wide genotyping array 175 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-Toxoplasma gondii IgG levels 559 Metropolitan French ancestry individuals NA Illumina [5699237] (imputed) 0 Anti-Toxoplasma gondii IgG measurement http://www.ebi.ac.uk/efo/EFO_0009353 GCST006349 Genome-wide genotyping array 559 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-influenza A virus IgG levels 777 Metropolitan French ancestry individuals NA Illumina [5699237] (imputed) 0 Anti-influenza A virus IgG measurement http://www.ebi.ac.uk/efo/EFO_0009354 GCST006350 Genome-wide genotyping array 777 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-measles virus IgG levels 885 Metropolitan French ancestry individuals NA Illumina [5699237] (imputed) 0 Anti-measles virus IgG measurement http://www.ebi.ac.uk/efo/EFO_0009355 GCST006351 Genome-wide genotyping array 885 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-mumps virus IgG levels 912 Metropolitan French ancestry individuals NA Illumina [5699237] (imputed) 0 Anti-mumps virus IgG measurement http://www.ebi.ac.uk/efo/EFO_0009356 GCST006352 Genome-wide genotyping array 912 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-rubella virus IgG levels 935 Metropolitan French ancestry individuals NA Illumina [5699237] (imputed) 2 Anti-rubella virus IgG measurement http://www.ebi.ac.uk/efo/EFO_0009357 GCST006353 Genome-wide genotyping array 935 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-hepatitis B virus surface antigen (HBs) IgG levels 508 Metropolitan French ancestry individuals NA Illumina [5699237] (imputed) 0 Anti-hepatitis B virus surface antigen IgG measurement http://www.ebi.ac.uk/efo/EFO_0009358 GCST006354 Genome-wide genotyping array 508 2018-09-25 30053915 Scepanovic P 2018-07-27 Genome Med www.ncbi.nlm.nih.gov/pubmed/30053915 Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines. Anti-hepatitis B virus core antigen (HBc) IgG levels 15 Metropolitan French ancestry individuals NA Illumina [5699237] (imputed) 0 Anti-hepatitis B virus core antigen IgG measurement http://www.ebi.ac.uk/efo/EFO_0009359 GCST006355 Genome-wide genotyping array 15 2019-03-27 29936532 Colodro-Conde L 2018-06-23 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/29936532 Association Between Population Density and Genetic Risk for Schizophrenia. Socioeconomic status of place of residence 456,426 European ancestry individuals NA Affymetrix [12272635] (imputed) 0 place of residence measurement http://www.ebi.ac.uk/efo/EFO_0009583 GCST007422 Genome-wide genotyping array 456426 2019-03-27 29936532 Colodro-Conde L 2018-06-23 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/29936532 Association Between Population Density and Genetic Risk for Schizophrenia. Population density of place of residence 504,130 European ancestry individuals NA Affymetrix, Illumina, Perlegen [up to 12272635] (imputed) 0 place of residence measurement http://www.ebi.ac.uk/efo/EFO_0009583 GCST007421 Genome-wide genotyping array 504130 2018-10-10 30054594 MacGregor S 2018-07-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30054594 Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma. Intraocular pressure 133,492 European ancestry individuals NA Affymetrix, Illumina [up to 40000000] (imputed) 106 intraocular pressure measurement http://www.ebi.ac.uk/efo/EFO_0004695 GCST006394 Genome-wide genotyping array 133492 2018-10-10 30054594 MacGregor S 2018-07-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30054594 Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma. Glaucoma 11,018 European ancestry cases, 126,068 European ancestry controls NA Affymetrix [up to 40000000] (imputed) 48 glaucoma http://www.ebi.ac.uk/efo/EFO_0000516 GCST006395 Genome-wide genotyping array 137086 2018-10-18 30213928 Went M 2018-09-13 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30213928 Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma. Multiple myeloma 8,197 European ancestry cases, 241,468 European ancestry controls 1,777 European ancestry cases, 6,088 European ancestry controls Illumina [up to 10291845] (imputed) 9 multiple myeloma http://www.ebi.ac.uk/efo/EFO_0001378 GCST006432 Genome-wide genotyping array 249665 2018-11-07 24869959 Jacobs LC 2014-08-01 JAMA Dermatol www.ncbi.nlm.nih.gov/pubmed/24869959 Intrinsic and extrinsic risk factors for sagging eyelids. Upper eyelid sagging severity 6,631 European ancestry individuals NA Illumina [at least 2149245] (imputed) 22 eyelid sagging measurement http://www.ebi.ac.uk/efo/EFO_0009360 GCST006522 Genome-wide genotyping array 6631 2018-11-02 30218097 Munz M 2018-09-14 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30218097 Meta-analysis of genome-wide association studies of aggressive and chronic periodontitis identifies two novel risk loci. Periodontitis 4,102 European ancestry cases, 8,489 European ancestry controls 993 European ancestry cases, 1,419 European ancestry controls Affymetrix, Illumina [1722107] (imputed) 12 periodontitis http://www.ebi.ac.uk/efo/EFO_0000649 GCST006486 Genome-wide genotyping array 12591 2019-02-11 30277654 Yokoshima Y 2018-09-14 Neuropsychopharmacol Rep www.ncbi.nlm.nih.gov/pubmed/30277654 Gamma-aminobutyric acid transaminase genetic polymorphism is a candidate locus for responsiveness to opioid analgesics in patients with cancer pain: An exploratory study. Response to opioid analgesics in cancer (pain decrease) 71 Japanese ancestry individuals NA Illumina [771433] 2 response to opioid http://www.ebi.ac.uk/efo/EFO_0008541 GCST007106 Genome-wide genotyping array 71 2018-11-30 30276832 Edwards AC 2018-10-01 Alcohol Clin Exp Res www.ncbi.nlm.nih.gov/pubmed/30276832 Meta-Analysis of Genetic Influences on Initial Alcohol Sensitivity. Initial alcohol sensitivity 6,039 European ancestry individuals, 892 African ancestry individuals, 408 American ancestry individuals NA Affymetrix, Illumina [15642250] (imputed) 34 response to alcohol http://www.ebi.ac.uk/efo/EFO_0005526 GCST006633 Genome-wide genotyping array 7339 2020-10-23 32665545 van der Meer D 2020-07-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32665545 Understanding the genetic determinants of the brain with MOSTest. Brain morphology (MOSTest) 26,502 European ancestry individuals NA NR [7428630] (imputed) 346 brain measurement, neuroimaging measurement http://www.ebi.ac.uk/efo/EFO_0004464, http://www.ebi.ac.uk/efo/EFO_0004346 GCST010703 Genome-wide genotyping array 26502 2020-10-23 32665545 van der Meer D 2020-07-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32665545 Understanding the genetic determinants of the brain with MOSTest. Cortical thickness (MOSTest) 26,502 European ancestry individuals NA NR [7428630] (imputed) 70 cortical thickness, neuroimaging measurement http://www.ebi.ac.uk/efo/EFO_0004840, http://www.ebi.ac.uk/efo/EFO_0004346 GCST010700 Genome-wide genotyping array 26502 2020-10-23 32665545 van der Meer D 2020-07-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32665545 Understanding the genetic determinants of the brain with MOSTest. Subcortical volume (MOSTest) 26,502 European ancestry individuals NA NR [7428630] (imputed) 177 neuroimaging measurement, brain volume measurement http://www.ebi.ac.uk/efo/EFO_0004346, http://www.ebi.ac.uk/efo/EFO_0006930 GCST010702 Genome-wide genotyping array 26502 2020-10-23 32665545 van der Meer D 2020-07-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32665545 Understanding the genetic determinants of the brain with MOSTest. Brain morphology (min-P) 26,502 European ancestry individuals NA NR [7428630] (imputed) 113 brain measurement, neuroimaging measurement http://www.ebi.ac.uk/efo/EFO_0004464, http://www.ebi.ac.uk/efo/EFO_0004346 GCST010699 Genome-wide genotyping array 26502 2020-10-23 32665545 van der Meer D 2020-07-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32665545 Understanding the genetic determinants of the brain with MOSTest. Cortical surface area (MOSTest) 26,502 European ancestry individuals NA NR [7428630] (imputed) 138 cortical surface area measurement, neuroimaging measurement http://www.ebi.ac.uk/efo/EFO_0010736, http://www.ebi.ac.uk/efo/EFO_0004346 GCST010701 Genome-wide genotyping array 26502 2020-10-23 32665545 van der Meer D 2020-07-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32665545 Understanding the genetic determinants of the brain with MOSTest. Subcortical volume (min-P) 26,502 European ancestry individuals NA NR [7428630] (imputed) 89 neuroimaging measurement, brain volume measurement http://www.ebi.ac.uk/efo/EFO_0004346, http://www.ebi.ac.uk/efo/EFO_0006930 GCST010698 Genome-wide genotyping array 26502 2020-10-23 32665545 van der Meer D 2020-07-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32665545 Understanding the genetic determinants of the brain with MOSTest. Cortical surface area (min-P) 26,502 European ancestry individuals NA NR [7428630] (imputed) 53 cortical surface area measurement, neuroimaging measurement http://www.ebi.ac.uk/efo/EFO_0010736, http://www.ebi.ac.uk/efo/EFO_0004346 GCST010697 Genome-wide genotyping array 26502 2020-10-23 32665545 van der Meer D 2020-07-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32665545 Understanding the genetic determinants of the brain with MOSTest. Cortical thickness (min-P) 26,502 European ancestry individuals NA NR [7428630] (imputed) 23 cortical thickness, neuroimaging measurement http://www.ebi.ac.uk/efo/EFO_0004840, http://www.ebi.ac.uk/efo/EFO_0004346 GCST010696 Genome-wide genotyping array 26502 2018-11-12 30273415 Hatzikotoulas K 2018-05-31 Commun Biol www.ncbi.nlm.nih.gov/pubmed/30273415 Genome-wide association study of developmental dysplasia of the hip identifies an association with GDF5. Developmental dysplasia of the hip 770 European ancestry cases, 3,364 European ancestry controls 1,129 European ancestry cases, 4,652 European ancestry controls Illumina [256867] 3 developmental dysplasia of the hip http://www.ebi.ac.uk/efo/EFO_1000648 GCST006566 Genome-wide genotyping array 4134 2019-01-25 30087447 Aubart M 2018-08-07 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30087447 Association of modifiers and other genetic factors explain Marfan syndrome clinical variability. Severe aortic features in Marfan syndrome 51 European ancestry cases, 47 European ancestry controls NA Illumina [at least 701570] (imputed) 4 thoracic aortic aneurysm http://www.ebi.ac.uk/efo/EFO_0004282 GCST006957 Genome-wide genotyping array 98 2021-07-27 33483693 Clements CC 2021-01-22 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/33483693 Genome-wide association study of patients with a severe major depressive episode treated with electroconvulsive therapy. Major depressive episode treated with electroconvulsive therapy 2,725 European ancestry cases, 3,290 European ancestry controls NA Illumina [NR] (imputed) 30 major depressive episode http://www.ebi.ac.uk/efo/EFO_0007634 GCST012095 Genome-wide genotyping array 6015 2021-07-27 33483693 Clements CC 2021-01-22 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/33483693 Genome-wide association study of patients with a severe major depressive episode treated with electroconvulsive therapy. Major depressive disorder and major depressive episode treated with electroconvulsive therapy 1,796 European ancestry cases, 3,290 European ancestry controls NA Illumina [NR] (imputed) 22 major depressive episode, major depressive disorder http://www.ebi.ac.uk/efo/EFO_0007634, http://purl.obolibrary.org/obo/MONDO_0002009 GCST012094 Genome-wide genotyping array 5086 2019-01-15 30320955 Baird DA 2018-10-15 J Bone Miner Res www.ncbi.nlm.nih.gov/pubmed/30320955 Identification of novel loci associated with hip shape: a meta-analysis of genome-wide association studies. Hip shape (DXA scan) 10,217 European ancestry individuals, 5,717 individuals NA Illumina [7191926] (imputed) 12 hip geometry http://www.ebi.ac.uk/efo/EFO_0004685 GCST006903 Genome-wide genotyping array 15934 2019-02-20 30338293 Wallen ZD 2018-10-05 Neurol Genet www.ncbi.nlm.nih.gov/pubmed/30338293 Plasticity-related gene 3 (LPPR1) and age at diagnosis of Parkinson disease. Parkinson's disease (age at diagnosis) 1,950 European ancestry cases 726 European ancestry cases Illumina [8500000] (imputed) 1 Parkinson's disease, age at diagnosis http://www.ebi.ac.uk/efo/EFO_0002508, http://www.ebi.ac.uk/efo/EFO_0004918 GCST007198 Genome-wide genotyping array 1950 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Hyperinsulinemia in non-obese individuals 8,363 European ancestry women NA NR [18717781] (imputed) 0 fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004466 GCST007769 Genome-wide genotyping array 8363 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Hyperinsulinemia in higher physical activity 4,976 European ancestry women NA NR [18717781] (imputed) 0 fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004466 GCST007770 Genome-wide genotyping array 4976 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Hyperinsulinemia in lower physical activity 6,818 European ancestry women NA NR [18717781] (imputed) 2 fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004466 GCST007771 Genome-wide genotyping array 6818 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Hyperinsulinemia in more-fat diet 10,707 European ancestry women NA NR [18717781] (imputed) 0 fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004466 GCST007772 Genome-wide genotyping array 10707 2019-05-09 30327367 Jung SY 2018-10-16 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/30327367 Genome-wide meta-analysis of gene-environmental interaction for insulin-resistance phenotypes and breast cancer risk in postmenopausal women. Hyperinsulinemia in less-fat diet 1,087 European ancestry women NA NR [18717781] (imputed) 1 fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004466 GCST007773 Genome-wide genotyping array 1087 2019-04-04 28700999 Yang CK 2017-07-13 Cell Physiol Biochem www.ncbi.nlm.nih.gov/pubmed/28700999 Genome-Wide Association Study of MKI67 Expression and its Clinical Implications in HBV-Related Hepatocellular Carcinoma in Southern China. Hepatitis B virus-related hepatocellular carcinoma 195 Han Chinese ancestry cases 97 Han Chinese ancestry cases Illumina [242901] 0 hepatocellular carcinoma http://www.ebi.ac.uk/efo/EFO_0000182 GCST007514 Targeted genotyping array [Exome array] 195 2021-07-28 33095540 Sherman BT 2020-10-20 AIDS www.ncbi.nlm.nih.gov/pubmed/33095540 Genome-wide association study of high-sensitivity C-reactive protein, D-dimer and Interleukin-6 levels in multi-ethnic HIV+ cohorts. D-dimer levels in HIV infection 4,675 European ancestry individuals, 1,732 African ancestry individuals, 645 Admixed American individuals NA Affymetrix [up to 12642786] (imputed) 5 D dimer measurement http://www.ebi.ac.uk/efo/EFO_0004507 GCST012139 Genome-wide genotyping array 7052 2021-07-28 33095540 Sherman BT 2020-10-20 AIDS www.ncbi.nlm.nih.gov/pubmed/33095540 Genome-wide association study of high-sensitivity C-reactive protein, D-dimer and Interleukin-6 levels in multi-ethnic HIV+ cohorts. Interleukin-6 levels in HIV infection 4,675 European ancestry individuals, 1,732 African ancestry individuals, 645 Admixed American individuals NA Affymetrix [up to 12642786] (imputed) 3 interleukin-6 measurement http://www.ebi.ac.uk/efo/EFO_0004810 GCST012138 Genome-wide genotyping array 7052 2021-07-28 33095540 Sherman BT 2020-10-20 AIDS www.ncbi.nlm.nih.gov/pubmed/33095540 Genome-wide association study of high-sensitivity C-reactive protein, D-dimer and Interleukin-6 levels in multi-ethnic HIV+ cohorts. High-sensitivity C-reactive protein levels in HIV infection 4,675 European ancestry individuals, 1,732 African ancestry individuals, 645 Admixed American individuals NA Affymetrix [up to 12642786] (imputed) 4 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST012140 Genome-wide genotyping array 7052 2018-10-17 30178632 Meng W 2018-09-04 Acta Ophthalmol www.ncbi.nlm.nih.gov/pubmed/30178632 A genome-wide association study suggests new evidence for an association of the NADPH Oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes. Severe diabetic retinopathy in type 2 diabetes 560 Scottish ancestry proliferative or severe background retinopathy cases, 4,106 Scottish ancestry mild or no retinopathy controls NA Affymetrix, Illumina [6585471] (imputed) 2 diabetic retinopathy http://www.ebi.ac.uk/efo/EFO_0003770 GCST006424 Genome-wide genotyping array 4666 2021-06-23 33321125 Nasu T 2020-12-13 Int J Cardiol www.ncbi.nlm.nih.gov/pubmed/33321125 A genome-wide association study for highly sensitive cardiac troponin T levels identified a novel genetic variation near a RBAK-ZNF890P locus in the Japanese general population. HIgh-sensitivity cardiac troponin T levels (high vs low) 967 Japanese ancestry high hs-cTnT individuals, 2,816 Japanese ancestry low hs-cTnT individuals 190 Japanese ancestry high hs-cTnT individuals, 708 Japanese ancestry low hs-cTnT individuals Illumina [7151284] (imputed) 4 cardiac troponin T measurement http://www.ebi.ac.uk/efo/EFO_0005043 GCST011962 Genome-wide genotyping array 3783 2021-06-23 33321125 Nasu T 2020-12-13 Int J Cardiol www.ncbi.nlm.nih.gov/pubmed/33321125 A genome-wide association study for highly sensitive cardiac troponin T levels identified a novel genetic variation near a RBAK-ZNF890P locus in the Japanese general population. High-sensitivity cardiac troponin T levels 3,783 Japanese ancestry individuals 898 Japanese ancestry individuals Illumina [7151284] (imputed) 3 cardiac troponin T measurement http://www.ebi.ac.uk/efo/EFO_0005043 GCST011961 Genome-wide genotyping array 3783 2021-09-29 33143745 Andlauer TFM 2020-11-04 BMC Med www.ncbi.nlm.nih.gov/pubmed/33143745 Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS. Neutralising antibody response to interferon beta therapy in multiple sclerosis (presence of antibodies; IFNβ-1a subcutaneous) up to 2,000 individuals up to 757 individuals Illumina [9096778] (imputed) 1 response to interferon beta, anti-drug antibody measurement http://purl.obolibrary.org/obo/GO_0035456, http://www.ebi.ac.uk/efo/EFO_0010559 GCST012416 Genome-wide genotyping array 2000 2021-09-29 33143745 Andlauer TFM 2020-11-04 BMC Med www.ncbi.nlm.nih.gov/pubmed/33143745 Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS. Neutralising antibody response to interferon beta therapy in multiple sclerosis (presence of antibodies; IFNβ-1a subcutaneous and intramuscular) up to 2,000 individuals up to 757 individuals Illumina [9096778] (imputed) 1 response to interferon beta, anti-drug antibody measurement http://purl.obolibrary.org/obo/GO_0035456, http://www.ebi.ac.uk/efo/EFO_0010559 GCST012415 Genome-wide genotyping array 2000 2021-09-29 33143745 Andlauer TFM 2020-11-04 BMC Med www.ncbi.nlm.nih.gov/pubmed/33143745 Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS. Neutralising antibody response to interferon beta therapy in multiple sclerosis (presence of antibodies; IFNβ-1b subcutaneous) up to 2,000 individuals up to 757 individuals Illumina [9096778] (imputed) 2 response to interferon beta, anti-drug antibody measurement http://purl.obolibrary.org/obo/GO_0035456, http://www.ebi.ac.uk/efo/EFO_0010559 GCST012414 Genome-wide genotyping array 2000 2021-09-29 33143745 Andlauer TFM 2020-11-04 BMC Med www.ncbi.nlm.nih.gov/pubmed/33143745 Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS. Neutralising antibody response to interferon beta therapy in multiple sclerosis (antibody titre; all treatment preparations) up to 2,000 individuals up to 757 individuals Illumina [9096778] (imputed) 1 response to interferon beta, anti-drug antibody measurement http://purl.obolibrary.org/obo/GO_0035456, http://www.ebi.ac.uk/efo/EFO_0010559 GCST012413 Genome-wide genotyping array 2000 2021-09-29 33143745 Andlauer TFM 2020-11-04 BMC Med www.ncbi.nlm.nih.gov/pubmed/33143745 Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS. Neutralising antibody response to interferon beta therapy in multiple sclerosis (antibody titre; IFNβ-1a subcutaneous) up to 2,000 individuals up to 757 individuals Illumina [9096778] (imputed) 1 response to interferon beta, anti-drug antibody measurement http://purl.obolibrary.org/obo/GO_0035456, http://www.ebi.ac.uk/efo/EFO_0010559 GCST012412 Genome-wide genotyping array 2000 2021-09-29 33143745 Andlauer TFM 2020-11-04 BMC Med www.ncbi.nlm.nih.gov/pubmed/33143745 Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS. Neutralising antibody response to interferon beta therapy in multiple sclerosis (antibody titre; IFNβ-1a subcutaneous and intramuscular) up to 2,000 individuals up to 757 individuals Illumina [9096778] (imputed) 1 response to interferon beta, anti-drug antibody measurement http://purl.obolibrary.org/obo/GO_0035456, http://www.ebi.ac.uk/efo/EFO_0010559 GCST012411 Genome-wide genotyping array 2000 2021-09-29 33143745 Andlauer TFM 2020-11-04 BMC Med www.ncbi.nlm.nih.gov/pubmed/33143745 Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS. Neutralising antibody response to interferon beta therapy in multiple sclerosis (antibody titre; IFNβ-1b subcutaneous) up to 2,000 individuals up to 757 individuals Illumina [9096778] (imputed) 2 response to interferon beta, anti-drug antibody measurement http://purl.obolibrary.org/obo/GO_0035456, http://www.ebi.ac.uk/efo/EFO_0010559 GCST012410 Genome-wide genotyping array 2000 2021-09-29 33143745 Andlauer TFM 2020-11-04 BMC Med www.ncbi.nlm.nih.gov/pubmed/33143745 Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS. Binding antibody response to interferon beta therapy in multiple sclerosis (antibody levels; all treatment preparations) up to 2,000 individuals up to 757 individuals Illumina [9096778] (imputed) 5 response to interferon beta, anti-drug antibody measurement http://purl.obolibrary.org/obo/GO_0035456, http://www.ebi.ac.uk/efo/EFO_0010559 GCST012409 Genome-wide genotyping array 2000 2021-09-29 33143745 Andlauer TFM 2020-11-04 BMC Med www.ncbi.nlm.nih.gov/pubmed/33143745 Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS. Binding antibody response to interferon beta therapy in multiple sclerosis (antibody levels; IFNβ-1a subcutaneous) up to 2,000 individuals up to 757 individuals Illumina [9096778] (imputed) 1 response to interferon beta, anti-drug antibody measurement http://purl.obolibrary.org/obo/GO_0035456, http://www.ebi.ac.uk/efo/EFO_0010559 GCST012408 Genome-wide genotyping array 2000 2021-09-29 33143745 Andlauer TFM 2020-11-04 BMC Med www.ncbi.nlm.nih.gov/pubmed/33143745 Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS. Binding antibody response to interferon beta therapy in multiple sclerosis (antibody levels; IFNβ-1a subcutaneous and intramuscular) up to 2,000 individuals up to 757 individuals Illumina [9096778] (imputed) 3 response to interferon beta, anti-drug antibody measurement http://purl.obolibrary.org/obo/GO_0035456, http://www.ebi.ac.uk/efo/EFO_0010559 GCST012407 Genome-wide genotyping array 2000 2021-09-29 33143745 Andlauer TFM 2020-11-04 BMC Med www.ncbi.nlm.nih.gov/pubmed/33143745 Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS. Binding antibody response to interferon beta therapy in multiple sclerosis (antibody levels; IFNβ-1b subcutaneous) up to 2,000 individuals up to 757 individuals Illumina [9096778] (imputed) 2 response to interferon beta, anti-drug antibody measurement http://purl.obolibrary.org/obo/GO_0035456, http://www.ebi.ac.uk/efo/EFO_0010559 GCST012406 Genome-wide genotyping array 2000 2021-09-29 33143745 Andlauer TFM 2020-11-04 BMC Med www.ncbi.nlm.nih.gov/pubmed/33143745 Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS. Neutralising antibody response to interferon beta therapy in multiple sclerosis (presence of antibodies; all treatment preparations) up to 2,000 individuals up to 757 individuals Illumina [9096778] (imputed) 1 response to interferon beta, anti-drug antibody measurement http://purl.obolibrary.org/obo/GO_0035456, http://www.ebi.ac.uk/efo/EFO_0010559 GCST012417 Genome-wide genotyping array 2000 2019-03-21 30202041 Otani T 2018-09-10 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30202041 Exploring predictive biomarkers from clinical genome-wide association studies via multidimensional hierarchical mixture models. Progression-free survival response to gemcitabine in breast cancer 1,621 treated cases, 1,668 untreated cases NA Illumina [424121] 0 progression free survival, response to gemcitabine http://www.ebi.ac.uk/efo/EFO_0004920, http://purl.obolibrary.org/obo/GO_0036272 GCST007365 Genome-wide genotyping array 3289 2019-03-21 30202041 Otani T 2018-09-10 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30202041 Exploring predictive biomarkers from clinical genome-wide association studies via multidimensional hierarchical mixture models. Homocysteine level response to multivitamin in cerebral infarction 760 European ancestry treated cases, 773 European ancestry untreated cases NA Illumina [774670] 0 homocysteine measurement, response to vitamin http://www.ebi.ac.uk/efo/EFO_0004578, http://purl.obolibrary.org/obo/GO_0033273 GCST007366 Genome-wide genotyping array 1533 2021-07-27 33469137 Crawford AA 2021-01-20 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/33469137 Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease. Plasma cortisol levels (morning) 25,314 European ancestry individuals NA Affymetrix, Illumina [8452427] (imputed) 4 cortisol measurement http://www.ebi.ac.uk/efo/EFO_0005843 GCST012087 Genome-wide genotyping array 25314 2019-01-21 30326835 Li Z 2018-10-16 BMC Genomics www.ncbi.nlm.nih.gov/pubmed/30326835 Genetic variants in nuclear DNA along with environmental factors modify mitochondrial DNA copy number: a population-based exome-wide association study. Mitochondrial DNA levels 301 Chinese ancestry individuals NA Illumina [238927] 1 mitochondrial DNA measurement http://www.ebi.ac.uk/efo/EFO_0006312 GCST006936 Exome genotyping array [Exome array] 301 2021-07-30 33104735 Lundtoft C 2020-10-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33104735 Function of multiple sclerosis-protective HLA class I alleles revealed by genome-wide protein-quantitative trait loci mapping of interferon signalling. interferon-related traits 303 European ancestry individuals NA Illumina [5084123] (imputed) 326 cytokine measurement http://www.ebi.ac.uk/efo/EFO_0004873 GCST012156 Genome-wide genotyping array 303 2020-11-13 32887889 Rashkin SR 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887889 Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Breast cancer 17,881 European ancestry cases, 410,350 European ancestry controls NA Affymetrix [7846216] (imputed) 77 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST90011804 Genome-wide genotyping array 428231 2020-11-13 32887889 Rashkin SR 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887889 Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Testicular cancer 713 European ancestry cases, 359,825 European ancestry controls NA Affymetrix [7846216] (imputed) 16 testicular carcinoma http://www.ebi.ac.uk/efo/EFO_0005088 GCST90011805 Genome-wide genotyping array 360538 2020-11-13 32887889 Rashkin SR 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887889 Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Oral cavity and pharyngeal cancer 1,223 European ancestry cases, 410,350 European ancestry controls NA Affymetrix [7846216] (imputed) 10 oropharynx cancer http://www.ebi.ac.uk/efo/EFO_1001931 GCST90011806 Genome-wide genotyping array 411573 2020-11-13 32887889 Rashkin SR 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887889 Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Esophageal or stomach cancer 1,091 European ancestry cases, 410,350 European ancestry controls NA Affymetrix [7846216] (imputed) 11 esophageal carcinoma, gastric carcinoma http://www.ebi.ac.uk/efo/EFO_0002916, http://www.ebi.ac.uk/efo/EFO_0000178 GCST90011807 Genome-wide genotyping array 411441 2020-11-13 32887889 Rashkin SR 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887889 Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Prostate cancer 10,792 European ancestry cases, 410,350 European ancestry controls NA Affymetrix [7846216] (imputed) 65 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST90011808 Genome-wide genotyping array 421142 2020-11-13 32887889 Rashkin SR 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887889 Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Melanoma 6,777 European ancestry cases, 410,350 European ancestry controls NA Affymetrix [7846216] (imputed) 38 melanoma http://www.ebi.ac.uk/efo/EFO_0000756 GCST90011809 Genome-wide genotyping array 417127 2020-11-13 32887889 Rashkin SR 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887889 Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Rectal cancer 2,091 European ancestry cases, 410,350 European ancestry controls NA Affymetrix [7846216] (imputed) 12 rectum cancer http://www.ebi.ac.uk/efo/EFO_1000657 GCST90011810 Genome-wide genotyping array 412441 2020-11-13 32887889 Rashkin SR 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887889 Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Colon cancer 3,793 European ancestry cases, 410,350 European ancestry controls NA Affymetrix [7846216] (imputed) 13 colon carcinoma http://www.ebi.ac.uk/efo/EFO_1001950 GCST90011811 Genome-wide genotyping array 414143 2020-11-13 32887889 Rashkin SR 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887889 Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Lung cancer 2,485 European ancestry cases, 410,350 European ancestry controls NA Affymetrix [7846216] (imputed) 8 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST90011812 Genome-wide genotyping array 412835 2020-11-13 32887889 Rashkin SR 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887889 Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Thyroid cancer 762 European ancestry cases, 410,350 European ancestry controls NA Affymetrix [7846216] (imputed) 14 thyroid carcinoma http://www.ebi.ac.uk/efo/EFO_0002892 GCST90011813 Genome-wide genotyping array 411112 2020-11-13 32887889 Rashkin SR 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887889 Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Lymphocytic leukemia 852 European ancestry cases, 410,350 European ancestry controls NA Affymetrix [7846216] (imputed) 24 lymphoid leukemia http://www.ebi.ac.uk/efo/EFO_0004289 GCST90011814 Genome-wide genotyping array 411202 2020-11-13 32887889 Rashkin SR 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887889 Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Pancreatic cancer 663 European ancestry cases, 410,350 European ancestry controls NA Affymetrix [7846216] (imputed) 12 pancreatic carcinoma http://www.ebi.ac.uk/efo/EFO_0002618 GCST90011815 Genome-wide genotyping array 411013 2020-11-13 32887889 Rashkin SR 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887889 Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Cervical cancer 6,563 European ancestry cases, 410,350 European ancestry controls NA Affymetrix [7846216] (imputed) 11 cervical carcinoma http://www.ebi.ac.uk/efo/EFO_0001061 GCST90011816 Genome-wide genotyping array 416913 2020-11-13 32887889 Rashkin SR 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887889 Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Bladder cancer 2,242 European ancestry cases, 410,350 European ancestry controls NA Affymetrix [7846216] (imputed) 10 bladder carcinoma http://www.ebi.ac.uk/efo/EFO_0000292 GCST90011817 Genome-wide genotyping array 412592 2020-11-13 32887889 Rashkin SR 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887889 Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Kidney cancer 1,338 European ancestry cases, 410,350 European ancestry controls NA Affymetrix [7846216] (imputed) 10 kidney cancer http://purl.obolibrary.org/obo/MONDO_0002367 GCST90011818 Genome-wide genotyping array 411688 2020-11-13 32887889 Rashkin SR 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887889 Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Non-Hodgkin's lymphoma 2,400 European ancestry cases, 410,350 European ancestry controls NA Affymetrix [7846216] (imputed) 15 non-Hodgkins lymphoma http://www.ebi.ac.uk/efo/EFO_0005952 GCST90011819 Genome-wide genotyping array 412750 2020-11-13 32887889 Rashkin SR 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887889 Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Endometrial cancer 2,037 European ancestry cases, 410,350 European ancestry controls NA Affymetrix [7846216] (imputed) 7 endometrial carcinoma http://www.ebi.ac.uk/efo/EFO_1001512 GCST90011820 Genome-wide genotyping array 412387 2020-11-13 32887889 Rashkin SR 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887889 Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Ovarian cancer 1,259 European ancestry cases, 410,350 European ancestry controls NA Affymetrix [7846216] (imputed) 1 ovarian carcinoma http://www.ebi.ac.uk/efo/EFO_0001075 GCST90011821 Genome-wide genotyping array 411609 2020-11-13 32887889 Rashkin SR 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887889 Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Cancer (pleiotropy) 64,962 European ancestry cases, 410,350 European ancestry controls NA Affymetrix [7846216] (imputed) 137 cancer http://www.ebi.ac.uk/efo/EFO_0000311 GCST90011822 Genome-wide genotyping array 475312 2020-11-13 32887889 Rashkin SR 2020-09-04 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32887889 Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Cancer (pleiotropy)(bidirectional) 64,962 European ancestry cases, 410,350 European ancestry controls NA Affymetrix [7846216] (imputed) 21 cancer http://www.ebi.ac.uk/efo/EFO_0000311 GCST90011823 Genome-wide genotyping array 475312 2018-12-14 30323354 Lee JY 2018-10-15 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30323354 BRCA1/2-negative, high-risk breast cancers (BRCAX) for Asian women: genetic susceptibility loci and their potential impacts. BRCA1/2-negative high-risk breast cancer 1,469 Korean ancestry cases, 5,979 Korean ancestry controls NA Affymetrix, Illumina [3378933] (imputed) 19 BRCAX breast cancer http://www.ebi.ac.uk/efo/EFO_0009443 GCST006719 Genome-wide genotyping array 7448 2018-12-14 30336701 Sanchez-Roige S 2018-10-19 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/30336701 Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts. Alcohol use disorder (total score) 141,932 European ancestry individuals NA NR [16213998] 15 alcohol use disorder measurement http://www.ebi.ac.uk/efo/EFO_0009458 GCST006716 Genome-wide genotyping array 141932 2018-12-14 30336701 Sanchez-Roige S 2018-10-19 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/30336701 Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts. Alcohol use disorder (consumption score) 121,604 British ancestry individuals NA NR [16213998] 9 alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0007878 GCST006718 Genome-wide genotyping array 121604 2018-12-14 30336701 Sanchez-Roige S 2018-10-19 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/30336701 Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts. Alcohol use disorder (dependence and problematic use scores) 121,604 British ancestry individuals NA NR [16213998] 5 alcohol dependence measurement http://www.ebi.ac.uk/efo/EFO_0007835 GCST006717 Genome-wide genotyping array 121604 2019-12-05 23696881 Wood AR 2013-05-16 PLoS One www.ncbi.nlm.nih.gov/pubmed/23696881 Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation. Blood protein levels up to 1,209 European ancestry individuals NA Illumina [up to 10879115] (imputed) 15 protein measurement http://www.ebi.ac.uk/efo/EFO_0004747 GCST009159 Genome-wide genotyping array 1209 2019-12-05 23696881 Wood AR 2013-05-16 PLoS One www.ncbi.nlm.nih.gov/pubmed/23696881 Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation. Homocysteine levels 1,208 European ancestry individuals NA Illumina [up to 10879115] (imputed) 1 homocysteine measurement http://www.ebi.ac.uk/efo/EFO_0004578 GCST009171 Genome-wide genotyping array 1208 2019-12-05 23696881 Wood AR 2013-05-16 PLoS One www.ncbi.nlm.nih.gov/pubmed/23696881 Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation. Carotenoid levels up to 1,200 European ancestry individuals NA Illumina [up to 10879115] (imputed) 3 carotenoid measurement http://www.ebi.ac.uk/efo/EFO_0004737 GCST009160 Genome-wide genotyping array 1200 2019-12-05 23696881 Wood AR 2013-05-16 PLoS One www.ncbi.nlm.nih.gov/pubmed/23696881 Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation. Diabetes biomarker traits up to 1,209 European ancestry individuals NA Illumina [up to 10879115] (imputed) 0 diabetes mellitus biomarker http://www.ebi.ac.uk/efo/EFO_0006842 GCST009161 Genome-wide genotyping array 1209 2019-12-05 23696881 Wood AR 2013-05-16 PLoS One www.ncbi.nlm.nih.gov/pubmed/23696881 Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation. Hematology traits up to 1,209 European ancestry individuals NA Illumina [up to 10879115] (imputed) 0 hematological measurement http://www.ebi.ac.uk/efo/EFO_0004503 GCST009162 Genome-wide genotyping array 1209 2019-12-05 23696881 Wood AR 2013-05-16 PLoS One www.ncbi.nlm.nih.gov/pubmed/23696881 Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation. Hormone measurements up to 1,200 European ancestry individuals NA Illumina [up to 10879115] (imputed) 3 hormone measurement http://www.ebi.ac.uk/efo/EFO_0004730 GCST009163 Genome-wide genotyping array 1200 2019-12-05 23696881 Wood AR 2013-05-16 PLoS One www.ncbi.nlm.nih.gov/pubmed/23696881 Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation. Circulating inorganic ion levels up to 1,209 European ancestry individuals NA Illumina [up to 10879115] (imputed) 0 inorganic ion measurement http://www.ebi.ac.uk/efo/EFO_0010243 GCST009164 Genome-wide genotyping array 1209 2019-12-05 23696881 Wood AR 2013-05-16 PLoS One www.ncbi.nlm.nih.gov/pubmed/23696881 Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation. Lipid or lipoprotein levels up to 1,206 European ancestry individuals NA Illumina [up to 10879115] (imputed) 6 lipid or lipoprotein measurement http://www.ebi.ac.uk/efo/EFO_0005105 GCST009165 Genome-wide genotyping array 1206 2019-12-05 23696881 Wood AR 2013-05-16 PLoS One www.ncbi.nlm.nih.gov/pubmed/23696881 Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation. Renal system biomarkers up to 1,209 European ancestry individuals NA Illumina [up to 10879115] (imputed) 0 renal system measurement http://www.ebi.ac.uk/efo/EFO_0004742 GCST009166 Genome-wide genotyping array 1209 2019-12-05 23696881 Wood AR 2013-05-16 PLoS One www.ncbi.nlm.nih.gov/pubmed/23696881 Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation. Vitamin levels up to 1,200 European ancestry individuals NA Illumina [up to 10879115] (imputed) 3 vitamin measurement http://www.ebi.ac.uk/efo/EFO_0004729 GCST009167 Genome-wide genotyping array 1200 2019-12-05 23696881 Wood AR 2013-05-16 PLoS One www.ncbi.nlm.nih.gov/pubmed/23696881 Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation. Tumor necrosis factor alpha levels 1,167 European ancestry individuals 708 individuals Illumina [up to 10879115] (imputed) 0 tumor necrosis factor-alpha measurement http://www.ebi.ac.uk/efo/EFO_0004684 GCST009168 Genome-wide genotyping array 1167 2019-12-05 23696881 Wood AR 2013-05-16 PLoS One www.ncbi.nlm.nih.gov/pubmed/23696881 Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation. Vitamin B12 levels 1,175 European ancestry individuals 2,083 individuals Illumina [up to 10879115] (imputed) 0 vitamin B12 measurement http://www.ebi.ac.uk/efo/EFO_0004620 GCST009169 Genome-wide genotyping array 1175 2019-12-05 23696881 Wood AR 2013-05-16 PLoS One www.ncbi.nlm.nih.gov/pubmed/23696881 Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation. Chloride levels 1,206 European ancestry individuals 4,068 individuals Illumina [up to 10879115] (imputed) 0 chloride measurement http://www.ebi.ac.uk/efo/EFO_0009284 GCST009170 Genome-wide genotyping array 1206 2019-01-08 30172742 Hu Y 2018-08-30 Bone www.ncbi.nlm.nih.gov/pubmed/30172742 Identification of novel variants associated with osteoporosis, type 2 diabetes and potentially pleiotropic loci using pleiotropic cFDR method. Femoral neck bone mineral density or type 2 diabetes (pleiotropy) 53,236 European ancestry individuals with bone mineral density data, 26,676 European ancestry type 2 diabetes cases, 132,532 European ancestry controls NA NR [132735] 0 type II diabetes mellitus, femoral neck bone mineral density http://www.ebi.ac.uk/efo/EFO_0001360, http://www.ebi.ac.uk/efo/EFO_0007785 GCST006861 Genome-wide genotyping array 212446 2018-10-17 30181573 Jing J 2018-09-04 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30181573 Genetics of serum urate concentrations and gout in a high-risk population, patients with chronic kidney disease. Serum urate levels in chronic kidney disease 4,941 European ancestry cases NA Illumina [9281895] (imputed) 7 urate measurement http://www.ebi.ac.uk/efo/EFO_0004531 GCST006426 Genome-wide genotyping array 4941 2018-10-17 30181573 Jing J 2018-09-04 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30181573 Genetics of serum urate concentrations and gout in a high-risk population, patients with chronic kidney disease. Gout in chronic kidney disease 1,217 European ancestry cases, 3,724 European ancestry controls NA Illumina [9281895] (imputed) 2 gout http://www.ebi.ac.uk/efo/EFO_0004274 GCST006425 Genome-wide genotyping array 4941 2018-11-01 30185882 Zeiger AM 2018-09-05 Sci Rep www.ncbi.nlm.nih.gov/pubmed/30185882 Genetic Determinants of Telomere Length in African American Youth. Telomere length 492 African American children and adolescents NA Affymetrix [7519176] (imputed) 15 telomere length http://www.ebi.ac.uk/efo/EFO_0004505 GCST006485 Genome-wide genotyping array 492 2021-02-03 33398198 Conti DV 2021-01-04 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33398198 Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Prostate cancer 85,554 European ancestry cases, 10,368 African ancestry cases, 8,611 East Asian ancestry cases, 2,714 Hispanic cases, 91,972 European ancestry controls, 10,986 African ancestry controls, 18,809 East Asian ancestry controls, 5,239 Hispanic controls NA Affymetrix, Illumina [29235255] (imputed) 264 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST011049 Genome-wide genotyping array 234253 2021-02-03 33398198 Conti DV 2021-01-04 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33398198 Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Prostate cancer 85,554 European ancestry cases, 91,972 European ancestry controls 6,852 European ancestry cases, 193,117 European ancestry controls Affymetrix, Illumina [20400945] (imputed) 64 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST011048 Genome-wide genotyping array 177526 2021-02-03 33398198 Conti DV 2021-01-04 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33398198 Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Prostate cancer 10,368 African ancestry cases, 10,986 African ancestry controls NA Affymetrix, Illumina [18877980] (imputed) 20 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST011047 Genome-wide genotyping array 21354 2021-02-03 33398198 Conti DV 2021-01-04 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33398198 Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Prostate cancer 8,611 East Asian ancestry cases, 18,809 East Asian ancestry controls NA Affymetrix, Illumina [10186136] (imputed) 48 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST011046 Genome-wide genotyping array 27420 2021-02-03 33398198 Conti DV 2021-01-04 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33398198 Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Prostate cancer 2,714 Hispanic cases, 5,239 Hispanic controls NA Affymetrix, Illumina [11334207] (imputed) 4 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST011045 Genome-wide genotyping array 7953 2021-02-08 33239696 Steinthorsdottir V 2020-11-25 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33239696 Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women. Preeclampsia (fetal genotype effect) 2,145 Central Asian ancestry cases, 2,027 Central Asian ancestry controls, 4,630 European ancestry cases, 373,345 European ancestry controls 452 Kazakh ancestry cases, 361 Kazakh ancestry controls, 580 European ancestry cases, 760 European ancestry controls Illumina [12130433] (imputed) 4 preeclampsia, fetal genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0000668, http://www.ebi.ac.uk/efo/EFO_0007959 GCST90013475 Genome-wide genotyping array 382147 2021-02-08 33239696 Steinthorsdottir V 2020-11-25 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33239696 Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women. Preeclampsia (fetal genotype effect) 2,145 Central Asian ancestry cases, 2,027 Central Asian ancestry controls 452 Kazakh ancestry cases, 361 Kazakh ancestry controls Illumina [at least 12130433] (imputed) 0 preeclampsia, fetal genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0000668, http://www.ebi.ac.uk/efo/EFO_0007959 GCST90013476 Genome-wide genotyping array 4172 2021-02-08 33239696 Steinthorsdottir V 2020-11-25 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33239696 Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women. Preeclampsia (fetal genotype effect) 4,630 European ancestry cases, 373,345 European ancestry controls 580 European ancestry cases, 760 European ancestry controls Illumina [at least 12130433] (imputed) 0 preeclampsia, fetal genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0000668, http://www.ebi.ac.uk/efo/EFO_0007959 GCST90013477 Genome-wide genotyping array 377975 2021-02-08 33239696 Steinthorsdottir V 2020-11-25 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33239696 Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women. Preeclampsia (maternal genotype effect) 2,296 Central Asian ancestry cases, 2,059 Central Asian ancestry controls, 7,219 European ancestry cases, 155,660 European ancestry controls 592 Kazakh ancestry cases, 361 Kazakh ancestry controls, 2,043 European ancestry cases, 6,018 European ancestry controls Illumina [11796347] (imputed) 12 preeclampsia, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0000668, http://www.ebi.ac.uk/efo/EFO_0005939 GCST90013478 Genome-wide genotyping array 167234 2021-02-08 33239696 Steinthorsdottir V 2020-11-25 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33239696 Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women. Preeclampsia (maternal genotype effect) 2,296 Central Asian ancestry cases, 2,059 Central Asian ancestry controls 592 Kazakh ancestry cases, 361 Kazakh ancestry controls Illumina [at least 11796347] (imputed) 0 preeclampsia, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0000668, http://www.ebi.ac.uk/efo/EFO_0005939 GCST90013479 Genome-wide genotyping array 4355 2021-02-08 33239696 Steinthorsdottir V 2020-11-25 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33239696 Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women. Preeclampsia (maternal genotype effect) 7,219 European ancestry cases, 155,660 European ancestry controls 2,043 European ancestry cases, 6,018 European ancestry controls Illumina [at least 11796347] (imputed) 0 preeclampsia, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0000668, http://www.ebi.ac.uk/efo/EFO_0005939 GCST90013480 Genome-wide genotyping array 162879 2021-07-01 33381925 Buchanan VL 2020-12-30 Pediatr Obes www.ncbi.nlm.nih.gov/pubmed/33381925 Genome-wide association study identifying novel variant for fasting insulin and allelic heterogeneity in known glycemic loci in Chilean adolescents: The Santiago Longitudinal Study. Fasting insulin 543 Chilean individuals 18,637 European ancestry individuals, 14,270 Hispanic individuals, 7,683 African ancestry individuals, 1,900 Asian ancestry individuals, 1,398 Native Hawaiian ancestry individuals, 392 individuals Illumina [NR] (imputed) 0 fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004466 GCST011982 Genome-wide genotyping array 543 2021-07-01 33381925 Buchanan VL 2020-12-30 Pediatr Obes www.ncbi.nlm.nih.gov/pubmed/33381925 Genome-wide association study identifying novel variant for fasting insulin and allelic heterogeneity in known glycemic loci in Chilean adolescents: The Santiago Longitudinal Study. Homeostasis model assessment of insulin resistance 543 Chilean individuals NA Illumina [NR] (imputed) 15 HOMA-IR http://www.ebi.ac.uk/efo/EFO_0004501 GCST011981 Genome-wide genotyping array 543 2021-07-01 33381925 Buchanan VL 2020-12-30 Pediatr Obes www.ncbi.nlm.nih.gov/pubmed/33381925 Genome-wide association study identifying novel variant for fasting insulin and allelic heterogeneity in known glycemic loci in Chilean adolescents: The Santiago Longitudinal Study. Fasting glucose 543 Chilean individuals NA Illumina [NR] (imputed) 24 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST011983 Genome-wide genotyping array 543 2020-06-04 29514802 Leonard D 2018-03-07 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/29514802 Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis. Cardiovascular disease in systemic lupus erythematosus 133 European ancestry cases, 681 Europen ancestry controls 84 European ancestry cases, 959 European ancestry controls Illumina [137213] 0 cardiovascular disease http://www.ebi.ac.uk/efo/EFO_0000319 GCST010044 Targeted genotyping array [ImmunoChip] 814 2020-04-23 31001917 Grant DJ 2019-04-18 Cancer Med www.ncbi.nlm.nih.gov/pubmed/31001917 Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women. Epithelial ovarian cancer 755 African American cases, 1,235 African American controls NA Illumina [471780] 1 Malignant epithelial tumor of ovary http://www.orpha.net/ORDO/Orphanet_398934 GCST009896 Targeted genotyping array [Oncoarray] 1990 2020-08-18 32247823 Parisinos CA 2020-04-02 J Hepatol www.ncbi.nlm.nih.gov/pubmed/32247823 Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis. Liver fat content (MRI proton density fat fraction measure) 14,440 European ancestry individuals NA Affymetrix [~ 12000000] (imputed) 4 liver fat measurement, liver disease biomarker http://www.ebi.ac.uk/efo/EFO_0010821, http://www.ebi.ac.uk/efo/EFO_0006845 GCST010417 Genome-wide genotyping array 14440 2020-08-18 32247823 Parisinos CA 2020-04-02 J Hepatol www.ncbi.nlm.nih.gov/pubmed/32247823 Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis. Liver fibrosis and steatohepatitis severity (MRI cT1 measure) 14,440 European ancestry individuals NA Affymetrix [~ 12000000] (imputed) 7 liver fat measurement, liver disease biomarker http://www.ebi.ac.uk/efo/EFO_0010821, http://www.ebi.ac.uk/efo/EFO_0006845 GCST010418 Genome-wide genotyping array 14440 2020-09-10 32747698 Matoba N 2020-08-03 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32747698 Common genetic risk variants identified in the SPARK cohort support DDHD2 as a candidate risk gene for autism. Autism spectrum disorder 22,916 European ancestry cases, 37 African ancestry cases, 83 East Asian ancestry cases, 1,567 cases, 32,504 European ancestry controls, 37 African ancestry controls, 83 East Asian ancestry controls, 1,567 controls NA Illumina [up to 8992756] (imputed) 0 autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0003756 GCST010513 Genome-wide genotyping array 58794 2020-09-10 32747698 Matoba N 2020-08-03 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32747698 Common genetic risk variants identified in the SPARK cohort support DDHD2 as a candidate risk gene for autism. Autism spectrum disorder 4,535 European ancestry cases, 37 African ancestry cases, 83 East Asian ancestry cases, 1,567 cases, 4,535 European ancestry controls, 37 African ancestry controls, 83 East Asian ancestry controls, 1,567 controls NA Illumina [8992756] (imputed) 17 autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0003756 GCST010515 Genome-wide genotyping array 12444 2020-09-10 32747698 Matoba N 2020-08-03 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32747698 Common genetic risk variants identified in the SPARK cohort support DDHD2 as a candidate risk gene for autism. Autism spectrum disorder 22,916 European ancestry cases, 32,504 European ancestry controls NA Illumina [up to 8992756] (imputed) 5 autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0003756 GCST010514 Genome-wide genotyping array 55420 2021-03-19 32755526 D'Urso S 2020-08-05 Twin Res Hum Genet www.ncbi.nlm.nih.gov/pubmed/32755526 Septic Shock: A Genomewide Association Study and Polygenic Risk Score Analysis. Septic shock (28-day mortality) 90 European ancestry cases, 403 European ancestry controls NA Illumina [7590211] (imputed) 1 septic shock http://www.ebi.ac.uk/efo/EFO_0006834 GCST011301 Genome-wide genotyping array 493 2021-03-19 32755526 D'Urso S 2020-08-05 Twin Res Hum Genet www.ncbi.nlm.nih.gov/pubmed/32755526 Septic Shock: A Genomewide Association Study and Polygenic Risk Score Analysis. Septic shock (90-day mortality) 112 European ancestry cases, 381 European ancestry controls NA Illumina [7590211] (imputed) 0 septic shock http://www.ebi.ac.uk/efo/EFO_0006834 GCST011302 Genome-wide genotyping array 493 2021-03-19 32755526 D'Urso S 2020-08-05 Twin Res Hum Genet www.ncbi.nlm.nih.gov/pubmed/32755526 Septic Shock: A Genomewide Association Study and Polygenic Risk Score Analysis. Septic shock resolution 459 European ancestry cases, 34 European ancestry controls NA Illumina [7590211] (imputed) 3 septic shock http://www.ebi.ac.uk/efo/EFO_0006834 GCST011304 Genome-wide genotyping array 493 2021-03-19 32755526 D'Urso S 2020-08-05 Twin Res Hum Genet www.ncbi.nlm.nih.gov/pubmed/32755526 Septic Shock: A Genomewide Association Study and Polygenic Risk Score Analysis. Septic shock 493 European ancestry cases, 2,442 European ancestry controls NA Illumina [7567032] (imputed) 1 septic shock http://www.ebi.ac.uk/efo/EFO_0006834 GCST011303 Genome-wide genotyping array 2935 2021-05-24 32753590 Park B 2020-08-04 Sci Rep www.ncbi.nlm.nih.gov/pubmed/32753590 Effect of 6p21 region on lung function is modified by smoking: a genome-wide interaction study. FEV1/FVC ratio x pack-years of smoking interaction (2df test) 1,140 Korean ancestry former smokers, 1,565 Korean ancestry current smokers, 4,768 Korean ancestry controls 65 Korean ancestry former smokers, 592 Korean ancestry current smokers, 2,889 Korean ancestry controls Affymetrix [3351033] (imputed) 0 pack-years measurement, FEV/FEC ratio http://www.ebi.ac.uk/efo/EFO_0006526, http://www.ebi.ac.uk/efo/EFO_0004713 GCST011718 Genome-wide genotyping array 7473 2021-02-09 32678081 Timmers PRHJ 2020-07-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32678081 Multivariate genomic scan implicates novel loci and haem metabolism in human ageing. Aging traits (healthspan, parental lifespan or longevity) (multivariate analysis) at least 837,415 European ancestry individuals NA NR [7320282] 24 longevity, healthspan, parental longevity http://www.ebi.ac.uk/efo/EFO_0004300, http://www.ebi.ac.uk/efo/EFO_0009762, http://www.ebi.ac.uk/efo/EFO_0007796 GCST011100 Genome-wide genotyping array 837415 2021-05-07 33426524 Ramanan VK 2020-09-26 Brain Commun www.ncbi.nlm.nih.gov/pubmed/33426524 Variants in PPP2R2B and IGF2BP3 are associated with higher tau deposition. Tau burden 754 European ancestry individuals NA Illumina [6417232] (imputed) 12 t-tau measurement http://www.ebi.ac.uk/efo/EFO_0004760 GCST011624 Genome-wide genotyping array 754 2019-06-25 30804565 Jansen PR 2019-02-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30804565 Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways. Insomnia 651,923 European ancestry males, 679,087 European ancestry females NA Affymetrix, Illumina [NR] (imputed) 364 insomnia measurement http://www.ebi.ac.uk/efo/EFO_0007876 GCST007988 Genome-wide genotyping array 1331010 2019-06-25 30804565 Jansen PR 2019-02-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30804565 Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways. Morningness 434,835 European ancestry individuals NA Affymetrix, Illumina [11597492] (imputed) 274 chronotype measurement http://www.ebi.ac.uk/efo/EFO_0008328 GCST007983 Genome-wide genotyping array 434835 2019-06-25 30804565 Jansen PR 2019-02-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30804565 Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways. Sleep duration 384,317 European ancestry individuals NA Affymetrix, Illumina [10862567] (imputed) 53 sleep duration http://www.ebi.ac.uk/efo/EFO_0005271 GCST007982 Genome-wide genotyping array 384317 2019-06-25 30804565 Jansen PR 2019-02-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30804565 Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways. Ease of getting up in the morning 385,949 European ancestry individuals NA Affymetrix, Illumina [10862568] (imputed) 70 chronotype measurement http://www.ebi.ac.uk/efo/EFO_0008328 GCST007986 Genome-wide genotyping array 385949 2019-06-25 30804565 Jansen PR 2019-02-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30804565 Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways. Daytime nap 386,577 European ancestry individuals NA Affymetrix, Illumina [10858887] (imputed) 7 daytime rest measurement http://www.ebi.ac.uk/efo/EFO_0007828 GCST007987 Genome-wide genotyping array 386577 2019-06-25 30804565 Jansen PR 2019-02-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30804565 Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways. Daytime sleepiness 386,548 European ancestry individuals NA Affymetrix, Illumina [10820725] (imputed) 1 excessive daytime sleepiness measurement http://www.ebi.ac.uk/efo/EFO_0007875 GCST007984 Genome-wide genotyping array 386548 2019-06-25 30804565 Jansen PR 2019-02-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30804565 Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways. Snoring 359,916 European ancestry individuals NA Affymetrix, Illumina [10862568] (imputed) 42 snoring measurement http://www.ebi.ac.uk/efo/EFO_0008341 GCST007985 Genome-wide genotyping array 359916 2021-03-05 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Lysine levels 996 European ancestry individuals NA Illumina [283704] 1 lysine measurement http://www.ebi.ac.uk/efo/EFO_0005002 GCST90013564 Genome-wide genotyping array 996 2021-03-05 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. N-acetyl neuraminic acid levels 996 European ancestry individuals NA Illumina [283704] 2 n-acetyl neuraminic acid measurement http://www.ebi.ac.uk/efo/EFO_0010993 GCST90013565 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. N-methyl-2-pyridone-5-carboxamide levels 996 European ancestry individuals NA Illumina [283704] 0 n-methyl-2-pyridone-5-carboxamide measurement http://www.ebi.ac.uk/efo/EFO_0010994 GCST90013566 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. N-methylnicotinic acid levels 996 European ancestry individuals NA Illumina [283704] 0 n-methylnicotinic acid measurement http://www.ebi.ac.uk/efo/EFO_0010995 GCST90013567 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. N-methylpicolinic acid levels 996 European ancestry individuals NA Illumina [283704] 0 n-methylpicolinic acid measurement http://www.ebi.ac.uk/efo/EFO_0010996 GCST90013568 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. N1-methyl-nicotinamide levels 996 European ancestry individuals NA Illumina [283704] 0 n1-methyl-nicotinamide measurement http://www.ebi.ac.uk/efo/EFO_0010997 GCST90013569 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. P-cresol sulfate levels 996 European ancestry individuals NA Illumina [283704] 0 p-cresol sulfate measurement http://www.ebi.ac.uk/efo/EFO_0010998 GCST90013570 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. P-hydroxyphenylacetate levels 996 European ancestry individuals NA Illumina [283704] 0 p-hydroxyphenylacetate measurement http://www.ebi.ac.uk/efo/EFO_0010999 GCST90013571 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Pantothenic acid levels 996 European ancestry individuals NA Illumina [283704] 0 pantothenic acid mesurement http://www.ebi.ac.uk/efo/EFO_0010519 GCST90013572 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Proline betaine levels 996 European ancestry individuals NA Illumina [283704] 0 proline betaine measurement http://www.ebi.ac.uk/efo/EFO_0011000 GCST90013573 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Scyllo-inositol levels 996 European ancestry individuals NA Illumina [283704] 0 scyllo-inositol measurement http://www.ebi.ac.uk/efo/EFO_0011001 GCST90013574 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Succinate levels 996 European ancestry individuals NA Illumina [283704] 0 succinate measurement http://www.ebi.ac.uk/efo/EFO_0011002 GCST90013575 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Sucrose levels 996 European ancestry individuals NA Illumina [283704] 0 sucrose measurement http://www.ebi.ac.uk/efo/EFO_0010535 GCST90013576 Genome-wide genotyping array 996 2021-03-05 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Taurine levels 996 European ancestry individuals NA Illumina [283704] 1 taurine measurement http://www.ebi.ac.uk/efo/EFO_0010536 GCST90013577 Genome-wide genotyping array 996 2021-03-05 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Trimethylamine levels 996 European ancestry individuals NA Illumina [283704] 1 trimethylamine measurement http://www.ebi.ac.uk/efo/EFO_0011003 GCST90013578 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Trimethylamine oxide levels 996 European ancestry individuals NA Illumina [283704] 0 trimethylamine oxide measurement http://www.ebi.ac.uk/efo/EFO_0011004 GCST90013579 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Tyrosine levels 996 European ancestry individuals NA Illumina [283704] 0 tyrosine measurement http://www.ebi.ac.uk/efo/EFO_0005058 GCST90013580 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Urea levels 996 European ancestry individuals NA Illumina [283704] 0 urea measurement http://www.ebi.ac.uk/efo/EFO_0011005 GCST90013581 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Valine levels 996 European ancestry individuals NA Illumina [283704] 0 valine measurement http://www.ebi.ac.uk/efo/EFO_0009792 GCST90013582 Genome-wide genotyping array 996 2021-02-18 33287642 Said MA 2020-12-08 J Am Heart Assoc www.ncbi.nlm.nih.gov/pubmed/33287642 Associations of Observational and Genetically Determined Caffeine Intake With Coronary Artery Disease and Diabetes Mellitus. Caffeine consumption from coffee 373,522 European ancestry individuals NA Affymetrix [19400838] (imputed) 24 coffee consumption measurement http://www.ebi.ac.uk/efo/EFO_0006781 GCST011125 Genome-wide genotyping array 373522 2021-02-18 33287642 Said MA 2020-12-08 J Am Heart Assoc www.ncbi.nlm.nih.gov/pubmed/33287642 Associations of Observational and Genetically Determined Caffeine Intake With Coronary Artery Disease and Diabetes Mellitus. Caffeine consumption from tea 395,866 European ancestry individuals NA Affymetrix [19400838] (imputed) 24 tea consumption measurement http://www.ebi.ac.uk/efo/EFO_0010091 GCST011124 Genome-wide genotyping array 395866 2021-02-18 33287642 Said MA 2020-12-08 J Am Heart Assoc www.ncbi.nlm.nih.gov/pubmed/33287642 Associations of Observational and Genetically Determined Caffeine Intake With Coronary Artery Disease and Diabetes Mellitus. Caffeine consumption from coffee or tea 362,316 European ancestry individuals NA Affymetrix [19400838] (imputed) 37 coffee consumption measurement, tea consumption measurement http://www.ebi.ac.uk/efo/EFO_0006781, http://www.ebi.ac.uk/efo/EFO_0010091 GCST011126 Genome-wide genotyping array 362316 2021-02-17 33370439 Dusingize JC 2020-12-28 Int J Epidemiol www.ncbi.nlm.nih.gov/pubmed/33370439 Genetically determined risk of keratinocyte carcinoma and risk of other cancers. Keratinocyte cancer (MTAG) 669,243 European ancestry individuals NA NR [NR] 0 keratinocyte carcinoma http://www.ebi.ac.uk/efo/EFO_0010176 GCST011120 Genome-wide genotyping array 669243 2021-02-17 33370439 Dusingize JC 2020-12-28 Int J Epidemiol www.ncbi.nlm.nih.gov/pubmed/33370439 Genetically determined risk of keratinocyte carcinoma and risk of other cancers. Keratinocyte cancer (MTAG) 323,345 European ancestry individuals NA NR [NR] 0 keratinocyte carcinoma http://www.ebi.ac.uk/efo/EFO_0010176 GCST011121 Genome-wide genotyping array 323345 2020-08-25 32427856 Ahmad S 2020-05-19 Sci Rep www.ncbi.nlm.nih.gov/pubmed/32427856 CDH6 and HAGH protein levels in plasma associate with Alzheimer's disease in APOE ε4 carriers. HAGH protein levels in plasma 281 individuals NA Illumina [NR] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST010458 Genome-wide genotyping array 281 2020-08-25 32427856 Ahmad S 2020-05-19 Sci Rep www.ncbi.nlm.nih.gov/pubmed/32427856 CDH6 and HAGH protein levels in plasma associate with Alzheimer's disease in APOE ε4 carriers. CDH6 protein levels in plasma 281 individuals NA Illumina [NR] (imputed) 1 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST010459 Genome-wide genotyping array 281 2021-06-22 33293549 Sargurupremraj M 2020-12-08 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33293549 Cerebral small vessel disease genomics and its implications across the lifespan. White matter hyperintensity volume x hypertension interaction (2df) 46,055 European ancestry individuals NA Affymetrix, Illumina [9900000] (imputed) 26 hypertension, white matter hyperintensity measurement http://www.ebi.ac.uk/efo/EFO_0000537, http://www.ebi.ac.uk/efo/EFO_0005665 GCST011953 Genome-wide genotyping array 46055 2021-06-22 33293549 Sargurupremraj M 2020-12-08 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33293549 Cerebral small vessel disease genomics and its implications across the lifespan. White matter hyperintensity volume x hypertension interaction (2df) 46,055 European ancestry individuals, 2,469 African American individuals NA Affymetrix, Illumina [9900000] (imputed) 26 hypertension, white matter hyperintensity measurement http://www.ebi.ac.uk/efo/EFO_0000537, http://www.ebi.ac.uk/efo/EFO_0005665 GCST011952 Genome-wide genotyping array 48524 2021-06-22 33293549 Sargurupremraj M 2020-12-08 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33293549 Cerebral small vessel disease genomics and its implications across the lifespan. White matter hyperintensity volume (adjusted for hypertension) 2,469 African American individuals NA Affymetrix, Illumina [9900000] (imputed) 1 white matter hyperintensity measurement http://www.ebi.ac.uk/efo/EFO_0005665 GCST011951 Genome-wide genotyping array 2469 2021-06-22 33293549 Sargurupremraj M 2020-12-08 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33293549 Cerebral small vessel disease genomics and its implications across the lifespan. White matter hyperintensity volume (adjusted for hypertension) 46,055 European ancestry individuals NA Affymetrix, Illumina [9900000] (imputed) 43 white matter hyperintensity measurement http://www.ebi.ac.uk/efo/EFO_0005665 GCST011950 Genome-wide genotyping array 46055 2021-06-22 33293549 Sargurupremraj M 2020-12-08 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33293549 Cerebral small vessel disease genomics and its implications across the lifespan. White matter hyperintensity volume (adjusted for hypertension) 46,055 European ancestry individuals, 2,469 African American individuals NA Affymetrix, Illumina [9900000] (imputed) 46 white matter hyperintensity measurement http://www.ebi.ac.uk/efo/EFO_0005665 GCST011949 Genome-wide genotyping array 48524 2021-06-22 33293549 Sargurupremraj M 2020-12-08 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33293549 Cerebral small vessel disease genomics and its implications across the lifespan. White matter hyperintensity volume 2,516 African American individuals NA Affymetrix, Illumina [9900000] (imputed) 1 white matter hyperintensity measurement http://www.ebi.ac.uk/efo/EFO_0005665 GCST011948 Genome-wide genotyping array 2516 2021-06-22 33293549 Sargurupremraj M 2020-12-08 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33293549 Cerebral small vessel disease genomics and its implications across the lifespan. White matter hyperintensity volume 48,454 European ancestry individuals NA Affymetrix, Illumina [9900000] (imputed) 60 white matter hyperintensity measurement http://www.ebi.ac.uk/efo/EFO_0005665 GCST011947 Genome-wide genotyping array 48454 2021-06-22 33293549 Sargurupremraj M 2020-12-08 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33293549 Cerebral small vessel disease genomics and its implications across the lifespan. White matter hyperintensity volume 2,516 African American individuals, 48,454 European ancestry individuals NA Affymetrix, Illumina [9900000] (imputed) 47 white matter hyperintensity measurement http://www.ebi.ac.uk/efo/EFO_0005665 GCST011946 Genome-wide genotyping array 50970 2021-06-22 33293549 Sargurupremraj M 2020-12-08 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33293549 Cerebral small vessel disease genomics and its implications across the lifespan. White matter hyperintensity volume x hypertension interaction (2df) 2,469 African American individuals NA Affymetrix, Illumina [9900000] (imputed) 5 hypertension, white matter hyperintensity measurement http://www.ebi.ac.uk/efo/EFO_0000537, http://www.ebi.ac.uk/efo/EFO_0005665 GCST011954 Genome-wide genotyping array 2469 2021-03-23 32752121 Nedoszytko B 2020-07-31 Int J Mol Sci www.ncbi.nlm.nih.gov/pubmed/32752121 Results from a Genome-Wide Association Study (GWAS) in Mastocytosis Reveal New Gene Polymorphisms Associated with WHO Subgroups. Systemic mastocytosis 93 European ancestry cases, 5,606 European ancestry controls NA Illumina [281811] 17 systemic mastocytosis http://purl.obolibrary.org/obo/MONDO_0016586 GCST011382 Genome-wide genotyping array 5699 2021-03-23 32752121 Nedoszytko B 2020-07-31 Int J Mol Sci www.ncbi.nlm.nih.gov/pubmed/32752121 Results from a Genome-Wide Association Study (GWAS) in Mastocytosis Reveal New Gene Polymorphisms Associated with WHO Subgroups. Cutaneous mastocytosis 141 European ancestry cases, 5,606 European ancestry controls NA Illumina [281811] 10 cutaneous mastocytosis http://www.ebi.ac.uk/efo/EFO_1000886 GCST011381 Genome-wide genotyping array 5747 2021-03-23 32752121 Nedoszytko B 2020-07-31 Int J Mol Sci www.ncbi.nlm.nih.gov/pubmed/32752121 Results from a Genome-Wide Association Study (GWAS) in Mastocytosis Reveal New Gene Polymorphisms Associated with WHO Subgroups. Cutaneous mastocytosis (adult) 65 European ancestry cases, 5,606 European ancestry controls NA Illumina [281811] 4 cutaneous mastocytosis http://www.ebi.ac.uk/efo/EFO_1000886 GCST011380 Genome-wide genotyping array 5671 2021-03-23 32752121 Nedoszytko B 2020-07-31 Int J Mol Sci www.ncbi.nlm.nih.gov/pubmed/32752121 Results from a Genome-Wide Association Study (GWAS) in Mastocytosis Reveal New Gene Polymorphisms Associated with WHO Subgroups. Mastocytosis 234 European ancestry cases, 5,606 European ancestry controls NA Illumina [281811] 20 Mastocytosis http://www.ebi.ac.uk/efo/EFO_0009001 GCST011383 Genome-wide genotyping array 5840 2021-03-23 32752121 Nedoszytko B 2020-07-31 Int J Mol Sci www.ncbi.nlm.nih.gov/pubmed/32752121 Results from a Genome-Wide Association Study (GWAS) in Mastocytosis Reveal New Gene Polymorphisms Associated with WHO Subgroups. Cutaneous mastocytosis (childhood) 78 European ancestry cases, 5,606 European ancestry controls NA Illumina [281811] 11 cutaneous mastocytosis http://www.ebi.ac.uk/efo/EFO_1000886 GCST011379 Genome-wide genotyping array 5684 2020-09-10 32473944 Russell AE 2020-05-28 Brain Behav Immun www.ncbi.nlm.nih.gov/pubmed/32473944 Investigating evidence for a causal association between inflammation and self-harm: A multivariable Mendelian Randomisation study. Suicide attempts 3,470 European ancestry cases, 150,090 European ancestry controls NA Affymetrix [at least 143006] (imputed) 15 attempted suicide http://www.ebi.ac.uk/efo/EFO_0004321 GCST010505 Genome-wide genotyping array 153560 2020-09-10 32473944 Russell AE 2020-05-28 Brain Behav Immun www.ncbi.nlm.nih.gov/pubmed/32473944 Investigating evidence for a causal association between inflammation and self-harm: A multivariable Mendelian Randomisation study. Interleukin-6 levels 8,296 European ancestry individuals NA Illumina [NR] (imputed) 2 interleukin-6 measurement http://www.ebi.ac.uk/efo/EFO_0004810 GCST010504 Genome-wide genotyping array 8296 2020-09-10 32473944 Russell AE 2020-05-28 Brain Behav Immun www.ncbi.nlm.nih.gov/pubmed/32473944 Investigating evidence for a causal association between inflammation and self-harm: A multivariable Mendelian Randomisation study. Deliberate self-harm 6,711 European ancestry cases, 146,849 European ancestry controls NA Affymetrix [at least 143006] (imputed) 193 Self-injurious behavior http://purl.obolibrary.org/obo/HP_0100716 GCST010506 Genome-wide genotyping array 153560 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. 2-hydroxyisobutyrate levels 996 European ancestry individuals NA Illumina [283704] 0 2-hydroxyisobutyrate measurement http://www.ebi.ac.uk/efo/EFO_0010979 GCST90013539 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. 3-aminoisobutyrate levels 996 European ancestry individuals NA Illumina [283704] 0 3-aminoisobutyrate measurement http://www.ebi.ac.uk/efo/EFO_0010980 GCST90013540 Genome-wide genotyping array 996 2021-03-05 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. 3-hydroxybutyrate + 3-aminoisobutyrate levels 996 European ancestry individuals NA Illumina [283704] 2 3-aminoisobutyrate measurement, 3-hydroxyisobutyrate measurement http://www.ebi.ac.uk/efo/EFO_0010980, http://www.ebi.ac.uk/efo/EFO_0010983 GCST90013541 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. 3-hydroxyisobutyrate levels 996 European ancestry individuals NA Illumina [283704] 0 3-hydroxyisobutyrate measurement http://www.ebi.ac.uk/efo/EFO_0010983 GCST90013542 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. 3-hydroxyisovalerate levels 996 European ancestry individuals NA Illumina [283704] 0 3-hydroxyisovalerate measurement http://www.ebi.ac.uk/efo/EFO_0010984 GCST90013543 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. 3-Indoxylsulfate levels 996 European ancestry individuals NA Illumina [283704] 0 3-Indoxylsulfate measurement http://www.ebi.ac.uk/efo/EFO_0010985 GCST90013544 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. 4-deoxyerythronic acid levels 996 European ancestry individuals NA Illumina [283704] 0 4-deoxyerythronic acid measurement http://www.ebi.ac.uk/efo/EFO_0010986 GCST90013545 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. 4-deoxythreonic acid levels 996 European ancestry individuals NA Illumina [283704] 0 4-deoxythreonic acid measurement http://www.ebi.ac.uk/efo/EFO_0010987 GCST90013546 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. 5-oxoproline levels 996 European ancestry individuals NA Illumina [283704] 0 5-oxoproline measurement http://www.ebi.ac.uk/efo/EFO_0010988 GCST90013547 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Acetate levels 996 European ancestry individuals NA Illumina [283704] 0 acetate measurement http://www.ebi.ac.uk/efo/EFO_0010112 GCST90013548 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Acetone levels 996 European ancestry individuals NA Illumina [283704] 0 acetone measurement http://www.ebi.ac.uk/efo/EFO_0010989 GCST90013549 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Alanine levels 996 European ancestry individuals NA Illumina [283704] 0 alanine measurement http://www.ebi.ac.uk/efo/EFO_0009765 GCST90013550 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Carnitine levels 996 European ancestry individuals NA Illumina [283704] 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90013551 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Citrate levels 996 European ancestry individuals NA Illumina [283704] 0 citrate measurement http://www.ebi.ac.uk/efo/EFO_0010114 GCST90013552 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Creatine levels 996 European ancestry individuals NA Illumina [283704] 0 creatine measurement http://www.ebi.ac.uk/efo/EFO_0010472 GCST90013553 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Creatinine levels 996 European ancestry individuals NA Illumina [283704] 0 creatinine measurement http://www.ebi.ac.uk/efo/EFO_0004518 GCST90013554 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Dimethylamine levels 996 European ancestry individuals NA Illumina [283704] 0 dimethylamine measurement http://www.ebi.ac.uk/efo/EFO_0010990 GCST90013555 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Formate levels 996 European ancestry individuals NA Illumina [283704] 0 formate measurement http://www.ebi.ac.uk/efo/EFO_0010991 GCST90013556 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Glucose levels 996 European ancestry individuals NA Illumina [283704] 0 glucose measurement http://www.ebi.ac.uk/efo/EFO_0004468 GCST90013557 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Glutamine levels 996 European ancestry individuals NA Illumina [283704] 0 glutamine measurement http://www.ebi.ac.uk/efo/EFO_0009768 GCST90013558 Genome-wide genotyping array 996 2021-03-05 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Glycine levels 996 European ancestry individuals NA Illumina [283704] 1 glycine measurement http://www.ebi.ac.uk/efo/EFO_0009767 GCST90013559 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Hippurate levels 996 European ancestry individuals NA Illumina [283704] 0 hippurate measurement http://www.ebi.ac.uk/efo/EFO_0010992 GCST90013560 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Isoleucine levels 996 European ancestry individuals NA Illumina [283704] 0 isoleucine measurement http://www.ebi.ac.uk/efo/EFO_0009793 GCST90013561 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Lactate levels 996 European ancestry individuals NA Illumina [283704] 0 lactate measurement http://www.ebi.ac.uk/efo/EFO_0007745 GCST90013562 Genome-wide genotyping array 996 2021-02-17 33283231 Calvo-Serra B 2020-12-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33283231 Urinary metabolite quantitative trait loci in children and their interaction with dietary factors. Leucine levels 996 European ancestry individuals NA Illumina [283704] 0 leucine measurement http://www.ebi.ac.uk/efo/EFO_0009770 GCST90013563 Genome-wide genotyping array 996 2021-05-27 33109212 Chang H 2020-10-28 BMC Med www.ncbi.nlm.nih.gov/pubmed/33109212 Genetic architecture of cardiometabolic risks in people living with HIV. Triglyceride levels in HIV infection 3,095 European ancestry individuals, 3,189 African American individuals NA Illumina [13620258] (imputed) 70 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST011742 Genome-wide genotyping array 6284 2021-05-27 33109212 Chang H 2020-10-28 BMC Med www.ncbi.nlm.nih.gov/pubmed/33109212 Genetic architecture of cardiometabolic risks in people living with HIV. LDL cholesterol levels in HIV infection 3,095 European ancestry individuals, 3,189 African American individuals NA Illumina [13620258] (imputed) 76 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST011741 Genome-wide genotyping array 6284 2021-05-27 33109212 Chang H 2020-10-28 BMC Med www.ncbi.nlm.nih.gov/pubmed/33109212 Genetic architecture of cardiometabolic risks in people living with HIV. HDL cholesterol levels in HIV infection 3,095 European ancestry individuals, 3,189 African American individuals NA Illumina [13620258] (imputed) 86 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST011743 Genome-wide genotyping array 6284 2020-04-20 30642433 Timmers PR 2019-01-15 Elife www.ncbi.nlm.nih.gov/pubmed/30642433 Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances. Parental lifespan at least 500,193 European ancestry offspring NA NR [up to 9000000] (imputed) 16 parental longevity http://www.ebi.ac.uk/efo/EFO_0007796 GCST009890 Genome-wide genotyping array 500193 2021-02-11 32652002 Dauber A 2020-07-11 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/32652002 A Genomewide Pharmacogenetic Study of Growth Hormone Responsiveness. First year height change in growth hormone-treated short stature 504 European ancestry individuals, 88 individuals 113 Brazilian individuals Illumina [~ 2000000] (imputed) 2 response to growth hormone, height growth measurement http://www.ebi.ac.uk/efo/EFO_0010969, http://www.ebi.ac.uk/efo/EFO_0005201 GCST011107 Genome-wide genotyping array 592 2021-08-13 33632709 Huyghe JR 2021-02-25 Gut www.ncbi.nlm.nih.gov/pubmed/33632709 Genetic architectures of proximal and distal colorectal cancer are partly distinct. Distal/Left-sided colorectal cancer 30,588 European ancestry cases, 64,159 European ancestry controls NA Affymetrix, Illumina [11947015] (imputed) 6 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST012202 Genome-wide genotyping array 94747 2021-08-13 33632709 Huyghe JR 2021-02-25 Gut www.ncbi.nlm.nih.gov/pubmed/33632709 Genetic architectures of proximal and distal colorectal cancer are partly distinct. Proximal colorectal cancer 15,706 European ancestry cases, 64,159 European ancestry controls NA Affymetrix, Illumina [11437803] (imputed) 4 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST012206 Genome-wide genotyping array 79865 2021-08-13 33632709 Huyghe JR 2021-02-25 Gut www.ncbi.nlm.nih.gov/pubmed/33632709 Genetic architectures of proximal and distal colorectal cancer are partly distinct. Distal colorectal cancer 14,376 European ancestry cases, 64,159 European ancestry controls NA Affymetrix, Illumina [11353757] (imputed) 7 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST012205 Genome-wide genotyping array 78535 2021-08-13 33632709 Huyghe JR 2021-02-25 Gut www.ncbi.nlm.nih.gov/pubmed/33632709 Genetic architectures of proximal and distal colorectal cancer are partly distinct. Rectal cancer 16,212 European ancestry cases, 64,159 European ancestry controls NA Affymetrix, Illumina [11358342] (imputed) 3 rectum cancer http://www.ebi.ac.uk/efo/EFO_1000657 GCST012204 Genome-wide genotyping array 80371 2021-08-13 33632709 Huyghe JR 2021-02-25 Gut www.ncbi.nlm.nih.gov/pubmed/33632709 Genetic architectures of proximal and distal colorectal cancer are partly distinct. Colon cancer 32,002 European ancestry cases, 64,159 European ancestry controls NA Affymetrix, Illumina [11928745] (imputed) 3 colon carcinoma http://www.ebi.ac.uk/efo/EFO_1001950 GCST012203 Genome-wide genotyping array 96161 2020-06-26 32558485 Ellinghaus D 2020-06-17 N Engl J Med www.ncbi.nlm.nih.gov/pubmed/32558485 Genomewide Association Study of Severe Covid-19 with Respiratory Failure. Severe COVID-19 infection with respiratory failure (analysis I) 1,610 European ancestry cases, 2,205 European ancestry controls NA Illumina [8582968] (imputed) 23 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST90000255 Genome-wide genotyping array 3815 2020-06-26 32558485 Ellinghaus D 2020-06-17 N Engl J Med www.ncbi.nlm.nih.gov/pubmed/32558485 Genomewide Association Study of Severe Covid-19 with Respiratory Failure. Severe COVID-19 infection with respiratory failure (analysis II) 1,610 European ancestry cases, 2,180 European ancestry controls NA Illumina [8582560] (imputed) 2 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST90000256 Genome-wide genotyping array 3790 2020-09-21 32766472 Park SL 2020-06-25 Hepatol Commun www.ncbi.nlm.nih.gov/pubmed/32766472 Genome-Wide Association Study of Liver Fat: The Multiethnic Cohort Adiposity Phenotype Study. Nonalcoholic fatty liver disease 37 African American cases, 177 Japanese American cases, 140 Latino cases, 85 Native Hawaiian cases, 67 European ancestry cases, 218 African American controls, 221 Japanese American controls, 182 Latino controls, 158 Native Hawaiian controls, 244 European ancestry controls NA Illumina [9789995] (imputed) 8 non-alcoholic fatty liver disease http://www.ebi.ac.uk/efo/EFO_0003095 GCST010597 Genome-wide genotyping array 1529 2020-09-21 32766472 Park SL 2020-06-25 Hepatol Commun www.ncbi.nlm.nih.gov/pubmed/32766472 Genome-Wide Association Study of Liver Fat: The Multiethnic Cohort Adiposity Phenotype Study. Percent liver fat 269 African American individuals, 424 Japanese American individuals, 345 Latino individuals, 270 Native Hawaiian individuals, 382 European ancestry individuals NA Illumina [9789995] (imputed) 5 liver fat measurement http://www.ebi.ac.uk/efo/EFO_0010821 GCST010598 Genome-wide genotyping array 1690 2021-07-27 33382417 Batai K 2020-12-31 J Nutr www.ncbi.nlm.nih.gov/pubmed/33382417 Genome-Wide Association Study of Response to Selenium Supplementation and Circulating Selenium Concentrations in Adults of European Descent. Plasma selenium concentration 1,211 European ancestry individuals NA Illumina [7663546] (imputed) 3 selenium measurement http://www.ebi.ac.uk/efo/EFO_0006331 GCST012070 Genome-wide genotyping array 1211 2021-07-27 33382417 Batai K 2020-12-31 J Nutr www.ncbi.nlm.nih.gov/pubmed/33382417 Genome-Wide Association Study of Response to Selenium Supplementation and Circulating Selenium Concentrations in Adults of European Descent. Response to selenium supplementation (change in plasma selenium concentration) 428 European ancestry individuals NA Illumina [7663546] (imputed) 14 selenium measurement, response to dietary selenium supplementation http://www.ebi.ac.uk/efo/EFO_0006331, http://www.ebi.ac.uk/efo/EFO_0600021 GCST012071 Genome-wide genotyping array 428 2020-08-26 25998175 Larson NB 2015-05-22 Ann Hum Genet www.ncbi.nlm.nih.gov/pubmed/25998175 Trans-ethnic meta-analysis identifies common and rare variants associated with hepatocyte growth factor levels in the Multi-Ethnic Study of Atherosclerosis (MESA). Hepatocyte growth factor levels 1,550 African American individuals, 762 Chinese ancestry individuals, 2,477 European ancestry individuals, 1,412 Hispanic individuals NA Illumina [377173] 7 hepatocyte growth factor measurement http://www.ebi.ac.uk/efo/EFO_0006903 GCST010461 Targeted genotyping array [Exome array, Cardio-Metabochip] 6201 2020-05-29 32231276 Cai N 2020-03-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32231276 Minimal phenotyping yields genome-wide association signals of low specificity for major depression. Major depressive disorder (lifetime) 16,301 British ancestry cases, 50,870 British ancestry controls NA NR [5276842] (imputed) 4 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST010009 Genome-wide genotyping array 67171 2020-05-29 32231276 Cai N 2020-03-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32231276 Minimal phenotyping yields genome-wide association signals of low specificity for major depression. Major depressive disorder (lifetime with recurrence) 10,302 British ancestry cases, 49,083 British ancestry controls NA NR [5276842] (imputed) 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST010010 Genome-wide genotyping array 59385 2020-05-29 32231276 Cai N 2020-03-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32231276 Minimal phenotyping yields genome-wide association signals of low specificity for major depression. Help-seeking from a GP 113,262 British ancestry cases, 219,360 British ancestry controls NA NR [5276842] (imputed) 28 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST010011 Genome-wide genotyping array 332622 2020-05-29 32231276 Cai N 2020-03-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32231276 Minimal phenotyping yields genome-wide association signals of low specificity for major depression. Help-seeking from a psychiatrist 36,286 British ancestry cases, 297,126 British ancestry controls NA NR [5276842] (imputed) 5 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST010012 Genome-wide genotyping array 333412 2020-05-29 32231276 Cai N 2020-03-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32231276 Minimal phenotyping yields genome-wide association signals of low specificity for major depression. Major depressive disorder symptoms (low mood or anhedonia) 21,177 British ancestry cases, 58,398 British ancestry controls NA NR [5276842] (imputed) 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST010013 Genome-wide genotyping array 79575 2020-05-29 32231276 Cai N 2020-03-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32231276 Minimal phenotyping yields genome-wide association signals of low specificity for major depression. Help-seeking from a GP (without major depressive disorder symptoms) 8,632 British ancestry cases, 49,493 British ancestry controls NA NR [5276842] (imputed) 3 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST010014 Genome-wide genotyping array 58125 2020-05-29 32231276 Cai N 2020-03-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32231276 Minimal phenotyping yields genome-wide association signals of low specificity for major depression. Depression or depression symptoms 19,805 British ancestry cases, 234,114 British ancestry controls NA NR [5276842] (imputed) 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST010015 Genome-wide genotyping array 253919 2020-05-29 32231276 Cai N 2020-03-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32231276 Minimal phenotyping yields genome-wide association signals of low specificity for major depression. Depression 9,176 British ancestry cases, 203,235 British ancestry controls NA NR [5276842] (imputed) 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST010016 Genome-wide genotyping array 212411 2020-05-29 32231276 Cai N 2020-03-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32231276 Minimal phenotyping yields genome-wide association signals of low specificity for major depression. Neuroticism 274,107 British ancestry individuals NA NR [8968716] (imputed) 64 neurotic disorder http://www.ebi.ac.uk/efo/EFO_0004257 GCST010017 Genome-wide genotyping array 274107 2020-05-29 32231276 Cai N 2020-03-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32231276 Minimal phenotyping yields genome-wide association signals of low specificity for major depression. Smoking status (ever vs never smokers) 336,066 British ancestry individuals NA NR [8968716] (imputed) 36 smoking status measurement http://www.ebi.ac.uk/efo/EFO_0006527 GCST010018 Genome-wide genotyping array 336066 2021-03-24 32719433 Liu Y 2020-07-27 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/32719433 Four pleiotropic loci associated with fat mass and lean mass. Leg fat mass (lean adjusted) 9,684 European ancestry individuals, 1,541 Han Chinese ancestry individuals, 847 African American individuals, 445 Hispanic individuals 370,097 European ancestry individuals Affymetrix, Illumina [6879267] (imputed) 3 lean mass-adjusted fat body mass http://www.ebi.ac.uk/efo/EFO_0009890 GCST011393 Genome-wide genotyping array 12517 2021-03-24 32719433 Liu Y 2020-07-27 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/32719433 Four pleiotropic loci associated with fat mass and lean mass. Leg lean mass (fat adjusted) 9,684 European ancestry individuals, 1,541 Han Chinese ancestry individuals, 847 African American individuals, 445 Hispanic individuals 370,097 European ancestry individuals Affymetrix, Illumina [6879267] (imputed) 2 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST011392 Genome-wide genotyping array 12517 2021-03-24 32719433 Liu Y 2020-07-27 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/32719433 Four pleiotropic loci associated with fat mass and lean mass. Leg fat mass and leg lean mass (pleiotropy) 9,684 European ancestry individuals, 1,541 Han Chinese ancestry individuals, 847 African American individuals, 445 Hispanic individuals 370,097 European ancestry individuals Affymetrix, Illumina [6879267] (imputed) 4 fat body mass, lean body mass http://www.ebi.ac.uk/efo/EFO_0005409, http://www.ebi.ac.uk/efo/EFO_0004995 GCST011394 Genome-wide genotyping array 12517 2019-04-09 27548383 Ortiz-Fernandez L 2016-08-22 PLoS One www.ncbi.nlm.nih.gov/pubmed/27548383 Genetic Analysis with the Immunochip Platform in Behçet Disease. Identification of Residues Associated in the HLA Class I Region and New Susceptibility Loci. Behcet's disease 278 Spanish ancestry cases, 1,517 Spanish ancestry controls up to 130 Spanish ancestry cases, up to 605 Spanish ancestry controls Illumina [133018] 3 Behcet's syndrome http://www.ebi.ac.uk/efo/EFO_0003780 GCST007551 Targeted genotyping array [ImmunoChip] 1795 2021-03-24 33597508 Coignard J 2021-02-17 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33597508 A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers. BRCA1 mutation in breast cancer 7,257 European ancestry cases, 60,212 European ancestry controls NA Illumina [9068301] (imputed) 13 NA NA GCST011402 Genome-wide genotyping array 67469 2021-03-24 33597508 Coignard J 2021-02-17 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33597508 A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers. BRCA2 mutation in breast cancer 5,097 European ancestry cases, 57,725 European ancestry controls NA Illumina [9043830] (imputed) 10 NA NA GCST011401 Genome-wide genotyping array 62822 2021-03-24 33597508 Coignard J 2021-02-17 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33597508 A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers. BRCA1 mutation in healthy women 5,750 European ancestry cases, 45,881 European ancestry controls NA Illumina [NR] (imputed) 0 NA NA GCST011400 Genome-wide genotyping array 51631 2021-03-24 33597508 Coignard J 2021-02-17 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33597508 A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers. BRCA2 mutation in healthy women 4,456 European ancestry cases, 43,549 European ancestry controls NA Illumina [NR] (imputed) 0 NA NA GCST011399 Genome-wide genotyping array 48005 2021-08-10 33607655 Imamura M 2021-02-19 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33607655 Genome-Wide Association Studies Identify Two Novel Loci Conferring Susceptibility to Diabetic Retinopathy in Japanese Patients with Type 2 Diabetes. Diabetic retinopathy in type 2 diabetes 5,532 Japanese ancestry cases, 5,565 Japanese ancestry controls 3,010 Japanese ancestry cases, 1,562 Japanese ancestry controls Illumina [5790508] (imputed) 6 diabetic retinopathy http://www.ebi.ac.uk/efo/EFO_0003770 GCST012174 Genome-wide genotyping array 11097 2021-08-05 33607172 Nygaard M 2021-02-16 Mech Ageing Dev www.ncbi.nlm.nih.gov/pubmed/33607172 Genome-wide association analysis of cognitive function in Danish long-lived individuals. Cognitive function in longevity 490 Danish ancestry individuals NA Illumina [4827900] (imputed) 14 cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0008354 GCST012170 Genome-wide genotyping array 490 2021-06-15 33603002 Gouveia MH 2021-02-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33603002 Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits. Diastolic blood pressure (long-term average) 5,304 African American individuals 6,500 African American individuals Affymetrix, Illumina [NR] (imputed) 9 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST011905 Genome-wide genotyping array 5304 2021-06-15 33603002 Gouveia MH 2021-02-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33603002 Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits. Systolic blood pressure (baseline) 5,304 African American individuals 6,500 African American individuals Affymetrix, Illumina [NR] (imputed) 26 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST011902 Genome-wide genotyping array 5304 2021-06-15 33603002 Gouveia MH 2021-02-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33603002 Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits. Diastolic blood pressure change trajectory 5,304 African American individuals 6,500 African American individuals Affymetrix, Illumina [NR] (imputed) 6 diastolic blood pressure change measurement http://www.ebi.ac.uk/efo/EFO_0006945 GCST011904 Genome-wide genotyping array 5304 2021-06-15 33603002 Gouveia MH 2021-02-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33603002 Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits. Systolic blood pressure (long-term average) 5,304 African American individuals 6,500 African American individuals Affymetrix, Illumina [NR] (imputed) 19 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST011903 Genome-wide genotyping array 5304 2021-06-15 33603002 Gouveia MH 2021-02-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33603002 Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits. Systolic blood pressure change trajectory 5,304 African American individuals 6,500 African American individuals Affymetrix, Illumina [NR] (imputed) 9 systolic blood pressure change measurement http://www.ebi.ac.uk/efo/EFO_0006944 GCST011901 Genome-wide genotyping array 5304 2021-06-15 33603002 Gouveia MH 2021-02-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33603002 Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits. Diastolic blood pressure (long-term average) 13,137 European ancestry individuals 2,451 European ancestry individuals Affymetrix, Illumina [NR] (imputed) 13 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST011899 Genome-wide genotyping array 13137 2021-06-15 33603002 Gouveia MH 2021-02-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33603002 Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits. Diastolic blood pressure (baseline) 13,137 European ancestry individuals 2,451 European ancestry individuals Affymetrix, Illumina [NR] (imputed) 12 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST011900 Genome-wide genotyping array 13137 2021-06-15 33603002 Gouveia MH 2021-02-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33603002 Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits. Diastolic blood pressure change trajectory 13,137 European ancestry individuals 2,451 European ancestry individuals Affymetrix, Illumina [NR] (imputed) 4 diastolic blood pressure change measurement http://www.ebi.ac.uk/efo/EFO_0006945 GCST011898 Genome-wide genotyping array 13137 2021-06-15 33603002 Gouveia MH 2021-02-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33603002 Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits. Systolic blood pressure (baseline) 13,137 European ancestry individuals 2,451 European ancestry individuals Affymetrix, Illumina [NR] (imputed) 2 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST011897 Genome-wide genotyping array 13137 2021-06-15 33603002 Gouveia MH 2021-02-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33603002 Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits. Systolic blood pressure change trajectory 13,137 European ancestry individuals 2,451 European ancestry individuals Affymetrix, Illumina [NR] (imputed) 4 systolic blood pressure change measurement http://www.ebi.ac.uk/efo/EFO_0006944 GCST011896 Genome-wide genotyping array 13137 2021-06-15 33603002 Gouveia MH 2021-02-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33603002 Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits. Diastolic blood pressure (long-term average) 5,304 African American individuals, 13,137 European ancestry individuals, 1,317 Hispanic individuals, 1,439 admixed individuals, 703 Chinese ancestry individuals 6,500 African American individuals, 2,451 European ancestry individuals, 2,869 Hispanic individuals Affymetrix, Illumina [NR] (imputed) 20 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST011895 Genome-wide genotyping array 21900 2021-06-15 33603002 Gouveia MH 2021-02-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33603002 Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits. Diastolic blood pressure (baseline) 5,304 African American individuals, 13,137 European ancestry individuals, 1,317 Hispanic individuals, 1,439 admixed individuals, 703 Chinese ancestry individuals 6,500 African American individuals, 2,451 European ancestry individuals, 2,869 Hispanic individuals Affymetrix, Illumina [NR] (imputed) 15 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST011894 Genome-wide genotyping array 21900 2021-06-15 33603002 Gouveia MH 2021-02-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33603002 Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits. Diastolic blood pressure change trajectory 5,304 African American individuals, 13,137 European ancestry individuals, 1,317 Hispanic individuals, 1,439 admixed individuals, 703 Chinese ancestry individuals 6,500 African American individuals, 2,451 European ancestry individuals, 2,869 Hispanic individuals Affymetrix, Illumina [NR] (imputed) 19 diastolic blood pressure change measurement http://www.ebi.ac.uk/efo/EFO_0006945 GCST011893 Genome-wide genotyping array 21900 2021-06-15 33603002 Gouveia MH 2021-02-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33603002 Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits. Systolic blood pressure (long-term average) 5,304 African American individuals, 13,137 European ancestry individuals, 1,317 Hispanic individuals, 1,439 admixed individuals, 703 Chinese ancestry individuals 6,500 African American individuals, 2,451 European ancestry individuals, 2,869 Hispanic individuals Affymetrix, Illumina [NR] (imputed) 28 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST011892 Genome-wide genotyping array 21900 2021-06-15 33603002 Gouveia MH 2021-02-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33603002 Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits. Systolic blood pressure (baseline) 5,304 African American individuals, 13,137 European ancestry individuals, 1,317 Hispanic individuals, 1,439 admixed individuals, 703 Chinese ancestry individuals 6,500 African American individuals, 2,451 European ancestry individuals, 2,869 Hispanic individuals Affymetrix, Illumina [NR] (imputed) 22 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST011891 Genome-wide genotyping array 21900 2021-06-15 33603002 Gouveia MH 2021-02-18 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33603002 Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits. Systolic blood pressure change trajectory 5,304 African American individuals, 13,137 European ancestry individuals, 1,317 Hispanic individuals, 1,439 admixed individuals, 703 Chinese ancestry individuals 6,500 African American individuals, 2,451 European ancestry individuals, 2,869 Hispanic individuals Affymetrix, Illumina [NR] (imputed) 8 systolic blood pressure change measurement http://www.ebi.ac.uk/efo/EFO_0006944 GCST011890 Genome-wide genotyping array 21900 2021-07-28 33500527 Park JM 2021-01-26 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33500527 Understanding the genetic architecture of the metabolically unhealthy normal weight and metabolically healthy obese phenotypes in a Korean population. Metabolically unhealthy in obesity 9,083 Korean ancestry cases, 7,008 Korean ancestry controls NA Affymetrix [7975321] 3 metabolic syndrome http://www.ebi.ac.uk/efo/EFO_0000195 GCST012148 Genome-wide genotyping array 16091 2021-07-28 33500527 Park JM 2021-01-26 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33500527 Understanding the genetic architecture of the metabolically unhealthy normal weight and metabolically healthy obese phenotypes in a Korean population. Metabolically unhealthy in normal weight 10,358 Korean ancestry cases, 23,466 Korean ancestry controls NA Affymetrix [7975321] 9 metabolic syndrome http://www.ebi.ac.uk/efo/EFO_0000195 GCST012149 Genome-wide genotyping array 33824 2019-03-02 30383316 Malik R 2018-11-01 Ann Neurol www.ncbi.nlm.nih.gov/pubmed/30383316 Genome-Wide Meta-analysis identifies three novel loci associated with stroke. Ischemic stroke 37,845 European ancestry cases, 26,124 cases, 775,530 European ancestry controls, 48,339 controls NA NR [NR] 0 Ischemic stroke http://purl.obolibrary.org/obo/HP_0002140 GCST007249 Genome-wide genotyping array 887838 2019-03-02 30383316 Malik R 2018-11-01 Ann Neurol www.ncbi.nlm.nih.gov/pubmed/30383316 Genome-Wide Meta-analysis identifies three novel loci associated with stroke. Stroke 45,570 European ancestry cases, 26,577 cases, 775,530 European ancestry controls, 48,339 controls NA NR [NR] 3 stroke http://www.ebi.ac.uk/efo/EFO_0000712 GCST007248 Genome-wide genotyping array 896016 2018-10-17 30145303 Kimbrel NA 2018-07-17 Psychiatry Res www.ncbi.nlm.nih.gov/pubmed/30145303 A genome-wide association study of suicide attempts and suicidal ideation in U.S. military veterans. Suicidal ideation 79 European ancestry cases, 59 cases, 654 European ancestry controls, 779 controls NA Illumina [2711511] (imputed) 25 suicidal ideation http://www.ebi.ac.uk/efo/EFO_0004320 GCST006429 Genome-wide genotyping array 1571 2018-10-17 30145303 Kimbrel NA 2018-07-17 Psychiatry Res www.ncbi.nlm.nih.gov/pubmed/30145303 A genome-wide association study of suicide attempts and suicidal ideation in U.S. military veterans. Suicide attempts 52 European ancestry cases, 70 cases, 680 European ancestry controls, 767 controls NA Illumina [2711511] (imputed) 22 attempted suicide http://www.ebi.ac.uk/efo/EFO_0004321 GCST006428 Genome-wide genotyping array 1569 2019-05-20 30837455 Dudding T 2019-03-05 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30837455 Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci. Mouth ulcers 47,079 British or unknown ancestry cases, 414,027 British or unknown ancestry controls 98,298 cases, 247,446 controls Affymetrix, Illumina [9851866] (imputed) 94 Oral ulcer http://purl.obolibrary.org/obo/HP_0000155 GCST007839 Genome-wide genotyping array 461106 2021-05-14 32846279 Zheng Q 2020-06-29 Sleep Med www.ncbi.nlm.nih.gov/pubmed/32846279 Identification of genetic loci jointly influencing coronary artery disease risk and sleep traits of insomnia, sleep duration, and chronotype. Coronary artery disease and insomnia (pleiotropy) 60,801 European, South Asian, East Asian, Hispanic and African American ancestry coronary artery disease cases, 109,402 European ancestry insomnia cases, 400,635 European, South Asian, East Asian, Hispanic and African American ancestry controls NA Affymetrix [up to 10848137] (imputed) 0 insomnia, coronary artery disease http://www.ebi.ac.uk/efo/EFO_0004698, http://www.ebi.ac.uk/efo/EFO_0001645 GCST011660 Genome-wide genotyping array 570838 2021-05-14 32846279 Zheng Q 2020-06-29 Sleep Med www.ncbi.nlm.nih.gov/pubmed/32846279 Identification of genetic loci jointly influencing coronary artery disease risk and sleep traits of insomnia, sleep duration, and chronotype. Coronary artery disease and sleep duration (pleiotropy) 60,801 European, South Asian, East Asian, Hispanic and African American ancestry coronary artery disease cases, 384,317 European ancestry individuals with sleep duration measurements, 123,504 European, South Asian, East Asian, Hispanic and African American ancestry controls NA Affymetrix [up to 10848137] (imputed) 0 sleep duration, coronary artery disease http://www.ebi.ac.uk/efo/EFO_0005271, http://www.ebi.ac.uk/efo/EFO_0001645 GCST011659 Genome-wide genotyping array 568622 2021-05-14 32846279 Zheng Q 2020-06-29 Sleep Med www.ncbi.nlm.nih.gov/pubmed/32846279 Identification of genetic loci jointly influencing coronary artery disease risk and sleep traits of insomnia, sleep duration, and chronotype. Coronary artery disease and chronotype (pleiotropy) 60,801 European, South Asian, East Asian, Hispanic and African American ancestry coronary artery disease cases, 345,552 European ancestry individuals with chronotype measurement, 123,504 European, South Asian, East Asian, Hispanic and African American ancestry controls NA Affymetrix [up to 10848137] (imputed) 0 chronotype measurement, coronary artery disease http://www.ebi.ac.uk/efo/EFO_0008328, http://www.ebi.ac.uk/efo/EFO_0001645 GCST011658 Genome-wide genotyping array 529857 2021-04-06 32839289 Milne S 2020-08-24 Thorax www.ncbi.nlm.nih.gov/pubmed/32839289 Protective effect of club cell secretory protein (CC-16) on COPD risk and progression: a Mendelian randomisation study. Serum CC16 levels 5,552 individuals NA Illumina [7312348] (imputed) 6 CC16 measurement http://www.ebi.ac.uk/efo/EFO_0005080 GCST011456 Genome-wide genotyping array 5552 2019-02-14 30258056 Vojinovic D 2018-09-26 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30258056 Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume. Lateral ventricular volume in normal aging 22,045 European ancestry individuals, 1,488 African American individuals NA Affymetrix, Illumina [NR] (imputed) 7 lateral ventricle volume measurement http://www.ebi.ac.uk/efo/EFO_0008487 GCST007147 Genome-wide genotyping array 23533 2019-02-14 30261039 Suri P 2018-09-27 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30261039 Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain. Chronic back pain 29,531 European ancestry cases, 128,494 European ancestry controls 50,915 British ancestry cases, 232,837 British ancestry controls Affymetrix, Illumina [up to 9775703] (imputed) 4 Back pain http://purl.obolibrary.org/obo/HP_0003418 GCST007152 Genome-wide genotyping array 158025 2021-04-19 33585033 Hayashi S 2021-01-29 Biomed Rep www.ncbi.nlm.nih.gov/pubmed/33585033 A genome-wide association study identifying the SNPs predictive of rapid joint destruction in patients with rheumatoid arthritis. joint destruction in rheumatoid arthritis (rapid vs slow) 32 Japanese ancestry rapid joint destruction individuals, 208 Japanese ancestry slow joint destruction individuals NA Illumina [up to 317503] 9 joint damage measurement http://www.ebi.ac.uk/efo/EFO_0005413 GCST011517 Genome-wide genotyping array 240 2021-04-19 33585033 Hayashi S 2021-01-29 Biomed Rep www.ncbi.nlm.nih.gov/pubmed/33585033 A genome-wide association study identifying the SNPs predictive of rapid joint destruction in patients with rheumatoid arthritis. joint destruction in rheumatoid arthritis (rapid vs slow) 30 Japanese ancestry rapid joint destruction individuals, 198 Japanese ancestry slow joint destruction individuals NA Illumina [up to 317503] 10 joint damage measurement http://www.ebi.ac.uk/efo/EFO_0005413 GCST011516 Genome-wide genotyping array 228 2021-03-22 33594131 Donati G 2021-02-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33594131 Evidence for specificity of polygenic contributions to attainment in English, maths and science during adolescence. Academic attainment (English) 5,983 European ancestry adolescents NA Illumina [6319684] (imputed) 16 educational attainment http://www.ebi.ac.uk/efo/EFO_0011015 GCST011358 Genome-wide genotyping array 5983 2021-03-22 33594131 Donati G 2021-02-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33594131 Evidence for specificity of polygenic contributions to attainment in English, maths and science during adolescence. Academic attainment (maths) 6,017 European ancestry adolescents NA Illumina [6319684] (imputed) 38 educational attainment http://www.ebi.ac.uk/efo/EFO_0011015 GCST011357 Genome-wide genotyping array 6017 2021-03-22 33594131 Donati G 2021-02-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33594131 Evidence for specificity of polygenic contributions to attainment in English, maths and science during adolescence. Academic attainment (science) 6,089 European ancestry adolescents NA Illumina [6319684] (imputed) 27 educational attainment http://www.ebi.ac.uk/efo/EFO_0011015 GCST011356 Genome-wide genotyping array 6089 2021-08-13 33597122 Verbitsky M 2021-02-17 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/33597122 Copy Number Variant Analysis and Genome-wide Association Study Identify Loci with Large Effect for Vesicoureteral Reflux. Vesicoureteral reflux 1,395 European ancestry cases, 5,366 European ancestry controls NA Affymetrix, Illumina [6131010] (imputed) 32 vesicoureteral reflux http://www.ebi.ac.uk/efo/EFO_0007536 GCST012183 Genome-wide genotyping array 6761 2021-03-22 33592630 Herrera-Rivero M 2021-02-16 Thromb Haemost www.ncbi.nlm.nih.gov/pubmed/33592630 Single- and Multimarker Genome-Wide Scans Evidence Novel Genetic Risk Modifiers for Venous Thromboembolism. Venous thromboembolism 964 European ancestry cases, 899 European ancestry controls NA Illumina [484621] 20 venous thromboembolism http://www.ebi.ac.uk/efo/EFO_0004286 GCST011359 Genome-wide genotyping array 1863 2021-08-04 33589587 Sakaue S 2021-02-15 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33589587 Genetic determinants of risk in autoimmune pulmonary alveolar proteinosis. Autoimmune pulmonary alveolar proteinosis 198 Japanese ancestry cases, 395 Japanese ancestry controls NA Illumina [12153232] (imputed) 2 pulmonary alveolar proteinosis http://purl.obolibrary.org/obo/MONDO_0001437 GCST012169 Genome-wide genotyping array 593 2021-03-01 33574239 Eriksson D 2021-02-11 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33574239 GWAS for autoimmune Addison's disease identifies multiple risk loci and highlights AIRE in disease susceptibility. Addison's disease 1,223 European ancestry cases, 4,097 European ancestry controls NA Illumina [7068382] (imputed) 10 Addison disease http://purl.obolibrary.org/obo/MONDO_0009410 GCST90011871 Genome-wide genotyping array 5320 2018-12-19 29665250 Shimanoe C 2018-04-17 Genes Brain Behav www.ncbi.nlm.nih.gov/pubmed/29665250 A genome-wide association study of coping behaviors suggests FBXO45 is associated with emotional expression. Emotional support seeking 6,403 Japanese ancestry individuals 7,685 Japanese ancestry individuals Illumina [7094228] (imputed) 0 coping behaviour measurement http://www.ebi.ac.uk/efo/EFO_0009480 GCST006819 Genome-wide genotyping array 6403 2018-12-19 29665250 Shimanoe C 2018-04-17 Genes Brain Behav www.ncbi.nlm.nih.gov/pubmed/29665250 A genome-wide association study of coping behaviors suggests FBXO45 is associated with emotional expression. Positive reappraisal 6,403 Japanese ancestry individuals 7,685 Japanese ancestry individuals Illumina [7094228] (imputed) 0 coping behaviour measurement http://www.ebi.ac.uk/efo/EFO_0009480 GCST006820 Genome-wide genotyping array 6403 2018-12-19 29665250 Shimanoe C 2018-04-17 Genes Brain Behav www.ncbi.nlm.nih.gov/pubmed/29665250 A genome-wide association study of coping behaviors suggests FBXO45 is associated with emotional expression. Problem solving 6,403 Japanese ancestry individuals 7,685 Japanese ancestry individuals Illumina [7094228] (imputed) 0 coping behaviour measurement http://www.ebi.ac.uk/efo/EFO_0009480 GCST006821 Genome-wide genotyping array 6403 2018-12-19 29665250 Shimanoe C 2018-04-17 Genes Brain Behav www.ncbi.nlm.nih.gov/pubmed/29665250 A genome-wide association study of coping behaviors suggests FBXO45 is associated with emotional expression. Disengagement 6,403 Japanese ancestry individuals 7,685 Japanese ancestry individuals Illumina [7094228] (imputed) 0 coping behaviour measurement http://www.ebi.ac.uk/efo/EFO_0009480 GCST006822 Genome-wide genotyping array 6403 2018-12-19 29665250 Shimanoe C 2018-04-17 Genes Brain Behav www.ncbi.nlm.nih.gov/pubmed/29665250 A genome-wide association study of coping behaviors suggests FBXO45 is associated with emotional expression. Emotional coping (emotional expression/emotional support seeking) 6,403 Japanese ancestry individuals 7,685 Japanese ancestry individuals Illumina [7094228] (imputed) 0 coping behaviour measurement http://www.ebi.ac.uk/efo/EFO_0009480 GCST006823 Genome-wide genotyping array 6403 2018-12-19 29665250 Shimanoe C 2018-04-17 Genes Brain Behav www.ncbi.nlm.nih.gov/pubmed/29665250 A genome-wide association study of coping behaviors suggests FBXO45 is associated with emotional expression. Approach coping (positive reappraisal/problem solving) 6,403 Japanese ancestry individuals 7,685 Japanese ancestry individuals Illumina [7094228] (imputed) 0 coping behaviour measurement http://www.ebi.ac.uk/efo/EFO_0009480 GCST006824 Genome-wide genotyping array 6403 2018-12-19 29665250 Shimanoe C 2018-04-17 Genes Brain Behav www.ncbi.nlm.nih.gov/pubmed/29665250 A genome-wide association study of coping behaviors suggests FBXO45 is associated with emotional expression. Perceived stress 6,403 Japanese ancestry individuals 7,685 Japanese ancestry individuals Illumina [7094228] (imputed) 0 psychosocial stress measurement http://www.ebi.ac.uk/efo/EFO_0006783 GCST006825 Genome-wide genotyping array 6403 2018-12-19 29665250 Shimanoe C 2018-04-17 Genes Brain Behav www.ncbi.nlm.nih.gov/pubmed/29665250 A genome-wide association study of coping behaviors suggests FBXO45 is associated with emotional expression. Emotional expression 6,403 Japanese ancestry individuals 7,685 Japanese ancestry individuals Illumina [7094228] (imputed) 0 coping behaviour measurement http://www.ebi.ac.uk/efo/EFO_0009480 GCST006826 Genome-wide genotyping array 6403 2021-03-01 33590662 Heilbronner U 2021-02-15 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/33590662 """The Heidelberg Five"" personality dimensions: Genome-wide associations, polygenic risk for neuroticism, and psychopathology 20 years after assessment." Emotional lability 3,268 European ancestry individuals NA Illumina [8348463] (imputed) 4 mood instability measurement http://www.ebi.ac.uk/efo/EFO_0008475 GCST90013452 Genome-wide genotyping array 3268 2021-03-01 33590662 Heilbronner U 2021-02-15 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/33590662 """The Heidelberg Five"" personality dimensions: Genome-wide associations, polygenic risk for neuroticism, and psychopathology 20 years after assessment." Lack of behavioral control 3,268 European ancestry individuals NA Illumina [8348463] (imputed) 7 behavioural disinhibition measurement http://www.ebi.ac.uk/efo/EFO_0006946 GCST90013453 Genome-wide genotyping array 3268 2021-03-01 33590662 Heilbronner U 2021-02-15 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/33590662 """The Heidelberg Five"" personality dimensions: Genome-wide associations, polygenic risk for neuroticism, and psychopathology 20 years after assessment." Type A behavior 3,268 European ancestry individuals NA Illumina [8348463] (imputed) 4 extraversion measurement http://www.ebi.ac.uk/efo/EFO_0007913 GCST90013454 Genome-wide genotyping array 3268 2021-03-01 33590662 Heilbronner U 2021-02-15 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/33590662 """The Heidelberg Five"" personality dimensions: Genome-wide associations, polygenic risk for neuroticism, and psychopathology 20 years after assessment." Locus of control over disease 3,268 European ancestry individuals NA Illumina [8348463] (imputed) 2 behavioural inhibitory control measurement http://www.ebi.ac.uk/efo/EFO_0008467 GCST90013455 Genome-wide genotyping array 3268 2021-03-01 33590662 Heilbronner U 2021-02-15 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/33590662 """The Heidelberg Five"" personality dimensions: Genome-wide associations, polygenic risk for neuroticism, and psychopathology 20 years after assessment." Psychoticism 3,268 European ancestry individuals NA Illumina [8348463] (imputed) 5 psychotic symptom measurement http://www.ebi.ac.uk/efo/EFO_0009182 GCST90013456 Genome-wide genotyping array 3268 2019-04-05 30657218 Park SY 2019-01-18 Clin Exp Allergy www.ncbi.nlm.nih.gov/pubmed/30657218 Longitudinal analysis to better characterize Asthma-COPD Overlap Syndrome (ACOS): Findings from an adult asthma cohort in Korea (COREA). Adult asthma 731 Korean ancestry cases, 5,915 Korean ancestry controls NA NR [267429] 2 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST007519 Genome-wide genotyping array 6646 2019-04-05 30657218 Park SY 2019-01-18 Clin Exp Allergy www.ncbi.nlm.nih.gov/pubmed/30657218 Longitudinal analysis to better characterize Asthma-COPD Overlap Syndrome (ACOS): Findings from an adult asthma cohort in Korea (COREA). Asthma-chronic obstructive pulmonary disease overlap syndrome in asthma 228 Korean ancestry asthma-COPD overlap syndrome cases, 731 Korean ancestry asthma cases NA NR [267429] 0 Chronic Obstructive Asthma http://www.ebi.ac.uk/efo/EFO_0009759 GCST007520 Genome-wide genotyping array 959 2019-04-05 30657218 Park SY 2019-01-18 Clin Exp Allergy www.ncbi.nlm.nih.gov/pubmed/30657218 Longitudinal analysis to better characterize Asthma-COPD Overlap Syndrome (ACOS): Findings from an adult asthma cohort in Korea (COREA). Asthma-chronic obstructive pulmonary disease overlap syndrome 228 Korean ancestry cases, 5,915 Korean ancestry controls NA Korean Chip 5 Chronic Obstructive Asthma http://www.ebi.ac.uk/efo/EFO_0009759 GCST007521 Genome-wide genotyping array 6143 2018-10-18 30120420 Sun R 2018-08-17 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30120420 Identification of novel loci associated with infant cognitive ability. Motor composite score 502 Bangladeshi ancestry infants, 462 Hispanic or Latin American infants NA Illumina [552487] 5 motor development measurement http://www.ebi.ac.uk/efo/EFO_0008237 GCST006440 Genome-wide genotyping array 964 2018-10-18 30120420 Sun R 2018-08-17 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30120420 Identification of novel loci associated with infant cognitive ability. Mental composite score 502 Bangladeshi ancestry infants, 462 Hispanic or Latin American infants NA Illumina [552487] 7 mental development measurement http://www.ebi.ac.uk/efo/EFO_0008230 GCST006441 Genome-wide genotyping array 964 2021-03-02 33593824 Wang YN 2021-02-16 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/33593824 Interaction between G ALNT12 and C1GALT1 Associates with Galactose-Deficient IgA1 and IgA Nephropathy. Serum galactose-deficient IgA1 levels in IgA nephropathy 849 Han Chinese ancestry individuals 313 Han Chinese ancestry individuals Illumina [5737162] (imputed) 2 serum galactose-deficient IgA1 measurement http://www.ebi.ac.uk/efo/EFO_0007947 GCST90011884 Genome-wide genotyping array 849 2020-09-14 32541925 Vujkovic M 2020-06-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32541925 Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis. Type 2 diabetes 148,726 European ancestry cases, 24,646 African American cases, 8,616 Hispanic cases, 46,511 Asian ancestry cases, 965,732 European ancestry controls, 31,446 African American controls, 11,829 Hispanic controls, 169,776 Asian ancestry controls NA Affymetrix, Illumina [at least 945603] (imputed) 558 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST010557 Genome-wide genotyping array 1407282 2020-09-14 32541925 Vujkovic M 2020-06-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32541925 Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis. Type 2 diabetes 24,646 African American cases, 31,446 African American controls NA Affymetrix, Illumina [945603] (imputed) 28 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST010556 Genome-wide genotyping array 56092 2020-09-14 32541925 Vujkovic M 2020-06-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32541925 Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis. Type 2 diabetes 148,726 European ancestry cases, 965,732 European ancestry controls NA Affymetrix, Illumina [1198787] (imputed) 658 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST010555 Genome-wide genotyping array 1114458 2020-09-14 32541925 Vujkovic M 2020-06-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32541925 Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis. Type 2 diabetes 8,616 Hispanic cases, 11,829 Hispanic controls NA Affymetrix, Illumina [1077427] (imputed) 2 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST010554 Genome-wide genotyping array 20445 2020-09-14 32541925 Vujkovic M 2020-06-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32541925 Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis. Type 2 diabetes 46,511 Asian ancestry cases, 169,776 Asian ancestry controls NA Affymetrix, Illumina [1077427] (imputed) 86 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST010553 Genome-wide genotyping array 216287 2020-09-14 32541925 Vujkovic M 2020-06-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32541925 Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis. Chronic kidney disease x type 2 diabetes interaction 67,403 European ancestry cases, 129,827 European ancestry controls NA Affymetrix [at least 723305] (imputed) 2 chronic kidney disease, type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0003884, http://www.ebi.ac.uk/efo/EFO_0001360 GCST010552 Genome-wide genotyping array 197230 2020-09-14 32541925 Vujkovic M 2020-06-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32541925 Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis. Peripheral arterial disease x type 2 diabetes interaction 5,882 European ancestry cases, 161,348 European ancestry controls NA Affymetrix [at least 723305] (imputed) 1 type II diabetes mellitus, peripheral arterial disease http://www.ebi.ac.uk/efo/EFO_0001360, http://www.ebi.ac.uk/efo/EFO_0004265 GCST010549 Genome-wide genotyping array 167230 2020-09-14 32541925 Vujkovic M 2020-06-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32541925 Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis. Coronary heart disease x type 2 diabetes interaction 56,285 European ancestry coronary heart disease cases, 140,945 European ancestry controls NA Affymetrix [at least 723305] (imputed) 3 type II diabetes mellitus, coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001360, http://www.ebi.ac.uk/efo/EFO_0001645 GCST010551 Genome-wide genotyping array 197230 2020-09-14 32541925 Vujkovic M 2020-06-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32541925 Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis. Acute ischemic stroke x type 2 diabetes interaction 11,796 European ancestry cases, 178,481 European ancestry controls NA Affymetrix [at least 723305] (imputed) 2 Ischemic stroke, type II diabetes mellitus http://purl.obolibrary.org/obo/HP_0002140, http://www.ebi.ac.uk/efo/EFO_0001360 GCST010550 Genome-wide genotyping array 190277 2020-09-14 32541925 Vujkovic M 2020-06-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32541925 Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis. Retinopathy x type 2 diabetes interaction 13,881 European ancestry cases, 123,538 European ancestry controls NA Affymetrix [at least 723305] (imputed) 4 retinopathy, type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0003839, http://www.ebi.ac.uk/efo/EFO_0001360 GCST010548 Genome-wide genotyping array 137419 2020-09-14 32541925 Vujkovic M 2020-06-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32541925 Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis. Neuropathy x type 2 diabetes interaction 40,475 European ancestry cases, 110,331 European ancestry controls NA Affymetrix [at least 723305] (imputed) 1 type II diabetes mellitus, neuropathy http://www.ebi.ac.uk/efo/EFO_0001360, http://www.ebi.ac.uk/efo/EFO_0004149 GCST010547 Genome-wide genotyping array 150806 2019-04-25 30837465 Wittemans LBL 2019-03-05 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30837465 Assessing the causal association of glycine with risk of cardio-metabolic diseases. Glycine levels 80,003 European ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 50 glycine measurement http://www.ebi.ac.uk/efo/EFO_0009767 GCST007638 Genome-wide genotyping array 80003 2020-10-29 32843070 Winkler TW 2020-08-26 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/32843070 Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease. Early age-related macular degeneration 14,034 European ancestry cases, 91,214 European ancestry controls NA Affymetrix, Illumina [11702853] (imputed) 8 age-related macular degeneration http://www.ebi.ac.uk/efo/EFO_0001365 GCST010723 Genome-wide genotyping array 105248 2019-07-29 28585551 Sigurdsson S 2017-06-06 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28585551 Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis. Diverticular disease 5,426 Icelandic ancestry cases, 245,951 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals) 5,970 Danish ancestry cases, 3,020 Danish ancestry controls Illumina [32463443] (imputed) 4 diverticular disease http://www.ebi.ac.uk/efo/EFO_0009959 GCST008257 Genome-wide genotyping array, Genome-wide sequencing 251377 2019-07-29 28585551 Sigurdsson S 2017-06-06 Nat Commun www.ncbi.nlm.nih.gov/pubmed/28585551 Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis. Diverticulitis 2,764 Icelandic ancestry cases, 245,951 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals) NA Illumina [32463443] (imputed) 10 diverticulitis http://www.ebi.ac.uk/efo/EFO_1001460 GCST008256 Genome-wide genotyping array, Genome-wide sequencing 248715 2019-06-26 28265093 Malik R 2017-03-06 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/28265093 Common coding variant in SERPINA1 increases the risk for large artery stroke. Large artery stroke up to 2,286 European ancestry cases, up to 376 South Asian cases, up to 8,884 European ancestry controls, up to 978 South Asian controls NA Illumina [92772] 8 large artery stroke http://www.ebi.ac.uk/efo/EFO_0005524 GCST007991 Exome genotyping array [Exome array] 12524 2018-07-19 29631575 Obeidat M 2018-04-10 Respir Res www.ncbi.nlm.nih.gov/pubmed/29631575 The genetics of smoking in individuals with chronic obstructive pulmonary disease. Cotinine levels in smokers with chronic obstructive pulmonary disease 4,024 European ancestry individuals NA Illumina [7807992] (imputed) 2 cotinine measurement http://www.ebi.ac.uk/efo/EFO_0007813 GCST005916 Genome-wide genotyping array 4024 2018-07-19 29631575 Obeidat M 2018-04-10 Respir Res www.ncbi.nlm.nih.gov/pubmed/29631575 The genetics of smoking in individuals with chronic obstructive pulmonary disease. Current cigarettes per day in chronic obstructive pulmonary disease 2,854 European ancestry individuals NA Illumina [7807992] (imputed) 2 cigarettes per day measurement http://www.ebi.ac.uk/efo/EFO_0006525 GCST005917 Genome-wide genotyping array 2854 2018-07-19 29631575 Obeidat M 2018-04-10 Respir Res www.ncbi.nlm.nih.gov/pubmed/29631575 The genetics of smoking in individuals with chronic obstructive pulmonary disease. Smoking cessation in chronic obstructive pulmonary disease 717 European ancestry sustained quitter cases, 2,175 European ancestry continuous smoker cases NA Illumina [7807992] (imputed) 2 smoking cessation http://www.ebi.ac.uk/efo/EFO_0004319 GCST005918 Genome-wide genotyping array 2892 2018-07-19 29631575 Obeidat M 2018-04-10 Respir Res www.ncbi.nlm.nih.gov/pubmed/29631575 The genetics of smoking in individuals with chronic obstructive pulmonary disease. Exhaled carbon monoxide levels in smokers with chronic obstructive pulmonary disease 2,706 European ancestry individuals NA Illumina [7807992] (imputed) 3 carbon monoxide exhalation measurement http://www.ebi.ac.uk/efo/EFO_0006520 GCST005919 Genome-wide genotyping array 2706 2020-09-12 32835660 Shin JG 2020-08-21 J Invest Dermatol www.ncbi.nlm.nih.gov/pubmed/32835660 Genome-wide association analysis of 17,019 Korean women identifies variants associated with facial pigmented spots. Facial pigmentation measurement (UV light) 11,079 Korean women 5,940 Korean women Illumina [366864] (imputed) 7 facial pigmentation measurement http://www.ebi.ac.uk/efo/EFO_0006942 GCST90002283 Genome-wide genotyping array 11079 2020-09-12 32835660 Shin JG 2020-08-21 J Invest Dermatol www.ncbi.nlm.nih.gov/pubmed/32835660 Genome-wide association analysis of 17,019 Korean women identifies variants associated with facial pigmented spots. Facial pigmentation measurement (polar light) 11,079 Korean women 5,940 Korean women Illumina [366864] (imputed) 7 facial pigmentation measurement http://www.ebi.ac.uk/efo/EFO_0006942 GCST90002284 Genome-wide genotyping array 11079 2019-02-28 30254083 Cousminer DL 2018-09-25 Diabetes Care www.ncbi.nlm.nih.gov/pubmed/30254083 First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes. Latent autoimmune diabetes 2,634 European ancestry cases, 5,947 European ancestry controls 345 European ancestry cases, 1,664 European ancestry controls Affymetrix, Illumina [7868002] (imputed) 3 latent autoimmune diabetes in adults http://www.ebi.ac.uk/efo/EFO_0009706 GCST007245 Genome-wide genotyping array 8581 2019-02-28 30254083 Cousminer DL 2018-09-25 Diabetes Care www.ncbi.nlm.nih.gov/pubmed/30254083 First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes. Latent autoimmune diabetes vs. type 2 diabetes 2,779 European ancestry latent autoimmune diabetes cases, 10,396 European ancestry type 2 diabetes cases NA Affymetrix, Illumina [8328843] (imputed) 4 latent autoimmune diabetes in adults, type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0009706, http://www.ebi.ac.uk/efo/EFO_0001360 GCST007246 Genome-wide genotyping array 13177 2019-02-28 30254083 Cousminer DL 2018-09-25 Diabetes Care www.ncbi.nlm.nih.gov/pubmed/30254083 First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes. Latent autoimmune diabetes vs. type 1 diabetes 2,454 European ancestry latent autoimmune diabetes cases, 968 European ancestry type 1 diabetes cases NA Affymetrix, Illumina [8465706] (imputed) 1 type I diabetes mellitus, latent autoimmune diabetes in adults http://www.ebi.ac.uk/efo/EFO_0001359, http://www.ebi.ac.uk/efo/EFO_0009706 GCST007247 Genome-wide genotyping array 3423 2018-11-01 30061609 Wyss AB 2018-07-30 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30061609 Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function. Lung function (FEV1) 60,552 European ancestry individuals, 8,429 African individuals, 9,959 Korean ancestry individuals, 11,775 Hispanic individuals NA Affymetrix, Illumina [10900000] (imputed) 56 forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0004314 GCST006481 Genome-wide genotyping array 90715 2018-11-01 30061609 Wyss AB 2018-07-30 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30061609 Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function. Lung function (FEV1/FVC) 60,552 European ancestry individuals, 8,429 African individuals, 9,959 Korean ancestry individuals, 11,775 Hispanic individuals NA Affymetrix, Illumina [10900000] (imputed) 39 FEV/FEC ratio http://www.ebi.ac.uk/efo/EFO_0004713 GCST006482 Genome-wide genotyping array 90715 2018-11-01 30061609 Wyss AB 2018-07-30 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30061609 Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function. Lung function (FVC) 60,552 European ancestry individuals, 8,429 African individuals, 9,959 Korean ancestry individuals, 11,775 Hispanic individuals NA Affymetrix, Illumina [10900000] (imputed) 69 vital capacity http://www.ebi.ac.uk/efo/EFO_0004312 GCST006483 Genome-wide genotyping array 90715 2019-04-29 30255771 Sarnowski C 2018-09-17 BMC Genet www.ncbi.nlm.nih.gov/pubmed/30255771 Investigation of parent-of-origin effects induced by fenofibrate treatment on triglycerides levels. Triglyceride levels (parental genotype effect) 173 European ancestry families NA Affymetrix [715787] 7 triglyceride measurement, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0005939 GCST007658 Genome-wide genotyping array 173 2019-04-29 30255771 Sarnowski C 2018-09-17 BMC Genet www.ncbi.nlm.nih.gov/pubmed/30255771 Investigation of parent-of-origin effects induced by fenofibrate treatment on triglycerides levels. Triglyceride levels in response to fenofibrate treatment (parental genotype effect) 173 European ancestry families NA Affymetrix [715787] 3 triglyceride measurement, response to fenofibrate, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0004530, http://purl.obolibrary.org/obo/GO_1901557, http://www.ebi.ac.uk/efo/EFO_0005939 GCST007660 Genome-wide genotyping array 173 2019-04-29 30255771 Sarnowski C 2018-09-17 BMC Genet www.ncbi.nlm.nih.gov/pubmed/30255771 Investigation of parent-of-origin effects induced by fenofibrate treatment on triglycerides levels. Triglyceride change in response to fenofibrate (parental genotype effect) 173 European ancestry families NA Affymetrix [715787] 0 triglyceride change measurement, response to fenofibrate, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0007681, http://purl.obolibrary.org/obo/GO_1901557, http://www.ebi.ac.uk/efo/EFO_0005939 GCST007659 Genome-wide genotyping array 173 2019-04-29 30255771 Sarnowski C 2018-09-17 BMC Genet www.ncbi.nlm.nih.gov/pubmed/30255771 Investigation of parent-of-origin effects induced by fenofibrate treatment on triglycerides levels. Triglyceride levels 173 European ancestry families NA Affymetrix [715787] 1 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST007661 Genome-wide genotyping array 173 2019-04-29 30255771 Sarnowski C 2018-09-17 BMC Genet www.ncbi.nlm.nih.gov/pubmed/30255771 Investigation of parent-of-origin effects induced by fenofibrate treatment on triglycerides levels. Triglyceride levels in response to fenofibrate 173 European ancestry families NA Affymetrix [715787] 0 triglyceride measurement, response to fenofibrate http://www.ebi.ac.uk/efo/EFO_0004530, http://purl.obolibrary.org/obo/GO_1901557 GCST007662 Genome-wide genotyping array 173 2019-04-29 30255771 Sarnowski C 2018-09-17 BMC Genet www.ncbi.nlm.nih.gov/pubmed/30255771 Investigation of parent-of-origin effects induced by fenofibrate treatment on triglycerides levels. Triglyceride change in response to fenofibrate treatment 173 European ancestry families NA Affymetrix [715787] 0 triglyceride change measurement, response to fenofibrate http://www.ebi.ac.uk/efo/EFO_0007681, http://purl.obolibrary.org/obo/GO_1901557 GCST007663 Genome-wide genotyping array 173 2018-12-05 30263053 Deng X 2018-09-17 BMC Proc www.ncbi.nlm.nih.gov/pubmed/30263053 Genome-wide association study for multiple phenotype analysis. Triglyceride levels 821 individuals NA Affymetrix [587358] 2 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST006664 Genome-wide genotyping array 821 2018-12-05 30263053 Deng X 2018-09-17 BMC Proc www.ncbi.nlm.nih.gov/pubmed/30263053 Genome-wide association study for multiple phenotype analysis. HDL cholesterol 821 individuals NA Affymetrix [587358] 4 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST006663 Genome-wide genotyping array 821 2018-12-06 30263053 Deng X 2018-09-17 BMC Proc www.ncbi.nlm.nih.gov/pubmed/30263053 Genome-wide association study for multiple phenotype analysis. HDL cholesterol and triglyceride levels (pleiotropy) 821 individuals NA Affymetrix [587358] 8 triglyceride measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0004612 GCST006669 Genome-wide genotyping array 821 2019-02-14 30265060 MacKillop J 2018-09-27 Exp Clin Psychopharmacol www.ncbi.nlm.nih.gov/pubmed/30265060 Genetic influences on delayed reward discounting: A genome-wide prioritized subset approach. Delayed reward discounting 986 European ancestry individuals NA Illumina [4883968] (imputed) 5 delayed reward discounting measurement http://www.ebi.ac.uk/efo/EFO_0008476 GCST007153 Genome-wide genotyping array 986 2019-02-14 30266756 Chang X 2018-09-28 J Med Genet www.ncbi.nlm.nih.gov/pubmed/30266756 Common variants at 5q33.1 predispose to migraine in African-American children. Paediatric migraine 380 African American cases, 2,129 African American controls, 599 European American cases, 7,327 European American controls 233 African American cases, 4,038 African American controls Illumina [up to 522471] 2 migraine disorder http://www.ebi.ac.uk/efo/EFO_0003821 GCST007154 Genome-wide genotyping array 10435 2020-10-08 32790701 Rode M 2020-08-13 PLoS One www.ncbi.nlm.nih.gov/pubmed/32790701 Genome-wide association analysis of pulse wave velocity traits provide new insights into the causal relationship between arterial stiffness and blood pressure. Arterial stiffness (carotid-femoral pulse wave velocity) 6,430 European ancestry individuals NA Affymetrix [11342744] (imputed) 2 arterial stiffness measurement http://www.ebi.ac.uk/efo/EFO_0004517 GCST010655 Genome-wide genotyping array 6430 2020-10-08 32790701 Rode M 2020-08-13 PLoS One www.ncbi.nlm.nih.gov/pubmed/32790701 Genome-wide association analysis of pulse wave velocity traits provide new insights into the causal relationship between arterial stiffness and blood pressure. Arterial stiffness (brachial-femoral pulse wave velocity) 3,643 European ancestry individuals NA Affymetrix [11342744] (imputed) 5 arterial stiffness measurement http://www.ebi.ac.uk/efo/EFO_0004517 GCST010654 Genome-wide genotyping array 3643 2020-10-08 32790701 Rode M 2020-08-13 PLoS One www.ncbi.nlm.nih.gov/pubmed/32790701 Genome-wide association analysis of pulse wave velocity traits provide new insights into the causal relationship between arterial stiffness and blood pressure. Arterial stiffness (brachial-ankle pulse wave velocity) 6,734 European ancestry individuals NA Affymetrix [11342744] (imputed) 3 arterial stiffness measurement http://www.ebi.ac.uk/efo/EFO_0004517 GCST010656 Genome-wide genotyping array 6734 2020-07-23 32499652 Asgari S 2020-05-13 Nature www.ncbi.nlm.nih.gov/pubmed/32499652 A positively selected FBN1 missense variant reduces height in Peruvian individuals. Height 598 Peruvian individuals NA Illumina [NR] 0 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST010311 Genome-wide genotyping array 598 2020-07-23 32499652 Asgari S 2020-05-13 Nature www.ncbi.nlm.nih.gov/pubmed/32499652 A positively selected FBN1 missense variant reduces height in Peruvian individuals. Height 3,134 Peruvian individuals 598 Peruvian individuals Affymetrix [7756401] (imputed) 1 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST90002224 Genome-wide genotyping array 3134 2021-03-30 32808324 Hu J 2020-08-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/32808324 Supervariants identification for breast cancer. Breast cancer 5,653 cases, 28,241 controls NA NR [41502298] (imputed) 8 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST011433 Genome-wide genotyping array 33894 2021-03-30 32811377 Dueker ND 2020-08-19 Stroke www.ncbi.nlm.nih.gov/pubmed/32811377 Extreme Phenotype Approach Suggests Taste Transduction Pathway for Carotid Plaque in a Multi-Ethnic Cohort. Total carotid plaque area (excess vs minimal atherosclerosis) 180 Hispanic individuals, 100 Black individuals, 60 European ancestry individuals NA Affymetrix [NR] (imputed) 3 carotid plaque build http://www.ebi.ac.uk/efo/EFO_0006501 GCST011436 Genome-wide genotyping array 340 2020-09-14 32451486 Zhou H 2020-05-25 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/32451486 Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits. Alcohol use disorder 57,564 European ancestry cases, 256,395 European ancestry controls NA Affymetrix [7003540] (imputed) 26 alcohol use disorder measurement http://www.ebi.ac.uk/efo/EFO_0009458 GCST010545 Genome-wide genotyping array 313959 2020-09-14 32451486 Zhou H 2020-05-25 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/32451486 Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits. Problematic alcohol use (MTAG) 972,915 European ancestry individuals NA Affymetrix [10613246] (imputed) 76 alcohol use disorder measurement, alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0009458, http://www.ebi.ac.uk/efo/EFO_0007878 GCST010544 Genome-wide genotyping array 972915 2020-09-14 32451486 Zhou H 2020-05-25 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/32451486 Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits. Alcohol consumption (drinks per week) (MTAG) 972,915 European ancestry individuals NA Affymetrix [NR] (imputed) 86 alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0007878 GCST010543 Genome-wide genotyping array 972915 2020-09-14 32451486 Zhou H 2020-05-25 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/32451486 Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits. Problematic alcohol use 435,563 European ancestry individuals NA Affymetrix [14069427] (imputed) 32 alcohol use disorder measurement http://www.ebi.ac.uk/efo/EFO_0009458 GCST010546 Genome-wide genotyping array 435563 2021-03-30 33692830 Indencleef K 2021-02-22 Front Genet www.ncbi.nlm.nih.gov/pubmed/33692830 The Intersection of the Genetic Architectures of Orofacial Clefts and Normal Facial Variation. Facial morphology traits (59 NSCL/P endophenotypic segments) 8,246 European ancestry individuals NA NR [7417619] (imputed) 36 facial morphology measurement http://www.ebi.ac.uk/efo/EFO_0007841 GCST011429 Genome-wide genotyping array 8246 2021-03-30 32826979 Meguro A 2020-08-21 Commun Biol www.ncbi.nlm.nih.gov/pubmed/32826979 Genetic control of CCL24, POR, and IL23R contributes to the pathogenesis of sarcoidosis. Sarcoidosis 685 Japanese ancestry cases, 847 Japanese ancestry controls 907 Japanese ancestry cases, 252 European ancestry cases, 1,042 Japanese ancestry controls, 256 European ancestry controls Illumina [530466] (imputed) 4 Sarcoidosis http://www.orpha.net/ORDO/Orphanet_797 GCST011437 Genome-wide genotyping array 1532 2021-07-09 32814349 Jager R 2020-08-19 Blood www.ncbi.nlm.nih.gov/pubmed/32814349 Germline Genetic Factors Influence Outcome of Interferon Alpha Therapy in Polycythemia Vera. response to ropeginterferon alfa-2b in polycythemia vera 122 individuals 27 individuals Affymetrix [NR] 0 response to ropeginterferon alfa-2b http://www.ebi.ac.uk/efo/EFO_0600013 GCST012018 Genome-wide genotyping array 122 2020-10-06 29715290 Traylor M 2018-05-01 PLoS One www.ncbi.nlm.nih.gov/pubmed/29715290 Exome array analysis of adverse reactions to fluoropyrimidine-based therapy for gastrointestinal cancer. Adverse response to chemotherapy (fluoropyrimidines) 504 European ancestry cases NA Illumina [59277] 0 response to fluoropyrimidines http://www.ebi.ac.uk/efo/EFO_0010825 GCST010639 Exome genotyping array [Exome array] 504 2020-10-07 32606422 Wu Y 2020-06-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32606422 Multi-trait analysis for genome-wide association study of five psychiatric disorders. Autism spectrum disorder (MTAG) 60,817 individuals NA NR [520857] 10 autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0003756 GCST010643 Genome-wide genotyping array 60817 2020-10-07 32606422 Wu Y 2020-06-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32606422 Multi-trait analysis for genome-wide association study of five psychiatric disorders. Depressive symptoms (MTAG) 955,012 individuals NA NR [520857] 63 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST010642 Genome-wide genotyping array 955012 2020-10-07 32606422 Wu Y 2020-06-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32606422 Multi-trait analysis for genome-wide association study of five psychiatric disorders. Bipolar disorder (MTAG) 65,682 individuals NA NR [520857] 63 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST010641 Genome-wide genotyping array 65682 2020-10-07 32606422 Wu Y 2020-06-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32606422 Multi-trait analysis for genome-wide association study of five psychiatric disorders. Schizophrenia (MTAG) 67,764 individuals NA NR [8377093] 110 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST010640 Genome-wide genotyping array 67764 2020-10-07 32606422 Wu Y 2020-06-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32606422 Multi-trait analysis for genome-wide association study of five psychiatric disorders. Attention deficit hyperactivity disorder 55,374 individuals NA NR [8028859] 15 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST010649 Genome-wide genotyping array 55374 2020-10-07 32606422 Wu Y 2020-06-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32606422 Multi-trait analysis for genome-wide association study of five psychiatric disorders. Attention deficit hyperactivity disorder (MTAG) 61,421 individuals NA NR [520857] 21 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST010644 Genome-wide genotyping array 61421 2020-10-07 32606422 Wu Y 2020-06-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32606422 Multi-trait analysis for genome-wide association study of five psychiatric disorders. Autism spectrum disorder 46,350 individuals NA NR [9087710] 3 autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0003756 GCST010648 Genome-wide genotyping array 46350 2020-10-07 32606422 Wu Y 2020-06-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32606422 Multi-trait analysis for genome-wide association study of five psychiatric disorders. Depressive symptoms 688,809 individuals NA NR [11140414] 49 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST010647 Genome-wide genotyping array 688809 2020-10-07 32606422 Wu Y 2020-06-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32606422 Multi-trait analysis for genome-wide association study of five psychiatric disorders. Bipolar disorder 41,653 individuals NA NR [8956949] 8 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST010646 Genome-wide genotyping array 41653 2020-10-07 32606422 Wu Y 2020-06-30 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32606422 Multi-trait analysis for genome-wide association study of five psychiatric disorders. Schizophrenia (MTAG) 65,967 individuals NA NR [8377093] 87 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST010645 Genome-wide genotyping array 65967 2020-10-27 32374345 Turley TN 2020-05-06 JAMA Cardiol www.ncbi.nlm.nih.gov/pubmed/32374345 Identification of Susceptibility Loci for Spontaneous Coronary Artery Dissection. Spontaneous coronary artery dissection 484 European ancestry cases, 1,477 European ancestry controls 183 European ancestry cases, 340 European ancestry controls Illumina [~ 5000000] (imputed) 7 spontaneous coronary artery dissection http://www.ebi.ac.uk/efo/EFO_0010820 GCST010722 Genome-wide genotyping array 1961 2020-10-08 32912094 Jaworek T 2020-09-11 Stroke www.ncbi.nlm.nih.gov/pubmed/32912094 Exome Array Analysis of Early-Onset Ischemic Stroke. Early-onset ischemic stroke 330 African American cases, 393 European ancestry cases, 298 African American controls, 428 European ancestry controls NA Illumina [243497] 3 Ischemic stroke http://purl.obolibrary.org/obo/HP_0002140 GCST010652 Exome genotyping array [Exome array] 1449 2020-10-15 32289280 Zhang Y 2020-04-11 Am J Obstet Gynecol www.ncbi.nlm.nih.gov/pubmed/32289280 A genome-wide association study of polycystic ovary syndrome identified from electronic health records. Polycystic ovary syndrome 1,735 European ancestry cases, 1,007 European, African American and unknown ancestry cases, 27,812 European ancestry controls, 23,626 European, African American and unknown ancestry controls 253 European ancestry cases, 2,161 European ancestry controls NR [at least 5648769] (imputed) 5 polycystic ovary syndrome http://www.ebi.ac.uk/efo/EFO_0000660 GCST010687 Genome-wide genotyping array 54180 2021-05-26 32928300 Sugino S 2020-09-14 Hum Genomics www.ncbi.nlm.nih.gov/pubmed/32928300 Long non-coding RNA MIR4300HG polymorphisms are associated with postoperative nausea and vomiting: a genome-wide association study. Postoperative nausea and vomiting 12 Japanese ancestry cases, 12 Japanese ancestry controls 46 Japanese ancestry cases, 186 Japanese ancestry controls NR [6714496] (imputed) 0 post operative nausea and vomiting http://www.ebi.ac.uk/efo/EFO_0004888 GCST011738 Genome-wide genotyping array 24 2021-02-03 32599975 Bae JS 2020-06-30 Cancer Res Treat www.ncbi.nlm.nih.gov/pubmed/32599975 Genome-Wide Association Study for the Identification of Novel Genetic Variants Associated with the Risk of Neuroblastoma in Korean Children. Neuroblastoma (pediatric) 296 Korean ancestry child cases, 1,000 Korean ancestry adult controls NA Illumina [NR] (imputed) 14 neuroblastoma http://www.ebi.ac.uk/efo/EFO_0000621 GCST011053 Genome-wide genotyping array 1296 2020-10-14 32690583 Cheng B 2020-07-20 G3 (Bethesda) www.ncbi.nlm.nih.gov/pubmed/32690583 Genome-Wide Association Analysis Identified ANXA1 Associated with Shoulder Impingement Syndrome in UK Biobank Samples. Shoulder impingement syndrome 7,252 European ancestry individuals NA Affymetrix [825927] (imputed) 20 shoulder impingement syndrome http://www.ebi.ac.uk/efo/EFO_1001178 GCST90010423 Genome-wide genotyping array 7252 2021-05-10 32998964 Trendowski MR 2020-09-30 Clin Cancer Res www.ncbi.nlm.nih.gov/pubmed/32998964 Clinical and Genome-Wide Analysis of Multiple Severe Cisplatin-Induced Neurotoxicities in Adult-Onset Cancer Survivors. Multiple severe cisplatin-induced neurotixicitiies in testicular cancer survivors 104 European ancestry cases, 196 European ancestry controls NA Illumina [5385324] (imputed) 5 response to cisplatin http://purl.obolibrary.org/obo/GO_0072718 GCST011637 Genome-wide genotyping array 300 2021-03-12 33021770 Freidin MB 2020-09-30 Pain www.ncbi.nlm.nih.gov/pubmed/33021770 Sex- and age-specific genetic analysis of chronic back pain. Chronic back pain 35,705 European ancestry male cases, 166,372 European ancestry male controls 10,723 European ancestry male cases, 33,017 European ancestry male controls Affymetrix [14828942] (imputed) 0 Back pain http://purl.obolibrary.org/obo/HP_0003418 GCST011262 Genome-wide genotyping array 202077 2021-03-12 33021770 Freidin MB 2020-09-30 Pain www.ncbi.nlm.nih.gov/pubmed/33021770 Sex- and age-specific genetic analysis of chronic back pain. Chronic back pain 7,758 European ancestry male cases, 36,074 European ancestry male controls NA Affymetrix [14828942] (imputed) 0 Back pain http://purl.obolibrary.org/obo/HP_0003418 GCST011261 Genome-wide genotyping array 43832 2021-03-12 33021770 Freidin MB 2020-09-30 Pain www.ncbi.nlm.nih.gov/pubmed/33021770 Sex- and age-specific genetic analysis of chronic back pain. Chronic back pain 28,009 European ancestry male cases, 130,236 European ancestry male controls NA Affymetrix [14828942] (imputed) 0 Back pain http://purl.obolibrary.org/obo/HP_0003418 GCST011260 Genome-wide genotyping array 158245 2021-03-12 33021770 Freidin MB 2020-09-30 Pain www.ncbi.nlm.nih.gov/pubmed/33021770 Sex- and age-specific genetic analysis of chronic back pain. Chronic back pain 43,230 European ancestry female cases, 194,524 European ancestry female controls 15,139 European ancestry female cases, 34,926 European ancestry female controls Affymetrix [14828942] (imputed) 0 Back pain http://purl.obolibrary.org/obo/HP_0003418 GCST011259 Genome-wide genotyping array 237754 2021-03-12 33021770 Freidin MB 2020-09-30 Pain www.ncbi.nlm.nih.gov/pubmed/33021770 Sex- and age-specific genetic analysis of chronic back pain. Chronic back pain 8,987 European ancestry female cases, 35,502 European ancestry female controls NA Affymetrix [14828942] (imputed) 0 Back pain http://purl.obolibrary.org/obo/HP_0003418 GCST011258 Genome-wide genotyping array 44489 2021-03-12 33021770 Freidin MB 2020-09-30 Pain www.ncbi.nlm.nih.gov/pubmed/33021770 Sex- and age-specific genetic analysis of chronic back pain. Chronic back pain 34,207 European ancestry female cases, 159,058 European ancestry female controls NA Affymetrix [14828942] (imputed) 0 Back pain http://purl.obolibrary.org/obo/HP_0003418 GCST011257 Genome-wide genotyping array 193265 2021-03-26 33017352 Kim SK 2020-10-01 Med Sci Sports Exerc www.ncbi.nlm.nih.gov/pubmed/33017352 A Genome-wide Association Study for Concussion Risk. Concussion 4,064 European ancestry cases, 291,472 European ancestry controls NA Affymetrix [7743986] (imputed) 2 concussion http://www.ebi.ac.uk/efo/EFO_0011023 GCST011408 Genome-wide genotyping array 295536 2020-11-12 32805626 Yuan S 2020-08-14 EBioMedicine www.ncbi.nlm.nih.gov/pubmed/32805626 Effects of tumour necrosis factor on cardiovascular disease and cancer: A two-sample Mendelian randomization study. Tumor necrosis factor levels 30,912 European ancestry individuals NA NR [NR] 4 tumor necrosis factor measurement http://www.ebi.ac.uk/efo/EFO_0010834 GCST010738 Genome-wide genotyping array 30912 2021-03-24 32723796 Mehta SD 2020-07-28 mSystems www.ncbi.nlm.nih.gov/pubmed/32723796 Host Genetic Factors Associated with Vaginal Microbiome Composition in Kenyan Women. Vaginal microbiome composition (L. iners) 171 Kenyan ancestry individuals NA Illumina [336151] (imputed) 4 vaginal microbiome measurement http://www.ebi.ac.uk/efo/EFO_0011013 GCST011387 Genome-wide genotyping array 171 2021-03-24 32723796 Mehta SD 2020-07-28 mSystems www.ncbi.nlm.nih.gov/pubmed/32723796 Host Genetic Factors Associated with Vaginal Microbiome Composition in Kenyan Women. Vaginal microbiome composition (G. vaginalis) 171 Kenyan ancestry individuals NA Illumina [336151] (imputed) 2 vaginal microbiome measurement http://www.ebi.ac.uk/efo/EFO_0011013 GCST011386 Genome-wide genotyping array 171 2021-03-24 32723796 Mehta SD 2020-07-28 mSystems www.ncbi.nlm.nih.gov/pubmed/32723796 Host Genetic Factors Associated with Vaginal Microbiome Composition in Kenyan Women. Vaginal microbiome composition (Shannon diversity index) 171 Kenyan ancestry individuals NA Illumina [336151] (imputed) 6 vaginal microbiome measurement http://www.ebi.ac.uk/efo/EFO_0011013 GCST011385 Genome-wide genotyping array 171 2021-03-24 32723796 Mehta SD 2020-07-28 mSystems www.ncbi.nlm.nih.gov/pubmed/32723796 Host Genetic Factors Associated with Vaginal Microbiome Composition in Kenyan Women. Vaginal microbiome composition (community state type) 171 Kenyan ancestry individuals NA Illumina [336151] (imputed) 3 vaginal microbiome measurement http://www.ebi.ac.uk/efo/EFO_0011013 GCST011384 Genome-wide genotyping array 171 2021-03-24 32723796 Mehta SD 2020-07-28 mSystems www.ncbi.nlm.nih.gov/pubmed/32723796 Host Genetic Factors Associated with Vaginal Microbiome Composition in Kenyan Women. Vaginal microbiome composition (L. crispatus) 42 Kenyan ancestry cases, 129 Kenyan ancestry controls NA Illumina [336151] (imputed) 1 vaginal microbiome measurement http://www.ebi.ac.uk/efo/EFO_0011013 GCST011388 Genome-wide genotyping array 171 2021-03-22 32756886 Nunez-Torres R 2020-08-05 JAMA Dermatol www.ncbi.nlm.nih.gov/pubmed/32756886 Association Between ABCB1 Genetic Variants and Persistent Chemotherapy-Induced Alopecia in Women With Breast Cancer. Persistent chemotherapy-induced alopecia in breast cancer 51 European ancestry cases, 122 European ancestry controls 20 European ancestry cases, 22 European ancestry controls Illumina [693898] 1 chemotherapy-induced alopecia, response to docetaxel http://www.ebi.ac.uk/efo/EFO_0005400, http://purl.obolibrary.org/obo/GO_1902519 GCST011316 Genome-wide genotyping array 173 2020-09-07 32814899 Meyer HV 2020-08-19 Nature www.ncbi.nlm.nih.gov/pubmed/32814899 Genetic and functional insights into the fractal structure of the heart. Myocardial fractal dimension (slice 1) 18,096 European individuals NA Affymetrix [14134301] (imputed) 0 left ventricular structural measurement http://www.ebi.ac.uk/efo/EFO_0008205 GCST90000287 Genome-wide genotyping array 18096 2020-09-07 32814899 Meyer HV 2020-08-19 Nature www.ncbi.nlm.nih.gov/pubmed/32814899 Genetic and functional insights into the fractal structure of the heart. Myocardial fractal dimension (slice 2) 18,096 European individuals NA Affymetrix [14134301] (imputed) 5 left ventricular structural measurement http://www.ebi.ac.uk/efo/EFO_0008205 GCST90000288 Genome-wide genotyping array 18096 2020-09-07 32814899 Meyer HV 2020-08-19 Nature www.ncbi.nlm.nih.gov/pubmed/32814899 Genetic and functional insights into the fractal structure of the heart. Myocardial fractal dimension (slice 3) 18,096 European individuals NA Affymetrix [14134301] (imputed) 8 left ventricular structural measurement http://www.ebi.ac.uk/efo/EFO_0008205 GCST90000289 Genome-wide genotyping array 18096 2020-09-07 32814899 Meyer HV 2020-08-19 Nature www.ncbi.nlm.nih.gov/pubmed/32814899 Genetic and functional insights into the fractal structure of the heart. Myocardial fractal dimension (slice 4) 18,096 European individuals NA Affymetrix [14134301] (imputed) 9 left ventricular structural measurement http://www.ebi.ac.uk/efo/EFO_0008205 GCST90000290 Genome-wide genotyping array 18096 2020-09-07 32814899 Meyer HV 2020-08-19 Nature www.ncbi.nlm.nih.gov/pubmed/32814899 Genetic and functional insights into the fractal structure of the heart. Myocardial fractal dimension (slice 5) 18,096 European individuals NA Affymetrix [14134301] (imputed) 9 left ventricular structural measurement http://www.ebi.ac.uk/efo/EFO_0008205 GCST90000291 Genome-wide genotyping array 18096 2020-09-07 32814899 Meyer HV 2020-08-19 Nature www.ncbi.nlm.nih.gov/pubmed/32814899 Genetic and functional insights into the fractal structure of the heart. Myocardial fractal dimension (slice 6) 18,096 European individuals NA Affymetrix [14134301] (imputed) 11 left ventricular structural measurement http://www.ebi.ac.uk/efo/EFO_0008205 GCST90000292 Genome-wide genotyping array 18096 2020-09-07 32814899 Meyer HV 2020-08-19 Nature www.ncbi.nlm.nih.gov/pubmed/32814899 Genetic and functional insights into the fractal structure of the heart. Myocardial fractal dimension (slice 7) 18,096 European individuals NA Affymetrix [14134301] (imputed) 8 left ventricular structural measurement http://www.ebi.ac.uk/efo/EFO_0008205 GCST90000293 Genome-wide genotyping array 18096 2020-09-07 32814899 Meyer HV 2020-08-19 Nature www.ncbi.nlm.nih.gov/pubmed/32814899 Genetic and functional insights into the fractal structure of the heart. Myocardial fractal dimension (slice 8) 18,096 European individuals NA Affymetrix [14134301] (imputed) 6 left ventricular structural measurement http://www.ebi.ac.uk/efo/EFO_0008205 GCST90000294 Genome-wide genotyping array 18096 2020-09-07 32814899 Meyer HV 2020-08-19 Nature www.ncbi.nlm.nih.gov/pubmed/32814899 Genetic and functional insights into the fractal structure of the heart. Myocardial fractal dimension (slice 9) 18,096 European individuals NA Affymetrix [14134301] (imputed) 2 left ventricular structural measurement http://www.ebi.ac.uk/efo/EFO_0008205 GCST90000295 Genome-wide genotyping array 18096 2020-09-07 32814899 Meyer HV 2020-08-19 Nature www.ncbi.nlm.nih.gov/pubmed/32814899 Genetic and functional insights into the fractal structure of the heart. Myocardial fractal dimension (slices 1-9) 18,096 European individuals NA Affymetrix [14134301] (imputed) 0 left ventricular structural measurement http://www.ebi.ac.uk/efo/EFO_0008205 GCST90000296 Genome-wide genotyping array 18096 2020-12-09 32298765 Anstee QM 2020-04-13 J Hepatol www.ncbi.nlm.nih.gov/pubmed/32298765 Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically-characterised cohort. Hepatic steatosis in non-alcoholic fatty liver disease 1,469 European ancestry individuals 504 European ancestry individuals Illumina [7412561] (imputed) 0 Hepatic steatosis http://purl.obolibrary.org/obo/HP_0001397 GCST010858 Genome-wide genotyping array 1469 2020-12-10 32298765 Anstee QM 2020-04-13 J Hepatol www.ncbi.nlm.nih.gov/pubmed/32298765 Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically-characterised cohort. Liver fibrosis in non-alcoholic fatty liver disease 1,481 European ancestry individuals 557 European ancestry individuals Illumina [7412560] (imputed) 0 liver fibrosis measurement http://www.ebi.ac.uk/efo/EFO_0010576 GCST010864 Genome-wide genotyping array 1481 2020-12-10 32298765 Anstee QM 2020-04-13 J Hepatol www.ncbi.nlm.nih.gov/pubmed/32298765 Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically-characterised cohort. Non-alcoholic steatohepatitis activity score in non-alcoholic fatty liver disease 1,467 European ancestry individuals 501 European ancestry individuals Illumina [7412560] (imputed) 0 non-alcoholic fatty liver disease severity measurement http://www.ebi.ac.uk/efo/EFO_0008421 GCST010863 Genome-wide genotyping array 1467 2020-12-10 32298765 Anstee QM 2020-04-13 J Hepatol www.ncbi.nlm.nih.gov/pubmed/32298765 Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically-characterised cohort. Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease 1,467 European ancestry individuals 501 European ancestry individuals Illumina [7412560] (imputed) 0 non-alcoholic fatty liver disease severity measurement http://www.ebi.ac.uk/efo/EFO_0008421 GCST010862 Genome-wide genotyping array 1467 2020-12-10 32298765 Anstee QM 2020-04-13 J Hepatol www.ncbi.nlm.nih.gov/pubmed/32298765 Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically-characterised cohort. Nonalcoholic steatohepatitis 836 European ancestry cases, 17,781 European ancestry controls NA Illumina [7412560] (imputed) 8 non-alcoholic steatohepatitis http://www.ebi.ac.uk/efo/EFO_1001249 GCST010861 Genome-wide genotyping array 18617 2020-12-10 32298765 Anstee QM 2020-04-13 J Hepatol www.ncbi.nlm.nih.gov/pubmed/32298765 Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically-characterised cohort. Severe liver fibrosis and non-alcoholic fatty liver disease 386 European ancestry cases, 17,781 European ancestry controls 134 European ancestry cases, 945 European ancestry controls Illumina [7412560] (imputed) 0 non-alcoholic fatty liver disease, Hepatic fibrosis, liver fibrosis measurement http://www.ebi.ac.uk/efo/EFO_0003095, http://purl.obolibrary.org/obo/HP_0001395, http://www.ebi.ac.uk/efo/EFO_0010576 GCST010860 Genome-wide genotyping array 18167 2020-12-09 32298765 Anstee QM 2020-04-13 J Hepatol www.ncbi.nlm.nih.gov/pubmed/32298765 Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically-characterised cohort. Nonalcoholic fatty liver disease 1,483 European ancestry cases, 17,781 European ancestry controls 559 European ancestry cases, 945 European ancestry controls Illumina [7412560] (imputed) 2 non-alcoholic fatty liver disease http://www.ebi.ac.uk/efo/EFO_0003095 GCST90011885 Genome-wide genotyping array 19264 2021-03-30 32824824 Diaz-Pena R 2020-08-18 J Pers Med www.ncbi.nlm.nih.gov/pubmed/32824824 Amerindian Ancestry Influences Genetic Susceptibility to Chronic Obstructive Pulmonary Disease. Chronic obstructive pulmonary disease 214 Chilean cases, 193 Chilean controls NA Illumina [754159] (imputed) 3 chronic obstructive pulmonary disease http://www.ebi.ac.uk/efo/EFO_0000341 GCST011435 Genome-wide genotyping array 407 2021-03-24 32844198 Dumitrescu L 2020-08-01 Brain www.ncbi.nlm.nih.gov/pubmed/32844198 Genetic variants and functional pathways associated with resilience to Alzheimer's disease. Combined resilience (covariance of educational attainment with residual cognitive resilience) 5,108 European ancestry individuals (unimpaired cognition, mild cognitive impairment or Alzheimer’s disease) NA Affymetrix, Illumina [4840740] (imputed) 7 cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0008354 GCST011405 Genome-wide genotyping array 5108 2021-03-24 32844198 Dumitrescu L 2020-08-01 Brain www.ncbi.nlm.nih.gov/pubmed/32844198 Genetic variants and functional pathways associated with resilience to Alzheimer's disease. Residual cognitive resilience 5,108 European ancestry individuals (unimpaired cognition, mild cognitive impairment or Alzheimer’s disease) NA Affymetrix, Illumina [4840740] (imputed) 9 cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0008354 GCST011406 Genome-wide genotyping array 5108 2021-03-24 32844198 Dumitrescu L 2020-08-01 Brain www.ncbi.nlm.nih.gov/pubmed/32844198 Genetic variants and functional pathways associated with resilience to Alzheimer's disease. Residual cognitive resilience 3,820 European ancestry cognitively unimpaired individuals NA Affymetrix, Illumina [4840740] (imputed) 8 cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0008354 GCST011404 Genome-wide genotyping array 3820 2021-03-24 32844198 Dumitrescu L 2020-08-01 Brain www.ncbi.nlm.nih.gov/pubmed/32844198 Genetic variants and functional pathways associated with resilience to Alzheimer's disease. Combined resilience (covariance of educational attainment with residual cognitive resilience) 3,820 European ancestry cognitively unimpaired individuals NA Affymetrix, Illumina [4840740] (imputed) 14 cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0008354 GCST011403 Genome-wide genotyping array 3820 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels 56,802 European ancestry, African American or Afro-Caribbean, East Asian ancestry, Hispanic or Latin American individuals NA Illumina [232255] 8 leptin measurement http://www.ebi.ac.uk/efo/EFO_0005000 GCST90007307 Exome genotyping array [Illumina HumanExome BeadChip] 56802 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels 23,861 European ancestry, African American or Afro-Caribbean, East Asian ancestry, Hispanic or Latin American men NA Illumina [220735] 3 leptin measurement http://www.ebi.ac.uk/efo/EFO_0005000 GCST90007308 Exome genotyping array [Illumina HumanExome BeadChip] 23861 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels 32,940 European ancestry, African American or Afro-Caribbean, East Asian ancestry, Hispanic or Latin American women NA Illumina [227495] 6 leptin measurement http://www.ebi.ac.uk/efo/EFO_0005000 GCST90007309 Exome genotyping array [Illumina HumanExome BeadChip] 32940 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels 49,909 European ancestry individuals NA Illumina [204641] 7 leptin measurement http://www.ebi.ac.uk/efo/EFO_0005000 GCST90007310 Exome genotyping array [Illumina HumanExome BeadChip] 49909 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels 21,921 European ancestry men NA Illumina [185219] 2 leptin measurement http://www.ebi.ac.uk/efo/EFO_0005000 GCST90007311 Exome genotyping array [Illumina HumanExome BeadChip] 21921 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels 27,987 European ancestry women NA Illumina [193201] 5 leptin measurement http://www.ebi.ac.uk/efo/EFO_0005000 GCST90007312 Exome genotyping array [Illumina HumanExome BeadChip] 27987 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels 56,802 European ancestry, African American or Afro-Caribbean, East Asian ancestry, Hispanic or Latin American individuals NA Illumina [92082] 5 leptin measurement http://www.ebi.ac.uk/efo/EFO_0005000 GCST90007313 Exome genotyping array [Illumina HumanExome BeadChip] 56802 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels 23,861 European ancestry, African American or Afro-Caribbean, East Asian ancestry, Hispanic or Latin American men NA Illumina [60771] 2 leptin measurement http://www.ebi.ac.uk/efo/EFO_0005000 GCST90007314 Exome genotyping array [Illumina HumanExome BeadChip] 23861 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels 32,940 European ancestry, African American or Afro-Caribbean, East Asian ancestry, Hispanic or Latin American women NA Illumina [86076] 3 leptin measurement http://www.ebi.ac.uk/efo/EFO_0005000 GCST90007315 Exome genotyping array [Illumina HumanExome BeadChip] 32940 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels 49,909 European ancestry individuals NA Illumina [54083] 4 leptin measurement http://www.ebi.ac.uk/efo/EFO_0005000 GCST90007316 Exome genotyping array [Illumina HumanExome BeadChip] 49909 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels 21,921 European ancestry men NA Illumina [46904] 1 leptin measurement http://www.ebi.ac.uk/efo/EFO_0005000 GCST90007317 Exome genotyping array [Illumina HumanExome BeadChip] 21921 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels 27,987 European ancestry women NA Illumina [49551] 2 leptin measurement http://www.ebi.ac.uk/efo/EFO_0005000 GCST90007318 Exome genotyping array [Illumina HumanExome BeadChip] 27987 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels adjusted for BMI 56,708 European ancestry, African American or Afro-Caribbean, East Asian ancestry, Hispanic or Latin American individuals NA Illumina [232237] 8 BMI-adjusted leptin measurement http://www.ebi.ac.uk/efo/EFO_0007793 GCST90007319 Exome genotyping array [Illumina HumanExome BeadChip] 56708 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels adjusted for BMI 23,822 European ancestry, African American or Afro-Caribbean, East Asian ancestry, Hispanic or Latin American men NA Illumina [220721] 7 BMI-adjusted leptin measurement http://www.ebi.ac.uk/efo/EFO_0007793 GCST90007320 Exome genotyping array [Illumina HumanExome BeadChip] 23822 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels adjusted for BMI 32,886 European ancestry, African American or Afro-Caribbean, East Asian ancestry, Hispanic or Latin American women NA Illumina [227473] 8 BMI-adjusted leptin measurement http://www.ebi.ac.uk/efo/EFO_0007793 GCST90007321 Exome genotyping array [Illumina HumanExome BeadChip] 32886 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels adjusted for BMI 49,830 European ancestry individuals NA Illumina [204609] 7 BMI-adjusted leptin measurement http://www.ebi.ac.uk/efo/EFO_0007793 GCST90007322 Exome genotyping array [Illumina HumanExome BeadChip] 49830 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels adjusted for BMI 21,883 European ancestry men NA Illumina [185190] 5 BMI-adjusted leptin measurement http://www.ebi.ac.uk/efo/EFO_0007793 GCST90007323 Exome genotyping array [Illumina HumanExome BeadChip] 21883 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels adjusted for BMI 27,947 European ancestry women NA Illumina [193169] 7 BMI-adjusted leptin measurement http://www.ebi.ac.uk/efo/EFO_0007793 GCST90007324 Exome genotyping array [Illumina HumanExome BeadChip] 27947 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels adjusted for BMI 56,708 European ancestry, African American or Afro-Caribbean, East Asian ancestry, Hispanic or Latin American individuals NA Illumina [92057] 6 BMI-adjusted leptin measurement http://www.ebi.ac.uk/efo/EFO_0007793 GCST90007325 Exome genotyping array [Illumina HumanExome BeadChip] 56708 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels adjusted for BMI 23,822 European ancestry, African American or Afro-Caribbean, East Asian ancestry, Hispanic or Latin American men NA Illumina [60745] 2 BMI-adjusted leptin measurement http://www.ebi.ac.uk/efo/EFO_0007793 GCST90007326 Exome genotyping array [Illumina HumanExome BeadChip] 23822 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels adjusted for BMI 32,886 European ancestry, African American or Afro-Caribbean, East Asian ancestry, Hispanic or Latin American women NA Illumina [86054] 6 BMI-adjusted leptin measurement http://www.ebi.ac.uk/efo/EFO_0007793 GCST90007327 Exome genotyping array [Illumina HumanExome BeadChip] 32886 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels adjusted for BMI 49,830 European ancestry individuals NA Illumina [54056] 5 BMI-adjusted leptin measurement http://www.ebi.ac.uk/efo/EFO_0007793 GCST90007328 Exome genotyping array [Illumina HumanExome BeadChip] 49830 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels adjusted for BMI 21,883 European ancestry men NA Illumina [46877] 2 BMI-adjusted leptin measurement http://www.ebi.ac.uk/efo/EFO_0007793 GCST90007329 Exome genotyping array [Illumina HumanExome BeadChip] 21883 2020-10-02 32917775 Yaghootkar H 2020-09-11 Diabetes www.ncbi.nlm.nih.gov/pubmed/32917775 Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. circulating leptin levels adjusted for BMI 27,947 European ancestry women NA Illumina [49530] 6 BMI-adjusted leptin measurement http://www.ebi.ac.uk/efo/EFO_0007793 GCST90007330 Exome genotyping array [Illumina HumanExome BeadChip] 27947 2021-04-30 32928877 Jung SY 2020-09-14 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/32928877 Genome-wide association analysis of pro-inflammatory cytokines and gene-lifestyle interaction for invasive breast cancer risk: the WHI dbGaP Study. Serum C-reactive protein concentration 10,798 European ancestry women NA Affymetrix, Illumina [21784812] (imputed) 3 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST011583 Genome-wide genotyping array 10798 2021-04-30 32928877 Jung SY 2020-09-14 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/32928877 Genome-wide association analysis of pro-inflammatory cytokines and gene-lifestyle interaction for invasive breast cancer risk: the WHI dbGaP Study. Serum C-reactive protein concentration in non-obese individuals 7,179 European ancestry women NA Affymetrix, Illumina [21784812] (imputed) 1 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST011582 Genome-wide genotyping array 7179 2021-04-30 32928877 Jung SY 2020-09-14 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/32928877 Genome-wide association analysis of pro-inflammatory cytokines and gene-lifestyle interaction for invasive breast cancer risk: the WHI dbGaP Study. Serum C-reactive protein concentration in obesity 3,000 European ancestry women NA Affymetrix, Illumina [21784812] (imputed) 2 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST011581 Genome-wide genotyping array 3000 2021-04-30 32928877 Jung SY 2020-09-14 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/32928877 Genome-wide association analysis of pro-inflammatory cytokines and gene-lifestyle interaction for invasive breast cancer risk: the WHI dbGaP Study. Serum C-reactive protein concentration in inactive individuals 5,958 European ancestry women NA Affymetrix, Illumina [21784812] (imputed) 1 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST011580 Genome-wide genotyping array 5958 2021-04-30 32928877 Jung SY 2020-09-14 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/32928877 Genome-wide association analysis of pro-inflammatory cytokines and gene-lifestyle interaction for invasive breast cancer risk: the WHI dbGaP Study. Serum C-reactive protein concentration in low fat diet 2,306 European ancestry women NA Affymetrix, Illumina [21784812] (imputed) 1 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST011579 Genome-wide genotyping array 2306 2021-04-30 32928877 Jung SY 2020-09-14 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/32928877 Genome-wide association analysis of pro-inflammatory cytokines and gene-lifestyle interaction for invasive breast cancer risk: the WHI dbGaP Study. Serum C-reactive protein concentration in high fat diet 7,873 European ancestry women NA Affymetrix, Illumina [21784812] (imputed) 2 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST011578 Genome-wide genotyping array 7873 2021-04-30 32928877 Jung SY 2020-09-14 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/32928877 Genome-wide association analysis of pro-inflammatory cytokines and gene-lifestyle interaction for invasive breast cancer risk: the WHI dbGaP Study. Serum C-reactive protein concentration in visceral obesity (waist-hip ratio) 2,928 European ancestry women NA Affymetrix, Illumina [21784812] (imputed) 1 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST011577 Genome-wide genotyping array 2928 2021-04-30 32928877 Jung SY 2020-09-14 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/32928877 Genome-wide association analysis of pro-inflammatory cytokines and gene-lifestyle interaction for invasive breast cancer risk: the WHI dbGaP Study. Serum C-reactive protein concentration in visceral obesity (waist circumference) 4,155 European ancestry women NA Affymetrix, Illumina [21784812] (imputed) 2 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST011576 Genome-wide genotyping array 4155 2021-04-30 32928877 Jung SY 2020-09-14 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/32928877 Genome-wide association analysis of pro-inflammatory cytokines and gene-lifestyle interaction for invasive breast cancer risk: the WHI dbGaP Study. Serum interleukin-6 concentration 10,798 European ancestry women NA Affymetrix, Illumina [21784812] (imputed) 1 interleukin-6 measurement http://www.ebi.ac.uk/efo/EFO_0004810 GCST011575 Genome-wide genotyping array 10798 2021-04-30 32928877 Jung SY 2020-09-14 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/32928877 Genome-wide association analysis of pro-inflammatory cytokines and gene-lifestyle interaction for invasive breast cancer risk: the WHI dbGaP Study. Serum interleukin-6 concentration in non-visceral-obese individuals 7,251 European ancestry women NA Affymetrix, Illumina [21784812] (imputed) 1 interleukin-6 measurement http://www.ebi.ac.uk/efo/EFO_0004810 GCST011574 Genome-wide genotyping array 7251 2021-04-30 32928877 Jung SY 2020-09-14 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/32928877 Genome-wide association analysis of pro-inflammatory cytokines and gene-lifestyle interaction for invasive breast cancer risk: the WHI dbGaP Study. Serum interleukin-6 concentration in high fat diet 7,873 European ancestry women NA Affymetrix, Illumina [21784812] (imputed) 1 interleukin-6 measurement http://www.ebi.ac.uk/efo/EFO_0004810 GCST011573 Genome-wide genotyping array 7873 2021-04-30 32928877 Jung SY 2020-09-14 Cancer Prev Res (Phila) www.ncbi.nlm.nih.gov/pubmed/32928877 Genome-wide association analysis of pro-inflammatory cytokines and gene-lifestyle interaction for invasive breast cancer risk: the WHI dbGaP Study. Serum interleukin-6 concentration in active individuals 4,221 European ancestry women NA Affymetrix, Illumina [21784812] (imputed) 1 interleukin-6 measurement http://www.ebi.ac.uk/efo/EFO_0004810 GCST011572 Genome-wide genotyping array 4221 2021-04-28 32944759 Deshmukh HA 2020-09-18 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/32944759 Genome-Wide Association Analysis of Pancreatic Beta Cell Glucose Sensitivity. Pancreatic beta-cell glucose sensitivity 3,017 European ancestry individuals 2,689 European ancestry individuals Illumina [8978282] (imputed) 9 diabetes mellitus biomarker http://www.ebi.ac.uk/efo/EFO_0006842 GCST011569 Genome-wide genotyping array 3017 2020-12-10 32938779 Kim HR 2020-09-16 Neurology www.ncbi.nlm.nih.gov/pubmed/32938779 Genetic variants beyond amyloid and tau associated with cognitive decline: A cohort study. Cognitive decline 185 MCI cases, 135 AD cases, 94 controls 39 MCI cases, 11 AC cases, 22 controls Illumina [6221501] (imputed) 0 cognitive decline measurement http://www.ebi.ac.uk/efo/EFO_0007710 GCST010865 Genome-wide genotyping array 414 2020-07-24 32439900 Ntalla I 2020-05-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32439900 Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction. PR interval 271,570 European ancestry individuals NA Affymetrix, Illumina [at least 167995] (imputed) 150 PR interval http://www.ebi.ac.uk/efo/EFO_0004462 GCST010320 Genome-wide genotyping array 271570 2020-07-24 32439900 Ntalla I 2020-05-21 Nat Commun www.ncbi.nlm.nih.gov/pubmed/32439900 Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction. PR interval 271,570 European ancestry individuals, 8,173 African American individuals, 12,823 Hispanic/Latino individuals NA Affymetrix, Illumina [at least 167995] (imputed) 215 PR interval http://www.ebi.ac.uk/efo/EFO_0004462 GCST010321 Genome-wide genotyping array 292566 2020-10-16 32986714 Fiorica PN 2020-09-28 PLoS One www.ncbi.nlm.nih.gov/pubmed/32986714 Multi-ethnic transcriptome-wide association study of prostate cancer. Prostate cancer 2,463 African American or Afro-Caribbean cases, 2,306 African American or Afro-Caribbean controls NA Illumina [15394464] (imputed) 2 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST90002423 Genome-wide genotyping array 4769 2020-10-16 32986714 Fiorica PN 2020-09-28 PLoS One www.ncbi.nlm.nih.gov/pubmed/32986714 Multi-ethnic transcriptome-wide association study of prostate cancer. Prostate cancer 1,106 Japanese American cases, 1,093 Japanese American controls NA Illumina [4623264] (imputed) 4 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST90002424 Genome-wide genotyping array 2199 2020-10-16 32986714 Fiorica PN 2020-09-28 PLoS One www.ncbi.nlm.nih.gov/pubmed/32986714 Multi-ethnic transcriptome-wide association study of prostate cancer. Prostate cancer 1,081 Hispanic or Latin American cases, 1,066 Hispanic or Latin American controls NA Illumina [7010834] (imputed) 1 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST90002425 Genome-wide genotyping array 2147 2021-07-02 32998551 Docherty AR 2020-10-01 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/32998551 Genome-Wide Association Study of Suicide Death and Polygenic Prediction of Clinical Antecedents. Suicide 3,413 European ancestry cases, 14,810 European ancestry controls NA Illumina [7519308] (imputed) 10 suicide http://www.ebi.ac.uk/efo/EFO_0007624 GCST011994 Genome-wide genotyping array 18223 2021-06-16 33011741 Steggink LC 2020-10-03 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/33011741 Genome-wide association study of cardiovascular disease in testicular cancer patients treated with platinum-based chemotherapy. cardiovascular disease in testicular cancer treated with platinum-based chemotherapy 53 cases, 322 controls NA Illumina [237087] 0 cardiovascular disease http://www.ebi.ac.uk/efo/EFO_0000319 GCST011907 Genome-wide genotyping array 375 2021-07-28 33004991 Sutoh Y 2020-10-01 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33004991 ALDH2 genotype modulates the association between alcohol consumption and AST/ALT ratio among middle-aged Japanese men: a genome-wide G × E interaction analysis. Aspartate aminotransferase levels x alcohol consumption interaction 7,856 Japanese ancestry individuals up to 4,388 Japanese ancestry individuals Illumina [7129678] (imputed) 0 aspartate aminotransferase measurement, alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0004736, http://www.ebi.ac.uk/efo/EFO_0007878 GCST012144 Genome-wide genotyping array 7856 2021-07-28 33004991 Sutoh Y 2020-10-01 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33004991 ALDH2 genotype modulates the association between alcohol consumption and AST/ALT ratio among middle-aged Japanese men: a genome-wide G × E interaction analysis. Gamma glutamyl transferase levels x alcohol consumption interaction 7,856 Japanese ancestry individuals up to 4,388 Japanese ancestry individuals Illumina [7129678] (imputed) 0 serum gamma-glutamyl transferase measurement, alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0004532, http://www.ebi.ac.uk/efo/EFO_0007878 GCST012143 Genome-wide genotyping array 7856 2021-07-28 33004991 Sutoh Y 2020-10-01 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33004991 ALDH2 genotype modulates the association between alcohol consumption and AST/ALT ratio among middle-aged Japanese men: a genome-wide G × E interaction analysis. Alanine aminotransferase levels x alcohol consumption interaction 7,856 Japanese ancestry individuals up to 4,388 Japanese ancestry individuals Illumina [7129678] (imputed) 0 serum alanine aminotransferase measurement, alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0004735, http://www.ebi.ac.uk/efo/EFO_0007878 GCST012142 Genome-wide genotyping array 7856 2021-07-28 33004991 Sutoh Y 2020-10-01 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33004991 ALDH2 genotype modulates the association between alcohol consumption and AST/ALT ratio among middle-aged Japanese men: a genome-wide G × E interaction analysis. Aspartate aminotransferase to alanine aminotransferase ratio x alcohol consumption interaction 7,856 Japanese ancestry individuals up to 4,388 Japanese ancestry individuals Illumina [7129678] (imputed) 1 alcohol consumption measurement, aspartate aminotransferase to alanine aminotransferase ratio http://www.ebi.ac.uk/efo/EFO_0007878, http://www.ebi.ac.uk/efo/EFO_0010934 GCST012141 Genome-wide genotyping array 7856 2021-07-07 33002292 Shinohara T 2020-10-01 J Cell Mol Med www.ncbi.nlm.nih.gov/pubmed/33002292 Inherited genetic variants associated with glucocorticoid sensitivity in leukaemia cells. glucocorticoid receptor gene expression in B-cell precursor acute lymphoblastic leukaemia 72 Japanese ancestry leukaemic cell lines NA Illumina [331281] 16 NA NA GCST011998 Genome-wide genotyping array 72 2021-07-07 33002292 Shinohara T 2020-10-01 J Cell Mol Med www.ncbi.nlm.nih.gov/pubmed/33002292 Inherited genetic variants associated with glucocorticoid sensitivity in leukaemia cells. prednisolone sensitivity in B-cell precursor acute lymphoblastic leukaemia 72 Japanese ancestry leukaemic cell lines NA Illumina [331281] 3 response to prednisolone http://www.ebi.ac.uk/efo/EFO_0009168 GCST011997 Genome-wide genotyping array 72 2021-07-07 33002292 Shinohara T 2020-10-01 J Cell Mol Med www.ncbi.nlm.nih.gov/pubmed/33002292 Inherited genetic variants associated with glucocorticoid sensitivity in leukaemia cells. dexamethasone sensitivity in B-cell precursor acute lymphoblastic leukaemia 72 Japanese ancestry leukaemic cell lines NA Illumina [331281] 3 response to dexamethasone http://www.ebi.ac.uk/efo/EFO_0010933 GCST011996 Genome-wide genotyping array 72 2021-07-08 33002439 Jin G 2020-10-01 Lancet Oncol www.ncbi.nlm.nih.gov/pubmed/33002439 Genetic risk, incident gastric cancer, and healthy lifestyle: a meta-analysis of genome-wide association studies and prospective cohort study. Gastric cancer 10,254 Han Chinese ancestry cases, 10,914 Han Chinese ancestry controls NA Affymetrix, Illumina [6957974] (imputed) 35 gastric carcinoma http://www.ebi.ac.uk/efo/EFO_0000178 GCST012016 Genome-wide genotyping array 21168 2020-08-27 32433515 Meyers JL 2020-05-20 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/32433515 A genome-wide association study of interhemispheric theta EEG coherence: implications for neural connectivity and alcohol use behavior. Theta EEG coherence 6,644 European ancestry individuals, 2,166 African American individuals NA Illumina [6832792] (imputed) 4 theta wave measurement http://www.ebi.ac.uk/efo/EFO_0006873 GCST010464 Genome-wide genotyping array 8810 2020-08-25 32421744 Gzara C 2020-05-18 PLoS Pathog www.ncbi.nlm.nih.gov/pubmed/32421744 Family-based genome-wide association study of leprosy in Vietnam. Leprosy 1,749 Vietnamese ancestry cases 1,181 Vietnamese ancestry cases, 688 Vietnamese ancestry controls Illumina [5607170] (imputed) 5 leprosy http://www.ebi.ac.uk/efo/EFO_0001054 GCST010457 Genome-wide genotyping array 1749 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Lymphocyte counts 524,923 European ancestry individuals NA Affymetrix, Illumina [50265552] (imputed) 465 lymphocyte count http://www.ebi.ac.uk/efo/EFO_0004587 GCST90002316 Genome-wide genotyping array 524923 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Lymphocyte counts 89,266 East Asian ancestry individuals NA Affymetrix, Illumina [16289068] (imputed) 16 lymphocyte count http://www.ebi.ac.uk/efo/EFO_0004587 GCST90002317 Genome-wide genotyping array 89266 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Lymphocyte counts 7,541 Hispanic or Latin American individuals NA Affymetrix, Illumina [25652707] (imputed) 0 lymphocyte count http://www.ebi.ac.uk/efo/EFO_0004587 GCST90002318 Genome-wide genotyping array 7541 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Lymphocyte counts 8,163 South Asian ancestry individuals NA Affymetrix, Illumina [28469925] (imputed) 1 lymphocyte count http://www.ebi.ac.uk/efo/EFO_0004587 GCST90002319 Genome-wide genotyping array 8163 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Lymphocyte counts 643,370 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals NA Affymetrix, Illumina [23472807] (imputed) 409 lymphocyte count http://www.ebi.ac.uk/efo/EFO_0004587 GCST90002320 Genome-wide genotyping array 643370 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean corpuscular hemoglobin 11,974 African American or Afro-Caribbean and African ancestry individuals NA Affymetrix, Illumina [36043646] (imputed) 7 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90002321 Genome-wide genotyping array 11974 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean corpuscular hemoglobin 486,823 European ancestry individuals NA Affymetrix, Illumina [50266654] (imputed) 423 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90002322 Genome-wide genotyping array 486823 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean corpuscular hemoglobin 119,629 East Asian ancestry individuals NA Affymetrix, Illumina [16286228] (imputed) 77 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90002323 Genome-wide genotyping array 119629 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean corpuscular hemoglobin 3,518 Hispanic or Latin American individuals NA Affymetrix, Illumina [24999652] (imputed) 1 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90002324 Genome-wide genotyping array 3518 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean corpuscular hemoglobin 8,181 South Asian ancestry individuals NA Affymetrix, Illumina [28486451] (imputed) 10 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90002325 Genome-wide genotyping array 8181 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean corpuscular hemoglobin 630,125 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals NA Affymetrix, Illumina [20825802] (imputed) 384 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90002326 Genome-wide genotyping array 630125 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean corpuscular hemoglobin concentration 12,766 African American or Afro-Caribbean and African ancestry individuals NA Affymetrix, Illumina [36221496] (imputed) 2 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90002327 Genome-wide genotyping array 12766 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean corpuscular hemoglobin concentration 491,553 European ancestry individuals NA Affymetrix, Illumina [50282193] (imputed) 191 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90002328 Genome-wide genotyping array 491553 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean corpuscular hemoglobin concentration 126,151 East Asian ancestry individuals NA Affymetrix, Illumina [16289083] (imputed) 36 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90002329 Genome-wide genotyping array 126151 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean corpuscular hemoglobin concentration 3,518 Hispanic or Latin American individuals NA Affymetrix, Illumina [24999636] (imputed) 1 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90002330 Genome-wide genotyping array 3518 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean corpuscular hemoglobin concentration 8,185 South Asian ancestry individuals NA Affymetrix, Illumina [28487724] (imputed) 2 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90002331 Genome-wide genotyping array 8185 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean corpuscular hemoglobin concentration 642,173 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals NA Affymetrix, Illumina [21126107] (imputed) 166 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90002332 Genome-wide genotyping array 642173 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean corpuscular volume 14,222 African American or Afro-Caribbean and African ancestry individuals NA Affymetrix, Illumina [36679766] (imputed) 2 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST90002333 Genome-wide genotyping array 14222 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean corpuscular volume 544,127 European ancestry individuals NA Affymetrix, Illumina [50615308] (imputed) 466 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST90002334 Genome-wide genotyping array 544127 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean corpuscular volume 121,047 East Asian ancestry individuals NA Affymetrix, Illumina [16286195] (imputed) 79 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST90002335 Genome-wide genotyping array 121047 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean corpuscular volume 9,298 Hispanic or Latin American individuals NA Affymetrix, Illumina [26810224] (imputed) 6 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST90002336 Genome-wide genotyping array 9298 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean corpuscular volume 8,188 South Asian ancestry individuals NA Affymetrix, Illumina [28492174] (imputed) 10 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST90002337 Genome-wide genotyping array 8188 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean corpuscular volume 696,882 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals NA Affymetrix, Illumina [24246363] (imputed) 454 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST90002338 Genome-wide genotyping array 696882 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Monocyte count 13,471 African American or Afro-Caribbean and African ancestry individuals NA Affymetrix, Illumina [36452625] (imputed) 10 monocyte count http://www.ebi.ac.uk/efo/EFO_0005091 GCST90002339 Genome-wide genotyping array 13471 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Monocyte count 521,594 European ancestry individuals NA Affymetrix, Illumina [50262088] (imputed) 455 monocyte count http://www.ebi.ac.uk/efo/EFO_0005091 GCST90002340 Genome-wide genotyping array 521594 2021-10-18 33980691 Martin S 2021-05-12 Diabetes www.ncbi.nlm.nih.gov/pubmed/33980691 Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease. Body fat percentage 442,278 European ancestry individuals NA NR [NR] (imputed) 254 body fat percentage http://www.ebi.ac.uk/efo/EFO_0007800 GCST90020232 Genome-wide genotyping array 442278 2021-10-18 33980691 Martin S 2021-05-12 Diabetes www.ncbi.nlm.nih.gov/pubmed/33980691 Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease. High density lipoprotein cholesterol levels 392,965 European ancestry individuals NA NR [NR] (imputed) 94 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST90020233 Genome-wide genotyping array 392965 2021-10-18 33980691 Martin S 2021-05-12 Diabetes www.ncbi.nlm.nih.gov/pubmed/33980691 Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease. Sex hormone-binding globulin levels 389,354 European ancestry individuals NA NR [NR] (imputed) 71 sex hormone-binding globulin measurement http://www.ebi.ac.uk/efo/EFO_0004696 GCST90020234 Genome-wide genotyping array 389354 2021-10-18 33980691 Martin S 2021-05-12 Diabetes www.ncbi.nlm.nih.gov/pubmed/33980691 Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease. Triglycerides 429,011 European ancestry individuals NA NR [NR] (imputed) 77 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST90020235 Genome-wide genotyping array 429011 2021-10-18 33980691 Martin S 2021-05-12 Diabetes www.ncbi.nlm.nih.gov/pubmed/33980691 Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease. Alanine aminotransferase levels 429,203 European ancestry individuals NA NR [NR] (imputed) 55 serum alanine aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004735 GCST90020236 Genome-wide genotyping array 429203 2021-10-18 33980691 Martin S 2021-05-12 Diabetes www.ncbi.nlm.nih.gov/pubmed/33980691 Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease. Aspartate aminotransferase levels 424,778 European ancestry individuals NA NR [NR] (imputed) 36 aspartate aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004736 GCST90020237 Genome-wide genotyping array 424778 2021-10-18 33980691 Martin S 2021-05-12 Diabetes www.ncbi.nlm.nih.gov/pubmed/33980691 Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease. Visceral adipose tissue 32,859 European ancestry individuals NA NR [NR] (imputed) 0 visceral adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004765 GCST90038587 Genome-wide genotyping array 32859 2021-10-18 33980691 Martin S 2021-05-12 Diabetes www.ncbi.nlm.nih.gov/pubmed/33980691 Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease. Subcutaneous adipose tissue 32,859 European ancestry individuals NA NR [NR] (imputed) 0 subcutaneous adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004766 GCST90038588 Genome-wide genotyping array 32859 2021-10-18 33980691 Martin S 2021-05-12 Diabetes www.ncbi.nlm.nih.gov/pubmed/33980691 Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease. Visceral adipose tissue/subcutaneous adipose tissue ratio 32,859 European ancestry individuals NA NR [NR] (imputed) 0 visceral:subcutaneous adipose tissue ratio http://www.ebi.ac.uk/efo/EFO_0004767 GCST90038589 Genome-wide genotyping array 32859 2021-10-18 33980691 Martin S 2021-05-12 Diabetes www.ncbi.nlm.nih.gov/pubmed/33980691 Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease. Pancreas fat 24,673 European ancestry individuals NA NR [NR] (imputed) 0 body fat percentage http://www.ebi.ac.uk/efo/EFO_0007800 GCST90038590 Genome-wide genotyping array 24673 2021-10-18 33980691 Martin S 2021-05-12 Diabetes www.ncbi.nlm.nih.gov/pubmed/33980691 Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease. Percent liver fat 32,655 European ancestry individuals NA NR [NR] (imputed) 0 liver fat measurement http://www.ebi.ac.uk/efo/EFO_0010821 GCST90038591 Genome-wide genotyping array 32655 2021-10-18 33980691 Martin S 2021-05-12 Diabetes www.ncbi.nlm.nih.gov/pubmed/33980691 Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease. Pancreas volume 31,758 European ancestry individuals NA NR [NR] (imputed) 0 body weights and measures http://www.ebi.ac.uk/efo/EFO_0004324 GCST90038592 Genome-wide genotyping array 31758 2021-10-18 33980691 Martin S 2021-05-12 Diabetes www.ncbi.nlm.nih.gov/pubmed/33980691 Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease. Liver volume 32,859 European ancestry individuals NA NR [NR] (imputed) 0 body weights and measures http://www.ebi.ac.uk/efo/EFO_0004324 GCST90038593 Genome-wide genotyping array 32859 2021-10-18 33980691 Martin S 2021-05-12 Diabetes www.ncbi.nlm.nih.gov/pubmed/33980691 Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease. Metabolic biomarkers (multivariate analysis) 389,354 European ancestry individuals NA NR [NR] (imputed) 254 aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement http://www.ebi.ac.uk/efo/EFO_0004736, http://www.ebi.ac.uk/efo/EFO_0004735, http://www.ebi.ac.uk/efo/EFO_0009946, http://www.ebi.ac.uk/efo/EFO_0007800, http://www.ebi.ac.uk/efo/EFO_0004612, http://www.ebi.ac.uk/efo/EFO_0004696 GCST90038594 Genome-wide genotyping array 389354 2021-10-18 34046847 Yao Y 2021-05-27 Endocrine www.ncbi.nlm.nih.gov/pubmed/34046847 Evaluate the effects of serum urate level on bone mineral density: a genome-wide gene-environment interaction analysis in UK Biobank cohort. Heel bone mineral density x serum urate levels interaction 110,465 men, 127,334 women NA Affymetrix [NR] (imputed) 161 heel bone mineral density, urate measurement http://www.ebi.ac.uk/efo/EFO_0009270, http://www.ebi.ac.uk/efo/EFO_0004531 GCST012489 Genome-wide genotyping array 237799 2021-10-18 34046847 Yao Y 2021-05-27 Endocrine www.ncbi.nlm.nih.gov/pubmed/34046847 Evaluate the effects of serum urate level on bone mineral density: a genome-wide gene-environment interaction analysis in UK Biobank cohort. L1-L4 bone mineral density x serum urate levels interaction 2,207 men, 2,354 women NA Affymetrix [NR] (imputed) 46 urate measurement, spine bone mineral density http://www.ebi.ac.uk/efo/EFO_0004531, http://www.ebi.ac.uk/efo/EFO_0007701 GCST012488 Genome-wide genotyping array 4561 2021-10-18 34046847 Yao Y 2021-05-27 Endocrine www.ncbi.nlm.nih.gov/pubmed/34046847 Evaluate the effects of serum urate level on bone mineral density: a genome-wide gene-environment interaction analysis in UK Biobank cohort. Femur bone mineral density x serum urate levels interaction 2,225 men, 2,350 women NA Affymetrix [NR] (imputed) 653 urate measurement, bone density http://www.ebi.ac.uk/efo/EFO_0004531, http://www.ebi.ac.uk/efo/EFO_0003923 GCST012490 Genome-wide genotyping array 4575 2021-08-20 33667223 Lesseur C 2021-03-05 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33667223 Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers. Aerodigestive squamous cell cancer (pleiotropy) 7,426 European ancestry lung squamous cell carcinoma cases, 5,452 European ancestry oral and oropharynx squamous cell carcinoma cases, 693 European ancestry laryngeal squamous cell carcinoma cases, 316 European ancestry esophageal squamous cell carcinoma cases, 61,961 European ancestry controls NA Illumina [8468885] (imputed) 175 upper aerodigestive tract neoplasm http://www.ebi.ac.uk/efo/EFO_0004284 GCST012213 Genome-wide genotyping array 75848 2021-07-27 34187551 McCartney DL 2021-06-29 Genome Biol www.ncbi.nlm.nih.gov/pubmed/34187551 Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. DNA methylation-estimated granulocyte proportions 34,470 European ancestry individuals NA Affymetrix, Illumina [7568298] (imputed) 2 granulocyte count http://www.ebi.ac.uk/efo/EFO_0007987 GCST90014287 Genome-wide genotyping array, Genome-wide sequencing, Exome genotyping array, Targeted genotyping array 34470 2021-07-27 34187551 McCartney DL 2021-06-29 Genome Biol www.ncbi.nlm.nih.gov/pubmed/34187551 Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. DNA methylation GrimAge acceleration 34,467 European ancestry individuals NA Affymetrix, Illumina [7568149] (imputed) 4 aging http://purl.obolibrary.org/obo/GO_0007568 GCST90014288 Genome-wide genotyping array, Targeted genotyping array, Exome genotyping array, Genome-wide sequencing 34467 2021-07-27 34187551 McCartney DL 2021-06-29 Genome Biol www.ncbi.nlm.nih.gov/pubmed/34187551 Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. DNA methylation Hannum age acceleration 34,449 European ancestry individuals NA Affymetrix, Illumina [7565493] (imputed) 9 aging http://purl.obolibrary.org/obo/GO_0007568 GCST90014289 Genome-wide genotyping array, Targeted genotyping array, Exome genotyping array, Genome-wide sequencing 34449 2021-07-27 34187551 McCartney DL 2021-06-29 Genome Biol www.ncbi.nlm.nih.gov/pubmed/34187551 Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. Intrinsic epigenetic age acceleration 34,461 European ancestry individuals NA Affymetrix, Illumina [7567980] (imputed) 24 aging http://purl.obolibrary.org/obo/GO_0007568 GCST90014290 Genome-wide genotyping array, Targeted genotyping array, Exome genotyping array, Genome-wide sequencing 34461 2021-07-27 34187551 McCartney DL 2021-06-29 Genome Biol www.ncbi.nlm.nih.gov/pubmed/34187551 Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. DNA methylation-estimated plasminogen activator inhibitor-1 levels 34,448 European ancestry individuals NA Affymetrix, Illumina [7567618] (imputed) 5 plasminogen activator inhibitor 1 measurement http://www.ebi.ac.uk/efo/EFO_0004792 GCST90014291 Genome-wide genotyping array, Targeted genotyping array, Exome genotyping array, Genome-wide sequencing 34448 2021-07-27 34187551 McCartney DL 2021-06-29 Genome Biol www.ncbi.nlm.nih.gov/pubmed/34187551 Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. DNA methylation PhenoAge acceleration 34,463 European ancestry individuals NA Affymetrix, Illumina [7568033] (imputed) 12 aging http://purl.obolibrary.org/obo/GO_0007568 GCST90014292 Genome-wide genotyping array, Targeted genotyping array, Exome genotyping array, Genome-wide sequencing 34463 2021-07-27 34187551 McCartney DL 2021-06-29 Genome Biol www.ncbi.nlm.nih.gov/pubmed/34187551 Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. DNA methylation-estimated granulocyte proportions 6,152 African American individuals NA Affymetrix, Illumina [12990599] (imputed) 27 granulocyte count http://www.ebi.ac.uk/efo/EFO_0007987 GCST90014293 Genome-wide genotyping array, Targeted genotyping array, Exome genotyping array 6152 2021-07-27 34187551 McCartney DL 2021-06-29 Genome Biol www.ncbi.nlm.nih.gov/pubmed/34187551 Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. DNA methylation GrimAge acceleration 6,148 African American individuals NA Affymetrix, Illumina [12989440] (imputed) 11 aging http://purl.obolibrary.org/obo/GO_0007568 GCST90014294 Genome-wide genotyping array, Targeted genotyping array, Exome genotyping array 6148 2021-07-27 34187551 McCartney DL 2021-06-29 Genome Biol www.ncbi.nlm.nih.gov/pubmed/34187551 Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. DNA methylation Hannum age acceleration 6,148 African American individuals NA Affymetrix, Illumina [12989706] (imputed) 11 aging http://purl.obolibrary.org/obo/GO_0007568 GCST90014295 Genome-wide genotyping array, Targeted genotyping array, Exome genotyping array 6148 2021-07-27 34187551 McCartney DL 2021-06-29 Genome Biol www.ncbi.nlm.nih.gov/pubmed/34187551 Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. Intrinsic epigenetic age acceleration 6,148 African American individuals NA Affymetrix, Illumina [12989965] (imputed) 9 aging http://purl.obolibrary.org/obo/GO_0007568 GCST90014296 Genome-wide genotyping array, Targeted genotyping array, Exome genotyping array 6148 2021-07-27 34187551 McCartney DL 2021-06-29 Genome Biol www.ncbi.nlm.nih.gov/pubmed/34187551 Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. DNA methylation-estimated plasminogen activator inhibitor-1 levels 6,149 African American individuals NA Affymetrix, Illumina [12990252] (imputed) 11 plasminogen activator inhibitor 1 measurement http://www.ebi.ac.uk/efo/EFO_0004792 GCST90014297 Genome-wide genotyping array, Targeted genotyping array, Exome genotyping array 6149 2021-07-27 34187551 McCartney DL 2021-06-29 Genome Biol www.ncbi.nlm.nih.gov/pubmed/34187551 Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. DNA methylation PhenoAge acceleration 6,148 African American individuals NA Affymetrix, Illumina [12989038] (imputed) 12 aging http://purl.obolibrary.org/obo/GO_0007568 GCST90014298 Genome-wide genotyping array, Targeted genotyping array, Exome genotyping array 6148 2021-07-27 34187551 McCartney DL 2021-06-29 Genome Biol www.ncbi.nlm.nih.gov/pubmed/34187551 Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. DNA methylation-estimated granulocyte proportions 34,470 European ancestry individuals, 6,152 African American individuals NA Affymetrix, Illumina [6210527] (imputed) 8 granulocyte count http://www.ebi.ac.uk/efo/EFO_0007987 GCST90014299 Genome-wide genotyping array, Targeted genotyping array, Exome genotyping array, Genome-wide sequencing 40622 2021-07-27 34187551 McCartney DL 2021-06-29 Genome Biol www.ncbi.nlm.nih.gov/pubmed/34187551 Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. DNA methylation GrimAge acceleration 34,467 European ancestry individuals, 6,148 African American individuals NA Affymetrix, Illumina [6210740] (imputed) 6 aging http://purl.obolibrary.org/obo/GO_0007568 GCST90014300 Genome-wide genotyping array, Targeted genotyping array, Exome genotyping array, Genome-wide sequencing 40615 2021-07-27 34187551 McCartney DL 2021-06-29 Genome Biol www.ncbi.nlm.nih.gov/pubmed/34187551 Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. DNA methylation Hannum age acceleration 34,449 European ancestry individuals, 6,148 African American individuals NA Affymetrix, Illumina [6210504] (imputed) 10 aging http://purl.obolibrary.org/obo/GO_0007568 GCST90014301 Genome-wide genotyping array, Targeted genotyping array, Exome genotyping array, Genome-wide sequencing 40597 2021-07-27 34187551 McCartney DL 2021-06-29 Genome Biol www.ncbi.nlm.nih.gov/pubmed/34187551 Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. Intrinsic epigenetic age acceleration 34,461 European ancestry individuals, 6,148 African American individuals NA Affymetrix, Illumina [6211246] (imputed) 22 aging http://purl.obolibrary.org/obo/GO_0007568 GCST90014302 Genome-wide genotyping array, Targeted genotyping array, Exome genotyping array, Genome-wide sequencing 40609 2021-07-27 34187551 McCartney DL 2021-06-29 Genome Biol www.ncbi.nlm.nih.gov/pubmed/34187551 Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. DNA methylation-estimated plasminogen activator inhibitor-1 levels 34,448 European ancestry individuals, 6,149 African American individuals NA Affymetrix, Illumina [6211016] (imputed) 10 plasminogen activator inhibitor 1 measurement http://www.ebi.ac.uk/efo/EFO_0004792 GCST90014303 Genome-wide genotyping array, Targeted genotyping array, Exome genotyping array, Genome-wide sequencing 40597 2021-07-27 34187551 McCartney DL 2021-06-29 Genome Biol www.ncbi.nlm.nih.gov/pubmed/34187551 Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. DNA methylation PhenoAge acceleration 34,463 European ancestry individuals, 6,148 African American individuals NA Affymetrix, Illumina [6210360] (imputed) 10 aging http://purl.obolibrary.org/obo/GO_0007568 GCST90014304 Genome-wide genotyping array, Targeted genotyping array, Exome genotyping array, Genome-wide sequencing 40611 2009-10-30 19820697 Soranzo N 2009-10-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19820697 A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Mean platelet volume 4,627 European ancestry individuals 9,316 European ancestry individuals Affymetrix, Illumina [~ 2110000] (imputed) 15 mean platelet volume http://www.ebi.ac.uk/efo/EFO_0004584 GCST000497 Genome-wide genotyping array 4627 2009-10-30 19820697 Soranzo N 2009-10-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19820697 A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Hematological parameters 4,627 European ancestry individuals 9,316 European ancestry individuals Affymetrix, Illumina [~ 2110000] (imputed) 12 leukocyte count, erythrocyte count, mean corpuscular volume, mean corpuscular hemoglobin, platelet count http://www.ebi.ac.uk/efo/EFO_0004308, http://www.ebi.ac.uk/efo/EFO_0004305, http://www.ebi.ac.uk/efo/EFO_0004526, http://www.ebi.ac.uk/efo/EFO_0004527, http://www.ebi.ac.uk/efo/EFO_0004309 GCST000498 Genome-wide genotyping array 4627 2018-07-05 29875488 Sun BB 2018-06-06 Nature www.ncbi.nlm.nih.gov/pubmed/29875488 Genomic atlas of the human plasma proteome. Blood protein levels 3,301 European ancestry individuals NA Affymetrix [10572788] (imputed) 2784 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST005806 Genome-wide genotyping array 3301 2018-04-25 22922229 Cooper JD 2012-12-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22922229 Seven newly identified loci for autoimmune thyroid disease. Graves' disease 2,285 European ancestry cases, 9,364 European ancestry controls NA Illumina [103875] 12 Graves disease http://www.ebi.ac.uk/efo/EFO_0004237 GCST005526 Targeted genotyping array [ImmunoChip] 11649 2018-04-25 22922229 Cooper JD 2012-12-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22922229 Seven newly identified loci for autoimmune thyroid disease. Hashimoto thyroiditis 462 European ancestry cases, 9,364 European ancestry controls NA Illumina [103875] 1 Hashimoto's thyroiditis http://www.ebi.ac.uk/efo/EFO_0003779 GCST005525 Targeted genotyping array [ImmunoChip] 9826 2018-04-25 22922229 Cooper JD 2012-12-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22922229 Seven newly identified loci for autoimmune thyroid disease. Autoimmune thyroid diseases (Graves disease or Hashimoto's thyroiditis) 2,282 European ancestry Graves disease cases, 451 European ancestry Hashimoto's thyroiditis cases, 9364 European ancestry controls NA Illumina [103875] 11 autoimmune thyroid disease, Hashimoto's thyroiditis, Graves disease http://www.ebi.ac.uk/efo/EFO_0006812, http://www.ebi.ac.uk/efo/EFO_0003779, http://www.ebi.ac.uk/efo/EFO_0004237 GCST005524 Targeted genotyping array [ImmunoChip] 12097 2021-06-14 32409696 Hong M 2020-05-15 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/32409696 Potential causal association of a prolonged PR interval and clinical recurrence of atrial fibrillation after catheter ablation: a Mendelian randomization analysis. PR interval in atrial fibrillation treated with catheter ablation 586 cases, 1,136 controls NA NR [403402] 0 cardiac ablation, PR interval http://www.ebi.ac.uk/efo/EFO_0600009, http://www.ebi.ac.uk/efo/EFO_0004462 GCST011856 Genome-wide genotyping array 1722 2020-04-17 31669095 Zhu Z 2019-10-24 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/31669095 Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank. Asthma (childhood onset) 13,435 European ancestry cases, 393,186 European ancestry controls NA Affymetrix [~ 8270000] (imputed) 219 childhood onset asthma http://www.ebi.ac.uk/efo/EFO_0004591 GCST009841 Genome-wide genotyping array 406621 2020-04-17 31669095 Zhu Z 2019-10-24 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/31669095 Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank. Nonatopic asthma 28,862 European ancestry cases, 422,048 European ancestry controls NA Affymetrix [~ 8270000] (imputed) 109 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST009845 Genome-wide genotyping array 450910 2020-04-17 31669095 Zhu Z 2019-10-24 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/31669095 Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank. Atopic asthma 23,982 European ancestry cases, 393,169 European ancestry controls NA Affymetrix [~ 8270000] (imputed) 198 atopic asthma http://www.ebi.ac.uk/efo/EFO_0010638 GCST009850 Genome-wide genotyping array 417151 2020-04-17 31669095 Zhu Z 2019-10-24 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/31669095 Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank. Waist-to-hip ratio adjusted for BMI 457,690 European ancestry individuals NA Affymetrix [~ 8270000] (imputed) 1077 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST009858 Genome-wide genotyping array 457690 2020-04-17 31669095 Zhu Z 2019-10-24 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/31669095 Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank. Waist circumference adjusted for body mass index 457,690 European ancestry individuals NA Affymetrix [~ 8270000] (imputed) 1260 BMI-adjusted waist circumference http://www.ebi.ac.uk/efo/EFO_0007789 GCST009867 Genome-wide genotyping array 457690 2020-04-17 31669095 Zhu Z 2019-10-24 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/31669095 Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank. Body mass index 457,822 European ancestry individuals NA Affymetrix [~ 8270000] (imputed) 1644 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST009871 Genome-wide genotyping array 457822 2020-04-17 31669095 Zhu Z 2019-10-24 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/31669095 Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank. Adult onset asthma and/or BMI 33,418 European ancestry cases, 393,186 European ancestry controls, 31,218 European ancestry individuals NA Affymetrix [~ 8270000] (imputed) 8 adult onset asthma, body mass index http://www.ebi.ac.uk/efo/EFO_1002011, http://www.ebi.ac.uk/efo/EFO_0004340 GCST009868 Genome-wide genotyping array 457822 2020-04-17 31669095 Zhu Z 2019-10-24 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/31669095 Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank. Nonatopic asthma and/or BMI 28,862 European ancestry cases, 422,048 European ancestry controls, 6,912 European ancestry individuals NA Affymetrix [~ 8270000] (imputed) 10 body mass index, asthma http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0000270 GCST009866 Genome-wide genotyping array 457822 2020-04-17 31669095 Zhu Z 2019-10-24 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/31669095 Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank. Adult onset asthma and/or waist-to-hip ratio adjusted for BMI 33,418 European ancestry cases, 393,186 European ancestry controls, 31,086 European ancestry individuals NA Affymetrix [~ 8270000] (imputed) 6 BMI-adjusted waist-hip ratio, adult onset asthma http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_1002011 GCST009865 Genome-wide genotyping array 457690 2020-04-17 31669095 Zhu Z 2019-10-24 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/31669095 Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank. Nonatopic asthma and/or waist-to-hip ratio adjusted for BMI 28,862 European ancestry cases, 422,048 European ancestry controls, 6,780 European ancestry individuals NA Affymetrix [~ 8270000] (imputed) 8 BMI-adjusted waist-hip ratio, asthma http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0000270 GCST009862 Genome-wide genotyping array 457690 2020-04-17 31669095 Zhu Z 2019-10-24 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/31669095 Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank. Adult onset asthma or type 2 diabetes 33,418 European ancestry asthma cases, 393,186 European ancestry asthma controls, 159,208 European ancestry diabetes cases and controls NA Affymetrix [up to 8270000] (imputed) 6 adult onset asthma, type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_1002011, http://www.ebi.ac.uk/efo/EFO_0001360 GCST009859 Genome-wide genotyping array 585812 2020-04-17 31669095 Zhu Z 2019-10-24 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/31669095 Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank. Nonatopic asthma or type 2 diabetes 28,862 European ancestry asthma cases, 422,048 European ancestry asthma controls, 159,208 European ancestry diabetes cases and controls NA Affymetrix [up to 8270000] (imputed) 5 type II diabetes mellitus, asthma http://www.ebi.ac.uk/efo/EFO_0001360, http://www.ebi.ac.uk/efo/EFO_0000270 GCST009857 Genome-wide genotyping array 610118 2020-04-17 31669095 Zhu Z 2019-10-24 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/31669095 Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank. Adult onset asthma or fasting insulin levels 33,418 European ancestry cases, 393,186 European ancestry controls, 51,750 European ancestry individuals NA Affymetrix [~ 7660000] (imputed) 0 adult onset asthma, fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_1002011, http://www.ebi.ac.uk/efo/EFO_0004466 GCST009855 Genome-wide genotyping array 478354 2020-04-17 31669095 Zhu Z 2019-10-24 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/31669095 Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank. Nonatopic asthma or fasting insulin levels 28,862 European ancestry cases, 422,048 European ancestry controls, 51,750 European ancestry individuals NA Affymetrix [~ 7660000] (imputed) 0 asthma, fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0000270, http://www.ebi.ac.uk/efo/EFO_0004466 GCST009851 Genome-wide genotyping array 502660 2020-04-17 31669095 Zhu Z 2019-10-24 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/31669095 Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank. Adult onset asthma or fasting glucose levels 33,418 European ancestry cases, 393,186 European ancestry controls, 58,047 European ancestry individuals NA Affymetrix [~ 7660000] (imputed) 1 adult onset asthma, fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_1002011, http://www.ebi.ac.uk/efo/EFO_0004465 GCST009848 Genome-wide genotyping array 484651 2020-04-17 31669095 Zhu Z 2019-10-24 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/31669095 Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank. Nonatopic asthma or fasting glucose levels 28,862 European ancestry cases, 422,048 European ancestry controls, 58,047 European ancestry individuals NA Affymetrix [~ 7660000] (imputed) 1 fasting blood glucose measurement, asthma http://www.ebi.ac.uk/efo/EFO_0004465, http://www.ebi.ac.uk/efo/EFO_0000270 GCST009843 Genome-wide genotyping array 508957 2020-04-17 31669095 Zhu Z 2019-10-24 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/31669095 Shared Genetic and Experimental Links between Obesity-Related Traits and Asthma Subtypes in UK Biobank. Asthma (adult onset) 33,418 European ancestry cases, 393,186 European ancestry controls NA Affymetrix [~ 8270000] (imputed) 86 adult onset asthma http://www.ebi.ac.uk/efo/EFO_1002011 GCST009842 Genome-wide genotyping array 426604 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Red blood cell count 8,189 South Asian ancestry individuals NA Affymetrix, Illumina [28493162] (imputed) 5 red blood cell density measurement http://www.ebi.ac.uk/efo/EFO_0007978 GCST90002366 Genome-wide genotyping array 8189 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Red blood cell count 727,624 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals NA Affymetrix, Illumina [24332387] (imputed) 449 red blood cell density measurement http://www.ebi.ac.uk/efo/EFO_0007978 GCST90002367 Genome-wide genotyping array 727624 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Red cell distribution width 13,519 African American or Afro-Caribbean and African ancestry individuals NA Affymetrix, Illumina [36660117] (imputed) 5 red blood cell distribution width http://www.ebi.ac.uk/efo/EFO_0005192 GCST90002368 Genome-wide genotyping array 13519 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Red cell distribution width 531,774 European ancestry individuals NA Affymetrix, Illumina [49860007] (imputed) 385 red blood cell distribution width http://www.ebi.ac.uk/efo/EFO_0005192 GCST90002369 Genome-wide genotyping array 531774 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Red cell distribution width 8,526 Hispanic or Latin American individuals NA Affymetrix, Illumina [26792043] (imputed) 2 red blood cell distribution width http://www.ebi.ac.uk/efo/EFO_0005192 GCST90002370 Genome-wide genotyping array 8526 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Red cell distribution width 8,166 South Asian ancestry individuals NA Affymetrix, Illumina [28471494] (imputed) 5 red blood cell distribution width http://www.ebi.ac.uk/efo/EFO_0005192 GCST90002371 Genome-wide genotyping array 8166 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Red cell distribution width 563,352 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals NA Affymetrix, Illumina [22063850] (imputed) 340 red blood cell distribution width http://www.ebi.ac.uk/efo/EFO_0005192 GCST90002372 Genome-wide genotyping array 563352 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. White blood cell count 15,061 African American or Afro-Caribbean and African ancestry individuals NA Affymetrix, Illumina [36864690] (imputed) 22 myeloid white cell count http://www.ebi.ac.uk/efo/EFO_0007988 GCST90002373 Genome-wide genotyping array 15061 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. White blood cell count 562,243 European ancestry individuals NA Affymetrix, Illumina [50601830] (imputed) 478 myeloid white cell count http://www.ebi.ac.uk/efo/EFO_0007988 GCST90002374 Genome-wide genotyping array 562243 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. White blood cell count 151,807 East Asian ancestry individuals NA Affymetrix, Illumina [16710636] (imputed) 38 myeloid white cell count http://www.ebi.ac.uk/efo/EFO_0007988 GCST90002375 Genome-wide genotyping array 151807 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. White blood cell count 9,368 Hispanic or Latin American individuals NA Affymetrix, Illumina [26925380] (imputed) 4 myeloid white cell count http://www.ebi.ac.uk/efo/EFO_0007988 GCST90002376 Genome-wide genotyping array 9368 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. White blood cell count 8,188 South Asian ancestry individuals NA Affymetrix, Illumina [28492541] (imputed) 1 myeloid white cell count http://www.ebi.ac.uk/efo/EFO_0007988 GCST90002377 Genome-wide genotyping array 8188 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. White blood cell count 746,667 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals NA Affymetrix, Illumina [24649327] (imputed) 443 myeloid white cell count http://www.ebi.ac.uk/efo/EFO_0007988 GCST90002378 Genome-wide genotyping array 746667 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Monocyte count 88,929 East Asian ancestry individuals NA Affymetrix, Illumina [16289044] (imputed) 34 monocyte count http://www.ebi.ac.uk/efo/EFO_0005091 GCST90002341 Genome-wide genotyping array 88929 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Monocyte count 7,543 Hispanic or Latin American individuals NA Affymetrix, Illumina [25652698] (imputed) 1 monocyte count http://www.ebi.ac.uk/efo/EFO_0005091 GCST90002342 Genome-wide genotyping array 7543 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Monocyte count 7,043 South Asian ancestry individuals NA Affymetrix, Illumina [28465834] (imputed) 3 monocyte count http://www.ebi.ac.uk/efo/EFO_0005091 GCST90002343 Genome-wide genotyping array 7043 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Monocyte count 639,696 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals NA Affymetrix, Illumina [23467995] (imputed) 394 monocyte count http://www.ebi.ac.uk/efo/EFO_0005091 GCST90002344 Genome-wide genotyping array 639696 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean platelet volume 10,737 African American or Afro-Caribbean and African ancestry individuals NA Affymetrix, Illumina [36042313] (imputed) 13 mean platelet volume http://www.ebi.ac.uk/efo/EFO_0004584 GCST90002345 Genome-wide genotyping array 10737 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean platelet volume 460,935 European ancestry individuals NA Affymetrix, Illumina [49660172] (imputed) 423 mean platelet volume http://www.ebi.ac.uk/efo/EFO_0004584 GCST90002346 Genome-wide genotyping array 460935 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean platelet volume 2,810 Hispanic or Latin American individuals NA Affymetrix, Illumina [24878602] (imputed) 3 mean platelet volume http://www.ebi.ac.uk/efo/EFO_0004584 GCST90002347 Genome-wide genotyping array 2810 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean platelet volume 8,189 South Asian ancestry individuals NA Affymetrix, Illumina [28493265] (imputed) 11 mean platelet volume http://www.ebi.ac.uk/efo/EFO_0004584 GCST90002348 Genome-wide genotyping array 8189 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Mean platelet volume 484,042 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals NA Affymetrix, Illumina [17210439] (imputed) 392 mean platelet volume http://www.ebi.ac.uk/efo/EFO_0004584 GCST90002349 Genome-wide genotyping array 484042 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Neutrophil count 13,476 African American or Afro-Caribbean and African ancestry individuals NA Affymetrix, Illumina [36456987] (imputed) 21 neutrophil count http://www.ebi.ac.uk/efo/EFO_0004833 GCST90002350 Genome-wide genotyping array 13476 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Neutrophil count 519,288 European ancestry individuals NA Affymetrix, Illumina [50250472] (imputed) 397 neutrophil count http://www.ebi.ac.uk/efo/EFO_0004833 GCST90002351 Genome-wide genotyping array 519288 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Neutrophil count 78,744 East Asian ancestry individuals NA Affymetrix, Illumina [16289093] (imputed) 17 neutrophil count http://www.ebi.ac.uk/efo/EFO_0004833 GCST90002352 Genome-wide genotyping array 78744 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Neutrophil count 7,542 Hispanic or Latin American individuals NA Affymetrix, Illumina [25652697] (imputed) 5 neutrophil count http://www.ebi.ac.uk/efo/EFO_0004833 GCST90002353 Genome-wide genotyping array 7542 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Neutrophil count 8,165 South Asian ancestry individuals NA Affymetrix, Illumina [28471362] (imputed) 1 neutrophil count http://www.ebi.ac.uk/efo/EFO_0004833 GCST90002354 Genome-wide genotyping array 8165 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Neutrophil count 627,215 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals NA Affymetrix, Illumina [23114412] (imputed) 352 neutrophil count http://www.ebi.ac.uk/efo/EFO_0004833 GCST90002355 Genome-wide genotyping array 627215 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Platelet count 15,171 African American or Afro-Caribbean and African ancestry individuals NA Affymetrix, Illumina [36877391] (imputed) 9 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST90002356 Genome-wide genotyping array 15171 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Platelet count 542,827 European ancestry individuals NA Affymetrix, Illumina [50241410] (imputed) 556 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST90002357 Genome-wide genotyping array 542827 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Platelet count 145,648 East Asian ancestry individuals NA Affymetrix, Illumina [16710488] (imputed) 81 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST90002358 Genome-wide genotyping array 145648 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Platelet count 9,367 Hispanic or Latin American individuals NA Affymetrix, Illumina [26925389] (imputed) 2 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST90002359 Genome-wide genotyping array 9367 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Platelet count 8,188 South Asian ancestry individuals NA Affymetrix, Illumina [28492373] (imputed) 4 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST90002360 Genome-wide genotyping array 8188 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Platelet count 721,201 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals NA Affymetrix, Illumina [24588908] (imputed) 552 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST90002361 Genome-wide genotyping array 721201 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Red blood cell count 14,222 African American or Afro-Caribbean and African ancestry individuals NA Affymetrix, Illumina [36679691] (imputed) 3 red blood cell density measurement http://www.ebi.ac.uk/efo/EFO_0007978 GCST90002362 Genome-wide genotyping array 14222 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Red blood cell count 545,203 European ancestry individuals NA Affymetrix, Illumina [50628390] (imputed) 497 red blood cell density measurement http://www.ebi.ac.uk/efo/EFO_0007978 GCST90002363 Genome-wide genotyping array 545203 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Red blood cell count 150,708 East Asian ancestry individuals NA Affymetrix, Illumina [16709798] (imputed) 59 red blood cell density measurement http://www.ebi.ac.uk/efo/EFO_0007978 GCST90002364 Genome-wide genotyping array 150708 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Red blood cell count 9,302 Hispanic or Latin American individuals NA Affymetrix, Illumina [26810348] (imputed) 3 red blood cell density measurement http://www.ebi.ac.uk/efo/EFO_0007978 GCST90002365 Genome-wide genotyping array 9302 2021-07-07 33119750 Vergara C 2020-10-29 J Infect Dis www.ncbi.nlm.nih.gov/pubmed/33119750 A multi-ancestry sex stratified genome-wide association study of spontaneous clearance of hepatitis C virus. Hepatitis C (spontaneous viral clearance) 239 African ancestry male cases, 1,184 African ancestry male controls, 206 African ancestry female cases, 572 African ancestry female controls, 489 European ancestry male cases, 703 European ancestry male controls, 212 European ancestry female cases, 332 European ancestry female controls, 91 Hispanic male cases, 197 Hispanic male controls, 82 Hispanic female cases, 116 Hispanic female controls NA Illumina [5730693] (imputed) 14 remission, hepatitis C virus infection http://www.ebi.ac.uk/efo/EFO_0009785, http://www.ebi.ac.uk/efo/EFO_0003047 GCST011999 Genome-wide genotyping array 4423 2021-10-07 34122051 Wang H 2021-05-28 Front Aging Neurosci www.ncbi.nlm.nih.gov/pubmed/34122051 Similar Genetic Architecture of Alzheimer's Disease and Differential APOE Effect Between Sexes. Alzheimer's disease 4,010 European ancestry cases, 4,672 European ancestry controls NA NR [38043082] (imputed) 8 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST90038451 Genome-wide genotyping array 8682 2021-10-07 34122051 Wang H 2021-05-28 Front Aging Neurosci www.ncbi.nlm.nih.gov/pubmed/34122051 Similar Genetic Architecture of Alzheimer's Disease and Differential APOE Effect Between Sexes. Alzheimer's disease 5,705 European ancestry cases, 7,067 European ancestry controls NA NR [38043082] (imputed) 19 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST90038452 Genome-wide genotyping array 12772 2021-07-07 34127860 Robertson CC 2021-06-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34127860 Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes. Type 1 diabetes 20,065 European ancestry cases, 33,065 European ancestry controls, 1,045 other-admixed ancestry cases, 1,103 other-admixed ancestry controls, 1,043 African ancestry cases, 3,206 African ancestry controls NA Illumina [715631] (imputed) 72 type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001359 GCST90013445 Targeted genotyping array [ImmunoChip] 59527 2021-07-07 34127860 Robertson CC 2021-06-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34127860 Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes. Type 1 diabetes 13,458 non-Finnish Europeans ancestry cases, 20,143 non-Finnish Europeans ancestry controls NA Illumina [715631] (imputed) 0 type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001359 GCST90013446 Targeted genotyping array [ImmunoChip] 33601 2021-06-02 33937362 Moller PL 2021-04-16 Front Cardiovasc Med www.ncbi.nlm.nih.gov/pubmed/33937362 Sortilin as a Biomarker for Cardiovascular Disease Revisited. Sortilin levels (ELISA) 1,173 European ancestry individuals NA Illumina [4658994] (imputed) 1 sortilin measurement http://www.ebi.ac.uk/efo/EFO_0600000 GCST90019034 Genome-wide genotyping array 1173 2021-06-02 33937362 Moller PL 2021-04-16 Front Cardiovasc Med www.ncbi.nlm.nih.gov/pubmed/33937362 Sortilin as a Biomarker for Cardiovascular Disease Revisited. Sortilin levels (OLINK) 1,173 European ancestry individuals NA Illumina [4658994] (imputed) 1 sortilin measurement http://www.ebi.ac.uk/efo/EFO_0600000 GCST90019035 Genome-wide genotyping array 1173 2021-06-02 33937362 Moller PL 2021-04-16 Front Cardiovasc Med www.ncbi.nlm.nih.gov/pubmed/33937362 Sortilin as a Biomarker for Cardiovascular Disease Revisited. Sortilin levels (ELISA) 1,173 European ancestry individuals NA Illumina [44377997] 0 sortilin measurement http://www.ebi.ac.uk/efo/EFO_0600000 GCST90019036 Genome-wide sequencing 1173 2021-06-02 33937362 Moller PL 2021-04-16 Front Cardiovasc Med www.ncbi.nlm.nih.gov/pubmed/33937362 Sortilin as a Biomarker for Cardiovascular Disease Revisited. Sortilin levels (OLINK) 1,173 European ancestry individuals NA Illumina [44377997] 0 sortilin measurement http://www.ebi.ac.uk/efo/EFO_0600000 GCST90019037 Genome-wide sequencing 1173 2021-10-22 34227697 Loesch DP 2021-07-06 Ann Neurol www.ncbi.nlm.nih.gov/pubmed/34227697 Characterizing the Genetic Architecture of Parkinson's Disease in Latinos. Parkinson's disease 807 Latino cases, 690 Latino controls 1,234 Latino cases, 439,522 Latino controls Illumina [1240909] (imputed) 1 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST90026456 Genome-wide genotyping array 1497 2021-09-27 33887147 Young WJ 2021-04-22 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/33887147 Genetically-Determined Serum Calcium Levels and Markers of Ventricular Repolarisation: A Mendelian Randomization Study in the UK Biobank. Calcium levels 305,349 European ancestry individuals NA Affymetrix [NR] (imputed) 215 calcium measurement http://www.ebi.ac.uk/efo/EFO_0004838 GCST012398 Genome-wide genotyping array 305349 2021-10-22 34151794 Kang S 2021-06-18 J Alzheimers Dis www.ncbi.nlm.nih.gov/pubmed/34151794 Potential Novel Genes for Late-Onset Alzheimer's Disease in East-Asian Descent Identified by APOE-Stratified Genome-Wide Association Study. Late-onset Alzheimer's disease 1,119 Korean ancestry cases, 1,172 Korean ancestry controls 980 Japanese ancestry cases, 976 Japanese ancestry controls NR [35685761] (imputed) 1 late-onset Alzheimers disease http://www.ebi.ac.uk/efo/EFO_1001870 GCST90026599 Genome-wide genotyping array 2291 2021-10-22 34151794 Kang S 2021-06-18 J Alzheimers Dis www.ncbi.nlm.nih.gov/pubmed/34151794 Potential Novel Genes for Late-Onset Alzheimer's Disease in East-Asian Descent Identified by APOE-Stratified Genome-Wide Association Study. Late-onset Alzheimer’s disease in APOEe4 carriers 498 Korean ancestry cases, 196 Korean ancestry controls 545 Japanese ancestry cases, 161 Japanese ancestry controls NR [NR] (imputed) 0 late-onset Alzheimers disease http://www.ebi.ac.uk/efo/EFO_1001870 GCST90026600 Genome-wide genotyping array 694 2021-10-22 34151794 Kang S 2021-06-18 J Alzheimers Dis www.ncbi.nlm.nih.gov/pubmed/34151794 Potential Novel Genes for Late-Onset Alzheimer's Disease in East-Asian Descent Identified by APOE-Stratified Genome-Wide Association Study. Late-onset Alzheimer’s disease in APOEe4 non-carriers 621 Korean ancestry cases, 976 Korean ancestry controls 435 Japanese ancestry cases, 815 Japanese ancestry controls NR [NR] (imputed) 2 late-onset Alzheimers disease http://www.ebi.ac.uk/efo/EFO_1001870 GCST90026601 Genome-wide genotyping array 1597 2021-11-12 34154395 Brikell I 2021-06-22 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/34154395 Genetic, Clinical, and Sociodemographic Factors Associated With Stimulant Treatment Outcomes in ADHD. Stimulant treatment initiation in ADHD 7,427 European ancestry cases, 1,706 European ancestry controls NA Illumina [6361597] (imputed) 0 NA NA GCST90020214 Genome-wide genotyping array 9133 2021-11-12 34154395 Brikell I 2021-06-22 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/34154395 Genetic, Clinical, and Sociodemographic Factors Associated With Stimulant Treatment Outcomes in ADHD. Stimulant treatment discontinuation in ADHD 3,370 European ancestry cases, 3,854 European ancestry controls NA Illumina [6361597] (imputed) 0 NA NA GCST90020215 Genome-wide genotyping array 7224 2021-11-12 34154395 Brikell I 2021-06-22 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/34154395 Genetic, Clinical, and Sociodemographic Factors Associated With Stimulant Treatment Outcomes in ADHD. Switch to non-stimulant treatment in ADHD 1,137 European ancestry cases, 3,854 European ancestry controls NA Illumina [6361597] (imputed) 18 NA NA GCST90020216 Genome-wide genotyping array 4991 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Schizophrenia x sex interaction 31,567 European ancestry cases, 37,494 European ancestry controls, 1,836 East Asian ancestry cases, 3,383 East Asian ancestry controls NA NR [NR] (imputed) 35 schizophrenia, sex interaction measurement http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0008343 GCST012311 Genome-wide genotyping array 74280 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Schizophrenia x sex interaction 31,567 European ancestry cases, 37,494 European ancestry controls NA NR [NR] (imputed) 29 schizophrenia, sex interaction measurement http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0008343 GCST012310 Genome-wide genotyping array 69061 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Schizophrenia 11,361 European ancestry female cases, 18,119 European ancestry female controls, 20,206 European ancestry male cases, 19,375 European ancestry male controls, 686 East Asian ancestry female cases, 1,907 East Asian ancestry female controls, 1,150 East Asian ancestry male cases, 1,476 East Asian ancestry male controls NA NR [NR] (imputed) 20 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST012309 Genome-wide genotyping array 74280 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Schizophrenia 11,361 European ancestry female cases, 18,119 European ancestry female controls, 20,206 European ancestry male cases, 19,375 European ancestry male controls NA NR [NR] (imputed) 15 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST012308 Genome-wide genotyping array 69061 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Bipolar disorder x sex interaction 19,924 European ancestry cases, 30,547 European ancestry controls NA NR [NR] (imputed) 13 sex interaction measurement, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0000289 GCST012307 Genome-wide genotyping array 50471 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Bipolar disorder 11,897 European ancestry female cases, 15,538 European ancestry female controls, 8,027 European ancestry male cases, 15,009 European ancestry male controls NA NR [NR] (imputed) 11 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST012306 Genome-wide genotyping array 50471 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Major depressive disorder x sex interaction 15,970 European ancestry cases, 24,984 European ancestry controls NA NR [NR] (imputed) 27 unipolar depression, sex interaction measurement http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0008343 GCST012305 Genome-wide genotyping array 40954 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Major depressive disorder 10,865 European ancestry female cases, 12,753 European ancestry female controls, 5,105 European ancestry male cases, 12,231 European ancestry male controls NA NR [NR] (imputed) 6 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST012304 Genome-wide genotyping array 40954 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Recurrent major depressive disorder x sex interaction 5,314 European ancestry cases, 10,149 European ancestry controls NA NR [NR] (imputed) 10 unipolar depression, sex interaction measurement http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0008343 GCST012303 Genome-wide genotyping array 15463 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Recurrent major depressive disorder 3,833 European ancestry female cases, 5,280 European ancestry female controls, 1,481 European ancestry male cases, 4,869 European ancestry male controls NA NR [NR] (imputed) 7 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST012302 Genome-wide genotyping array 15463 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Schizophrenia, bipolar disorder or major depressive disorder x sex interaction 31,567 European ancestry schizophrenia cases,19,924 European ancestry bipolar disorder cases, 15,970 European ancestry major depressive disorder cases, 93,025 European ancestry controls NA NR [NR] (imputed) 15 unipolar depression, schizophrenia, sex interaction measurement, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0000289 GCST012301 Genome-wide genotyping array 160486 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Schizophrenia, bipolar disorder or major depressive disorder 11,361 European ancestry schizophrenia female cases, 20,206 European ancestry schizophrenia male cases, 11,897 European ancestry bipolar disorder female cases, 8,027 European ancestry bipolar disorder male cases, 10,865 European ancestry major depressive disorder female cases, 5,105 major depressive disorder male cases, 46,410 European ancestry female controls, 46,615 European ancestry male controls NA NR [NR] (imputed) 8 unipolar depression, schizophrenia, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0000289 GCST012300 Genome-wide genotyping array 160486 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) 31,567 European ancestry schizophrenia cases,19,924 European ancestry bipolar disorder cases, 15,970 European ancestry major depressive disorder cases, 93,025 European ancestry controls NA NR [NR] (imputed) 22 unipolar depression, schizophrenia, sex interaction measurement, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0000289 GCST012299 Genome-wide genotyping array 160486 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Schizophrenia, bipolar disorder or major depressive disorder x sex interaction 31,567 European ancestry schizophrenia cases,19,924 European ancestry bipolar disorder cases, 15,970 European ancestry major depressive disorder cases, 93,025 European ancestry controls, 1,836 East Asian ancestry schizophrenia cases, 3,383 East Asian ancestry controls NA NR [NR] (imputed) 17 unipolar depression, schizophrenia, sex interaction measurement, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0000289 GCST012298 Genome-wide genotyping array 165705 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Schizophrenia, bipolar disorder or major depressive disorder 11,361 European ancestry schizophrenia female cases, 20,206 European ancestry schizophrenia male cases, 11,897 European ancestry bipolar disorder female cases, 8,027 European ancestry bipolar disorder male cases, 10,865 European ancestry major depressive disorder female cases, 5,105 major depressive disorder male cases, 46,410 European ancestry female controls, 46,615 European ancestry male controls, 686 East Asian ancestry schizophrenia female cases, 1,907 East Asian ancestry female controls, 1,150 East Asian ancestry schizophrenia male cases, 1,476 East Asian ancestry male controls NA NR [NR] (imputed) 13 unipolar depression, schizophrenia, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0000289 GCST012297 Genome-wide genotyping array 165705 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) 31,567 European ancestry schizophrenia cases,19,924 European ancestry bipolar disorder cases, 15,970 European ancestry major depressive disorder cases, 93,025 European ancestry controls, 1,836 East Asian ancestry schizophrenia cases, 3,383 East Asian ancestry controls NA NR [NR] (imputed) 21 unipolar depression, schizophrenia, sex interaction measurement, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0000289 GCST012296 Genome-wide genotyping array 165705 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction 31,567 European ancestry schizophrenia cases,19,924 European ancestry bipolar disorder cases, 5,314 European ancestry recurrent major depressive disorder cases, 78,190 European ancestry controls NA NR [NR] (imputed) 16 unipolar depression, schizophrenia, sex interaction measurement, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0000289 GCST012295 Genome-wide genotyping array 134995 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Schizophrenia, bipolar disorder or recurrent major depressive disorder 11,361 European ancestry schizophrenia female cases, 20,206 European ancestry schizophrenia male cases, 11,897 European ancestry bipolar disorder female cases, 8,027 European ancestry bipolar disorder male cases, 3,833 European ancestry recurrent major depressive disorder female cases, 1,481 recurrent major depressive disorder male cases, 38,937 European ancestry female controls, 29,714 European ancestry male controls NA NR [NR] (imputed) 5 unipolar depression, schizophrenia, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0000289 GCST012294 Genome-wide genotyping array 125456 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction (3df) 31,567 European ancestry schizophrenia cases,19,924 European ancestry bipolar disorder cases, 5,314 European ancestry recurrent major depressive disorder cases, 78,190 European ancestry controls NA NR [NR] (imputed) 19 unipolar depression, schizophrenia, sex interaction measurement, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0000289 GCST012293 Genome-wide genotyping array 134995 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction 31,567 European ancestry schizophrenia cases,19,924 European ancestry bipolar disorder cases, 5,314 European ancestry recurrent major depressive disorder cases, 78,190 European ancestry controls, 1,836 East Asian ancestry schizophrenia cases, 3,383 East Asian ancestry controls NA NR [NR] (imputed) 14 unipolar depression, schizophrenia, sex interaction measurement, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0000289 GCST012292 Genome-wide genotyping array 140214 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Schizophrenia, bipolar disorder or recurrent major depressive disorder 11,361 European ancestry schizophrenia female cases, 20,206 European ancestry schizophrenia male cases, 11,897 European ancestry bipolar disorder female cases, 8,027 European ancestry bipolar disorder male cases, 3,833 European ancestry recurrent major depressive disorder female cases, 1,481 recurrent major depressive disorder male cases, 38,937 European ancestry female controls, 29,714 European ancestry male controls, 686 East Asian ancestry schizophrenia female cases, 1,907 East Asian ancestry female controls, 1,150 East Asian ancestry schizophrenia male cases, 1,476 East Asian ancestry male controls NA NR [NR] (imputed) 7 unipolar depression, schizophrenia, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0000289 GCST012291 Genome-wide genotyping array 130675 2021-09-03 34099189 Blokland GAM 2021-03-23 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34099189 Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction (3df) 31,567 European ancestry schizophrenia cases,19,924 European ancestry bipolar disorder cases, 5,314 European ancestry recurrent major depressive disorder cases, 78,190 European ancestry controls, 1,836 East Asian ancestry schizophrenia cases, 3,383 East Asian ancestry controls NA NR [NR] (imputed) 21 unipolar depression, schizophrenia, sex interaction measurement, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0000289 GCST012290 Genome-wide genotyping array 140214 2021-08-25 33539531 Casares-Marfil D 2021-02-04 Clin Infect Dis www.ncbi.nlm.nih.gov/pubmed/33539531 A genome-wide association study identifies novel susceptibility loci in chronic Chagas cardiomyopathy. Trypanosoma cruzi infection 1,019 Colombian ancestry cases, 1,104 Colombian ancestry controls NA Illumina [7846902] (imputed) 4 Trypanosoma cruzi seropositivity http://www.ebi.ac.uk/efo/EFO_0005530 GCST90026452 Genome-wide genotyping array 2123 2021-08-25 33539531 Casares-Marfil D 2021-02-04 Clin Infect Dis www.ncbi.nlm.nih.gov/pubmed/33539531 A genome-wide association study identifies novel susceptibility loci in chronic Chagas cardiomyopathy. Trypanosoma cruzi infection up to 213 Argentinian ancestry individuals NA Illumina [8408292] (imputed) 0 Trypanosoma cruzi seropositivity http://www.ebi.ac.uk/efo/EFO_0005530 GCST90026453 Genome-wide genotyping array 213 2021-08-25 33539531 Casares-Marfil D 2021-02-04 Clin Infect Dis www.ncbi.nlm.nih.gov/pubmed/33539531 A genome-wide association study identifies novel susceptibility loci in chronic Chagas cardiomyopathy. Chagas cardiomyopathy in Tripanosoma cruzi seropositivity 981 Latin American cases, 1,328 Latin American controls NA Illumina [8218190] (imputed) 3 Chagas cardiomyopathy http://www.ebi.ac.uk/efo/EFO_0005529 GCST90026454 Genome-wide genotyping array 2309 2021-10-18 34021356 Sarnowski C 2021-05-22 Hum Reprod www.ncbi.nlm.nih.gov/pubmed/34021356 Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche. Menarche (age at onset) 19,028 African ancestry individuals 5,148 African ancestry individuals Affymetrix, Illumina [NR] (imputed) 1 age at menarche http://www.ebi.ac.uk/efo/EFO_0004703 GCST012491 Genome-wide genotyping array 19028 2021-10-18 34021356 Sarnowski C 2021-05-22 Hum Reprod www.ncbi.nlm.nih.gov/pubmed/34021356 Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche. Menarche (age at onset) 19,028 African ancestry individuals, 3,205 South Asian ancestry individuals, 2,095 East Asian ancestry individuals, 10,661 Hispanic/Latina individuals, 3,557 individuals NA Affymetrix, Illumina [NR] (imputed) 7 age at menarche http://www.ebi.ac.uk/efo/EFO_0004703 GCST012492 Genome-wide genotyping array 38546 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Cystatin C levels 437,846 European ancestry individuals NA NR [9800000] (imputed) 27 cystatin C measurement http://www.ebi.ac.uk/efo/EFO_0004617 GCST90025945 Genome-wide genotyping array 437846 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Creatinine levels 437,660 European ancestry individuals NA NR [9800000] (imputed) 23 creatinine measurement http://www.ebi.ac.uk/efo/EFO_0004518 GCST90025946 Genome-wide genotyping array 437660 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Serum alkaline phosphatase levels 437,896 European ancestry individuals NA NR [9800000] (imputed) 68 alkaline phosphatase measurement http://www.ebi.ac.uk/efo/EFO_0004533 GCST90025947 Genome-wide genotyping array 437896 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Serum phosphate levels 400,159 European ancestry individuals NA NR [9800000] (imputed) 14 blood phosphate measurement http://www.ebi.ac.uk/efo/EFO_0010972 GCST90025948 Genome-wide genotyping array 400159 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Height 458,235 European ancestry individuals NA NR [9800000] (imputed) 58 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST90025949 Genome-wide genotyping array 458235 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Monocyte count 443,529 European ancestry individuals NA NR [9800000] (imputed) 21 monocyte count http://www.ebi.ac.uk/efo/EFO_0005091 GCST90025950 Genome-wide genotyping array 443529 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Platelet count 444,866 European ancestry individuals NA NR [9800000] (imputed) 46 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST90025951 Genome-wide genotyping array 444866 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Apolipoprotein B levels 435,744 European ancestry individuals NA NR [9800000] (imputed) 29 apolipoprotein B measurement http://www.ebi.ac.uk/efo/EFO_0004615 GCST90025952 Genome-wide genotyping array 435744 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Total cholesterol levels 437,878 European ancestry individuals NA NR [9800000] (imputed) 30 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST90025953 Genome-wide genotyping array 437878 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Direct low density lipoprotein cholesterol levels 437,068 European ancestry individuals NA NR [9800000] (imputed) 27 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST90025954 Genome-wide genotyping array 437068 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Apolipoprotein A1 levels 398,508 European ancestry individuals NA NR [9800000] (imputed) 59 apolipoprotein A 1 measurement http://www.ebi.ac.uk/efo/EFO_0004614 GCST90025955 Genome-wide genotyping array 398508 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. HDL cholesterol levels 400,754 European ancestry individuals NA NR [9800000] (imputed) 65 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST90025956 Genome-wide genotyping array 400754 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Triglyceride levels 437,532 European ancestry individuals NA NR [9800000] (imputed) 36 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST90025957 Genome-wide genotyping array 437532 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Sex hormone-binding globulin levels 397,043 European ancestry individuals NA NR [9800000] (imputed) 22 sex hormone-binding globulin measurement http://www.ebi.ac.uk/efo/EFO_0004696 GCST90025958 Genome-wide genotyping array 397043 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. C-reactive protein levels 436,939 European ancestry individuals NA NR [9800000] (imputed) 15 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST90025959 Genome-wide genotyping array 436939 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Mean platelet volume 445,364 European ancestry individuals NA NR [9800000] (imputed) 55 mean platelet volume http://www.ebi.ac.uk/efo/EFO_0004584 GCST90025960 Genome-wide genotyping array 445364 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Platelet distribution width 445,262 European ancestry individuals NA NR [9800000] (imputed) 35 platelet component distribution width http://www.ebi.ac.uk/efo/EFO_0007984 GCST90025961 Genome-wide genotyping array 445262 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Mean corpuscular hemoglobin concentration 443,081 European ancestry individuals NA NR [9800000] (imputed) 24 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90025962 Genome-wide genotyping array 443081 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Mean corpuscular volume 444,035 European ancestry individuals NA NR [9800000] (imputed) 22 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST90025963 Genome-wide genotyping array 444035 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Red blood cell count 445,305 European ancestry individuals NA NR [9800000] (imputed) 23 erythrocyte count http://www.ebi.ac.uk/efo/EFO_0004305 GCST90025964 Genome-wide genotyping array 445305 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Urate levels 437,354 European ancestry individuals NA NR [9800000] (imputed) 35 urate measurement http://www.ebi.ac.uk/efo/EFO_0004531 GCST90025965 Genome-wide genotyping array 437354 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Gamma glutamyl transferase levels 437,651 European ancestry individuals NA NR [9800000] (imputed) 24 serum gamma-glutamyl transferase measurement http://www.ebi.ac.uk/efo/EFO_0004532 GCST90025966 Genome-wide genotyping array 437651 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Vitamin D levels 418,691 European ancestry individuals NA NR [9800000] (imputed) 7 vitamin D measurement http://www.ebi.ac.uk/efo/EFO_0004631 GCST90025967 Genome-wide genotyping array 418691 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Systolic blood pressure 422,713 European ancestry individuals NA NR [9800000] (imputed) 11 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST90025968 Genome-wide genotyping array 422713 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Hemoglobin levels 445,373 European ancestry individuals NA NR [9800000] (imputed) 19 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST90025969 Genome-wide genotyping array 445373 2021-10-12 34184762 Gao C 2021-06-29 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/34184762 Genome-wide association analysis of serum alanine and aspartate aminotransferase, and the modifying effects of BMI in 388k European individuals. Alanine aminotransferase levels 388,865 European ancestry individuals NA Affymetrix, Illumina [11000000] (imputed) 300 serum alanine aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004735 GCST90025866 Genome-wide genotyping array 388865 2021-10-12 34184762 Gao C 2021-06-29 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/34184762 Genome-wide association analysis of serum alanine and aspartate aminotransferase, and the modifying effects of BMI in 388k European individuals. Aspartate aminotransferase levels 388,865 European ancestry individuals NA Affymetrix, Illumina [11000000] (imputed) 336 aspartate aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004736 GCST90025867 Genome-wide genotyping array 388865 2021-10-12 34184762 Gao C 2021-06-29 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/34184762 Genome-wide association analysis of serum alanine and aspartate aminotransferase, and the modifying effects of BMI in 388k European individuals. Alanine aminotransferase levels x BMI interaction 388,865 European ancestry individuals NA Affymetrix, Illumina [11000000] (imputed) 9 serum alanine aminotransferase measurement, body mass index http://www.ebi.ac.uk/efo/EFO_0004735, http://www.ebi.ac.uk/efo/EFO_0004340 GCST90025868 Genome-wide genotyping array 388865 2021-10-12 34184762 Gao C 2021-06-29 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/34184762 Genome-wide association analysis of serum alanine and aspartate aminotransferase, and the modifying effects of BMI in 388k European individuals. Aspartate aminotransferase levels x BMI interaction 388,865 European ancestry individuals NA Affymetrix, Illumina [11000000] (imputed) 12 aspartate aminotransferase measurement, body mass index http://www.ebi.ac.uk/efo/EFO_0004736, http://www.ebi.ac.uk/efo/EFO_0004340 GCST90025869 Genome-wide genotyping array 388865 2021-08-24 34124712 Sherva R 2021-02-28 Explor Med www.ncbi.nlm.nih.gov/pubmed/34124712 Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes. Cocaine dependence (time to event) 3,554 African American cases, 478 African American controls, 2,712 European ancestry cases, 915 European ancestry controls 572 African American cases, 416 African American controls, 759 European ancestry cases, 1,620 European ancestry controls Illumina [NR] (imputed) 5 cocaine dependence http://www.ebi.ac.uk/efo/EFO_0002610 GCST012225 Genome-wide genotyping array 7659 2021-08-24 34124712 Sherva R 2021-02-28 Explor Med www.ncbi.nlm.nih.gov/pubmed/34124712 Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes. Cocaine dependence (time to event) 3,554 African American cases, 478 African American controls 572 African American cases, 416 African American controls Illumina [NR] (imputed) 1 cocaine dependence http://www.ebi.ac.uk/efo/EFO_0002610 GCST012224 Genome-wide genotyping array 4032 2021-08-24 34124712 Sherva R 2021-02-28 Explor Med www.ncbi.nlm.nih.gov/pubmed/34124712 Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes. Cocaine dependence (time to event) 2,712 European ancestry cases, 915 European ancestry controls 759 European ancestry cases, 1,620 European ancestry controls Illumina [NR] (imputed) 0 cocaine dependence http://www.ebi.ac.uk/efo/EFO_0002610 GCST012223 Genome-wide genotyping array 3627 2021-08-24 34124712 Sherva R 2021-02-28 Explor Med www.ncbi.nlm.nih.gov/pubmed/34124712 Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes. Opioid dependence (time to event) 1,307 African American cases, 974 African American controls 144 African American cases, 354 African American controls Illumina [NR] (imputed) 7 opioid dependence http://www.ebi.ac.uk/efo/EFO_0005611 GCST012222 Genome-wide genotyping array 2281 2021-08-24 34124712 Sherva R 2021-02-28 Explor Med www.ncbi.nlm.nih.gov/pubmed/34124712 Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes. Opioid dependence (time to event) 1,307 African American cases, 974 African American controls, 2,340 European ancestry cases, 768 European ancestry controls 144 African American cases, 354 African American controls, up to 1,551 European ancestry cases, up to 1,393 European ancestry controls Illumina [NR] (imputed) 3 opioid dependence http://www.ebi.ac.uk/efo/EFO_0005611 GCST012221 Genome-wide genotyping array 5389 2021-08-24 34124712 Sherva R 2021-02-28 Explor Med www.ncbi.nlm.nih.gov/pubmed/34124712 Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes. Opioid dependence (time to event) 2,340 European ancestry cases, 768 European ancestry controls up to 1,551 European ancestry cases, up to 1,393 European ancestry controls Illumina [NR] (imputed) 0 opioid dependence http://www.ebi.ac.uk/efo/EFO_0005611 GCST012220 Genome-wide genotyping array 3108 2021-07-29 34177598 Wolking S 2021-06-09 Front Pharmacol www.ncbi.nlm.nih.gov/pubmed/34177598 Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications. Response to levetiracetam in focal epilepsy 258 European ancestry cases, 678 European ancestry controls NA Illumina [NR] (imputed) 3 response to anticonvulsant http://purl.obolibrary.org/obo/GO_0036277 GCST90020112 Genome-wide genotyping array 936 2021-07-29 34177598 Wolking S 2021-06-09 Front Pharmacol www.ncbi.nlm.nih.gov/pubmed/34177598 Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications. Response to sodium channel-Active anticonvulsant in focal epilepsy 910 European ancestry cases, 1,286 European ancestry controls NA Illumina [NR] (imputed) 2 response to anticonvulsant http://purl.obolibrary.org/obo/GO_0036277 GCST90020113 Genome-wide genotyping array 2196 2021-07-29 34177598 Wolking S 2021-06-09 Front Pharmacol www.ncbi.nlm.nih.gov/pubmed/34177598 Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications. Response to lamotrigine in focal epilepsy 334 European ancestry cases, 680 European ancestry controls NA Illumina [NR] (imputed) 3 response to lamotrigine http://www.ebi.ac.uk/efo/EFO_0007661 GCST90020114 Genome-wide genotyping array 1014 2021-07-29 34177598 Wolking S 2021-06-09 Front Pharmacol www.ncbi.nlm.nih.gov/pubmed/34177598 Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications. Response to carbamazepine in focal epilepsy 424 European ancestry cases, 591 European ancestry controls NA Illumina [NR] (imputed) 3 response to carbamazepine http://www.ebi.ac.uk/efo/EFO_0008484 GCST90020115 Genome-wide genotyping array 1015 2021-07-29 34177598 Wolking S 2021-06-09 Front Pharmacol www.ncbi.nlm.nih.gov/pubmed/34177598 Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications. Response to oxcarbazepine in focal epilepsy 98 European ancestry cases, 296 European ancestry controls NA Illumina [NR] (imputed) 4 response to oxcarbazepine http://www.ebi.ac.uk/efo/EFO_0009893 GCST90020116 Genome-wide genotyping array 394 2021-07-29 34177598 Wolking S 2021-06-09 Front Pharmacol www.ncbi.nlm.nih.gov/pubmed/34177598 Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications. Response to phenytoin in focal epilepsy 71 European ancestry cases, 218 European ancestry controls NA Illumina [NR] (imputed) 4 response to phenytoin http://www.ebi.ac.uk/efo/EFO_0006345 GCST90020117 Genome-wide genotyping array 289 2021-07-29 34177598 Wolking S 2021-06-09 Front Pharmacol www.ncbi.nlm.nih.gov/pubmed/34177598 Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications. Response to calcium-channel-Active anticonvulsants in focal epilepsy 214 European ancestry cases, 410 European ancestry controls NA Illumina [NR] (imputed) 3 response to anticonvulsant http://purl.obolibrary.org/obo/GO_0036277 GCST90020118 Genome-wide genotyping array 624 2021-07-29 34177598 Wolking S 2021-06-09 Front Pharmacol www.ncbi.nlm.nih.gov/pubmed/34177598 Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications. Response to valproic acid in focal epilepsy 202 European ancestry cases, 528 European ancestry controls NA Illumina [NR] (imputed) 3 response to anticonvulsant http://purl.obolibrary.org/obo/GO_0036277 GCST90020119 Genome-wide genotyping array 730 2021-07-29 34177598 Wolking S 2021-06-09 Front Pharmacol www.ncbi.nlm.nih.gov/pubmed/34177598 Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications. Response to levetiracetam in epilepsy 343 European ancestry cases, 895 European ancestry controls NA Illumina [NR] (imputed) 2 response to anticonvulsant http://purl.obolibrary.org/obo/GO_0036277 GCST90020120 Genome-wide genotyping array 1238 2021-07-29 34177598 Wolking S 2021-06-09 Front Pharmacol www.ncbi.nlm.nih.gov/pubmed/34177598 Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications. Response to lamotrigine in epilepsy 471 European ancestry cases, 929 European ancestry controls NA Illumina [NR] (imputed) 4 response to lamotrigine http://www.ebi.ac.uk/efo/EFO_0007661 GCST90020121 Genome-wide genotyping array 1400 2021-07-29 34177598 Wolking S 2021-06-09 Front Pharmacol www.ncbi.nlm.nih.gov/pubmed/34177598 Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications. Response to calcium-channel-Active anticonvulsants in epilepsy 690 European ancestry cases, 848 European ancestry controls NA Illumina [NR] (imputed) 1 response to anticonvulsant http://purl.obolibrary.org/obo/GO_0036277 GCST90020122 Genome-wide genotyping array 1538 2021-07-29 34177598 Wolking S 2021-06-09 Front Pharmacol www.ncbi.nlm.nih.gov/pubmed/34177598 Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications. Response to valproic acid in epilepsy 612 European ancestry cases, 690 European ancestry controls NA Illumina [NR] (imputed) 1 response to anticonvulsant http://purl.obolibrary.org/obo/GO_0036277 GCST90020123 Genome-wide genotyping array 1302 2021-07-29 34177598 Wolking S 2021-06-09 Front Pharmacol www.ncbi.nlm.nih.gov/pubmed/34177598 Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications. Response to sodium channel-Active anticonvulsants in focal epilepsy 636 European ancestry cases, 890 European ancestry controls NA Illumina [NR] (imputed) 0 response to anticonvulsant http://purl.obolibrary.org/obo/GO_0036277 GCST90020124 Genome-wide genotyping array 1526 2021-08-13 34315874 Ward LD 2021-07-27 Nat Commun www.ncbi.nlm.nih.gov/pubmed/34315874 GWAS of serum ALT and AST reveals an association of SLC30A10 Thr95Ile with hypermanganesemia symptoms. Extrahepatic cholangiocarcinoma 148 British ancestry cases, 408,035 British ancestry controls NA Affymetrix [11811438] (imputed) 2 extrahepatic bile duct carcinoma http://purl.obolibrary.org/obo/MONDO_0003090 GCST90013662 Genome-wide genotyping array 408183 2021-08-13 34315874 Ward LD 2021-07-27 Nat Commun www.ncbi.nlm.nih.gov/pubmed/34315874 GWAS of serum ALT and AST reveals an association of SLC30A10 Thr95Ile with hypermanganesemia symptoms. Alanine aminotransferase levels 387,859 British ancestry individuals, 10,635 Asian or Asian British individuals, 7,468 Black or Black British individuals, 2,338 Chinese ancestry individuals NA Affymetrix [21347608] (imputed) 104 serum alanine aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004735 GCST90013663 Genome-wide genotyping array 408300 2021-08-13 34315874 Ward LD 2021-07-27 Nat Commun www.ncbi.nlm.nih.gov/pubmed/34315874 GWAS of serum ALT and AST reveals an association of SLC30A10 Thr95Ile with hypermanganesemia symptoms. Aspartate aminotransferase levels 386,570 British ancestry individuals, 10,617 Asian or Asian British individuals, 7,426 Black or Black British individuals, 2,321 Chinese ancestry individuals NA Affymetrix [21347608] (imputed) 103 aspartate aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004736 GCST90013664 Genome-wide genotyping array 406934 2021-10-12 34226506 Cox J 2021-06-29 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/34226506 Genome-wide association study of stimulant dependence. Stimulant dependence 393 European ancestry cases, 5,287 European ancestry controls, 155 African American or Afro-Caribbean cases, 5,603 African American or Afro-Caribbean controls 532 European ancestry cases, 7,103 European ancestry controls, 53 African American or Afro-Caribbean cases, 3,299 African American or Afro-Caribbean controls Illumina [NR] (imputed) 8 drug dependence http://www.ebi.ac.uk/efo/EFO_0003890 GCST90026484 Genome-wide genotyping array 11438 2021-10-12 34226506 Cox J 2021-06-29 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/34226506 Genome-wide association study of stimulant dependence. Stimulant dependence 393 European ancestry cases, 5,278 European ancestry controls 532 European ancestry cases, 7,103 European ancestry controls Illumina [NR] (imputed) 0 drug dependence http://www.ebi.ac.uk/efo/EFO_0003890 GCST90026485 Genome-wide genotyping array 5671 2021-10-12 34226506 Cox J 2021-06-29 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/34226506 Genome-wide association study of stimulant dependence. Stimulant dependence 155 African American or Afro-Caribbean cases, 5,603 African American or Afro-Caribbean controls 53 African American or Afro-Caribbean cases, 3,299 African American or Afro-Caribbean controls Illumina [NR] (imputed) 12 drug dependence http://www.ebi.ac.uk/efo/EFO_0003890 GCST90026486 Genome-wide genotyping array 5758 2021-11-12 33889958 Gurung RL 2021-04-23 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/33889958 Association of genetic variants for plasma LRG1 with rapid decline in kidney function in patients with type 2 diabetes. Leucine-rich alpha-2-glycoprotein 1 levels in type 2 diabetes 983 Chinese ancestry individuals, 420 Malay ancestry individuals, 478 Indian ancestry individuals 1,813 Chinese ancestry individuals Illumina [705416] 1 NA NA GCST90020073 Genome-wide genotyping array 1881 2021-09-29 34031191 Kumar A 2021-05-24 Neurology www.ncbi.nlm.nih.gov/pubmed/34031191 Association of SUMOlation Pathway Genes With Stroke in a Genome-wide Association Study in India. Stroke 1,255 Indian ancestry cases, 2,154 Indian ancestry controls 211 South Asian ancestry cases, 7,417 South Asian ancestry controls Illumina [7827597] (imputed) 0 stroke http://www.ebi.ac.uk/efo/EFO_0000712 GCST90020238 Genome-wide genotyping array 3409 2021-09-29 34031191 Kumar A 2021-05-24 Neurology www.ncbi.nlm.nih.gov/pubmed/34031191 Association of SUMOlation Pathway Genes With Stroke in a Genome-wide Association Study in India. Stroke (ischemic) 1,077 Indian ancestry cases, 2,154 Indian ancestry controls 98 South Asian ancestry cases, 7,421 South Asian ancestry controls Illumina [up to 7827597] (imputed) 0 Ischemic stroke http://purl.obolibrary.org/obo/HP_0002140 GCST90020239 Genome-wide genotyping array 3231 2021-09-29 34031191 Kumar A 2021-05-24 Neurology www.ncbi.nlm.nih.gov/pubmed/34031191 Association of SUMOlation Pathway Genes With Stroke in a Genome-wide Association Study in India. Large artery stroke 350 Indian ancestry cases, 2,154 Indian ancestry controls NA Illumina [up to 7827597] (imputed) 31 large artery stroke http://www.ebi.ac.uk/efo/EFO_0005524 GCST90020240 Genome-wide genotyping array 2504 2021-09-29 34031191 Kumar A 2021-05-24 Neurology www.ncbi.nlm.nih.gov/pubmed/34031191 Association of SUMOlation Pathway Genes With Stroke in a Genome-wide Association Study in India. Small vessel stroke 333 Indian ancestry cases, 2,154 Indian ancestry controls NA Illumina [7827597] (imputed) 43 small vessel stroke http://www.ebi.ac.uk/efo/EFO_1001504 GCST90020241 Genome-wide genotyping array 2487 2021-09-29 34031191 Kumar A 2021-05-24 Neurology www.ncbi.nlm.nih.gov/pubmed/34031191 Association of SUMOlation Pathway Genes With Stroke in a Genome-wide Association Study in India. Ischemic stroke (cardioembolic) 174 Indian ancestry cases, 2,154 Indian ancestry controls NA Illumina [up to 7827597] (imputed) 61 cardioembolic stroke http://www.ebi.ac.uk/efo/EFO_1001976 GCST90020242 Genome-wide genotyping array 2328 2021-09-29 34031191 Kumar A 2021-05-24 Neurology www.ncbi.nlm.nih.gov/pubmed/34031191 Association of SUMOlation Pathway Genes With Stroke in a Genome-wide Association Study in India. Stroke (hemorhagic) 178 Indian ancestry cases, 2,154 Indian ancestry controls 25 South Asian ancestry cases, 7,424 South Asian ancestry controls Illumina [up to 7827597] (imputed) 0 stroke http://www.ebi.ac.uk/efo/EFO_0000712 GCST90020243 Genome-wide genotyping array 2332 2021-10-18 34272439 Foo H 2021-07-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34272439 Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank. Brain functional connectivity measurement (global efficiency) 18,445 British ancestry individuals NA Affymetrix [9926107] (imputed) 1 functional brain measurement http://www.ebi.ac.uk/efo/EFO_0007849 GCST90026613 Genome-wide genotyping array 18445 2021-10-18 34272439 Foo H 2021-07-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34272439 Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank. Brain functional connectivity measurement (characteristic path length) 18,445 British ancestry individuals NA Affymetrix [9926107] (imputed) 1 functional brain measurement http://www.ebi.ac.uk/efo/EFO_0007849 GCST90026614 Genome-wide genotyping array 18445 2021-10-18 34272439 Foo H 2021-07-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34272439 Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank. Brain functional connectivity measurement (louvain modularity) 18,445 British ancestry individuals NA Affymetrix [9926107] (imputed) 1 functional brain measurement http://www.ebi.ac.uk/efo/EFO_0007849 GCST90026615 Genome-wide genotyping array 18445 2021-10-18 34272439 Foo H 2021-07-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34272439 Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank. Brain functional connectivity measurement (transitivity) 18,445 British ancestry individuals NA Affymetrix [9926107] (imputed) 0 functional brain measurement http://www.ebi.ac.uk/efo/EFO_0007849 GCST90026616 Genome-wide genotyping array 18445 2021-10-18 34272439 Foo H 2021-07-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34272439 Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank. Brain functional connectivity measurement (local efficiency default) 18,445 British ancestry individuals NA Affymetrix [9926107] (imputed) 1 functional brain measurement http://www.ebi.ac.uk/efo/EFO_0007849 GCST90026617 Genome-wide genotyping array 18445 2021-10-18 34272439 Foo H 2021-07-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34272439 Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank. Brain functional connectivity measurement (local efficiency dorsal attention) 18,445 British ancestry individuals NA Affymetrix [9926107] (imputed) 0 functional brain measurement http://www.ebi.ac.uk/efo/EFO_0007849 GCST90026618 Genome-wide genotyping array 18445 2021-10-18 34272439 Foo H 2021-07-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34272439 Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank. Brain functional connectivity measurement (local efficiency frontoparietal) 18,445 British ancestry individuals NA Affymetrix [9926107] (imputed) 0 functional brain measurement http://www.ebi.ac.uk/efo/EFO_0007849 GCST90026619 Genome-wide genotyping array 18445 2021-10-18 34272439 Foo H 2021-07-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34272439 Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank. Brain functional connectivity measurement (local efficiency limbic) 18,445 British ancestry individuals NA Affymetrix [9926107] (imputed) 0 functional brain measurement http://www.ebi.ac.uk/efo/EFO_0007849 GCST90026620 Genome-wide genotyping array 18445 2021-10-18 34272439 Foo H 2021-07-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34272439 Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank. Brain functional connectivity measurement (local efficiency salience) 18,445 British ancestry individuals NA Affymetrix [9926107] (imputed) 0 functional brain measurement http://www.ebi.ac.uk/efo/EFO_0007849 GCST90026621 Genome-wide genotyping array 18445 2021-10-18 34272439 Foo H 2021-07-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34272439 Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank. Brain functional connectivity measurement (local efficiency somatomotor) 18,445 British ancestry individuals NA Affymetrix [9926107] (imputed) 1 functional brain measurement http://www.ebi.ac.uk/efo/EFO_0007849 GCST90026622 Genome-wide genotyping array 18445 2021-10-18 34272439 Foo H 2021-07-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34272439 Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank. Brain functional connectivity measurement (local effieiency visual) 18,445 British ancestry individuals NA Affymetrix [9926107] (imputed) 0 functional brain measurement http://www.ebi.ac.uk/efo/EFO_0007849 GCST90026623 Genome-wide genotyping array 18445 2021-10-18 34272439 Foo H 2021-07-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34272439 Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank. Brain functional connectivity measurement (strength default) 18,445 British ancestry individuals NA Affymetrix [9926107] (imputed) 1 functional brain measurement http://www.ebi.ac.uk/efo/EFO_0007849 GCST90026624 Genome-wide genotyping array 18445 2021-10-18 34272439 Foo H 2021-07-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34272439 Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank. Brain functional connectivity measurement (strength dorsal attention) 18,445 British ancestry individuals NA Affymetrix [9926107] (imputed) 0 functional brain measurement http://www.ebi.ac.uk/efo/EFO_0007849 GCST90026625 Genome-wide genotyping array 18445 2021-10-18 34272439 Foo H 2021-07-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34272439 Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank. Brain functional connectivity measurement (strength frontoparietal) 18,445 British ancestry individuals NA Affymetrix [9926107] (imputed) 0 functional brain measurement http://www.ebi.ac.uk/efo/EFO_0007849 GCST90026626 Genome-wide genotyping array 18445 2021-10-18 34272439 Foo H 2021-07-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34272439 Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank. Brain functional connectivity measurement (strength limbic) 18,445 British ancestry individuals NA Affymetrix [9926107] (imputed) 1 functional brain measurement http://www.ebi.ac.uk/efo/EFO_0007849 GCST90026627 Genome-wide genotyping array 18445 2021-10-18 34272439 Foo H 2021-07-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34272439 Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank. Brain functional connectivity measurement (strength salience) 18,445 British ancestry individuals NA Affymetrix [9926107] (imputed) 1 functional brain measurement http://www.ebi.ac.uk/efo/EFO_0007849 GCST90026628 Genome-wide genotyping array 18445 2021-10-18 34272439 Foo H 2021-07-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34272439 Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank. Brain functional connectivity measurement (strength somatomotor) 18,445 British ancestry individuals NA Affymetrix [9926107] (imputed) 1 functional brain measurement http://www.ebi.ac.uk/efo/EFO_0007849 GCST90026629 Genome-wide genotyping array 18445 2021-10-18 34272439 Foo H 2021-07-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34272439 Novel genetic variants associated with brain functional networks in 18,445 adults from the UK Biobank. Brain functional connectivity measurement (strength visual) 18,445 British ancestry individuals NA Affymetrix [9926108] (imputed) 0 functional brain measurement http://www.ebi.ac.uk/efo/EFO_0007849 GCST90026630 Genome-wide genotyping array 18445 2021-07-07 34111113 Green HD 2021-06-10 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34111113 A genome-wide association study identifies 5 loci associated with frozen shoulder and implicates diabetes as a causal risk factor. Frozen shoulder 451,099 European ancestry individuals NA NR [8274682] (imputed) 0 frozen shoulder http://www.ebi.ac.uk/efo/EFO_1000941 GCST90000512 Genome-wide genotyping array 451099 2021-07-07 34111113 Green HD 2021-06-10 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34111113 A genome-wide association study identifies 5 loci associated with frozen shoulder and implicates diabetes as a causal risk factor. Frozen shoulder 627,998 European ancestry individuals NA NR [16689279] (imputed) 5 frozen shoulder http://www.ebi.ac.uk/efo/EFO_1000941 GCST90000513 Genome-wide genotyping array 627998 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (sialyl-lacto-N-tetraose c) 395 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 0 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027220 Genome-wide genotyping array 395 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (sialyl-lacto-N-tetraose c) in non-secretors 90 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 1 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027229 Genome-wide genotyping array 90 2021-08-13 34128465 Liu Y 2021-06-15 Elife www.ncbi.nlm.nih.gov/pubmed/34128465 Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning. Liver volume 32,860 European ancestry individuals NA Affymetrix [9390170] (imputed) 12 NA NA GCST90016666 Genome-wide genotyping array 32860 2021-08-13 34128465 Liu Y 2021-06-15 Elife www.ncbi.nlm.nih.gov/pubmed/34128465 Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning. Spleen volume 32,860 European ancestry individuals NA Affymetrix [9390170] (imputed) 40 NA NA GCST90016667 Genome-wide genotyping array 32860 2021-08-13 34128465 Liu Y 2021-06-15 Elife www.ncbi.nlm.nih.gov/pubmed/34128465 Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning. Lung volume 32,860 European ancestry individuals NA Affymetrix [9390170] (imputed) 7 NA NA GCST90016668 Genome-wide genotyping array 32860 2021-08-13 34128465 Liu Y 2021-06-15 Elife www.ncbi.nlm.nih.gov/pubmed/34128465 Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning. Pancreas volume 31,758 European ancestry individuals NA Affymetrix [9390170] (imputed) 17 NA NA GCST90016669 Genome-wide genotyping array 31758 2021-08-13 34128465 Liu Y 2021-06-15 Elife www.ncbi.nlm.nih.gov/pubmed/34128465 Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning. Kidney volume 32,860 European ancestry individuals NA Affymetrix [9390170] (imputed) 12 NA NA GCST90016670 Genome-wide genotyping array 32860 2021-08-13 34128465 Liu Y 2021-06-15 Elife www.ncbi.nlm.nih.gov/pubmed/34128465 Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning. Visceral adipose tissue volume 32,860 European ancestry individuals NA Affymetrix [9390170] (imputed) 6 visceral adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004765 GCST90016671 Genome-wide genotyping array 32860 2021-08-13 34128465 Liu Y 2021-06-15 Elife www.ncbi.nlm.nih.gov/pubmed/34128465 Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning. Abdominal subcutaneous adipose tissue volume 32,860 European ancestry individuals NA Affymetrix [9390170] (imputed) 2 subcutaneous adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004766 GCST90016672 Genome-wide genotyping array 32860 2021-08-13 34128465 Liu Y 2021-06-15 Elife www.ncbi.nlm.nih.gov/pubmed/34128465 Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning. Percent liver fat 32,858 European ancestry individuals NA Affymetrix [9390170] (imputed) 12 liver fat measurement http://www.ebi.ac.uk/efo/EFO_0010821 GCST90016673 Genome-wide genotyping array 32858 2021-08-13 34128465 Liu Y 2021-06-15 Elife www.ncbi.nlm.nih.gov/pubmed/34128465 Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning. Liver iron content 32,858 European ancestry individuals NA Affymetrix [9390170] (imputed) 23 liver iron measurement http://www.ebi.ac.uk/efo/EFO_0010056 GCST90016674 Genome-wide genotyping array 32858 2021-08-13 34128465 Liu Y 2021-06-15 Elife www.ncbi.nlm.nih.gov/pubmed/34128465 Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning. Pancreas fat 25,617 European ancestry individuals NA Affymetrix [9390170] (imputed) 10 NA NA GCST90016675 Genome-wide genotyping array 25617 2021-08-13 34128465 Liu Y 2021-06-15 Elife www.ncbi.nlm.nih.gov/pubmed/34128465 Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning. Pancreas iron content 25,617 European ancestry individuals NA Affymetrix [9390170] (imputed) 1 iron biomarker measurement http://www.ebi.ac.uk/efo/EFO_0004461 GCST90016676 Genome-wide genotyping array 25617 2021-07-07 34127828 Bolin K 2021-06-14 Genes Immun www.ncbi.nlm.nih.gov/pubmed/34127828 Variants in BANK1 are associated with lupus nephritis of European ancestry. Lupus nephritis in systemic lupus erythematosus 377 European ancestry cases, 714 European ancestry controls 570 Europen ancestry cases, 1,225 European ancestry controls Illumina [112815] 1 lupus nephritis http://www.ebi.ac.uk/efo/EFO_0005761 GCST012003 Targeted genotyping array [ImmunoChip] 1091 2021-10-19 34290314 Brandes N 2021-07-21 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34290314 Genetic association studies of alterations in protein function expose recessive effects on cancer predisposition. Cancer 56,634 White British ancestry cases, 218,196 White British ancestry controls NA NR [688737] 79 cancer http://www.ebi.ac.uk/efo/EFO_0000311 GCST90027051 Genome-wide genotyping array 274830 2021-10-19 34290314 Brandes N 2021-07-21 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34290314 Genetic association studies of alterations in protein function expose recessive effects on cancer predisposition. Breast cancer 10,682 White British ancestry cases, 138,504 White British ancestry controls NA NR [682398] 58 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST90027052 Genome-wide genotyping array 149186 2021-10-19 34290314 Brandes N 2021-07-21 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34290314 Genetic association studies of alterations in protein function expose recessive effects on cancer predisposition. Chronic lymphocytic leukemia 764 White British ancestry cases, 272,079 White British ancestry controls NA NR [663083] 34 chronic lymphocytic leukemia http://www.ebi.ac.uk/efo/EFO_0000095 GCST90027053 Genome-wide genotyping array 272843 2021-10-19 34290314 Brandes N 2021-07-21 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34290314 Genetic association studies of alterations in protein function expose recessive effects on cancer predisposition. Colorectal cancer 3,351 White British ancestry cases, 271,479 White British ancestry controls NA NR [675173] 17 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST90027054 Genome-wide genotyping array 274830 2021-10-19 34290314 Brandes N 2021-07-21 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34290314 Genetic association studies of alterations in protein function expose recessive effects on cancer predisposition. Epithelial ovarian cancer 1,112 White British ancestry cases, 147,944 White British ancestry controls NA NR [666300] 25 ovarian carcinoma http://www.ebi.ac.uk/efo/EFO_0001075 GCST90027055 Genome-wide genotyping array 149056 2021-10-19 34290314 Brandes N 2021-07-21 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34290314 Genetic association studies of alterations in protein function expose recessive effects on cancer predisposition. Lung cancer 2,479 White British ancestry cases, 272,351 White British ancestry controls NA NR [673172] 21 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST90027056 Genome-wide genotyping array 274830 2021-10-19 34290314 Brandes N 2021-07-21 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34290314 Genetic association studies of alterations in protein function expose recessive effects on cancer predisposition. Melanoma 3,122 White British ancestry cases, 271,708 White British ancestry controls NA NR [674885] 56 melanoma http://www.ebi.ac.uk/efo/EFO_0000756 GCST90027057 Genome-wide genotyping array 274830 2021-10-19 34290314 Brandes N 2021-07-21 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34290314 Genetic association studies of alterations in protein function expose recessive effects on cancer predisposition. Non-melanoma skin cancer 18,944 White British ancestry cases, 255,886 White British ancestry controls NA NR [685523] 157 non-melanoma skin carcinoma http://www.ebi.ac.uk/efo/EFO_0009260 GCST90027058 Genome-wide genotyping array 274830 2021-10-19 34290314 Brandes N 2021-07-21 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34290314 Genetic association studies of alterations in protein function expose recessive effects on cancer predisposition. Pancreatic cancer 768 White British ancestry cases, 264,559 White British ancestry controls NA NR [663102] 35 pancreatic carcinoma http://www.ebi.ac.uk/efo/EFO_0002618 GCST90027059 Genome-wide genotyping array 265327 2021-10-19 34290314 Brandes N 2021-07-21 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34290314 Genetic association studies of alterations in protein function expose recessive effects on cancer predisposition. Prostate cancer 7,438 White British ancestry cases, 118,206 White British ancestry controls NA NR [680312] 82 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST90027060 Genome-wide genotyping array 125644 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (2'-fucosyllactose) 395 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 2 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027203 Genome-wide genotyping array 395 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (3'-fucosyllactose) 395 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 0 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027219 Genome-wide genotyping array 395 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (3'-fucosyllactose) in secretors 305 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 1 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027222 Genome-wide genotyping array 305 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (3'-sialyllactose) 395 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 0 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027214 Genome-wide genotyping array 395 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (6'-sialyllactose) 395 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 0 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027215 Genome-wide genotyping array 395 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (difucosyllacto-N-hexaose) 395 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 0 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027221 Genome-wide genotyping array 395 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (difucosyllacto-N-hexaose) in non-secretors 90 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 1 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027227 Genome-wide genotyping array 90 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (difucosyllacto-N-tetrose) 395 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 1 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027205 Genome-wide genotyping array 395 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (difucosyllacto-N-tetrose) in secretors 305 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 1 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027223 Genome-wide genotyping array 305 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (difucosyllactose) 395 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 1 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027204 Genome-wide genotyping array 395 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (disialyllacto-N-hexaose) 395 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 0 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027216 Genome-wide genotyping array 395 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (disialyllacto-N-tetraose) 395 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 0 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027217 Genome-wide genotyping array 395 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (fucodisialyllacto-N-hexaose) 395 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 1 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027206 Genome-wide genotyping array 395 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (fucosyllacto-N-hexaose) 395 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 2 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027207 Genome-wide genotyping array 395 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (lacto-N-fucopentaose I) 395 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 1 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027208 Genome-wide genotyping array 395 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (lacto-N-fucopentaose I) in secretors 305 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 1 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027224 Genome-wide genotyping array 305 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (lacto-N-fucopentaose II) 395 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 2 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027209 Genome-wide genotyping array 395 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (lacto-N-fucopentaose II) in secretors 305 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 1 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027225 Genome-wide genotyping array 305 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (lacto-N-fucopentaose III) 395 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 11 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027210 Genome-wide genotyping array 395 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (lacto-N-fucopentaose III) in non-secretors 90 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 44 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027228 Genome-wide genotyping array 90 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (lacto-N-fucopentaose III) in secretors 305 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 11 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027226 Genome-wide genotyping array 305 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (lacto-N-hexaose) 395 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 2 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027211 Genome-wide genotyping array 395 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (lacto-N-neotetraose) 395 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 0 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027218 Genome-wide genotyping array 395 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (lacto-N-tetrose) 395 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 1 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027212 Genome-wide genotyping array 395 2021-09-10 33831438 Williams JE 2021-04-05 Genomics www.ncbi.nlm.nih.gov/pubmed/33831438 Key genetic variants associated with variation of milk oligosaccharides from diverse human populations. Human milk oligosaccharide concentration (sialyl-lacto-N-tetraose b) 395 European, Sub-Saharan African, Hispanic or unknown ancestry individuals NA Illumina [1128286] 1 breast milk measurement http://www.ebi.ac.uk/efo/EFO_0009092 GCST90027213 Genome-wide genotyping array 395 2021-11-15 34202464 Wang M 2021-06-24 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/34202464 Genomic Association vs. Serological Determination of ABO Blood Types in a Chinese Cohort, with Application in Mendelian Randomization. ABO blood group (O vs non-O) up to 356 Han Chinese ancestry individuals with O blood group, up to 622 Han Chinese ancestry individuals with non-O blood group NA Affymetrix [733907] 2 NA NA GCST012522 Genome-wide genotyping array 978 2021-11-15 34202464 Wang M 2021-06-24 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/34202464 Genomic Association vs. Serological Determination of ABO Blood Types in a Chinese Cohort, with Application in Mendelian Randomization. ABO blood group (A vs non-A) up to 322 Han Chinese ancestry individuals with A blood group, up to 686 Han Chinese ancestry individuals with non-A blood group NA Affymetrix [733907] 2 NA NA GCST012521 Genome-wide genotyping array 1008 2021-11-15 34202464 Wang M 2021-06-24 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/34202464 Genomic Association vs. Serological Determination of ABO Blood Types in a Chinese Cohort, with Application in Mendelian Randomization. ABO blood group (B vs non-B) up to 253 Han Chinese ancestry individuals with B blood group, up to 755 Han Chinese ancestry individuals with non-B blood group NA Affymetrix [733907] 2 NA NA GCST012520 Genome-wide genotyping array 1008 2021-11-15 34202464 Wang M 2021-06-24 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/34202464 Genomic Association vs. Serological Determination of ABO Blood Types in a Chinese Cohort, with Application in Mendelian Randomization. ABO blood group (AB vs non-AB) up to 77 Han Chinese ancestry individuals with AB blood group, up to 931 Han Chinese ancestry individuals with non-AB blood group NA Affymetrix [733907] 2 NA NA GCST012519 Genome-wide genotyping array 1008 2021-11-15 34202464 Wang M 2021-06-24 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/34202464 Genomic Association vs. Serological Determination of ABO Blood Types in a Chinese Cohort, with Application in Mendelian Randomization. ABO blood group (A vs O) up to 322 Han Chinese ancestry individuals with A blood group, up to 356 Han Chinese ancestry individuals with A blood group NA Affymetrix [733907] 2 NA NA GCST012518 Genome-wide genotyping array 678 2021-11-15 34202464 Wang M 2021-06-24 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/34202464 Genomic Association vs. Serological Determination of ABO Blood Types in a Chinese Cohort, with Application in Mendelian Randomization. ABO blood group (B vs O) up to 235 Han Chinese ancestry individuals with B blood group, up to 356 Han Chinese ancestry individuals with O blood group NA Affymetrix [733907] 2 NA NA GCST012517 Genome-wide genotyping array 591 2021-11-15 34202464 Wang M 2021-06-24 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/34202464 Genomic Association vs. Serological Determination of ABO Blood Types in a Chinese Cohort, with Application in Mendelian Randomization. ABO blood group (AB vs O) up to 77 Han Chinese ancestry individuals with AB blood group, up to 356 individuals with O blood group NA Affymetrix [733907] 2 NA NA GCST012516 Genome-wide genotyping array 433 2021-07-07 34127677 Choquet H 2021-06-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/34127677 A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Cataracts 28,092 non-Hispanic White ancestry cases, 50,487 non-Hispanic White ancestry controls, 2,233 East Asian ancestry cases, 7,023 East Asian ancestry controls, 2,149 Hispanic/Latino cases, 6,620 Hispanic/Latino controls, 815 African American cases, 2,368 African American controls, 31,852 European ancestry cases, 428,084 European ancestry controls, 757 African ancestry cases, 7,897 African ancestry controls, 1,278 South Asian ancestry cases, 8,571 South Asian ancestry controls, 668 other admixed cases, 7,349 other admixed controls 313,278 European ancestry cases, 2,210,509 European ancestry controls, 7,715 African American cases, 120,390 African American controls, 3,934 East Asian ancestry cases, 104,766 East Asian ancestry controls, 21,408 Latino cases, 425,544 Latino controls, 874 South Asian ancestry cases, 26,037 South Asian ancestry controls Affymetrix [9869154] (imputed) 43 cataract http://www.ebi.ac.uk/efo/EFO_0001059 GCST90014268 Genome-wide genotyping array 586243 2021-07-07 34127677 Choquet H 2021-06-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/34127677 A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Cataracts 28,092 non-Hispanic White ancestry cases, 50,487 non-Hispanic White ancestry controls, 31,852 European ancestry cases, 428,084 European ancestry controls NA Affymetrix [9869154] (imputed) 49 cataract http://www.ebi.ac.uk/efo/EFO_0001059 GCST012012 Genome-wide genotyping array 538515 2021-07-07 34127677 Choquet H 2021-06-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/34127677 A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Cataracts 38,996 female cases, 283,185 female controls, 28,848 male cases, 234,414 male controls 211,030 female cases, 1,623,785 female controls, 136,179 male cases, 1,263,461 male controls Affymetrix [9869154] (imputed) 26 cataract http://www.ebi.ac.uk/efo/EFO_0001059 GCST012013 Genome-wide genotyping array 585443 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (XELOX,Cetuximab) (Neutropenia) 348 European ancestry individuals NA NR [3560566] (imputed) 0 neutropenia, chemotherapy-induced cytotoxicity measurement http://purl.obolibrary.org/obo/MONDO_0001475, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017216 Genome-wide genotyping array 348 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX,Cetuximab) (Neutropenia) 360 European ancestry individuals NA NR [4178858] (imputed) 1 neutropenia, chemotherapy-induced cytotoxicity measurement http://purl.obolibrary.org/obo/MONDO_0001475, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017218 Genome-wide genotyping array 360 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX) (Hand foot syndrome) 385 European ancestry individuals NA NR [3841701] (imputed) 1 Hand-foot syndrome, chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_1001893, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017221 Genome-wide genotyping array 385 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX,Cetuximab) (Hand foot syndrome) 360 European ancestry individuals NA NR [4178072] (imputed) 0 Hand-foot syndrome, chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_1001893, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017222 Genome-wide genotyping array 360 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (XELOX) 707 European ancestry individuals NA NR [4986536] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017223 Genome-wide genotyping array 707 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX) (Sepsis) 385 European ancestry individuals NA NR [4145880] (imputed) 0 chemotherapy-induced cytotoxicity measurement, Sepsis http://www.ebi.ac.uk/efo/EFO_0010978, http://purl.obolibrary.org/obo/HP_0100806 GCST90017227 Genome-wide genotyping array 385 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX,Cetuximab) (Sepsis) 360 European ancestry individuals NA NR [4174431] (imputed) 0 chemotherapy-induced cytotoxicity measurement, Sepsis http://www.ebi.ac.uk/efo/EFO_0010978, http://purl.obolibrary.org/obo/HP_0100806 GCST90017228 Genome-wide genotyping array 360 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (XELOX) (Rash) 707 European ancestry individuals NA NR [3948970] (imputed) 0 chemotherapy-induced cytotoxicity measurement, exanthem http://www.ebi.ac.uk/efo/EFO_0010978, http://www.ebi.ac.uk/efo/EFO_1000697 GCST90017229 Genome-wide genotyping array 707 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (XELOX, Cetuximab) (Rash) 348 European ancestry individuals NA NR [4178858] (imputed) 0 chemotherapy-induced cytotoxicity measurement, exanthem http://www.ebi.ac.uk/efo/EFO_0010978, http://www.ebi.ac.uk/efo/EFO_1000697 GCST90017230 Genome-wide genotyping array 348 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX,Cetuximab) (Rash) 360 European ancestry individuals NA NR [4178858] (imputed) 0 chemotherapy-induced cytotoxicity measurement, exanthem http://www.ebi.ac.uk/efo/EFO_0010978, http://www.ebi.ac.uk/efo/EFO_1000697 GCST90017231 Genome-wide genotyping array 360 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX) (Neutropenia) 385 European ancestry individuals NA NR [4178853] (imputed) 0 neutropenia, chemotherapy-induced cytotoxicity measurement http://purl.obolibrary.org/obo/MONDO_0001475, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017217 Genome-wide genotyping array 385 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (XELOX) (Hand foot syndrome) 707 European ancestry individuals NA NR [4178084] (imputed) 0 Hand-foot syndrome, chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_1001893, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017219 Genome-wide genotyping array 707 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (XELOX,Cetuximab) (Hand foot syndrome) 348 European ancestry individuals NA NR [4178292] (imputed) 0 Hand-foot syndrome, chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_1001893, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017220 Genome-wide genotyping array 348 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (XELOX,Cetuximab) 348 European ancestry individuals NA NR [4986536] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017224 Genome-wide genotyping array 348 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX) 385 European ancestry individuals NA NR [4986536] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017225 Genome-wide genotyping array 385 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX, Cetuximab) 360 European ancestry individuals NA NR [4986536] (imputed) 0 chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017226 Genome-wide genotyping array 360 2021-07-29 34262104 Meijer AJM 2021-07-14 NPJ Precis Oncol www.ncbi.nlm.nih.gov/pubmed/34262104 TCERG1L allelic variation is associated with cisplatin-induced hearing loss in childhood cancer, a PanCareLIFE study. Cisplatin-induced hearing loss in childhood cancer 168 European ancestry, African American or Afro-Caribbean, Hispanic or Latin American child cases, 222 European, African American or Afro-Caribbean, Hispanic or Latin American ancestry child controls 209 child cases, 171 child controls Illumina [673489] (imputed) 1 ototoxicity, hearing loss, response to cisplatin http://www.ebi.ac.uk/efo/EFO_0006951, http://www.ebi.ac.uk/efo/EFO_0004238, http://purl.obolibrary.org/obo/GO_0072718 GCST90013831 Genome-wide genotyping array 390 2021-10-18 34337532 Fantus RJ 2021-05-25 Eur Urol Open Sci www.ncbi.nlm.nih.gov/pubmed/34337532 Genetic Susceptibility for Low Testosterone in Men and Its Implications in Biology and Screening: Data from the UK Biobank. Low testosterone levels 13,409 European ancestry male cases, 98,267 European ancestry male controls 4,426 European ancestry male cases, 32,800 European ancestry male controls NR [8853336] (imputed) 42 testosterone measurement http://www.ebi.ac.uk/efo/EFO_0004908 GCST90026655 Genome-wide genotyping array 111676 2021-09-20 34286861 Trendowski MR 2021-07-19 Cancer www.ncbi.nlm.nih.gov/pubmed/34286861 Clinical and genetic risk factors for radiation-associated ototoxicity: A report from the Childhood Cancer Survivor Study and the St. Jude Lifetime Cohort. Tinnitus in cranial radiation therapy-treated pediatric cancer survivors 146 European ancestry cases, 1,845 European ancestry controls 106 European ancestry cases, 846 European ancestry controls NR [9643440] (imputed) 0 Tinnitus, response to cranial radiation therapy http://purl.obolibrary.org/obo/HP_0000360, http://www.ebi.ac.uk/efo/EFO_0010950 GCST90027272 Genome-wide genotyping array 1991 2021-09-20 34286861 Trendowski MR 2021-07-19 Cancer www.ncbi.nlm.nih.gov/pubmed/34286861 Clinical and genetic risk factors for radiation-associated ototoxicity: A report from the Childhood Cancer Survivor Study and the St. Jude Lifetime Cohort. Hearing loss in cranial radiation therapy-treated pediatric cancer survivors 270 European ancestry cases, 1,928 European ancestry controls 156 European ancestry cases, 175 European ancestry controls NR [9696169] (imputed) 0 hearing loss, response to cranial radiation therapy http://www.ebi.ac.uk/efo/EFO_0004238, http://www.ebi.ac.uk/efo/EFO_0010950 GCST90027273 Genome-wide genotyping array 2198 2021-07-27 33276381 Cheng CF 2020-12-04 Am J Hypertens www.ncbi.nlm.nih.gov/pubmed/33276381 Genome-wide and candidate gene association analyses identify a 14-SNPs combination for hypertension in patients with type 2 diabetes. Hypertension in type 2 diabetes 454 Han Chinese ancestry cases, 545 Han Chinese ancestry controls 563 Han Chinese ancestry cases, 359 Han Chinese ancestry controls Affymetrix, Illumina [NR] (imputed) 2 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST012136 Genome-wide genotyping array 999 2021-10-04 34047840 Vicuna L 2021-05-28 Hum Genet www.ncbi.nlm.nih.gov/pubmed/34047840 Novel loci and mapuche genetic ancestry are associated with pubertal growth traits in Chilean boys. Age at peak height velocity 440 Chilean boys, 464 Chilean girls NA Illumina [774433] (imputed) 1 growth rate measurement, age at assessment http://www.ebi.ac.uk/efo/EFO_0010572, http://www.ebi.ac.uk/efo/EFO_0008007 GCST012433 Genome-wide genotyping array 904 2021-10-04 34047840 Vicuna L 2021-05-28 Hum Genet www.ncbi.nlm.nih.gov/pubmed/34047840 Novel loci and mapuche genetic ancestry are associated with pubertal growth traits in Chilean boys. Height at time of age with peak height velocity 440 Chilean boys, 464 Chilean girls NA Illumina [774433] (imputed) 0 growth rate measurement, age at assessment, body height http://www.ebi.ac.uk/efo/EFO_0010572, http://www.ebi.ac.uk/efo/EFO_0008007, http://www.ebi.ac.uk/efo/EFO_0004339 GCST012432 Genome-wide genotyping array 904 2021-10-04 34047840 Vicuna L 2021-05-28 Hum Genet www.ncbi.nlm.nih.gov/pubmed/34047840 Novel loci and mapuche genetic ancestry are associated with pubertal growth traits in Chilean boys. Peak height velocity 440 Chilean boys, 464 Chilean girls NA Illumina [774433] (imputed) 7 growth rate measurement http://www.ebi.ac.uk/efo/EFO_0010572 GCST012434 Genome-wide genotyping array 904 2021-10-11 34184781 O'Connor E 2021-06-29 Ann Neurol www.ncbi.nlm.nih.gov/pubmed/34184781 Genome Wide Association Study Identifies Risk Loci For Cluster Headache. Cluster headache 1,443 European ancestry cases, 6,748 European ancestry controls NA Illumina [NR] (imputed) 4 Cluster headache http://purl.obolibrary.org/obo/HP_0012199 GCST012478 Genome-wide genotyping array 8191 2021-07-28 34177493 Mountford HS 2021-06-09 Front Hum Neurosci www.ncbi.nlm.nih.gov/pubmed/34177493 Genome-Wide Association Study of Motor Coordination. Motor coordination 4,542 European ancestry children NA Illumina [4774020] (imputed) 7 motor function measurement http://www.ebi.ac.uk/efo/EFO_0010749 GCST012137 Genome-wide genotyping array 4542 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (XELOX) (Peripheral Neuropathy) 707 European ancestry individuals NA NR [4178855] (imputed) 0 peripheral neuropathy, chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0003100, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017191 Genome-wide genotyping array 707 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (XELOX,Cetuximab) (Peripheral Neuropathy) 348 European ancestry individuals NA NR [4176489] (imputed) 0 peripheral neuropathy, chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0003100, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017192 Genome-wide genotyping array 348 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX) (Peripheral Neuropathy) 385 European ancestry individuals NA NR [4176743] (imputed) 0 peripheral neuropathy, chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0003100, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017193 Genome-wide genotyping array 385 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX,Cetuximab) (Peripheral Neuropathy) 360 European ancestry individuals NA NR [4164603] (imputed) 0 peripheral neuropathy, chemotherapy-induced cytotoxicity measurement http://www.ebi.ac.uk/efo/EFO_0003100, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017194 Genome-wide genotyping array 360 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (XELOX) (Stomatitis) 707 European ancestry individuals NA NR [4167969] (imputed) 0 chemotherapy-induced cytotoxicity measurement, stomatitis http://www.ebi.ac.uk/efo/EFO_0010978, http://www.ebi.ac.uk/efo/EFO_0009688 GCST90017195 Genome-wide genotyping array 707 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (XELOX,Cetuximab) (Stomatitis) 348 European ancestry individuals NA NR [4161930] (imputed) 0 chemotherapy-induced cytotoxicity measurement, stomatitis http://www.ebi.ac.uk/efo/EFO_0010978, http://www.ebi.ac.uk/efo/EFO_0009688 GCST90017196 Genome-wide genotyping array 348 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX) (Stomatitis) 385 European ancestry individuals NA NR [4177511] (imputed) 0 chemotherapy-induced cytotoxicity measurement, stomatitis http://www.ebi.ac.uk/efo/EFO_0010978, http://www.ebi.ac.uk/efo/EFO_0009688 GCST90017197 Genome-wide genotyping array 385 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX,Cetuximab) (Stomatitis) 360 European ancestry individuals NA NR [4178858] (imputed) 0 chemotherapy-induced cytotoxicity measurement, stomatitis http://www.ebi.ac.uk/efo/EFO_0010978, http://www.ebi.ac.uk/efo/EFO_0009688 GCST90017198 Genome-wide genotyping array 360 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (XELOX) (Nausea) 707 European ancestry individuals NA NR [4178858] (imputed) 0 chemotherapy-induced cytotoxicity measurement, Nausea http://www.ebi.ac.uk/efo/EFO_0010978, http://purl.obolibrary.org/obo/HP_0002018 GCST90017199 Genome-wide genotyping array 707 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (XELOX,Cetuximab) (Nausea) 348 European ancestry individuals NA NR [4178713] (imputed) 0 chemotherapy-induced cytotoxicity measurement, Nausea http://www.ebi.ac.uk/efo/EFO_0010978, http://purl.obolibrary.org/obo/HP_0002018 GCST90017200 Genome-wide genotyping array 348 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX) (Nausea) 385 European ancestry individuals NA NR [4175233] (imputed) 0 chemotherapy-induced cytotoxicity measurement, Nausea http://www.ebi.ac.uk/efo/EFO_0010978, http://purl.obolibrary.org/obo/HP_0002018 GCST90017201 Genome-wide genotyping array 385 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX,Cetuximab) (Nausea) 360 European ancestry individuals NA NR [4176780] (imputed) 1 chemotherapy-induced cytotoxicity measurement, Nausea http://www.ebi.ac.uk/efo/EFO_0010978, http://purl.obolibrary.org/obo/HP_0002018 GCST90017202 Genome-wide genotyping array 360 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (XELOX) (Vomiting) 707 European ancestry individuals NA NR [4178857] (imputed) 0 Vomiting, chemotherapy-induced cytotoxicity measurement http://purl.obolibrary.org/obo/HP_0002013, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017203 Genome-wide genotyping array 707 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (XELOX,Cetuximab) (Vomiting) 348 European ancestry individuals NA NR [4171342] (imputed) 0 Vomiting, chemotherapy-induced cytotoxicity measurement http://purl.obolibrary.org/obo/HP_0002013, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017204 Genome-wide genotyping array 348 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX) (Vomiting) 385 European ancestry individuals NA NR [4150631] (imputed) 0 Vomiting, chemotherapy-induced cytotoxicity measurement http://purl.obolibrary.org/obo/HP_0002013, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017205 Genome-wide genotyping array 385 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX,Cetuximab) (Vomiting) 360 European ancestry individuals NA NR [4169348] (imputed) 0 Vomiting, chemotherapy-induced cytotoxicity measurement http://purl.obolibrary.org/obo/HP_0002013, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017206 Genome-wide genotyping array 360 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (XELOX) (Diarrhoea) 707 European ancestry individuals NA NR [4178858] (imputed) 0 Diarrhea, chemotherapy-induced cytotoxicity measurement http://purl.obolibrary.org/obo/HP_0002014, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017207 Genome-wide genotyping array 707 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (XELOX,Cetuximab) (Diarrhoea) 348 European ancestry individuals NA NR [4178858] (imputed) 1 Diarrhea, chemotherapy-induced cytotoxicity measurement http://purl.obolibrary.org/obo/HP_0002014, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017208 Genome-wide genotyping array 348 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX) (Diarrhoea) 385 European ancestry individuals NA NR [4178775] (imputed) 0 Diarrhea, chemotherapy-induced cytotoxicity measurement http://purl.obolibrary.org/obo/HP_0002014, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017209 Genome-wide genotyping array 385 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX,Cetuximab) (Diarrhoea) 360 European ancestry individuals NA NR [4178855] (imputed) 0 Diarrhea, chemotherapy-induced cytotoxicity measurement http://purl.obolibrary.org/obo/HP_0002014, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017210 Genome-wide genotyping array 360 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (XELOX) (Lethargy) 707 European ancestry individuals NA NR [4178858] (imputed) 1 sleepiness, chemotherapy-induced cytotoxicity measurement http://purl.obolibrary.org/obo/NCIT_C95746, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017211 Genome-wide genotyping array 707 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (XELOX,Cetuximab) (Lethargy) 348 European ancestry individuals NA NR [4178857] (imputed) 0 sleepiness, chemotherapy-induced cytotoxicity measurement http://purl.obolibrary.org/obo/NCIT_C95746, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017212 Genome-wide genotyping array 348 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX) (Lethargy) 385 European ancestry individuals NA NR [4178858] (imputed) 0 sleepiness, chemotherapy-induced cytotoxicity measurement http://purl.obolibrary.org/obo/NCIT_C95746, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017213 Genome-wide genotyping array 385 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (FOLFOX,Cetuximab) (Lethargy) 360 European ancestry individuals NA NR [4178858] (imputed) 0 sleepiness, chemotherapy-induced cytotoxicity measurement http://purl.obolibrary.org/obo/NCIT_C95746, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017214 Genome-wide genotyping array 360 2021-07-27 34270794 Watts K 2021-07-16 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34270794 Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer. Adverse response to chemotherapy in colorectal cancer (XELOX) (Neutropenia) 707 European ancestry individuals NA NR [4172253] (imputed) 0 neutropenia, chemotherapy-induced cytotoxicity measurement http://purl.obolibrary.org/obo/MONDO_0001475, http://www.ebi.ac.uk/efo/EFO_0010978 GCST90017215 Genome-wide genotyping array 707 2021-06-24 34062886 Nazarian A 2021-05-01 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/34062886 Genome-Wide Analysis of Sex Disparities in the Genetic Architecture of Lung and Colorectal Cancers. Lung cancer 237 European ancestry female cases, 220 European ancestry male cases, 8,354 European ancestry female controls, 6,278 European ancestry male controls NA NR [up to 1668434] (imputed) 12 lung cancer http://purl.obolibrary.org/obo/MONDO_0008903 GCST011974 Genome-wide genotyping array 15089 2021-06-24 34062886 Nazarian A 2021-05-01 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/34062886 Genome-Wide Analysis of Sex Disparities in the Genetic Architecture of Lung and Colorectal Cancers. Colorectal cancer 211 European ancestry female cases, 186 European ancestry male cases, 8,382 European ancestry female controls, 6,312 European ancestry male controls NA NR [up to 1668415] (imputed) 7 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST011973 Genome-wide genotyping array 15091 2021-06-30 34052317 Li M 2021-05-28 Genomics www.ncbi.nlm.nih.gov/pubmed/34052317 A next generation sequencing combined genome-wide association study identifies novel tuberculosis susceptibility loci in Chinese population. Tuberculosis 29 Chinese ancestry cases, 77 Chinese ancestry controls 569 Chinese ancestry cases, 534 Chinese ancestry controls Illumina [152523] 0 Tuberculosis http://www.orpha.net/ORDO/Orphanet_3389 GCST011980 Genome-wide genotyping array 106 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Coagulation factor Xa measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 coagulation factor measurement http://www.ebi.ac.uk/efo/EFO_0004634 GCST90019430 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Interleukin-2 receptor subunit alpha measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 interleukin-2 receptor subunit alpha measurement http://www.ebi.ac.uk/efo/EFO_0010587 GCST90019431 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Interleukin-7 receptor subunit alpha measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 interleukin 7 receptor subunit alpha measurement http://www.ebi.ac.uk/efo/EFO_0008190 GCST90019457 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Complement C2 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019433 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Prothrombin measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019459 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Interleukin-1 receptor antagonist protein measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 interleukin 1 receptor antagonist measurement http://www.ebi.ac.uk/efo/EFO_0004754 GCST90019460 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. GDP-fucose protein O-fucosyltransferase 1 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019461 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Antithrombin-III measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019436 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Coagulation factor XIII B chain measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 coagulation factor measurement http://www.ebi.ac.uk/efo/EFO_0004634 GCST90019463 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. von Willebrand factor A domain-containing protein 1 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 von Willebrand factor measurement http://www.ebi.ac.uk/efo/EFO_0004629 GCST90019464 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Protein FAM162A measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019465 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Plasminogen measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 plasma plasminogen measurement http://www.ebi.ac.uk/efo/EFO_0006309 GCST90019440 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. von Willebrand factor A domain-containing protein 2 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 von Willebrand factor measurement http://www.ebi.ac.uk/efo/EFO_0004629 GCST90019468 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Complement factor H measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019442 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. ERO1-like protein beta measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019471 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. KDEL motif-containing protein 2 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019472 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Sulfhydryl oxidase 2 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019473 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Complement C1s subcomponent measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 complement C1s subcomponent measurement http://www.ebi.ac.uk/efo/EFO_0008091 GCST90019474 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Endoplasmic reticulum lectin 1 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019475 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Monocyte differentiation antigen CD14 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019476 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Palmitoyl-protein thioesterase 1 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019477 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Neuronal pentraxin-1 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019478 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Lactadherin measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 lactadherin measurement http://www.ebi.ac.uk/efo/EFO_0008203 GCST90019448 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Gelsolin measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019449 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Inter-alpha-trypsin inhibitor heavy chain H4 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019450 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Coagulation factor IX measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 coagulation factor measurement http://www.ebi.ac.uk/efo/EFO_0004634 GCST90019451 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Coagulation Factor X measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 coagulation factor measurement http://www.ebi.ac.uk/efo/EFO_0004634 GCST90019452 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Coagulation Factor V measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 coagulation factor V measurement http://www.ebi.ac.uk/efo/EFO_0008087 GCST90019453 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. D-dimer measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019454 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. O-phosphoseryl-tRNA(Sec) selenium transferase measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019405 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Heme oxygenase 1 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019406 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Electron transfer flavoprotein subunit alpha, mitochondrial measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019407 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Catechol O-methyltransferase measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019408 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Amino-terminal enhancer of split measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019409 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Prostaglandin E synthase 2 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019410 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Serum amyloid A-2 protein measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019411 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Ras-related protein Rab-1A measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019412 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Protein Z-dependent protease inhibitor measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019385 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Coagulation Factor VIII measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 coagulation factor measurement http://www.ebi.ac.uk/efo/EFO_0004634 GCST90019386 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. AP-2 complex subunit alpha-2 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019387 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. NADPH--cytochrome P450 reductase measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 NADPH--cytochrome P450 reductase measurement http://www.ebi.ac.uk/efo/EFO_0008242 GCST90019418 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Immunoglobulin G measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019419 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Apolipoprotein A-I measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019420 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Rap1 GTPase-GDP dissociation stimulator 1 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019390 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Interleukin-1 receptor type 2 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019391 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Complement component C8 gamma chain measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019392 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Interleukin-17 receptor A measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 interleukin 17 receptor A measurement http://www.ebi.ac.uk/efo/EFO_0008175 GCST90019425 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Serum amyloid A-1 protein measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 serum amyloid A-1 protein measurement http://www.ebi.ac.uk/efo/EFO_0008282 GCST90019394 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Haptoglobin measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 haptoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004640 GCST90019428 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Alpha-galactosidase A measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019396 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Glutathione peroxidase 1 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019397 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Interleukin-6 receptor subunit alpha measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 interleukin 6 receptor subunit alpha measurement http://www.ebi.ac.uk/efo/EFO_0008187 GCST90019398 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Gelsolin measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019399 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Collagen alpha-1(VI) chain measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019400 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Ras-related protein Rab-2A measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019401 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Monocyte differentiation antigen CD14, soluble measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019402 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Coagulation factor XIII measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 coagulation factor measurement http://www.ebi.ac.uk/efo/EFO_0004634 GCST90019403 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Medium-chain specific acyl-CoA dehydrogenase, mitochondrial measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019404 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Fibrinogen gamma chain measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 fibrinogen measurement http://www.ebi.ac.uk/efo/EFO_0004623 GCST90019455 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Galectin-3-binding protein measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 galectin-3-binding protein measurement http://www.ebi.ac.uk/efo/EFO_0010241 GCST90019456 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Coagulation factor VII measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 coagulation factor measurement http://www.ebi.ac.uk/efo/EFO_0004634 GCST90019432 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Coagulation factor IXab measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 coagulation factor measurement http://www.ebi.ac.uk/efo/EFO_0004634 GCST90019458 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Insulin-degrading enzyme measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019434 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Complement C1r subcomponent measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 complement C1r subcomponent measurement http://www.ebi.ac.uk/efo/EFO_0008090 GCST90019435 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Procollagen galactosyltransferase 1 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019462 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Angiostatin measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 angiostatin measurement http://www.ebi.ac.uk/efo/EFO_0008024 GCST90019437 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Creatine kinase M-type:Creatine kinase B-type heterodimer measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019438 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Complement factor B measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 complement factor B measurement http://www.ebi.ac.uk/efo/EFO_0008096 GCST90019439 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019466 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. GrpE protein homolog 1, mitochondrial measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019467 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Thrombin measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019441 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Inter-alpha-trypsin inhibitor heavy chain H3 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019469 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Haptoglobin measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 haptoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004640 GCST90019470 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Serotransferrin measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019443 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Interleukin-1 receptor-like 1 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 interleukin 1 receptor-like 1 measurement http://www.ebi.ac.uk/efo/EFO_0008168 GCST90019444 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. dCTP pyrophosphatase 1 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019445 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. C-reactive protein measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST90019446 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Growth/differentiation factor 15 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019447 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Peptidyl-prolyl cis-trans isomerase FKBP7 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019479 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Scavenger receptor class A member 5 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019380 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Phospholipase D3 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019381 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019382 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019383 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. SPARC-related modular calcium-binding protein 1 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019384 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Coagulation Factor XI measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 coagulation factor measurement http://www.ebi.ac.uk/efo/EFO_0004634 GCST90019413 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Tissue-type plasminogen activator measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019414 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Complement component C8 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 complement component C8 measurement http://www.ebi.ac.uk/efo/EFO_0008094 GCST90019415 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Interleukin-6 receptor subunit beta measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 interleukin 6 receptor subunit beta measurement http://www.ebi.ac.uk/efo/EFO_0008188 GCST90019416 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Vitamin K-dependent protein S measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019417 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Interleukin-1 Receptor accessory protein measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 interleukin 1 Receptor accessory protein measurement http://www.ebi.ac.uk/efo/EFO_0008167 GCST90019388 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Plakophilin-2 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019389 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Fibrinogen measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 fibrinogen measurement http://www.ebi.ac.uk/efo/EFO_0004623 GCST90019421 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Plasminogen activator inhibitor 1 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 plasminogen activator inhibitor 1 measurement http://www.ebi.ac.uk/efo/EFO_0004792 GCST90019422 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Vitamin K-dependent protein C measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 vitamin K-dependent protein C measurement http://www.ebi.ac.uk/efo/EFO_0008318 GCST90019423 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Interleukin-1 receptor type 1 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019424 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Stromal cell-derived factor 2 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019393 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Interleukin-1 receptor-like 2 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 interleukin 1 receptor-like 2 measurement http://www.ebi.ac.uk/efo/EFO_0008169 GCST90019426 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. von Willebrand factor measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 von Willebrand factor measurement http://www.ebi.ac.uk/efo/EFO_0004629 GCST90019427 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Fibulin-5 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019395 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Lipopolysaccharide-binding protein measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019429 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Interleukin-2 receptor subunit beta measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019480 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Complement C1r subcomponent-like protein measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019481 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Gamma-glutamyl hydrolase measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019482 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Vesicular integral-membrane protein VIP36 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019483 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. Eukaryotic translation initiation factor 4E type 2 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST90019484 Genome-wide genotyping array 10708 2021-06-25 33328453 Pietzner M 2020-12-16 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33328453 Genetic architecture of host proteins involved in SARS-CoV-2 infection. MAP/microtubule affinity-regulating kinase 3 measurement 10,708 European ancestry individuals NA Affymetrix, Illumina [17652797] (imputed) 0 MAP kinase-activated protein kinase 3 measurement http://www.ebi.ac.uk/efo/EFO_0008226 GCST90019485 Genome-wide genotyping array 10708 2021-09-20 34454985 Sliz E 2021-08-26 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/34454985 Uniting biobank resources reveals novel genetic pathways modulating susceptibility for atopic dermatitis. Atopic dermatitis 22,474 European ancestry cases, 774,187 European ancestry controls NA Affymetrix, Illumina [16201029] (imputed) 30 atopic eczema http://www.ebi.ac.uk/efo/EFO_0000274 GCST90027161 Genome-wide genotyping array 796661 2021-10-01 34119372 Lord J 2021-05-04 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/34119372 A genome-wide association study of plasma phosphorylated tau181. Plasma p-tau181 levels 1,153 European ancestry individuals NA Illumina [5688385] (imputed) 2 p-tau measurement http://www.ebi.ac.uk/efo/EFO_0004763 GCST90027237 Genome-wide genotyping array 1153 2021-08-13 34319593 Li N 2021-07-28 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/34319593 Genetic variants of CYP4F12 gene are associated with glioma susceptibility. Glioma 485 Han Chinese ancestry cases, 485 Han Chinese ancestry controls NA Affymetrix [4635191] (imputed) 2 glioma http://www.ebi.ac.uk/efo/EFO_0005543 GCST90020047 Genome-wide genotyping array 970 2021-08-13 34302048 Qu HQ 2021-07-23 Commun Biol www.ncbi.nlm.nih.gov/pubmed/34302048 Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci. Type 1 diabetes with low genetic risk score 957 European ancestry cases, 12,323 European ancestry controls NA Illumina [104689647] (imputed) 149 type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001359 GCST90000181 Genome-wide genotyping array 13280 2021-08-13 34302048 Qu HQ 2021-07-23 Commun Biol www.ncbi.nlm.nih.gov/pubmed/34302048 Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci. Type 1 diabetes 6,599 European ancestry cases, 12,323 European ancestry controls NA Illumina [104689647] (imputed) 113 type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001359 GCST012179 Genome-wide genotyping array 18922 2021-06-09 34012061 Sipeky C 2021-05-19 Prostate Cancer Prostatic Dis www.ncbi.nlm.nih.gov/pubmed/34012061 Novel prostate cancer susceptibility gene SP6 predisposes patients to aggressive disease. Prostate cancer 2,738 Finnish ancestry cases, 2,400 Finnish ancestry controls NA Illumina [185478] 21 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST011829 Genome-wide genotyping array 5138 2021-06-17 34016946 Wu LS 2021-05-20 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/34016946 Genome-wide association study of early-onset bipolar I disorder in the Han Taiwanese population. Bipolar disorder (early vs late onset) 516 Han Taiwanese ancestry cases, 790 Han Taiwanese ancestry controls 153 Han Taiwanese ancestry cases, 320 Han Taiwanese ancestry controls Illumina [4750978] (imputed) 4 bipolar I disorder http://www.ebi.ac.uk/efo/EFO_0009963 GCST011908 Genome-wide genotyping array 1306 2021-07-27 34106200 Machipisa T 2021-06-09 JAMA Cardiol www.ncbi.nlm.nih.gov/pubmed/34106200 Association of Novel Locus With Rheumatic Heart Disease in Black African Individuals: Findings From the RHDGen Study. Rheumatic heart disease 601 European ancestry, South East Asian ancestry, South Asian ancestry, African ancestry and South African ancestry cases, 454 European ancestry, South East Asian ancestry, South Asian ancestry, African ancestry and South African ancestry controls NA Illumina [7605010] (imputed) 6 rheumatic heart disease http://www.ebi.ac.uk/efo/EFO_1001161 GCST012116 Genome-wide genotyping array 1055 2021-07-27 34106200 Machipisa T 2021-06-09 JAMA Cardiol www.ncbi.nlm.nih.gov/pubmed/34106200 Association of Novel Locus With Rheumatic Heart Disease in Black African Individuals: Findings From the RHDGen Study. Rheumatic heart disease 1,687 Sub-Saharan African ancestry and African ancestry cases, 1,492 Sub-Saharan African ancestry and African ancestry controls, 601 European ancestry, South East Asian ancestry, South Asian ancestry, African ancestry and South African ancestry cases, 454 European ancestry, South East Asian ancestry, South Asian ancestry, African ancestry and South African ancestry controls NA Illumina [7605010] (imputed) 6 rheumatic heart disease http://www.ebi.ac.uk/efo/EFO_1001161 GCST012115 Genome-wide genotyping array 4234 2021-07-27 34106200 Machipisa T 2021-06-09 JAMA Cardiol www.ncbi.nlm.nih.gov/pubmed/34106200 Association of Novel Locus With Rheumatic Heart Disease in Black African Individuals: Findings From the RHDGen Study. Rheumatic heart disease 1,687 Sub-Saharan African ancestry and African ancestry cases, 1,492 Sub-Saharan African ancestry and African ancestry controls NA Illumina [7605010] (imputed) 6 rheumatic heart disease http://www.ebi.ac.uk/efo/EFO_1001161 GCST012117 Genome-wide genotyping array 3179 2021-06-21 34011352 Schwarm C 2021-05-19 Orphanet J Rare Dis www.ncbi.nlm.nih.gov/pubmed/34011352 Identification of two novel bullous pemphigoid- associated alleles, HLA-DQA1*05:05 and -DRB1*07:01, in Germans. Bullous pemphigoid 438 German cases, 417 German controls NA Affymetrix [up to 386296] (imputed) 13 bullous pemphigoid http://www.ebi.ac.uk/efo/EFO_0007187 GCST011940 Genome-wide genotyping array 855 2021-10-04 34022066 Kim KW 2021-05-22 Allergy www.ncbi.nlm.nih.gov/pubmed/34022066 Genome-wide association study identifies TNFSF15associated with childhood asthma. Asthma (childhood onset) 741 Korean ancestry cases, 1,140 Korean ancestry controls NA Affymetrix, Illumina [4559629] (imputed) 3 childhood onset asthma http://www.ebi.ac.uk/efo/EFO_0004591 GCST012429 Genome-wide genotyping array 1881 2021-09-24 33349686 Wendt FR 2020-12-21 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/33349686 Multivariate genome-wide analysis of education, socioeconomic status and brain phenome. Neuroticism conditioned on cognitive performance (multi-trait conditioning and joint analysis) 170,911 European ancestry individuals NA NR [NR] 93 neuroticism measurement http://www.ebi.ac.uk/efo/EFO_0007660 GCST90027239 Genome-wide genotyping array 170911 2021-09-24 33349686 Wendt FR 2020-12-21 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/33349686 Multivariate genome-wide analysis of education, socioeconomic status and brain phenome. Neuroticism conditioned on Townsend deprivation index (multi-trait conditioning and joint analysis) 170,911 European ancestry individuals NA NR [NR] 100 neuroticism measurement http://www.ebi.ac.uk/efo/EFO_0007660 GCST90027240 Genome-wide genotyping array 170911 2021-09-24 33349686 Wendt FR 2020-12-21 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/33349686 Multivariate genome-wide analysis of education, socioeconomic status and brain phenome. Neuroticism conditioned on educational attainment (multi-trait conditioning and joint analysis) 170,911 European ancestry individuals NA NR [NR] 81 neuroticism measurement http://www.ebi.ac.uk/efo/EFO_0007660 GCST90027241 Genome-wide genotyping array 170911 2021-09-24 33349686 Wendt FR 2020-12-21 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/33349686 Multivariate genome-wide analysis of education, socioeconomic status and brain phenome. Neuroticism conditioned on highest math class (multi-trait conditioning and joint analysis) 170,911 European ancestry individuals NA NR [NR] 82 neuroticism measurement http://www.ebi.ac.uk/efo/EFO_0007660 GCST90027242 Genome-wide genotyping array 170911 2021-09-24 33349686 Wendt FR 2020-12-21 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/33349686 Multivariate genome-wide analysis of education, socioeconomic status and brain phenome. Neuroticism conditioned on average household income before tax (multi-trait conditioning and joint analysis) 170,911 European ancestry individuals NA NR [NR] 59 neuroticism measurement http://www.ebi.ac.uk/efo/EFO_0007660 GCST90027243 Genome-wide genotyping array 170911 2021-09-24 33349686 Wendt FR 2020-12-21 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/33349686 Multivariate genome-wide analysis of education, socioeconomic status and brain phenome. Neuroticism conditioned on self-rated math ability (multi-trait conditioning and joint analysis) 170,911 European ancestry individuals NA NR [NR] 70 neuroticism measurement http://www.ebi.ac.uk/efo/EFO_0007660 GCST90027244 Genome-wide genotyping array 170911 2021-09-24 33349686 Wendt FR 2020-12-21 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/33349686 Multivariate genome-wide analysis of education, socioeconomic status and brain phenome. Subjective wellbeing conditioned on cognitive performance (multi-trait conditioning and joint analysis) 298,420 European ancestry individuals NA NR [NR] 2 wellbeing measurement http://www.ebi.ac.uk/efo/EFO_0007869 GCST90032159 Genome-wide genotyping array 298420 2021-09-24 33349686 Wendt FR 2020-12-21 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/33349686 Multivariate genome-wide analysis of education, socioeconomic status and brain phenome. Subjective wellbeing conditioned on Townsend deprivation index (multi-trait conditioning and joint analysis) 298,420 European ancestry individuals NA NR [NR] 3 wellbeing measurement http://www.ebi.ac.uk/efo/EFO_0007869 GCST90032160 Genome-wide genotyping array 298420 2021-09-24 33349686 Wendt FR 2020-12-21 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/33349686 Multivariate genome-wide analysis of education, socioeconomic status and brain phenome. Subjective wellbeing conditioned on educational attainment (multi-trait conditioning and joint analysis) 298,420 European ancestry individuals NA NR [NR] 2 wellbeing measurement http://www.ebi.ac.uk/efo/EFO_0007869 GCST90032161 Genome-wide genotyping array 298420 2021-09-24 33349686 Wendt FR 2020-12-21 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/33349686 Multivariate genome-wide analysis of education, socioeconomic status and brain phenome. Subjective wellbeing conditioned on highest math class (multi-trait conditioning and joint analysis) 298,420 European ancestry individuals NA NR [NR] 2 wellbeing measurement http://www.ebi.ac.uk/efo/EFO_0007869 GCST90032162 Genome-wide genotyping array 298420 2021-09-24 33349686 Wendt FR 2020-12-21 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/33349686 Multivariate genome-wide analysis of education, socioeconomic status and brain phenome. Subjective wellbeing conditioned on average household income before tax (multi-trait conditioning and joint analysis) 298,420 European ancestry individuals NA NR [NR] 3 wellbeing measurement http://www.ebi.ac.uk/efo/EFO_0007869 GCST90032163 Genome-wide genotyping array 298420 2021-09-24 33349686 Wendt FR 2020-12-21 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/33349686 Multivariate genome-wide analysis of education, socioeconomic status and brain phenome. Subjective wellbeing conditioned on self-rated math ability (multi-trait conditioning and joint analysis) 298,420 European ancestry individuals NA NR [NR] 2 wellbeing measurement http://www.ebi.ac.uk/efo/EFO_0007869 GCST90032164 Genome-wide genotyping array 298420 2021-07-27 34014839 Page GP 2021-05-20 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/34014839 Multi-ancestry genome-wide association study identifies 27 loci associated with measures of hemolysis following blood storage. hemolysis of donated blood (osmotic) Up to 7,586 non-Hispanic White ancestry individuals, Up to 1,049 East Asian ancestry individuals, Up to 257 South Asian ancestry individuals, Up to 1,046 African Americans individuals, Up to 456 Mexican and Central American Hispanics individuals, Up to 489 Caribbean Island Hispanics, Up to 1,336 individuals NA NR [14100000] (imputed) 14 hemolysis http://www.ebi.ac.uk/efo/EFO_0009473 GCST012135 Genome-wide genotyping array 12219 2021-07-27 34014839 Page GP 2021-05-20 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/34014839 Multi-ancestry genome-wide association study identifies 27 loci associated with measures of hemolysis following blood storage. hemolysis of donated blood (oxidative) Up to 7,586 non-Hispanic White ancestry individuals, Up to 1,049 East Asian ancestry individuals, Up to 257 South Asian ancestry individuals, Up to 1,046 African Americans individuals, Up to 456 Mexican and Central American Hispanics individuals, Up to 489 Caribbean Island Hispanics, Up to 1,336 individuals NA NR [14100000] (imputed) 4 hemolysis http://www.ebi.ac.uk/efo/EFO_0009473 GCST012134 Genome-wide genotyping array 12219 2021-07-27 34014839 Page GP 2021-05-20 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/34014839 Multi-ancestry genome-wide association study identifies 27 loci associated with measures of hemolysis following blood storage. hemolysis of donated blood (cold-storage) Up to 7,586 non-Hispanic White ancestry individuals, Up to 1,049 East Asian ancestry individuals, Up to 257 South Asian ancestry individuals, Up to 1,046 African Americans individuals, Up to 456 Mexican and Central American Hispanics individuals, Up to 489 Caribbean Island Hispanics, Up to 1,336 individuals NA NR [14100000] (imputed) 2 hemolysis http://www.ebi.ac.uk/efo/EFO_0009473 GCST012133 Genome-wide genotyping array 12219 2021-07-27 34014839 Page GP 2021-05-20 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/34014839 Multi-ancestry genome-wide association study identifies 27 loci associated with measures of hemolysis following blood storage. hemolysis of donated blood (osmotic) Up to 456 Mexican and Central American Hispanics individuals, Up to 489 Caribbean Island Hispanics individuals NA NR [14100000] (imputed) 3 hemolysis http://www.ebi.ac.uk/efo/EFO_0009473 GCST012132 Genome-wide genotyping array 945 2021-07-27 34014839 Page GP 2021-05-20 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/34014839 Multi-ancestry genome-wide association study identifies 27 loci associated with measures of hemolysis following blood storage. hemolysis of donated blood (osmotic) Up to 1,049 East Asian ancestry individuals NA NR [14100000] (imputed) 2 hemolysis http://www.ebi.ac.uk/efo/EFO_0009473 GCST012131 Genome-wide genotyping array 1049 2021-07-27 34014839 Page GP 2021-05-20 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/34014839 Multi-ancestry genome-wide association study identifies 27 loci associated with measures of hemolysis following blood storage. hemolysis of donated blood (osmotic) Up to 1,046 African Americans individuals NA NR [14100000] (imputed) 3 hemolysis http://www.ebi.ac.uk/efo/EFO_0009473 GCST012130 Genome-wide genotyping array 1046 2021-07-27 34014839 Page GP 2021-05-20 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/34014839 Multi-ancestry genome-wide association study identifies 27 loci associated with measures of hemolysis following blood storage. hemolysis of donated blood (oxidative) Up to 1,046 African Americans individuals NA NR [14100000] (imputed) 1 hemolysis http://www.ebi.ac.uk/efo/EFO_0009473 GCST012129 Genome-wide genotyping array 1046 2021-07-27 34014839 Page GP 2021-05-20 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/34014839 Multi-ancestry genome-wide association study identifies 27 loci associated with measures of hemolysis following blood storage. hemolysis of donated blood (cold-storage) Up to 7,586 non-Hispanic White ancestry individuals NA NR [14100000] (imputed) 1 hemolysis http://www.ebi.ac.uk/efo/EFO_0009473 GCST012128 Genome-wide genotyping array 7586 2021-07-27 34014839 Page GP 2021-05-20 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/34014839 Multi-ancestry genome-wide association study identifies 27 loci associated with measures of hemolysis following blood storage. hemolysis of donated blood (oxidative) Up to 7,586 non-Hispanic White ancestry individuals NA NR [14100000] (imputed) 1 hemolysis http://www.ebi.ac.uk/efo/EFO_0009473 GCST012127 Genome-wide genotyping array 7586 2021-07-27 34014839 Page GP 2021-05-20 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/34014839 Multi-ancestry genome-wide association study identifies 27 loci associated with measures of hemolysis following blood storage. hemolysis of donated blood (osmotic) Up to 7,586 non-Hispanic White ancestry individuals NA NR [14100000] (imputed) 14 hemolysis http://www.ebi.ac.uk/efo/EFO_0009473 GCST012126 Genome-wide genotyping array 7586 2021-07-27 33455090 Bing N 2021-01-17 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/33455090 Contribution of a European-Prevalent Variant near CD83 and an East Asian-Prevalent Variant near IL17RB to Herpes Zoster Risk in Tofacitinib Treatment: Results of Genome-Wide Association Study Meta-Analyses. Response to tofacitinib treatment in rheumatoid arthritis (herpes zoster)(time to event) 165 European ancestry cases, 2,023 European ancestry controls, 56 East Asian ancestry cases, 237 East Asian ancestry controls, 23 Hispanic cases, 399 Hispanic controls NA Illumina [up to 8000000] (imputed) 4 Herpes Zoster, response to tofacitinib http://www.ebi.ac.uk/efo/EFO_0006510, http://www.ebi.ac.uk/efo/EFO_0600024 GCST012086 Genome-wide genotyping array 2903 2021-07-27 33455090 Bing N 2021-01-17 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/33455090 Contribution of a European-Prevalent Variant near CD83 and an East Asian-Prevalent Variant near IL17RB to Herpes Zoster Risk in Tofacitinib Treatment: Results of Genome-Wide Association Study Meta-Analyses. Response to tofacitinib treatment in psoriasis (herpes zoster)(time to event) 56 European ancestry cases, 1,543 European ancestry controls, 10 East Asian ancestry cases, 80 East Asian ancestry controls, 4 Hispanic cases, 245 Hispanic controls NA Illumina [up to 8000000] (imputed) 4 Herpes Zoster, response to tofacitinib http://www.ebi.ac.uk/efo/EFO_0006510, http://www.ebi.ac.uk/efo/EFO_0600024 GCST012085 Genome-wide genotyping array 1938 2021-07-27 33455090 Bing N 2021-01-17 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/33455090 Contribution of a European-Prevalent Variant near CD83 and an East Asian-Prevalent Variant near IL17RB to Herpes Zoster Risk in Tofacitinib Treatment: Results of Genome-Wide Association Study Meta-Analyses. Response to tofacitinib treatment in rheumatoid arthritis (herpes zoster) 165 European ancestry cases, 2,023 European ancestry controls, 56 East Asian ancestry cases, 237 East Asian ancestry controls, 23 Hispanic cases, 399 Hispanic controls NA Illumina [up to 8000000] (imputed) 4 Herpes Zoster, response to tofacitinib http://www.ebi.ac.uk/efo/EFO_0006510, http://www.ebi.ac.uk/efo/EFO_0600024 GCST012084 Genome-wide genotyping array 2903 2021-07-27 33455090 Bing N 2021-01-17 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/33455090 Contribution of a European-Prevalent Variant near CD83 and an East Asian-Prevalent Variant near IL17RB to Herpes Zoster Risk in Tofacitinib Treatment: Results of Genome-Wide Association Study Meta-Analyses. Response to tofacitinib treatment in psoriasis (herpes zoster) 56 European ancestry cases, 1,543 European ancestry controls, 10 East Asian ancestry cases, 80 East Asian ancestry controls, 4 Hispanic cases, 245 Hispanic controls NA Illumina [up to 8000000] (imputed) 3 Herpes Zoster, response to tofacitinib http://www.ebi.ac.uk/efo/EFO_0006510, http://www.ebi.ac.uk/efo/EFO_0600024 GCST012083 Genome-wide genotyping array 1938 2021-07-27 33455090 Bing N 2021-01-17 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/33455090 Contribution of a European-Prevalent Variant near CD83 and an East Asian-Prevalent Variant near IL17RB to Herpes Zoster Risk in Tofacitinib Treatment: Results of Genome-Wide Association Study Meta-Analyses. Response to tofacitinib treatment (herpes zoster)(time to event) 165 European ancestry rheumatoid arthritis cases, 56 East Asian ancestry rheumatoid arthritis cases, 23 Hispanic rheumatoid arthritis cases, 56 European ancestry psoriasis cases, 10 East Asian ancestry psoriasis cases, 4 Hispanic psoriasis cases, 3,566 European ancestry controls, 317 East Asian ancestry controls, 644 Hispanic controls NA Illumina [up to 8000000] (imputed) 5 Herpes Zoster, response to tofacitinib http://www.ebi.ac.uk/efo/EFO_0006510, http://www.ebi.ac.uk/efo/EFO_0600024 GCST012082 Genome-wide genotyping array 4841 2021-07-27 33455090 Bing N 2021-01-17 Arthritis Rheumatol www.ncbi.nlm.nih.gov/pubmed/33455090 Contribution of a European-Prevalent Variant near CD83 and an East Asian-Prevalent Variant near IL17RB to Herpes Zoster Risk in Tofacitinib Treatment: Results of Genome-Wide Association Study Meta-Analyses. Response to tofacitinib treatment (herpes zoster) 165 European ancestry rheumatoid arthritis cases, 56 East Asian ancestry rheumatoid arthritis cases, 23 Hispanic rheumatoid arthritis cases, 56 European ancestry psoriasis cases, 10 East Asian ancestry psoriasis cases, 4 Hispanic psoriasis cases, 3,566 European ancestry controls, 317 East Asian ancestry controls, 644 Hispanic controls NA Illumina [up to 8000000] (imputed) 5 Herpes Zoster, response to tofacitinib http://www.ebi.ac.uk/efo/EFO_0006510, http://www.ebi.ac.uk/efo/EFO_0600024 GCST012081 Genome-wide genotyping array 4841 2021-07-07 34006833 Elvsashagen T 2021-05-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/34006833 The genetic architecture of the human thalamus and its overlap with ten common brain disorders. Thalamus volume 30,114 white British ancestry individuals NA Affymetrix [8165723] (imputed) 7 thalamus volume http://www.ebi.ac.uk/efo/EFO_0006935 GCST012009 Genome-wide genotyping array 30114 2021-07-07 34006833 Elvsashagen T 2021-05-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/34006833 The genetic architecture of the human thalamus and its overlap with ten common brain disorders. Anterior thalamic nuclei volume 30,114 white British ancestry individuals NA Affymetrix [8165723] (imputed) 3 thalamus volume http://www.ebi.ac.uk/efo/EFO_0006935 GCST012005 Genome-wide genotyping array 30114 2021-07-07 34006833 Elvsashagen T 2021-05-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/34006833 The genetic architecture of the human thalamus and its overlap with ten common brain disorders. Lateral thalamic nuclei volume 30,114 white British ancestry individuals NA Affymetrix [8165723] (imputed) 11 thalamus volume http://www.ebi.ac.uk/efo/EFO_0006935 GCST012008 Genome-wide genotyping array 30114 2021-07-07 34006833 Elvsashagen T 2021-05-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/34006833 The genetic architecture of the human thalamus and its overlap with ten common brain disorders. Ventral thalamic nuclei volume 30,114 white British ancestry individuals NA Affymetrix [8165723] (imputed) 5 thalamus volume http://www.ebi.ac.uk/efo/EFO_0006935 GCST012011 Genome-wide genotyping array 30114 2021-07-07 34006833 Elvsashagen T 2021-05-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/34006833 The genetic architecture of the human thalamus and its overlap with ten common brain disorders. Intralaminar thalamic nuclei volume 30,114 white British ancestry individuals NA Affymetrix [8165723] (imputed) 12 thalamus volume http://www.ebi.ac.uk/efo/EFO_0006935 GCST012006 Genome-wide genotyping array 30114 2021-07-07 34006833 Elvsashagen T 2021-05-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/34006833 The genetic architecture of the human thalamus and its overlap with ten common brain disorders. Medial thalamic nuclei volume 30,114 white British ancestry individuals NA Affymetrix [8165723] (imputed) 6 thalamus volume http://www.ebi.ac.uk/efo/EFO_0006935 GCST012010 Genome-wide genotyping array 30114 2021-07-07 34006833 Elvsashagen T 2021-05-18 Nat Commun www.ncbi.nlm.nih.gov/pubmed/34006833 The genetic architecture of the human thalamus and its overlap with ten common brain disorders. Posterior thalamic nuclei volume 30,114 white British ancestry individuals NA Affymetrix [8165723] (imputed) 6 thalamus volume http://www.ebi.ac.uk/efo/EFO_0006935 GCST012004 Genome-wide genotyping array 30114 2021-07-07 34035401 Dube MP 2021-05-25 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34035401 Genetics of symptom remission in outpatients with COVID-19. Symptoms in placebo-treated COVID-19 outpatients at risk of severe disease (time to remission) 851 European ancestry individuals NA Illumina [6392715] (imputed) 2 time to remission of COVID-19 symptoms, COVID-19, response to placebo http://www.ebi.ac.uk/efo/EFO_0600020, http://purl.obolibrary.org/obo/MONDO_0100096, http://www.ebi.ac.uk/efo/EFO_0008344 GCST012001 Genome-wide genotyping array 851 2021-07-07 34035401 Dube MP 2021-05-25 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34035401 Genetics of symptom remission in outpatients with COVID-19. COVID-19 (hospitalized vs not hospitalized) 58 European ancestry cases, 1,797 European ancestry controls NA Illumina [6393360] (imputed) 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST012000 Genome-wide genotyping array 1855 2021-07-07 34035401 Dube MP 2021-05-25 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34035401 Genetics of symptom remission in outpatients with COVID-19. Symptoms in COVID-19 outpatients at risk of severe disease (time to remission) 1,723 European ancestry individuals NA Illumina [6392715] (imputed) 1 time to remission of COVID-19 symptoms, COVID-19 http://www.ebi.ac.uk/efo/EFO_0600020, http://purl.obolibrary.org/obo/MONDO_0100096 GCST012002 Genome-wide genotyping array 1723 2021-06-08 34050153 Laabs BH 2021-05-28 Nat Commun www.ncbi.nlm.nih.gov/pubmed/34050153 Identifying genetic modifiers of age-associated penetrance in X-linked dystonia-parkinsonism. X-linked dystonia-parkinsonism 353 Filipino ancestry individuals NA Illumina [4990999] (imputed) 0 X-linked dystonia-parkinsonism http://www.orpha.net/ORDO/Orphanet_53351 GCST90014263 Genome-wide genotyping array 353 2021-06-17 31784582 Chittoor G 2019-11-29 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31784582 Fine mapping and identification of serum urate loci in American Indians: The Strong Heart Family Study. Serum urate levels 2,000 American Indian individuals NA Illumina [162718] 2 urate measurement http://www.ebi.ac.uk/efo/EFO_0004531 GCST011923 Targeted genotyping array [Metabochip] 2000 2021-06-17 33955455 Beck JJ 2021-05-06 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33955455 Genetic Meta-Analysis of Twin Birth Weight Shows High Genetic Correlation with Singleton Birth Weight. Birth weight 42,212 European ancestry individuals NA Affymetrix, Illumina [7692335] (imputed) 2 birth weight http://www.ebi.ac.uk/efo/EFO_0004344 GCST90000030 Genome-wide genotyping array 42212 2021-08-13 34319380 Gaitanidis A 2021-07-28 JAMA Surg www.ncbi.nlm.nih.gov/pubmed/34319380 Association Between NEDD4L Variation and the Genetic Risk of Acute Appendicitis: A Multi-institutional Genome-Wide Association Study. Acute appendicitis 1,743 European or unknown ancestry cases, 27,963 European or unknown ancestry controls NA Illumina [5676600] (imputed) 1 appendicitis http://www.ebi.ac.uk/efo/EFO_0007149 GCST90013428 Genome-wide genotyping array 29706 2021-10-20 34112972 DeMichele-Sweet MAA 2021-06-10 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34112972 Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease. Psychosis in Alzheimer's disease 4,551 European ancestry cases, 5,796 European ancestry controls, 894 African American or unknown ancestry cases, 1,076 African American or unknown ancestry controls NA Illumina [7105229] (imputed) 31 psychotic symptoms http://www.ebi.ac.uk/efo/EFO_0005940 GCST90020050 Genome-wide genotyping array 12317 2021-07-29 34247186 Wendel B 2021-07-10 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/34247186 A genome-wide association study of the longitudinal course of executive functions. Executive function (trail making test B) x time interaction 1,272 European ancestry individuals NA Illumina [8241560] (imputed) 0 executive function measurement http://www.ebi.ac.uk/efo/EFO_0009332 GCST90020165 Genome-wide genotyping array 1272 2021-07-29 34247186 Wendel B 2021-07-10 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/34247186 A genome-wide association study of the longitudinal course of executive functions. Executive function (trail making test B) 1,272 European ancestry individuals NA Illumina [8235300] (imputed) 0 executive function measurement http://www.ebi.ac.uk/efo/EFO_0009332 GCST90020166 Genome-wide genotyping array 1272 2021-07-29 34247186 Wendel B 2021-07-10 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/34247186 A genome-wide association study of the longitudinal course of executive functions. Executive function (verbal digit span backwards test) x time interaction 1,297 European ancestry individuals NA Illumina [8241300] (imputed) 0 executive function measurement http://www.ebi.ac.uk/efo/EFO_0009332 GCST90020167 Genome-wide genotyping array 1297 2021-07-29 34247186 Wendel B 2021-07-10 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/34247186 A genome-wide association study of the longitudinal course of executive functions. Executive function (verbal digit span backwards test) 1,297 European ancestry individuals NA Illumina [8241300] (imputed) 0 executive function measurement http://www.ebi.ac.uk/efo/EFO_0009332 GCST90020168 Genome-wide genotyping array 1297 2021-08-23 33640202 Kim BH 2021-02-03 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/33640202 Genome-wide association study identifies susceptibility loci of brain atrophy to NFIA and ST18 in Alzheimer's disease. Left inferior frontal gyrus (orbital part) cortical thickness 919 European ancestry individuals 629 individuals Illumina [3041429] (imputed) 1 cortical thickness http://www.ebi.ac.uk/efo/EFO_0004840 GCST90025855 Genome-wide genotyping array 919 2021-08-23 33640202 Kim BH 2021-02-03 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/33640202 Genome-wide association study identifies susceptibility loci of brain atrophy to NFIA and ST18 in Alzheimer's disease. Left parahippocampal gyrus cortical thickness 919 European ancestry individuals 629 individuals Illumina [3041429] (imputed) 1 cortical thickness http://www.ebi.ac.uk/efo/EFO_0004840 GCST90025856 Genome-wide genotyping array 919 2021-10-22 34216462 Pistoni L 2021-07-03 Carcinogenesis www.ncbi.nlm.nih.gov/pubmed/34216462 Associations between pancreatic expression quantitative traits and risk of pancreatic ductal adenocarcinoma. Pancreatic ductal adenocarcinoma 7,207 European ancestry cases, 7,062 European ancestry controls 2,039 Japanese ancestry cases, 32,592 Japanese ancestry controls, 4,467 cases, 4,130 controls Illumina [7509345] (imputed) 2 pancreatic ductal adenocarcinoma http://www.ebi.ac.uk/efo/EFO_0002517 GCST90026648 Genome-wide genotyping array 14269 2021-10-08 34002096 Mullins N 2021-05-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34002096 Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Bipolar disorder 41,917 European ancestry cases, 371,549 European ancestry controls NA Affymetrix, Illumina [7549318] (imputed) 64 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST012465 Genome-wide genotyping array 413466 2021-10-08 34002096 Mullins N 2021-05-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34002096 Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Bipolar I disorder 25,060 European ancestry cases, 449,978 European ancestry controls NA Affymetrix, Illumina [7549318] (imputed) 44 bipolar I disorder http://www.ebi.ac.uk/efo/EFO_0009963 GCST012464 Genome-wide genotyping array 475038 2021-10-08 34002096 Mullins N 2021-05-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34002096 Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Bipolar II disorder 6,781 European ancestry cases, 364,075 European ancestry controls NA Affymetrix, Illumina [7549318] (imputed) 1 bipolar II disorder http://www.ebi.ac.uk/efo/EFO_0009964 GCST012463 Genome-wide genotyping array 370856 2021-10-05 34025683 Kanoni S 2021-05-07 Front Immunol www.ncbi.nlm.nih.gov/pubmed/34025683 Nutrigenetic Interactions Might Modulate the Antioxidant and Anti-Inflammatory Status in Mastiha-Supplemented Patients With NAFLD. Hemoglobin levels in non-alcoholic fatty liver disease x mastiha supplementation interaction 35 European or unknown ancestry mastiha exposed individuals, 52 European or unknown ancestry unexposed individuals NA Illumina [10307610] (imputed) 2 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST012440 Genome-wide genotyping array 87 2021-10-05 34025683 Kanoni S 2021-05-07 Front Immunol www.ncbi.nlm.nih.gov/pubmed/34025683 Nutrigenetic Interactions Might Modulate the Antioxidant and Anti-Inflammatory Status in Mastiha-Supplemented Patients With NAFLD. Total antioxidant status in non-alcoholic fatty liver disease x mastiha supplementation interaction 35 European or unknown ancestry mastiha exposed individuals, 52 European or unknown ancestry unexposed individuals NA Illumina [10307610] (imputed) 1 antioxidant measurement http://www.ebi.ac.uk/efo/EFO_0005119 GCST012439 Genome-wide genotyping array 87 2021-10-05 34025683 Kanoni S 2021-05-07 Front Immunol www.ncbi.nlm.nih.gov/pubmed/34025683 Nutrigenetic Interactions Might Modulate the Antioxidant and Anti-Inflammatory Status in Mastiha-Supplemented Patients With NAFLD. Interleukin-6 levels in non-alcoholic fatty liver disease x mastiha supplementation interaction 35 European or unknown ancestry mastiha exposed individuals, 52 European or unknown ancestry unexposed individuals NA Illumina [10307610] (imputed) 2 interleukin-6 measurement http://www.ebi.ac.uk/efo/EFO_0004810 GCST012438 Genome-wide genotyping array 87 2021-10-05 34025683 Kanoni S 2021-05-07 Front Immunol www.ncbi.nlm.nih.gov/pubmed/34025683 Nutrigenetic Interactions Might Modulate the Antioxidant and Anti-Inflammatory Status in Mastiha-Supplemented Patients With NAFLD. Interleukin-6 gene expression levels in non-alcoholic fatty liver disease x mastiha supplementation interaction 35 European or unknown ancestry mastiha exposed individuals, 52 European or unknown ancestry unexposed individuals NA Illumina [10307610] (imputed) 1 NA NA GCST012437 Genome-wide genotyping array 87 2021-10-05 34025683 Kanoni S 2021-05-07 Front Immunol www.ncbi.nlm.nih.gov/pubmed/34025683 Nutrigenetic Interactions Might Modulate the Antioxidant and Anti-Inflammatory Status in Mastiha-Supplemented Patients With NAFLD. TNF-alpha gene expression levels in non-alcoholic fatty liver disease x mastiha supplementation interaction 35 European or unknown ancestry mastiha exposed individuals, 52 European or unknown ancestry unexposed individuals NA Illumina [10307610] (imputed) 2 NA NA GCST012436 Genome-wide genotyping array 87 2021-10-05 34025683 Kanoni S 2021-05-07 Front Immunol www.ncbi.nlm.nih.gov/pubmed/34025683 Nutrigenetic Interactions Might Modulate the Antioxidant and Anti-Inflammatory Status in Mastiha-Supplemented Patients With NAFLD. Interleukin-10 levels in non-alcoholic fatty liver disease x mastiha supplementation interaction 35 European or unknown ancestry mastiha exposed individuals, 51 European or unknown ancestry unexposed individuals NA Illumina [10307610] (imputed) 2 interleukin 10 measurement http://www.ebi.ac.uk/efo/EFO_0004750 GCST012435 Genome-wide genotyping array 86 2021-10-05 34025683 Kanoni S 2021-05-07 Front Immunol www.ncbi.nlm.nih.gov/pubmed/34025683 Nutrigenetic Interactions Might Modulate the Antioxidant and Anti-Inflammatory Status in Mastiha-Supplemented Patients With NAFLD. Glutathione peroxidase in non-alcoholic fatty liver disease x mastiha supplementation interaction 35 European or unknown ancestry mastiha exposed individuals, 52 European or unknown ancestry unexposed individuals NA Illumina [10307610] (imputed) 2 NA NA GCST012441 Genome-wide genotyping array 87 2021-06-03 33009551 Zhang J 2020-10-03 Cereb Cortex www.ncbi.nlm.nih.gov/pubmed/33009551 Genome-Wide Association Analysis of Neonatal White Matter Microstructure. Neonatal white matter microstructure 471 European, Black, Asian, Native American or unknown ancestry individuals NA Affymetrix [NR] (imputed) 15 white matter microstructure measurement http://www.ebi.ac.uk/efo/EFO_0005674 GCST011780 Genome-wide genotyping array 471 2021-09-09 34159637 Otomo N 2021-06-22 J Bone Miner Res www.ncbi.nlm.nih.gov/pubmed/34159637 Polygenic Risk Score of Adolescent Idiopathic Scoliosis for Potential Clinical Use. Adolescent idiopathic scoliosis (Cobb angle) 4,465 Japanese ancestry individuals NA NR [NR] 0 adolescent idiopathic scoliosis http://www.ebi.ac.uk/efo/EFO_0005423 GCST012369 Genome-wide genotyping array 4465 2021-10-20 34076728 Zhang YM 2021-06-02 Mol Genet Genomics www.ncbi.nlm.nih.gov/pubmed/34076728 Shared genetic study gives insights into the shared and distinct pathogenic immunity components of IgA nephropathy and SLE. IgA nephropathy 1,180 East Asian ancestry cases, 899 East Asian ancestry controls NA Illumina [NR] (imputed) 7 IGA glomerulonephritis http://www.ebi.ac.uk/efo/EFO_0004194 GCST90020041 Genome-wide genotyping array 2079 2021-10-20 34076728 Zhang YM 2021-06-02 Mol Genet Genomics www.ncbi.nlm.nih.gov/pubmed/34076728 Shared genetic study gives insights into the shared and distinct pathogenic immunity components of IgA nephropathy and SLE. Systemic lupus erythematosus 1,639 East Asian ancestry cases, 2,410 East Asian ancestry controls NA Illumina [NR] (imputed) 39 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST90020042 Genome-wide genotyping array 4049 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Depression 65,075 European ancestry cases, 232,552 European ancestry controls NA NR [1198241] (imputed) 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90014436 Genome-wide genotyping array 297627 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Depression 14,625 European ancestry cases, 232,552 European ancestry controls NA NR [1198241] (imputed) 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90014437 Genome-wide genotyping array 247177 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Ankylosing spondylitis 1,344 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 ankylosing spondylitis http://www.ebi.ac.uk/efo/EFO_0003898 GCST90014438 Genome-wide genotyping array 325418 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Ankylosing spondylitis 413 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 ankylosing spondylitis http://www.ebi.ac.uk/efo/EFO_0003898 GCST90014439 Genome-wide genotyping array 324487 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Autoimmune thyroid disease 859 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 autoimmune thyroid disease http://www.ebi.ac.uk/efo/EFO_0006812 GCST90014440 Genome-wide genotyping array 324933 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Autoimmune thyroid disease 607 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 autoimmune thyroid disease http://www.ebi.ac.uk/efo/EFO_0006812 GCST90014441 Genome-wide genotyping array 324681 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Celiac disease 2,364 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 celiac disease http://www.ebi.ac.uk/efo/EFO_0001060 GCST90014442 Genome-wide genotyping array 326438 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Celiac disease 1,260 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 celiac disease http://www.ebi.ac.uk/efo/EFO_0001060 GCST90014443 Genome-wide genotyping array 325334 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Inflammatory bowel disease 5,105 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 inflammatory bowel disease http://www.ebi.ac.uk/efo/EFO_0003767 GCST90014444 Genome-wide genotyping array 329179 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Inflammatory bowel disease 3,538 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 inflammatory bowel disease http://www.ebi.ac.uk/efo/EFO_0003767 GCST90014445 Genome-wide genotyping array 327612 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Myasthenia gravis 234 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 Myasthenia gravis http://www.ebi.ac.uk/efo/EFO_0004991 GCST90014446 Genome-wide genotyping array 324308 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Myasthenia gravis 147 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 Myasthenia gravis http://www.ebi.ac.uk/efo/EFO_0004991 GCST90014447 Genome-wide genotyping array 324221 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Multiple sclerosis 1,683 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST90014448 Genome-wide genotyping array 325757 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Multiple sclerosis 1,154 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST90014449 Genome-wide genotyping array 325228 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Pernicious anemia 1,555 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 pernicious anemia http://www.ebi.ac.uk/efo/EFO_0005576 GCST90014450 Genome-wide genotyping array 325629 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Pernicious anemia 423 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 pernicious anemia http://www.ebi.ac.uk/efo/EFO_0005576 GCST90014451 Genome-wide genotyping array 324497 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Polymyalgia rheumatica 1,627 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 polymyalgia rheumatica http://www.ebi.ac.uk/efo/EFO_0008518 GCST90014452 Genome-wide genotyping array 325701 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Polymyalgia rheumatica 898 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 polymyalgia rheumatica http://www.ebi.ac.uk/efo/EFO_0008518 GCST90014453 Genome-wide genotyping array 324972 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Psoriatic arthritis 1,107 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 psoriatic arthritis http://www.ebi.ac.uk/efo/EFO_0003778 GCST90014454 Genome-wide genotyping array 325181 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Psoriatic arthritis 779 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 psoriatic arthritis http://www.ebi.ac.uk/efo/EFO_0003778 GCST90014455 Genome-wide genotyping array 324853 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Psoriasis 5,459 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 psoriasis http://www.ebi.ac.uk/efo/EFO_0000676 GCST90014456 Genome-wide genotyping array 329533 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Psoriasis 2,759 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 psoriasis http://www.ebi.ac.uk/efo/EFO_0000676 GCST90014457 Genome-wide genotyping array 326833 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Rheumatoid arthritis 6,360 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST90014458 Genome-wide genotyping array 330434 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Rheumatoid arthritis 3,451 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST90014459 Genome-wide genotyping array 327525 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Sjögren's syndrome 647 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 Sjogren syndrome http://www.ebi.ac.uk/efo/EFO_0000699 GCST90014460 Genome-wide genotyping array 324721 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Sjögren's syndrome 389 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 Sjogren syndrome http://www.ebi.ac.uk/efo/EFO_0000699 GCST90014461 Genome-wide genotyping array 324463 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Systemic lupus erythematosus 624 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST90014462 Genome-wide genotyping array 324698 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Systemic lupus erythematosus 362 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST90014463 Genome-wide genotyping array 324436 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Type 1 diabetes 2,751 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001359 GCST90014464 Genome-wide genotyping array 326825 2021-07-26 34278373 Glanville KP 2021-06-01 Biol Psychiatry Glob Open Sci www.ncbi.nlm.nih.gov/pubmed/34278373 Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank. Type 1 diabetes 2,292 European ancestry cases, 324,074 European ancestry controls NA NR [9940918] (imputed) 0 type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001359 GCST90014465 Genome-wide genotyping array 326366 2021-07-27 34187846 Ong JS 2021-06-29 Gut www.ncbi.nlm.nih.gov/pubmed/34187846 Multitrait genetic association analysis identifies 50 new risk loci for gastro-oesophageal reflux, seven new loci for Barrett's oesophagus and provides insights into clinical heterogeneity in reflux diagnosis. Gastroesophageal reflux disease 129,080 European ancestry cases, 473,524 European ancestry controls 462,753 cases, 1,127,474 controls NR [2324712] (imputed) 37 gastroesophageal reflux disease http://www.ebi.ac.uk/efo/EFO_0003948 GCST90000514 Genome-wide genotyping array 602604 2021-07-27 34187846 Ong JS 2021-06-29 Gut www.ncbi.nlm.nih.gov/pubmed/34187846 Multitrait genetic association analysis identifies 50 new risk loci for gastro-oesophageal reflux, seven new loci for Barrett's oesophagus and provides insights into clinical heterogeneity in reflux diagnosis. Barrett's esophagus 13,358 European ancestry cases, 43,071 European ancestry controls 24,099 cases, 1,484,025 controls NR [2324712] (imputed) 8 Barrett's esophagus http://www.ebi.ac.uk/efo/EFO_0000280 GCST90000515 Genome-wide genotyping array 56429 2021-10-21 34159505 Wang H 2021-06-16 Sci China Life Sci www.ncbi.nlm.nih.gov/pubmed/34159505 Novel loci and potential mechanisms of major depressive disorder, bipolar disorder, and schizophrenia. Major depressive disorder (MTAG) 119,754 European ancestry individuals NA NR [2625067] 11 major depressive disorder http://purl.obolibrary.org/obo/MONDO_0002009 GCST90020093 Genome-wide genotyping array 119754 2021-10-21 34159505 Wang H 2021-06-16 Sci China Life Sci www.ncbi.nlm.nih.gov/pubmed/34159505 Novel loci and potential mechanisms of major depressive disorder, bipolar disorder, and schizophrenia. Bipolar disorder (MTAG) 1,450,972 European ancestry individuals NA NR [2625067] 49 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST90020094 Genome-wide genotyping array 1450972 2021-10-21 34159505 Wang H 2021-06-16 Sci China Life Sci www.ncbi.nlm.nih.gov/pubmed/34159505 Novel loci and potential mechanisms of major depressive disorder, bipolar disorder, and schizophrenia. Schizophrenia (MTAG) 940,613 European ancestry individuals NA NR [2625067] 90 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST90020095 Genome-wide genotyping array 940613 2021-06-24 34054925 Cho HW 2021-05-13 Front Genet www.ncbi.nlm.nih.gov/pubmed/34054925 A Genome-Wide Association Study of Novel Genetic Variants Associated With Anthropometric Traits in Koreans. Height 2,603 Korean ancestry males, 2,869 Korean ancestry females 19,571 Korean ancestry males, 37,321 Korean ancestry females NR [8056211] (imputed) 67 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST011972 Genome-wide genotyping array 5472 2021-06-24 34054925 Cho HW 2021-05-13 Front Genet www.ncbi.nlm.nih.gov/pubmed/34054925 A Genome-Wide Association Study of Novel Genetic Variants Associated With Anthropometric Traits in Koreans. Weight 2,603 Korean ancestry males, 2,869 Korean ancestry females 19,571 Korean ancestry males, 37,321 Korean ancestry females NR [8056211] (imputed) 21 body weight http://www.ebi.ac.uk/efo/EFO_0004338 GCST011971 Genome-wide genotyping array 5472 2021-06-24 34054925 Cho HW 2021-05-13 Front Genet www.ncbi.nlm.nih.gov/pubmed/34054925 A Genome-Wide Association Study of Novel Genetic Variants Associated With Anthropometric Traits in Koreans. Body mass index 5,472 Korean ancestry individuals 56,892 Korean ancestry individuals NR [8056211] (imputed) 0 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST011970 Genome-wide genotyping array 5472 2021-06-24 34054925 Cho HW 2021-05-13 Front Genet www.ncbi.nlm.nih.gov/pubmed/34054925 A Genome-Wide Association Study of Novel Genetic Variants Associated With Anthropometric Traits in Koreans. Waist circumference 5,472 Korean ancestry individuals 56,892 Korean ancestry individuals NR [8056211] (imputed) 0 waist circumference http://www.ebi.ac.uk/efo/EFO_0004342 GCST011969 Genome-wide genotyping array 5472 2021-06-24 34054925 Cho HW 2021-05-13 Front Genet www.ncbi.nlm.nih.gov/pubmed/34054925 A Genome-Wide Association Study of Novel Genetic Variants Associated With Anthropometric Traits in Koreans. Hip circumference 5,472 Korean ancestry individuals 56,892 Korean ancestry individuals NR [8056211] (imputed) 0 hip circumference http://www.ebi.ac.uk/efo/EFO_0005093 GCST011968 Genome-wide genotyping array 5472 2021-06-24 34054925 Cho HW 2021-05-13 Front Genet www.ncbi.nlm.nih.gov/pubmed/34054925 A Genome-Wide Association Study of Novel Genetic Variants Associated With Anthropometric Traits in Koreans. Waist-hip ratio 2,603 Korean ancestry males, 2,869 Korean ancestry females 19,571 Korean ancestry males, 37,321 Korean ancestry females NR [8056211] (imputed) 1 waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0004343 GCST011967 Genome-wide genotyping array 5472 2021-06-24 34054925 Cho HW 2021-05-13 Front Genet www.ncbi.nlm.nih.gov/pubmed/34054925 A Genome-Wide Association Study of Novel Genetic Variants Associated With Anthropometric Traits in Koreans. Waist circumference adjusted for body mass index 5,472 Korean ancestry individuals 56,892 Korean ancestry individuals NR [8056211] (imputed) 0 BMI-adjusted waist circumference http://www.ebi.ac.uk/efo/EFO_0007789 GCST011966 Genome-wide genotyping array 5472 2021-06-24 34054925 Cho HW 2021-05-13 Front Genet www.ncbi.nlm.nih.gov/pubmed/34054925 A Genome-Wide Association Study of Novel Genetic Variants Associated With Anthropometric Traits in Koreans. Hip circumference adjusted for BMI 5,472 Korean ancestry individuals 56,892 Korean ancestry individuals NR [8056211] (imputed) 0 BMI-adjusted hip circumference http://www.ebi.ac.uk/efo/EFO_0008039 GCST011965 Genome-wide genotyping array 5472 2021-06-24 34054925 Cho HW 2021-05-13 Front Genet www.ncbi.nlm.nih.gov/pubmed/34054925 A Genome-Wide Association Study of Novel Genetic Variants Associated With Anthropometric Traits in Koreans. Waist-to-hip ratio adjusted for BMI 2,603 Korean ancestry males, 2,869 Korean ancestry females 19,571 Korean ancestry males, 37,321 Korean ancestry females NR [8056211] (imputed) 5 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST011964 Genome-wide genotyping array 5472 2021-11-02 34476894 Schmitz J 2021-09-03 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/34476894 Genome-wide association study and polygenic risk score analysis for hearing measures in children. Hearing function 5,344 European ancestry children NA Illumina [5305352] (imputed) 10 hearing threshold measurement http://www.ebi.ac.uk/efo/EFO_0007618 GCST90029040 Genome-wide genotyping array 5344 2021-11-02 34476894 Schmitz J 2021-09-03 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/34476894 Genome-wide association study and polygenic risk score analysis for hearing measures in children. Hearing function (left/right asymmetry) 5,344 European ancestry children NA Illumina [5305352] (imputed) 9 hearing threshold measurement http://www.ebi.ac.uk/efo/EFO_0007618 GCST90029041 Genome-wide genotyping array 5344 2021-06-25 33034629 Khoury S 2020-10-09 Sleep www.ncbi.nlm.nih.gov/pubmed/33034629 Multi-ethnic GWAS and meta-analysis of sleep quality identify MPP6 as a novel gene that functions in sleep center neurons. Sleep quality 1,676 non-Hispanic white individuals, 740 African American individuals, 146 Hispanic individuals, 306 individuals 158,207 European ancestry individuals, 16,000 Hispanic individuals, 5,151 African American individuals Illumina [35000000] (imputed) 0 sleep quality http://www.ebi.ac.uk/efo/EFO_0005272 GCST011976 Genome-wide genotyping array 2868 2021-06-01 33909500 Moll M 2021-04-28 Am J Physiol Lung Cell Mol Physiol www.ncbi.nlm.nih.gov/pubmed/33909500 A Systematic Analysis of Protein-altering Exonic Variants in Chronic Obstructive Pulmonary Disease. Chronic obstructive pulmonary disease up to 31,465 European ancestry cases, up to 203,688 European ancestry controls, up to 1,413 African ancestry cases, up to 6,080 African ancestry controls, up to 287 East Asian ancestry cases, up to 7,484 East Asian ancestry controls, up to 61 Hispanic cases, up to 613 Hispanic controls NA Illumina [at least 109036] 35 chronic obstructive pulmonary disease http://www.ebi.ac.uk/efo/EFO_0000341 GCST011766 Exome genotyping array [Exome array] 251091 2021-10-04 34014961 Palmer ND 2021-05-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/34014961 Genome-wide association study of vitamin D concentrations and bone mineral density in the African American-Diabetes Heart Study. Serum 25-Hydroxyvitamin D levels in type 2 diabetes 697 African American individuals 554 African American individuals Illumina [3436913] (imputed) 0 vitamin D measurement http://www.ebi.ac.uk/efo/EFO_0004631 GCST012428 Genome-wide genotyping array 697 2021-10-04 34014961 Palmer ND 2021-05-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/34014961 Genome-wide association study of vitamin D concentrations and bone mineral density in the African American-Diabetes Heart Study. 1,25-dihydroxycholecalciferol levels in type 2 diabetes 697 African American individuals 554 African American individuals Illumina [3436913] (imputed) 0 vitamin D measurement http://www.ebi.ac.uk/efo/EFO_0004631 GCST012427 Genome-wide genotyping array 697 2021-10-04 34014961 Palmer ND 2021-05-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/34014961 Genome-wide association study of vitamin D concentrations and bone mineral density in the African American-Diabetes Heart Study. Serum vitamin D-binding protein levels in type 2 diabetes 697 African American individuals NA Illumina [3436913] (imputed) 3 vitamin D-binding protein measurement http://www.ebi.ac.uk/efo/EFO_0005675 GCST012426 Genome-wide genotyping array 697 2021-10-04 34014961 Palmer ND 2021-05-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/34014961 Genome-wide association study of vitamin D concentrations and bone mineral density in the African American-Diabetes Heart Study. Bioavailable vitamin D levels in type 2 diabetes 697 African American individuals NA Illumina [3436913] (imputed) 1 vitamin D measurement http://www.ebi.ac.uk/efo/EFO_0004631 GCST012425 Genome-wide genotyping array 697 2021-10-04 34014961 Palmer ND 2021-05-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/34014961 Genome-wide association study of vitamin D concentrations and bone mineral density in the African American-Diabetes Heart Study. Intact parathyroid hormone levels in type 2 diabetes 697 African American individuals NA Illumina [3436913] (imputed) 0 parathyroid hormone measurement http://www.ebi.ac.uk/efo/EFO_0004752 GCST012424 Genome-wide genotyping array 697 2021-10-04 34014961 Palmer ND 2021-05-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/34014961 Genome-wide association study of vitamin D concentrations and bone mineral density in the African American-Diabetes Heart Study. Thoracic volumetric BMD in type 2 diabetes 697 African American individuals NA Illumina [3436913] (imputed) 0 volumetric bone mineral density http://www.ebi.ac.uk/efo/EFO_0007620 GCST012423 Genome-wide genotyping array 697 2021-10-04 34014961 Palmer ND 2021-05-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/34014961 Genome-wide association study of vitamin D concentrations and bone mineral density in the African American-Diabetes Heart Study. Lumbar volumetric BMD in type 2 diabetes 697 African American individuals NA Illumina [3436913] (imputed) 0 volumetric bone mineral density http://www.ebi.ac.uk/efo/EFO_0007620 GCST012422 Genome-wide genotyping array 697 2021-09-02 34018994 Xu JK 2021-03-22 Chin Med J (Engl) www.ncbi.nlm.nih.gov/pubmed/34018994 Genome-wide long non-coding RNA association study on Han Chinese women identifies lncHSAT164 as a novel susceptibility gene for breast cancer. Breast cancer 1,496 Han Chinese ancestry cases, 1,257 Han Chinese ancestry controls 4,138 Han Chinese ancestry cases, 5,051 Han Chinese ancestry controls Illumina [up to 800000] 4 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST012281 Targeted genotyping array 2753 2021-06-14 30653739 Sofer T 2019-01-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30653739 A fully adjusted two-stage procedure for rank-normalization in genetic association studies. Number of natural teeth 12,595 Hispanic individuals NA Illumina [at least 2232944] (imputed) 0 number of teeth measurement http://www.ebi.ac.uk/efo/EFO_0010073 GCST011877 Genome-wide genotyping array 12595 2021-06-14 30653739 Sofer T 2019-01-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30653739 A fully adjusted two-stage procedure for rank-normalization in genetic association studies. Body mass index 12,595 Hispanic individuals NA Illumina [at least 2232944] (imputed) 0 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST011876 Genome-wide genotyping array 12595 2021-06-14 30653739 Sofer T 2019-01-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30653739 A fully adjusted two-stage procedure for rank-normalization in genetic association studies. Height 12,595 Hispanic individuals NA Illumina [at least 2232944] (imputed) 0 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST011875 Genome-wide genotyping array 12595 2021-06-14 30653739 Sofer T 2019-01-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30653739 A fully adjusted two-stage procedure for rank-normalization in genetic association studies. Hip circumference adjusted for BMI 12,595 Hispanic individuals NA Illumina [at least 2232944] (imputed) 0 BMI-adjusted hip circumference http://www.ebi.ac.uk/efo/EFO_0008039 GCST011874 Genome-wide genotyping array 12595 2021-06-14 30653739 Sofer T 2019-01-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30653739 A fully adjusted two-stage procedure for rank-normalization in genetic association studies. Waist circumference adjusted for body mass index 12,595 Hispanic individuals NA Illumina [at least 2232944] (imputed) 0 BMI-adjusted waist circumference http://www.ebi.ac.uk/efo/EFO_0007789 GCST011873 Genome-wide genotyping array 12595 2021-06-14 30653739 Sofer T 2019-01-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30653739 A fully adjusted two-stage procedure for rank-normalization in genetic association studies. Waist-hip ratio 12,595 Hispanic individuals NA Illumina [at least 2232944] (imputed) 0 waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0004343 GCST011872 Genome-wide genotyping array 12595 2021-06-14 30653739 Sofer T 2019-01-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30653739 A fully adjusted two-stage procedure for rank-normalization in genetic association studies. Diastolic blood pressure 12,595 Hispanic individuals NA Illumina [at least 2232944] (imputed) 0 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST011871 Genome-wide genotyping array 12595 2021-06-14 30653739 Sofer T 2019-01-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30653739 A fully adjusted two-stage procedure for rank-normalization in genetic association studies. Systolic blood pressure 12,595 Hispanic individuals NA Illumina [at least 2232944] (imputed) 0 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST011870 Genome-wide genotyping array 12595 2021-06-14 30653739 Sofer T 2019-01-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30653739 A fully adjusted two-stage procedure for rank-normalization in genetic association studies. Ferritin levels 12,595 Hispanic individuals NA Illumina [at least 2232944] (imputed) 0 ferritin measurement http://www.ebi.ac.uk/efo/EFO_0004459 GCST011869 Genome-wide genotyping array 12595 2021-06-14 30653739 Sofer T 2019-01-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30653739 A fully adjusted two-stage procedure for rank-normalization in genetic association studies. Iron status biomarkers (transferrin levels) 12,595 Hispanic individuals NA Illumina [at least 2232944] (imputed) 0 transferrin measurement http://www.ebi.ac.uk/efo/EFO_0006341 GCST011868 Genome-wide genotyping array 12595 2021-06-14 30653739 Sofer T 2019-01-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30653739 A fully adjusted two-stage procedure for rank-normalization in genetic association studies. Iron status biomarkers (total iron binding capacity) 12,595 Hispanic individuals NA Illumina [at least 2232944] (imputed) 0 total iron binding capacity http://www.ebi.ac.uk/efo/EFO_0006334 GCST011867 Genome-wide genotyping array 12595 2021-06-14 30653739 Sofer T 2019-01-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30653739 A fully adjusted two-stage procedure for rank-normalization in genetic association studies. Glycated hemoglobin levels 12,595 Hispanic individuals NA Illumina [at least 2232944] (imputed) 0 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST011866 Genome-wide genotyping array 12595 2021-06-14 30653739 Sofer T 2019-01-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30653739 A fully adjusted two-stage procedure for rank-normalization in genetic association studies. High density lipoprotein cholesterol levels 12,595 Hispanic individuals NA Illumina [at least 2232944] (imputed) 0 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST011865 Genome-wide genotyping array 12595 2021-06-14 30653739 Sofer T 2019-01-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30653739 A fully adjusted two-stage procedure for rank-normalization in genetic association studies. Low density lipoprotein cholesterol levels 12,595 Hispanic individuals NA Illumina [at least 2232944] (imputed) 0 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST011864 Genome-wide genotyping array 12595 2021-06-14 30653739 Sofer T 2019-01-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30653739 A fully adjusted two-stage procedure for rank-normalization in genetic association studies. Triglycerides 12,595 Hispanic individuals NA Illumina [at least 2232944] (imputed) 0 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST011863 Genome-wide genotyping array 12595 2021-06-14 30653739 Sofer T 2019-01-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30653739 A fully adjusted two-stage procedure for rank-normalization in genetic association studies. Total cholesterol levels 12,595 Hispanic individuals NA Illumina [at least 2232944] (imputed) 0 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST011862 Genome-wide genotyping array 12595 2021-06-14 30653739 Sofer T 2019-01-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30653739 A fully adjusted two-stage procedure for rank-normalization in genetic association studies. Heart rate 12,595 Hispanic individuals NA Illumina [at least 2232944] (imputed) 0 heart rate http://www.ebi.ac.uk/efo/EFO_0004326 GCST011861 Genome-wide genotyping array 12595 2021-06-14 30653739 Sofer T 2019-01-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30653739 A fully adjusted two-stage procedure for rank-normalization in genetic association studies. QT interval 12,595 Hispanic individuals NA Illumina [at least 2232944] (imputed) 0 QT interval http://www.ebi.ac.uk/efo/EFO_0004682 GCST011860 Genome-wide genotyping array 12595 2021-06-14 30653739 Sofer T 2019-01-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30653739 A fully adjusted two-stage procedure for rank-normalization in genetic association studies. PR interval 12,595 Hispanic individuals NA Illumina [at least 2232944] (imputed) 0 PR interval http://www.ebi.ac.uk/efo/EFO_0004462 GCST011859 Genome-wide genotyping array 12595 2021-06-14 30653739 Sofer T 2019-01-17 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/30653739 A fully adjusted two-stage procedure for rank-normalization in genetic association studies. Mean corpuscular hemoglobin concentration 12,595 Hispanic individuals NA Illumina [at least 2232944] (imputed) 0 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST011858 Genome-wide genotyping array 12595 2021-10-21 34532061 Hodel F 2021-06-11 Virus Evol www.ncbi.nlm.nih.gov/pubmed/34532061 Human genomics of the humoral immune response against polyomaviruses. Anti-BK polyomavirus IgG seropositivity 14,249 European ancestry antibody-positive cases, up to 1,154 European ancestry antibody-negative controls NA Affymetrix [NR] (imputed) 0 BK polyomavirus seropositivity http://www.ebi.ac.uk/efo/EFO_0010905 GCST90032662 Genome-wide genotyping array 15403 2021-10-21 34532061 Hodel F 2021-06-11 Virus Evol www.ncbi.nlm.nih.gov/pubmed/34532061 Human genomics of the humoral immune response against polyomaviruses. BK polyomavirus VP1 antibody levels 14,249 European ancestry individuals NA Affymetrix [NR] (imputed) 1 anti-BK polyomavirus antibody measurement http://www.ebi.ac.uk/efo/EFO_0010904 GCST90032663 Genome-wide genotyping array 14249 2021-10-21 34532061 Hodel F 2021-06-11 Virus Evol www.ncbi.nlm.nih.gov/pubmed/34532061 Human genomics of the humoral immune response against polyomaviruses. Anti-human polyomavirus 6 IgG seropositivity 5,094 European ancestry antibody-positive cases, up to 958 European ancestry antibody-negative controls NA Affymetrix [NR] (imputed) 0 NA NA GCST90032664 Genome-wide genotyping array 6052 2021-10-21 34532061 Hodel F 2021-06-11 Virus Evol www.ncbi.nlm.nih.gov/pubmed/34532061 Human genomics of the humoral immune response against polyomaviruses. Human polyomavirus 6 VP1 antibody levels 5,094 European ancestry individuals NA Affymetrix [NR] (imputed) 5 NA NA GCST90032665 Genome-wide genotyping array 5094 2021-10-21 34532061 Hodel F 2021-06-11 Virus Evol www.ncbi.nlm.nih.gov/pubmed/34532061 Human genomics of the humoral immune response against polyomaviruses. Anti-JC polyomavirus IgG seropositivity 8,567 European ancestry antibody-positive cases cases, up to 6,836 European ancestry antibody-negative controls NA Affymetrix [NR] (imputed) 19 polyomavirus 2 seropositivity http://www.ebi.ac.uk/efo/EFO_0010907 GCST90032666 Genome-wide genotyping array 15403 2021-10-21 34532061 Hodel F 2021-06-11 Virus Evol www.ncbi.nlm.nih.gov/pubmed/34532061 Human genomics of the humoral immune response against polyomaviruses. JC polyomavirus VP1 antibody levels 8,567 European ancestry individuals NA Affymetrix [NR] (imputed) 7 anti-polyomavirus 2 antibody measurement http://www.ebi.ac.uk/efo/EFO_0010900 GCST90032667 Genome-wide genotyping array 8567 2021-10-21 34532061 Hodel F 2021-06-11 Virus Evol www.ncbi.nlm.nih.gov/pubmed/34532061 Human genomics of the humoral immune response against polyomaviruses. Anti-Merkel cell polyomavirus IgG seropositivity 8,091 European ancestry antibody-positive cases, up to 3,623 European ancestry antibody-negative controls NA Affymetrix [NR] (imputed) 14 merkel cell virus seropositivity http://www.ebi.ac.uk/efo/EFO_0010906 GCST90032668 Genome-wide genotyping array 11714 2021-10-21 34532061 Hodel F 2021-06-11 Virus Evol www.ncbi.nlm.nih.gov/pubmed/34532061 Human genomics of the humoral immune response against polyomaviruses. Merkel cell polyomavirus VP1 antibody levels 8,091 European ancestry individuals NA Affymetrix [NR] (imputed) 15 anti-merkel cell virus antibody measurement http://www.ebi.ac.uk/efo/EFO_0010899 GCST90032669 Genome-wide genotyping array 8091 2021-10-21 34532061 Hodel F 2021-06-11 Virus Evol www.ncbi.nlm.nih.gov/pubmed/34532061 Human genomics of the humoral immune response against polyomaviruses. WU polyomavirus VP1 antibody levels 5,791 European ancestry individuals NA Affymetrix [NR] (imputed) 1 NA NA GCST90032670 Genome-wide genotyping array 5791 2021-10-04 34064523 Rodrigo LM 2021-05-04 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/34064523 Imputation and Reanalysis of ExomeChip Data Identifies Novel, Conditional and Joint Genetic Effects on Parkinson's Disease Risk. Parkinson's disease 5,167 European ancestry cases, 5,366 European ancestry controls NA Illumina [1465938] (imputed) 14 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST012431 Genome-wide genotyping array 10533 2021-09-14 34465887 Wu P 2021-08-31 Commun Biol www.ncbi.nlm.nih.gov/pubmed/34465887 Trans-ethnic genome-wide association study of severe COVID-19. Severe COVID-19 infection 65 Chinese ancestry cases, 138 Chinese ancestry controls NA NR [5056041] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST90014052 Genome-wide sequencing 203 2021-09-14 34465887 Wu P 2021-08-31 Commun Biol www.ncbi.nlm.nih.gov/pubmed/34465887 Trans-ethnic genome-wide association study of severe COVID-19. Asymptomatic COVID-19 infection 63 Chinese ancestry cases, 140 Chinese ancestry controls NA NR [5056041] 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST90014053 Genome-wide sequencing 203 2021-11-17 33723576 Carrera C 2021-03-16 Brain www.ncbi.nlm.nih.gov/pubmed/33723576 Single nucleotide variations in ZBTB46 are associated with post-thrombolytic parenchymal haematoma. Parenchymal hematoma in thrombolytic-treated acute ischaemic stroke 71 European ancestry cases, 1,253 European ancestry controls 70 European ancestry cases, 510 European ancestry controls Illumina [7989272] (imputed) 6 NA NA GCST90027882 Genome-wide genotyping array 1324 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. High light scatter reticulocyte count 437,723 European ancestry individuals NA NR [9800000] (imputed) 29 reticulocyte count http://www.ebi.ac.uk/efo/EFO_0007986 GCST90025970 Genome-wide genotyping array 437723 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Immature fraction of reticulocytes 438,154 European ancestry individuals NA NR [9800000] (imputed) 9 Immature Reticulocyte Fraction Measurement http://www.ebi.ac.uk/efo/EFO_0009253 GCST90025971 Genome-wide genotyping array 438154 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Reticulocyte count 437,291 European ancestry individuals NA NR [9800000] (imputed) 31 reticulocyte count http://www.ebi.ac.uk/efo/EFO_0007986 GCST90025972 Genome-wide genotyping array 437291 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Bilirubin levels 436,055 European ancestry individuals NA NR [9800000] (imputed) 16 bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004570 GCST90025973 Genome-wide genotyping array 436055 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Hemoglobin A1c levels 437,749 European ancestry individuals NA NR [9800000] (imputed) 36 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST90025974 Genome-wide genotyping array 437749 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Mean reticulocyte volume 436,944 European ancestry individuals NA NR [9800000] (imputed) 19 mean reticulocyte volume http://www.ebi.ac.uk/efo/EFO_0010701 GCST90025975 Genome-wide genotyping array 436944 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Mean sphered cell volume 437,736 European ancestry individuals NA NR [9800000] (imputed) 22 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST90025976 Genome-wide genotyping array 437736 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Neutrophil count 443,782 European ancestry individuals NA NR [9800000] (imputed) 13 neutrophil count http://www.ebi.ac.uk/efo/EFO_0004833 GCST90025977 Genome-wide genotyping array 443782 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Lung function (FEV1/FVC) 371,898 European ancestry individuals NA NR [9800000] (imputed) 4 FEV/FEC ratio http://www.ebi.ac.uk/efo/EFO_0004713 GCST90025978 Genome-wide genotyping array 371898 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Alanine aminotransferase levels 437,724 European ancestry individuals NA NR [9800000] (imputed) 20 serum alanine aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004735 GCST90025979 Genome-wide genotyping array 437724 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Aspartate aminotransferase levels 436,275 European ancestry individuals NA NR [9800000] (imputed) 14 aspartate aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004736 GCST90025980 Genome-wide genotyping array 436275 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Diastolic blood pressure 422,713 European ancestry individuals NA NR [9800000] (imputed) 7 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST90025981 Genome-wide genotyping array 422713 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Heel bone mineral density T score 445,855 European ancestry individuals NA NR [9800000] (imputed) 11 heel bone mineral density http://www.ebi.ac.uk/efo/EFO_0009270 GCST90025982 Genome-wide genotyping array 445855 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Direct bilirubin levels 372,420 European ancestry individuals NA NR [9800000] (imputed) 8 bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004570 GCST90025983 Genome-wide genotyping array 372420 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Lymphocyte counts 443,762 European ancestry individuals NA NR [9800000] (imputed) 16 lymphocyte count http://www.ebi.ac.uk/efo/EFO_0004587 GCST90025984 Genome-wide genotyping array 443762 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. White blood cell count 444,734 European ancestry individuals NA NR [9800000] (imputed) 17 leukocyte count http://www.ebi.ac.uk/efo/EFO_0004308 GCST90025985 Genome-wide genotyping array 444734 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Blood glucose levels 400,458 European ancestry individuals NA NR [9800000] (imputed) 6 glucose measurement http://www.ebi.ac.uk/efo/EFO_0004468 GCST90025986 Genome-wide genotyping array 400458 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Eosinophil counts 440,275 European ancestry individuals NA NR [9800000] (imputed) 14 eosinophil count http://www.ebi.ac.uk/efo/EFO_0004842 GCST90025987 Genome-wide genotyping array 440275 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Red cell distribution width 441,263 European ancestry individuals NA NR [9800000] (imputed) 24 red blood cell distribution width http://www.ebi.ac.uk/efo/EFO_0005192 GCST90025988 Genome-wide genotyping array 441263 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Insulin-like growth factor 1 levels 435,516 European ancestry individuals NA NR [9800000] (imputed) 29 IGF-1 measurement http://www.ebi.ac.uk/efo/EFO_0004627 GCST90025989 Genome-wide genotyping array 435516 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Calcium levels 400,792 European ancestry individuals NA NR [9800000] (imputed) 7 calcium measurement http://www.ebi.ac.uk/efo/EFO_0004838 GCST90025990 Genome-wide genotyping array 400792 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Serum urea levels 437,580 European ancestry individuals NA NR [9800000] (imputed) 3 serum urea measurement http://www.ebi.ac.uk/efo/EFO_0009795 GCST90025991 Genome-wide genotyping array 437580 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Serum albumin levels 400,938 European ancestry individuals NA NR [9800000] (imputed) 10 serum albumin measurement http://www.ebi.ac.uk/efo/EFO_0004535 GCST90025992 Genome-wide genotyping array 400938 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Lipoprotein (a) levels 348,806 European ancestry individuals NA NR [9800000] (imputed) 7 lipoprotein A measurement http://www.ebi.ac.uk/efo/EFO_0006925 GCST90025993 Genome-wide genotyping array 348806 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Body mass index 457,756 European ancestry individuals NA NR [9800000] (imputed) 3 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST90025994 Genome-wide genotyping array 457756 2021-10-06 34130359 Curtis SW 2021-06-15 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/34130359 FAT4 identified as a potential modifier of orofacial cleft laterality. Unilateral cleft lip and palate (left vs right) 98 Asian ancestry LCLP cases, 199 European ancestry LCLP cases, 340 Hispanic LCLP cases, 1 LCLP case, 59 Asian ancestry RCLP cases, 94 European ancestry RCLP cases, 263 Hispanic RCLP cases 428 LCLP cases, 250 RCLP cases Illumina [539473] (imputed) 0 Cleft palate, cleft lip http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959 GCST012452 Genome-wide genotyping array 1054 2021-10-06 34130359 Curtis SW 2021-06-15 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/34130359 FAT4 identified as a potential modifier of orofacial cleft laterality. Left unilateral cleft lip and palate 98 Asian ancestry cases, 199 European ancestry cases, 340 Hispanic cases, 1 case, 1,626 controls NA Illumina [539473] (imputed) 22 Cleft palate, cleft lip http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959 GCST012457 Genome-wide genotyping array 2264 2021-06-23 34103634 Valette K 2021-06-08 Commun Biol www.ncbi.nlm.nih.gov/pubmed/34103634 Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank. Asthma 56,167 White-British ancestry cases, 352,255 White-British ancestry controls NA Affymetrix [35186738] (imputed) 73 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST90014325 Genome-wide genotyping array 408422 2021-10-06 34130359 Curtis SW 2021-06-15 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/34130359 FAT4 identified as a potential modifier of orofacial cleft laterality. Unilateral cleft lip (left vs right) 68 Asian ancestry LCL cases, 78 European ancestry LCL cases, 70 Hispanic LCL cases, 43 Asian ancestry RCL cases, 40 European ancestry RCL cases, 47 Hispanic RCL cases 219 LCL cases, 107 RCL cases Illumina [539473] (imputed) 0 cleft lip http://www.ebi.ac.uk/efo/EFO_0003959 GCST012453 Genome-wide genotyping array 346 2021-10-06 34130359 Curtis SW 2021-06-15 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/34130359 FAT4 identified as a potential modifier of orofacial cleft laterality. Right unilateral cleft lip 43 Asian ancestry cases, 40 European ancestry cases, 47 Hispanic cases, 1,626 controls NA Illumina [539473] (imputed) 21 cleft lip http://www.ebi.ac.uk/efo/EFO_0003959 GCST012458 Genome-wide genotyping array 1756 2021-10-06 34130359 Curtis SW 2021-06-15 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/34130359 FAT4 identified as a potential modifier of orofacial cleft laterality. Left unilateral cleft lip 68 Asian ancestry cases, 78 European ancestry cases, 70 Hispanic cases, 1,626 controls NA Illumina [539473] (imputed) 32 cleft lip http://www.ebi.ac.uk/efo/EFO_0003959 GCST012456 Genome-wide genotyping array 1842 2021-10-06 34130359 Curtis SW 2021-06-15 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/34130359 FAT4 identified as a potential modifier of orofacial cleft laterality. Right unilateral cleft lip and palate 59 Asian ancestry cases, 94 European ancestry cases, 263 Hispanic cases, 1,626 controls NA Illumina [539473] (imputed) 22 Cleft palate, cleft lip http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959 GCST012455 Genome-wide genotyping array 2042 2021-10-06 34130359 Curtis SW 2021-06-15 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/34130359 FAT4 identified as a potential modifier of orofacial cleft laterality. Cleft lip with or without cleft palate (bilateral vs unilateral) 98 Asian ancestry LCLP cases, 199 European ancestry LCLP cases, 340 Hispanic LCLP cases, 1 LCLP case, 59 Asian ancestry RCLP cases, 94 European ancestry RCLP cases, 263 Hispanic RCLP cases, 68 Asian ancestry LCL cases, 78 European ancestry LCL cases, 70 Hispanic LCL cases, 43 Asian ancestry RCL cases, 40 European ancestry RCL cases, 47 Hispanic RCL cases 428 LCLP cases, 250 RCLP cases, 219 LCL cases, 107 RCL cases Illumina [539473] (imputed) 0 Cleft palate, cleft lip http://purl.obolibrary.org/obo/HP_0000175, http://www.ebi.ac.uk/efo/EFO_0003959 GCST012454 Genome-wide genotyping array 1400 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Serum total protein level 400,482 European ancestry individuals NA NR [9800000] (imputed) 9 total blood protein measurement http://www.ebi.ac.uk/efo/EFO_0004536 GCST90025995 Genome-wide genotyping array 400482 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Waist-to-hip ratio adjusted for BMI 458,349 European ancestry individuals NA NR [9800000] (imputed) 4 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST90025996 Genome-wide genotyping array 458349 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Basophil count 438,607 European ancestry individuals NA NR [9800000] (imputed) 3 basophil count http://www.ebi.ac.uk/efo/EFO_0005090 GCST90025997 Genome-wide genotyping array 438607 2021-11-16 34226706 Barton AR 2021-07-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34226706 Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses. Lung function (FVC) 371,898 European ancestry individuals NA NR [9800000] (imputed) 3 vital capacity http://www.ebi.ac.uk/efo/EFO_0004312 GCST90025998 Genome-wide genotyping array 371898 2021-10-14 34288885 Lin WD 2021-07-01 Eur J Endocrinol www.ncbi.nlm.nih.gov/pubmed/34288885 Genetic factors of idiopathic central precocious puberty and their polygenic risk in early puberty. Idiopathic central precocious puberty 256 Han Chinese ancestry cases, 118 Han Chinese ancestry controls 65 Han Chinese ancestry cases, 30 Han Chinese ancestry controls Affymetrix [NR] (imputed) 14 Central precocious puberty http://www.ebi.ac.uk/efo/EFO_0009029 GCST90027238 Genome-wide genotyping array 374 2021-08-27 33649182 Penova M 2021-03-01 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/33649182 Genome wide association study of HTLV-1-associated myelopathy/tropical spastic paraparesis in the Japanese population. HTLV-1 associated myelopathy 731 Japanese ancestry cases, 846 Japanese ancestry controls NA Illumina [126394] 8 tropical spastic paraparesis http://www.ebi.ac.uk/efo/EFO_0007527 GCST90026455 Genome-wide genotyping array 1577 2021-11-02 34231218 McDonough CW 2021-07-07 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/34231218 Adverse Cardiovascular Outcomes and Antihypertensive treatment: A Genome-Wide Interaction Meta-Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies (ICAPS). Adverse cardiovascular outcome x beta blockers interaction in hypertension 9,195 European ancestry individuals NA Affymetrix, Illumina [6400000] (imputed) 10 response to beta blocker, cardiovascular event measurement http://www.ebi.ac.uk/efo/EFO_0007766, http://www.ebi.ac.uk/efo/EFO_0006919 GCST90026457 Genome-wide genotyping array 9195 2021-11-02 34231218 McDonough CW 2021-07-07 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/34231218 Adverse Cardiovascular Outcomes and Antihypertensive treatment: A Genome-Wide Interaction Meta-Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies (ICAPS). Adverse cardiovascular outcome x calcium channel blockers interaction in hypertension 10,511 European ancestry individuals NA Affymetrix, Illumina [6400000] (imputed) 3 response to calcium channel blocker, cardiovascular event measurement http://www.ebi.ac.uk/efo/EFO_0007767, http://www.ebi.ac.uk/efo/EFO_0006919 GCST90026458 Genome-wide genotyping array 10511 2021-11-02 34231218 McDonough CW 2021-07-07 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/34231218 Adverse Cardiovascular Outcomes and Antihypertensive treatment: A Genome-Wide Interaction Meta-Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies (ICAPS). Adverse cardiovascular outcome x ACE inhibitors/ARBs interaction in hypertension 2,559 European ancestry individuals NA Affymetrix, Illumina [6400000] (imputed) 3 response to angiotensin-converting enzyme inhibitor, cardiovascular event measurement, response to angiotensin receptor blocker http://www.ebi.ac.uk/efo/EFO_0005325, http://www.ebi.ac.uk/efo/EFO_0006919, http://www.ebi.ac.uk/efo/EFO_0010735 GCST90026459 Genome-wide genotyping array 2559 2021-11-02 34231218 McDonough CW 2021-07-07 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/34231218 Adverse Cardiovascular Outcomes and Antihypertensive treatment: A Genome-Wide Interaction Meta-Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies (ICAPS). Adverse cardiovascular outcome x thiazide/thiazide-like diuretics interaction in hypertension 3,516 European ancestry individuals NA Affymetrix, Illumina [6400000] (imputed) 1 response to diuretic, cardiovascular event measurement http://purl.obolibrary.org/obo/GO_0036270, http://www.ebi.ac.uk/efo/EFO_0006919 GCST90026460 Genome-wide genotyping array 3516 2021-08-24 33542050 Namkoong H 2021-02-04 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/33542050 Genome-wide association study in patients with pulmonary Mycobacterium avium complex disease. Pulmonary mycobacterium avium complex disease 475 Japanese ancestry cases, 417 Japanese ancestry controls 1,313 East Asian ancestry cases, 2,440 East Asian ancestry controls, 276 European ancestry cases, 206 European ancestry controls Affymetrix [5876247] (imputed) 1 Mycobacterium avium complex disease http://www.ebi.ac.uk/efo/EFO_0007386 GCST90026449 Genome-wide genotyping array 892 2021-10-08 34069769 Al-Sarraj Y 2021-05-18 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/34069769 Family-Based Genome-Wide Association Study of Autism Spectrum Disorder in Middle Eastern Families. Autism spectrum disorder 487 Middle Eastern ancestry individuals from 171 families NA Illumina [516320] 7 autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0003756 GCST012466 Genome-wide genotyping array 658 2021-06-21 34002480 Damotte V 2021-05-18 Alzheimers Dement www.ncbi.nlm.nih.gov/pubmed/34002480 Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants. Plasma amyloid beta peptide concentrations (ABx-40) 12,369 European ancestry non-demented individuals NA Affymetrix, Illumina [NR] (imputed) 1 plasma beta-amyloid 1-40 measurement http://www.ebi.ac.uk/efo/EFO_0005659 GCST011942 Genome-wide genotyping array 12369 2021-06-21 34002480 Damotte V 2021-05-18 Alzheimers Dement www.ncbi.nlm.nih.gov/pubmed/34002480 Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants. Plasma amyloid beta peptide concentrations (ABx-42) 12,369 European ancestry non-demented individuals NA Affymetrix, Illumina [NR] (imputed) 1 plasma beta-amyloid 1-42 measurement http://www.ebi.ac.uk/efo/EFO_0005660 GCST011941 Genome-wide genotyping array 12369 2021-06-21 34002480 Damotte V 2021-05-18 Alzheimers Dement www.ncbi.nlm.nih.gov/pubmed/34002480 Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants. Plasma amyloid beta peptide concentration (ABx-40/ABx-42 ratio) 12,369 European ancestry non-demented individuals NA Affymetrix, Illumina [NR] (imputed) 1 plasma beta-amyloid 1-40:1-42 ratio measurement http://www.ebi.ac.uk/efo/EFO_0600016 GCST011943 Genome-wide genotyping array 12369 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Body fat distribution (trunk fat ratio) 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 body fat distribution http://www.ebi.ac.uk/efo/EFO_0004341 GCST90044720 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Android fat/gynoid fat ratio 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 body fat distribution http://www.ebi.ac.uk/efo/EFO_0004341 GCST90044721 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Trunk fat/peripheral fat ratio 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 body fat distribution http://www.ebi.ac.uk/efo/EFO_0004341 GCST90044722 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Android total mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 bone measurement, fat body mass, lean body mass http://www.ebi.ac.uk/efo/EFO_0004512, http://www.ebi.ac.uk/efo/EFO_0005409, http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044723 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Gynoid total mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 bone measurement, fat body mass, lean body mass http://www.ebi.ac.uk/efo/EFO_0004512, http://www.ebi.ac.uk/efo/EFO_0005409, http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044724 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Arm total mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 2 bone measurement, fat body mass, lean body mass http://www.ebi.ac.uk/efo/EFO_0004512, http://www.ebi.ac.uk/efo/EFO_0005409, http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044725 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Leg total mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 2 bone measurement, fat body mass, lean body mass http://www.ebi.ac.uk/efo/EFO_0004512, http://www.ebi.ac.uk/efo/EFO_0005409, http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044726 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Trunk total mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 bone measurement, fat body mass, lean body mass http://www.ebi.ac.uk/efo/EFO_0004512, http://www.ebi.ac.uk/efo/EFO_0005409, http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044727 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Total bone mineral content 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 bone mineral content measurement http://www.ebi.ac.uk/efo/EFO_0007621 GCST90044728 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Total fat mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST90044729 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Total lean mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044730 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Total mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 bone measurement, fat body mass, lean body mass http://www.ebi.ac.uk/efo/EFO_0004512, http://www.ebi.ac.uk/efo/EFO_0005409, http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044731 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Android fat mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST90044732 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Gynoid fat mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 2 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST90044733 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Arm fat mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST90044734 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Leg fat mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 3 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST90044735 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Trunk fat mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST90044736 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Visceral adipose tissue mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 visceral adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004765 GCST90044737 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Visceral adipose tissue volume 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 visceral adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004765 GCST90044738 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Android lean mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044739 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Gynoid lean mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 1 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044740 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Arm lean mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044741 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Leg lean mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044742 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Trunk lean mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044743 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Android bone mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 1 bone measurement http://www.ebi.ac.uk/efo/EFO_0004512 GCST90044744 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Gynoid bone mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 1 bone measurement http://www.ebi.ac.uk/efo/EFO_0004512 GCST90044745 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Arm bone mineral content 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 1 bone mineral content measurement http://www.ebi.ac.uk/efo/EFO_0007621 GCST90044746 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Leg bone mineral content 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 bone mineral content measurement http://www.ebi.ac.uk/efo/EFO_0007621 GCST90044747 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Trunk bone mineral content 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 bone mineral content measurement http://www.ebi.ac.uk/efo/EFO_0007621 GCST90044748 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Body fat distribution (arm fat ratio) 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 body fat distribution http://www.ebi.ac.uk/efo/EFO_0004341 GCST90044749 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Body fat distribution (leg fat ratio) 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 body fat distribution http://www.ebi.ac.uk/efo/EFO_0004341 GCST90044750 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Body fat distribution (trunk fat ratio) 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 1 body fat distribution http://www.ebi.ac.uk/efo/EFO_0004341 GCST90044751 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Android fat/gynoid fat ratio 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 1 body fat distribution http://www.ebi.ac.uk/efo/EFO_0004341 GCST90044752 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Trunk fat/peripheral fat ratio 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 body fat distribution http://www.ebi.ac.uk/efo/EFO_0004341 GCST90044753 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Android total mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 bone measurement, fat body mass, lean body mass http://www.ebi.ac.uk/efo/EFO_0004512, http://www.ebi.ac.uk/efo/EFO_0005409, http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044754 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Gynoid total mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 bone measurement, fat body mass, lean body mass http://www.ebi.ac.uk/efo/EFO_0004512, http://www.ebi.ac.uk/efo/EFO_0005409, http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044755 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Arm total mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 bone measurement, fat body mass, lean body mass http://www.ebi.ac.uk/efo/EFO_0004512, http://www.ebi.ac.uk/efo/EFO_0005409, http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044756 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Leg total mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 bone measurement, fat body mass, lean body mass http://www.ebi.ac.uk/efo/EFO_0004512, http://www.ebi.ac.uk/efo/EFO_0005409, http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044757 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Trunk total mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 bone measurement, fat body mass, lean body mass http://www.ebi.ac.uk/efo/EFO_0004512, http://www.ebi.ac.uk/efo/EFO_0005409, http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044758 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Total bone mineral content 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 bone mineral content measurement http://www.ebi.ac.uk/efo/EFO_0007621 GCST90044759 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Total fat mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST90044760 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Total lean mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044761 Genome-wide genotyping array 2109 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Total mass 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 bone measurement, fat body mass, lean body mass http://www.ebi.ac.uk/efo/EFO_0004512, http://www.ebi.ac.uk/efo/EFO_0005409, http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044762 Genome-wide genotyping array 2109 2021-09-08 34431594 Atkins JL 2021-08-25 Aging Cell www.ncbi.nlm.nih.gov/pubmed/34431594 A genome-wide association study of the frailty index highlights brain pathways in ageing. Frailty index 175,226 European ancestry individuals NA Affymetrix, Illumina [7666890] (imputed) 14 frailty measurement http://www.ebi.ac.uk/efo/EFO_0009885 GCST90020053 Genome-wide genotyping array 175226 2021-11-12 33713409 Chenoweth MJ 2021-03-13 Nicotine Tob Res www.ncbi.nlm.nih.gov/pubmed/33713409 A genome-wide association study of nausea incidence in varenicline-treated cigarette smokers. Nausea incidence in varenicline-treated smokers 57 European ancestry cases, 132 European ancestry controls NA Illumina [NR] (imputed) 11 Nausea http://purl.obolibrary.org/obo/HP_0002018 GCST90027236 Genome-wide genotyping array 189 2021-11-01 34469433 Ashvetiya T 2021-09-01 PLoS One www.ncbi.nlm.nih.gov/pubmed/34469433 Identification of novel genetic susceptibility loci for thoracic and abdominal aortic aneurysms via genome-wide association study using the UK Biobank Cohort. Abdominal aortic aneurysm 1,363 European, Indian, Caribbean, African ancestry cases, 27,260 European, Indian, Caribbean, African ancestry controls NA NR [NR] (imputed) 19 Abdominal Aortic Aneurysm http://www.ebi.ac.uk/efo/EFO_0004214 GCST90038468 Genome-wide genotyping array 28623 2021-11-01 34469433 Ashvetiya T 2021-09-01 PLoS One www.ncbi.nlm.nih.gov/pubmed/34469433 Identification of novel genetic susceptibility loci for thoracic and abdominal aortic aneurysms via genome-wide association study using the UK Biobank Cohort. Thoracic aortic aneurysms 435 European, Indian, Caribbean, African ancestry cases, 8,700 European, Indian, Caribbean, African ancestry ancestry controls NA NR [NR] (imputed) 16 thoracic aortic aneurysm http://www.ebi.ac.uk/efo/EFO_0004282 GCST90038469 Genome-wide genotyping array 9135 2021-10-07 34512620 Matzaraki V 2021-08-26 Front Immunol www.ncbi.nlm.nih.gov/pubmed/34512620 Inflammatory Protein Profiles in Plasma of Candidaemia Patients and the Contribution of Host Genetics to Their Variability. Candida albicans stimulated MCP-2 levels 378 European ancestry individuals NA Illumina [NR] (imputed) 1 monocyte chemotactic protein-2 measurement http://www.ebi.ac.uk/efo/EFO_0010789 GCST90038445 Genome-wide genotyping array 378 2021-10-07 34512620 Matzaraki V 2021-08-26 Front Immunol www.ncbi.nlm.nih.gov/pubmed/34512620 Inflammatory Protein Profiles in Plasma of Candidaemia Patients and the Contribution of Host Genetics to Their Variability. Candida albicans stimulated CCL3 levels 378 European ancestry individuals NA Illumina [NR] (imputed) 2 CCL3 measurement http://www.ebi.ac.uk/efo/EFO_0010770 GCST90038446 Genome-wide genotyping array 378 2021-10-07 34512620 Matzaraki V 2021-08-26 Front Immunol www.ncbi.nlm.nih.gov/pubmed/34512620 Inflammatory Protein Profiles in Plasma of Candidaemia Patients and the Contribution of Host Genetics to Their Variability. Candida albicans stimulated MMP-1 levels 378 European ancestry individuals NA Illumina [NR] (imputed) 1 matrix metalloproteinase 1 measurement http://www.ebi.ac.uk/efo/EFO_0010588 GCST90038447 Genome-wide genotyping array 378 2021-10-07 34512620 Matzaraki V 2021-08-26 Front Immunol www.ncbi.nlm.nih.gov/pubmed/34512620 Inflammatory Protein Profiles in Plasma of Candidaemia Patients and the Contribution of Host Genetics to Their Variability. Candida albicans stimulated IL-8 levels 378 European ancestry individuals NA Illumina [NR] (imputed) 1 interleukin 8 measurement http://www.ebi.ac.uk/efo/EFO_0008191 GCST90038448 Genome-wide genotyping array 378 2021-10-07 34512620 Matzaraki V 2021-08-26 Front Immunol www.ncbi.nlm.nih.gov/pubmed/34512620 Inflammatory Protein Profiles in Plasma of Candidaemia Patients and the Contribution of Host Genetics to Their Variability. Survival in candidemia 52 European ancestry cases, 104 European ancestry controls NA Illumina [5450489] (imputed) 0 survival time, Candidemia http://www.ebi.ac.uk/efo/EFO_0000714, http://www.ebi.ac.uk/efo/EFO_1001282 GCST90038449 Genome-wide genotyping array 156 2021-06-01 33179336 Syreeni A 2020-11-11 J Intern Med www.ncbi.nlm.nih.gov/pubmed/33179336 Genome-wide search for genes affecting the age at diagnosis of type 1 diabetes. Type 1 diabetes (age at diagnosis) 12,539 European ancestry individuals NA Affymetrix, Illumina [7374092] (imputed) 39 type I diabetes mellitus, age at diagnosis http://www.ebi.ac.uk/efo/EFO_0001359, http://www.ebi.ac.uk/efo/EFO_0004918 GCST011773 Genome-wide genotyping array 12539 2021-07-02 34038024 Kuo CL 2021-05-26 Aging Cell www.ncbi.nlm.nih.gov/pubmed/34038024 Genetic associations for two biological age measures point to distinct aging phenotypes. Biological age (BioAge) 98,446 European ancestry individuals 1,782 European ancestry individuals Affymetrix [16446666] (imputed) 0 aging http://purl.obolibrary.org/obo/GO_0007568 GCST011992 Genome-wide genotyping array 98446 2021-07-02 34038024 Kuo CL 2021-05-26 Aging Cell www.ncbi.nlm.nih.gov/pubmed/34038024 Genetic associations for two biological age measures point to distinct aging phenotypes. Biological age (PhenoAge) 107,460 European ancestry individuals 5,572 European ancestry individuals Affymetrix [16446666] (imputed) 0 aging http://purl.obolibrary.org/obo/GO_0007568 GCST011993 Genome-wide genotyping array 107460 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Two-hour glucose 1,431 African American individuals NA Affymetrix, Illumina [22935934] (imputed) 0 glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0004307 GCST90002225 Genome-wide genotyping array, Targeted genotyping array [Genome-wide genotyping array|Metabochip] 1431 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Two-hour glucose 8,509 East Asian ancestry individuals NA Affymetrix [9187953] (imputed) 1 glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0004307 GCST90002226 Genome-wide genotyping array 8509 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Two-hour glucose 63,396 European ancestry individuals NA Affymetrix, Illumina [30098705] (imputed) 17 glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0004307 GCST90002227 Genome-wide genotyping array, Targeted genotyping array [Genome-wide genotyping array|Metabochip] 63396 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Two-hour glucose 12,578 Hispanic individuals NA Illumina [24662309] (imputed) 4 glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0004307 GCST90002228 Genome-wide genotyping array 12578 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Two-hour glucose 1,431 African American individuals, 8,509 East Asian ancestry individuals, 63,396 European ancestry individuals, 12,578 Hispanic individuals NA Affymetrix, Illumina [38654120] (imputed) 0 glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0004307 GCST90002229 Genome-wide genotyping array, Targeted genotyping array [Genome-wide genotyping array|Metabochip] 85914 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Fasting glucose 16,579 African American individuals NA Affymetrix, Illumina [27843817] (imputed) 11 glucose measurement http://www.ebi.ac.uk/efo/EFO_0004468 GCST90002230 Genome-wide genotyping array, Targeted genotyping array [Genome-wide genotyping array|Metabochip] 16579 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Fasting glucose 35,619 East Asian ancestry individuals NA Affymetrix, Illumina [15438438] (imputed) 15 glucose measurement http://www.ebi.ac.uk/efo/EFO_0004468 GCST90002231 Genome-wide genotyping array, Targeted genotyping array [Genome-wide genotyping array|Metabochip] 35619 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Fasting glucose 200,622 European ancestry individuals NA Affymetrix, Illumina [34064007] (imputed) 92 glucose measurement http://www.ebi.ac.uk/efo/EFO_0004468 GCST90002232 Genome-wide genotyping array, Targeted genotyping array [Genome-wide genotyping array|Metabochip] 200622 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Fasting glucose 19,247 Hispanic individuals NA Affymetrix, Illumina [28177426] (imputed) 13 glucose measurement http://www.ebi.ac.uk/efo/EFO_0004468 GCST90002233 Genome-wide genotyping array, Targeted genotyping array [Genome-wide genotyping array|Metabochip] 19247 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Fasting glucose 9,343 South Asian ancestry individuals NA Illumina, Perlegen [20274841] (imputed) 9 glucose measurement http://www.ebi.ac.uk/efo/EFO_0004468 GCST90002234 Genome-wide genotyping array 9343 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Fasting glucose 16,579 African American individuals, 35,619 East Asian ancestry individuals, 20,0622 European ancestry individuals, 19,247 Hispanic individuals, 9,343 South Asian ancestry individuals NA Affymetrix, Illumina, Perlegen [42673998] (imputed) 0 glucose measurement http://www.ebi.ac.uk/efo/EFO_0004468 GCST90002235 Genome-wide genotyping array, Targeted genotyping array [Genome-wide genotyping array|Metabochip] 281410 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Fasting insulin 8,101 African American individuals NA Affymetrix, Illumina [26320006] (imputed) 2 insulin measurement http://www.ebi.ac.uk/efo/EFO_0004467 GCST90002236 Genome-wide genotyping array, Targeted genotyping array [Genome-wide genotyping array|Metabochip] 8101 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Fasting insulin 29,792 East Asian ancestry individuals NA Affymetrix, Illumina [14733249] (imputed) 1 insulin measurement http://www.ebi.ac.uk/efo/EFO_0004467 GCST90002237 Genome-wide genotyping array, Targeted genotyping array [Genome-wide genotyping array|Metabochip] 29792 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Fasting insulin 151,013 European ancestry individuals NA Affymetrix, Illumina [32635793] (imputed) 54 insulin measurement http://www.ebi.ac.uk/efo/EFO_0004467 GCST90002238 Genome-wide genotyping array, Targeted genotyping array [Genome-wide genotyping array|Metabochip] 151013 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Fasting insulin 16,386 Hispanic individuals NA Affymetrix, Illumina [26195808] (imputed) 8 insulin measurement http://www.ebi.ac.uk/efo/EFO_0004467 GCST90002239 Genome-wide genotyping array, Targeted genotyping array [Genome-wide genotyping array|Metabochip] 16386 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Fasting insulin 8,353 South Asian ancestry individuals NA Illumina, Perlegen [20092343] (imputed) 0 insulin measurement http://www.ebi.ac.uk/efo/EFO_0004467 GCST90002240 Genome-wide genotyping array 8353 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Fasting insulin 8,101 African American individuals, 29,792 East Asian ancestry individuals, 151,013 European ancestry individuals, 16,386 Hispanic individuals, 8,353 South Asian ancestry individuals NA Affymetrix, Illumina, Perlegen [41471552] (imputed) 0 insulin measurement http://www.ebi.ac.uk/efo/EFO_0004467 GCST90002241 Genome-wide genotyping array, Targeted genotyping array [Genome-wide genotyping array|Metabochip] 213645 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Glycated hemoglobin levels 6,647 African American individuals NA Affymetrix, Illumina [26614666] (imputed) 5 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST90002242 Genome-wide genotyping array, Targeted genotyping array [Genome-wide genotyping array|Metabochip] 6647 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Glycated hemoglobin levels 33,307 East Asian ancestry individuals NA Affymetrix, Illumina [15728197] (imputed) 27 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST90002243 Genome-wide genotyping array, Targeted genotyping array [Genome-wide genotyping array|Metabochip] 33307 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Glycated hemoglobin levels 146,806 European ancestry individuals NA Affymetrix, Illumina [33811881] (imputed) 113 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST90002244 Genome-wide genotyping array, Targeted genotyping array [Genome-wide genotyping array|Metabochip] 146806 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Glycated hemoglobin levels 15,248 Hispanic individuals NA Affymetrix, Illumina [29199641] (imputed) 13 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST90002245 Genome-wide genotyping array, Targeted genotyping array [Genome-wide genotyping array|Metabochip] 15248 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Glycated hemoglobin levels 9,525 South Asian ancestry individuals NA Illumina, Perlegen [19922415] (imputed) 3 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST90002246 Genome-wide genotyping array 9525 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Glycated hemoglobin levels 6,647 African American individuals, 33,307 East Asian ancestry individuals, 146,806 European ancestry individuals, 15,248 Hispanic individuals, 9,525 South Asian ancestry individuals, 4,441 Sub-Saharan African ancestry individuals NA Affymetrix, Illumina, Perlegen [43540446] (imputed) 0 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST90002247 Genome-wide genotyping array, Targeted genotyping array [Genome-wide genotyping array|Metabochip] 215974 2021-06-10 34059833 Chen J 2021-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34059833 The trans-ancestral genomic architecture of glycemic traits. Glycated hemoglobin levels 4,441 Sub-Saharan African ancestry individuals NA NR [19426848] (imputed) 2 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST90002248 Genome-wide genotyping array 4441 2021-07-27 34074324 Wan JY 2021-06-01 Diabetol Metab Syndr www.ncbi.nlm.nih.gov/pubmed/34074324 Genome-wide association analysis of metabolic syndrome quantitative traits in the GENNID multiethnic family study. Weight 281 African American individuals from 73 families, 516 European ancestry individuals from 75 families, 125 Japanese American individuals from 15 families, 598 Mexican American individuals from 96 families NA Illumina [up to 13042663] (imputed) 12 body weight http://www.ebi.ac.uk/efo/EFO_0004338 GCST012053 Genome-wide genotyping array 1779 2021-07-27 34074324 Wan JY 2021-06-01 Diabetol Metab Syndr www.ncbi.nlm.nih.gov/pubmed/34074324 Genome-wide association analysis of metabolic syndrome quantitative traits in the GENNID multiethnic family study. Waist circumference 281 African American individuals from 73 families, 516 European ancestry individuals from 75 families, 125 Japanese American individuals from 15 families, 598 Mexican American individuals from 96 families NA Illumina [up to 13042663] (imputed) 9 waist circumference http://www.ebi.ac.uk/efo/EFO_0004342 GCST012052 Genome-wide genotyping array 1779 2021-07-27 34074324 Wan JY 2021-06-01 Diabetol Metab Syndr www.ncbi.nlm.nih.gov/pubmed/34074324 Genome-wide association analysis of metabolic syndrome quantitative traits in the GENNID multiethnic family study. Systolic blood pressure 281 African American individuals from 73 families, 516 European ancestry individuals from 75 families, 125 Japanese American individuals from 15 families, 598 Mexican American individuals from 96 families NA Illumina [up to 13042663] (imputed) 7 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST012051 Genome-wide genotyping array 1779 2021-07-27 34074324 Wan JY 2021-06-01 Diabetol Metab Syndr www.ncbi.nlm.nih.gov/pubmed/34074324 Genome-wide association analysis of metabolic syndrome quantitative traits in the GENNID multiethnic family study. Diastolic blood pressure 281 African American individuals from 73 families, 516 European ancestry individuals from 75 families, 125 Japanese American individuals from 15 families, 598 Mexican American individuals from 96 families NA Illumina [up to 13042663] (imputed) 3 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST012050 Genome-wide genotyping array 1779 2021-07-27 34074324 Wan JY 2021-06-01 Diabetol Metab Syndr www.ncbi.nlm.nih.gov/pubmed/34074324 Genome-wide association analysis of metabolic syndrome quantitative traits in the GENNID multiethnic family study. High density lipoprotein cholesterol levels 281 African American individuals from 73 families, 516 European ancestry individuals from 75 families, 125 Japanese American individuals from 15 families, 598 Mexican American individuals from 96 families NA Illumina [up to 13042663] (imputed) 6 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST012049 Genome-wide genotyping array 1779 2021-07-27 34074324 Wan JY 2021-06-01 Diabetol Metab Syndr www.ncbi.nlm.nih.gov/pubmed/34074324 Genome-wide association analysis of metabolic syndrome quantitative traits in the GENNID multiethnic family study. Triglyceride levels 281 African American individuals from 73 families, 516 European ancestry individuals from 75 families, 125 Japanese American individuals from 15 families, 598 Mexican American individuals from 96 families NA Illumina [up to 13042663] (imputed) 33 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST012048 Genome-wide genotyping array 1779 2021-07-27 34074324 Wan JY 2021-06-01 Diabetol Metab Syndr www.ncbi.nlm.nih.gov/pubmed/34074324 Genome-wide association analysis of metabolic syndrome quantitative traits in the GENNID multiethnic family study. Fasting glucose 281 African American individuals from 73 families, 516 European ancestry individuals from 75 families, 125 Japanese American individuals from 15 families, 598 Mexican American individuals from 96 families NA Illumina [up to 13042663] (imputed) 22 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST012047 Genome-wide genotyping array 1779 2021-07-27 34074324 Wan JY 2021-06-01 Diabetol Metab Syndr www.ncbi.nlm.nih.gov/pubmed/34074324 Genome-wide association analysis of metabolic syndrome quantitative traits in the GENNID multiethnic family study. Fasting insulin 281 African American individuals from 73 families, 516 European ancestry individuals from 75 families, 125 Japanese American individuals from 15 families, 598 Mexican American individuals from 96 families NA Illumina [up to 13042663] (imputed) 7 fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0004466 GCST012046 Genome-wide genotyping array 1779 2021-07-27 34054130 Bralten J 2021-05-30 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/34054130 Genetic underpinnings of sociability in the general population. Sociability score 342,461 European ancestry individuals NA Affymetrix [9327396] (imputed) 19 social interaction measurement http://www.ebi.ac.uk/efo/EFO_0009592 GCST012114 Genome-wide genotyping array 342461 2021-07-27 34054130 Bralten J 2021-05-30 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/34054130 Genetic underpinnings of sociability in the general population. Frequency of friend / family visits 342,461 European ancestry individuals NA Affymetrix [up to 9327396] (imputed) 1 social interaction measurement http://www.ebi.ac.uk/efo/EFO_0009592 GCST012113 Genome-wide genotyping array 342461 2021-07-27 34054130 Bralten J 2021-05-30 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/34054130 Genetic underpinnings of sociability in the general population. Attending social / leisure activities 342,461 European ancestry individuals NA Affymetrix [up to 9327396] (imputed) 1 social interaction measurement http://www.ebi.ac.uk/efo/EFO_0009592 GCST012112 Genome-wide genotyping array 342461 2021-07-27 34054130 Bralten J 2021-05-30 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/34054130 Genetic underpinnings of sociability in the general population. Worry too long after an embarrassing experience 342,461 European ancestry individuals NA Affymetrix [up to 9327396] (imputed) 9 worry measurement http://www.ebi.ac.uk/efo/EFO_0009589 GCST012111 Genome-wide genotyping array 342461 2021-07-27 34054130 Bralten J 2021-05-30 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/34054130 Genetic underpinnings of sociability in the general population. Loneliness 342,461 European ancestry individuals NA Affymetrix [up to 9327396] (imputed) 4 loneliness measurement http://www.ebi.ac.uk/efo/EFO_0007865 GCST012110 Genome-wide genotyping array 342461 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Android fat mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 1 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST90026418 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Gynoid fat mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST90026419 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Arm fat mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST90026420 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Leg fat mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST90026421 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Trunk fat mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 1 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST90026422 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Visceral adipose tissue mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 1 visceral adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004765 GCST90026423 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Visceral adipose tissue volume 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 1 visceral adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004765 GCST90026424 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Android lean mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST90026425 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Gynoid lean mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 1 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST90026426 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Arm lean mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST90026427 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Leg lean mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST90026428 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Trunk lean mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 1 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST90026429 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Android bone mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 bone measurement http://www.ebi.ac.uk/efo/EFO_0004512 GCST90026430 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Gynoid bone mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 bone measurement http://www.ebi.ac.uk/efo/EFO_0004512 GCST90026431 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Arm bone mineral content 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 bone mineral content measurement http://www.ebi.ac.uk/efo/EFO_0007621 GCST90026432 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Leg bone mineral content 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 bone mineral content measurement http://www.ebi.ac.uk/efo/EFO_0007621 GCST90026433 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Trunk bone mineral content 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 bone mineral content measurement http://www.ebi.ac.uk/efo/EFO_0007621 GCST90026434 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Body fat distribution (arm fat ratio) 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 body fat distribution http://www.ebi.ac.uk/efo/EFO_0004341 GCST90026435 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Body fat distribution (leg fat ratio) 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 body fat distribution http://www.ebi.ac.uk/efo/EFO_0004341 GCST90026436 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Body fat distribution (trunk fat ratio) 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 body fat distribution http://www.ebi.ac.uk/efo/EFO_0004341 GCST90026437 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Android fat/gynoid fat ratio 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 body fat distribution http://www.ebi.ac.uk/efo/EFO_0004341 GCST90026438 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Trunk fat/peripheral fat ratio 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 1 body fat distribution http://www.ebi.ac.uk/efo/EFO_0004341 GCST90026439 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Android total mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 1 bone measurement, fat body mass, lean body mass http://www.ebi.ac.uk/efo/EFO_0004512, http://www.ebi.ac.uk/efo/EFO_0005409, http://www.ebi.ac.uk/efo/EFO_0004995 GCST90026440 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Gynoid total mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 bone measurement, fat body mass, lean body mass http://www.ebi.ac.uk/efo/EFO_0004512, http://www.ebi.ac.uk/efo/EFO_0005409, http://www.ebi.ac.uk/efo/EFO_0004995 GCST90026441 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Arm total mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 bone measurement, fat body mass, lean body mass http://www.ebi.ac.uk/efo/EFO_0004512, http://www.ebi.ac.uk/efo/EFO_0005409, http://www.ebi.ac.uk/efo/EFO_0004995 GCST90026442 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Leg total mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 bone measurement, fat body mass, lean body mass http://www.ebi.ac.uk/efo/EFO_0004512, http://www.ebi.ac.uk/efo/EFO_0005409, http://www.ebi.ac.uk/efo/EFO_0004995 GCST90026443 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Trunk total mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 1 bone measurement, fat body mass, lean body mass http://www.ebi.ac.uk/efo/EFO_0004512, http://www.ebi.ac.uk/efo/EFO_0005409, http://www.ebi.ac.uk/efo/EFO_0004995 GCST90026444 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Total bone mineral content 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 bone mineral content measurement http://www.ebi.ac.uk/efo/EFO_0007621 GCST90026445 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Total fat mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST90026446 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Total lean mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST90026447 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Total mass 2,294 White British ancestry female individuals, 2,109 White British ancestry male individuals NA NR [6137607] (imputed) 0 bone measurement, fat body mass, lean body mass http://www.ebi.ac.uk/efo/EFO_0004512, http://www.ebi.ac.uk/efo/EFO_0005409, http://www.ebi.ac.uk/efo/EFO_0004995 GCST90026448 Genome-wide genotyping array 4403 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Android fat mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST90044701 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Gynoid fat mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST90044702 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Arm fat mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 1 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST90044703 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Leg fat mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST90044704 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Trunk fat mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST90044705 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Visceral adipose tissue mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 visceral adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004765 GCST90044706 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Visceral adipose tissue volume 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 visceral adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004765 GCST90044707 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Android lean mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044708 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Gynoid lean mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044709 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Arm lean mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044710 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Leg lean mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 1 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044711 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Trunk lean mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST90044712 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Android bone mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 bone measurement http://www.ebi.ac.uk/efo/EFO_0004512 GCST90044713 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Gynoid bone mass 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 1 bone measurement http://www.ebi.ac.uk/efo/EFO_0004512 GCST90044714 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Arm bone mineral content 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 bone mineral content measurement http://www.ebi.ac.uk/efo/EFO_0007621 GCST90044715 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Leg bone mineral content 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 bone mineral content measurement http://www.ebi.ac.uk/efo/EFO_0007621 GCST90044716 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Trunk bone mineral content 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 1 bone mineral content measurement http://www.ebi.ac.uk/efo/EFO_0007621 GCST90044717 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Body fat distribution (arm fat ratio) 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 body fat distribution http://www.ebi.ac.uk/efo/EFO_0004341 GCST90044718 Genome-wide genotyping array 2294 2021-10-08 34239500 Livingstone KM 2021-06-22 Front Endocrinol (Lausanne) www.ncbi.nlm.nih.gov/pubmed/34239500 Discovery Genome-Wide Association Study of Body Composition in 4,386 Adults From the UK Biobank's Pilot Imaging Enhancement Study. Body fat distribution (leg fat ratio) 2,294 White British ancestry female individuals NA NR [6137607] (imputed) 0 body fat distribution http://www.ebi.ac.uk/efo/EFO_0004341 GCST90044719 Genome-wide genotyping array 2294 2021-11-02 34475377 Reus LM 2021-09-02 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/34475377 Genome-wide association study of frontotemporal dementia identifies a C9ORF72 haplotype with a median of 12-G4C2 repeats that predisposes to pathological repeat expansions. Frontotemporal dementia 354 Dutch ancestry cases, 4,209 Dutch ancestry controls 281 Dutch ancestry cases, 618 Dutch ancestry controls Illumina [39131578] (imputed) 2 Frontotemporal dementia http://www.orpha.net/ORDO/Orphanet_282 GCST90038470 Genome-wide genotyping array 4563 2021-10-06 30255811 Restrepo NA 2018-09-14 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/30255811 Local genetic ancestry in CDKN2B-AS1 is associated with primary open-angle glaucoma in an African American cohort extracted from de-identified electronic health records. Glaucoma (primary open-angle) 138 African American cases, 1,376 African American controls NA Illumina [Metabochip] 0 open-angle glaucoma http://www.ebi.ac.uk/efo/EFO_0004190 GCST012451 Targeted genotyping array [Metabochip] 1514 2021-06-07 33975060 Zhu Y 2021-05-07 Eur J Cancer www.ncbi.nlm.nih.gov/pubmed/33975060 A genetic variant conferred high expression of CAV2 promotes pancreatic cancer progression and associates with poor prognosis. Pancreatic ductal adenocarcinoma 518 Han Chinese ancestry cases 552 Han Chinese ancestry cases Illumina [Exome array] 1 pancreatic carcinoma http://www.ebi.ac.uk/efo/EFO_0002618 GCST011817 Exome genotyping array [Exome array] 518 2021-08-16 32675224 Thorball CW 2020-07-16 Haematologica www.ncbi.nlm.nih.gov/pubmed/32675224 Genetic variation near CXCL12 is associated with susceptibility to HIV-related non-Hodgkin lymphoma. Non-hodgkin's lymphoma in HIV infection 278 European ancestry cases, 1,924 European ancestry controls NA Illumina [6200000] (imputed) 1 non-Hodgkins lymphoma http://www.ebi.ac.uk/efo/EFO_0005952 GCST90025870 Genome-wide genotyping array 2202 2021-10-27 34648798 Seo JY 2021-10-11 J Invest Dermatol www.ncbi.nlm.nih.gov/pubmed/34648798 Genome-wide association study identifies multiple genetic loci for skin color in Korean women. Facial skin colour (CIELAB index L* value) 11,079 Korean ancestry individuals 5,940 Korean ancestry individuals Illumina [5032876] (imputed) 3 facial pigmentation measurement http://www.ebi.ac.uk/efo/EFO_0006942 GCST90020054 Genome-wide genotyping array 11079 2021-10-27 34648798 Seo JY 2021-10-11 J Invest Dermatol www.ncbi.nlm.nih.gov/pubmed/34648798 Genome-wide association study identifies multiple genetic loci for skin color in Korean women. Facial skin colour (CIELAB index a* value) 11,079 Korean ancestry individuals 5,940 Korean ancestry individuals Illumina [5032876] (imputed) 0 facial pigmentation measurement http://www.ebi.ac.uk/efo/EFO_0006942 GCST90020055 Genome-wide genotyping array 11079 2021-10-27 34648798 Seo JY 2021-10-11 J Invest Dermatol www.ncbi.nlm.nih.gov/pubmed/34648798 Genome-wide association study identifies multiple genetic loci for skin color in Korean women. Facial skin colour (CIELAB index b* value) 11,079 Korean ancestry individuals 5,940 Korean ancestry individuals Illumina [5032876] (imputed) 5 facial pigmentation measurement http://www.ebi.ac.uk/efo/EFO_0006942 GCST90020056 Genome-wide genotyping array 11079 2021-11-02 34446935 Karlsson Linner R 2021-08-26 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/34446935 Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction. Externalizing behaviour (multivariate analysis) up to 53,293 European ancestry Attention-deficit/hyperactivity disorder individuals, up to 164,684 European ancestry problematic alcohol use individuals, up to 186,875 European ancestry lifetime cannabis use individuals, up to 357,187 European ancestry individuals measuring reverse-coded age at first sexual intercourse, up to 336,121 European ancestry individuals measuring number of sexual partners, up to 426,379 European ancestry individuals measuring general risk tolerance, up to 1,251,809 European ancestry individuals measuring lifetime smoking initiation NA NR [NR] (imputed) 579 attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement http://www.ebi.ac.uk/efo/EFO_0003888, http://purl.obolibrary.org/obo/MONDO_0002491, http://www.ebi.ac.uk/efo/EFO_0007052 GCST90061435 Genome-wide genotyping array 2776348 2021-10-18 34050765 Zhang L 2021-05-29 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/34050765 Joint genome-wide association analyses identified 49 novel loci for age at natural menopause. Age at menopause 181,219 European ancestry individuals NA Illumina [2398641] (imputed) 51 age at menopause http://www.ebi.ac.uk/efo/EFO_0004704 GCST90026597 Genome-wide genotyping array 181219 2021-10-18 34050765 Zhang L 2021-05-29 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/34050765 Joint genome-wide association analyses identified 49 novel loci for age at natural menopause. Age at menopause 181,219 European ancestry individuals, 43,861 East Asian ancestry individuals NA Illumina [2093892] (imputed) 46 age at menopause http://www.ebi.ac.uk/efo/EFO_0004704 GCST90026598 Genome-wide genotyping array 225080 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. ADHD vs anorexia nervosa (ordinary least squares (OLS)) 19,099 ADHD cases, 16,992 anorexia nervosa cases NA NR [5496413] (imputed) 4 anorexia nervosa, attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0004215, http://www.ebi.ac.uk/efo/EFO_0003888 GCST90016595 Genome-wide genotyping array 36091 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. ADHD vs autism spectrum disorder (ordinary least squares (OLS)) 19,099 ADHD cases, 18,381 autism spectrum disorder cases NA NR [5798030] (imputed) 1 attention deficit hyperactivity disorder, autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0003756 GCST90016596 Genome-wide genotyping array 37480 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. ADHD vs obsessive compulsive disorder (ordinary least squares (OLS)) 19,099 ADHD cases, 2,688 OCD cases NA NR [5627061] (imputed) 2 obsessive-compulsive disorder, attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0004242, http://www.ebi.ac.uk/efo/EFO_0003888 GCST90016597 Genome-wide genotyping array 21787 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. ADHD vs Tourette's syndrome and other tic disorders (ordinary least squares (OLS)) 19,099 ADHD cases, 4,819 Tourette's syndrome cases NA NR [5616739] (imputed) 2 attention deficit hyperactivity disorder, Tourette syndrome http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0004895 GCST90016598 Genome-wide genotyping array 23918 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Anorexia nervosa vs autism spectrum disorder (ordinary least squares (OLS)) 16,992 anorexia nervosa cases, 18,381 autism spectrum disorder cases NA NR [5647804] (imputed) 1 anorexia nervosa, autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0004215, http://www.ebi.ac.uk/efo/EFO_0003756 GCST90016599 Genome-wide genotyping array 35373 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Anorexia nervosa vs obsessive compulsive disorder (ordinary least squares (OLS)) 16,992 anorexia nervosa cases, 2,688 OCD cases NA NR [5520002] (imputed) 0 anorexia nervosa, obsessive-compulsive disorder http://www.ebi.ac.uk/efo/EFO_0004215, http://www.ebi.ac.uk/efo/EFO_0004242 GCST90016600 Genome-wide genotyping array 19680 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Anorexia nervosa vs Tourette's syndrome and other tic disorders (ordinary least squares (OLS)) 16,992 anorexia nervosa cases, 4,819 Tourette's syndrome cases NA NR [5508374] (imputed) 2 anorexia nervosa, Tourette syndrome http://www.ebi.ac.uk/efo/EFO_0004215, http://www.ebi.ac.uk/efo/EFO_0004895 GCST90016601 Genome-wide genotyping array 21811 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Autism spectrum disorder vs obsessive compulsive disorder (ordinary least squares (OLS)) 18,381 autism spectrum disorder cases, 2,688 OCD cases NA NR [6144458] (imputed) 1 obsessive-compulsive disorder, autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0004242, http://www.ebi.ac.uk/efo/EFO_0003756 GCST90016602 Genome-wide genotyping array 21069 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Autism spectrum disorder vs Tourette's syndrome and other tic disorders (ordinary least squares (OLS)) 18,381 autism spectrum disorder cases, 4,819 Tourette's syndrome cases NA NR [6126055] (imputed) 1 Tourette syndrome, autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0004895, http://www.ebi.ac.uk/efo/EFO_0003756 GCST90016603 Genome-wide genotyping array 23200 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Bipolar disorder vs ADHD (ordinary least squares (OLS)) 20,352 bipolar disorder cases, 19,099 ADHD cases NA NR [5637374] (imputed) 8 attention deficit hyperactivity disorder, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0000289 GCST90016604 Genome-wide genotyping array 39451 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Bipolar disorder vs anorexia nervosa (ordinary least squares (OLS)) 20,352 bipolar disorder cases, 16,992 anorexia nervosa cases NA NR [5569514] (imputed) 5 anorexia nervosa, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0004215, http://www.ebi.ac.uk/efo/EFO_0000289 GCST90016605 Genome-wide genotyping array 37344 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Bipolar disorder vs autism spectrum disorder (ordinary least squares (OLS)) 20,352 bipolar disorder cases, 18,381 autism spectrum disorder cases NA NR [6135876] (imputed) 3 autism spectrum disorder, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003756, http://www.ebi.ac.uk/efo/EFO_0000289 GCST90016606 Genome-wide genotyping array 38733 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Bipolar disorder vs major depressive disorder (ordinary least squares (OLS)) 20,352 bipolar disorder cases, 170,756 major depressive disorder cases NA NR [6265453] (imputed) 10 unipolar depression, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000289 GCST90016607 Genome-wide genotyping array 191108 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Bipolar disorder vs obsessive compulsive disorder (ordinary least squares (OLS)) 20,352 bipolar disorder cases, 2,688 OCD cases NA NR [6311569] (imputed) 1 obsessive-compulsive disorder, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0004242, http://www.ebi.ac.uk/efo/EFO_0000289 GCST90016608 Genome-wide genotyping array 23040 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Bipolar disorder vs Tourette's syndrome and other tic disorders (ordinary least squares (OLS)) 20,352 bipolar disorder cases, 4,819 Tourette's syndrome cases NA NR [6254473] (imputed) 5 Tourette syndrome, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0004895, http://www.ebi.ac.uk/efo/EFO_0000289 GCST90016609 Genome-wide genotyping array 25171 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Crohn's disease vs rheumatoid arthritis (ordinary least squares (OLS)) 5,956 Crohn's disease cases, 8,875 rheumatoid arthritis cases 14,594 Crohn's disease cases, 5,486 rheumatoid arthritis cases NR [5890016] (imputed) 24 rheumatoid arthritis, Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0000384 GCST90016610 Genome-wide genotyping array 14831 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Crohn's disease vs ulcerative colitis (ordinary least squares (OLS)) 5,956 Crohn's disease cases, 6,968 ulcerative colitis cases 14,594 Crohn's disease cases, 10,679 ulcerative colitis cases NR [6490614] (imputed) 8 ulcerative colitis, Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000729, http://www.ebi.ac.uk/efo/EFO_0000384 GCST90016611 Genome-wide genotyping array 12924 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Major depressive disorder vs ADHD (ordinary least squares (OLS)) 170,756 MDD cases, 19,099 ADHD cases NA NR [5568121] (imputed) 9 attention deficit hyperactivity disorder, unipolar depression http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0003761 GCST90016612 Genome-wide genotyping array 189855 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Major depressive disorder vs anorexia nervosa (ordinary least squares (OLS)) 170,756 MDD cases, 16,992 anorexia nervosa cases NA NR [5460735] (imputed) 6 anorexia nervosa, unipolar depression http://www.ebi.ac.uk/efo/EFO_0004215, http://www.ebi.ac.uk/efo/EFO_0003761 GCST90016613 Genome-wide genotyping array 187748 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Major depressive disorder vs autism spectrum disorder (ordinary least squares (OLS)) 170,756 MDD cases, 18,381 autism spectrum disorder cases NA NR [6057537] (imputed) 3 unipolar depression, autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0003756 GCST90016614 Genome-wide genotyping array 189137 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Major depressive disorder vs obsessive compulsive disorder (ordinary least squares (OLS)) 170,756 MDD cases, 2,688 OCD cases NA NR [6207788] (imputed) 0 obsessive-compulsive disorder, unipolar depression http://www.ebi.ac.uk/efo/EFO_0004242, http://www.ebi.ac.uk/efo/EFO_0003761 GCST90016615 Genome-wide genotyping array 173444 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Major depressive disorder vs Tourette's syndrome and other tic disorders (ordinary least squares (OLS)) 170,756 MDD cases, 4,819 Tourette's syndrome cases NA NR [6202472] (imputed) 0 Tourette syndrome, unipolar depression http://www.ebi.ac.uk/efo/EFO_0004895, http://www.ebi.ac.uk/efo/EFO_0003761 GCST90016616 Genome-wide genotyping array 175575 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Obsessive compulsive disorder vs Tourette's syndrome and other tic disorders (ordinary least squares (OLS)) 2,688 OCD cases, 4,819 Tourette's syndrome cases NA NR [6349486] (imputed) 1 obsessive-compulsive disorder, Tourette syndrome http://www.ebi.ac.uk/efo/EFO_0004242, http://www.ebi.ac.uk/efo/EFO_0004895 GCST90016617 Genome-wide genotyping array 7507 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Schizophrenia vs ADHD (ordinary least squares (OLS)) 40,675 schizophrenia cases, 19,099 ADHD cases NA NR [4428082] (imputed) 43 attention deficit hyperactivity disorder, schizophrenia http://www.ebi.ac.uk/efo/EFO_0003888, http://www.ebi.ac.uk/efo/EFO_0000692 GCST90016618 Genome-wide genotyping array 59774 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Schizophrenia vs anorexia nervosa (ordinary least squares (OLS)) 40,675 schizophrenia cases, 16,992 anorexia nervosa cases NA NR [4425810] (imputed) 41 anorexia nervosa, schizophrenia http://www.ebi.ac.uk/efo/EFO_0004215, http://www.ebi.ac.uk/efo/EFO_0000692 GCST90016619 Genome-wide genotyping array 57667 2021-02-20 33589841 Chia R 2021-02-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33589841 Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture. Dementia with Lewy bodies 2,591 European ancestry cases, 4,027 European ancestry controls NA NR [20137051] 0 Lewy body dementia http://www.ebi.ac.uk/efo/EFO_0006792 GCST90001390 Genome-wide sequencing 6618 2021-01-22 33097703 Surakka I 2020-10-23 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33097703 MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk. Ultradistal forearm bone mineral density 21,907 European ancestry individuals NA Illumina [11603265] (imputed) 32 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST90013422 Genome-wide genotyping array, Genome-wide sequencing 21907 2021-08-23 34378841 Garcia-Etxebarria K 2021-08-11 Neurogastroenterol Motil www.ncbi.nlm.nih.gov/pubmed/34378841 A survey of functional dyspepsia in 361,360 individuals: Phenotypic and genetic cross-disease analyses. Functional dyspepsia 10,078 European ancestry cases, 351,282 European ancestry controls 192 cases, 442 controls Affymetrix, Illumina [7347476] (imputed) 0 dyspepsia http://www.ebi.ac.uk/efo/EFO_0008533 GCST90010719 Genome-wide genotyping array 361360 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Bilirubin (z,z) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 1 bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004570 GCST90026002 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Cholesterol levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST90026003 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Lysine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 lysine measurement http://www.ebi.ac.uk/efo/EFO_0005002 GCST90026004 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Tyrosine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 tyrosine measurement http://www.ebi.ac.uk/efo/EFO_0005058 GCST90026005 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Pyroglutamine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 pyroglutamine measurement http://www.ebi.ac.uk/efo/EFO_0005408 GCST90026006 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Cortisol levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 cortisol measurement http://www.ebi.ac.uk/efo/EFO_0005843 GCST90026007 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Lactate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 lactate measurement http://www.ebi.ac.uk/efo/EFO_0007745 GCST90026008 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Sulfate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 sulfate measurement http://www.ebi.ac.uk/efo/EFO_0007864 GCST90026009 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1,5-anhydroglucitol (1,5-ag) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 1,5 anhydroglucitol measurement http://www.ebi.ac.uk/efo/EFO_0008009 GCST90026010 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Kynurenine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 kynurenine measurement http://www.ebi.ac.uk/efo/EFO_0008529 GCST90026011 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Asparagine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 asparagine measurement http://www.ebi.ac.uk/efo/EFO_0009766 GCST90026012 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Glycine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 glycine measurement http://www.ebi.ac.uk/efo/EFO_0009767 GCST90026013 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Proline levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 proline measurement http://www.ebi.ac.uk/efo/EFO_0009773 GCST90026014 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Ornithine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 ornithine measurement http://www.ebi.ac.uk/efo/EFO_0009776 GCST90026015 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Citrulline levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 citrulline measurement http://www.ebi.ac.uk/efo/EFO_0009777 GCST90026016 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Acetoacetate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 acetoacetate measurement http://www.ebi.ac.uk/efo/EFO_0010111 GCST90026017 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Sphingomyelin (d18:1/14:0, d16:1/16:0) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 sphingomyelin measurement http://www.ebi.ac.uk/efo/EFO_0010118 GCST90026018 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Sphingomyelin (d18:1/18:1, d18:2/18:0) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 sphingomyelin measurement http://www.ebi.ac.uk/efo/EFO_0010118 GCST90026019 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Sphingomyelin (d18:1/20:0, d16:1/22:0) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 sphingomyelin measurement http://www.ebi.ac.uk/efo/EFO_0010118 GCST90026020 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Sphingomyelin (d18:1/20:1, d18:2/20:0) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 sphingomyelin measurement http://www.ebi.ac.uk/efo/EFO_0010118 GCST90026021 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Sphingomyelin (d18:1/22:1, d18:2/22:0, d16:1/24:1) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 sphingomyelin measurement http://www.ebi.ac.uk/efo/EFO_0010118 GCST90026022 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Sphingomyelin (d18:1/24:1, d18:2/24:0) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 sphingomyelin measurement http://www.ebi.ac.uk/efo/EFO_0010118 GCST90026023 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Sphingomyelin (d18:2/16:0, d18:1/16:1) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 sphingomyelin measurement http://www.ebi.ac.uk/efo/EFO_0010118 GCST90026024 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Sphingomyelin (d18:2/24:1, d18:1/24:2) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 sphingomyelin measurement http://www.ebi.ac.uk/efo/EFO_0010118 GCST90026025 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Allantoin levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 allantoin measurement http://www.ebi.ac.uk/efo/EFO_0010456 GCST90026026 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Alpha-ketoglutarate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 Alpha ketoglutarate measurement http://www.ebi.ac.uk/efo/EFO_0010457 GCST90026027 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Dimethylglycine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 dimethylglycine measurement http://www.ebi.ac.uk/efo/EFO_0010476 GCST90026028 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Glucuronate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 glucuronate measurement http://www.ebi.ac.uk/efo/EFO_0010486 GCST90026029 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Glycerol 3-phosphate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 glycerol-3-phosphate measurement http://www.ebi.ac.uk/efo/EFO_0010488 GCST90026030 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Hypoxanthine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 hypoxanthine mesurement http://www.ebi.ac.uk/efo/EFO_0010500 GCST90026031 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-indoxyl sulfate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 indoxyl sulfate measurement http://www.ebi.ac.uk/efo/EFO_0010502 GCST90026032 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Inosine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 inosine measurement http://www.ebi.ac.uk/efo/EFO_0010503 GCST90026033 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Malate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 malate measurement http://www.ebi.ac.uk/efo/EFO_0010508 GCST90026034 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Taurine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 taurine measurement http://www.ebi.ac.uk/efo/EFO_0010536 GCST90026035 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Uridine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 uridine measurement http://www.ebi.ac.uk/efo/EFO_0010546 GCST90026036 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Xanthine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 xanthine measurement http://www.ebi.ac.uk/efo/EFO_0010548 GCST90026037 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Phosphate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 phosphate measurement http://www.ebi.ac.uk/efo/EFO_0010968 GCST90026038 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-hydroxyisobutyrate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 3-hydroxyisobutyrate measurement http://www.ebi.ac.uk/efo/EFO_0010983 GCST90026039 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 5-oxoproline levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 5-oxoproline measurement http://www.ebi.ac.uk/efo/EFO_0010988 GCST90026040 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. P-cresol sulfate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 p-cresol sulfate measurement http://www.ebi.ac.uk/efo/EFO_0010998 GCST90026041 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. (N(1) + N(8))-acetylspermidine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026042 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1,2-dipalmitoyl-gpc (16:0/16:0) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026043 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-(1-enyl-palmitoyl)-2-arachidonoyl-gpc (p-16:0/20:4) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026044 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-(1-enyl-palmitoyl)-2-oleoyl-gpc (p-16:0/18:1) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026045 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-arachidonoyl-gpc (20:4n6) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026046 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-linoleoyl-gpc (18:2) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026047 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-methylhistidine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026048 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-methylnicotinamide levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026049 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-myristoyl-2-palmitoyl-gpc (14:0/16:0) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026050 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-oleoyl-gpc (18:1) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026051 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-23308 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026315 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Ethyl beta-glucopyranoside levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026316 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-23587 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026317 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-23590 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026318 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-23593 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026319 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-23639 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026320 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-23644 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026321 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-23652 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026322 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-23739 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026323 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-24228 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026324 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-24295 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026325 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-(3-amino-3-carboxypropyl)uridine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026326 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-24337 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026327 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-24431 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026328 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-24452 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026329 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-24686 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026330 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-24699 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026331 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-amino-2-piperidone levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026332 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-24813 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026333 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-24952 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026334 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-25109 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026335 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N6-methyllysine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 1 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026336 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Glucose levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 glucose measurement http://www.ebi.ac.uk/efo/EFO_0004468 GCST90025999 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Creatinine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 creatinine measurement http://www.ebi.ac.uk/efo/EFO_0004518 GCST90026000 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Urate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 urate measurement http://www.ebi.ac.uk/efo/EFO_0004531 GCST90026001 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-11795 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026290 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-12007 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026291 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-12015 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026292 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-12100 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026293 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-12101 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026294 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-12104 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026295 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Ascorbic acid 3-sulfate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026296 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-12411 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026297 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-12906 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026298 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-carboxyethylvaline levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026299 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-13728 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026300 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-14056 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026301 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-methyl-5-imidazoleacetate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026302 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-15245 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026303 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-carboxyethylphenylalanine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026304 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-15674 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026305 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N,n,n-trimethyl-alanylproline betaine (tmap) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026306 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-18887 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026307 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-19438 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026308 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-21286 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026309 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Butyrate (4:0) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026310 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-21733 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026311 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 2-o-methylascorbic acid levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026312 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. X-22162 levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026313 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 4-chlorobenzoic acid levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026314 Genome-wide genotyping array 291 2021-11-15 34309184 Kawaratani H 2021-07-26 Liver Int www.ncbi.nlm.nih.gov/pubmed/34309184 A Genome-Wide Association Study Identifying SVEP1 Variant as a Predictor of Response to Tolvaptan for Cirrhotic Ascites. Response to tolvaptan in hepatic ascites (body weight gain) 25 Japanese ancestry non-responder cases with increase of body weight, 156 Japanese ancestry responder controls with >1.5 kg decrease of body weight 55 Japanese ancestry non-responder cases with increase of body weight, 177 Japanese ancestry responder controls with >1.5 kg decrease of body weight Affymetrix [5420892] (imputed) 3 body weight gain http://www.ebi.ac.uk/efo/EFO_0004566 GCST90027078 Genome-wide genotyping array 187 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-palmitoyl-2-arachidonoyl-gpc (16:0/20:4n6) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026052 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-palmitoyl-2-docosahexaenoyl-gpc (16:0/22:6) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026053 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-palmitoyl-2-linoleoyl-gpc (16:0/18:2) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026054 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-palmitoyl-2-oleoyl-gpc (16:0/18:1) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026055 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-palmitoyl-2-palmitoleoyl-gpc (16:0/16:1) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026056 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-palmitoyl-2-stearoyl-gpc (16:0/18:0) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026057 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-palmitoyl-2-stearoyl-gpc (16:0/18:0) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026058 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-ribosyl-imidazoleacetate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 1 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026059 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-stearoyl-2-arachidonoyl-gpc (18:0/20:4) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026060 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-stearoyl-2-docosahexaenoyl-gpc (18:0/22:6) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026061 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-stearoyl-2-linoleoyl-gpc (18:0/18:2) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026062 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-stearoyl-2-oleoyl-gpc (18:0/18:1) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026063 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 1-stearoyl-gpc (18:0) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026064 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 2'-deoxyuridine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026065 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 2'-o-methylcytidine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 1 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026066 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 2,3-dihydroxy-2-methylbutyrate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026067 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 2,3-dihydroxyisovalerate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026068 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 2-aminobutyrate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026069 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 2-aminophenol sulfate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026070 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 2-hydroxy-3-methylvalerate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026071 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 2-hydroxyadipate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 1 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026072 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 2-hydroxybutyrate/2-hydroxyisobutyrate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026073 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 2-hydroxyglutarate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026074 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 2-oxoadipate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026075 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 2-piperidinone levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026076 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 5-methylcytidine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026103 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 6-oxopiperidine-2-carboxylate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026106 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 7-methylguanine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026108 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 7-methylxanthine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026109 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Alanine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026114 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Alpha-ketoglutaramate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026117 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Alpha-tocopherol levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026118 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Arabinose levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026119 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Ascorbate (vitamin c) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026126 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 5-hydroxyindoleacetate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026102 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Acetylcarnitine (c2) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026110 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Arabitol/xylitol levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026120 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Arabonate/xylonate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026121 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Arachidonate (20:4n6) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026122 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Argininate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026123 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Arginine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026124 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 5-methylthioadenosine (mta) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026104 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 5-methyluridine (ribothymidine) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026105 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 7-alpha-hydroxy-3-oxo-4-cholestenoate (7-hoca) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026107 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Acisoga levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026111 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Adenine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026112 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Adenosine 3',5'-cyclic monophosphate (camp) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026113 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Alpha-hydroxyisocaproate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026115 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Alpha-hydroxyisovalerate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026116 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Argininosuccinate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026125 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-(4-hydroxyphenyl)lactate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026077 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-carboxy-4-methyl-5-propyl-2-furanpropanoate (cmpf) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026078 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-hydroxy-2-ethylpropionate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026079 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-hydroxy-3-methylglutarate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026080 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-hydroxybutyrate (bhba) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026081 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-hydroxyhexanoate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026082 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-hydroxyoctanoate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026083 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-hydroxypyridine sulfate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026084 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-hydroxystachydrine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026085 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-methoxytyramine sulfate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026086 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-methoxytyrosine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026087 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-methyl-2-oxobutyrate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026088 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-methyl-2-oxovalerate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026089 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-methylglutaconate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026090 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-methylglutarylcarnitine (2) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026091 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-methylhistidine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026092 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-methylxanthine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026093 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 3-ureidopropionate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 1 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026094 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 4-acetamidobutanoate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026095 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 4-methyl-2-oxopentanoate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026096 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 4-methylcatechol sulfate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026097 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 5,6-dihydrothymine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026098 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 5,6-dihydrouridine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026099 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 5-acetylamino-6-amino-3-methyluracil levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026100 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. 5-hydroxyhexanoate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026101 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Behenoyl sphingomyelin (d18:1/22:0) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026127 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Benzoate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026128 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Beta-alanine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026129 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Beta-citrylglutamate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026130 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Beta-hydroxyisovalerate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026131 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Betaine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 1 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026132 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. C-glycosyltryptophan levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026133 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Caffeine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026134 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Carboxyethyl-gaba levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026135 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Carnitine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026136 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Catechol sulfate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026137 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Choline levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026138 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Choline phosphate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026139 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Citramalate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026140 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Citrate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026141 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Cortisone levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026142 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Creatine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026143 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Cys-gly, oxidized levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026144 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Cysteine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026145 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Cysteinylglycine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026146 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Cysteinylglycine disulfide levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026147 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Cytidine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026148 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Deoxycarnitine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026149 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Diglycerol levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026150 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Dimethyl sulfone levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026151 Genome-wide genotyping array 291 2021-09-28 33985508 Williams CJ 2021-05-13 J Biomed Sci www.ncbi.nlm.nih.gov/pubmed/33985508 Genome wide association study of response to interval and continuous exercise training: the Predict-HIIT study. Peak oxygen uptake response following exercise training 507 European ancestry individuals 39 European ancestry individuals Illumina [NR] (imputed) 0 maximal oxygen uptake measurement, response to exercise http://www.ebi.ac.uk/efo/EFO_0004887, http://www.ebi.ac.uk/efo/EFO_0007768 GCST012405 Genome-wide genotyping array 507 2021-07-27 33385171 Hagg S 2020-12-31 Hum Genet www.ncbi.nlm.nih.gov/pubmed/33385171 Deciphering the genetic and epidemiological landscape of mitochondrial DNA abundance. Mitochondrial DNA levels 295,150 European ancestry individuals NA Affymetrix [3505788] (imputed) 66 mitochondrial DNA measurement http://www.ebi.ac.uk/efo/EFO_0006312 GCST012072 Genome-wide genotyping array 295150 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Dimethylarginine (sdma + adma) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026152 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Dimethylmalonic acid levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026153 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Dopamine 3-o-sulfate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026154 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Ergothioneine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026155 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Erythritol levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026156 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Erythronate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026157 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Ethylmalonate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 1 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026158 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Fructose levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026159 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Galactonate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026160 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Galactosylglycerol levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026161 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Gamma-glutamyl-alpha-lysine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026162 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Gamma-glutamylglutamine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026163 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Gamma-glutamylleucine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026164 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Gamma-glutamylphenylalanine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026165 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Gamma-glutamylthreonine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026166 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Gamma-glutamylvaline levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026167 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Gluconate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026168 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Glutamate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026169 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Glutamine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026170 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Glutarylcarnitine (c5-dc) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026171 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Glycerate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026172 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Glycerol levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026173 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Glycerophosphoinositol levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026174 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Guaiacol sulfate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026175 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Guanosine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 1 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026176 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Gulonate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026177 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Hippurate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026178 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Histidine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026179 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Homoarginine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026180 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Homocarnosine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026181 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Homostachydrine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026182 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Homovanillate (hva) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026183 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Hydroxy-cmpf levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026184 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Hydroxyasparagine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026185 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Indoleacetate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026186 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Isobutyrylcarnitine (c4) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026187 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Isocitrate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026188 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Isoleucine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026189 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Isovalerate (i5:0) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026190 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Kynurenate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026191 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Leucine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026192 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Maleate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026193 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Mannitol/sorbitol levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026194 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Mannose levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026195 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Methionine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026196 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Methionine sulfone levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 1 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026197 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Methionine sulfoxide levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026198 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Methyl glucopyranoside (alpha + beta) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026199 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Methylmalonate (mma) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026200 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Methylsuccinate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026201 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Methylsuccinoylcarnitine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026202 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Myo-inositol levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026203 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetyl-3-methylhistidine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026204 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetyl-aspartyl-glutamate (naag) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026205 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetyl-beta-alanine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 1 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026206 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetyl-isoputreanine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026207 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetylalanine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026208 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetylarginine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026209 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetylasparagine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026210 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetylaspartate (naa) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026211 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetylglucosamine/n-acetylgalactosamine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026212 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetylglutamate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 1 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026213 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetylglutamine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026214 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetylglycine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026215 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetylhistidine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 1 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026216 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetylisoleucine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026217 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetylleucine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026218 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetylmethionine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026219 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetylneuraminate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026220 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetylphenylalanine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026221 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetylputrescine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026222 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetylserine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026223 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetyltaurine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026224 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetylthreonine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026225 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-acetylvaline levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026226 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-delta-acetylornithine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 1 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026227 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-formylanthranilic acid levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026228 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-formylmethionine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026229 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N-trimethyl 5-aminovalerate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026230 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N1-methyl-2-pyridone-5-carboxamide levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026231 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N1-methyladenosine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026232 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N1-methylinosine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026233 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N2,n2-dimethylguanosine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026234 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N6,n6,n6-trimethyllysine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026235 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N6-carbamoylthreonyladenosine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026236 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. N6-succinyladenosine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026237 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Nicotinamide riboside levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026238 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. O-sulfo-l-tyrosine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026239 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Octanoylcarnitine (c8) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026240 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Orotate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026241 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Orotidine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026242 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Oxalate (ethanedioate) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 1 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026243 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Palmitoyl dihydrosphingomyelin (d18:0/16:0) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026244 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Palmitoyl sphingomyelin (d18:1/16:0) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026245 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Pantothenate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026246 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Phenol sulfate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026247 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Phenylacetylglutamine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026248 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Phenylalanine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026249 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Phenyllactate (pla) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026250 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Pipecolate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026251 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Propionylcarnitine (c3) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026252 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Pseudouridine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026253 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Pyridoxal levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026254 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Pyridoxate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026255 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Pyruvate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026256 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Quinate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026257 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Ribitol levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026258 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Ribonate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026259 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Ribulonate/xylulonate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026260 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. S-1-pyrroline-5-carboxylate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026261 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. S-methylcysteine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026262 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Salicylate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026263 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Serine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026264 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Spermidine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026265 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Stachydrine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026266 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Stearoyl sphingomyelin (d18:1/18:0) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026267 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Succinimide levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026268 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Succinylcarnitine (c4-dc) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026269 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Tartarate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026270 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Tartronate (hydroxymalonate) levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026271 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Theobromine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026272 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Theophylline levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026273 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Thioproline levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026274 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Threonate levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026275 Genome-wide genotyping array 291 2021-08-24 33437055 Panyard DJ 2021-01-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33437055 Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. Threonine levels 291 European ancestry individuals NA Illumina [7049691] (imputed) 0 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST90026276 Genome-wide genotyping array 291 2021-06-29 33093602 Chen IC 2020-10-22 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33093602 CUX2, BRAP and ALDH2 are associated with metabolic traits in people with excessive alcohol consumption. Excessive alcohol consumption 1,945 Taiwanese cases, 16,418 Taiwanese controls NA Affymetrix [6410722] (imputed) 3 alcohol consumption measurement http://www.ebi.ac.uk/efo/EFO_0007878 GCST011979 Genome-wide genotyping array 18363 2021-06-29 33093602 Chen IC 2020-10-22 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33093602 CUX2, BRAP and ALDH2 are associated with metabolic traits in people with excessive alcohol consumption. Gamma glutamyl transferase levels 18,363 Taiwanese individuals NA Affymetrix [6410722] (imputed) 1 serum gamma-glutamyl transferase measurement http://www.ebi.ac.uk/efo/EFO_0004532 GCST011978 Genome-wide genotyping array 18363 2021-05-19 33087363 Xu W 2020-10-21 Sci Adv www.ncbi.nlm.nih.gov/pubmed/33087363 The FAM171A2 gene is a key regulator of progranulin expression and modifies the risk of multiple neurodegenerative diseases. Cerebrospinal fluid progranulin levels 432 European ancestry individuals 930 Han Chinese ancestry individuals Illumina [3262988] (imputed) 10 progranulin measurement http://www.ebi.ac.uk/efo/EFO_0004625 GCST011705 Genome-wide genotyping array 432 2020-10-16 32527199 van Duijvenboden S 2020-06-11 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/32527199 Genetic Basis and Prognostic Value of Exercise QT Dynamics. QT dynamics during exercise 28,449 European ancestry women, 24,412 European ancestry men NA Affymetrix [9800000] (imputed) 44 QT interval http://www.ebi.ac.uk/efo/EFO_0004682 GCST90010359 Genome-wide genotyping array 52861 2020-10-16 32527199 van Duijvenboden S 2020-06-11 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/32527199 Genetic Basis and Prognostic Value of Exercise QT Dynamics. QT dynamics during recovery from exercise 51,503 European ancestry individuals NA Affymetrix [9800000] (imputed) 3 QT interval http://www.ebi.ac.uk/efo/EFO_0004682 GCST90010360 Genome-wide genotyping array 51503 2021-06-04 32970095 Clifford RE 2020-09-24 JAMA Otolaryngol Head Neck Surg www.ncbi.nlm.nih.gov/pubmed/32970095 Novel Risk Loci in Tinnitus and Causal Inference With Neuropsychiatric Disorders Among Adults of European Ancestry. Tinnitus 172,995 European ancestry individuals 94,755 European ancestry cases, 166,077 European ancestry controls Affymetrix [up to 96000000] (imputed) 1 Tinnitus http://purl.obolibrary.org/obo/HP_0000360 GCST011785 Genome-wide genotyping array 172995 2021-07-01 33201861 Lahm H 2020-11-17 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/33201861 Congenital heart disease risk loci identified by genome-wide association study in European patients. Congenital heart disease 4,034 European ancestry cases, 8,486 European ancestry controls NA Affymetrix, Illumina [9216527] (imputed) 1 congenital heart disease http://www.ebi.ac.uk/efo/EFO_0005207 GCST011989 Genome-wide genotyping array 12520 2021-07-01 33201861 Lahm H 2020-11-17 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/33201861 Congenital heart disease risk loci identified by genome-wide association study in European patients. Congenital heart disease (transposition of the great arteries) 399 European ancestry cases, 8,486 European ancestry controls NA Affymetrix, Illumina [9216527] (imputed) 2 transposition of the great arteries http://purl.obolibrary.org/obo/MONDO_0000153 GCST011988 Genome-wide genotyping array 8885 2021-07-01 33201861 Lahm H 2020-11-17 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/33201861 Congenital heart disease risk loci identified by genome-wide association study in European patients. Congenital right-sided heart lesions 1,296 European ancestry cases, 8,486 European ancestry controls NA Affymetrix, Illumina [9216527] (imputed) 1 congenital right-sided heart lesions http://www.ebi.ac.uk/efo/EFO_0600032 GCST011987 Genome-wide genotyping array 9782 2021-07-01 33201861 Lahm H 2020-11-17 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/33201861 Congenital heart disease risk loci identified by genome-wide association study in European patients. Congenital left-sided heart lesions 326 European ancestry cases, 8,486 European ancestry controls NA Affymetrix, Illumina [9216527] (imputed) 3 congenital left-sided heart lesions http://www.ebi.ac.uk/efo/EFO_0005938 GCST011986 Genome-wide genotyping array 8812 2021-07-01 33201861 Lahm H 2020-11-17 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/33201861 Congenital heart disease risk loci identified by genome-wide association study in European patients. Congenital heart disease (septal defects) 1,074 European ancestry cases, 8,486 European ancestry controls NA Affymetrix, Illumina [9216527] (imputed) 5 heart septal defect http://purl.obolibrary.org/obo/MONDO_0002078 GCST011985 Genome-wide genotyping array 9560 2021-07-01 33201861 Lahm H 2020-11-17 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/33201861 Congenital heart disease risk loci identified by genome-wide association study in European patients. Congenital heart disease (anomalies of thoracic arteries and veins) 486 European ancestry cases, 8,486 European ancestry controls NA Affymetrix, Illumina [9216527] (imputed) 2 Abnormality of cardiovascular system morphology http://purl.obolibrary.org/obo/HP_0030680 GCST011984 Genome-wide genotyping array 8972 2021-05-06 33888908 Pirastu N 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888908 Genetic analyses identify widespread sex-differential participation bias. Biological sex 1,301,549 European ancestry cases, 1,160,583 European ancestry controls NA Illumina [13288253] (imputed) 158 biological sex http://purl.obolibrary.org/obo/PATO_0000047 GCST90013473 Genome-wide genotyping array 2462132 2021-05-06 33888908 Pirastu N 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888908 Genetic analyses identify widespread sex-differential participation bias. Biological sex (age adjusted) 245,351 European ancestry cases, 206,951 European ancestry controls NA Affymetrix [25647815] (imputed) 0 biological sex http://purl.obolibrary.org/obo/PATO_0000047 GCST90013474 Genome-wide genotyping array 452302 2020-12-15 25387710 Vrieze SI 2014-12-01 Psychophysiology www.ncbi.nlm.nih.gov/pubmed/25387710 In search of rare variants: preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes. P3 amplitude reduction 4,166 European ancestry individuals NA NR [21426324] (imputed) 0 electroencephalogram measurement http://www.ebi.ac.uk/efo/EFO_0004357 GCST90012808 Genome-wide genotyping array, Genome-wide sequencing 4166 2020-12-15 25387710 Vrieze SI 2014-12-01 Psychophysiology www.ncbi.nlm.nih.gov/pubmed/25387710 In search of rare variants: preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes. P3 genetic factor 3,088 European ancestry individuals NA NR [19284812] (imputed) 0 electroencephalogram measurement http://www.ebi.ac.uk/efo/EFO_0004357 GCST90012809 Genome-wide genotyping array, Genome-wide sequencing 3088 2020-12-15 25387710 Vrieze SI 2014-12-01 Psychophysiology www.ncbi.nlm.nih.gov/pubmed/25387710 In search of rare variants: preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes. Antisaccade tracking error rate 4,469 European ancestry individuals NA NR [21812431] (imputed) 1 antisaccade response measurement http://www.ebi.ac.uk/efo/EFO_0006874 GCST90012810 Genome-wide genotyping array, Genome-wide sequencing 4469 2020-12-15 25387710 Vrieze SI 2014-12-01 Psychophysiology www.ncbi.nlm.nih.gov/pubmed/25387710 In search of rare variants: preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes. Skin conductance level 3,791 European ancestry individuals NA NR [21085834] (imputed) 0 electrodermal activity measurement http://www.ebi.ac.uk/efo/EFO_0006866 GCST90012811 Genome-wide genotyping array, Genome-wide sequencing 3791 2020-12-15 25387710 Vrieze SI 2014-12-01 Psychophysiology www.ncbi.nlm.nih.gov/pubmed/25387710 In search of rare variants: preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes. Electrodermal activity factor 4,424 European ancestry individuals NA NR [21774103] (imputed) 0 electrodermal activity measurement http://www.ebi.ac.uk/efo/EFO_0006866 GCST90012812 Genome-wide genotyping array, Genome-wide sequencing 4424 2020-12-15 25387710 Vrieze SI 2014-12-01 Psychophysiology www.ncbi.nlm.nih.gov/pubmed/25387710 In search of rare variants: preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes. Overall startle response 3,323 European ancestry individuals NA NR [19722535] (imputed) 1 acoustic startle blink response measurement http://www.ebi.ac.uk/efo/EFO_0006875 GCST90012813 Genome-wide genotyping array, Genome-wide sequencing 3323 2020-12-15 25387710 Vrieze SI 2014-12-01 Psychophysiology www.ncbi.nlm.nih.gov/pubmed/25387710 In search of rare variants: preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes. Aversive difference startle modulation 3,321 European ancestry individuals NA NR [19719458] (imputed) 2 acoustic startle blink response measurement http://www.ebi.ac.uk/efo/EFO_0006875 GCST90012814 Genome-wide genotyping array, Genome-wide sequencing 3321 2020-12-15 25387710 Vrieze SI 2014-12-01 Psychophysiology www.ncbi.nlm.nih.gov/pubmed/25387710 In search of rare variants: preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes. Pleasant difference startle modulation 3,322 European ancestry individuals NA NR [19720993] (imputed) 1 acoustic startle blink response measurement http://www.ebi.ac.uk/efo/EFO_0006875 GCST90012815 Genome-wide genotyping array, Genome-wide sequencing 3322 2020-12-15 25387710 Vrieze SI 2014-12-01 Psychophysiology www.ncbi.nlm.nih.gov/pubmed/25387710 In search of rare variants: preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes. Skin conductance response frequency 4,299 European ancestry individuals NA NR [21572833] (imputed) 0 electrodermal activity measurement http://www.ebi.ac.uk/efo/EFO_0006866 GCST90012816 Genome-wide genotyping array, Genome-wide sequencing 4299 2020-12-15 25387710 Vrieze SI 2014-12-01 Psychophysiology www.ncbi.nlm.nih.gov/pubmed/25387710 In search of rare variants: preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes. Skin conductance response amplitude 4,102 European ancestry individuals NA NR [21289320] (imputed) 1 electrodermal activity measurement http://www.ebi.ac.uk/efo/EFO_0006866 GCST90012817 Genome-wide genotyping array, Genome-wide sequencing 4102 2020-12-15 25387710 Vrieze SI 2014-12-01 Psychophysiology www.ncbi.nlm.nih.gov/pubmed/25387710 In search of rare variants: preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes. Alpha electroencephalogram power 3,948 European ancestry individuals NA NR [20980108] (imputed) 0 electroencephalogram measurement http://www.ebi.ac.uk/efo/EFO_0004357 GCST90012818 Genome-wide genotyping array, Genome-wide sequencing 3948 2020-12-15 25387710 Vrieze SI 2014-12-01 Psychophysiology www.ncbi.nlm.nih.gov/pubmed/25387710 In search of rare variants: preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes. Beta electroencephalogram power 3,948 European ancestry individuals NA NR [20980108] (imputed) 3 electroencephalogram measurement http://www.ebi.ac.uk/efo/EFO_0004357 GCST90012819 Genome-wide genotyping array, Genome-wide sequencing 3948 2020-12-15 25387710 Vrieze SI 2014-12-01 Psychophysiology www.ncbi.nlm.nih.gov/pubmed/25387710 In search of rare variants: preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes. Theta electroencephalogram power 3,948 European ancestry individuals NA NR [20980108] (imputed) 1 electroencephalogram measurement http://www.ebi.ac.uk/efo/EFO_0004357 GCST90012820 Genome-wide genotyping array, Genome-wide sequencing 3948 2020-12-15 25387710 Vrieze SI 2014-12-01 Psychophysiology www.ncbi.nlm.nih.gov/pubmed/25387710 In search of rare variants: preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes. Delta electroencephalogram power 3,948 European ancestry individuals NA NR [20980108] (imputed) 0 electroencephalogram measurement http://www.ebi.ac.uk/efo/EFO_0004357 GCST90012821 Genome-wide genotyping array, Genome-wide sequencing 3948 2020-12-15 25387710 Vrieze SI 2014-12-01 Psychophysiology www.ncbi.nlm.nih.gov/pubmed/25387710 In search of rare variants: preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes. Total electroencephalogram power 3,948 European ancestry individuals NA NR [20980108] (imputed) 0 electroencephalogram measurement http://www.ebi.ac.uk/efo/EFO_0004357 GCST90012822 Genome-wide genotyping array, Genome-wide sequencing 3948 2020-12-15 25387710 Vrieze SI 2014-12-01 Psychophysiology www.ncbi.nlm.nih.gov/pubmed/25387710 In search of rare variants: preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes. Alpha electroencephalogram power O1O2 3,966 European ancestry individuals NA NR [21032956] (imputed) 0 electroencephalogram measurement http://www.ebi.ac.uk/efo/EFO_0004357 GCST90012823 Genome-wide genotyping array, Genome-wide sequencing 3966 2020-12-15 25387710 Vrieze SI 2014-12-01 Psychophysiology www.ncbi.nlm.nih.gov/pubmed/25387710 In search of rare variants: preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes. Alpha electroencephalogram frequency O1O2 3,966 European ancestry individuals NA NR [21032956] (imputed) 2 electroencephalogram measurement http://www.ebi.ac.uk/efo/EFO_0004357 GCST90012824 Genome-wide genotyping array, Genome-wide sequencing 3966 2021-01-22 33311586 Yonova-Doing E 2020-12-11 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33311586 Common variants in SOX-2 and congenital cataract genes contribute to age-related nuclear cataract. Age-related nuclear cataracts 7,352 European ancestry individuals, 2,230 Chinese ancestry individuals, 2,369 Malay ancestry individuals, 2,200 Indian ancestry individuals 941 European ancestry cases, 922 European ancestry controls, 769 Chinese ancestry cases, 759 Chinese ancestry controls, 1,097 indian ancestry cases, 811 indian ancestry controls Illumina [8500000] (imputed) 8 Age-related nuclear cataract http://purl.obolibrary.org/obo/HP_0011142 GCST90013423 Genome-wide genotyping array 14151 2020-10-01 32949544 Jones E 2020-09-16 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/32949544 Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study. Creutzfeldt-Jakob disease (sporadic) 4,110 European ancestry cases, 13,569 European ancestry controls 1,098 European ancestry cases, 498 ,016 European ancestry controls Affymetrix, Illumina [6314492] (imputed) 4 sporadic Creutzfeld Jacob disease http://www.ebi.ac.uk/efo/EFO_1000656 GCST90001389 Genome-wide genotyping array 17679 2021-04-21 32920024 Sanna M 2020-09-10 J Invest Dermatol www.ncbi.nlm.nih.gov/pubmed/32920024 Looking for Sunshine: Genetic Predisposition to Sun-Seeking in 265,000 Individuals of European Ancestry. Sun-seeking behavior 261,915 European ancestry individuals NA Affymetrix, Illumina [8385325] (imputed) 5 sun exposure measurement http://www.ebi.ac.uk/efo/EFO_0010729 GCST011534 Genome-wide genotyping array 261915 2021-07-01 33713608 Graff M 2021-03-05 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/33713608 Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry. Height 41,389 African ancestry individuals 11,364 African ancestry individuals, 253,288 European ancestry individuals Affymetrix, Illumina [17972582] (imputed) 74 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST90013466 Genome-wide genotyping array 41389 2021-07-01 33713608 Graff M 2021-03-05 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/33713608 Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry. Height 16,021 African ancestry men 2,915 African ancestry men, up to 253,288 European ancestry men Affymetrix, Illumina [16055004] (imputed) 18 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST90013467 Genome-wide genotyping array 16021 2021-07-01 33713608 Graff M 2021-03-05 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/33713608 Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry. Height 25,369 African ancestry women 8,449 African ancestry women, up to 253,288 European ancestry women Affymetrix, Illumina [19885954] (imputed) 30 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST90013468 Genome-wide genotyping array 25369 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Schizophrenia vs autism spectrum disorder (ordinary least squares (OLS)) 40,675 schizophrenia cases, 18,381 autism spectrum disorder cases NA NR [4484088] (imputed) 40 schizophrenia, autism spectrum disorder http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0003756 GCST90016620 Genome-wide genotyping array 59056 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Schizophrenia vs bipolar disorder (ordinary least squares (OLS)) 40,675 schizophrenia cases, 20,352 bipolar disorder cases NA NR [4548414] (imputed) 12 schizophrenia, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0000289 GCST90016621 Genome-wide genotyping array 61027 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Schizophrenia vs major depressive disorder (ordinary least squares (OLS)) 33,640 schizophrenia cases, 59,851 MDD cases 7,035 schizophrenia cases, 111,175 MDD cases NR [4483387] (imputed) 1 unipolar depression, schizophrenia http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000692 GCST90016622 Genome-wide genotyping array 93491 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Schizophrenia vs obsessive compulsive disorder (ordinary least squares (OLS)) 40,675 schizophrenia cases, 2,688 OCD cases NA NR [4503720] (imputed) 0 obsessive-compulsive disorder, schizophrenia http://www.ebi.ac.uk/efo/EFO_0004242, http://www.ebi.ac.uk/efo/EFO_0000692 GCST90016623 Genome-wide genotyping array 43363 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Schizophrenia vs Tourette's syndrome and other tic disorders (ordinary least squares (OLS)) 40,675 schizophrenia cases, 4,819 Tourette's syndrome cases NA NR [4502103] (imputed) 13 Tourette syndrome, schizophrenia http://www.ebi.ac.uk/efo/EFO_0004895, http://www.ebi.ac.uk/efo/EFO_0000692 GCST90016624 Genome-wide genotyping array 45494 2021-04-27 33686288 Peyrot WJ 2021-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33686288 Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. Ulcerative colitis vs rheumatoid arthritis (ordinary least squares (OLS)) 6,968 ulcerative colitis cases, 8,875 rheumatoid arthritis cases 10,679 ulcerative colitis cases, 5,486 rheumatoid arthritis cases NR [5896510] (imputed) 15 rheumatoid arthritis, ulcerative colitis http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0000729 GCST90016625 Genome-wide genotyping array 15843 2021-07-07 33382404 Sallinen RJ 2020-12-31 J Nutr www.ncbi.nlm.nih.gov/pubmed/33382404 Genetic Risk Score for Serum 25-Hydroxyvitamin D Concentration Helps to Guide Personalized Vitamin D Supplementation in Healthy Finnish Adults. Serum 25-Hydroxyvitamin D levels 3,399 Finnish ancestry individuals NA Illumina [~ 7700000] (imputed) 2 vitamin D measurement http://www.ebi.ac.uk/efo/EFO_0004631 GCST012014 Genome-wide genotyping array 3399 2021-07-27 33495597 Harper AR 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495597 Common genetic variants and modifiable risk factors underpin hypertrophic cardiomyopathy susceptibility and expressivity. Hypertrophic cardiomyopathy 233 African ancestry cases, 122 Hispanic/Latino cases, 70 East Asian ancestry cases, 2,196 European ancestry cases, 138 South Asian ancestry cases, 21 cases, 1,331 African ancestry controls, 170 Hispanic/Latino controls, 333 East Asian ancestry controls, 42,902 European ancestry controls, 1,727 South Asian ancestry controls, 1,023 controls 1,643 European or unknown ancestry cases, 6,628 European or unknown ancestry controls Affymetrix [8590397] (imputed) 12 hypertrophic cardiomyopathy http://www.ebi.ac.uk/efo/EFO_0000538 GCST012101 Genome-wide genotyping array, Genome-wide sequencing 50266 2021-07-27 33495597 Harper AR 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495597 Common genetic variants and modifiable risk factors underpin hypertrophic cardiomyopathy susceptibility and expressivity. Hypertrophic cardiomyopathy (sarcomere positive) 54 African ancestry cases, 28 Hispanic/Latino cases, 18 East Asian ancestry cases, 728 European ancestry cases, 43 South Asian ancestry cases, 593 African ancestry controls, 92 Hispanic/Latino controls, 121 East Asian ancestry controls, 18,791 European ancestry controls, 595 South Asian ancestry controls NA Affymetrix [8590397] (imputed) 20 hypertrophic cardiomyopathy http://www.ebi.ac.uk/efo/EFO_0000538 GCST012100 Genome-wide genotyping array 21063 2021-07-27 33495597 Harper AR 2021-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33495597 Common genetic variants and modifiable risk factors underpin hypertrophic cardiomyopathy susceptibility and expressivity. Hypertrophic cardiomyopathy (sarcomere negative) 170 African ancestry cases, 93 Hispanic/Latino cases, 52 East Asian ancestry cases, 1,444 European ancestry cases, 94 South Asian ancestry cases, 21 cases, 738 African ancestry controls, 78 Hispanic/Latino controls, 212 East Asian ancestry controls, 24,161 European ancestry controls, 1,132 South Asian ancestry controls, 1,023 controls NA Affymetrix [8590397] (imputed) 25 hypertrophic cardiomyopathy http://www.ebi.ac.uk/efo/EFO_0000538 GCST012099 Genome-wide genotyping array, Genome-wide sequencing 29218 2021-11-01 34488071 Crist RC 2021-08-28 Drug Alcohol Depend www.ncbi.nlm.nih.gov/pubmed/34488071 Analysis of genetic and clinical factors associated with buprenorphine response. Response to buprenorphine in opioid use disorder 1,609 European ancestry individuals NA Affymetrix [NR] (imputed) 6 response to opioid http://www.ebi.ac.uk/efo/EFO_0008541 GCST90044777 Genome-wide genotyping array 1609 2021-10-22 34212547 An J 2021-07-01 Allergy Asthma Immunol Res www.ncbi.nlm.nih.gov/pubmed/34212547 Genome-Wide Association Study of Korean Asthmatics: A Comparison With UK Asthmatics. Adult asthma 1,386 Korean ancestry cases, 5,205 Korean ancestry controls NA Affymetrix [4922160] (imputed) 10 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST90025849 Genome-wide genotyping array 6591 2021-11-02 34224794 Wang K 2021-07-02 Prog Neuropsychopharmacol Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34224794 Genome-wide association study identified INSC gene associated with Trail Making Test Part A and Alzheimer's disease related cognitive phenotypes. Perceptual and visual search speed (trail making test A) 684 European ancestry individuals, 17 Hispanic individuals, 36 African American individuals, 18 individuals NA NR [534934] 5 information processing speed http://www.ebi.ac.uk/efo/EFO_0004363 GCST90025850 Genome-wide genotyping array 755 2021-11-02 34224794 Wang K 2021-07-02 Prog Neuropsychopharmacol Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34224794 Genome-wide association study identified INSC gene associated with Trail Making Test Part A and Alzheimer's disease related cognitive phenotypes. Executive function (trail making test B) 684 European ancestry individuals, 17 Hispanic individuals, 36 African American individuals, 18 individuals NA NR [534934] 3 executive function measurement http://www.ebi.ac.uk/efo/EFO_0009332 GCST90025851 Genome-wide genotyping array 755 2021-11-02 34224794 Wang K 2021-07-02 Prog Neuropsychopharmacol Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34224794 Genome-wide association study identified INSC gene associated with Trail Making Test Part A and Alzheimer's disease related cognitive phenotypes. Disability level (impaired activities of daily living) 684 European ancestry individuals, 17 Hispanic individuals, 36 African American individuals, 18 individuals NA NR [534934] 12 activities of daily living score measurement http://www.ebi.ac.uk/efo/EFO_0008451 GCST90025852 Genome-wide genotyping array 755 2021-11-02 34224794 Wang K 2021-07-02 Prog Neuropsychopharmacol Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34224794 Genome-wide association study identified INSC gene associated with Trail Making Test Part A and Alzheimer's disease related cognitive phenotypes. Global cognition (Clinical Dementia Rating Scale Sum of Boxes) 684 European ancestry individuals, 17 Hispanic individuals, 36 African American individuals, 18 individuals NA NR [534934] 8 cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0008354 GCST90025853 Genome-wide genotyping array 755 2021-11-02 34224794 Wang K 2021-07-02 Prog Neuropsychopharmacol Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/34224794 Genome-wide association study identified INSC gene associated with Trail Making Test Part A and Alzheimer's disease related cognitive phenotypes. Cognitive impairment level 684 European ancestry individuals, 17 Hispanic individuals, 36 African American individuals, 18 individuals NA NR [534934] 7 cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0008354 GCST90025854 Genome-wide genotyping array 755 2021-09-30 34032881 Du M 2021-05-25 Intensive Care Med www.ncbi.nlm.nih.gov/pubmed/34032881 Integrative omics provide biological and clinical insights into acute respiratory distress syndrome. Acute respiratory distress syndrome 1,250 European ancestry cases, 1,583 European ancestry controls, 387 African American cases, 387 African American controls NA Illumina [3817416] (imputed) 3 acute respiratory distress syndrome http://www.ebi.ac.uk/efo/EFO_1000637 GCST012418 Genome-wide genotyping array 3607 2021-10-15 34343768 Chu X 2021-07-01 Sleep Med www.ncbi.nlm.nih.gov/pubmed/34343768 Insomnia affects the levels of plasma bilirubin and protein metabolism: an observational study and GWGEIS in UK Biobank cohort. Direct bilirubin levels x insomnia interaction 85,121 cases with insomnia, 74,733 controls without insomnia NA Affymetrix [NR] (imputed) 82 insomnia, bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004698, http://www.ebi.ac.uk/efo/EFO_0004570 GCST90026656 Genome-wide genotyping array 159854 2021-10-15 34343768 Chu X 2021-07-01 Sleep Med www.ncbi.nlm.nih.gov/pubmed/34343768 Insomnia affects the levels of plasma bilirubin and protein metabolism: an observational study and GWGEIS in UK Biobank cohort. Total bilirubin levels x insomnia interaction 101,922 cases with insomnia, 84,871 controls with insomnia NA Affymetrix [NR] (imputed) 85 insomnia, bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004698, http://www.ebi.ac.uk/efo/EFO_0004570 GCST90026657 Genome-wide genotyping array 186793 2021-10-15 34343768 Chu X 2021-07-01 Sleep Med www.ncbi.nlm.nih.gov/pubmed/34343768 Insomnia affects the levels of plasma bilirubin and protein metabolism: an observational study and GWGEIS in UK Biobank cohort. Total protein levels x insomnia interaction 93,452 cases with insomnia, 78,122 controls without insomnia NA Affymetrix [NR] (imputed) 266 insomnia, total blood protein measurement http://www.ebi.ac.uk/efo/EFO_0004698, http://www.ebi.ac.uk/efo/EFO_0004536 GCST90026658 Genome-wide genotyping array 171574 2021-10-19 34075027 Gonda X 2021-06-01 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/34075027 Genetic underpinnings of affective temperaments: a pilot GWAS investigation identifies a new genome-wide significant SNP for anxious temperament in ADGRB3 gene. Anxious temperament 775 European ancestry individuals NA Illumina [2550710] (imputed) 6 TEMPS-A questionnaire http://www.ebi.ac.uk/efo/EFO_0004783 GCST90020036 Genome-wide genotyping array 775 2021-10-19 34075027 Gonda X 2021-06-01 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/34075027 Genetic underpinnings of affective temperaments: a pilot GWAS investigation identifies a new genome-wide significant SNP for anxious temperament in ADGRB3 gene. Cyclothymic temperament 775 European ancestry individuals NA Illumina [2550710] (imputed) 5 TEMPS-A questionnaire http://www.ebi.ac.uk/efo/EFO_0004783 GCST90020037 Genome-wide genotyping array 775 2021-10-19 34075027 Gonda X 2021-06-01 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/34075027 Genetic underpinnings of affective temperaments: a pilot GWAS investigation identifies a new genome-wide significant SNP for anxious temperament in ADGRB3 gene. Depressive temperament 775 European ancestry individuals NA Illumina [2550710] (imputed) 3 TEMPS-A questionnaire http://www.ebi.ac.uk/efo/EFO_0004783 GCST90020038 Genome-wide genotyping array 775 2021-10-19 34075027 Gonda X 2021-06-01 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/34075027 Genetic underpinnings of affective temperaments: a pilot GWAS investigation identifies a new genome-wide significant SNP for anxious temperament in ADGRB3 gene. Irritable temperament 775 European ancestry individuals NA Illumina [2550710] (imputed) 2 TEMPS-A questionnaire http://www.ebi.ac.uk/efo/EFO_0004783 GCST90020039 Genome-wide genotyping array 775 2021-10-19 34075027 Gonda X 2021-06-01 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/34075027 Genetic underpinnings of affective temperaments: a pilot GWAS investigation identifies a new genome-wide significant SNP for anxious temperament in ADGRB3 gene. Hyperthymic temperament 775 European ancestry individuals NA Illumina [2550710] (imputed) 4 TEMPS-A questionnaire http://www.ebi.ac.uk/efo/EFO_0004783 GCST90020040 Genome-wide genotyping array 775 2021-10-05 33979311 Yanik EL 2021-05-12 J Bone Joint Surg Am www.ncbi.nlm.nih.gov/pubmed/33979311 Identification of a Novel Genetic Marker for Risk of Degenerative Rotator Cuff Disease Surgery in the UK Biobank. Degenerative rotator cuff disease surgery 2,917 British ancestry cases, 14,158 British ancestry controls NA Affymetrix [10815322] (imputed) 1 rotator cuff tear http://www.ebi.ac.uk/efo/EFO_1001250 GCST90020231 Genome-wide genotyping array 17075 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Basophil count 11,502 African American or Afro-Caribbean and African ancestry individuals NA Affymetrix, Illumina [35912980] (imputed) 0 basophil count http://www.ebi.ac.uk/efo/EFO_0005090 GCST90002291 Genome-wide genotyping array 11502 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Basophil count 474,001 European ancestry individuals NA Affymetrix, Illumina [50036608] (imputed) 170 basophil count http://www.ebi.ac.uk/efo/EFO_0005090 GCST90002292 Genome-wide genotyping array 474001 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Basophil count 81,042 East Asian ancestry individuals NA Affymetrix, Illumina [16286709] (imputed) 25 basophil count http://www.ebi.ac.uk/efo/EFO_0005090 GCST90002293 Genome-wide genotyping array 81042 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Basophil count 2,969 Hispanic or Latin American individuals NA Affymetrix, Illumina [23758884] (imputed) 1 basophil count http://www.ebi.ac.uk/efo/EFO_0005090 GCST90002294 Genome-wide genotyping array 2969 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Basophil count 8,149 South Asian ancestry individuals NA Affymetrix, Illumina [28457669] (imputed) 0 basophil count http://www.ebi.ac.uk/efo/EFO_0005090 GCST90002295 Genome-wide genotyping array 8149 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Basophil count 577,663 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals NA Affymetrix, Illumina [19905671] (imputed) 150 basophil count http://www.ebi.ac.uk/efo/EFO_0005090 GCST90002296 Genome-wide genotyping array 577663 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Eosinophil counts 11,615 African American or Afro-Caribbean and African ancestry individuals NA Affymetrix, Illumina [35935203] (imputed) 1 eosinophil count http://www.ebi.ac.uk/efo/EFO_0004842 GCST90002297 Genome-wide genotyping array 11615 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Eosinophil counts 474,237 European ancestry individuals NA Affymetrix, Illumina [50000174] (imputed) 376 eosinophil count http://www.ebi.ac.uk/efo/EFO_0004842 GCST90002298 Genome-wide genotyping array 474237 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Eosinophil counts 86,890 East Asian ancestry individuals NA Affymetrix, Illumina [16279099] (imputed) 31 eosinophil count http://www.ebi.ac.uk/efo/EFO_0004842 GCST90002299 Genome-wide genotyping array 86890 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Eosinophil counts 2,966 Hispanic or Latin American individuals NA Affymetrix, Illumina [23758042] (imputed) 0 eosinophil count http://www.ebi.ac.uk/efo/EFO_0004842 GCST90002300 Genome-wide genotyping array 2966 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Eosinophil counts 8,142 South Asian ancestry individuals NA Affymetrix, Illumina [28445528] (imputed) 1 eosinophil count http://www.ebi.ac.uk/efo/EFO_0004842 GCST90002301 Genome-wide genotyping array 8142 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Eosinophil counts 583,850 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals NA Affymetrix, Illumina [19872809] (imputed) 346 eosinophil count http://www.ebi.ac.uk/efo/EFO_0004842 GCST90002302 Genome-wide genotyping array 583850 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Hematocrit 15,134 African American or Afro-Caribbean and African ancestry individuals NA Affymetrix, Illumina [36870619] (imputed) 1 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST90002303 Genome-wide genotyping array 15134 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Hematocrit 562,259 European ancestry individuals NA Affymetrix, Illumina [50640577] (imputed) 392 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST90002304 Genome-wide genotyping array 562259 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Hematocrit 142,940 East Asian ancestry individuals NA Affymetrix, Illumina [16289021] (imputed) 31 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST90002305 Genome-wide genotyping array 142940 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Hematocrit 9,301 Hispanic or Latin American individuals NA Affymetrix, Illumina [26810352] (imputed) 0 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST90002306 Genome-wide genotyping array 9301 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Hematocrit 8,189 South Asian ancestry individuals NA Affymetrix, Illumina [28493283] (imputed) 1 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST90002307 Genome-wide genotyping array 8189 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Hematocrit 737,823 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals NA Affymetrix, Illumina [24558453] (imputed) 356 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST90002308 Genome-wide genotyping array 737823 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Hemoglobin concentration 15,133 African American or Afro-Caribbean and African ancestry individuals NA Affymetrix, Illumina [36870618] (imputed) 2 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST90002309 Genome-wide genotyping array 15133 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Hemoglobin concentration 563,946 European ancestry individuals NA Affymetrix, Illumina [50638016] (imputed) 402 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST90002310 Genome-wide genotyping array 563946 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Hemoglobin concentration 149,861 East Asian ancestry individuals NA Affymetrix, Illumina [16709126] (imputed) 21 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST90002311 Genome-wide genotyping array 149861 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Hemoglobin concentration 9,302 Hispanic or Latin American individuals NA Affymetrix, Illumina [26810352] (imputed) 0 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST90002312 Genome-wide genotyping array 9302 2020-09-16 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Hemoglobin concentration 8,189 South Asian ancestry individuals NA Affymetrix, Illumina [28493177] (imputed) 2 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST90002313 Genome-wide genotyping array 8189 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Hemoglobin concentration 746,431 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals NA Affymetrix, Illumina [24653286] (imputed) 364 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST90002314 Genome-wide genotyping array 746431 2020-09-21 32888493 Chen MH 2020-09-01 Cell www.ncbi.nlm.nih.gov/pubmed/32888493 Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Lymphocyte counts 13,477 African American or Afro-Caribbean and African ancestry individuals NA Affymetrix, Illumina [36456147] (imputed) 2 lymphocyte count http://www.ebi.ac.uk/efo/EFO_0004587 GCST90002315 Genome-wide genotyping array 13477 2021-10-29 34356046 Oluwafemi OO 2021-07-01 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/34356046 Genome-Wide Association Studies of Conotruncal Heart Defects with Normally Related Great Vessels in the United States. Conotruncal heart defects with normally related great vessels in 22q.11.2 deletion syndrome 913 cases, 559 controls NA Affymetrix [3311160] (imputed) 5 Conotruncal heart malformations http://www.orpha.net/ORDO/Orphanet_2445 GCST90026409 Genome-wide genotyping array 1472 2021-10-29 34356046 Oluwafemi OO 2021-07-01 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/34356046 Genome-Wide Association Studies of Conotruncal Heart Defects with Normally Related Great Vessels in the United States. Conotruncal heart defects with normally related great vessels (without 22q.11.2 deletion syndrome) 294 European ancestry cases, 2,976 European ancestry controls, 641 trios NA Illumina [3311160] (imputed) 25 Conotruncal heart malformations http://www.orpha.net/ORDO/Orphanet_2445 GCST90026410 Genome-wide genotyping array 3911 2021-10-29 34356046 Oluwafemi OO 2021-07-01 Genes (Basel) www.ncbi.nlm.nih.gov/pubmed/34356046 Genome-Wide Association Studies of Conotruncal Heart Defects with Normally Related Great Vessels in the United States. Conotruncal heart defects with normally related great vessels 294 European ancestry cases, 2,976 European ancestry controls, 913 cases, 559 controls, 641 trios NA Affymetrix, Illumina [3311160] (imputed) 16 Conotruncal heart malformations http://www.orpha.net/ORDO/Orphanet_2445 GCST90026411 Genome-wide genotyping array 5383 2021-06-01 34002017 Shen S 2021-05-17 NPJ Precis Oncol www.ncbi.nlm.nih.gov/pubmed/34002017 A multi-omics study links TNS3 and SEPT7 to long-term former smoking NSCLC survival. Lung cancer prognosis in former smokers 1,299 European ancestry long-term former smokers NA Illumina [100680] 2 non-small cell lung carcinoma, disease prognosis measurement http://www.ebi.ac.uk/efo/EFO_0003060, http://www.ebi.ac.uk/efo/EFO_0007936 GCST90014045 Targeted genotyping array [Oncoarray] 1299 2021-09-09 34098431 Ning K 2021-04-20 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/34098431 Improving brain age estimates with deep learning leads to identification of novel genetic factors associated with brain aging. Relative brain age 16,998 European ancestry individuals NA NR [538476] 3 brain age measurement http://www.ebi.ac.uk/efo/EFO_0010602 GCST012361 Genome-wide genotyping array 16998 2021-09-27 33949668 Ma Y 2021-05-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33949668 Integrative Genomics Analysis Reveals a 21q22.11 Locus Contributing Risk to COVID-19. COVID-19 3,288 European ancestry cases, 676,840 European ancestry controls NA NR [8424883] (imputed) 3 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST012399 Genome-wide genotyping array 680128 2021-10-21 34177453 Swart PC 2021-06-10 Front Neurosci www.ncbi.nlm.nih.gov/pubmed/34177453 A Genome-Wide Association Study and Polygenic Risk Score Analysis of Posttraumatic Stress Disorder and Metabolic Syndrome in a South African Population. Post-traumatic stress disorder 260 South African Colored cases, 343 South African Colored controls NA Illumina [11927194] (imputed) 7 post-traumatic stress disorder http://www.ebi.ac.uk/efo/EFO_0001358 GCST90020063 Genome-wide genotyping array 603 2021-08-13 33055079 Boer CG 2020-10-14 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/33055079 Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify WNT9A as novel osteoarthritis gene. Hand osteoarthritis severity (hand Klsum) 4,829 Dutch ancestry individuals 1,203 individuals Illumina [10500000] (imputed) 2 osteoarthritis, hand http://www.ebi.ac.uk/efo/EFO_1000789 GCST90010716 Genome-wide genotyping array 4829 2021-08-13 33055079 Boer CG 2020-10-14 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/33055079 Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify WNT9A as novel osteoarthritis gene. Finger osteoarthritis severity (hand Klsum) 1,791 Dutch ancestry individuals 1,203 individuals Illumina [10500000] (imputed) 4 osteoarthritis, hand http://www.ebi.ac.uk/efo/EFO_1000789 GCST90010717 Genome-wide genotyping array 1791 2021-08-13 33055079 Boer CG 2020-10-14 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/33055079 Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify WNT9A as novel osteoarthritis gene. Thumb osteoarthritis severity (hand Klsum) 2,071 Dutch ancestry individuals 1,203 individuals Illumina [10500000] (imputed) 3 osteoarthritis, hand http://www.ebi.ac.uk/efo/EFO_1000789 GCST90010718 Genome-wide genotyping array 2071 2021-06-04 33359885 Gettler K 2020-12-24 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/33359885 Common and rare variant prediction and penetrance of IBD in a large, multi-ethnic, health system-based biobank cohort. Inflammatory bowel disease 15,507 European ancestry cases, 25,403 European ancestry controls, 2,345 African American cases, 5,002 African American controls NA NR [18368734] (imputed) 0 inflammatory bowel disease http://www.ebi.ac.uk/efo/EFO_0003767 GCST011786 Genome-wide genotyping array 48257 2021-07-07 34050200 Choi JW 2021-05-28 Sci Rep www.ncbi.nlm.nih.gov/pubmed/34050200 Genetically determined hypoalbuminemia as a risk factor for hypertension: instrumental variable analysis. Hypoalbuminemia 1,168 East Asian ancestry cases, 3,157 East Asian ancestry controls NA Affymetrix [519364] 4 Hypoalbuminemia http://purl.obolibrary.org/obo/HP_0003073 GCST012007 Genome-wide genotyping array 4325 2021-06-11 33987465 Alfradique-Dunham I 2021-01-28 Neurol Genet www.ncbi.nlm.nih.gov/pubmed/33987465 Genome-Wide Association Study Meta-Analysis for Parkinson Disease Motor Subtypes. Parkinson's disease motor subtype (tremor dominant vs postural instability/gait difficulty) 1,570 European ancestry tremor dominant cases, 1,259 European ancestry postural instability/gait difficulty cases NA Illumina [12910578] (imputed) 7 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST90000014 Genome-wide genotyping array 2829 2021-06-11 33987465 Alfradique-Dunham I 2021-01-28 Neurol Genet www.ncbi.nlm.nih.gov/pubmed/33987465 Genome-Wide Association Study Meta-Analysis for Parkinson Disease Motor Subtypes. Parkinson's disease motor subtype (tremor to postural instability/gait difficulty score ratio) 3,212 European ancestry individuals NA Illumina [14638245] (imputed) 31 Parkinson's disease symptom measurement http://www.ebi.ac.uk/efo/EFO_0600011 GCST90000015 Genome-wide genotyping array 3212 2021-09-29 34337522 van der Zanden LFM 2021-04-24 Eur Urol Open Sci www.ncbi.nlm.nih.gov/pubmed/34337522 CDH12 as a Candidate Gene for Kidney Injury in Posterior Urethral Valve Cases: A Genome-wide Association Study Among Patients with Obstructive Uropathies. Kidney injury 5 years post-surgery in obstructive uropathies 141 European ancestry cases, 216 European ancestry controls NA Illumina [622697] (imputed) 3 kidney injury http://www.ebi.ac.uk/efo/EFO_0009833 GCST90025931 Genome-wide genotyping array 357 2021-07-27 34211149 Mills MC 2021-07-01 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/34211149 Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour. Age at first sexual intercourse 214,547 European ancestry individuals NA NR [16567047] (imputed) 2 age at first sexual intercourse measurement http://www.ebi.ac.uk/efo/EFO_0009749 GCST90000045 Genome-wide genotyping array 214547 2021-07-27 34211149 Mills MC 2021-07-01 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/34211149 Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour. Age at first sexual intercourse 182,791 European ancestry individuals NA NR [16426330] (imputed) 8 age at first sexual intercourse measurement http://www.ebi.ac.uk/efo/EFO_0009749 GCST90000046 Genome-wide genotyping array 182791 2021-07-27 34211149 Mills MC 2021-07-01 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/34211149 Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour. Age at first sexual intercourse 397,338 European ancestry individuals NA NR [16516521] (imputed) 272 age at first sexual intercourse measurement http://www.ebi.ac.uk/efo/EFO_0009749 GCST90000047 Genome-wide genotyping array 397338 2021-07-27 34211149 Mills MC 2021-07-01 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/34211149 Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour. Age at first birth 418,758 European ancestry individuals NA NR [10813835] (imputed) 1 age at first birth measurement http://www.ebi.ac.uk/efo/EFO_0009101 GCST90000048 Genome-wide genotyping array 418758 2021-07-27 34211149 Mills MC 2021-07-01 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/34211149 Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour. Age at first birth 124,088 European ancestry individuals NA NR [9467402] (imputed) 1 age at first birth measurement http://www.ebi.ac.uk/efo/EFO_0009101 GCST90000049 Genome-wide genotyping array 124088 2021-07-27 34211149 Mills MC 2021-07-01 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/34211149 Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour. Age at first birth 542,901 European ancestry individuals NA NR [9744772] (imputed) 88 age at first birth measurement http://www.ebi.ac.uk/efo/EFO_0009101 GCST90000050 Genome-wide genotyping array 542901 2021-09-30 34045744 Levey DF 2021-05-27 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/34045744 Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions. Major depressive disorder 83,810 European ancestry cases, 166,405 European ancestry controls NA NR [NR] 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90020222 Genome-wide genotyping array 250215 2021-09-30 34045744 Levey DF 2021-05-27 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/34045744 Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions. Depression 55,228 European ancestry cases, 155,103 European ancestry controls NA NR [NR] 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90020223 Genome-wide genotyping array 210331 2021-09-30 34045744 Levey DF 2021-05-27 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/34045744 Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions. Depressive symptoms 169,546 European ancestry individuals NA NR [NR] 0 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST90020224 Genome-wide genotyping array 169546 2021-09-30 34045744 Levey DF 2021-05-27 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/34045744 Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions. Depressive symptoms 111,268 European ancestry individuals NA NR [NR] 0 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST90020225 Genome-wide genotyping array 111268 2021-09-30 34045744 Levey DF 2021-05-27 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/34045744 Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions. Major depressive disorder 25,843 African American cases, 33,757 African American controls NA NR [NR] 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90020226 Genome-wide genotyping array 59600 2021-09-30 34045744 Levey DF 2021-05-27 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/34045744 Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions. Major depressive disorder 340,591 European ancestry cases, 813,676 European ancestry controls 455,350 cases, 887,428 controls NR [NR] 117 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90020227 Genome-wide genotyping array 1154267 2021-09-30 34045744 Levey DF 2021-05-27 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/34045744 Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions. Depression 312,009 European ancestry cases, 802,374 European ancestry controls NA NR [NR] 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90020228 Genome-wide genotyping array 1114383 2021-09-30 34045744 Levey DF 2021-05-27 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/34045744 Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions. Depressive symptoms 286,821 European ancestry individuals NA NR [NR] 0 depressive symptom measurement http://www.ebi.ac.uk/efo/EFO_0007006 GCST90020229 Genome-wide genotyping array 286821 2021-09-30 34045744 Levey DF 2021-05-27 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/34045744 Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions. Major depressive disorder 340,591 European ancestry cases, 813,676 European ancestry controls, 25,843 African American cases, 33,757 African American controls NA NR [NR] 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90020230 Genome-wide genotyping array 1213867 2021-07-05 33239738 Didriksen M 2020-11-25 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33239738 Large genome-wide association study identifies three novel risk variants for restless legs syndrome. Restless legs syndrome 10,257 European ancestry cases, 470,725 European ancestry controls up to 15,126 European ancestry cases, up to 95,725 European ancestry controls Affymetrix, Illumina [15838848] (imputed) 25 restless legs syndrome http://www.ebi.ac.uk/efo/EFO_0004270 GCST011995 Genome-wide genotyping array 480982 2021-09-29 33904754 Cartwright R 2021-04-27 J Urol www.ncbi.nlm.nih.gov/pubmed/33904754 Genome Wide Association Study Identifies Two Novel Loci Associated with Female Stress and Urgency Urinary Incontinence. Urinary incontinence 2,942 European ancestry cases, 6,037 European ancestry controls 2,065 European ancestry cases, 2,004 European ancestry controls Illumina [9700000] (imputed) 2 Urinary incontinence http://purl.obolibrary.org/obo/HP_0000020 GCST90025928 Genome-wide genotyping array 8979 2021-09-29 33904754 Cartwright R 2021-04-27 J Urol www.ncbi.nlm.nih.gov/pubmed/33904754 Genome Wide Association Study Identifies Two Novel Loci Associated with Female Stress and Urgency Urinary Incontinence. Stress urinary incontinence 2,072 European ancestry cases, 6,907 European ancestry controls 1,321 European ancestry cases, 2,748 European ancestry controls Illumina [9700000] (imputed) 2 Stress urinary incontinence http://purl.obolibrary.org/obo/HP_0010992 GCST90025929 Genome-wide genotyping array 8979 2021-09-29 33904754 Cartwright R 2021-04-27 J Urol www.ncbi.nlm.nih.gov/pubmed/33904754 Genome Wide Association Study Identifies Two Novel Loci Associated with Female Stress and Urgency Urinary Incontinence. Urgency urinary incontinence 870 European ancestry cases, 8,109 European ancestry controls 744 European ancestry cases, 3,325 European ancestry controls Illumina [9700000] (imputed) 2 urgency urinary incontinence http://www.ebi.ac.uk/efo/EFO_0006865 GCST90025930 Genome-wide genotyping array 8979 2021-08-24 33331911 Freidin MB 2020-12-17 Rheumatology (Oxford) www.ncbi.nlm.nih.gov/pubmed/33331911 An association between chronic widespread pain and the gut microbiome. Coprococcus comes 3,521 European or unknown ancestry individuals NA NR [4841651] (imputed) 9 gut microbiome measurement http://www.ebi.ac.uk/efo/EFO_0007874 GCST90025871 Genome-wide genotyping array 3521 2021-08-24 33331911 Freidin MB 2020-12-17 Rheumatology (Oxford) www.ncbi.nlm.nih.gov/pubmed/33331911 An association between chronic widespread pain and the gut microbiome. Chronic widespread musculoskeletal pain up to 531 European or unknown ancestry cases, up to 2,742 European or unknown ancestry controls NA NR [4841651] (imputed) 15 chronic widespread pain http://www.ebi.ac.uk/efo/EFO_0010099 GCST90025872 Genome-wide genotyping array 3273 2021-09-03 34338756 Ahlberg G 2021-07-29 Eur Heart J www.ncbi.nlm.nih.gov/pubmed/34338756 Genome-wide association study identifies 18 novel loci associated with left atrial volume and function. Left atrial maximum volume 35,658 British ancestry individuals NA Affymetrix [10600000] (imputed) 2 NA NA GCST90025936 Genome-wide genotyping array 35658 2021-09-03 34338756 Ahlberg G 2021-07-29 Eur Heart J www.ncbi.nlm.nih.gov/pubmed/34338756 Genome-wide association study identifies 18 novel loci associated with left atrial volume and function. Left atrial minimum volume 35,658 British ancestry individuals NA Affymetrix [10600000] (imputed) 3 NA NA GCST90025937 Genome-wide genotyping array 35658 2021-09-03 34338756 Ahlberg G 2021-07-29 Eur Heart J www.ncbi.nlm.nih.gov/pubmed/34338756 Genome-wide association study identifies 18 novel loci associated with left atrial volume and function. Left atrial active emptying fraction 35,658 British ancestry individuals NA Affymetrix [10600000] (imputed) 6 left atrial function http://www.ebi.ac.uk/efo/EFO_0004294 GCST90025938 Genome-wide genotyping array 35658 2021-09-03 34338756 Ahlberg G 2021-07-29 Eur Heart J www.ncbi.nlm.nih.gov/pubmed/34338756 Genome-wide association study identifies 18 novel loci associated with left atrial volume and function. Left atrial passive emptying fraction 35,658 British ancestry individuals NA Affymetrix [10600000] (imputed) 2 left atrial function http://www.ebi.ac.uk/efo/EFO_0004294 GCST90025939 Genome-wide genotyping array 35658 2021-09-03 34338756 Ahlberg G 2021-07-29 Eur Heart J www.ncbi.nlm.nih.gov/pubmed/34338756 Genome-wide association study identifies 18 novel loci associated with left atrial volume and function. Left atrial total emptying fraction 35,658 British ancestry individuals NA Affymetrix [10600000] (imputed) 5 left atrial function http://www.ebi.ac.uk/efo/EFO_0004294 GCST90025940 Genome-wide genotyping array 35658 2021-09-06 33783510 Fatumo S 2021-03-30 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/33783510 Discovery and fine-mapping of kidney function loci in first genome-wide association study in Africans. Estimated glomerular filtration rate 3,288 Ugandan ancestry individuals 8,224 African American individuals Illumina [20594556] (imputed) 4 glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0005208 GCST90025873 Genome-wide genotyping array, Genome-wide sequencing 3288 2021-09-09 33888907 Shelton JF 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888907 Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. COVID-19 (covid vs negative) 9,913 European ancestry cases, 85,072 European ancestry controls, 2,553 Hispanic or Latin American cases, 13,086 Hispanic or Latin American controls, 506 Black or African American cases, 3,110 Black or African American controls NA Illumina [9939936] (imputed) 42 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST90027245 Genome-wide genotyping array 114240 2021-09-09 33888907 Shelton JF 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888907 Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. COVID-19 (hospitalized covid vs population) 613 European ancestry cases, 680,416 European ancestry controls, 140 Hispanic or Latin American cases, 94,327 Hispanic or Latin American controls, 49 Black or African American cases, 22,410 Black or African American controls NA Illumina [9875426] (imputed) 99 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST90027246 Genome-wide genotyping array 797955 2021-09-09 33888907 Shelton JF 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888907 Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. COVID-19 (covid pneumonia vs population) 1,004 European ancestry cases, 680,354 European ancestry controls, 218 Hispanic or Latin American cases, 94,318 Hispanic or Latin American controls, 64 Black or African American cases, 22,412 Black or African American controls NA Illumina [9901720] (imputed) 73 pneumonia, COVID-19 http://www.ebi.ac.uk/efo/EFO_0003106, http://purl.obolibrary.org/obo/MONDO_0100096 GCST90027247 Genome-wide genotyping array 798370 2021-09-09 33888907 Shelton JF 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888907 Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. COVID-19 (covid respiratory support vs population) 495 European ancestry cases, 680,440 European ancestry controls, 102 Hispanic or Latin American cases, 94,330 Hispanic or Latin American controls, 39 Black or African American cases, 22,410 Black or African American controls NA Illumina [9842460] (imputed) 84 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST90027248 Genome-wide genotyping array 797816 2021-09-09 33888907 Shelton JF 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888907 Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. COVID-19 (severe respiratory symptoms vs population) 1,128 European ancestry cases, 679,531 European ancestry controls, 245 Hispanic or Latin American cases, 94,237 Hispanic or Latin American controls, 74 Black or African American cases, 22,383 Black or African American controls NA Illumina [9906551] (imputed) 52 pneumonia, COVID-19 http://www.ebi.ac.uk/efo/EFO_0003106, http://purl.obolibrary.org/obo/MONDO_0100096 GCST90027249 Genome-wide genotyping array 797598 2021-09-09 33888907 Shelton JF 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888907 Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. COVID-19 (covid vs negative) 9,913 European ancestry cases, 85,072 European ancestry controls NA Illumina [31704722] (imputed) 2 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST90027250 Genome-wide genotyping array 94985 2021-09-09 33888907 Shelton JF 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888907 Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. COVID-19 (hospitalized covid vs population) 613 European ancestry cases, 680,416 European ancestry controls NA Illumina [21433846] (imputed) 2 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST90027251 Genome-wide genotyping array 681029 2021-09-09 33888907 Shelton JF 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888907 Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. COVID-19 (covid pneumonia vs population) 1,004 European ancestry cases, 680,354 European ancestry controls NA Illumina [23640711] (imputed) 1 pneumonia, COVID-19 http://www.ebi.ac.uk/efo/EFO_0003106, http://purl.obolibrary.org/obo/MONDO_0100096 GCST90027252 Genome-wide genotyping array 681358 2021-09-09 33888907 Shelton JF 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888907 Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. COVID-19 (covid respiratory support vs population) 495 European ancestry cases, 680,440 European ancestry controls NA Illumina [20506675] (imputed) 1 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST90027253 Genome-wide genotyping array 680935 2021-09-09 33888907 Shelton JF 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888907 Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. COVID-19 (severe respiratory symptoms vs population) 1,128 European ancestry cases, 679,531 European ancestry controls NA Illumina [2412076] (imputed) 1 pneumonia, COVID-19 http://www.ebi.ac.uk/efo/EFO_0003106, http://purl.obolibrary.org/obo/MONDO_0100096 GCST90027254 Genome-wide genotyping array 680659 2021-09-09 33888907 Shelton JF 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888907 Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. COVID-19 (covid vs negative) 2,553 Hispanic or Latin American cases, 13,086 Hispanic or Latin American controls NA Illumina [35218582] (imputed) 1 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST90027255 Genome-wide genotyping array 15639 2021-09-09 33888907 Shelton JF 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888907 Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. COVID-19 (hospitalized covid vs population) 140 Hispanic or Latin American cases, 94,327 Hispanic or Latin American controls NA Illumina [20840951] (imputed) 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST90027256 Genome-wide genotyping array 94467 2021-09-09 33888907 Shelton JF 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888907 Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. COVID-19 (covid pneumonia vs population) 218 Hispanic or Latin American cases, 94,318 Hispanic or Latin American controls NA Illumina [23268376] (imputed) 0 pneumonia, COVID-19 http://www.ebi.ac.uk/efo/EFO_0003106, http://purl.obolibrary.org/obo/MONDO_0100096 GCST90027257 Genome-wide genotyping array 94536 2021-09-09 33888907 Shelton JF 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888907 Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. COVID-19 (covid respiratory support vs population) 102 Hispanic or Latin American cases, 94,330 Hispanic or Latin American controls NA Illumina [19031602] (imputed) 1 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST90027258 Genome-wide genotyping array 94432 2021-09-09 33888907 Shelton JF 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888907 Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. COVID-19 (severe respiratory symptoms vs population) 245 Hispanic or Latin American cases, 94,237 Hispanic or Latin American controls NA Illumina [2397628] (imputed) 0 pneumonia, COVID-19 http://www.ebi.ac.uk/efo/EFO_0003106, http://purl.obolibrary.org/obo/MONDO_0100096 GCST90027259 Genome-wide genotyping array 94482 2021-09-09 33888907 Shelton JF 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888907 Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. COVID-19 (covid vs negative) 506 Black or African American cases, 3,110 Black or African American controls NA Illumina [31623562] (imputed) 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST90027260 Genome-wide genotyping array 3616 2021-09-09 33888907 Shelton JF 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888907 Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. COVID-19 (hospitalized covid vs population) 49 Black or African American cases, 22,410 Black or African American controls NA Illumina [21980587] (imputed) 0 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST90027261 Genome-wide genotyping array 22459 2021-09-09 33888907 Shelton JF 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888907 Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. COVID-19 (covid pneumonia vs population) 64 Black or African American cases, 22,412 Black or African American controls NA Illumina [23342614] (imputed) 0 pneumonia, COVID-19 http://www.ebi.ac.uk/efo/EFO_0003106, http://purl.obolibrary.org/obo/MONDO_0100096 GCST90027262 Genome-wide genotyping array 22476 2021-09-09 33888907 Shelton JF 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888907 Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. COVID-19 (covid respiratory support vs population) 39 Black or African American cases, 22,410 Black or African American controls NA Illumina [20847880] (imputed) 1 COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096 GCST90027263 Genome-wide genotyping array 22449 2021-09-09 33888907 Shelton JF 2021-04-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33888907 Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity. COVID-19 (severe respiratory symptoms vs population) 74 Black or African American cases, 22,383 Black or African American controls NA Illumina [24042173] (imputed) 0 pneumonia, COVID-19 http://www.ebi.ac.uk/efo/EFO_0003106, http://purl.obolibrary.org/obo/MONDO_0100096 GCST90027264 Genome-wide genotyping array 22457 2021-10-08 34548389 Yu Z 2021-09-21 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/34548389 Polygenic Risk Scores for Kidney Function and Their Associations with Circulating Proteome, and Incident Kidney Diseases. Estimated glomerular filtration rate (creatinine) 949,116 European ancestry individuals, 166,997 East Asian ancestry individuals, 21,338 South Asian ancestry individuals, 17,459 African American individuals, 4,961 Hispanic individuals NA Affymetrix, Illumina [8439544] (imputed) 0 creatinine measurement, glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0005208 GCST90026654 Genome-wide genotyping array 1159871 2021-10-15 34560606 Park S 2021-09-09 Clin Nutr www.ncbi.nlm.nih.gov/pubmed/34560606 Association between polygenetic risk scores related to sarcopenia risk and their interactions with regular exercise in a large cohort of Korean adults. sarcopenia 1,368 Korean ancestry cases, 15,742 Korean ancestry controls NA Affymetrix [NR] 2 sarcopenia http://www.ebi.ac.uk/efo/EFO_1000653 GCST90044764 Genome-wide genotyping array 17110 2021-07-27 34101054 Nikopensius T 2021-06-08 Clin Rheumatol www.ncbi.nlm.nih.gov/pubmed/34101054 Association analysis of juvenile idiopathic arthritis genetic susceptibility factors in Estonian patients. Arthritis (juvenile idiopathic) 263 Estonian ancestry cases, 6,956 Estonian ancestry controls NA Illumina [16583468] (imputed) 2 juvenile idiopathic arthritis http://www.ebi.ac.uk/efo/EFO_0002609 GCST012103 Genome-wide genotyping array 7219 2021-07-27 34101054 Nikopensius T 2021-06-08 Clin Rheumatol www.ncbi.nlm.nih.gov/pubmed/34101054 Association analysis of juvenile idiopathic arthritis genetic susceptibility factors in Estonian patients. Arthritis (oligoarticular juvenile idiopathic) Up to 263 Estonian ancestry cases, up to 6,956 Estonian ancestry controls NA Illumina [up to 16583468] (imputed) 1 oligoarticular juvenile idiopathic arthritis http://www.ebi.ac.uk/efo/EFO_1002019 GCST012102 Genome-wide genotyping array 7219 2021-10-08 34155719 Margaritte-Jeannin P 2021-06-22 Clin Exp Allergy www.ncbi.nlm.nih.gov/pubmed/34155719 Identification of OCA2 as a novel locus for the co-morbidity of asthma-plus-eczema. Asthma and eczema 1,208 European ancestry cases with both asthma and eczema, 7,599 European ancestry controls with neither asthma nor eczema NA Illumina [NR] (imputed) 4 Eczema, asthma http://purl.obolibrary.org/obo/HP_0000964, http://www.ebi.ac.uk/efo/EFO_0000270 GCST012462 Genome-wide genotyping array 8807 2021-10-01 33948810 Gurinovich A 2021-05-04 Geroscience www.ncbi.nlm.nih.gov/pubmed/33948810 Effect of longevity genetic variants on the molecular aging rate. Longevity (100 years and older) 1,320 European ancestry cases, 2,899 European ancestry controls 312 Ashkenazi Jewish ancestry cases, 638 Ashkenazi Jewish ancestry controls Illumina [9039731] (imputed) 8 longevity http://www.ebi.ac.uk/efo/EFO_0004300 GCST012419 Genome-wide genotyping array 4219 2021-08-13 34308111 Amin HA 2021-01-07 BMJ Nutr Prev Health www.ncbi.nlm.nih.gov/pubmed/34308111 No evidence that vitamin D is able to prevent or affect the severity of COVID-19 in individuals with European ancestry: a Mendelian randomisation study of open data. Vitamin D insufficiency 35,079 European ancestry cases, 140,898 European ancestry controls NA Affymetrix [812428] 17 vitamin D deficiency http://www.ebi.ac.uk/efo/EFO_0003762 GCST90020244 Genome-wide genotyping array 175977 2021-10-06 34154648 Kim HR 2021-06-21 Alzheimers Res Ther www.ncbi.nlm.nih.gov/pubmed/34154648 Identifying novel genetic variants for brain amyloid deposition: a genome-wide association study in the Korean population. Amyloid beta positivity 629 Korean ancestry cases, 561 Korean ancestry controls 104 Korean ancestry cases, 180 Korean ancestry controls Illumina [4906407] (imputed) 4 amyloid-beta measurement http://www.ebi.ac.uk/efo/EFO_0005194 GCST012459 Genome-wide genotyping array 1190 2021-07-15 31819081 Rivera NV 2019-12-09 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31819081 A Gene-Environment Interaction Between Smoking and Gene polymorphisms Provides a High Risk of Two Subgroups of Sarcoidosis. Sarcoidosis (non-Lofgren's syndrome) (smoking status interaction) 230 European ancestry never smoker cases, 225 European ancestry ever smoker cases, 1,349 European ancestry never smoker controls, 1,617 European ancestry ever smoker controls NA Illumina [186000] 0 Sarcoidosis http://www.orpha.net/ORDO/Orphanet_797 GCST012029 Targeted genotyping array [ImmunoChip] 3421 2021-07-15 31819081 Rivera NV 2019-12-09 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31819081 A Gene-Environment Interaction Between Smoking and Gene polymorphisms Provides a High Risk of Two Subgroups of Sarcoidosis. Sarcoidosis (Lofgren's syndrome) (smoking status interaction) 155 European ancestry never smoker cases, 137 European ancestry ever smoker cases, 1,349 European ancestry never smoker controls, 1,617 European ancestry ever smoker controls NA Illumina [186000] 0 Sarcoidosis http://www.orpha.net/ORDO/Orphanet_797 GCST012030 Targeted genotyping array [ImmunoChip] 3258 2021-10-15 34337005 Duan H 2021-07-17 Biomed Res Int www.ncbi.nlm.nih.gov/pubmed/34337005 A Genome-Wide Association Study of Age-Related Hearing Impairment in Middle- and Old-Aged Chinese Twins. Hearing function (0.5 kHz) 131 Chinese ancestry dizygotic twin pairs NA Illumina [1365315] 7 hearing threshold measurement, hearing measurement http://www.ebi.ac.uk/efo/EFO_0007618, http://www.ebi.ac.uk/efo/EFO_0007616 GCST90027021 Genome-wide genotyping array 131 2021-10-15 34337005 Duan H 2021-07-17 Biomed Res Int www.ncbi.nlm.nih.gov/pubmed/34337005 A Genome-Wide Association Study of Age-Related Hearing Impairment in Middle- and Old-Aged Chinese Twins. Hearing function (1 kHz) 131 Chinese ancestry dizygotic twin pairs NA Illumina [1365315] 5 hearing threshold measurement, hearing measurement http://www.ebi.ac.uk/efo/EFO_0007618, http://www.ebi.ac.uk/efo/EFO_0007616 GCST90027022 Genome-wide genotyping array 131 2021-10-15 34337005 Duan H 2021-07-17 Biomed Res Int www.ncbi.nlm.nih.gov/pubmed/34337005 A Genome-Wide Association Study of Age-Related Hearing Impairment in Middle- and Old-Aged Chinese Twins. Hearing function (2 kHz) 131 Chinese ancestry dizygotic twin pairs NA Illumina [1365315] 14 hearing threshold measurement, hearing measurement http://www.ebi.ac.uk/efo/EFO_0007618, http://www.ebi.ac.uk/efo/EFO_0007616 GCST90027023 Genome-wide genotyping array 131 2021-10-15 34337005 Duan H 2021-07-17 Biomed Res Int www.ncbi.nlm.nih.gov/pubmed/34337005 A Genome-Wide Association Study of Age-Related Hearing Impairment in Middle- and Old-Aged Chinese Twins. Hearing function (4 kHz) 131 Chinese ancestry dizygotic twin pairs NA Illumina [1365315] 5 hearing threshold measurement, hearing measurement http://www.ebi.ac.uk/efo/EFO_0007618, http://www.ebi.ac.uk/efo/EFO_0007616 GCST90027024 Genome-wide genotyping array 131 2021-10-15 34337005 Duan H 2021-07-17 Biomed Res Int www.ncbi.nlm.nih.gov/pubmed/34337005 A Genome-Wide Association Study of Age-Related Hearing Impairment in Middle- and Old-Aged Chinese Twins. Hearing function (8 kHz) 131 Chinese ancestry dizygotic twin pairs NA Illumina [1365315] 9 hearing threshold measurement, hearing measurement http://www.ebi.ac.uk/efo/EFO_0007618, http://www.ebi.ac.uk/efo/EFO_0007616 GCST90027025 Genome-wide genotyping array 131 2021-10-15 34337005 Duan H 2021-07-17 Biomed Res Int www.ncbi.nlm.nih.gov/pubmed/34337005 A Genome-Wide Association Study of Age-Related Hearing Impairment in Middle- and Old-Aged Chinese Twins. Hearing function 131 Chinese ancestry dizygotic twin pairs NA Illumina [1365315] 4 hearing threshold measurement, pure tone hearing measurement http://www.ebi.ac.uk/efo/EFO_0007618, http://www.ebi.ac.uk/efo/EFO_0007617 GCST90027026 Genome-wide genotyping array 131 2021-10-08 34162658 Quinn MC 2021-06-23 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/34162658 Identification of a locus near ULK1 associated with progression-free survival in ovarian cancer. Progression free survival in epithelial ovarian cancer treated with carboplatin and paclitaxel 2,352 European ancestry individuals NA Illumina [12764477] (imputed) 34 progression free survival, response to carboplatin, ovarian carcinoma, response to paclitaxel http://www.ebi.ac.uk/efo/EFO_0004920, http://purl.obolibrary.org/obo/GO_0097328, http://www.ebi.ac.uk/efo/EFO_0001075, http://purl.obolibrary.org/obo/GO_1901555 GCST012474 Genome-wide genotyping array 2352 2021-10-08 34162658 Quinn MC 2021-06-23 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/34162658 Identification of a locus near ULK1 associated with progression-free survival in ovarian cancer. Progression free survival in epithelial ovarian cancer 5,596 European ancestry individuals NA Illumina [12770451] (imputed) 19 progression free survival, ovarian carcinoma http://www.ebi.ac.uk/efo/EFO_0004920, http://www.ebi.ac.uk/efo/EFO_0001075 GCST012473 Genome-wide genotyping array 5596 2021-10-08 34162658 Quinn MC 2021-06-23 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/34162658 Identification of a locus near ULK1 associated with progression-free survival in ovarian cancer. Progression free survival in serous epithelial ovarian cancer treated with carboplatin and paclitaxel 1,751 European ancestry individuals NA Illumina [12759548] (imputed) 36 progression free survival, response to carboplatin, ovarian serous carcinoma, response to paclitaxel http://www.ebi.ac.uk/efo/EFO_0004920, http://purl.obolibrary.org/obo/GO_0097328, http://www.ebi.ac.uk/efo/EFO_1001516, http://purl.obolibrary.org/obo/GO_1901555 GCST012472 Genome-wide genotyping array 1751 2021-10-08 34162658 Quinn MC 2021-06-23 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/34162658 Identification of a locus near ULK1 associated with progression-free survival in ovarian cancer. Progression free survival in serous epithelial ovarian cancer 4,037 European ancestry individuals NA Illumina [12770451] (imputed) 23 progression free survival, ovarian serous carcinoma http://www.ebi.ac.uk/efo/EFO_0004920, http://www.ebi.ac.uk/efo/EFO_1001516 GCST012471 Genome-wide genotyping array 4037 2021-10-08 34162658 Quinn MC 2021-06-23 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/34162658 Identification of a locus near ULK1 associated with progression-free survival in ovarian cancer. Overall survival in epithelial ovarian cancer treated with carboplatin and paclitaxel 2,620 European ancestry individuals NA Illumina [12765645] (imputed) 0 response to carboplatin, overall survival, ovarian carcinoma, response to paclitaxel http://purl.obolibrary.org/obo/GO_0097328, http://www.ebi.ac.uk/efo/EFO_0000638, http://www.ebi.ac.uk/efo/EFO_0001075, http://purl.obolibrary.org/obo/GO_1901555 GCST012470 Genome-wide genotyping array 2620 2021-10-08 34162658 Quinn MC 2021-06-23 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/34162658 Identification of a locus near ULK1 associated with progression-free survival in ovarian cancer. Overall survival in epithelial ovarian cancer 6,160 European ancestry individuals NA Illumina [12770750] (imputed) 0 overall survival, ovarian carcinoma http://www.ebi.ac.uk/efo/EFO_0000638, http://www.ebi.ac.uk/efo/EFO_0001075 GCST012469 Genome-wide genotyping array 6160 2021-10-08 34162658 Quinn MC 2021-06-23 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/34162658 Identification of a locus near ULK1 associated with progression-free survival in ovarian cancer. Overall survival in serous epithelial ovarian cancer treated with paclitaxel and cisplatin 1,901 European ancestry individuals NA Illumina [12761635] (imputed) 0 response to carboplatin, overall survival, ovarian serous carcinoma, response to paclitaxel http://purl.obolibrary.org/obo/GO_0097328, http://www.ebi.ac.uk/efo/EFO_0000638, http://www.ebi.ac.uk/efo/EFO_1001516, http://purl.obolibrary.org/obo/GO_1901555 GCST012468 Genome-wide genotyping array 1901 2021-10-08 34162658 Quinn MC 2021-06-23 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/34162658 Identification of a locus near ULK1 associated with progression-free survival in ovarian cancer. Overall survival in serous epithelial ovarian cancer 4,391 European ancestry individuals NA Illumina [12769717] (imputed) 0 overall survival, ovarian serous carcinoma http://www.ebi.ac.uk/efo/EFO_0000638, http://www.ebi.ac.uk/efo/EFO_1001516 GCST012467 Genome-wide genotyping array 4391 2021-09-08 33838163 Luo S 2021-04-07 Kidney Int www.ncbi.nlm.nih.gov/pubmed/33838163 Genome-wide association study of serum metabolites in the African American Study of Kidney Disease and Hypertension. Serum metabolite concentrations in chronic kidney disease 619 African American individuals NA Illumina [14760605] (imputed) 42 serum metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005653 GCST012353 Genome-wide genotyping array 619 2021-06-09 33972514 Pazoki R 2021-05-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33972514 Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes. Liver enzyme levels (alanine transaminase) 437,267 European ancestry individuals 315,572 European ancestry individuals Affymetrix [13995440] (imputed) 150 serum alanine aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004735 GCST90013405 Genome-wide genotyping array 437267 2021-06-09 33972514 Pazoki R 2021-05-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33972514 Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes. Liver enzyme levels (alkaline phosphatase) 437,438 European ancestry individuals 315,572 European ancestry individuals Affymetrix [13995440] (imputed) 290 alkaline phosphatase measurement http://www.ebi.ac.uk/efo/EFO_0004533 GCST90013406 Genome-wide genotyping array 437438 2021-06-09 33972514 Pazoki R 2021-05-10 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33972514 Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes. Liver enzyme levels (gamma-glutamyl transferase) 437,194 European ancestry individuals 315,572 European ancestry individuals Affymetrix [13995440] (imputed) 200 serum gamma-glutamyl transferase measurement http://www.ebi.ac.uk/efo/EFO_0004532 GCST90013407 Genome-wide genotyping array 437194 2021-04-27 33514426 Tan LK 2021-01-30 Arthritis Res Ther www.ncbi.nlm.nih.gov/pubmed/33514426 The spectrum of association in HLA region with rheumatoid arthritis in a diverse Asian population: evidence from the MyEIRA case-control study. Rheumatoid arthritis 530 Malay ancestry cases, 259 Chinese ancestry cases, 412 Asian Indian ancestry cases, 59 cases, 981 Malay ancestry controls, 205 Chinese ancestry controls, 297 Asian Indian controls, 87 controls NA Illumina [113576] 1 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST011558 Targeted genotyping array [ImmunoChip] 2830 2021-04-27 33514426 Tan LK 2021-01-30 Arthritis Res Ther www.ncbi.nlm.nih.gov/pubmed/33514426 The spectrum of association in HLA region with rheumatoid arthritis in a diverse Asian population: evidence from the MyEIRA case-control study. Rheumatoid arthritis (ACPA-positive) 530 Malay ancestry cases, 259 Chinese ancestry cases, 412 Asian Indian ancestry cases, 59 cases, 981 Malay ancestry controls, 205 Chinese ancestry controls, 297 Asian Indian controls, 87 controls NA Illumina [113576] 1 ACPA-positive rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0009459 GCST011557 Targeted genotyping array [ImmunoChip] 2830 2021-04-27 33514426 Tan LK 2021-01-30 Arthritis Res Ther www.ncbi.nlm.nih.gov/pubmed/33514426 The spectrum of association in HLA region with rheumatoid arthritis in a diverse Asian population: evidence from the MyEIRA case-control study. Rheumatoid arthritis (ACPA-negative) 530 Malay ancestry cases, 259 Chinese ancestry cases, 412 Asian Indian ancestry cases, 59 cases, 981 Malay ancestry controls, 205 Chinese ancestry controls, 297 Asian Indian controls, 87 controls NA Illumina [113576] 1 ACPA-negative rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0009460 GCST011556 Targeted genotyping array [ImmunoChip] 2830 2021-03-01 33096046 Johnson EC 2020-10-20 Lancet Psychiatry www.ncbi.nlm.nih.gov/pubmed/33096046 A large-scale genome-wide association study meta-analysis of cannabis use disorder. Cannabis use disorder 17,068 European ancestry cases, 357,219 European ancestry controls, 3,848 African ancestry cases, 5,897 African ancestry controls NA Illumina [NR] (imputed) 4 cannabis dependence http://www.ebi.ac.uk/efo/EFO_0007191 GCST011179 Genome-wide genotyping array 384032 2021-05-26 33093117 Yan Q 2020-10-22 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/33093117 A genome-wide association study of severe asthma exacerbations in Latino children and adolescents. Severe exacerbations in childhood asthma 2,509 Latino cases, 1,501 Latino controls NA Affymetrix, Illumina [~ 6000000] (imputed) 2 asthma exacerbation measurement http://www.ebi.ac.uk/efo/EFO_0007614 GCST011737 Genome-wide genotyping array 4010 2021-07-20 33080986 Furukawa K 2020-10-18 Nutrients www.ncbi.nlm.nih.gov/pubmed/33080986 A Genome-Wide Association Study Identifies the Association between the 12q24 Locus and Black Tea Consumption in Japanese Populations. Tea consumption 12,140 Japanese ancestry individuals 118 Japanese ancestry individuals Illumina [5256047] (imputed) 6 tea consumption measurement http://www.ebi.ac.uk/efo/EFO_0010091 GCST012044 Genome-wide genotyping array 12140 2021-06-17 33243845 Strausz S 2020-11-26 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/33243845 Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health. Obstructive sleep apnea 16,761 Finnish ancestry cases, 201,194 Finnish ancestry controls 10,348 European or unknown ancestry cases, 474,608 European or unknown ancestry controls Affymetrix, Illumina [NR] (imputed) 1 obstructive sleep apnea http://www.ebi.ac.uk/efo/EFO_0003918 GCST011922 Genome-wide genotyping array 217955 2021-06-17 33243845 Strausz S 2020-11-26 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/33243845 Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health. Obstructive sleep apnea (BMI adjusted) 12,759 Finnish ancestry cases, 146,972 Finnish ancestry controls NR Affymetrix, Illumina [NR] (imputed) 2 obstructive sleep apnea http://www.ebi.ac.uk/efo/EFO_0003918 GCST011921 Genome-wide genotyping array 159731 2020-11-04 33097823 Pei YF 2020-10-23 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33097823 The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study. Appendicular lean mass 450,243 European ancestry individuals NA Affymetrix [18391927] (imputed) 212 appendicular lean mass http://www.ebi.ac.uk/efo/EFO_0004980 GCST90000025 Genome-wide genotyping array 450243 2020-11-04 33097823 Pei YF 2020-10-23 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33097823 The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study. Appendicular lean mass 205,513 European ancestry men NA Affymetrix [18391927] (imputed) 46 appendicular lean mass http://www.ebi.ac.uk/efo/EFO_0004980 GCST90000026 Genome-wide genotyping array 205513 2020-11-04 33097823 Pei YF 2020-10-23 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33097823 The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study. Appendicular lean mass 244,730 European ancestry women NA Affymetrix [18391927] (imputed) 50 appendicular lean mass http://www.ebi.ac.uk/efo/EFO_0004980 GCST90000027 Genome-wide genotyping array 244730 2020-12-10 32959083 Adewuyi EO 2020-09-21 Hum Genet www.ncbi.nlm.nih.gov/pubmed/32959083 Genetic analysis of endometriosis and depression identifies shared loci and implicates causal links with gastric mucosa abnormality. Endometriosis or depression (pleiotropy) 17,054 endometriosis cases, 170,756 European ancestry depression cases, 191,858 controls, 329,443 European ancestry controls NA NR [6694342] 31 endometriosis, unipolar depression http://www.ebi.ac.uk/efo/EFO_0001065, http://www.ebi.ac.uk/efo/EFO_0003761 GCST010859 Genome-wide genotyping array 709111 2021-06-08 33219367 Li W 2020-11-20 Prostate Cancer Prostatic Dis www.ncbi.nlm.nih.gov/pubmed/33219367 Genome-wide association study identifies a role for the progesterone receptor in benign prostatic hyperplasia risk. Benign prostatic hyperplasia 1,942 cases, 4,730 controls 5,109 cases, 161,911 controls NR [5474821] (imputed) 0 benign prostatic hyperplasia http://www.ebi.ac.uk/efo/EFO_0000284 GCST011827 Genome-wide genotyping array 6672 2021-10-11 33794208 Bowden SJ 2021-04-01 Lancet Oncol www.ncbi.nlm.nih.gov/pubmed/33794208 Genetic variation in cervical preinvasive and invasive disease: a genome-wide association study. Cervical intraepithelial neoplasia grade 3 4,005 European ancestry cases, 145,545 European ancestry controls NA Affymetrix [9600464] (imputed) 2 Cervical Intraepithelial Neoplasia Grade 2/3 http://www.ebi.ac.uk/efo/EFO_1000166 GCST012476 Genome-wide genotyping array 149550 2021-10-11 33794208 Bowden SJ 2021-04-01 Lancet Oncol www.ncbi.nlm.nih.gov/pubmed/33794208 Genetic variation in cervical preinvasive and invasive disease: a genome-wide association study. Invasive cervical cancer 764 European ancestry cases, 145,545 European ancestry controls NA Affymetrix [9600464] (imputed) 2 cervical carcinoma http://www.ebi.ac.uk/efo/EFO_0001061 GCST012477 Genome-wide genotyping array 146309 2021-10-11 33794208 Bowden SJ 2021-04-01 Lancet Oncol www.ncbi.nlm.nih.gov/pubmed/33794208 Genetic variation in cervical preinvasive and invasive disease: a genome-wide association study. Cervical intraepithelial neoplasia grade 3 and invasive cervical cancer 764 European ancestry invasive cervical cancer cases, 4,005 European ancestry cervical intraepithelial neoplasia grade 3 cases, 145,545 European ancestry controls NA Affymetrix [9600464] (imputed) 6 cervical carcinoma, Cervical Intraepithelial Neoplasia Grade 2/3 http://www.ebi.ac.uk/efo/EFO_0001061, http://www.ebi.ac.uk/efo/EFO_1000166 GCST012475 Genome-wide genotyping array 150317 2021-04-06 33772158 Hoggart C 2021-03-26 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/33772158 Identification of novel locus associated with coronary artery aneurysms and validation of loci for susceptibility to Kawasaki disease. Kawasaki disease 400 European ancestry cases, 6,101 European ancestry controls 346 European ancestry cases, 1,609 European ancestry controls Illumina [5784964] (imputed) 8 mucocutaneous lymph node syndrome http://www.ebi.ac.uk/efo/EFO_0004246 GCST90013537 Genome-wide genotyping array 6501 2021-04-06 33772158 Hoggart C 2021-03-26 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/33772158 Identification of novel locus associated with coronary artery aneurysms and validation of loci for susceptibility to Kawasaki disease. Coronary artery aneurysm in Kawasaki disease 200 European ancestry cases, 276 European ancestry controls NA Illumina [4873589] (imputed) 6 coronary aneurysm http://www.ebi.ac.uk/efo/EFO_1000881 GCST90013538 Genome-wide genotyping array 476 2021-04-27 33766035 Wakim V 2021-03-25 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/33766035 New susceptibility alleles associated with severe coronary artery stenosis in the Lebanese population. Severe coronary stenosis (family history of CAD interaction) 1,734 Middle Eastern ancestry cases, 757 Middle Eastern ancestry controls NA Illumina [NR] 1 coronary stenosis, family history http://www.ebi.ac.uk/efo/EFO_1000882, http://www.ebi.ac.uk/efo/EFO_0000493 GCST011565 Genome-wide genotyping array 2491 2021-04-27 33766035 Wakim V 2021-03-25 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/33766035 New susceptibility alleles associated with severe coronary artery stenosis in the Lebanese population. Severe coronary stenosis (young age of onset interaction) 1,734 Middle Eastern ancestry cases, 757 Middle Eastern ancestry controls NA Illumina [NR] 4 age at onset, coronary stenosis http://www.ebi.ac.uk/efo/EFO_0004847, http://www.ebi.ac.uk/efo/EFO_1000882 GCST011564 Genome-wide genotyping array 2491 2021-04-27 33766035 Wakim V 2021-03-25 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/33766035 New susceptibility alleles associated with severe coronary artery stenosis in the Lebanese population. Severe coronary stenosis 1,734 Middle Eastern ancestry cases, 757 Middle Eastern ancestry controls NA Illumina [NR] 2 coronary stenosis http://www.ebi.ac.uk/efo/EFO_1000882 GCST011566 Genome-wide genotyping array 2491 2020-09-28 30535219 Choi SH 2018-12-01 JAMA www.ncbi.nlm.nih.gov/pubmed/30535219 Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation. Early onset atrial fibrillation 2,781 European ancestry cases, 4,959 European ancestry controls NA NR [8248975] 0 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST010636 Genome-wide sequencing 7740 2021-09-02 33783297 Zai CC 2021-03-30 World J Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/33783297 Genome-wide association study of suicidal behaviour severity in mood disorders. Suicide attempt severity in mood disorders 719 European ancestry bipolar disorder cases, 2,787 European ancestry major depressive disorder cases NA Illumina [6737359] (imputed) 17 suicide behaviour measurement http://www.ebi.ac.uk/efo/EFO_0006882 GCST012279 Genome-wide genotyping array 3506 2021-09-02 33783297 Zai CC 2021-03-30 World J Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/33783297 Genome-wide association study of suicidal behaviour severity in mood disorders. Suicidality in mood disorders 719 European ancestry bipolar disorder cases, 2,787 European ancestry major depressive disorder cases NA Illumina [6737359] (imputed) 8 suicide behaviour measurement http://www.ebi.ac.uk/efo/EFO_0006882 GCST012280 Genome-wide genotyping array 3506 2021-09-01 33782385 Andlauer TFM 2021-03-29 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/33782385 Genetic factors influencing a neurobiological substrate for psychiatric disorders. Common neurobiological substrate measurement (PC1) 2,271 individuals 865 individuals Affymetrix, Illumina [up to 8620154] (imputed) 1 grey matter volume measurement http://www.ebi.ac.uk/efo/EFO_0005420 GCST012278 Genome-wide genotyping array 2271 2021-04-30 33310085 Emdin CA 2020-12-10 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/33310085 Association of genetic variation with cirrhosis: a multi-trait genome-wide association and gene-environment interaction study. Cirrhosis (multi-trait analysis) 4,829 European, African, Asian and unknown ancestry cases, 72,705 European, African, Asian and unknown ancestry controls, 362,539 European, African, Asian and unknown ancestry individuals with ALT measurements 3,554 European, African, Asian and unknown ancestry cases, 343,286 European, African, Asian and unknown ancestry controls Affymetrix, Illumina [3163456] (imputed) 5 cirrhosis of liver http://www.ebi.ac.uk/efo/EFO_0001422 GCST011586 Genome-wide genotyping array 440073 2021-04-27 32961455 Song W 2020-09-15 Drug Alcohol Depend www.ncbi.nlm.nih.gov/pubmed/32961455 Genome-wide association analysis of opioid use disorder: A novel approach using clinical data. Opioid use disorder vs exposed controls 1,039 European ancestry cases, 10,744 European ancestry controls NA Illumina [5508534] (imputed) 2 opioid use disorder http://www.ebi.ac.uk/efo/EFO_0010702 GCST011562 Genome-wide genotyping array 11783 2021-04-27 32961455 Song W 2020-09-15 Drug Alcohol Depend www.ncbi.nlm.nih.gov/pubmed/32961455 Genome-wide association analysis of opioid use disorder: A novel approach using clinical data. Opioid use disorder 1,039 European ancestry cases, 20,271 European ancestry controls NA Illumina [5508534] (imputed) 1 opioid use disorder http://www.ebi.ac.uk/efo/EFO_0010702 GCST011563 Genome-wide genotyping array 21310 2021-05-04 32965087 Zamanpoor M 2020-09-23 Mol Genet Genomic Med www.ncbi.nlm.nih.gov/pubmed/32965087 The genetic basis for the inverse relationship between rheumatoid arthritis and schizophrenia. Rheumatoid arthritis or schizophrenia 29,880 European and Asian ancestry rheumatoid arthritis cases, 7,699 Chinese ancestry schizophrenia cases, 35,476 schizophrenia cases, 73,758 European and Asian ancestry controls, 18,327 Chinese ancestry controls, 46,839 controls NA NR [1483435] 0 rheumatoid arthritis, schizophrenia http://www.ebi.ac.uk/efo/EFO_0000685, http://www.ebi.ac.uk/efo/EFO_0000692 GCST011619 Genome-wide genotyping array 211979 2020-10-30 31566214 Kulminski AM 2019-09-30 J Gerontol A Biol Sci Med Sci www.ncbi.nlm.nih.gov/pubmed/31566214 Quantitative and qualitative role of antagonistic heterogeneity in genetics of blood lipids. High density lipoprotein cholesterol levels 29,902 European ancestry individuals NA Affymetrix, Illumina [up to 2500000] (imputed) 18 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST90010361 Genome-wide genotyping array 29902 2020-10-30 31566214 Kulminski AM 2019-09-30 J Gerontol A Biol Sci Med Sci www.ncbi.nlm.nih.gov/pubmed/31566214 Quantitative and qualitative role of antagonistic heterogeneity in genetics of blood lipids. Triglyceride levels 29,902 European ancestry individuals NA Affymetrix, Illumina [up to 2500000] (imputed) 13 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST90010362 Genome-wide genotyping array 29902 2020-10-30 31566214 Kulminski AM 2019-09-30 J Gerontol A Biol Sci Med Sci www.ncbi.nlm.nih.gov/pubmed/31566214 Quantitative and qualitative role of antagonistic heterogeneity in genetics of blood lipids. Total cholesterol levels 29,902 European ancestry individuals NA Affymetrix, Illumina [up to 2500000] (imputed) 24 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST90010363 Genome-wide genotyping array 29902 2020-10-30 31566214 Kulminski AM 2019-09-30 J Gerontol A Biol Sci Med Sci www.ncbi.nlm.nih.gov/pubmed/31566214 Quantitative and qualitative role of antagonistic heterogeneity in genetics of blood lipids. Low density lipoprotein cholesterol levels 29,902 European ancestry individuals NA Affymetrix, Illumina [up to 2500000] (imputed) 14 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST90010364 Genome-wide genotyping array 29902 2021-06-04 33203692 Labadie JD 2020-11-17 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/33203692 Genetic predictors of severe skin toxicity in stage III colon cancer patients treated with cetuximab: NCCTG N0147 (Alliance). Severe skin toxicity response to cetuximab in stage 3 colon cancer 216 European ancestry cases, 12 African ancestry cases, 9 Asian ancestry cases, 3 Oceanian ancestry cases, 3 cases, 819 European ancestry controls, 74 African ancestry controls, 51 Asian ancestry controls, 4 American Indian ancestry controls, 3 Oceanian ancestry controls, 15 controls NA Illumina [10574903] (imputed) 2 skin disease, colon carcinoma, response to cetuximab http://www.ebi.ac.uk/efo/EFO_0000701, http://www.ebi.ac.uk/efo/EFO_1001950, http://www.ebi.ac.uk/efo/EFO_0007682 GCST011795 Genome-wide genotyping array 1209 2021-04-16 33514863 Nishiguchi KM 2021-01-29 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33514863 A hypomorphic variant in EYS detected by genome-wide association study contributes toward retinitis pigmentosa. Retinitis pigmentosa 432 Japanese ancestry cases, 603 Japanese ancestry controls NA Illumina [10673864] (imputed) 8 Retinitis pigmentosa http://www.orpha.net/ORDO/Orphanet_791 GCST90011892 Genome-wide genotyping array 1035 2021-04-16 33514863 Nishiguchi KM 2021-01-29 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33514863 A hypomorphic variant in EYS detected by genome-wide association study contributes toward retinitis pigmentosa. Retinitis pigmentosa 208 Japanese ancestry cases, 287 Japanese ancestry controls NA Illumina [10383808] (imputed) 2 Retinitis pigmentosa http://www.orpha.net/ORDO/Orphanet_791 GCST90011893 Genome-wide genotyping array 495 2021-04-16 33514863 Nishiguchi KM 2021-01-29 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33514863 A hypomorphic variant in EYS detected by genome-wide association study contributes toward retinitis pigmentosa. Retinitis pigmentosa 640 Japanese ancestry cases, 890 Japanese ancestry controls NA Illumina [11309118] (imputed) 13 Retinitis pigmentosa http://www.orpha.net/ORDO/Orphanet_791 GCST90011894 Genome-wide genotyping array 1530 2021-08-27 33751636 Wei Y 2021-03-09 Biom J www.ncbi.nlm.nih.gov/pubmed/33751636 Confident identification of subgroups from SNP testing in RCTs with binary outcomes. Response to antioxidants and zinc in age-related macular degeneration (disease progression) 450 European ancestry AREDS formula treated cases, 677 European ancestry placebo treated cases NA Illumina [3895495] 2 response to drug, disease progression measurement http://purl.obolibrary.org/obo/GO_0042493, http://www.ebi.ac.uk/efo/EFO_0008336 GCST012255 Genome-wide genotyping array 1127 2021-04-23 33830302 Inshaw JRJ 2021-04-08 Diabetologia www.ncbi.nlm.nih.gov/pubmed/33830302 Analysis of overlapping genetic association in type 1 and type 2 diabetes. Type 1 diabetes 7,467 European ancestry cases, 10,218 European ancestry controls NA Affymetrix, Illumina [7769284] (imputed) 8 type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001359 GCST90000529 Genome-wide genotyping array 17685 2021-04-23 33830302 Inshaw JRJ 2021-04-08 Diabetologia www.ncbi.nlm.nih.gov/pubmed/33830302 Analysis of overlapping genetic association in type 1 and type 2 diabetes. Type 1 or type 2 diabetes (pleiotropy) 81,591 European ancestry cases, 834,224 European ancestry controls NA Affymetrix, Illumina [at least 7769284] (imputed) 0 type I diabetes mellitus, type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001359, http://www.ebi.ac.uk/efo/EFO_0001360 GCST011539 Genome-wide genotyping array 915815 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Chronic sinusitis 3,014 cases, 481,584 controls NA NR [9886868] 0 sinusitis http://www.ebi.ac.uk/efo/EFO_0007486 GCST90038673 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Connective tissue disorder 3,206 cases, 481,392 controls NA NR [9886868] 0 connective tissue disease http://www.ebi.ac.uk/efo/EFO_1001986 GCST90038660 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Deep venous thrombosis 9,529 cases, 475,069 controls NA NR [9886868] 0 deep vein thrombosis http://www.ebi.ac.uk/efo/EFO_0003907 GCST90038615 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Depression 27,568 cases, 457,030 controls NA NR [9886868] 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90038650 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Dermatologic disease 20,101 cases, 464,497 controls NA NR [9886868] 0 skin disease http://www.ebi.ac.uk/efo/EFO_0000701 GCST90038679 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Arthritis (not osteoarthritis) 3,777 cases, 480,821 controls NA NR [9886868] 0 arthritis http://www.ebi.ac.uk/efo/EFO_0005856 GCST90038699 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Asthma 56,087 cases, 428,511 controls NA NR [9886868] 0 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST90038616 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Disc problem 9,190 cases, 475,408 controls NA NR [9886868] 0 vertebral disease http://purl.obolibrary.org/obo/MONDO_0045002 GCST90038697 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Diverticular disease 5,218 cases, 479,380 controls NA NR [9886868] 0 diverticular disease http://www.ebi.ac.uk/efo/EFO_0009959 GCST90038682 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Drug allergy or anaphylactic reaction 4,133 cases, 480,465 controls NA NR [9886868] 0 drug allergy http://www.ebi.ac.uk/efo/EFO_0009482 GCST90038663 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Ear disorder 7,134 cases, 477,464 controls NA NR [9886868] 0 disease of ear http://purl.obolibrary.org/obo/MONDO_0021205 GCST90038672 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Ear-nose-throat disorder 17,317 cases, 467,281 controls NA NR [9886868] 0 otorhinolaryngologic disease http://purl.obolibrary.org/obo/MONDO_0024623 GCST90038669 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Eczema or dermatitis 12,176 cases, 472,422 controls NA NR [9886868] 0 Eczema, dermatitis http://purl.obolibrary.org/obo/HP_0000964, http://purl.obolibrary.org/obo/MONDO_0002406 GCST90038680 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Emphysema or chronic bronchitis 10,174 cases, 474,424 controls NA NR [9886868] 0 emphysema, chronic bronchitis http://www.ebi.ac.uk/efo/EFO_0000464, http://www.ebi.ac.uk/efo/EFO_0006505 GCST90038617 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Epilepsy 3,900 cases, 480,698 controls NA NR [9886868] 0 epilepsy http://www.ebi.ac.uk/efo/EFO_0000474 GCST90038645 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Esophageal disorder 31,526 cases, 453,072 controls NA NR [9886868] 0 esophageal disease http://www.ebi.ac.uk/efo/EFO_0009544 GCST90038619 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Cerebrovascular disease 8,915 cases, 475,683 controls NA NR [9886868] 0 cerebrovascular disorder http://www.ebi.ac.uk/efo/EFO_0003763 GCST90038606 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Cervical spondylosis 3,352 cases, 481,246 controls NA NR [9886868] 0 cervical spondylosis http://www.ebi.ac.uk/efo/EFO_0009610 GCST90038693 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Cholelithiasis or gall stones 7,895 cases, 476,703 controls NA NR [9886868] 0 cholelithiasis, gallstones http://www.ebi.ac.uk/efo/EFO_0004799, http://www.ebi.ac.uk/efo/EFO_0004210 GCST90038629 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Chronic fatigue syndrome 2,092 cases, 482,506 controls NA NR [9886868] 0 chronic fatigue syndrome http://www.ebi.ac.uk/efo/EFO_0004540 GCST90038694 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Chronic or degenerative neurological problem 2,960 cases, 481,638 controls NA NR [9886868] 0 nervous system disease http://www.ebi.ac.uk/efo/EFO_0000618 GCST90038644 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Fracture of upper limb or shoulder 4,335 cases, 480,263 controls NA NR [9886868] 0 bone fracture http://www.ebi.ac.uk/efo/EFO_0003931 GCST90038704 Genome-wide genotyping array 484598 2021-11-12 33959723 Donertas HM 2021-04-08 Nat Aging www.ncbi.nlm.nih.gov/pubmed/33959723 Common genetic associations between age-related diseases. Gallbladder disease 8,587 cases, 476,011 controls NA NR [9886868] 0 gallbladder disease http://www.ebi.ac.uk/efo/EFO_0003832 GCST90038628 Genome-wide genotyping array 484598 2021-10-13 34020725 Reddy JS 2021-05-21 Acta Neuropathol Commun www.ncbi.nlm.nih.gov/pubmed/34020725 Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer's disease. Cerebral amyloid angiopathy in APOEe4 carrier Alzheimer’s disease 534 European ancestry individuals NA Illumina [1679420] (imputed) 1 cerebral amyloid angiopathy http://www.ebi.ac.uk/efo/EFO_0006790 GCST012482 Genome-wide genotyping array 534 2021-10-13 34020725 Reddy JS 2021-05-21 Acta Neuropathol Commun www.ncbi.nlm.nih.gov/pubmed/34020725 Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer's disease. Cerebral amyloid angiopathy in APOEe4 non-carrier Alzheimer’s disease 287 European ancestry individuals NA Illumina [1679420] (imputed) 5 cerebral amyloid angiopathy http://www.ebi.ac.uk/efo/EFO_0006790 GCST012483 Genome-wide genotyping array 287 2021-10-13 34020725 Reddy JS 2021-05-21 Acta Neuropathol Commun www.ncbi.nlm.nih.gov/pubmed/34020725 Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer's disease. Cerebral amyloid angiopathy x sex interaction in Alzheimer’s disease 370 European ancestry men, 451 European ancestry women NA Illumina [1679420] (imputed) 15 sex interaction measurement, cerebral amyloid angiopathy http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0006790 GCST012485 Genome-wide genotyping array 821 2021-10-13 34020725 Reddy JS 2021-05-21 Acta Neuropathol Commun www.ncbi.nlm.nih.gov/pubmed/34020725 Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer's disease. Cerebral amyloid angiopathy x APOEe4 status interaction in Alzheimer’s disease 534 European ancestry APOEe4 carriers, 287 European ancestry APOEe4 non-carriers NA Illumina [1679420] (imputed) 25 APOE carrier status, cerebral amyloid angiopathy http://www.ebi.ac.uk/efo/EFO_0007659, http://www.ebi.ac.uk/efo/EFO_0006790 GCST012484 Genome-wide genotyping array 829 2021-10-13 34020725 Reddy JS 2021-05-21 Acta Neuropathol Commun www.ncbi.nlm.nih.gov/pubmed/34020725 Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer's disease. Cerebral amyloid angiopathy in Alzheimer’s disease 821 European ancestry individuals NA Illumina [1679420] (imputed) 16 cerebral amyloid angiopathy http://www.ebi.ac.uk/efo/EFO_0006790 GCST012481 Genome-wide genotyping array 821 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 1) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 2 facial morphology measurement http://www.ebi.ac.uk/efo/EFO_0007841 GCST90044778 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 2) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 0 facial morphology measurement http://www.ebi.ac.uk/efo/EFO_0007841 GCST90044779 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 3) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 1 facial morphology measurement http://www.ebi.ac.uk/efo/EFO_0007841 GCST90044780 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 4) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 1 lower face morphology measurement http://www.ebi.ac.uk/efo/EFO_0010948 GCST90044781 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 5) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 0 upper face morphology measurement http://www.ebi.ac.uk/efo/EFO_0010949 GCST90044782 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 6) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90044783 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 7) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 0 lip morphology measurement, eye morphology measurement http://www.ebi.ac.uk/efo/EFO_0007845, http://www.ebi.ac.uk/efo/EFO_0007858 GCST90044784 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 8) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 0 chin morphology measurement http://www.ebi.ac.uk/efo/EFO_0007842 GCST90044785 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 9) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 0 lower face morphology measurement http://www.ebi.ac.uk/efo/EFO_0010948 GCST90044786 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 10) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 0 upper face morphology measurement http://www.ebi.ac.uk/efo/EFO_0010949 GCST90044787 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 11) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 1 upper face morphology measurement http://www.ebi.ac.uk/efo/EFO_0010949 GCST90044788 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 12) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90044789 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 13) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90044790 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 14) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 1 eye morphology measurement http://www.ebi.ac.uk/efo/EFO_0007858 GCST90044791 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 15) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 0 lip morphology measurement http://www.ebi.ac.uk/efo/EFO_0007845 GCST90044792 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 16) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 0 chin morphology measurement http://www.ebi.ac.uk/efo/EFO_0007842 GCST90044793 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 17) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 0 chin morphology measurement http://www.ebi.ac.uk/efo/EFO_0007842 GCST90044794 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 18) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 1 lower face morphology measurement http://www.ebi.ac.uk/efo/EFO_0010948 GCST90044795 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 19) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 0 lower face morphology measurement http://www.ebi.ac.uk/efo/EFO_0010948 GCST90044796 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 20) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 0 forehead morphology measurement http://www.ebi.ac.uk/efo/EFO_0007844 GCST90044797 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 21) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 1 upper face morphology measurement http://www.ebi.ac.uk/efo/EFO_0010949 GCST90044798 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 22) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 0 upper face morphology measurement http://www.ebi.ac.uk/efo/EFO_0010949 GCST90044799 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 23) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 0 upper face morphology measurement http://www.ebi.ac.uk/efo/EFO_0010949 GCST90044800 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 24) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90044801 Genome-wide genotyping array 2595 2021-11-15 34411106 Liu C 2021-08-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34411106 Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. Facial morphology (segment 25) 2,595 Tanzanian ancestry individuals NA Illumina [NR] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90044802 Genome-wide genotyping array 2595 2021-10-19 33992511 Chang X 2021-04-07 Nutr Metab Cardiovasc Dis www.ncbi.nlm.nih.gov/pubmed/33992511 The association of genetically determined serum glycine with cardiovascular risk in East Asians. Glycine levels 1,324 Chinese ancestry individuals NA NR [NR] (imputed) 2 glycine measurement http://www.ebi.ac.uk/efo/EFO_0009767 GCST90044914 Genome-wide genotyping array 1324 2021-10-07 34117260 Chen G 2021-06-11 NPJ Genom Med www.ncbi.nlm.nih.gov/pubmed/34117260 A UGT1A1 variant is associated with serum total bilirubin levels, which are causal for hypertension in African-ancestry individuals. Total bilirubin levels 1,127 West African individuals NA Affymetrix, Illumina [NR] (imputed) 2 bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004570 GCST012461 Genome-wide genotyping array 1127 2021-10-22 34445011 Park S 2021-08-19 Nutrients www.ncbi.nlm.nih.gov/pubmed/34445011 Association between Polygenetic Risk Scores of Low Immunity and Interactions between These Scores and Moderate Fat Intake in a Large Cohort. Low white blood cell count 4,176 Korean ancestry low WBC count cases, 36,551 Korean ancestry high WBC count controls 207 Korean ancestry low WBC count cases, 5,286 Korean ancestry high WBC count controls Affymetrix [NR] 0 leukocyte count http://www.ebi.ac.uk/efo/EFO_0004308 GCST90029071 Genome-wide genotyping array 40727 2021-11-08 33766948 Zhu Z 2021-03-25 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/33766948 A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic etiology with obesity. Lung function (FEV1) 100,285 Chinese ancestry individuals NA Affymetrix [NR] (imputed) 27 forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0004314 GCST90054783 Genome-wide genotyping array 100285 2021-11-08 33766948 Zhu Z 2021-03-25 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/33766948 A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic etiology with obesity. Lung function (FVC) 100,285 Chinese ancestry individuals NA Affymetrix [NR] (imputed) 8 vital capacity http://www.ebi.ac.uk/efo/EFO_0004312 GCST90054784 Genome-wide genotyping array 100285 2021-11-08 33766948 Zhu Z 2021-03-25 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/33766948 A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic etiology with obesity. Lung function (FEV1/FVC) 100,285 Chinese ancestry individuals NA Affymetrix [NR] (imputed) 6 FEV/FEC ratio http://www.ebi.ac.uk/efo/EFO_0004713 GCST90054785 Genome-wide genotyping array 100285 2021-11-08 33766948 Zhu Z 2021-03-25 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/33766948 A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic etiology with obesity. Lung function (FEV1) and body mass index up to 100,285 Chinese ancestry individuals up to 457,756 European ancestry individuals Affymetrix [NR] (imputed) 7 forced expiratory volume, body mass index http://www.ebi.ac.uk/efo/EFO_0004314, http://www.ebi.ac.uk/efo/EFO_0004340 GCST90054786 Genome-wide genotyping array 100285 2021-11-08 33766948 Zhu Z 2021-03-25 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/33766948 A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic etiology with obesity. Lung function (FEV1) and waist to hip ratio adjusted for BMI up to 100,285 Chinese ancestry individuals up to 457,756 European ancestry individuals Affymetrix [NR] (imputed) 5 BMI-adjusted waist-hip ratio, forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0004314 GCST90054787 Genome-wide genotyping array 100285 2021-11-08 33766948 Zhu Z 2021-03-25 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/33766948 A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic etiology with obesity. Lung function (FEV1) and waist circumference adjusted for BMI up to 100,285 Chinese ancestry individuals up to 457,756 European ancestry individuals Affymetrix [NR] (imputed) 7 BMI-adjusted waist circumference, forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0004314 GCST90054788 Genome-wide genotyping array 100285 2021-11-08 33766948 Zhu Z 2021-03-25 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/33766948 A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic etiology with obesity. Lung function (FVC) and body mass index up to 100,285 Chinese ancestry individuals up to 457,756 European ancestry individuals Affymetrix [NR] (imputed) 4 body mass index, vital capacity http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004312 GCST90054789 Genome-wide genotyping array 100285 2021-11-08 33766948 Zhu Z 2021-03-25 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/33766948 A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic etiology with obesity. Lung function (FVC) and waist to hip ratio adjusted for BMI up to 100,285 Chinese ancestry individuals up to 457,756 European ancestry individuals Affymetrix [NR] (imputed) 1 BMI-adjusted waist-hip ratio, vital capacity http://www.ebi.ac.uk/efo/EFO_0007788, http://www.ebi.ac.uk/efo/EFO_0004312 GCST90054790 Genome-wide genotyping array 100285 2021-11-08 33766948 Zhu Z 2021-03-25 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/33766948 A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic etiology with obesity. Lung function (FVC) and waist circumference adjusted for BMI up to 100,285 Chinese ancestry individuals up to 457,756 European ancestry individuals Affymetrix [NR] (imputed) 1 BMI-adjusted waist circumference, vital capacity http://www.ebi.ac.uk/efo/EFO_0007789, http://www.ebi.ac.uk/efo/EFO_0004312 GCST90054791 Genome-wide genotyping array 100285 2021-11-08 33766948 Zhu Z 2021-03-25 Eur Respir J www.ncbi.nlm.nih.gov/pubmed/33766948 A large-scale genome-wide association analysis of lung function in the Chinese population identifies novel loci and highlights shared genetic etiology with obesity. Lung function (FEV1/FVC) and body mass index up to 100,285 Chinese ancestry individuals up to 457,756 European ancestry individuals Affymetrix [NR] (imputed) 0 body mass index, FEV/FEC ratio http://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004713 GCST90054792 Genome-wide genotyping array 100285 2021-10-20 34309201 Yu Y 2021-07-26 Mol Oncol www.ncbi.nlm.nih.gov/pubmed/34309201 A comprehensive analysis of SNPs and CNVs identifies novel markers associated with disease outcomes in colorectal cancer. Disease free survival in colorectal cancer 505 European ancestry individuals NA Illumina [4711309] (imputed) 15 disease free survival http://www.ebi.ac.uk/efo/EFO_0000409 GCST90053837 Genome-wide genotyping array 505 2021-10-20 34309201 Yu Y 2021-07-26 Mol Oncol www.ncbi.nlm.nih.gov/pubmed/34309201 A comprehensive analysis of SNPs and CNVs identifies novel markers associated with disease outcomes in colorectal cancer. Recurrence-free survival in colorectal cancer 505 European ancestry individuals NA Illumina [4711309] (imputed) 0 event free survival time http://www.ebi.ac.uk/efo/EFO_0000482 GCST90053838 Genome-wide genotyping array 505 2021-10-25 34220922 Wang J 2021-06-17 Front Genet www.ncbi.nlm.nih.gov/pubmed/34220922 Genome-Wide Association Analyses Identify Variants in IRF4 Associated With Acute Myeloid Leukemia and Myelodysplastic Syndrome Susceptibility. Therapy-related myelodysplastic syndrome 96 European ancestry cases, 2,814 European ancestry controls NA Illumina [9000000] (imputed) 1 myelodysplastic syndrome http://www.ebi.ac.uk/efo/EFO_0000198 GCST90020097 Genome-wide genotyping array 2910 2021-10-25 34220922 Wang J 2021-06-17 Front Genet www.ncbi.nlm.nih.gov/pubmed/34220922 Genome-Wide Association Analyses Identify Variants in IRF4 Associated With Acute Myeloid Leukemia and Myelodysplastic Syndrome Susceptibility. De novo myelodysplastic syndrome 444 European ancestry cases, 2,814 European ancestry controls NA Illumina [9000000] (imputed) 0 myelodysplastic syndrome http://www.ebi.ac.uk/efo/EFO_0000198 GCST90020098 Genome-wide genotyping array 3258 2021-10-25 34220922 Wang J 2021-06-17 Front Genet www.ncbi.nlm.nih.gov/pubmed/34220922 Genome-Wide Association Analyses Identify Variants in IRF4 Associated With Acute Myeloid Leukemia and Myelodysplastic Syndrome Susceptibility. Therapy-related acute myeloid leukemia 146 European ancestry cases, 2,814 European ancestry controls NA Illumina [9000000] (imputed) 0 acute myeloid leukemia http://www.ebi.ac.uk/efo/EFO_0000222 GCST90054800 Genome-wide genotyping array 2960 2021-10-25 34220922 Wang J 2021-06-17 Front Genet www.ncbi.nlm.nih.gov/pubmed/34220922 Genome-Wide Association Analyses Identify Variants in IRF4 Associated With Acute Myeloid Leukemia and Myelodysplastic Syndrome Susceptibility. De novo acute myeloid leukemia (normal cytogenetics) 543 European ancestry cases, 2,814 European ancestry controls NA Illumina [9000000] (imputed) 0 acute myeloid leukemia http://www.ebi.ac.uk/efo/EFO_0000222 GCST90054801 Genome-wide genotyping array 3357 2021-10-25 34220922 Wang J 2021-06-17 Front Genet www.ncbi.nlm.nih.gov/pubmed/34220922 Genome-Wide Association Analyses Identify Variants in IRF4 Associated With Acute Myeloid Leukemia and Myelodysplastic Syndrome Susceptibility. De novo acute myeloid leukemia (abnormal cytogenetics) 836 European ancestry cases, 2,814 European ancestry controls NA Illumina [9000000] (imputed) 0 acute myeloid leukemia http://www.ebi.ac.uk/efo/EFO_0000222 GCST90054802 Genome-wide genotyping array 3650 2021-10-25 34220922 Wang J 2021-06-17 Front Genet www.ncbi.nlm.nih.gov/pubmed/34220922 Genome-Wide Association Analyses Identify Variants in IRF4 Associated With Acute Myeloid Leukemia and Myelodysplastic Syndrome Susceptibility. Acute myeloid leukemia or myelodysplastic syndrome (pleiotropy) 1,769 European ancestry acute myeloid leukemia cases, 540 myelodysplastic syndrome cases, 2,814 European ancestry controls NA Illumina [9000000] (imputed) 1 acute myeloid leukemia, myelodysplastic syndrome http://www.ebi.ac.uk/efo/EFO_0000222, http://www.ebi.ac.uk/efo/EFO_0000198 GCST90020096 Genome-wide genotyping array 5123 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis of the hip or knee up to 400,604 European, Japanese ancestry female cases, up to 490,345 European, Japanese ancestry female controls NA Affymetrix, Illumina [NR] (imputed) 0 osteoarthritis, hip, osteoarthritis, knee http://www.ebi.ac.uk/efo/EFO_1000786, http://www.ebi.ac.uk/efo/EFO_0004616 GCST90061021 Genome-wide genotyping array 890949 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis (hip) up to 36,445 European ancestry female cases, up to 316,943 European ancestry female controls NA Affymetrix, Illumina [NR] (imputed) 0 osteoarthritis, hip http://www.ebi.ac.uk/efo/EFO_1000786 GCST90061022 Genome-wide genotyping array 353388 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Knee osteoarthritis up to 333,557 European, Japanese ancestry female cases, up to 396,054 European, Japanese ancestry female controls NA Affymetrix, Illumina [NR] (imputed) 0 osteoarthritis, knee http://www.ebi.ac.uk/efo/EFO_0004616 GCST90061023 Genome-wide genotyping array 729611 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis (with total hip replacement) up to 23,021 European, East Asian ancestry female cases, up to 296,016 European, East Asian ancestry female controls NA Affymetrix, Illumina [NR] (imputed) 2 total hip arthroplasty, osteoarthritis http://www.ebi.ac.uk/efo/EFO_0009806, http://www.ebi.ac.uk/efo/EFO_0002506 GCST90034531 Genome-wide genotyping array 319037 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis (with total knee replacement) up to 18,200 European ancestry female cases, up to 233,841 European ancestry female controls NA Affymetrix, Illumina [NR] (imputed) 0 osteoarthritis, knee, total joint arthroplasty http://www.ebi.ac.uk/efo/EFO_0004616, http://www.ebi.ac.uk/efo/EFO_0010726 GCST90061024 Genome-wide genotyping array 252041 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis of the hip or knee (with total joint replacement) up to 40,887 European ancestry female cases, up to 327,689 European ancestry female controls NA Affymetrix, Illumina [NR] (imputed) 0 osteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty http://www.ebi.ac.uk/efo/EFO_1000786, http://www.ebi.ac.uk/efo/EFO_0004616, http://www.ebi.ac.uk/efo/EFO_0010726 GCST90061025 Genome-wide genotyping array 368576 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis of the hand up to 20,901 European ancestry female cases, up to 282,881 European ancestry female controls NA Affymetrix, Illumina [NR] (imputed) 0 osteoarthritis, hand http://www.ebi.ac.uk/efo/EFO_1000789 GCST90061026 Genome-wide genotyping array 303782 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Finger osteoarthritis up to 10,804 European ancestry female cases, up to 255,814 European ancestry female controls NA Affymetrix, Illumina [NR] (imputed) 0 osteoarthritis, hand http://www.ebi.ac.uk/efo/EFO_1000789 GCST90061027 Genome-wide genotyping array 266618 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Thumb osteoarthritis up to 10,536 European ancestry female cases, up to 236,919 European ancestry female controls NA Affymetrix, Illumina [NR] (imputed) 0 osteoarthritis, hand http://www.ebi.ac.uk/efo/EFO_1000789 GCST90061028 Genome-wide genotyping array 247455 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Spine osteoarthritis up to 305,578 East Asian ancestry female cases, up to 333,950 East Asian ancestry female controls NA Affymetrix, Illumina [NR] (imputed) 0 osteoarthritis, spine http://www.ebi.ac.uk/efo/EFO_1000787 GCST90061029 Genome-wide genotyping array 639528 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis up to 56,462 European, East Asian ancestry male cases, up to 153,808 European ancestry European, East Asian ancestry male controls NA Affymetrix, Illumina [NR] (imputed) 0 osteoarthritis http://www.ebi.ac.uk/efo/EFO_0002506 GCST90061030 Genome-wide genotyping array 210270 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis of the hip or knee up to 400,604 Japanese, European ancestry male cases, up to 490,345 Japanese, European ancestry male controls NA Affymetrix, Illumina [NR] (imputed) 0 osteoarthritis, hip, osteoarthritis, knee http://www.ebi.ac.uk/efo/EFO_1000786, http://www.ebi.ac.uk/efo/EFO_0004616 GCST90061031 Genome-wide genotyping array 890949 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis (hip) up to 36,445 European ancestry male cases, up to 316,943 European ancestry male controls NA Affymetrix, Illumina [NR] (imputed) 0 osteoarthritis, hip http://www.ebi.ac.uk/efo/EFO_1000786 GCST90061032 Genome-wide genotyping array 353388 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Knee osteoarthritis up to 333,557 European, Japanese ancestry male cases, up to 396,054 European, Japanese ancestry male controls NA Affymetrix, Illumina [NR] (imputed) 0 osteoarthritis, knee http://www.ebi.ac.uk/efo/EFO_0004616 GCST90061033 Genome-wide genotyping array 729611 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis (with total hip replacement) 23,021 European, East Asian ancestry male cases, 296,016 European, East Asian ancestry male controls NA Affymetrix, Illumina [NR] (imputed) 0 total hip arthroplasty, osteoarthritis http://www.ebi.ac.uk/efo/EFO_0009806, http://www.ebi.ac.uk/efo/EFO_0002506 GCST90061034 Genome-wide genotyping array 319037 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis (with total knee replacement) up to 18,200 European ancestry male cases, up to 233,841 European ancestry male controls NA Affymetrix, Illumina [NR] (imputed) 0 osteoarthritis, knee, total joint arthroplasty http://www.ebi.ac.uk/efo/EFO_0004616, http://www.ebi.ac.uk/efo/EFO_0010726 GCST90061035 Genome-wide genotyping array 252041 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis of the hip or knee (with total joint replacement) up to 40,887 European ancestry male cases, up to 327,689 European ancestry male controls NA Affymetrix, Illumina [NR] (imputed) 0 osteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty http://www.ebi.ac.uk/efo/EFO_1000786, http://www.ebi.ac.uk/efo/EFO_0004616, http://www.ebi.ac.uk/efo/EFO_0010726 GCST90061036 Genome-wide genotyping array 368576 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis of the hand up to 20,901 European ancestry male cases, up to 282,881 European ancestry male controls NA Affymetrix, Illumina [NR] (imputed) 0 osteoarthritis, hand http://www.ebi.ac.uk/efo/EFO_1000789 GCST90061037 Genome-wide genotyping array 303782 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Finger osteoarthritis up to 10,804 European ancestry male cases, up to 255,814 European ancestry male controls NA Affymetrix, Illumina [NR] (imputed) 0 osteoarthritis, hand http://www.ebi.ac.uk/efo/EFO_1000789 GCST90061038 Genome-wide genotyping array 266618 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Thumb osteoarthritis up to 10,536 European ancestry male cases, up to 236,919 European ancestry male controls NA Affymetrix, Illumina [NR] (imputed) 0 osteoarthritis, hand http://www.ebi.ac.uk/efo/EFO_1000789 GCST90061039 Genome-wide genotyping array 247455 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Spine osteoarthritis up to 305,578 European, East Asian ancestry male cases, up to 333,950 European, East Asian ancestry male controls NA Affymetrix, Illumina [NR] (imputed) 0 osteoarthritis, spine http://www.ebi.ac.uk/efo/EFO_1000787 GCST90061040 Genome-wide genotyping array 639528 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis of the hip or knee 88,842 European ancestry cases, 397,208 European ancestry controls, 899 Japanese ancestry cases, 3,396 Japanese ancestry controls NA Affymetrix, Illumina [NR] (imputed) 16 osteoarthritis, hip, osteoarthritis, knee http://www.ebi.ac.uk/efo/EFO_1000786, http://www.ebi.ac.uk/efo/EFO_0004616 GCST90034521 Genome-wide genotyping array 490345 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis 175,803 European ancestry cases, 644,862 European ancestry controls, 1,265 Japanese ancestry cases, 449 Southern Chinese ancestry cases, 3,330 Japanese ancestry controls, 981 Southern Chinese ancestry controls NA Affymetrix, Illumina [NR] (imputed) 11 osteoarthritis http://www.ebi.ac.uk/efo/EFO_0002506 GCST90034520 Genome-wide genotyping array 826690 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis (hip) 36,445 European ancestry cases, 316,943 European ancestry controls NA Affymetrix, Illumina [NR] (imputed) 11 osteoarthritis, hip http://www.ebi.ac.uk/efo/EFO_1000786 GCST90034522 Genome-wide genotyping array 353388 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Knee osteoarthritis 61,588 European ancestry cases, 330,161 European ancestry controls, 899 Japanese ancestry cases, 3,396 Japanese ancestry controls NA Affymetrix, Illumina [NR] (imputed) 10 osteoarthritis, knee http://www.ebi.ac.uk/efo/EFO_0004616 GCST90034523 Genome-wide genotyping array 396044 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis (with total hip replacement) 23,021 European ancestry cases, 296,016 European ancestry controls NA Affymetrix, Illumina [NR] (imputed) 27 total hip arthroplasty, osteoarthritis http://www.ebi.ac.uk/efo/EFO_0009806, http://www.ebi.ac.uk/efo/EFO_0002506 GCST90034524 Genome-wide genotyping array 319037 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis (with total knee replacement) 18,200 European ancestry cases, 233,841 European ancestry controls NA Affymetrix, Illumina [NR] (imputed) 3 osteoarthritis, knee, total joint arthroplasty http://www.ebi.ac.uk/efo/EFO_0004616, http://www.ebi.ac.uk/efo/EFO_0010726 GCST90034525 Genome-wide genotyping array 252041 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis of the hip or knee (with total joint replacement) 40,887 European ancestry cases, 327,689 European ancestry controls NA Affymetrix, Illumina [NR] (imputed) 13 osteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty http://www.ebi.ac.uk/efo/EFO_1000786, http://www.ebi.ac.uk/efo/EFO_0004616, http://www.ebi.ac.uk/efo/EFO_0010726 GCST90034526 Genome-wide genotyping array 368576 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis of the hand 20,901 European ancestry cases, 282,881 European ancestry controls NA Affymetrix, Illumina [NR] (imputed) 5 osteoarthritis, hand http://www.ebi.ac.uk/efo/EFO_1000789 GCST90034527 Genome-wide genotyping array 303782 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Finger osteoarthritis 10,804 European ancestry cases, 255,814 European ancestry controls NA Affymetrix, Illumina [NR] (imputed) 3 osteoarthritis, hand http://www.ebi.ac.uk/efo/EFO_1000789 GCST90034528 Genome-wide genotyping array 266618 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Thumb osteoarthritis 10,536 European ancestry cases, 236,919 European ancestry controls NA Affymetrix, Illumina [NR] (imputed) 1 osteoarthritis, hand http://www.ebi.ac.uk/efo/EFO_1000789 GCST90034529 Genome-wide genotyping array 247455 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Spine osteoarthritis 27,557 European ancestry cases, 301,266 European ancestry controls, 366 Japanese ancestry cases, 3331 Japanese ancestry controls, 449 Southern Chinese ancestry cases, 981 Southern Chinese ancestry controls NA Affymetrix, Illumina [NR] (imputed) 0 osteoarthritis, spine http://www.ebi.ac.uk/efo/EFO_1000787 GCST90034530 Genome-wide genotyping array 333950 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Early-onset osteoarthritis 6,838 European ancestry cases, 41,449 European ancestry controls NA Affymetrix, Illumina [NR] (imputed) 1 age at onset, osteoarthritis http://www.ebi.ac.uk/efo/EFO_0004847, http://www.ebi.ac.uk/efo/EFO_0002506 GCST90034533 Genome-wide genotyping array 48287 2021-11-01 34450027 Boer CG 2021-08-24 Cell www.ncbi.nlm.nih.gov/pubmed/34450027 Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Osteoarthritis 90,838 European, East Asian ancestry female cases, 192,697 European, East Asian ancestry female controls NA Affymetrix, Illumina [NR] (imputed) 1 osteoarthritis http://www.ebi.ac.uk/efo/EFO_0002506 GCST90034532 Genome-wide genotyping array 283535 2021-11-02 34493870 Wightman DP 2021-09-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34493870 A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease. Late-onset Alzheimer's disease 90,338 cases, 1,036,225 controls NA Illumina [NR] (imputed) 38 late-onset Alzheimers disease http://www.ebi.ac.uk/efo/EFO_1001870 GCST90044699 Genome-wide genotyping array 1126563 2021-10-27 34197731 Li Q 2021-06-23 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/34197731 Whole-exome sequencing reveals common and rare variants in immunologic and neurological genes implicated in achalasia. Idiopathic achalasia 280 Chinese Han ancestry cases, 1,121 Chinese Han ancestry controls NA Illumina [476650] (imputed) 2 Achalasia http://purl.obolibrary.org/obo/HP_0002571 GCST90025934 Genome-wide genotyping array 1401 2021-10-27 34197731 Li Q 2021-06-23 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/34197731 Whole-exome sequencing reveals common and rare variants in immunologic and neurological genes implicated in achalasia. Idiopathic achalasia 100 Chinese Han ancestry cases, 313 Chinese Han ancestry controls 230 Chinese Han ancestry cases, 1,760 Chinese Han ancestry controls Illumina [192329] 2 Achalasia http://purl.obolibrary.org/obo/HP_0002571 GCST90025935 Genome-wide sequencing 413 2021-10-28 33133133 Lee KY 2020-08-28 Front Genet www.ncbi.nlm.nih.gov/pubmed/33133133 Genome-Wide Search for SNP Interactions in GWAS Data: Algorithm, Feasibility, Replication Using Schizophrenia Datasets. Schizophrenia (SNP x SNP interaction) 1,051 European ancestry cases, 1,214 European ancestry controls 829 African American or Afro-Caribbean cases, 874 African American or Afro-Caribbean controls, 1,176 European ancestry, African American or Afro-Caribbean cases, 1,325 European ancestry, African American or Afro-Caribbean controls NR [729454] 0 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST90058030 Genome-wide genotyping array 2265 2021-11-01 34668383 Leskela J 2021-10-20 J Am Heart Assoc www.ncbi.nlm.nih.gov/pubmed/34668383 Genetic Profile of Endotoxemia Reveals an Association With Thromboembolism and Stroke. Serum lipopolysaccharide activity 11,296 European ancestry individuals NA Affymetrix, Illumina [9900000] (imputed) 5 NA NA GCST90032674 Genome-wide genotyping array 11296 2021-11-08 34604815 Polfus LM 2021-03-09 HGG Adv www.ncbi.nlm.nih.gov/pubmed/34604815 Genetic discovery and risk characterization in type 2 diabetes across diverse populations. Type 2 diabetes 29,832 European ancestry cases, 147,369 European ancestry controls, 8,591 African American, African ancestry cases, 16,887 African American African ancestry controls, 3,124 Asian ancestry cases, 4,313 Asian ancestry controls, 1,642 Oceanian ancestry cases, 2,152 Oceanian ancestry controls, 9,913 Hispanic or Latin American cases, 22,958 Hispanic or Latin American controls 109,274 European ancestry cases, 154,346 European ancestry controls, 20,344 African American, African ancestry cases, 97,933 African American, African ancestry controls, 2,237 East Asian ancestry cases, 72,819 East Asian ancestry controls, 1,171 South Asian ancestry cases, 18,874 South Asian ancestry controls, 77,418 Asian ancestry cases, 356,122 Asian ancestry controls, 20,608 Hispanic or Latin American cases, 246,046 Hispanic or Latin American controls Affymetrix, Illumina [NR] (imputed) 0 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST90053824 Genome-wide genotyping array 246781 2021-11-08 34604815 Polfus LM 2021-03-09 HGG Adv www.ncbi.nlm.nih.gov/pubmed/34604815 Genetic discovery and risk characterization in type 2 diabetes across diverse populations. Type 2 diabetes 8,591 African American, African ancestry cases, 16,887 African American, African ancestry controls 20,344 African American, African ancestry cases, 97,933 African American, African ancestry controls Affymetrix, Illumina [NR] (imputed) 1 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST90053830 Genome-wide genotyping array 25478 2021-11-08 34604815 Polfus LM 2021-03-09 HGG Adv www.ncbi.nlm.nih.gov/pubmed/34604815 Genetic discovery and risk characterization in type 2 diabetes across diverse populations. Type 2 diabetes 3,124 Asian ancestry cases, 4,313 Asian ancestry controls 2,237 East Asian ancestry cases, 72,819 East Asian ancestry controls, 1,171 South Asian ancestry cases, 18,874 South Asian ancestry controls, 77,418 Asian ancestry cases, 356,122 Asian ancestry controls Illumina [NR] (imputed) 0 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST90053826 Genome-wide genotyping array 7437 2021-11-08 34604815 Polfus LM 2021-03-09 HGG Adv www.ncbi.nlm.nih.gov/pubmed/34604815 Genetic discovery and risk characterization in type 2 diabetes across diverse populations. Type 2 diabetes 1,642 Native Hawaiian ancestry cases, 2,152 Native Hawaiian ancestry controls NA Illumina [NR] (imputed) 0 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST90053827 Genome-wide genotyping array 3794 2021-11-08 34604815 Polfus LM 2021-03-09 HGG Adv www.ncbi.nlm.nih.gov/pubmed/34604815 Genetic discovery and risk characterization in type 2 diabetes across diverse populations. Type 2 diabetes 29,832 European ancestry cases, 147,369 European ancestry controls 109,274 European ancestry cases, 154,346 European ancestry controls Affymetrix, Illumina [NR] (imputed) 0 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST90053828 Genome-wide genotyping array 177201 2021-11-08 34604815 Polfus LM 2021-03-09 HGG Adv www.ncbi.nlm.nih.gov/pubmed/34604815 Genetic discovery and risk characterization in type 2 diabetes across diverse populations. Type 2 diabetes 9,913 Hispanic or Latin American cases, 22,958 Hispanic or Latin American controls 20,608 Hispanic or Latin American cases, 246,046 Hispanic or Latin American controls Illumina [NR] (imputed) 0 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST90053829 Genome-wide genotyping array 32871 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to idarubicin 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 0 response to topoisomerase inhibitor http://purl.obolibrary.org/obo/GO_0072758 GCST90044856 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to mitoxantrone 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 0 response to topoisomerase inhibitor http://purl.obolibrary.org/obo/GO_0072758 GCST90044857 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to topotecan 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 0 response to topoisomerase inhibitor http://purl.obolibrary.org/obo/GO_0072758 GCST90044858 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to taxane treatment (docetaxel) 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 1 response to docetaxel http://purl.obolibrary.org/obo/GO_1902519 GCST90044859 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to paclitaxel 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 2 response to paclitaxel http://purl.obolibrary.org/obo/GO_1901555 GCST90044860 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to vinblastine 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 1 response to antimicrotubule agent http://www.ebi.ac.uk/efo/EFO_0005260 GCST90044861 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to vincristine sulfate 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 0 response to vincristine http://www.ebi.ac.uk/efo/EFO_0006950 GCST90044862 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to vinorelbine 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 1 response to antimicrotubule agent http://www.ebi.ac.uk/efo/EFO_0005260 GCST90044863 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to azacytidine 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 0 response to antineoplastic agent http://purl.obolibrary.org/obo/GO_0097327 GCST90044864 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to cladaribine 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 2 response to antineoplastic agent http://purl.obolibrary.org/obo/GO_0097327 GCST90044865 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to cytosine beta-D-arabinoside 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 0 response to cytosine arabinoside http://www.ebi.ac.uk/efo/EFO_0005655 GCST90044866 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to fludarabine 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 0 response to antineoplastic agent http://purl.obolibrary.org/obo/GO_0097327 GCST90044867 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to cytidine analogues (gemcitabine) 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 4 response to gemcitabine http://purl.obolibrary.org/obo/GO_0036272 GCST90044868 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to 5-fluorouracil 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 0 response to fluoropyrimidines http://www.ebi.ac.uk/efo/EFO_0010825 GCST90044869 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to fluoro-deoxyuridine 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 2 response to fluoropyrimidines http://www.ebi.ac.uk/efo/EFO_0010825 GCST90044870 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to arsenic trioxide 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 2 response to antineoplastic agent http://purl.obolibrary.org/obo/GO_0097327 GCST90044871 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to platinum-based chemotherapy (carboplatin) 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 1 response to carboplatin http://purl.obolibrary.org/obo/GO_0097328 GCST90044872 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to oxaliplatin 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 3 response to platinum based chemotherapy http://www.ebi.ac.uk/efo/EFO_0004647 GCST90044873 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to apatinib 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 0 response to tyrosine kinase inhibitor http://www.ebi.ac.uk/efo/EFO_0009170 GCST90044874 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to axitinib 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 0 response to tyrosine kinase inhibitor http://www.ebi.ac.uk/efo/EFO_0009170 GCST90044875 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to cabozantinib 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 0 response to tyrosine kinase inhibitor http://www.ebi.ac.uk/efo/EFO_0009170 GCST90044876 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to crizotinib 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 0 response to tyrosine kinase inhibitor http://www.ebi.ac.uk/efo/EFO_0009170 GCST90044877 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to dasatinib 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 0 response to tyrosine kinase inhibitor http://www.ebi.ac.uk/efo/EFO_0009170 GCST90044878 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to dovitinib 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 2 response to tyrosine kinase inhibitor http://www.ebi.ac.uk/efo/EFO_0009170 GCST90044879 Genome-wide genotyping array 680 2021-11-01 34437536 Akhtari FS 2021-08-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/34437536 High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Response to erlotinib 680 lymphoblastoid cell lines from Han Chinese ancestry, Japanese ancestry, Kenyan ancestry, Mexican ancestry, Tuscan ancestry, Yoruban ancestry, British ancestry, Columbian ancestry individuals NA Illumina [1510701] 9 response to erlotinib http://www.ebi.ac.uk/efo/EFO_0007868 GCST90044880 Genome-wide genotyping array 680 2021-11-05 33888571 Lee S 2021-04-22 Thorax www.ncbi.nlm.nih.gov/pubmed/33888571 Novel recessive locus for body mass index in childhood asthma. Body mass index in childhood asthma 892 Hispanic or Latin American trios 216 European ancestry trios, 28 African American trios, 19 Latin American trios, 23 trios NR [8689950] 1 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST90052899 Genome-wide sequencing 892 2021-11-05 33888571 Lee S 2021-04-22 Thorax www.ncbi.nlm.nih.gov/pubmed/33888571 Novel recessive locus for body mass index in childhood asthma. Body mass index in childhood asthma 892 Hispanic or Latin American trios 216 European ancestry trios, 28 African American trios, 19 Latin American ancestry trios, 23 trios NR [8689950] 0 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST90052900 Genome-wide sequencing 892 2019-04-03 30778226 Justice AE 2019-02-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30778226 Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Waist-to-hip ratio adjusted for BMI (recessive genetic model) 288,492 European ancestry individuals, up to 15,687 African American individuals, up to 29,315 South Asian ancestry individuals, up to 6,800 East Asian ancestry individuals, up to 4,075 Hispanic ancestry individuals 132,177 European ancestry individuals Affymetrix, Illumina [at least 228985] 1 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST007484 Genome-wide genotyping array, Exome genotyping array 344369 2019-04-03 30778226 Justice AE 2019-02-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30778226 Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Waist-to-hip ratio adjusted for BMI (additive genetic model) 288,492 European ancestry individuals 132,177 European ancestry individuals Affymetrix, Illumina [at least 228985] 56 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST007487 Genome-wide genotyping array, Exome genotyping array 288492 2019-04-03 30778226 Justice AE 2019-02-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30778226 Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Waist-to-hip ratio adjusted for BMI (additive genetic model) 288,492 European ancestry individuals, up to 15,687 African American individuals, up to 29,315 South Asian ancestry individuals, up to 6,800 East Asian ancestry individuals, up to 4,075 Hispanic ancestry individuals 132,177 European ancestry individuals Affymetrix, Illumina [at least 228985] 57 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST007483 Genome-wide genotyping array, Exome genotyping array 344369 2019-04-03 30778226 Justice AE 2019-02-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30778226 Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Waist-to-hip ratio adjusted for BMI (recessive genetic model) 288,492 European ancestry individuals 132,177 European ancestry individuals Affymetrix, Illumina [at least 228985] 2 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST007491 Genome-wide genotyping array, Exome genotyping array 288492 2019-04-03 30778226 Justice AE 2019-02-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30778226 Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Waist-to-hip ratio adjusted for BMI (additive genetic model) up to 130,976 European ancestry men, up to 164,238 African American, South Asian, East Asian and Hispanic ancestry men up to 62,500 European ancestry men Affymetrix, Illumina [at least 228985] 18 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST007492 Genome-wide genotyping array, Exome genotyping array 295214 2019-04-03 30778226 Justice AE 2019-02-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30778226 Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Waist-to-hip ratio adjusted for BMI (recessive genetic model) up to 130,976 European ancestry men, up to 164,238 African American, South Asian, East Asian and Hispanic ancestry men up to 62,500 European ancestry men Affymetrix, Illumina [at least 228985] 1 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST007493 Genome-wide genotyping array, Exome genotyping array 295214 2019-04-03 30778226 Justice AE 2019-02-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30778226 Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Waist-to-hip ratio adjusted for BMI (additive genetic model) up to 130,976 European ancestry men up to 62,500 European ancestry men Affymetrix, Illumina [at least 228985] 17 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST007494 Genome-wide genotyping array, Exome genotyping array 130976 2019-04-03 30778226 Justice AE 2019-02-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30778226 Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Waist-to-hip ratio adjusted for BMI (recessive genetic model) up to 130,976 European ancestry men up to 62,500 European ancestry men Affymetrix, Illumina [at least 228985] 1 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST007496 Genome-wide genotyping array, Exome genotyping array 130976 2019-04-03 30778226 Justice AE 2019-02-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30778226 Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Waist-to-hip ratio adjusted for BMI (additive genetic model) up to 157,516 European ancestry women, up to 180,131 African American, South Asian, East Asian and Hispanic ancestry women up to 62,368 European ancestry women Affymetrix, Illumina [at least 228985] 47 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST007500 Genome-wide genotyping array, Exome genotyping array 337647 2019-04-03 30778226 Justice AE 2019-02-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30778226 Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Waist-to-hip ratio adjusted for BMI (recessive genetic model) up to 157,516 European ancestry women, up to 180,131 African American, South Asian, East Asian and Hispanic ancestry women up to 62,368 European ancestry women Affymetrix, Illumina [~ 228985] 2 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST007501 Genome-wide genotyping array, Exome genotyping array 337647 2019-04-03 30778226 Justice AE 2019-02-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30778226 Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Waist-to-hip ratio adjusted for BMI (additive genetic model) up to 157,516 European ancestry women up to 62,368 European ancestry women Affymetrix, Illumina [at least 228985] 43 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST007502 Genome-wide genotyping array, Exome genotyping array 157516 2019-04-03 30778226 Justice AE 2019-02-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30778226 Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Waist-to-hip ratio adjusted for BMI (recessive genetic model) up to 157,516 European ancestry women up to 62,368 European ancestry women Affymetrix, Illumina [at least 228985] 2 BMI-adjusted waist-hip ratio http://www.ebi.ac.uk/efo/EFO_0007788 GCST007503 Genome-wide genotyping array, Exome genotyping array 157516 2019-01-21 30104601 Ren H 2018-08-13 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/30104601 Genes associated with anhedonia: a new analysis in a large clinical trial (GENDEP). Anhedonia in major depressive disorder 759 European ancestry individuals 1,351 individuals Illumina [1313315] (imputed) 0 anhedonia measurement http://www.ebi.ac.uk/efo/EFO_0009587 GCST006927 Genome-wide genotyping array 759 2018-10-09 30108209 Ganjgahi H 2018-08-14 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30108209 Fast and powerful genome wide association of dense genetic data with high dimensional imaging phenotypes. Brain imaging measurements 175 European ancestry schizophrenia cases, 155 European ancestry controls NA NR [1376877] 0 neuroimaging measurement http://www.ebi.ac.uk/efo/EFO_0004346 GCST006389 Genome-wide genotyping array 330 2019-02-13 30111768 Yao C 2018-08-15 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30111768 Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease. Blood protein levels 6861 European ancestry individuals 4298 European ancestry individuals Affymetrix, Illumina [8509364] (imputed) 8 blood protein measurement http://www.ebi.ac.uk/efo/EFO_0007937 GCST007128 Genome-wide genotyping array 6861 2018-11-01 30130595 Dominguez-Cruz MG 2018-08-18 Gene www.ncbi.nlm.nih.gov/pubmed/30130595 Pilot genome-wide association study identifying novel risk loci for type 2 diabetes in a Maya population. Type 2 diabetes 45 Maya ancestry cases, 47 Maya ancestry controls NA Affymetrix [757439] 24 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST006484 Genome-wide genotyping array 92 2018-10-18 30134803 Matana A 2018-04-11 Mol Med www.ncbi.nlm.nih.gov/pubmed/30134803 Genome-wide meta-analysis identifies novel loci associated with parathyroid hormone level. Plasma parathyroid hormone levels 806 Korculan (founder/genetic isolate) individuals, 831 Vis (founder/genetic isolate) individuals, 959 Croatian ancestry individuals NA Illumina [7411206] (imputed) 30 parathyroid hormone measurement http://www.ebi.ac.uk/efo/EFO_0004752 GCST006431 Genome-wide genotyping array 2596 2018-10-16 30134085 Zhang H 2018-07-01 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/30134085 Genome-wide association study of cognitive flexibility assessed by the Wisconsin Card Sorting Test. Cognitive flexibility 2,589 African American individuals, 2,284 European ancestry individuals NA Illumina [9722417] (imputed) 5 executive function measurement http://www.ebi.ac.uk/efo/EFO_0009332 GCST006406 Genome-wide genotyping array 4873 2018-11-29 30134952 Traglia M 2018-08-22 Genome Med www.ncbi.nlm.nih.gov/pubmed/30134952 Cross-genetic determination of maternal and neonatal immune mediators during pregnancy. Midgestational cytokine/chemokine levels (maternal genetic effect) 790 Hispanic, European, Asian, South Asian or African American individuals NA Affymetrix [629686] 3 gestational serum measurement, protein measurement, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0007964, http://www.ebi.ac.uk/efo/EFO_0004747, http://www.ebi.ac.uk/efo/EFO_0005939 GCST006621 Genome-wide genotyping array 790 2018-11-29 30134952 Traglia M 2018-08-22 Genome Med www.ncbi.nlm.nih.gov/pubmed/30134952 Cross-genetic determination of maternal and neonatal immune mediators during pregnancy. Neonatal cytokine/chemokine levels (maternal genetic effect) 790 Hispanic, European, Asian, South Asian or African American individuals NA Affymetrix [629686] 3 protein measurement, parental genotype effect measurement http://www.ebi.ac.uk/efo/EFO_0004747, http://www.ebi.ac.uk/efo/EFO_0005939 GCST006625 Genome-wide genotyping array 790 2018-11-29 30134952 Traglia M 2018-08-22 Genome Med www.ncbi.nlm.nih.gov/pubmed/30134952 Cross-genetic determination of maternal and neonatal immune mediators during pregnancy. Midgestational cytokine/chemokine levels (fetal genetic effect) 764 Hispanic, European, Asian, South Asian or African American individuals NA Affymetrix [622716] 1 gestational serum measurement, fetal genotype effect measurement, protein measurement http://www.ebi.ac.uk/efo/EFO_0007964, http://www.ebi.ac.uk/efo/EFO_0007959, http://www.ebi.ac.uk/efo/EFO_0004747 GCST006623 Genome-wide genotyping array 764 2018-11-29 30134952 Traglia M 2018-08-22 Genome Med www.ncbi.nlm.nih.gov/pubmed/30134952 Cross-genetic determination of maternal and neonatal immune mediators during pregnancy. Neonatal cytokine/chemokine levels (fetal genetic effect) 764 Hispanic, European, Asian, South Asian or African American individuals NA Affymetrix [622716] 23 fetal genotype effect measurement, protein measurement http://www.ebi.ac.uk/efo/EFO_0007959, http://www.ebi.ac.uk/efo/EFO_0004747 GCST006622 Genome-wide genotyping array 764 2018-11-01 30152087 Ostrom QT 2018-08-27 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/30152087 Age-specific genome-wide association study in glioblastoma identifies increased proportion of 'lower grade glioma'-like features associated with younger age. Glioblastoma (age-stratified) 1,533 cases diagnosed below median age, 1,476 cases diagnosed at median age, 1,503 cases diagnosed above median age, 10,582 controls, NA NR [NR] (imputed) 20 age at onset, glioblastoma multiforme http://www.ebi.ac.uk/efo/EFO_0004847, http://www.ebi.ac.uk/efo/EFO_0000519 GCST006480 Genome-wide genotyping array 15094 2018-10-17 30158200 Trajanoska K 2018-08-29 BMJ www.ncbi.nlm.nih.gov/pubmed/30158200 Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study. Fractures 37,857 European or East Asian cases, 227,116 European or East Asian controls 147,200 European ancestry cases, 150,085 European ancestry controls Affymetrix, Illumina [2539801] (imputed) 17 bone fracture http://www.ebi.ac.uk/efo/EFO_0003931 GCST006423 Genome-wide genotyping array 264973 2018-10-17 30158200 Trajanoska K 2018-08-29 BMJ www.ncbi.nlm.nih.gov/pubmed/30158200 Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study. Fractures 37,857 European or East Asian ancestry cases, 227,116 European or East Asian ancestry controls 18,779 European, East Asian or other ancestry cases, 32,078 European, East Asian or other ancestry controls Affymetrix, Illumina [2539801] (imputed) 5 bone fracture http://www.ebi.ac.uk/efo/EFO_0003931 GCST006422 Genome-wide genotyping array 264973 2018-10-17 30150663 Pasman JA 2018-08-27 Nat Neurosci www.ncbi.nlm.nih.gov/pubmed/30150663 GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia. Cannabis use 184,765 European ancestry individuals NA Affymetrix, Illumina [11733371] (imputed) 8 Cannabis use http://www.ebi.ac.uk/efo/EFO_0007585 GCST006421 Genome-wide genotyping array 184765 2018-10-17 30089514 Chen JA 2018-08-08 Mol Neurodegener www.ncbi.nlm.nih.gov/pubmed/30089514 Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases. Progressive supranuclear palsy 1,646 European ancestry cases, 10,662 European ancestry controls NA Illumina [6419662] (imputed) 13 Progressive supranuclear palsy http://www.orpha.net/ORDO/Orphanet_683 GCST006418 Genome-wide genotyping array 12308 2018-11-05 30120429 Schlauch KA 2018-08-17 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/30120429 Single-nucleotide polymorphisms in a cohort of significantly obese women without cardiometabolic diseases. Obesity without metabolic disease 38 European ancestry cases, 32 European ancestry non-obese controls NA Affymetrix [710007] 14 metabolically healthy obesity http://www.ebi.ac.uk/efo/EFO_0009382 GCST006492 Genome-wide genotyping array 70 2018-10-05 30099483 Hwangbo Y 2018-08-06 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/30099483 Genome-wide Association Study Reveals Distinct Genetic Susceptibility of Thyroid Nodules from Thyroid Cancer. Thyroid nodules 811 Korean ancestry cases, 691 Korean ancestry controls 1,981 Korean ancestry cases, 3,100 Korean ancestry controls Affymetrix [3996558] (imputed) 2 thyroid nodule http://www.ebi.ac.uk/efo/EFO_1001436 GCST006387 Genome-wide genotyping array 1502 2018-10-18 30103242 Karhausen JA 2018-08-13 Thromb Haemost www.ncbi.nlm.nih.gov/pubmed/30103242 Genome-Wide Association Study Links Receptor Tyrosine Kinase Inhibitor Sprouty 2 to Thrombocytopenia after Coronary Artery Bypass Surgery. Thrombocytopenia in coronary artery bypass surgery 176 European ancestry cases, 268 European ancestry cases 76 European ancestry cases, 70 European ancestry cases Illumina [525066] 1 Thrombocytopenia http://purl.obolibrary.org/obo/HP_0001873 GCST006435 Genome-wide genotyping array 444 2018-10-19 30113228 Torgerson DG 2018-08-16 Am J Physiol Lung Cell Mol Physiol www.ncbi.nlm.nih.gov/pubmed/30113228 Ancestry and Genetic Associations with Bronchopulmonary Dysplasia in Preterm Infants. Bronchopulmonary dysplasia in preterm infants 136 European ancestry cases, 82 African American cases, 28 Hispanic cases, 41 European ancestry controls, 51 African American controls, 14 Hispanic controls NA Affymetrix [8800000] (imputed) 12 Bronchopulmonary dysplasia http://www.orpha.net/ORDO/Orphanet_70589 GCST006460 Genome-wide genotyping array 352 2019-01-07 30102679 Hara M 2018-08-10 Med Sci Sports Exerc www.ncbi.nlm.nih.gov/pubmed/30102679 Genome-wide Association Study of Leisure-Time Exercise Behavior in Japanese Adults. Leisure-time exercise behaviour 1,789 Japanese ancestry physically active cases, 12,191 Japanese ancestry physically inactive controls 250 Japanese ancestry physically active cases, 1,786 Japanese ancestry physically inactive controls Illumina [up to 7094228] (imputed) 2 exercise http://www.ebi.ac.uk/efo/EFO_0000483 GCST006857 Genome-wide genotyping array 13980 2019-01-07 30102679 Hara M 2018-08-10 Med Sci Sports Exerc www.ncbi.nlm.nih.gov/pubmed/30102679 Genome-wide Association Study of Leisure-Time Exercise Behavior in Japanese Adults. Leisure-time exercise behaviour (age-stratified) 6,749 Japanese ancestry active and inactive individuals aged over 56, 7,231 Japanese ancestry active and inactive individuals aged under 56 1,129 Japanese ancestry active and inactive individuals aged over 56, 907 Japanese ancestry active and inactive individuals aged under 56 Illumina [up to 7094228] (imputed) 3 exercise http://www.ebi.ac.uk/efo/EFO_0000483 GCST006858 Genome-wide genotyping array 14092 2018-10-09 30102696 Chen Y 2018-08-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/30102696 A genome-wide association study identifies a susceptibility locus for biliary atresia on 2p16.1 within the gene EFEMP1. Biliary atresia 343 European ancestry cases, 1,716 European ancestry controls 156 European ancestry cases, 212 European ancestry controls Illumina [1171073] (imputed) 3 Biliary atresia http://www.orpha.net/ORDO/Orphanet_30391 GCST006390 Genome-wide genotyping array 2059 2019-08-07 30104761 Zhou W 2018-08-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30104761 Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies. Thyroid cancer 358 European ancestry cases, 407,399 European ancestry controls NA Affymetrix [28000000] (imputed) 1 thyroid carcinoma http://www.ebi.ac.uk/efo/EFO_0002892 GCST008371 Genome-wide genotyping array 407757 2019-08-07 30104761 Zhou W 2018-08-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30104761 Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies. Coronary artery disease 31,355 European ancestry cases, 377,103 European ancestry controls NA Affymetrix [28000000] (imputed) 40 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST008370 Genome-wide genotyping array 408458 2019-08-07 30104761 Zhou W 2018-08-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30104761 Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies. Glaucoma 4,462 European ancestry cases, 397,761 European ancestry controls NA Affymetrix [28000000] (imputed) 11 glaucoma http://www.ebi.ac.uk/efo/EFO_0000516 GCST008373 Genome-wide genotyping array 402223 2019-08-07 30104761 Zhou W 2018-08-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/30104761 Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies. Colorectal cancer 4,562 European ancestry cases, 382,756 European ancestry controls NA Affymetrix [28000000] (imputed) 3 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST008372 Genome-wide genotyping array 387318 2019-01-21 30134812 Chattopadhyay S 2018-06-11 Mol Med www.ncbi.nlm.nih.gov/pubmed/30134812 Enrichment of B cell receptor signaling and epidermal growth factor receptor pathways in monoclonal gammopathy of undetermined significance: a genome-wide genetic interaction study. Monoclonal gammopathy of undetermined significance 243 German ancestry cases, 1,285 German ancestry controls NA Illumina [489555] 15 monoclonal gammopathy http://www.ebi.ac.uk/efo/EFO_0000203 GCST006917 Genome-wide genotyping array 1528 2019-01-08 30132804 Kim M 2018-08-22 Clin Genet www.ncbi.nlm.nih.gov/pubmed/30132804 APOA5 Variants are Associated with Decreased Adiponectin Levels and Increased Arterial Stiffness in Subjects with Low HDL-cholesterol Levels. Low HDL-cholesterol levels 612 Korean ancestry cases, 1,536 Korean ancestry controls NA Affymetrix [394411] 0 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST006860 Genome-wide genotyping array 2148 2018-11-05 30160337 Asleh R 2018-08-30 Clin Transplant www.ncbi.nlm.nih.gov/pubmed/30160337 Genome Wide Association Study Reveals Novel Genetic Loci Associated With Change in Renal Function in Heart Transplant Recipients. Glomerular filtration rate change in heart transplantation 243 European ancestry individuals, 1 American Indian ancestry individual, 7 individuals NA Illumina [314903] (imputed) 5 response to transplant, GFR change measurement http://www.ebi.ac.uk/efo/EFO_0007043, http://www.ebi.ac.uk/efo/EFO_0006829 GCST006496 Genome-wide genotyping array 251 2019-04-09 30529582 Lu Y 2018-12-06 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/30529582 Large-scale Genome-wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer. Colorectal cancer 22,775 East Asian ancestry cases, 47,731 East Asian ancestry controls NA Affymetrix, Illumina [up to 10700000] (imputed) 40 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST007552 Genome-wide genotyping array, Exome genotyping array 70506 2019-02-27 30531935 Crowley JJ 2018-12-07 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30531935 Common-variant associations with fragile X syndrome. Fragile X syndrome 80 European ancestry male cases, 9 male cases, 266 European ancestry male controls NA Illumina [750000] 1 Fragile X syndrome http://www.orpha.net/ORDO/Orphanet_908 GCST007233 Genome-wide genotyping array 355 2019-10-24 31135556 Wyles CC 2019-05-13 Clin Orthop Relat Res www.ncbi.nlm.nih.gov/pubmed/31135556 CORR® ORS Richard A. Brand Award: Disruption in Peroxisome Proliferator-Activated Receptor-γ (PPARG) Increases Osteonecrosis Risk Through Genetic Variance and Pharmacologic Modulation. Idiopathic osteonecrosis of the femoral head 3 African American cases, 1 Asian ancestry case, 98 European ancestry cases, 6 African American controls, 1 Asian ancestry control, 4,118 European ancestry controls 1 African American case, 1 Asian ancestry case, 36 European ancestry cases, 1 African American control, 2 Asian ancestry controls, 461 European ancestry controls Illumina [NR] (imputed) 1 idiopathic osteonecrosis of the femoral head http://www.ebi.ac.uk/efo/EFO_1001930 GCST008913 Genome-wide genotyping array 4227 2019-02-06 30552173 Aterido A 2018-12-14 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/30552173 Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasis. Psoriatic arthritis 744 Spanish ancestry cases, 1,454 Spanish ancestry controls 1,430 cases, 1,417 controls Illumina [1387382] (imputed) 38 psoriatic arthritis http://www.ebi.ac.uk/efo/EFO_0003778 GCST007043 Genome-wide genotyping array 2198 2019-08-05 31123309 Rayner C 2019-05-23 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31123309 A genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders. Response to cognitive-behavioural therapy in anxiety and major depressive disorders 972 European ancestry adult anxiety disorder cases, 832 adult major depressive disorder cases, 920 child anxiety disorder cases NA Illumina [4710000] (imputed) 3 cognitive behavioural therapy http://www.ebi.ac.uk/efo/EFO_0007820 GCST008358 Genome-wide genotyping array 2724 2019-08-05 31123309 Rayner C 2019-05-23 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31123309 A genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders. Response to cognitive-behavioural therapy in anxiety disorder 920 child cases NA Illumina [at least 4710000] (imputed) 10 cognitive behavioural therapy http://www.ebi.ac.uk/efo/EFO_0007820 GCST008359 Genome-wide genotyping array 920 2019-08-05 31123309 Rayner C 2019-05-23 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31123309 A genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders. Response to cognitive-behavioural therapy in anxiety disorder 972 European ancestry adult cases NA Illumina [at least 4710000] (imputed) 6 cognitive behavioural therapy http://www.ebi.ac.uk/efo/EFO_0007820 GCST008360 Genome-wide genotyping array 972 2019-08-05 31123309 Rayner C 2019-05-23 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/31123309 A genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders. Response to cognitive-behavioural therapy in major depressive disorder 832 adult cases NA Illumina [at least 4710000] (imputed) 9 cognitive behavioural therapy http://www.ebi.ac.uk/efo/EFO_0007820 GCST008361 Genome-wide genotyping array 832 2019-06-26 29459680 Claes P 2018-02-19 Nat Genet www.ncbi.nlm.nih.gov/pubmed/29459680 Genome-wide mapping of global-to-local genetic effects on human facial shape. Facial morphology traits (63 three-dimensional facial segments) 2,329 European ancestry individuals 1,719 European ancestry individuals Illumina [9478608] (imputed) 10 facial morphology measurement http://www.ebi.ac.uk/efo/EFO_0007841 GCST007989 Genome-wide genotyping array 2329 2019-07-25 31127053 Tang Y 2019-05-24 Diabetes www.ncbi.nlm.nih.gov/pubmed/31127053 A Genetic Locus on Chromosome 2q24 Predicting Peripheral Neuropathy Risk in Type 2 Diabetes: Results From the ACCORD and BARI 2D Studies. Diabetic peripheral neuropathy in type 2 diabetes 4,384 European ancestry cases, 784 European ancestry controls 791 European ancestry cases, 158 European ancestry controls, 1,345 African American individuals Affymetrix, Illumina [6847206] (imputed) 5 peripheral neuropathy http://www.ebi.ac.uk/efo/EFO_0003100 GCST008223 Genome-wide genotyping array 5168 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Alanine levels 86,413 European ancestry individuals NA Affymetrix, Illumina [6052021] (imputed) 0 alanine measurement http://www.ebi.ac.uk/efo/EFO_0009765 GCST90010722 Genome-wide genotyping array 86413 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Methioninesulfoxide levels 23,469 European ancestry individuals NA Affymetrix, Illumina [6093711] (imputed) 0 blood metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005664 GCST90010748 Genome-wide genotyping array 23469 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. trans-Hydroxyproline levels 30,895 European ancestry individuals NA Affymetrix, Illumina [6046415] (imputed) 0 blood metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005664 GCST90010749 Genome-wide genotyping array 30895 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Citrulline levels 30,940 European ancestry individuals NA Affymetrix, Illumina [6046410] (imputed) 0 citrulline measurement http://www.ebi.ac.uk/efo/EFO_0009777 GCST90010726 Genome-wide genotyping array 30940 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Glutamine levels 85,821 European ancestry individuals NA Affymetrix, Illumina [6051950] (imputed) 0 glutamine measurement http://www.ebi.ac.uk/efo/EFO_0009768 GCST90010727 Genome-wide genotyping array 85821 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Spermidine levels 16,699 European ancestry individuals NA Affymetrix, Illumina [6090968] (imputed) 0 blood metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005664 GCST90010751 Genome-wide genotyping array 16699 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Glycine levels 80,003 European ancestry individuals NA Affymetrix, Illumina [6053131] (imputed) 0 glycine measurement http://www.ebi.ac.uk/efo/EFO_0009767 GCST90010729 Genome-wide genotyping array 80003 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Histidine levels 80,809 European ancestry individuals NA Affymetrix, Illumina [6053918] (imputed) 0 histidine measurement http://www.ebi.ac.uk/efo/EFO_0009769 GCST90010730 Genome-wide genotyping array 80809 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Isoleucine levels 86,404 European ancestry individuals NA Affymetrix, Illumina [6052093] (imputed) 0 isoleucine measurement http://www.ebi.ac.uk/efo/EFO_0009793 GCST90010731 Genome-wide genotyping array 86404 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Leucine levels 86,351 European ancestry individuals NA Affymetrix, Illumina [6052280] (imputed) 0 leucine measurement http://www.ebi.ac.uk/efo/EFO_0009770 GCST90010732 Genome-wide genotyping array 86351 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Lysine levels 30,982 European ancestry individuals NA Affymetrix, Illumina [6046356] (imputed) 0 lysine measurement http://www.ebi.ac.uk/efo/EFO_0005002 GCST90010733 Genome-wide genotyping array 30982 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Propionylcarnitine levels 32,590 European ancestry individuals NA Affymetrix, Illumina [6045556] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010755 Genome-wide genotyping array 32590 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phenylalanine levels 84,297 European ancestry individuals NA Affymetrix, Illumina [6055439] (imputed) 0 phenylalanine measurement http://www.ebi.ac.uk/efo/EFO_0005001 GCST90010736 Genome-wide genotyping array 84297 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Proline levels 30,985 European ancestry individuals NA Affymetrix, Illumina [6046366] (imputed) 0 proline measurement http://www.ebi.ac.uk/efo/EFO_0009773 GCST90010737 Genome-wide genotyping array 30985 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Serine levels 30,955 European ancestry individuals NA Affymetrix, Illumina [6046388] (imputed) 0 serine measurement http://www.ebi.ac.uk/efo/EFO_0009774 GCST90010738 Genome-wide genotyping array 30955 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Threonine levels 29,276 European ancestry individuals NA Affymetrix, Illumina [6042426] (imputed) 0 threonine measurement http://www.ebi.ac.uk/efo/EFO_0009775 GCST90010739 Genome-wide genotyping array 29276 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Hexanoylcarnitine levels 9,363 European ancestry individuals NA Affymetrix, Illumina [6083013] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010759 Genome-wide genotyping array 9363 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Pimelylcarnitine levels 15,119 European ancestry individuals NA Affymetrix, Illumina [6083180] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010760 Genome-wide genotyping array 15119 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Octanoylcarnitine levels 31,969 European ancestry individuals NA Affymetrix, Illumina [6043492] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010761 Genome-wide genotyping array 31969 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Acetylornithine levels 30,692 European ancestry individuals NA Affymetrix, Illumina [6046508] (imputed) 0 blood metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005664 GCST90010743 Genome-wide genotyping array 30692 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Symmetric dimethylarginine levels 9,256 European ancestry individuals NA Affymetrix, Illumina [6083518] (imputed) 0 symmetrical dimethylarginine measurement http://www.ebi.ac.uk/efo/EFO_0006523 GCST90010744 Genome-wide genotyping array 9256 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Dodecenoylcarnitine levels 16,839 European ancestry individuals NA Affymetrix, Illumina [5791491] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010766 Genome-wide genotyping array 16839 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Tetradecanoylcarnitine levels 23,445 European ancestry individuals NA Affymetrix, Illumina [6093394] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010767 Genome-wide genotyping array 23445 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Creatinine levels 84,794 European ancestry individuals NA Affymetrix, Illumina [6050906] (imputed) 0 creatinine measurement http://www.ebi.ac.uk/efo/EFO_0004518 GCST90010746 Genome-wide genotyping array 84794 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Kynurenine levels 30,899 European ancestry individuals NA Affymetrix, Illumina [6046416] (imputed) 0 kynurenine measurement http://www.ebi.ac.uk/efo/EFO_0008529 GCST90010747 Genome-wide genotyping array 30899 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Arginine levels 30,724 European ancestry individuals NA Affymetrix, Illumina [6046728] (imputed) 0 L-arginine measurement http://www.ebi.ac.uk/efo/EFO_0006524 GCST90010723 Genome-wide genotyping array 30724 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Asparagine levels 30,922 European ancestry individuals NA Affymetrix, Illumina [6046450] (imputed) 0 asparagine measurement http://www.ebi.ac.uk/efo/EFO_0009766 GCST90010724 Genome-wide genotyping array 30922 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Aspartate levels 30,775 European ancestry individuals NA Affymetrix, Illumina [6046296] (imputed) 0 aspartate measurement http://www.ebi.ac.uk/efo/EFO_0010462 GCST90010725 Genome-wide genotyping array 30775 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Sarcosine levels 22,912 European ancestry individuals NA Affymetrix, Illumina [6093787] (imputed) 0 blood metabolite measurement http://www.ebi.ac.uk/efo/EFO_0005664 GCST90010750 Genome-wide genotyping array 22912 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Glutamate levels 30,977 European ancestry individuals NA Affymetrix, Illumina [6046372] (imputed) 0 glutamate measurement http://www.ebi.ac.uk/efo/EFO_0010487 GCST90010728 Genome-wide genotyping array 30977 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Taurine levels 23,553 European ancestry individuals NA Affymetrix, Illumina [6093547] (imputed) 0 taurine measurement http://www.ebi.ac.uk/efo/EFO_0010536 GCST90010752 Genome-wide genotyping array 23553 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Carnitine levels 31,001 European ancestry individuals NA Affymetrix, Illumina [6046392] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010753 Genome-wide genotyping array 31001 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Acetylcarnitine levels 31,008 European ancestry individuals NA Affymetrix, Illumina [6046365] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010754 Genome-wide genotyping array 31008 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Methionine levels 30,967 European ancestry individuals NA Affymetrix, Illumina [6046489] (imputed) 0 methionine measurement http://www.ebi.ac.uk/efo/EFO_0009771 GCST90010734 Genome-wide genotyping array 30967 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Ornithine levels 30,920 European ancestry individuals NA Affymetrix, Illumina [6046416] (imputed) 0 ornithine measurement http://www.ebi.ac.uk/efo/EFO_0009776 GCST90010735 Genome-wide genotyping array 30920 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Butyrylcarnitine levels 30,694 European ancestry individuals NA Affymetrix, Illumina [6046389] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010756 Genome-wide genotyping array 30694 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Valerylcarnitine levels 9,363 European ancestry individuals NA Affymetrix, Illumina [6083606] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010757 Genome-wide genotyping array 9363 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Methylglutarylcarnitine levels 22,335 European ancestry individuals NA Affymetrix, Illumina [6093101] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010758 Genome-wide genotyping array 22335 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Tryptophan levels 30,974 European ancestry individuals NA Affymetrix, Illumina [6046425] (imputed) 0 tryptophan measurement http://www.ebi.ac.uk/efo/EFO_0008534 GCST90010740 Genome-wide genotyping array 30974 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Tyrosine levels 86,507 European ancestry individuals NA Affymetrix, Illumina [6036766] (imputed) 0 tyrosine measurement http://www.ebi.ac.uk/efo/EFO_0005058 GCST90010741 Genome-wide genotyping array 86507 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Valine levels 85,641 European ancestry individuals NA Affymetrix, Illumina [6051188] (imputed) 0 valine measurement http://www.ebi.ac.uk/efo/EFO_0009792 GCST90010742 Genome-wide genotyping array 85641 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Nonaylcarnitine levels 13,925 European ancestry individuals NA Affymetrix, Illumina [6083678] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010762 Genome-wide genotyping array 13925 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Decanoylcarnitine levels 31,934 European ancestry individuals NA Affymetrix, Illumina [6043651] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010763 Genome-wide genotyping array 31934 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Decenoylcarnitine levels 15,116 European ancestry individuals NA Affymetrix, Illumina [6083730] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010764 Genome-wide genotyping array 15116 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Dodecanoylcarnitine levels 28,569 European ancestry individuals NA Affymetrix, Illumina [6042902] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010765 Genome-wide genotyping array 28569 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. alpha-Aminoadipic acid levels 14,414 European ancestry individuals NA Affymetrix, Illumina [6077382] (imputed) 0 aminoadipic acid measurement http://www.ebi.ac.uk/efo/EFO_0010459 GCST90010745 Genome-wide genotyping array 14414 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Tetradecenoylcarnitine levels 31,105 European ancestry individuals NA Affymetrix, Illumina [6058849] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010768 Genome-wide genotyping array 31105 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Tetradecadienylcarnitine levels 15,118 European ancestry individuals NA Affymetrix, Illumina [6083929] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010769 Genome-wide genotyping array 15118 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Hexadecanoylcarnitine levels 30,915 European ancestry individuals NA Affymetrix, Illumina [6046326] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010770 Genome-wide genotyping array 30915 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Hexadecenoylcarnitine levels 14,370 European ancestry individuals NA Affymetrix, Illumina [6077273] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010771 Genome-wide genotyping array 14370 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Octadecanoylcarnitine levels 30,138 European ancestry individuals NA Affymetrix, Illumina [6039747] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010772 Genome-wide genotyping array 30138 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Octadecenoylcarnitine levels 15,967 European ancestry individuals NA Affymetrix, Illumina [6084364] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010773 Genome-wide genotyping array 15967 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Octadecandienylcarnitine levels 31,129 European ancestry individuals NA Affymetrix, Illumina [6058871] (imputed) 0 carnitine measurement http://www.ebi.ac.uk/efo/EFO_0010469 GCST90010774 Genome-wide genotyping array 31129 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. lysoPhosphatidylcholine acyl C14:0 levels 9,363 European ancestry individuals NA Affymetrix, Illumina [6083623] (imputed) 0 lysophosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010224 GCST90010775 Genome-wide genotyping array 9363 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. lysoPhosphatidylcholine acyl C16:1 levels 16,836 European ancestry individuals NA Affymetrix, Illumina [5791495] (imputed) 0 lysophosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010224 GCST90010776 Genome-wide genotyping array 16836 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. lysoPhosphatidylcholine acyl C17:0 levels 16,839 European ancestry individuals NA Affymetrix, Illumina [5791690] (imputed) 0 lysophosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010224 GCST90010777 Genome-wide genotyping array 16839 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. lysoPhosphatidylcholine acyl C18:0 levels 16,839 European ancestry individuals NA Affymetrix, Illumina [5792004] (imputed) 0 lysophosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010224 GCST90010778 Genome-wide genotyping array 16839 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. lysoPhosphatidylcholine acyl C18:2 levels 16,837 European ancestry individuals NA Affymetrix, Illumina [5791071] (imputed) 0 lysophosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010224 GCST90010779 Genome-wide genotyping array 16837 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. lysoPhosphatidylcholine acyl C20:4 levels 16,838 European ancestry individuals NA Affymetrix, Illumina [5791771] (imputed) 0 lysophosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010224 GCST90010780 Genome-wide genotyping array 16838 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. lysoPhosphatidylcholine acyl C26:1 levels 9,363 European ancestry individuals NA Affymetrix, Illumina [6083819] (imputed) 0 lysophosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010224 GCST90010781 Genome-wide genotyping array 9363 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. lysoPhosphatidylcholine acyl C16:0 levels 16,839 European ancestry individuals NA Affymetrix, Illumina [5792440] (imputed) 0 lysophosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010224 GCST90010782 Genome-wide genotyping array 16839 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. lysoPhosphatidylcholine acyl C18:1 levels 16,838 European ancestry individuals NA Affymetrix, Illumina [5791467] (imputed) 0 lysophosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010224 GCST90010783 Genome-wide genotyping array 16838 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. lysoPhosphatidylcholine acyl C20:3 levels 16,839 European ancestry individuals NA Affymetrix, Illumina [5792163] (imputed) 0 lysophosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010224 GCST90010784 Genome-wide genotyping array 16839 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. lysoPhosphatidylcholine acyl C24:0 levels 9,363 European ancestry individuals NA Affymetrix, Illumina [6083871] (imputed) 0 lysophosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010224 GCST90010785 Genome-wide genotyping array 9363 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. lysoPhosphatidylcholine acyl C26:0 levels 9,363 European ancestry individuals NA Affymetrix, Illumina [6083737] (imputed) 0 lysophosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010224 GCST90010786 Genome-wide genotyping array 9363 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. lysoPhosphatidylcholine acyl C28:0 levels 15,963 European ancestry individuals NA Affymetrix, Illumina [6084421] (imputed) 0 lysophosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010224 GCST90010787 Genome-wide genotyping array 15963 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. lysoPhosphatidylcholine acyl C28:1 levels 16,838 European ancestry individuals NA Affymetrix, Illumina [5792091] (imputed) 0 lysophosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010224 GCST90010788 Genome-wide genotyping array 16838 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C24:0 levels 13,184 European ancestry individuals NA Affymetrix, Illumina [6083416] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010789 Genome-wide genotyping array 13184 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C26:0 levels 9,363 European ancestry individuals NA Affymetrix, Illumina [6083682] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010790 Genome-wide genotyping array 9363 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. lysoPhosphatidylcholine acyl C28:0 levels 16,839 European ancestry individuals NA Affymetrix, Illumina [5791678] (imputed) 0 lysophosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010224 GCST90010791 Genome-wide genotyping array 16839 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C30:0 levels 16,838 European ancestry individuals NA Affymetrix, Illumina [5791235] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010792 Genome-wide genotyping array 16838 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C32:0 levels 16,838 European ancestry individuals NA Affymetrix, Illumina [5791755] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010793 Genome-wide genotyping array 16838 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C32:1 levels 16,837 European ancestry individuals NA Affymetrix, Illumina [5790467] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010794 Genome-wide genotyping array 16837 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C32:2 levels 16,839 European ancestry individuals NA Affymetrix, Illumina [5789893] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010795 Genome-wide genotyping array 16839 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C34:1 levels 16,838 European ancestry individuals NA Affymetrix, Illumina [5791930] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010796 Genome-wide genotyping array 16838 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C34:2 levels 16,839 European ancestry individuals NA Affymetrix, Illumina [5792223] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010797 Genome-wide genotyping array 16839 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C34:3 levels 16,839 European ancestry individuals NA Affymetrix, Illumina [5791551] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010798 Genome-wide genotyping array 16839 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C34:4 levels 16,839 European ancestry individuals NA Affymetrix, Illumina [5790991] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010799 Genome-wide genotyping array 16839 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C36:0 levels 16,839 European ancestry individuals NA Affymetrix, Illumina [5791651] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010800 Genome-wide genotyping array 16839 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C36:2 levels 16,839 European ancestry individuals NA Affymetrix, Illumina [5792013] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010801 Genome-wide genotyping array 16839 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C36:3 levels 16,838 European ancestry individuals NA Affymetrix, Illumina [5791858] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010802 Genome-wide genotyping array 16838 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C36:4 levels 16,839 European ancestry individuals NA Affymetrix, Illumina [5791936] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010803 Genome-wide genotyping array 16839 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C36:5 levels 16,835 European ancestry individuals NA Affymetrix, Illumina [5790837] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010804 Genome-wide genotyping array 16835 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C36:6 levels 16,837 European ancestry individuals NA Affymetrix, Illumina [5791314] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010805 Genome-wide genotyping array 16837 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C38:0 levels 16,839 European ancestry individuals NA Affymetrix, Illumina [5791519] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010806 Genome-wide genotyping array 16839 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C38:3 levels 16,838 European ancestry individuals NA Affymetrix, Illumina [5791226] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010807 Genome-wide genotyping array 16838 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C38:4 levels 16,837 European ancestry individuals NA Affymetrix, Illumina [5791386] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010808 Genome-wide genotyping array 16837 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C38:5 levels 16,836 European ancestry individuals NA Affymetrix, Illumina [5791436] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010809 Genome-wide genotyping array 16836 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C38:6 levels 16,838 European ancestry individuals NA Affymetrix, Illumina [5791244] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010810 Genome-wide genotyping array 16838 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C40:2 levels 16,719 European ancestry individuals NA Affymetrix, Illumina [5793499] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010811 Genome-wide genotyping array 16719 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C40:3 levels 16,431 European ancestry individuals NA Affymetrix, Illumina [5793014] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010812 Genome-wide genotyping array 16431 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C40:4 levels 16,835 European ancestry individuals NA Affymetrix, Illumina [5791955] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010813 Genome-wide genotyping array 16835 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C40:5 levels 16,835 European ancestry individuals NA Affymetrix, Illumina [5791407] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010814 Genome-wide genotyping array 16835 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C40:6 levels 16,837 European ancestry individuals NA Affymetrix, Illumina [5791022] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010815 Genome-wide genotyping array 16837 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C42:0 levels 16,118 European ancestry individuals NA Affymetrix, Illumina [5791949] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010816 Genome-wide genotyping array 16118 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C42:1 levels 16,570 European ancestry individuals NA Affymetrix, Illumina [5791842] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010817 Genome-wide genotyping array 16570 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C42:4 levels 16,611 European ancestry individuals NA Affymetrix, Illumina [5793588] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010818 Genome-wide genotyping array 16611 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C42:5 levels 16,508 European ancestry individuals NA Affymetrix, Illumina [5792227] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010819 Genome-wide genotyping array 16508 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine diacyl C42:6 levels 15,749 European ancestry individuals NA Affymetrix, Illumina [6084545] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010820 Genome-wide genotyping array 15749 2021-01-14 33414548 Lotta LA 2021-01-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33414548 A cross-platform approach identifies genetic regulators of human metabolism and health. Phosphatidylcholine acyl-alkyl C30:1 levels 9,003 European ancestry individuals NA Affymetrix, Illumina [6083739] (imputed) 0 phosphatidylcholine measurement http://www.ebi.ac.uk/efo/EFO_0010226 GCST90010821 Genome-wide genotyping array 9003 2019-01-28 30535121 Gao XR 2018-12-07 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/30535121 Genome-wide association analyses identify 139 loci associated with macular thickness in the UK Biobank cohort. Macular thickness 59,814 European ancestry individuals 8,609 European ancestry individuals Affymetrix [11100000] (imputed) 139 macula measurement http://www.ebi.ac.uk/efo/EFO_0008375 GCST006976 Genome-wide genotyping array 59814 2021-07-28 33495599 Johnson N 2021-01-26 Br J Cancer www.ncbi.nlm.nih.gov/pubmed/33495599 CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers. Estrone-3-glucuronide levels 560 European ancestry individuals NA Illumina [8280353] (imputed) 1 estrone conjugate measurement http://www.ebi.ac.uk/efo/EFO_0007971 GCST012151 Genome-wide genotyping array 560 2021-07-28 33495599 Johnson N 2021-01-26 Br J Cancer www.ncbi.nlm.nih.gov/pubmed/33495599 CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers. Pregnanediol-3-glucuronide levels 560 European ancestry individuals NA Illumina [8280353] (imputed) 0 sex hormone measurement http://www.ebi.ac.uk/efo/EFO_0011008 GCST012150 Genome-wide genotyping array 560 2020-09-12 32469969 Pott J 2020-05-29 PLoS One www.ncbi.nlm.nih.gov/pubmed/32469969 Genome-wide analysis of carotid plaque burden suggests a role of IL5 in men. Carotid plaque maximum area 727 European ancestry men, 550 European ancestry women NA Affymetrix [532676] (imputed) 14 carotid plaque build http://www.ebi.ac.uk/efo/EFO_0006501 GCST010536 Genome-wide genotyping array 1277 2020-09-12 32469969 Pott J 2020-05-29 PLoS One www.ncbi.nlm.nih.gov/pubmed/32469969 Genome-wide analysis of carotid plaque burden suggests a role of IL5 in men. Sum of carotid plaque area 727 European ancestry men, 550 European ancestry women NA Affymetrix [532676] (imputed) 13 carotid plaque build http://www.ebi.ac.uk/efo/EFO_0006501 GCST010538 Genome-wide genotyping array 1277 2020-09-12 32469969 Pott J 2020-05-29 PLoS One www.ncbi.nlm.nih.gov/pubmed/32469969 Genome-wide analysis of carotid plaque burden suggests a role of IL5 in men. Mean area of carotid plaque 727 European ancestry men, 550 European ancestry women NA Affymetrix [532676] (imputed) 9 carotid plaque build http://www.ebi.ac.uk/efo/EFO_0006501 GCST010537 Genome-wide genotyping array 1277 2020-09-12 32469969 Pott J 2020-05-29 PLoS One www.ncbi.nlm.nih.gov/pubmed/32469969 Genome-wide analysis of carotid plaque burden suggests a role of IL5 in men. Maximum stenosis 727 European ancestry men, 550 European ancestry women NA Affymetrix [532676] (imputed) 13 carotid plaque build http://www.ebi.ac.uk/efo/EFO_0006501 GCST010541 Genome-wide genotyping array 1277 2020-09-12 32469969 Pott J 2020-05-29 PLoS One www.ncbi.nlm.nih.gov/pubmed/32469969 Genome-wide analysis of carotid plaque burden suggests a role of IL5 in men. Mean degree of stenosis 727 European ancestry men, 550 European ancestry women NA Affymetrix [532676] (imputed) 11 carotid plaque build http://www.ebi.ac.uk/efo/EFO_0006501 GCST010540 Genome-wide genotyping array 1277 2020-09-12 32469969 Pott J 2020-05-29 PLoS One www.ncbi.nlm.nih.gov/pubmed/32469969 Genome-wide analysis of carotid plaque burden suggests a role of IL5 in men. Sum of stenosis 727 European ancestry men, 550 European ancestry women NA Affymetrix [532676] (imputed) 11 carotid plaque build http://www.ebi.ac.uk/efo/EFO_0006501 GCST010539 Genome-wide genotyping array 1277 2020-11-05 32554042 Jia X 2020-06-14 Kidney Int www.ncbi.nlm.nih.gov/pubmed/32554042 Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome. Childhood steroid-sensitive nephrotic syndrome 987 Japanese ancestry cases, 3,206 Japanese ancestry controls 249 Korean ancestry cases, 181 South Asian ancestry cases, 207 African ancestry cases, 307 European ancestry cases, 27 Hispanic cases, 85 Maghrebian ancestry cases, 3805 Korean ancestry controls, 8,255 South Asian ancestry controls, 5,657 African ancestry controls, 35,913 European ancestry controls, 5,789 Hispanic controls, 261 Moroccan ancestry controls Affymetrix [6834340] (imputed) 2 nephrotic syndrome http://www.ebi.ac.uk/efo/EFO_0004255 GCST010731 Genome-wide genotyping array 4193 2020-09-07 32460577 Song L 2020-05-28 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/32460577 Association of TIM-1 (T-Cell Immunoglobulin and Mucin Domain 1) With Incidence of Stroke. T-Cell Immunoglobulin and Mucin domain 1 levels 4,505 European ancestry individuals NA Illumina [7328171] (imputed) 8 T-cell immunoglobulin and mucin domain 1 measurement http://www.ebi.ac.uk/efo/EFO_0010812 GCST010500 Genome-wide genotyping array 4505 2020-07-21 32271837 Im SW 2020-04-09 PLoS One www.ncbi.nlm.nih.gov/pubmed/32271837 A population-specific low-frequency variant of SLC22A12 (p.W258*) explains nearby genome-wide association signals for serum uric acid concentrations among Koreans. Serum uric acid levels 1,902 Korean ancestry males 2,912 Korean ancestry individuals Illumina [4414664] (imputed) 2 uric acid measurement http://www.ebi.ac.uk/efo/EFO_0004761 GCST010283 Genome-wide genotyping array 1902 2020-06-16 23394302 Pechlivanis S 2013-02-08 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/23394302 Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study. Coronary artery calcification 2,158 Europen ancestry males, 2,171 European ancestry females NA Illumina [up to 196725] 4 coronary artery calcification http://www.ebi.ac.uk/efo/EFO_0004723 GCST010078 Targeted genotyping array [Metabochip] 4329 2020-02-18 31872073 Hosoda Y 2019-12-12 Commun Biol www.ncbi.nlm.nih.gov/pubmed/31872073 Genome-wide association analyses identify two susceptibility loci for pachychoroid disease central serous chorioretinopathy. Central serous retinopathy 610 Japanese ancestry cases, 2,850 Japanese ancestry controls 415 Japanese ancestry cases, 6,602 Japanese ancestry controls, 521 European ancestry cases, 3,577 European ancestry controls Illumina [2893743] (imputed) 4 central serous retinopathy http://www.ebi.ac.uk/efo/EFO_0009784 GCST009653 Genome-wide genotyping array 3460 2020-02-20 31872970 Harvey PD 2019-12-24 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/31872970 Genome-wide association study of cognitive performance in U.S. veterans with schizophrenia or bipolar disorder. Cognitive performance in schizophrenia or bipolar disorder 1,095 European ancestry individuals with schizophrenia, 2,864 European ancestry individuals with bipolar disorder, 1,594 African Americans with schizophrenia, 1,007 African Americans with bipolar disorder NA Affymetrix [up to 6007810] (imputed) 1 cognitive function measurement http://www.ebi.ac.uk/efo/EFO_0008354 GCST009678 Genome-wide genotyping array 6560 2020-04-17 29905830 Lee HS 2018-08-01 J Crohns Colitis www.ncbi.nlm.nih.gov/pubmed/29905830 An Intergenic Variant rs9268877 Between HLA-DRA and HLA-DRB Contributes to the Clinical Course and Long-term Outcome of Ulcerative Colitis. Poor prognosis in Crohn's disease 243 Korean ancestry poor prognosis cases, 364 Korean ancestry good prognosis controls 145 Korean ancestry poor prognosis cases, 129 Korean ancestry good prognosis controls Illumina [up to 519662] 1 disease prognosis measurement http://www.ebi.ac.uk/efo/EFO_0007936 GCST009878 Targeted genotyping array [ImmunoChip] 607 2020-02-20 31886626 Hettema JM 2019-12-30 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/31886626 Genome-wide association study of shared liability to anxiety disorders in Army STARRS. Anxiety disorder (factor score) 28,950 European ancestry individuals, 2,482 African American individuals, 3,264 Latino individuals NA Illumina [up to 10000000] (imputed) 2 anxiety disorder measurement http://www.ebi.ac.uk/efo/EFO_0007795 GCST009679 Genome-wide genotyping array 34696 2021-08-20 33654092 Shigemizu D 2021-03-03 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/33654092 Ethnic and trans-ethnic genome-wide association studies identify new loci influencing Japanese Alzheimer's disease risk. Alzheimer's disease 3,962 Japanese ancestry cases, 4,074 Japanese ancestry controls 1,216 Japanese ancestry cases, 2,446 Japanese ancestry controls Affymetrix [4852957] (imputed) 3 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST012215 Genome-wide genotyping array 8036 2021-08-20 33654092 Shigemizu D 2021-03-03 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/33654092 Ethnic and trans-ethnic genome-wide association studies identify new loci influencing Japanese Alzheimer's disease risk. Alzheimer's disease 3,962 Japanese ancestry cases, 4,074 Japanese ancestry controls, 21,982 European ancestry cases, 41,944 European ancestry controls 1,216 Japanese ancestry cases, 2,446 Japanese ancestry controls Affymetrix [2067592] (imputed) 8 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST012214 Genome-wide genotyping array 71962 2021-08-13 33649051 Duchen D 2021-03-01 Infect Immun www.ncbi.nlm.nih.gov/pubmed/33649051 Host genome wide association study of infant susceptibility to Shigella-associated diarrhea. Shigella-associated diarrhea 143 Bangladeshi cases, 446 Bangladeshi controls NA Illumina [5729117] (imputed) 12 shigellosis http://www.ebi.ac.uk/efo/EFO_0005585 GCST012207 Genome-wide genotyping array 589 2021-08-18 33657282 Liu X 2021-03-03 Aging Cell www.ncbi.nlm.nih.gov/pubmed/33657282 Integrated genetic analyses revealed novel human longevity loci and reduced risks of multiple diseases in a cohort study of 15,651 Chinese individuals. Longevity 11,045 Chinese ancestry individuals NA Affymetrix, Illumina [NR] (imputed) 10 longevity http://www.ebi.ac.uk/efo/EFO_0004300 GCST012210 Genome-wide genotyping array 11045 2018-07-05 29559738 Sasayama D 2018-03-20 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/29559738 A genome-wide association study on photic sneeze syndrome in a Japanese population. Photic sneeze reflex 360 Japanese ancestry cases, 11,049 Japanese ancestry controls NA Illumina [210086] 3 autosomal dominant compelling helio-ophthalmic outburst syndrome http://www.ebi.ac.uk/efo/EFO_0007887 GCST005809 Genome-wide genotyping array 11409 2018-05-30 29566793 Nicolas A 2018-03-21 Neuron www.ncbi.nlm.nih.gov/pubmed/29566793 Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. Amyotrophic lateral sclerosis 20,806 European ancestry cases, 59,804 European ancestry controls 4,159 cases, 18,650 controls Illumina [10031630] (imputed) 10 amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0000253 GCST005647 Genome-wide genotyping array 80610 2021-04-12 33485957 Patrick MT 2021-01-21 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/33485957 Associations between COVID-19 and skin conditions identified through epidemiology and genomic studies. COVID-19 or psoriasis (trans-disease meta-analysis) 1,678 COVID-19 cases, 11,024 psoriasis cases, 690,971 controls NA NR [NR] 1 psoriasis, COVID-19 http://www.ebi.ac.uk/efo/EFO_0000676, http://purl.obolibrary.org/obo/MONDO_0100096 GCST011477 Genome-wide genotyping array 703692 2021-04-12 33485957 Patrick MT 2021-01-21 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/33485957 Associations between COVID-19 and skin conditions identified through epidemiology and genomic studies. COVID-19 or atopic dermatitis (trans-disease meta-analysis) 30,937 COVID-19 cases, 21,000 atopic dermatitis cases, 1,566,815 controls NA NR [NR] 1 atopic eczema, COVID-19 http://www.ebi.ac.uk/efo/EFO_0000274, http://purl.obolibrary.org/obo/MONDO_0100096 GCST011476 Genome-wide genotyping array 1618771 2021-03-22 33491310 Warner ET 2021-02-01 Obesity (Silver Spring) www.ncbi.nlm.nih.gov/pubmed/33491310 A Genome-Wide Association Study of Childhood Body Fatness. Childhood body fatness 34,401 European ancestry individuals NA Affymetrix, Illumina [10031233] (imputed) 14 fat body mass http://www.ebi.ac.uk/efo/EFO_0005409 GCST011370 Genome-wide genotyping array 34401 2021-08-13 33574088 Mocci E 2021-02-11 Cancer Res www.ncbi.nlm.nih.gov/pubmed/33574088 Smoking modifies pancreatic cancer risk loci on 2q21.3. Pancreatic ductal adenocarcinoma x smoking interaction 7,937 European ancestry cases, 11,774 European ancestry controls NA Illumina [6769447] (imputed) 4 smoking status measurement, pancreatic carcinoma http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0002618 GCST012178 Genome-wide genotyping array 19711 2021-08-13 33560138 Dube MP 2021-02-09 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/33560138 Pharmacogenomics of the Efficacy and Safety of Colchicine in COLCOT. Cardiovascular event in colchicine-treated recent myocardial infarction (time to event) 39 European ancestry cases, 663 European ancestry controls NA Illumina [4462492] (imputed) 1 cardiovascular event measurement http://www.ebi.ac.uk/efo/EFO_0006919 GCST012188 Genome-wide genotyping array 702 2021-08-13 33560138 Dube MP 2021-02-09 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/33560138 Pharmacogenomics of the Efficacy and Safety of Colchicine in COLCOT. Cardiovascular event in colchicine-treated recent myocardial infarction (time to event) 30 European ancestry male cases, 546 European ancestry male controls NA Illumina [4455743] (imputed) 1 cardiovascular event measurement http://www.ebi.ac.uk/efo/EFO_0006919 GCST012187 Genome-wide genotyping array 576 2021-08-13 33560138 Dube MP 2021-02-09 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/33560138 Pharmacogenomics of the Efficacy and Safety of Colchicine in COLCOT. Gastrointestinal event in colchicine-treated recent myocardial infarction (time to event) 187 European ancestry cases, 580 European ancestry controls NA Illumina [4468817] (imputed) 2 Abdominal symptom http://purl.obolibrary.org/obo/HP_0011458 GCST012186 Genome-wide genotyping array 767 2021-08-13 33560138 Dube MP 2021-02-09 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/33560138 Pharmacogenomics of the Efficacy and Safety of Colchicine in COLCOT. Gastrointestinal event in colchicine-treated recent myocardial infarction (time to event) 622 European ancestry men NA Illumina [4468817] (imputed) 0 Abdominal symptom http://purl.obolibrary.org/obo/HP_0011458 GCST012185 Genome-wide genotyping array 622 2020-06-24 32424353 Zhang H 2020-05-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32424353 Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses. Breast cancer 133,384 European ancestry cases, 113,789 European ancestry controls NA Illumina [~ 10800000] (imputed) 29 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST010098 Genome-wide genotyping array 247173 2020-06-24 32424353 Zhang H 2020-05-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32424353 Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses. Invasive breast cancer 106,278 European ancestry cases, 91,477 European ancestry controls NA Illumina [~ 9700000] (imputed) 22 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST010099 Genome-wide genotyping array 197755 2020-06-24 32424353 Zhang H 2020-05-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/32424353 Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses. Breast cancer (estrogen-receptor negative, progesterone-receptor negative, and human epidermal growth factor-receptor negative) 8,602 European ancestry triple negative cases, 9,414 European ancestry BRCA1 mutation carrier cases, 100,971 European ancestry controls NA Illumina [~ 9700000] (imputed) 3 triple-negative breast cancer http://www.ebi.ac.uk/efo/EFO_0005537 GCST010100 Genome-wide genotyping array 118988 2021-05-21 32918390 Lin GY 2020-09-12 Ann Clin Transl Neurol www.ncbi.nlm.nih.gov/pubmed/32918390 Association of genetic variants in migraineurs with and without restless legs syndrome. Restless legs syndrome in migraine without aura 27 Taiwanese ancestry cases, 142 Taiwanese ancestry controls NA Affymetrix [710525] 5 restless legs syndrome http://www.ebi.ac.uk/efo/EFO_0004270 GCST011712 Genome-wide genotyping array 169 2021-05-21 32918390 Lin GY 2020-09-12 Ann Clin Transl Neurol www.ncbi.nlm.nih.gov/pubmed/32918390 Association of genetic variants in migraineurs with and without restless legs syndrome. Restless legs syndrome in migraine with aura 26 Taiwanese ancestry cases, 34 Taiwanese ancestry controls NA Affymetrix [710525] 0 restless legs syndrome http://www.ebi.ac.uk/efo/EFO_0004270 GCST011711 Genome-wide genotyping array 60 2021-05-21 32918390 Lin GY 2020-09-12 Ann Clin Transl Neurol www.ncbi.nlm.nih.gov/pubmed/32918390 Association of genetic variants in migraineurs with and without restless legs syndrome. Restless legs syndrome in migraine 53 Taiwanese ancestry cases, 180 Taiwanese ancestry controls NA Affymetrix [710525] 2 restless legs syndrome http://www.ebi.ac.uk/efo/EFO_0004270 GCST011710 Genome-wide genotyping array 233 2019-02-13 30153862 Maxwell TJ 2018-08-28 Alzheimers Res Ther www.ncbi.nlm.nih.gov/pubmed/30153862 Genome-wide association study for variants that modulate relationships between cerebrospinal fluid amyloid-beta 42, tau, and p-tau levels. Cerebrospinal fluid t-tau:AB1-42 ratio 3,146 European ancestry individuals NA Illumina [5088365] (imputed) 5 t-tau:beta-amyloid 1-42 ratio measurement http://www.ebi.ac.uk/efo/EFO_0007708 GCST007130 Genome-wide genotyping array 3146 2019-02-13 30153862 Maxwell TJ 2018-08-28 Alzheimers Res Ther www.ncbi.nlm.nih.gov/pubmed/30153862 Genome-wide association study for variants that modulate relationships between cerebrospinal fluid amyloid-beta 42, tau, and p-tau levels. Cerebrospinal fluid t-tau:AB1-42 ratio 3,146 European ancestry individuals NA Illumina [5088365] (imputed) 3 t-tau:beta-amyloid 1-42 ratio measurement http://www.ebi.ac.uk/efo/EFO_0007708 GCST007129 Genome-wide genotyping array 3146 2020-08-26 32438682 Mateos MK 2020-05-19 Cancers (Basel) www.ncbi.nlm.nih.gov/pubmed/32438682 Genome-Wide Association Meta-Analysis of Single-Nucleotide Polymorphisms and Symptomatic Venous Thromboembolism during Therapy for Acute Lymphoblastic Leukemia and Lymphoma in Caucasian Children. Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism 92 European ancestry cases, 1,481 European ancestry controls NA Illumina [NR] (imputed) 26 venous thromboembolism, response to antineoplastic agent http://www.ebi.ac.uk/efo/EFO_0004286, http://purl.obolibrary.org/obo/GO_0097327 GCST010463 Genome-wide genotyping array 1573 2020-08-27 32445792 Bani-Fatemi A 2020-05-20 Neurosci Lett www.ncbi.nlm.nih.gov/pubmed/32445792 Genome-wide association study of aggression and violence in schizophrenia. Physical aggression in schizophrenia 205 individuals NA Illumina [NR] 1 aggressive behavior http://www.ebi.ac.uk/efo/EFO_0003015 GCST010467 Genome-wide genotyping array 205 2020-08-27 32445792 Bani-Fatemi A 2020-05-20 Neurosci Lett www.ncbi.nlm.nih.gov/pubmed/32445792 Genome-wide association study of aggression and violence in schizophrenia. Verbal aggression in schizophrenia 205 individuals NA Illumina [NR] 2 aggressive behavior http://www.ebi.ac.uk/efo/EFO_0003015 GCST010466 Genome-wide genotyping array 205 2020-08-27 32445792 Bani-Fatemi A 2020-05-20 Neurosci Lett www.ncbi.nlm.nih.gov/pubmed/32445792 Genome-wide association study of aggression and violence in schizophrenia. Aggression against property in schizophrenia 205 individuals NA Illumina [NR] 0 aggressive behavior http://www.ebi.ac.uk/efo/EFO_0003015 GCST010465 Genome-wide genotyping array 205 2020-09-21 32518416 Dawoud AAZ 2020-06-10 Leukemia www.ncbi.nlm.nih.gov/pubmed/32518416 Clonal myelopoiesis in the UK Biobank cohort: ASXL1 mutations are strongly associated with smoking. Myeloid clonal hematopoiesis 1,166 cases, 30,892 controls NA Affymetrix [265112] 7 clonal hematopoiesis http://www.ebi.ac.uk/efo/EFO_0010819 GCST010596 Genome-wide genotyping array 32058 2021-07-01 33037222 Sieh W 2020-10-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33037222 Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk. Mammographic density (dense area) 24,192 European ancestry individuals NA Affymetrix [9906178] (imputed) 19 mammographic density measurement http://www.ebi.ac.uk/efo/EFO_0005941 GCST90011731 Genome-wide genotyping array 24192 2021-07-01 33037222 Sieh W 2020-10-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33037222 Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk. Mammographic density (non-dense area) 24,192 European ancestry individuals NA Affymetrix [9906178] (imputed) 15 mammographic density measurement http://www.ebi.ac.uk/efo/EFO_0005941 GCST90011732 Genome-wide genotyping array 24192 2021-07-01 33037222 Sieh W 2020-10-09 Nat Commun www.ncbi.nlm.nih.gov/pubmed/33037222 Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk. Percent mammographic density 24,192 European ancestry individuals NA Affymetrix [9906178] (imputed) 22 mammographic density percentage http://www.ebi.ac.uk/efo/EFO_0006502 GCST90011733 Genome-wide genotyping array 24192 2020-09-10 32514006 Cho SK 2020-06-08 Sci Rep www.ncbi.nlm.nih.gov/pubmed/32514006 Polygenic analysis of the effect of common and low-frequency genetic variants on serum uric acid levels in Korean individuals. Serum uric acid levels 6,881 Korean ancestry individuals 3,914 Korean ancestry individuals Affymetrix, Illumina [6129701] (imputed) 34 uric acid measurement http://www.ebi.ac.uk/efo/EFO_0004761 GCST010512 Genome-wide genotyping array 6881 2020-09-07 32433338 St Jean PL 2020-05-19 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/32433338 Pharmacogenetic assessment of tafenoquine efficacy in patients with Plasmodium vivax malaria. Tafenoquine efficacy in P. vivax malaria (recurrence by 6 months) 438 cases NA Affymetrix [10600000] (imputed) 1 disease recurrence, response to tafenoquine http://www.ebi.ac.uk/efo/EFO_0004952, http://www.ebi.ac.uk/efo/EFO_0010808 GCST010503 Genome-wide genotyping array 438 2020-09-07 32433338 St Jean PL 2020-05-19 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/32433338 Pharmacogenetic assessment of tafenoquine efficacy in patients with Plasmodium vivax malaria. Tafenoquine efficacy in P. vivax malaria (recurrence by 4 months) 438 cases NA Affymetrix [10600000] (imputed) 1 disease recurrence, response to tafenoquine http://www.ebi.ac.uk/efo/EFO_0004952, http://www.ebi.ac.uk/efo/EFO_0010808 GCST010502 Genome-wide genotyping array 438 2020-09-07 32433338 St Jean PL 2020-05-19 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/32433338 Pharmacogenetic assessment of tafenoquine efficacy in patients with Plasmodium vivax malaria. Tafenoquine efficacy in P. vivax malaria (time to recurrence up to 6 months) 438 cases NA Affymetrix [10600000] (imputed) 0 disease recurrence, response to tafenoquine http://www.ebi.ac.uk/efo/EFO_0004952, http://www.ebi.ac.uk/efo/EFO_0010808 GCST010501 Genome-wide genotyping array 438 2020-06-22 23727859 Ellinghaus D 2013-06-02 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23727859 High-density genotyping study identifies four new susceptibility loci for atopic dermatitis. Atopic dermatitis 2,425 European ancestry cases, 5,449 European ancestry controls 1,951 European ancestry cases, 4,599 European ancestry controls Illumina [128830] 9 atopic eczema http://www.ebi.ac.uk/efo/EFO_0000274 GCST010090 Targeted genotyping array [ImmunoChip] 7874 2020-10-13 32558222 Okamura K 2020-06-18 Pigment Cell Melanoma Res www.ncbi.nlm.nih.gov/pubmed/32558222 Genome-wide association study identifies CDH13 as a susceptibility gene for rhododendrol-induced leukoderma. Leukoderma in response to rhododendrol 147 Japanese ancestry cases, 112 Japanese ancestry controls NA Illumina [1057565] 10 Vitiligo, response to rhododendrol http://www.ebi.ac.uk/efo/EFO_0004208, http://www.ebi.ac.uk/efo/EFO_0010824 GCST010676 Genome-wide genotyping array 259 2020-09-21 32516399 Lin C 2020-06-09 Chem Senses www.ncbi.nlm.nih.gov/pubmed/32516399 Studies of human twins reveal genetic variation that affects dietary fat perception. Dietary fat liking 331 European ancestry individuals, 50 African ancestry individuals, 19 individuals NA Illumina [4234798] (imputed) 10 dietary fat liking measurement http://www.ebi.ac.uk/efo/EFO_0010816 GCST010600 Genome-wide genotyping array 400 2020-09-21 32516399 Lin C 2020-06-09 Chem Senses www.ncbi.nlm.nih.gov/pubmed/32516399 Studies of human twins reveal genetic variation that affects dietary fat perception. Dietary fat liking 331 European ancestry individuals, 50 African ancestry individuals, 19 individuals NA Illumina [4234798] (imputed) 13 dietary fat liking measurement http://www.ebi.ac.uk/efo/EFO_0010816 GCST010599 Genome-wide genotyping array 400 2020-11-02 32517579 Armstrong NJ 2020-06-10 Stroke www.ncbi.nlm.nih.gov/pubmed/32517579 Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities. Deep white matter hyperintensities 16,832 European ancestry individuals, 736 African American individuals, 658 Hispanic individuals 8,428 European and unknown ancestry individuals Affymetrix, Illumina [NR] (imputed) 45 white matter hyperintensity measurement http://www.ebi.ac.uk/efo/EFO_0005665 GCST010727 Genome-wide genotyping array 18226 2020-11-02 32517579 Armstrong NJ 2020-06-10 Stroke www.ncbi.nlm.nih.gov/pubmed/32517579 Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities. Periventricular white matter hyperintensities 16,832 European ancestry individuals, 736 African American individuals, 658 Hispanic individuals 8,428 European and unknown ancestry individuals Affymetrix, Illumina [NR] (imputed) 82 white matter hyperintensity measurement http://www.ebi.ac.uk/efo/EFO_0005665 GCST010726 Genome-wide genotyping array 18226 2020-11-06 32562552 Chua KC 2020-06-20 Clin Pharmacol Ther www.ncbi.nlm.nih.gov/pubmed/32562552 Genome-Wide Meta-Analysis Validates a Roless for S1PR1 in Microtubule Targeting Agent-Induced Sensory Peripheral Neuropathy. Sensory peripheral neuropathy in microtubule targeting agent-treated breast cancer 1,324 European ancestry individuals NA Illumina [6030476] (imputed) 18 peripheral neuropathy, response to antimicrotubule agent http://www.ebi.ac.uk/efo/EFO_0003100, http://www.ebi.ac.uk/efo/EFO_0005260 GCST010732 Genome-wide genotyping array 1324 2020-09-14 32556615 Liu Y 2020-06-18 Diabetologia www.ncbi.nlm.nih.gov/pubmed/32556615 Metabolomic and genetic associations with insulin resistance in pregnancy. Gestational insulin sensitivity 1,126 Afro-Caribbean individuals, 1,380 European ancestry individuals, 830 Mexican-American individuals, 1,192 Thai ancestry individuals NA Illumina [6168240] (imputed) 1 insulin sensitivity measurement http://www.ebi.ac.uk/efo/EFO_0004471 GCST010558 Genome-wide genotyping array 4528 2021-06-14 32538071 Chen Y 2020-06-15 Chem Res Toxicol www.ncbi.nlm.nih.gov/pubmed/32538071 Metabolism and toxicity of emodin: Genome-wide association studies reveal hepatocyte nuclear factor 4α regulates UGT2B7 and emodin glucuronidation. emodin-3-G formation rate 36 individuals NA Illumina [687188] 0 emodin glucuronidation measurement http://www.ebi.ac.uk/efo/EFO_0600010 GCST011857 Genome-wide genotyping array 36 2020-12-11 33020668 Koyama S 2020-10-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33020668 Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease. Coronary artery disease 25,892 Japanese ancestry cases, 142,336 Japanese ancestry controls NA Illumina [19707525] (imputed) 73 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST010867 Genome-wide genotyping array 168228 2020-12-11 33020668 Koyama S 2020-10-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33020668 Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease. Coronary artery disease 25,892 Japanese ancestry cases, 95,342 European ancestry cases, 142,336 Japanese ancestry controls, 385,488 European ancestry controls NA Illumina [4804024] (imputed) 175 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST010866 Genome-wide genotyping array 649058 2021-01-27 32534018 Liu X 2020-06-10 Brain Behav Immun www.ncbi.nlm.nih.gov/pubmed/32534018 Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders - findings from a Danish population-based study. Autoimmune traits 1,383 Danish ancestry cases, 62,656 Danish ancestry controls NA NR [7721839] (imputed) 12 autoimmune disease http://www.ebi.ac.uk/efo/EFO_0005140 GCST011008 Genome-wide genotyping array 64039 2021-01-27 32534018 Liu X 2020-06-10 Brain Behav Immun www.ncbi.nlm.nih.gov/pubmed/32534018 Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders - findings from a Danish population-based study. Mental disorder 43,902 Danish ancestry cases, 19,790 Danish ancestry controls NA NR [7721839] (imputed) 0 mental or behavioural disorder http://www.ebi.ac.uk/efo/EFO_0000677 GCST011006 Genome-wide genotyping array 63692 2021-01-27 32534018 Liu X 2020-06-10 Brain Behav Immun www.ncbi.nlm.nih.gov/pubmed/32534018 Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders - findings from a Danish population-based study. Autoimmune disease (without mental disorder) 347 Danish ancestry cases, 62,656 Danish ancestry controls NA NR [7721839] (imputed) 0 autoimmune disease http://www.ebi.ac.uk/efo/EFO_0005140 GCST011005 Genome-wide genotyping array 63003 2021-01-27 32534018 Liu X 2020-06-10 Brain Behav Immun www.ncbi.nlm.nih.gov/pubmed/32534018 Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders - findings from a Danish population-based study. Mental disorder (without autoimmune disease) 42,866 Danish ancestry cases, 19,790 Danish ancestry controls NA NR [7721839] (imputed) 3 mental or behavioural disorder http://www.ebi.ac.uk/efo/EFO_0000677 GCST011007 Genome-wide genotyping array 62656 2021-01-27 32534018 Liu X 2020-06-10 Brain Behav Immun www.ncbi.nlm.nih.gov/pubmed/32534018 Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders - findings from a Danish population-based study. Autoimmune disease and mental disorder 1,036 Danish ancestry cases, 19,790 Danish ancestry controls NA NR [7721839] (imputed) 1 mental or behavioural disorder, autoimmune disease http://www.ebi.ac.uk/efo/EFO_0000677, http://www.ebi.ac.uk/efo/EFO_0005140 GCST011009 Genome-wide genotyping array 20826 2021-05-10 32554045 Rao S 2020-06-15 Gene www.ncbi.nlm.nih.gov/pubmed/32554045 Genome-wide copy number variation-, validation- and screening study implicates a new copy number polymorphism associated with suicide attempts in major depressive disorder. Suicide attempts in major depressive disorder 43 Chinese ancestry cases, 43 Chinese ancestry controls 74 Chinese ancestry cases, 127 Chinese ancestry controls Illumina [745680] 0 attempted suicide http://www.ebi.ac.uk/efo/EFO_0004321 GCST011636 Genome-wide genotyping array 86 2021-02-03 32603185 Ibi D 2020-06-30 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/32603185 Genome-wide Association Study of the Postprandial Triglyceride Response Yields Common Genetic Variation in Hepatic Lipase (LIPC). Fasting triglyceride levels 5,630 individuals NA Illumina [NR] (imputed) 5 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST011052 Genome-wide genotyping array 5630 2021-02-03 32603185 Ibi D 2020-06-30 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/32603185 Genome-wide Association Study of the Postprandial Triglyceride Response Yields Common Genetic Variation in Hepatic Lipase (LIPC). Postprandial triglyceride levels 5,630 individuals NA Illumina [NR] (imputed) 6 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST011051 Genome-wide genotyping array 5630 2021-02-03 32603185 Ibi D 2020-06-30 Circ Genom Precis Med www.ncbi.nlm.nih.gov/pubmed/32603185 Genome-wide Association Study of the Postprandial Triglyceride Response Yields Common Genetic Variation in Hepatic Lipase (LIPC). Postprandial triglyceride response 5,630 individuals NA Illumina [NR] (imputed) 7 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST011050 Genome-wide genotyping array 5630 2020-09-15 32555152 Smith RL 2020-06-19 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32555152 Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients-a genome-wide association study adjusting for smoking habits. Clozapine concentration in schizophrenia 3,473 European ancestry individuals NA Illumina [up to 6200000] (imputed) 1 NA NA GCST010565 Genome-wide genotyping array 3473 2020-09-15 32555152 Smith RL 2020-06-19 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32555152 Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients-a genome-wide association study adjusting for smoking habits. N-desmethylclozapine concentration in schizophrenia 3,473 European ancestry individuals NA Illumina [up to 6200000] (imputed) 2 NA NA GCST010564 Genome-wide genotyping array 3473 2020-09-15 32555152 Smith RL 2020-06-19 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/32555152 Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients-a genome-wide association study adjusting for smoking habits. Clozapine-to-N-desmethylclozapine metabolic ratio in schizophrenia 3,473 European ancestry individuals NA Illumina [up to 6200000] (imputed) 2 NA NA GCST010563 Genome-wide genotyping array 3473 2020-09-21 32546850 Campos AI 2020-06-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/32546850 Genetic aetiology of self-harm ideation and behaviour. Deliberate self-harm 6,872 European ancestry cases, 150,008 European ancestry controls NA Affymetrix [NR] (imputed) 1 Self-injurious behavior http://purl.obolibrary.org/obo/HP_0100716 GCST010603 Genome-wide genotyping array 156880 2020-09-21 32546850 Campos AI 2020-06-16 Sci Rep www.ncbi.nlm.nih.gov/pubmed/32546850 Genetic aetiology of self-harm ideation and behaviour. Self-harm ideation 23,192 European ancestry cases, 133,524 European ancestry controls NA Affymetrix [NR] (imputed) 1 self-injurious ideation http://www.ebi.ac.uk/efo/EFO_0010817 GCST010602 Genome-wide genotyping array 156716 2021-02-03 32619740 Makarawate P 2020-06-30 Heart Rhythm www.ncbi.nlm.nih.gov/pubmed/32619740 Common and rare susceptibility genetic variants predisposing to Brugada Syndrome in Thailand. Brugada syndrome 154 Thai cases, 432 Thai controls NA Illumina [5310833] (imputed) 3 Brugada syndrome http://www.orpha.net/ORDO/Orphanet_130 GCST011054 Genome-wide genotyping array 586 2021-01-26 32603359 Ferreira MAR 2020-06-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/32603359 Age-of-onset information helps identify 76 genetic variants associated with allergic disease. Allergic disease (asthma, hay fever and/or eczema) (age of onset) 117,130 European ancestry individuals NA NR [7647814] (imputed) 53 allergy, age at onset http://www.ebi.ac.uk/efo/EFO_0003785, http://www.ebi.ac.uk/efo/EFO_0004847 GCST010985 Genome-wide genotyping array 117130 2021-01-26 32603359 Ferreira MAR 2020-06-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/32603359 Age-of-onset information helps identify 76 genetic variants associated with allergic disease. Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) 477,968 European ancestry individuals NA NR [NR] (imputed) 52 allergy http://www.ebi.ac.uk/efo/EFO_0003785 GCST010984 Genome-wide genotyping array 477968 2021-02-03 32733355 Ryu HS 2020-07-07 Front Neurol www.ncbi.nlm.nih.gov/pubmed/32733355 Genomic Analysis Identifies New Loci Associated With Motor Complications in Parkinson's Disease. Motor fluctuations in levodopa treated Parkinson's disease 219 Korean ancestry cases, 522 Korean ancestry controls NA Affymetrix [583535] (imputed) 4 motor function measurement, response to levodopa http://www.ebi.ac.uk/efo/EFO_0010749, http://www.ebi.ac.uk/efo/EFO_0010747 GCST011066 Genome-wide genotyping array 741 2021-02-03 32733355 Ryu HS 2020-07-07 Front Neurol www.ncbi.nlm.nih.gov/pubmed/32733355 Genomic Analysis Identifies New Loci Associated With Motor Complications in Parkinson's Disease. Levodopa-induced dyskinesia in levodopa treated Parkinson's disease 172 Korean ancestry cases, 569 Korean ancestry controls NA Affymetrix [583535] (imputed) 12 drug-Induced dyskinesia, response to levodopa http://www.ebi.ac.uk/efo/EFO_1000904, http://www.ebi.ac.uk/efo/EFO_0010747 GCST011065 Genome-wide genotyping array 741 2021-05-24 32653958 Cho HW 2020-07-11 J Bone Miner Metab www.ncbi.nlm.nih.gov/pubmed/32653958 Association between non-Caucasian-specific ASCC1 gene polymorphism and osteoporosis and obesity in Korean postmenopausal women. Body mass index 3,013 Korean ancestry individuals NA Affymetrix [NR] 3 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST011717 Genome-wide genotyping array 3013 2021-05-24 32653958 Cho HW 2020-07-11 J Bone Miner Metab www.ncbi.nlm.nih.gov/pubmed/32653958 Association between non-Caucasian-specific ASCC1 gene polymorphism and osteoporosis and obesity in Korean postmenopausal women. Osteoporosis 443 Korean ancestry cases, 2,223 Korean ancestry controls NA Affymetrix [NR] 5 osteoporosis http://www.ebi.ac.uk/efo/EFO_0003882 GCST011716 Genome-wide genotyping array 2666 2021-05-27 32726798 Hong X 2020-07-29 Pediatr Res www.ncbi.nlm.nih.gov/pubmed/32726798 Genome-wide association study identifies a novel maternal gene × stress interaction associated with spontaneous preterm birth. spontaneous preterm birth x maternal stress interaction (1df) 457 African American cases, 1,033 African American controls 171 African American cases, 166 African American controls, 353 European ancestry cases, 385 European ancestry controls Illumina [at least 2160368] (imputed) 1 psychosocial stress measurement, spontaneous preterm birth http://www.ebi.ac.uk/efo/EFO_0006783, http://www.ebi.ac.uk/efo/EFO_0006917 GCST011740 Genome-wide genotyping array 1490 2021-06-08 32491161 Chu BB 2020-06-01 Gigascience www.ncbi.nlm.nih.gov/pubmed/32491161 Iterative hard thresholding in genome-wide association studies: Generalized linear models, prior weights, and double sparsity. Hypertension 185,565 European ancestry individuals NA NR [470228] 0 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST011824 Genome-wide genotyping array 185565 2021-06-08 32491161 Chu BB 2020-06-01 Gigascience www.ncbi.nlm.nih.gov/pubmed/32491161 Iterative hard thresholding in genome-wide association studies: Generalized linear models, prior weights, and double sparsity. High density lipoprotein cholesterol levels 5,402 individuals NA NR [364590] 0 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST011825 Genome-wide genotyping array 5402 2020-08-26 32671202 Du M 2020-05-20 Sci Adv www.ncbi.nlm.nih.gov/pubmed/32671202 Remote modulation of lncRNA GCLET by risk variant at 16p13 underlying genetic susceptibility to gastric cancer. Gastric cancer 1,625 Chinese ancestry cases, 2,100 Chinese ancestry controls 5,353 Chinese ancestry cases, 6,685 Chinese ancestry controls, 254 European ancestry cases, 2,835 European ancestry controls NR [4817140] (imputed) 2 gastric carcinoma http://www.ebi.ac.uk/efo/EFO_0000178 GCST010462 Genome-wide genotyping array 3725 2021-05-14 32719713 Zhang F 2020-07-03 Front Genet www.ncbi.nlm.nih.gov/pubmed/32719713 Independent Replication on Genome-Wide Association Study Signals Identifies IRF3 as a Novel Locus for Systemic Lupus Erythematosus. Systemic lupus erythematosus 4,943 European ancestry cases, 2,485 Asian ancestry cases, 8,483 European ancestry controls, 3,947 Asian ancestry controls 2,269 Han Chinese ancestry cases, 5,073 Han Chinese ancestry controls NR [NR] (imputed) 0 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST011661 Genome-wide genotyping array 19858 2021-03-24 32724131 Li QS 2020-07-28 Sci Rep www.ncbi.nlm.nih.gov/pubmed/32724131 Genome-wide association study and polygenic risk score analysis of esketamine treatment response. Response to esketamine in treatment resistant depression 255 European ancestry individuals NA NR [NR] (imputed) 40 response to ketamine http://www.ebi.ac.uk/efo/EFO_0009748 GCST011398 Genome-wide genotyping array 255 2021-03-24 32724131 Li QS 2020-07-28 Sci Rep www.ncbi.nlm.nih.gov/pubmed/32724131 Genome-wide association study and polygenic risk score analysis of esketamine treatment response. Response to esketamine (responder status) in treatment resistant depression 255 European ancestry individuals NA NR [NR] (imputed) 11 response to ketamine http://www.ebi.ac.uk/efo/EFO_0009748 GCST011397 Genome-wide genotyping array 255 2021-03-24 32724131 Li QS 2020-07-28 Sci Rep www.ncbi.nlm.nih.gov/pubmed/32724131 Genome-wide association study and polygenic risk score analysis of esketamine treatment response. Response to esketamine (remission) in treatment resistant depression 255 European ancestry remitters, 272 European ancestry non-remitters NA NR [NR] (imputed) 5 response to ketamine http://www.ebi.ac.uk/efo/EFO_0009748 GCST011396 Genome-wide genotyping array 527 2020-07-22 32650023 Gabryszewski SJ 2020-07-07 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/32650023 Unsupervised Modeling and Genome-Wide Association Identify Novel Features of Allergic March Trajectories. Allergic march (atopic dermatitis to allergic rhinitis) 225 African American child cases, 963 African American child controls 148 African American child cases, 1,151 African American child controls Illumina [52127467] (imputed) 1 atopic march http://www.ebi.ac.uk/efo/EFO_0007755 GCST90000019 Genome-wide genotyping array 1188 2020-07-22 32650023 Gabryszewski SJ 2020-07-07 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/32650023 Unsupervised Modeling and Genome-Wide Association Identify Novel Features of Allergic March Trajectories. Allergic march (atopic dermatitis to asthma) 335 African American child cases, 963 African American child controls 220 African American child cases, 1,151 African American child controls Illumina [52106158] (imputed) 1 atopic march http://www.ebi.ac.uk/efo/EFO_0007755 GCST90000020 Genome-wide genotyping array 1298 2020-07-22 32650023 Gabryszewski SJ 2020-07-07 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/32650023 Unsupervised Modeling and Genome-Wide Association Identify Novel Features of Allergic March Trajectories. Allergic march (atopic dermatitis to allergic rhinitis) 115 African American child male cases, 466 African American child male controls 74 African American child male cases, 543 African American child male controls Illumina [52184427] (imputed) 1 atopic march http://www.ebi.ac.uk/efo/EFO_0007755 GCST90000021 Genome-wide genotyping array 581 2020-07-22 32650023 Gabryszewski SJ 2020-07-07 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/32650023 Unsupervised Modeling and Genome-Wide Association Identify Novel Features of Allergic March Trajectories. Allergic march (atopic dermatitis to asthma) 198 African American child male cases, 466 African American child male controls 127 African American child male cases, 543 African American child male controls Illumina [52169262] (imputed) 0 atopic march http://www.ebi.ac.uk/efo/EFO_0007755 GCST90000022 Genome-wide genotyping array 664 2020-07-22 32650023 Gabryszewski SJ 2020-07-07 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/32650023 Unsupervised Modeling and Genome-Wide Association Identify Novel Features of Allergic March Trajectories. Allergic march (atopic dermatitis to allergic rhinitis) 110 African American child female cases, 496 African American child female controls 74 African American child female cases, 606 African American child female controls Illumina [52122499] (imputed) 1 atopic march http://www.ebi.ac.uk/efo/EFO_0007755 GCST90000023 Genome-wide genotyping array 606 2020-07-22 32650023 Gabryszewski SJ 2020-07-07 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/32650023 Unsupervised Modeling and Genome-Wide Association Identify Novel Features of Allergic March Trajectories. Allergic march (atopic dermatitis to asthma) 137 African American child female cases, 496 African American child female controls 92 African American child female cases, 606 African American child female controls Illumina [52090676] (imputed) 0 atopic march http://www.ebi.ac.uk/efo/EFO_0007755 GCST90000024 Genome-wide genotyping array 633 2019-09-12 31383772 Yan C 2019-08-05 Gut www.ncbi.nlm.nih.gov/pubmed/31383772 Meta-analysis of genome-wide association studies and functional assays decipher susceptibility genes for gastric cancer in Chinese populations. Gastric cancer 3,771 Chinese ancestry cases, 5,426 Chinese ancestry controls 7,035 Chinese ancestry cases, 8,323 Chinese ancestry controls Affymetrix, Illumina [6192596] (imputed) 6 gastric carcinoma http://www.ebi.ac.uk/efo/EFO_0000178 GCST008646 Genome-wide genotyping array 9197 2019-04-09 30767168 Shin JH 2019-02-14 Genes Genomics www.ncbi.nlm.nih.gov/pubmed/30767168 Genetic risk score combining six genetic variants associated with the cellular NRF2 expression levels correlates with Type 2 diabetes in the human population. Cellular nuclear factor (erythroid-derived 2)-like 2 levels 74 East Asian ancestry lymphoblastoid cell lines NA Affymetrix [352228] (imputed) 6 NRF2 measurement http://www.ebi.ac.uk/efo/EFO_0009794 GCST007538 Genome-wide genotyping array 74 2019-03-11 30760885 Mbarek H 2019-02-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/30760885 Biological insights into multiple birth: genetic findings from UK Biobank. Number of twin births 8,962 European ancestry cases, 409,591 European ancestry controls NA Affymetrix [8532721] (imputed) 2 multiple births measurement http://www.ebi.ac.uk/efo/EFO_0009439 GCST007280 Genome-wide genotyping array 418553 2018-12-03 30348214 Zhang Q 2018-10-22 Genome Med www.ncbi.nlm.nih.gov/pubmed/30348214 Genotype effects contribute to variation in longitudinal methylome patterns in older people. DNA methylation variation (age effect) Up to 954 individuals NA Illumina [7760689] (imputed) 436 DNA methylation http://purl.obolibrary.org/obo/GO_0006306 GCST006660 Genome-wide genotyping array 954 2019-08-05 31120506 Grassmann F 2019-05-23 JAMA Ophthalmol www.ncbi.nlm.nih.gov/pubmed/31120506 Assessment of Novel Genome-Wide Significant Gene Loci and Lesion Growth in Geographic Atrophy Secondary to Age-Related Macular Degeneration. Geographic atrophy lesion growth rate in age-related macular degeneration 935 European ancestry individuals NA Affymetrix [7596219] (imputed) 3 geographic atrophy lesion growth http://www.ebi.ac.uk/efo/EFO_0010080 GCST008356 Genome-wide genotyping array 935 2019-03-18 30514930 Mukherjee S 2018-12-04 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30514930 Genetic data and cognitively defined late-onset Alzheimer's disease subgroups. Alzheimer's disease with memory domain impairment Up to 1,107 European ancestry cases, 3,447 European ancestry controls NA NR [up to 6398204] (imputed) 2 Alzheimer's disease, memory impairment http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0001072 GCST007330 Genome-wide genotyping array 4554 2019-03-18 30514930 Mukherjee S 2018-12-04 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30514930 Genetic data and cognitively defined late-onset Alzheimer's disease subgroups. Alzheimer's disease with language domain impairment Up to 510 European ancestry cases, 3,447 European ancestry controls NA NR [up to 6398204] (imputed) 6 Alzheimer's disease, language impairment http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0005425 GCST007334 Genome-wide genotyping array 3957 2019-03-17 30514930 Mukherjee S 2018-12-04 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30514930 Genetic data and cognitively defined late-onset Alzheimer's disease subgroups. Alzheimer's disease with visuospatial domain impairment Up to 497 European ancestry cases, 3,447 European ancestry controls NA NR [up to 6398204] (imputed) 9 Alzheimer's disease, visuospatial impairment http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0009752 GCST007318 Genome-wide genotyping array 3944 2019-03-18 30514930 Mukherjee S 2018-12-04 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30514930 Genetic data and cognitively defined late-onset Alzheimer's disease subgroups. Alzheimer's disease with multiple cognitive domain impairments Up to 248 European ancestry cases, 3,447 European ancestry controls NA NR [up to 6398204] (imputed) 9 Alzheimer's disease, Cognitive impairment http://www.ebi.ac.uk/efo/EFO_0000249, http://purl.obolibrary.org/obo/HP_0100543 GCST007332 Genome-wide genotyping array 3695 2019-03-18 30514930 Mukherjee S 2018-12-04 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30514930 Genetic data and cognitively defined late-onset Alzheimer's disease subgroups. Alzheimer's disease with no specific cognitive domain impairment Up to 1,584 European ancestry cases, 3,447 European ancestry controls NA NR [up to 6398204] (imputed) 7 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST007333 Genome-wide genotyping array 5031 2019-03-18 30514930 Mukherjee S 2018-12-04 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/30514930 Genetic data and cognitively defined late-onset Alzheimer's disease subgroups. Alzheimer's disease 2,431 European ancestry cases, 3,447 European ancestry controls NA NR [up to 6398204] (imputed) 0 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST007331 Genome-wide genotyping array 5878 2019-03-28 30510157 Franceschini N 2018-12-03 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30510157 GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Carotid intima media thickness Up to 71,128 European ancestry individuals NA Affymetrix, Illumina [9574088] (imputed) 13 common carotid intimal medial thickness http://www.ebi.ac.uk/efo/EFO_0004860 GCST007436 Genome-wide genotyping array 71128 2019-03-28 30510157 Franceschini N 2018-12-03 Nat Commun www.ncbi.nlm.nih.gov/pubmed/30510157 GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Carotid plaque Up to 21,540 European ancestry cases, up to 26,894 European ancestry controls NA Affymetrix, Illumina [8578107] (imputed) 7 carotid atherosclerosis http://www.ebi.ac.uk/efo/EFO_0009783 GCST007435 Genome-wide genotyping array 48434 2019-08-28 31250787 Fawns-Ritchie C 2019-06-01 Twin Res Hum Genet www.ncbi.nlm.nih.gov/pubmed/31250787 Genetic Contributions to Health Literacy. Health literacy 1,771 English ancestry cases, 4,012 English ancestry controls NA Illumina [NR] (imputed) 38 health literacy measurement http://www.ebi.ac.uk/efo/EFO_0010104 GCST008513 Genome-wide genotyping array 5783 2019-08-15 31243853 Chung S 2019-06-27 J Viral Hepat www.ncbi.nlm.nih.gov/pubmed/31243853 GWAS identifying HLA-DPB1 gene variants associated with responsiveness to hepatitis B virus vaccination in Koreans: Independent association of HLA-DPB1*04:02 possessing rs1042169 G - rs9277355 C - rs9277356 A. Response to hepatitis B vaccine 1,760 Korean ancestry non-responder adults, 5,107 Korean ancestry responder adults 2,327 Korean ancestry adults, 49 Korean ancestry non-responder infants, 234 Korean ancestry responder infants Affymetrix [345072] 1 Anti-hepatitis B virus surface antigen IgG measurement, response to vaccine http://www.ebi.ac.uk/efo/EFO_0009358, http://www.ebi.ac.uk/efo/EFO_0004645 GCST008435 Genome-wide genotyping array 6867 2020-04-17 31958309 Hsieh AR 2020-01-01 BMJ Open Diabetes Res Care www.ncbi.nlm.nih.gov/pubmed/31958309 Lack of association of genetic variants for diabetic retinopathy in Taiwanese patients with diabetic nephropathy. Diabetic retinopathy in type 2 diabetes 206 East Asian ancestry cases, 206 East Asian ancestry controls NA Affymetrix, Illumina [NR] (imputed) 3 diabetic retinopathy http://www.ebi.ac.uk/efo/EFO_0003770 GCST009840 Genome-wide genotyping array 412 2021-04-30 32592749 Butler-Laporte G 2020-06-24 Clin Microbiol Infect www.ncbi.nlm.nih.gov/pubmed/32592749 Elevated body-mass index is associated with an increased risk of infectious disease admissions and mortality: a mendelian randomization study. Sepsis (hospital admission) 4,403 European ancestry cases, 17,612 European ancestry controls NA NR [NR] 3 Sepsis http://purl.obolibrary.org/obo/HP_0100806 GCST011598 Genome-wide genotyping array 22015 2021-04-30 32592749 Butler-Laporte G 2020-06-24 Clin Microbiol Infect www.ncbi.nlm.nih.gov/pubmed/32592749 Elevated body-mass index is associated with an increased risk of infectious disease admissions and mortality: a mendelian randomization study. Pneumonia (28-day mortality) 513 European ancestry cases, 6,685 European ancestry controls NA NR [NR] 1 pneumonia, mortality http://www.ebi.ac.uk/efo/EFO_0003106, http://www.ebi.ac.uk/efo/EFO_0004352 GCST011597 Genome-wide genotyping array 7198 2021-04-30 32592749 Butler-Laporte G 2020-06-24 Clin Microbiol Infect www.ncbi.nlm.nih.gov/pubmed/32592749 Elevated body-mass index is associated with an increased risk of infectious disease admissions and mortality: a mendelian randomization study. Pneumonia (90-day mortality) 738 European ancestry cases, 6,460 European ancestry controls NA NR [NR] 1 pneumonia, mortality http://www.ebi.ac.uk/efo/EFO_0003106, http://www.ebi.ac.uk/efo/EFO_0004352 GCST011596 Genome-wide genotyping array 7198 2021-04-30 32592749 Butler-Laporte G 2020-06-24 Clin Microbiol Infect www.ncbi.nlm.nih.gov/pubmed/32592749 Elevated body-mass index is associated with an increased risk of infectious disease admissions and mortality: a mendelian randomization study. Sepsis (28-day mortality) 210 European ancestry cases, 1,827 European ancestry controls NA NR [NR] 7 Sepsis, mortality http://purl.obolibrary.org/obo/HP_0100806, http://www.ebi.ac.uk/efo/EFO_0004352 GCST011595 Genome-wide genotyping array 2037 2021-04-30 32592749 Butler-Laporte G 2020-06-24 Clin Microbiol Infect www.ncbi.nlm.nih.gov/pubmed/32592749 Elevated body-mass index is associated with an increased risk of infectious disease admissions and mortality: a mendelian randomization study. Sepsis (90-day mortality) 341 European ancestry cases, 1,696 European ancestry controls NA NR [NR] 1 Sepsis, mortality http://purl.obolibrary.org/obo/HP_0100806, http://www.ebi.ac.uk/efo/EFO_0004352 GCST011594 Genome-wide genotyping array 2037 2021-04-30 32592749 Butler-Laporte G 2020-06-24 Clin Microbiol Infect www.ncbi.nlm.nih.gov/pubmed/32592749 Elevated body-mass index is associated with an increased risk of infectious disease admissions and mortality: a mendelian randomization study. Infectious disease (hospital admission) 31,455 European ancestry cases, 125,820 European ancestry controls NA NR [NR] 0 infectious disease http://www.ebi.ac.uk/efo/EFO_0005741 GCST011593 Genome-wide genotyping array 157275 2021-04-30 32592749 Butler-Laporte G 2020-06-24 Clin Microbiol Infect www.ncbi.nlm.nih.gov/pubmed/32592749 Elevated body-mass index is associated with an increased risk of infectious disease admissions and mortality: a mendelian randomization study. Pneumonia (hospital admission) 10,472 European ancestry cases, 41,888 European ancestry controls NA NR [NR] 0 pneumonia http://www.ebi.ac.uk/efo/EFO_0003106 GCST011592 Genome-wide genotyping array 52360 2021-04-30 32592749 Butler-Laporte G 2020-06-24 Clin Microbiol Infect www.ncbi.nlm.nih.gov/pubmed/32592749 Elevated body-mass index is associated with an increased risk of infectious disease admissions and mortality: a mendelian randomization study. Skin and soft tissue infections (hospital admission) 10,858 European ancestry cases, 43,432 European ancestry controls NA NR [NR] 0 infectious disease http://www.ebi.ac.uk/efo/EFO_0005741 GCST011591 Genome-wide genotyping array 54290 2021-04-30 32592749 Butler-Laporte G 2020-06-24 Clin Microbiol Infect www.ncbi.nlm.nih.gov/pubmed/32592749 Elevated body-mass index is associated with an increased risk of infectious disease admissions and mortality: a mendelian randomization study. Urinary tract infection (hospital admission) 13,307 European ancestry cases, 53,228 European ancestry controls NA NR [NR] 0 urinary tract infection http://www.ebi.ac.uk/efo/EFO_0003103 GCST011590 Genome-wide genotyping array 66535 2021-09-06 33852427 Wittekind DA 2021-04-01 Eur J Endocrinol www.ncbi.nlm.nih.gov/pubmed/33852427 Genome-wide association and transcriptome analysis suggests total serum ghrelin to be linked with GFRAL. ghrelin levels 1,501 individuals NA Affymetrix [9868623] (imputed) 13 ghrelin measurement http://www.ebi.ac.uk/efo/EFO_0600001 GCST012316 Genome-wide genotyping array 1501 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 1) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012880 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 27) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012906 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 28) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012907 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 29) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012908 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 7) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012886 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 31) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012910 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 10) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012889 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 11) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012890 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 12) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012891 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 34) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012913 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 15) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012894 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 16) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012895 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 17) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012896 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 18) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012897 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 19) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012898 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 20) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012899 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 21) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012900 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 40) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012919 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 24) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012903 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 42) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012921 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 43) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012922 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 44) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012923 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 45) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012924 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 46) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012925 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 47) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012926 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 48) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012927 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 49) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012928 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 50) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012929 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 101) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012980 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 102) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012981 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 103) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012982 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 104) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012983 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 105) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012984 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 106) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012985 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 107) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012986 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 108) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012987 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 109) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012988 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 110) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012989 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 111) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012990 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 112) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012991 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 113) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012992 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 114) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012993 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 115) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012994 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 116) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012995 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 117) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012996 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 118) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012997 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 119) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012998 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 120) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012999 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 121) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013000 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 122) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013001 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 123) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013002 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 124) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013003 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 125) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013004 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 176) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013055 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 177) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013056 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 178) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013057 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 179) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013058 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 180) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013059 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 181) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013060 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 182) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013061 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 183) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013062 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 184) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013063 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 185) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013064 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 186) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013065 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 187) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013066 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 188) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013067 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 189) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013068 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 190) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013069 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 191) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013070 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 192) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013071 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 193) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013072 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 194) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013073 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 195) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013074 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 196) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013075 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 197) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013076 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 198) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013077 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 199) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013078 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 200) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013079 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 126) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013005 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 127) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013006 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 128) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013007 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 129) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013008 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 130) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013009 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 131) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013010 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 132) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013011 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 133) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013012 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 134) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013013 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 135) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013014 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 136) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013015 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 137) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013016 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 138) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013017 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 139) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013018 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 140) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013019 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 141) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013020 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 142) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013021 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 143) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013022 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 144) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013023 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 145) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013024 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 146) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013025 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 147) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013026 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 148) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013027 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 149) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013028 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 150) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013029 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 76) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012955 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 77) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012956 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 78) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012957 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 79) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012958 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 80) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012959 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 81) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012960 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 82) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012961 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 83) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012962 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 84) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012963 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 85) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012964 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 86) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012965 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 87) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012966 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 88) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012967 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 89) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012968 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 90) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012969 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 91) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012970 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 92) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012971 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 93) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012972 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 94) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012973 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 95) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012974 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 96) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012975 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 97) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012976 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 98) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012977 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 99) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012978 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 100) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012979 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 151) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013030 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 152) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013031 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 153) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013032 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 154) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013033 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 155) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013034 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 156) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013035 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 157) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013036 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 158) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013037 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 159) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013038 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 160) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013039 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 161) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013040 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 162) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013041 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 163) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013042 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 164) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013043 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 165) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013044 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 166) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013045 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 167) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013046 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 168) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013047 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 169) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013048 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 170) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013049 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 171) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013050 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 172) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013051 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 173) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013052 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 174) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013053 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 175) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013054 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 51) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012930 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 52) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012931 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 53) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012932 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 54) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012933 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 55) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012934 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 56) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012935 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 57) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012936 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 58) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012937 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 59) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012938 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 60) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012939 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 61) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012940 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 62) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012941 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 63) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012942 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 64) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012943 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 65) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012944 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 66) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012945 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 67) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012946 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 68) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012947 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 69) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012948 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 70) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012949 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 71) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012950 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 72) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012951 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 73) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012952 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 74) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012953 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 75) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012954 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 26) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012905 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 2) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012881 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 3) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012882 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 4) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012883 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 5) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012884 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 6) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012885 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 30) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012909 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 8) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012887 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 9) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012888 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 32) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012911 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 33) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012912 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 13) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012892 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 14) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012893 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 35) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012914 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 36) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012915 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 37) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012916 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 38) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012917 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 39) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012918 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 22) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012901 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 23) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012902 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 41) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012920 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 25) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90012904 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 226) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013105 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 227) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013106 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 228) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013107 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 229) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013108 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 230) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013109 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 231) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013110 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 232) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013111 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 233) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013112 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 234) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013113 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 235) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013114 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 236) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013115 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 237) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013116 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 238) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013117 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 239) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013118 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 240) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013119 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 241) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013120 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 242) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013121 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 243) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013122 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 244) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013123 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 245) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013124 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 246) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013125 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 247) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013126 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 248) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013127 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 249) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013128 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 250) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013129 Genome-wide genotyping array 19670 2021-06-17 33227023 Wang Y 2020-11-23 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33227023 Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth. C-reactive protein levels 8,318 European ancestry individuals NA Illumina [~ 9000000] (imputed) 2 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST011919 Genome-wide genotyping array 8318 2021-06-17 33227023 Wang Y 2020-11-23 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33227023 Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth. Erythropoietin levels 8,318 European ancestry individuals NA Illumina [~ 9000000] (imputed) 1 erythropoetin measurement http://www.ebi.ac.uk/efo/EFO_0008391 GCST011918 Genome-wide genotyping array 8318 2021-06-17 33227023 Wang Y 2020-11-23 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33227023 Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth. IgA levels 8,318 European ancestry individuals NA Illumina [~ 9000000] (imputed) 1 serum IgA measurement http://www.ebi.ac.uk/efo/EFO_0004912 GCST011917 Genome-wide genotyping array 8318 2021-06-17 33227023 Wang Y 2020-11-23 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33227023 Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth. Interleukin-18 levels 8,318 European ancestry individuals (see Ahola-Olli 2017) Illumina [~ 9000000] (imputed) 4 interleukin 18 measurement http://www.ebi.ac.uk/efo/EFO_0004581 GCST011916 Genome-wide genotyping array 8318 2021-06-17 33227023 Wang Y 2020-11-23 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33227023 Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth. Monocyte chemoattractant protein-1 levels 8,318 European ancestry individuals (see Ahola-Olli 2017) Illumina [~ 9000000] (imputed) 10 CCL2 measurement http://www.ebi.ac.uk/efo/EFO_0004749 GCST011915 Genome-wide genotyping array 8318 2021-06-17 33227023 Wang Y 2020-11-23 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33227023 Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth. S100 calcium-binding protein levels 8,318 European ancestry individuals 1,141 European ancestry individuals Illumina [~ 9000000] (imputed) 1 S100 calcium-binding protein B measurement http://www.ebi.ac.uk/efo/EFO_0600012 GCST011914 Genome-wide genotyping array 8318 2021-06-17 33227023 Wang Y 2020-11-23 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33227023 Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth. Thymus and reactivation regulated chemokine levels 8,318 European ancestry individuals NA Illumina [~ 9000000] (imputed) 4 CCL17 measurement http://www.ebi.ac.uk/efo/EFO_0009414 GCST011913 Genome-wide genotyping array 8318 2021-06-17 33227023 Wang Y 2020-11-23 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33227023 Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth. Vascular endothelial growth factor A levels 8,318 European ancestry individuals (see Ahola-Olli 2017) Illumina [~ 9000000] (imputed) 5 vascular endothelial growth factor A measurement http://www.ebi.ac.uk/efo/EFO_0010804 GCST011912 Genome-wide genotyping array 8318 2021-06-17 33227023 Wang Y 2020-11-23 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33227023 Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth. Brain-derived neurotrophic factor levels 8,318 European ancestry individuals 1,141 European ancestry individuals Illumina [~ 9000000] (imputed) 0 NA NA GCST011911 Genome-wide genotyping array 8318 2021-06-17 33227023 Wang Y 2020-11-23 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33227023 Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth. Interleukin-8 levels 8,318 European ancestry individuals 1,141 European ancestry individuals Illumina [~ 9000000] (imputed) 0 interleukin-8 measurement http://www.ebi.ac.uk/efo/EFO_0004811 GCST011910 Genome-wide genotyping array 8318 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 201) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013080 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 202) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013081 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 203) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013082 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 204) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013083 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 205) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013084 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 206) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013085 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 207) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013086 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 208) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013087 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 209) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013088 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 210) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013089 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 211) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013090 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 212) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013091 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 213) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013092 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 214) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013093 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 215) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013094 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 216) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013095 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 217) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013096 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 218) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013097 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 219) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013098 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 220) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013099 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 221) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013100 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 222) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013101 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 223) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013102 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 224) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013103 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 225) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013104 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 251) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013130 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 252) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013131 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 253) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013132 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 254) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013133 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 255) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013134 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 256) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013135 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 257) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013136 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 258) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013137 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 259) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013138 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 260) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013139 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 261) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013140 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 262) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013141 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 263) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013142 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 264) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013143 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 265) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013144 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 266) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013145 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 267) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013146 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 268) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013147 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 269) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013148 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 270) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013149 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 271) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013150 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 272) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013151 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 273) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013152 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 274) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013153 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 275) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013154 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 276) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013155 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 277) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013156 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 278) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013157 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 279) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013158 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 280) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013159 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 281) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013160 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 282) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013161 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 283) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013162 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 284) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013163 Genome-wide genotyping array 19670 2021-04-27 33821002 Naqvi S 2021-04-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33821002 Shared heritability of human face and brain shape. Brain shape (segment 285) 19,670 European ancestry individuals NA NR [9705931] (imputed) 0 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST90013164 Genome-wide genotyping array 19670 2021-09-27 33875642 Duran-Lozano L 2021-04-19 Blood Cancer J www.ncbi.nlm.nih.gov/pubmed/33875642 Germline variants at SOHLH2 influence multiple myeloma risk. Multiple myeloma or monoclonal gammopathy of undetermined significance 4,376 European ancestry multiple myeloma cases, 944 European ancestry monoclonal gammopathy of undetermined significance cases, 422,293 European ancestry controls NA Illumina [33000000] (imputed) 1 multiple myeloma, monoclonal gammopathy http://www.ebi.ac.uk/efo/EFO_0001378, http://www.ebi.ac.uk/efo/EFO_0000203 GCST012397 Genome-wide genotyping array 427613 2021-09-27 33875642 Duran-Lozano L 2021-04-19 Blood Cancer J www.ncbi.nlm.nih.gov/pubmed/33875642 Germline variants at SOHLH2 influence multiple myeloma risk. Multiple myeloma 4,376 European ancestry cases, 345,887 European ancestry controls 5,598 European ancestry cases, 15,261 European ancestry controls Illumina [33000000] (imputed) 13 multiple myeloma http://www.ebi.ac.uk/efo/EFO_0001378 GCST012396 Genome-wide genotyping array 350263 2020-12-08 32915782 Spracklen CN 2020-09-11 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/32915782 Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences. Adiponectin levels (BMI-adjusted) 9,262 European ancestry individuals NA Illumina [16607452] (imputed) 12 BMI-adjusted adiponectin measurement http://www.ebi.ac.uk/efo/EFO_0007737 GCST90011881 Genome-wide genotyping array 9262 2020-12-08 32915782 Spracklen CN 2020-09-11 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/32915782 Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences. Adiponectin levels (fat percentage adjusted) 9,262 European ancestry individuals NA Illumina [16607452] (imputed) 0 adiponectin measurement http://www.ebi.ac.uk/efo/EFO_0004502 GCST90011882 Genome-wide genotyping array 9262 2020-12-08 32915782 Spracklen CN 2020-09-11 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/32915782 Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences. Adiponectin levels (BMI-adjusted) 9,262 European ancestry individuals NA Illumina [39120605] (imputed) 0 BMI-adjusted adiponectin measurement http://www.ebi.ac.uk/efo/EFO_0007737 GCST90011883 Genome-wide genotyping array 9262 2021-09-09 33907183 Guo S 2021-04-27 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/33907183 Genome wide association study identifies four loci for early onset schizophrenia. Early-onset schizophrenia 1,256 Han Chinese ancestry cases, 2,661 Han Chinese ancestry controls 903 Han Chinese ancestry cases, 3,900 Han Chinese ancestry controls Illumina [4867007] (imputed) 15 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST012368 Genome-wide genotyping array 3917 2021-05-05 31511581 Joo J 2019-09-11 Sci Rep www.ncbi.nlm.nih.gov/pubmed/31511581 The association of integration patterns of human papilloma virus and single nucleotide polymorphisms on immune- or DNA repair-related genes in cervical cancer patients. Human papilloma virus infection in cervical cancer 161 Korean ancestry individuals with cervical cancer NA Affymetrix [166505] 0 human papilloma virus infection http://www.ebi.ac.uk/efo/EFO_0001668 GCST011620 Targeted genotyping array [custom array] 161 2021-05-12 31577861 Dai J 2019-10-31 Int J Cancer www.ncbi.nlm.nih.gov/pubmed/31577861 Genome-wide association study of INDELs identified four novel susceptibility loci associated with lung cancer risk. Lung cancer 20,871 European ancestry cases, 15,971 European ancestry controls, 2,331 Chinese ancestry cases, 3,077 Chinese ancestry controls NA Illumina [484196] 19 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST011656 Targeted genotyping array [Oncoarray] 42250 2021-06-08 33941792 Yoshimura K 2021-05-03 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33941792 A web-based survey on various symptoms of computer vision syndrome and the genetic understanding based on a multi-trait genome-wide association study. Computer vision syndrome 1,966 Japanese ancestry individuals NA Illumina [540916] (imputed) 10 vision disorder http://purl.obolibrary.org/obo/MONDO_0021084 GCST011826 Genome-wide genotyping array 1966 2021-06-03 33926923 Rahman MS 2021-04-29 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/33926923 Genome-wide association study identifies RNF123 locus as associated with chronic widespread musculoskeletal pain. Chronic widespread musculoskeletal pain 6,914 European ancestry cases, 242,929 European ancestry controls 14,177 European ancestry cases, 28,903 European ancestry controls Affymetrix [NR] (imputed) 0 chronic widespread pain http://www.ebi.ac.uk/efo/EFO_0010099 GCST011779 Genome-wide genotyping array 249843 2021-09-27 33939221 He X 2021-05-03 Hum Brain Mapp www.ncbi.nlm.nih.gov/pubmed/33939221 The morphometry of left cuneus mediating the genetic regulation on working memory. Left cuneus volume 753 European ancestry individuals, 301 individuals NA Illumina [11061864] (imputed) 0 brain volume measurement http://www.ebi.ac.uk/efo/EFO_0006930 GCST012404 Genome-wide genotyping array 1054 2021-06-11 33941608 Khan A 2021-05-03 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/33941608 Medical Records-Based Genetic Studies of the Complement System. Complement C3 levels 3,210 European ancestry individuals, 589 African ancestry individuals, 150 East Asian ancestry individuals NA NR [NR] (imputed) 4 complement C3 measurement http://www.ebi.ac.uk/efo/EFO_0004983 GCST011834 Genome-wide genotyping array 3949 2021-06-11 33941608 Khan A 2021-05-03 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/33941608 Medical Records-Based Genetic Studies of the Complement System. Complement C4 levels 3,247 European ancestry individuals, 600 African ancestry individuals, 151 East Asian ancestry individuals NA NR [NR] (imputed) 14 complement C4 measurement http://www.ebi.ac.uk/efo/EFO_0004984 GCST011833 Genome-wide genotyping array 3998 2021-07-27 33959940 Chen Y 2021-05-06 Br J Dermatol www.ncbi.nlm.nih.gov/pubmed/33959940 A GWAS identifies novel gene associations with facial skin wrinkling and mole count in Latin-Americans. Facial wrinkles (forehead) 6,254 Latin American individuals NA Illumina [8703729] (imputed) 4 Facial wrinkling http://purl.obolibrary.org/obo/HP_0009762 GCST012109 Genome-wide genotyping array 6254 2021-07-27 33959940 Chen Y 2021-05-06 Br J Dermatol www.ncbi.nlm.nih.gov/pubmed/33959940 A GWAS identifies novel gene associations with facial skin wrinkling and mole count in Latin-Americans. Facial wrinkles (frown lines) 6,254 Latin American individuals NA Illumina [8703729] (imputed) 1 Facial wrinkling http://purl.obolibrary.org/obo/HP_0009762 GCST012108 Genome-wide genotyping array 6254 2021-07-27 33959940 Chen Y 2021-05-06 Br J Dermatol www.ncbi.nlm.nih.gov/pubmed/33959940 A GWAS identifies novel gene associations with facial skin wrinkling and mole count in Latin-Americans. Facial wrinkles (crow's feet) 6,254 Latin American individuals NA Illumina [8703729] (imputed) 2 Facial wrinkling http://purl.obolibrary.org/obo/HP_0009762 GCST012107 Genome-wide genotyping array 6254 2021-07-27 33959940 Chen Y 2021-05-06 Br J Dermatol www.ncbi.nlm.nih.gov/pubmed/33959940 A GWAS identifies novel gene associations with facial skin wrinkling and mole count in Latin-Americans. Nevus count 6,254 Latin American individuals NA Illumina [8703729] (imputed) 2 nevus count http://www.ebi.ac.uk/efo/EFO_0004632 GCST012106 Genome-wide genotyping array 6254 2021-07-27 33959940 Chen Y 2021-05-06 Br J Dermatol www.ncbi.nlm.nih.gov/pubmed/33959940 A GWAS identifies novel gene associations with facial skin wrinkling and mole count in Latin-Americans. Facial wrinkles (principal components analysis) 6,254 Latin American individuals NA Illumina [8703729] (imputed) 2 Facial wrinkling http://purl.obolibrary.org/obo/HP_0009762 GCST012105 Genome-wide genotyping array 6254 2021-07-27 33959940 Chen Y 2021-05-06 Br J Dermatol www.ncbi.nlm.nih.gov/pubmed/33959940 A GWAS identifies novel gene associations with facial skin wrinkling and mole count in Latin-Americans. Facial wrinkles (under eye) 6,254 Latin American individuals NA Illumina [8703729] (imputed) 0 Facial wrinkling http://purl.obolibrary.org/obo/HP_0009762 GCST012104 Genome-wide genotyping array 6254 2021-06-08 33958783 Liu G 2021-05-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33958783 Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson's disease. Parkinson's disease progression (cognitive) 2,650 European and unknown ancestry individuals 1,171 individuals Illumina [11220132] (imputed) 10 disease progression measurement http://www.ebi.ac.uk/efo/EFO_0008336 GCST011823 Genome-wide genotyping array 2650 2021-06-08 33941849 Chang X 2021-05-03 Commun Biol www.ncbi.nlm.nih.gov/pubmed/33941849 Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population. Telomere length 20,177 Chinese ancestry individuals 5,356 Chinese ancestry individuals Illumina [up to 4756872] (imputed) 4 telomere length http://www.ebi.ac.uk/efo/EFO_0004505 GCST011828 Genome-wide genotyping array 20177 2020-07-28 32450446 Wang H 2020-04-29 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/32450446 Genome-wide interaction analysis of pathological hallmarks in Alzheimer's disease. Neuritic plaques (SNP x SNP interaction) 1,316 individuals NA Affymetrix, Illumina [279409] (imputed) 93 neuritic plaque measurement http://www.ebi.ac.uk/efo/EFO_0006798 GCST010342 Genome-wide genotyping array 1316 2020-07-28 32450446 Wang H 2020-04-29 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/32450446 Genome-wide interaction analysis of pathological hallmarks in Alzheimer's disease. Diffuse plaques (SNP x SNP interaction) 1,316 individuals NA Affymetrix, Illumina [279409] (imputed) 275 diffuse plaque measurement http://www.ebi.ac.uk/efo/EFO_0010699 GCST010341 Genome-wide genotyping array 1316 2020-07-28 32450446 Wang H 2020-04-29 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/32450446 Genome-wide interaction analysis of pathological hallmarks in Alzheimer's disease. Total PHF-tau (SNP x SNP interaction) 1,285 individuals NA Affymetrix, Illumina [279409] (imputed) 1584 PHF-tau measurement http://www.ebi.ac.uk/efo/EFO_0010750 GCST010340 Genome-wide genotyping array 1285 2020-07-28 32450446 Wang H 2020-04-29 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/32450446 Genome-wide interaction analysis of pathological hallmarks in Alzheimer's disease. Total amyloid (SNP x SNP interaction) 1,276 individuals NA Affymetrix, Illumina [279409] (imputed) 96 amyloid-beta measurement http://www.ebi.ac.uk/efo/EFO_0005194 GCST010339 Genome-wide genotyping array 1276 2020-07-28 32450446 Wang H 2020-04-29 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/32450446 Genome-wide interaction analysis of pathological hallmarks in Alzheimer's disease. Neurofibrillary tangles (SNP x SNP interaction) 1,316 individuals NA Affymetrix, Illumina [279409] (imputed) 766 neurofibrillary tangles measurement http://www.ebi.ac.uk/efo/EFO_0006797 GCST010343 Genome-wide genotyping array 1316 2021-09-27 33830181 Tideman JWL 2021-04-08 JAMA Ophthalmol www.ncbi.nlm.nih.gov/pubmed/33830181 Evaluation of Shared Genetic Susceptibility to High and Low Myopia and Hyperopia. Low myopia 11,197 European ancestry low myopic cases, 21,416 European ancestry emmetropia controls NA NR [13958389] (imputed) 66 Myopia http://purl.obolibrary.org/obo/HP_0000545 GCST012402 Genome-wide genotyping array 32613 2021-09-27 33830181 Tideman JWL 2021-04-08 JAMA Ophthalmol www.ncbi.nlm.nih.gov/pubmed/33830181 Evaluation of Shared Genetic Susceptibility to High and Low Myopia and Hyperopia. Hyperopia 10,828 European ancestry hyperopia cases, 21,416 European ancestry emmetropia controls NA NR [13958389] (imputed) 78 Hypermetropia http://purl.obolibrary.org/obo/HP_0000540 GCST012401 Genome-wide genotyping array 32244 2021-09-27 33830181 Tideman JWL 2021-04-08 JAMA Ophthalmol www.ncbi.nlm.nih.gov/pubmed/33830181 Evaluation of Shared Genetic Susceptibility to High and Low Myopia and Hyperopia. Low myopia vs hyperopia 11,197 European ancestry low myopia cases, 10,828 European ancestry hyperopia cases NA NR [13958389] (imputed) 145 Hypermetropia, Myopia http://purl.obolibrary.org/obo/HP_0000540, http://purl.obolibrary.org/obo/HP_0000545 GCST012400 Genome-wide genotyping array 22025 2021-09-27 33830181 Tideman JWL 2021-04-08 JAMA Ophthalmol www.ncbi.nlm.nih.gov/pubmed/33830181 Evaluation of Shared Genetic Susceptibility to High and Low Myopia and Hyperopia. High myopia 3,164 European ancestry high myopic cases, 21,416 European ancestry emmetropia controls NA NR [13958389] (imputed) 152 Myopia http://purl.obolibrary.org/obo/HP_0000545 GCST012403 Genome-wide genotyping array 24580 2021-09-06 33824429 Fjukstad KK 2021-04-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/33824429 Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study. HDL levels x SSRI levels interaction in schizophrenia or bipolar disorder 1,180 European ancestry individuals NA Illumina [NR] (imputed) 1 response to selective serotonin reuptake inhibitor, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0005658, http://www.ebi.ac.uk/efo/EFO_0004612 GCST012330 Genome-wide genotyping array 1180 2021-09-06 33824429 Fjukstad KK 2021-04-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/33824429 Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study. LDL levels x SSRI levels interaction in schizophrenia or bipolar disorder 1,180 European ancestry individuals NA Illumina [NR] (imputed) 1 low density lipoprotein cholesterol measurement, response to selective serotonin reuptake inhibitor http://www.ebi.ac.uk/efo/EFO_0004611, http://www.ebi.ac.uk/efo/EFO_0005658 GCST012329 Genome-wide genotyping array 1180 2021-09-06 33824429 Fjukstad KK 2021-04-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/33824429 Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study. Total cholesterol levels x SSRI levels interaction in schizophrenia or bipolar disorder 1,180 European ancestry individuals NA Illumina [NR] (imputed) 1 total cholesterol measurement, response to selective serotonin reuptake inhibitor http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0005658 GCST012328 Genome-wide genotyping array 1180 2021-09-06 33824429 Fjukstad KK 2021-04-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/33824429 Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study. Triglyceride levels x SSRI levels interaction in schizophrenia or bipolar disorder 1,180 European ancestry individuals NA Illumina [NR] (imputed) 0 triglyceride measurement, response to selective serotonin reuptake inhibitor http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0005658 GCST012327 Genome-wide genotyping array 1180 2021-09-06 33824429 Fjukstad KK 2021-04-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/33824429 Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study. BMI x SSRI defined daily dose interaction in schizophrenia or bipolar disorder 1,180 European ancestry individuals NA Illumina [NR] (imputed) 4 response to selective serotonin reuptake inhibitor, body mass index http://www.ebi.ac.uk/efo/EFO_0005658, http://www.ebi.ac.uk/efo/EFO_0004340 GCST012326 Genome-wide genotyping array 1180 2021-09-06 33824429 Fjukstad KK 2021-04-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/33824429 Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study. HDL levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder 1,180 European ancestry individuals NA Illumina [NR] (imputed) 3 response to selective serotonin reuptake inhibitor, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0005658, http://www.ebi.ac.uk/efo/EFO_0004612 GCST012325 Genome-wide genotyping array 1180 2021-09-06 33824429 Fjukstad KK 2021-04-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/33824429 Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study. LDL levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder 1,180 European ancestry individuals NA Illumina [NR] (imputed) 14 low density lipoprotein cholesterol measurement, response to selective serotonin reuptake inhibitor http://www.ebi.ac.uk/efo/EFO_0004611, http://www.ebi.ac.uk/efo/EFO_0005658 GCST012324 Genome-wide genotyping array 1180 2021-09-06 33824429 Fjukstad KK 2021-04-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/33824429 Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study. Total cholesterol levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder 1,180 European ancestry individuals NA Illumina [NR] (imputed) 3 total cholesterol measurement, response to selective serotonin reuptake inhibitor http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0005658 GCST012323 Genome-wide genotyping array 1180 2021-09-06 33824429 Fjukstad KK 2021-04-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/33824429 Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study. Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder 1,180 European ancestry individuals NA Illumina [NR] (imputed) 52 triglyceride measurement, response to selective serotonin reuptake inhibitor http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0005658 GCST012322 Genome-wide genotyping array 1180 2021-09-06 33824429 Fjukstad KK 2021-04-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/33824429 Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study. BMI x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder 181 European ancestry individuals NA Illumina [NR] (imputed) 0 response to escitalopram, response to citalopram, body mass index http://www.ebi.ac.uk/efo/EFO_0007871, http://www.ebi.ac.uk/efo/EFO_0006329, http://www.ebi.ac.uk/efo/EFO_0004340 GCST012321 Genome-wide genotyping array 181 2021-09-06 33824429 Fjukstad KK 2021-04-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/33824429 Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study. HDL levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder 181 European ancestry individuals NA Illumina [NR] (imputed) 2 response to escitalopram, response to citalopram, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0007871, http://www.ebi.ac.uk/efo/EFO_0006329, http://www.ebi.ac.uk/efo/EFO_0004612 GCST012320 Genome-wide genotyping array 181 2021-09-06 33824429 Fjukstad KK 2021-04-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/33824429 Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study. LDL levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder 181 European ancestry individuals NA Illumina [NR] (imputed) 18 low density lipoprotein cholesterol measurement, response to escitalopram, response to citalopram http://www.ebi.ac.uk/efo/EFO_0004611, http://www.ebi.ac.uk/efo/EFO_0007871, http://www.ebi.ac.uk/efo/EFO_0006329 GCST012319 Genome-wide genotyping array 181 2021-09-06 33824429 Fjukstad KK 2021-04-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/33824429 Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study. Total cholesterol levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder 181 European ancestry individuals NA Illumina [NR] (imputed) 5 total cholesterol measurement, response to escitalopram, response to citalopram http://www.ebi.ac.uk/efo/EFO_0004574, http://www.ebi.ac.uk/efo/EFO_0007871, http://www.ebi.ac.uk/efo/EFO_0006329 GCST012318 Genome-wide genotyping array 181 2021-09-06 33824429 Fjukstad KK 2021-04-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/33824429 Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study. Triglyceride levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder 181 European ancestry individuals NA Illumina [NR] (imputed) 16 triglyceride measurement, response to escitalopram, response to citalopram http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0007871, http://www.ebi.ac.uk/efo/EFO_0006329 GCST012317 Genome-wide genotyping array 181 2021-09-06 33824429 Fjukstad KK 2021-04-06 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/33824429 Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study. BMI x SSRI levels interaction in schizophrenia or bipolar disorder 1,180 European ancestry individuals NA Illumina [NR] (imputed) 2 response to selective serotonin reuptake inhibitor, body mass index http://www.ebi.ac.uk/efo/EFO_0005658, http://www.ebi.ac.uk/efo/EFO_0004340 GCST012331 Genome-wide genotyping array 1180 2021-04-19 33541459 Glanville KP 2021-02-05 BJPsych Open www.ncbi.nlm.nih.gov/pubmed/33541459 Multiple measures of depression to enhance validity of major depressive disorder in the UK Biobank. Endorsed measures of depression (four or five) 4,887 European ancestry cases, 232,552 European ancestry controls NA NR [9940918] (imputed) 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90014426 Genome-wide genotyping array 237439 2021-04-19 33541459 Glanville KP 2021-02-05 BJPsych Open www.ncbi.nlm.nih.gov/pubmed/33541459 Multiple measures of depression to enhance validity of major depressive disorder in the UK Biobank. Endorsed measures of depression (four or five) vs mental health questionnaire controls 4,887 European ancestry cases, 57,805 European ancestry controls NA NR [9940918] (imputed) 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90014427 Genome-wide genotyping array 62692 2021-04-19 33541459 Glanville KP 2021-02-05 BJPsych Open www.ncbi.nlm.nih.gov/pubmed/33541459 Multiple measures of depression to enhance validity of major depressive disorder in the UK Biobank. Lifetime depression (mental health questionnaire) 28,982 European ancestry cases, 232,552 European ancestry controls NA NR [9940918] (imputed) 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90014428 Genome-wide genotyping array 261534 2021-04-19 33541459 Glanville KP 2021-02-05 BJPsych Open www.ncbi.nlm.nih.gov/pubmed/33541459 Multiple measures of depression to enhance validity of major depressive disorder in the UK Biobank. Lifetime depression (mental health questionnaire) vs mental health questionnaire controls 28,982 European ancestry cases, 57,805 European ancestry controls NA NR [9940918] (imputed) 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90014429 Genome-wide genotyping array 86787 2021-04-19 33541459 Glanville KP 2021-02-05 BJPsych Open www.ncbi.nlm.nih.gov/pubmed/33541459 Multiple measures of depression to enhance validity of major depressive disorder in the UK Biobank. Endorsed measures of depression (one) 57,321 European ancestry cases, 232,552 European ancestry controls NA NR [9940918] (imputed) 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90014430 Genome-wide genotyping array 289873 2021-04-19 33541459 Glanville KP 2021-02-05 BJPsych Open www.ncbi.nlm.nih.gov/pubmed/33541459 Multiple measures of depression to enhance validity of major depressive disorder in the UK Biobank. Endorsed measures of depression (one) vs mental health questionnaire controls 57,321 European ancestry cases, 57,805 European ancestry controls NA NR [9940918] (imputed) 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90014431 Genome-wide genotyping array 115126 2021-04-19 33541459 Glanville KP 2021-02-05 BJPsych Open www.ncbi.nlm.nih.gov/pubmed/33541459 Multiple measures of depression to enhance validity of major depressive disorder in the UK Biobank. Endorsed measures of depression (three) 9,738 European ancestry cases, 232,552 European ancestry controls NA NR [9940918] (imputed) 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90014432 Genome-wide genotyping array 242290 2021-04-19 33541459 Glanville KP 2021-02-05 BJPsych Open www.ncbi.nlm.nih.gov/pubmed/33541459 Multiple measures of depression to enhance validity of major depressive disorder in the UK Biobank. Endorsed measures of depression (three) vs mental health questionnaire controls 9,738 European ancestry cases, 57,805 European ancestry controls NA NR [9940918] (imputed) 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90014433 Genome-wide genotyping array 67543 2021-04-19 33541459 Glanville KP 2021-02-05 BJPsych Open www.ncbi.nlm.nih.gov/pubmed/33541459 Multiple measures of depression to enhance validity of major depressive disorder in the UK Biobank. Endorsed measures of depression (two) 21,468 European ancestry cases, 232,552 European ancestry controls NA NR [9940918] (imputed) 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90014434 Genome-wide genotyping array 254020 2021-04-19 33541459 Glanville KP 2021-02-05 BJPsych Open www.ncbi.nlm.nih.gov/pubmed/33541459 Multiple measures of depression to enhance validity of major depressive disorder in the UK Biobank. Endorsed measures of depression (two) vs mental health questionnaire controls 21,468 European ancestry cases, 57,805 European ancestry controls NA NR [9940918] (imputed) 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90014435 Genome-wide genotyping array 79273 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 381; Facial segment 11; 3D morphology of the nose 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90015894 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 382; Facial segment 11; 3D morphology of the nose 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90015895 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 383; Facial segment 11; 3D morphology of the nose 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90015896 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 384; Facial segment 11; 3D morphology of the nose 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90015897 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 385; Facial segment 11; 3D morphology of the nose 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90015898 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 386; Facial segment 11; 3D morphology of the nose 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90015899 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 387; Facial segment 11; 3D morphology of the nose 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90015900 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 388; Facial segment 11; 3D morphology of the nose 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90015901 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 389; Facial segment 11; 3D morphology of the nose 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90015902 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 390; Facial segment 11; 3D morphology of the nose 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90015903 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 391; Facial segment 11; 3D morphology of the nose 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90015904 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 392; Facial segment 11; 3D morphology of the nose 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90015905 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 393; Facial segment 11; 3D morphology of the nose 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90015906 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 394; Facial segment 11; 3D morphology of the nose 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90015907 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 395; Facial segment 11; 3D morphology of the nose 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90015908 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 396; Facial segment 11; 3D morphology of the nose 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90015909 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 397; Facial segment 11; 3D morphology of the nose 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90015910 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 398; Facial segment 11; 3D morphology of the nose 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90015911 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 399; Facial segment 11; 3D morphology of the nose 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90015912 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 400; Facial segment 11; 3D morphology of the nose 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 nose morphology measurement http://www.ebi.ac.uk/efo/EFO_0007843 GCST90015913 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 401; Facial segment 12; 3D morphology of the cheeks 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 facial morphology measurement http://www.ebi.ac.uk/efo/EFO_0007841 GCST90015914 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 402; Facial segment 12; 3D morphology of the cheeks 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 facial morphology measurement http://www.ebi.ac.uk/efo/EFO_0007841 GCST90015915 Genome-wide genotyping array 8246 2021-05-26 33983923 Hoskens H 2021-05-13 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33983923 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies. Sib-shared facial trait 403; Facial segment 12; 3D morphology of the cheeks 8,246 European ancestry individuals NA Illumina [7417619] (imputed) 0 facial morphology measurement http://www.ebi.ac.uk/efo/EFO_0007841 GCST90015916 Genome-wide genotyping array 8246 2020-10-30 30369944 Balakrishnan P 2018-10-12 Front Genet www.ncbi.nlm.nih.gov/pubmed/30369944 Genetic Variants Related to Cardiometabolic Traits Are Associated to B Cell Function, Insulin Resistance, and Diabetes Among AmeriCan Indians: The Strong Heart Family Study. HOMA-B (corrected for HOMA-IR) 1,892 American Indian ancestry individuals NA Illumina [120975] (imputed) 28 HOMA-B http://www.ebi.ac.uk/efo/EFO_0004469 GCST010724 Targeted genotyping array [Cardio-MetaboChip] 1892 2021-04-30 33842983 Chung RH 2021-04-12 Diabetologia www.ncbi.nlm.nih.gov/pubmed/33842983 Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on fasting glucose. Fasting blood glucose 18,122 Han Chinese ancestry individuals 1,989 Han Chinese ancestry individuals Affymetrix [774398] (imputed) 18 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST011587 Genome-wide genotyping array 18122 2021-08-31 33841421 Li J 2021-03-25 Front Immunol www.ncbi.nlm.nih.gov/pubmed/33841421 Variants at the MHC Region Associate With Susceptibility to Clostridioides difficile Infection: A Genome-Wide Association Study Using Comprehensive Electronic Health Records. Clostridioides difficle infection 1,160 European ancestry cases, 14,144 European ancestry controls NA Illumina [64973696] (imputed) 26 clostridium difficile infection http://www.ebi.ac.uk/efo/EFO_0009130 GCST012277 Genome-wide genotyping array 15304 2021-08-31 33841421 Li J 2021-03-25 Front Immunol www.ncbi.nlm.nih.gov/pubmed/33841421 Variants at the MHC Region Associate With Susceptibility to Clostridioides difficile Infection: A Genome-Wide Association Study Using Comprehensive Electronic Health Records. Clostridioides difficle infection in antibiotics-users 587 European ancestry cases, 3,166 European ancestry controls NA Illumina [64973696] (imputed) 22 clostridium difficile infection http://www.ebi.ac.uk/efo/EFO_0009130 GCST012276 Genome-wide genotyping array 3753 2021-07-13 33232597 Kong SH 2020-11-24 Endocrinol Metab (Seoul) www.ncbi.nlm.nih.gov/pubmed/33232597 Identification of Novel Genetic Variants Related to Trabecular Bone Score in Community-Dwelling Older Adults. trabecular bone score 2,451 Korean ancestry individuals 2,733 Korean ancestry individuals Affymetrix [1418709] (imputed) 0 trabecular bone score http://www.ebi.ac.uk/efo/EFO_0600018 GCST012025 Genome-wide genotyping array 2451 2021-06-17 33760818 Francis M 2021-03-24 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33760818 Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci. HDL levels x fish oil supplementation interaction (2df) 67,544 European ancestry individuals 7,284 European ancestry individuals Affymetrix [7954107] (imputed) 5 fish oil supplement exposure measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0600007, http://www.ebi.ac.uk/efo/EFO_0004612 GCST011927 Genome-wide genotyping array 67544 2021-06-17 33760818 Francis M 2021-03-24 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33760818 Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci. Total cholesterol levels x fish oil supplementation interaction (2df) 73,962 European ancestry individuals 7,283 European ancestry individuals Affymetrix [7953515] (imputed) 2 fish oil supplement exposure measurement, total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0600007, http://www.ebi.ac.uk/efo/EFO_0004574 GCST011926 Genome-wide genotyping array 73962 2021-06-17 33760818 Francis M 2021-03-24 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33760818 Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci. HDL levels x fish oil supplementation interaction (1df) 67,544 European ancestry individuals 7,284 European ancestry individuals Affymetrix [7954107] (imputed) 1 fish oil supplement exposure measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0600007, http://www.ebi.ac.uk/efo/EFO_0004612 GCST011930 Genome-wide genotyping array 67544 2021-06-17 33760818 Francis M 2021-03-24 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33760818 Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci. Total cholesterol levels x fish oil supplementation interaction (1df) 73,962 European ancestry individuals 7,283 European ancestry individuals Affymetrix [7953515] (imputed) 1 fish oil supplement exposure measurement, total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0600007, http://www.ebi.ac.uk/efo/EFO_0004574 GCST011929 Genome-wide genotyping array 73962 2021-06-17 33760818 Francis M 2021-03-24 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33760818 Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci. Triglyceride levels x fish oil supplementation interaction (1df) 73,908 European ancestry individuals 7,284 European ancestry individuals Affymetrix [7953600] (imputed) 2 fish oil supplement exposure measurement, triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0600007, http://www.ebi.ac.uk/efo/EFO_0004530 GCST011928 Genome-wide genotyping array 73908 2021-06-17 33760818 Francis M 2021-03-24 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33760818 Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci. LDL levels x fish oil supplementation interaction (1df) 73,832 European ancestry individuals 7,180 European ancestry individuals Affymetrix [7953137] (imputed) 2 fish oil supplement exposure measurement, low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0600007, http://www.ebi.ac.uk/efo/EFO_0004611 GCST011931 Genome-wide genotyping array 73832 2021-06-17 33760818 Francis M 2021-03-24 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33760818 Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci. Triglyceride levels x fish oil supplementation interaction (2df) 73,908 European ancestry individuals 7,284 European ancestry individuals Affymetrix [7953600] (imputed) 5 fish oil supplement exposure measurement, triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0600007, http://www.ebi.ac.uk/efo/EFO_0004530 GCST011925 Genome-wide genotyping array 73908 2021-06-17 33760818 Francis M 2021-03-24 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/33760818 Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci. LDL levels x fish oil supplementation interaction (2df) 73,832 European ancestry individuals 7,180 European ancestry individuals Affymetrix [7953137] (imputed) 4 fish oil supplement exposure measurement, low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0600007, http://www.ebi.ac.uk/efo/EFO_0004611 GCST011924 Genome-wide genotyping array 73832 2021-05-19 33074286 Kunkle BW 2020-10-19 JAMA Neurol www.ncbi.nlm.nih.gov/pubmed/33074286 Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis. Alzheimer's disease 2,784 African American cases, 5,222 African American controls NA Illumina [29610185] (imputed) 15 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST011696 Genome-wide genotyping array 8006 2021-06-17 33242228 Niu Y 2020-11-26 J Cell Mol Med www.ncbi.nlm.nih.gov/pubmed/33242228 Genome-wide association study identifies 7q11.22 and 7q36.3 associated with noise-induced hearing loss among Chinese population. Hearing loss in noise exposure 89 Chinese ancestry cases, 209 Chinese ancestry controls 53 Chinese ancestry cases, 360 Chinese ancestry controls Illumina [3830431] (imputed) 2 noise-induced hearing loss http://www.ebi.ac.uk/efo/EFO_1001254 GCST011920 Genome-wide genotyping array 298 2021-09-09 33891562 Hao Q 2021-04-23 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/33891562 Age-related differences of genetic susceptibility to patients with acute lymphoblastic leukemia. Acute lymphoblastic leukemia 466 Chinese ancestry cases, 1,466 Chinese ancestry controls NR NR [9466286] (imputed) 1 acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000220 GCST012357 Genome-wide genotyping array 1932 2021-09-09 33891562 Hao Q 2021-04-23 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/33891562 Age-related differences of genetic susceptibility to patients with acute lymphoblastic leukemia. Acute lymphoblastic leukemia (childhood) 381 Chinese ancestry cases, 1,466 Chinese ancestry controls NR NR [9466286] (imputed) 1 childhood acute lymphoblastic leukemia http://purl.obolibrary.org/obo/MONDO_0000870 GCST012360 Genome-wide genotyping array 1847 2021-09-09 33891562 Hao Q 2021-04-23 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/33891562 Age-related differences of genetic susceptibility to patients with acute lymphoblastic leukemia. Acute lymphoblastic leukemia (adult) 85 Chinese ancestry cases, 1,466 Chinese ancestry controls NR NR [9466286] (imputed) 1 acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000220 GCST012359 Genome-wide genotyping array 1551 2021-09-09 33891562 Hao Q 2021-04-23 Aging (Albany NY) www.ncbi.nlm.nih.gov/pubmed/33891562 Age-related differences of genetic susceptibility to patients with acute lymphoblastic leukemia. Acute lymphoblastic leukemia (adult vs childhood) 85 Chinese ancestry adult cases, 381 Chinese ancestry childhood cases NR NR [9466286] (imputed) 1 acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000220 GCST012358 Genome-wide genotyping array 466 2021-05-18 33884653 Li C 2021-04-21 Mov Disord www.ncbi.nlm.nih.gov/pubmed/33884653 Genetic Modifiers of Age at Onset for Parkinson's Disease in Asians: A Genome-Wide Association Study. Parkinson's disease (age of onset) 3,456 Chinese ancestry individuals 1,490 Chinese ancestry individuals Illumina [~ 660000] (imputed) 2 Parkinson's disease, age at onset http://www.ebi.ac.uk/efo/EFO_0002508, http://www.ebi.ac.uk/efo/EFO_0004847 GCST011677 Genome-wide genotyping array 3456 2021-10-20 33891350 Vann CG 2021-05-01 FASEB J www.ncbi.nlm.nih.gov/pubmed/33891350 An intron variant of the GLI family zinc finger 3 (GLI3) gene differentiates resistance training-induced muscle fiber hypertrophy in younger men. Response to resistance training (vastus lateralis fiber area change) 109 men NR NR [315000] 2 NA NA GCST012493 Genome-wide genotyping array 109 2021-10-20 33891350 Vann CG 2021-05-01 FASEB J www.ncbi.nlm.nih.gov/pubmed/33891350 An intron variant of the GLI family zinc finger 3 (GLI3) gene differentiates resistance training-induced muscle fiber hypertrophy in younger men. Response to resistance training (lean soft tissue mass change) 109 men NR NR [315000] 0 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST012494 Genome-wide genotyping array 109 2021-09-10 33913524 Suzuki T 2021-04-29 Epilepsia www.ncbi.nlm.nih.gov/pubmed/33913524 Genome-wide association study of epilepsy in a Japanese population identified an associated region at chromosome 12q24. Epilepsy 1,823 Japanese ancestry cases, 7,970 Japanese ancestry controls NR Illumina [9899436] (imputed) 7 epilepsy http://www.ebi.ac.uk/efo/EFO_0000474 GCST012370 Genome-wide genotyping array 9793 2021-09-08 33898419 Mukhopadhyay N 2021-04-09 Front Cell Dev Biol www.ncbi.nlm.nih.gov/pubmed/33898419 Genome-Wide Association Study of Non-syndromic Orofacial Clefts in a Multiethnic Sample of Families and Controls Identifies Novel Regions. Nonsyndromic cleft lip with or without cleft palate 154 African ancestry cases, 274 African ancestry controls, 445 Asian ancestry cases, 1,246 Asian ancestry controls, 569 European ancestry cases, 2,704 European ancestry controls, 1,050 Central and South American cases, 2,988 Central and South American controls, 3 cases, 14 controls NA Illumina [NR] (imputed) 18 Oral cleft http://purl.obolibrary.org/obo/HP_0000202 GCST012337 Genome-wide genotyping array 9447 2021-05-20 33069728 Pu W 2020-10-15 J Invest Dermatol www.ncbi.nlm.nih.gov/pubmed/33069728 Exome-wide association analysis suggests LRP2BP as a susceptibility gene for endothelial injury in systemic sclerosis in Han Chinese population. Systemic sclerosis 527 Han Chinese ancestry cases, 5,024 Han Chinese ancestry controls 479 Han Chinese ancestry cases, 1,096 Han Chinese ancestry controls Illumina [84228] 4 systemic scleroderma http://www.ebi.ac.uk/efo/EFO_0000717 GCST011709 Exome genotyping array [Exome array] 5551 2021-09-08 33859377 Thorp JG 2021-04-15 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/33859377 Symptom-level modelling unravels the shared genetic architecture of anxiety and depression. Depression at least 5,919 European ancestry cases, at least 130,691 European ancestry controls 634,037 European ancestry cases, 1,308,690 European ancestry controls NR [9417325] (imputed) 47 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST012355 Genome-wide genotyping array 136610 2021-09-08 33859377 Thorp JG 2021-04-15 Nat Hum Behav www.ncbi.nlm.nih.gov/pubmed/33859377 Symptom-level modelling unravels the shared genetic architecture of anxiety and depression. Anxiety at least 23,606 European ancestry cases, at least 113,351 European ancestry controls 624,615 European ancestry cases, 1,310,854 European ancestry controls NR [9417325] (imputed) 55 anxiety measurement http://www.ebi.ac.uk/efo/EFO_0009863 GCST012354 Genome-wide genotyping array 136957 2021-05-10 32853455 Schwantes-An TH 2020-08-27 Hepatology www.ncbi.nlm.nih.gov/pubmed/32853455 Genome-wide association study and meta-analysis on alcohol-related liver cirrhosis identifies novel genetic risk factors. Cirrhosis (alcohol related) 1,128 European ancestry cases, 849 European ancestry heavy-drinking controls up to 2,369 European ancestry cases, up to 10,434 European ancestry heavy-drinking controls Illumina [9377111] (imputed) 14 alcoholic liver cirrhosis http://www.ebi.ac.uk/efo/EFO_1000802 GCST011639 Genome-wide genotyping array 1977 2021-05-13 31622379 Best LG 2019-10-17 PLoS One www.ncbi.nlm.nih.gov/pubmed/31622379 Genetic analysis of hsCRP in American Indians: The Strong Heart Family Study. C-reactive protein levels 1,892 American Indian ancestry individuals NA Illumina [120972] 3 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST011657 Targeted genotyping array [Cardio-MetaboChip] 1892 2021-05-18 33907307 Liu Y 2021-04-27 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/33907307 Genome-wide association study of neck circumference identifies sex-specific loci independent of generalized adiposity. Neck circumference 13,625 European ancestry individuals, 1,465 African American individuals NA Affymetrix, Illumina [8865513] (imputed) 4 neck circumference http://www.ebi.ac.uk/efo/EFO_0011043 GCST90017133 Genome-wide genotyping array 15090 2021-05-18 33907307 Liu Y 2021-04-27 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/33907307 Genome-wide association study of neck circumference identifies sex-specific loci independent of generalized adiposity. Neck circumference 6,358 European and African American ancestry women NA Affymetrix, Illumina [7322639] (imputed) 3 neck circumference http://www.ebi.ac.uk/efo/EFO_0011043 GCST90017134 Genome-wide genotyping array 6358 2021-05-18 33907307 Liu Y 2021-04-27 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/33907307 Genome-wide association study of neck circumference identifies sex-specific loci independent of generalized adiposity. Neck circumference 8,732 European American and African American ancestry men NA Affymetrix, Illumina [7784259] (imputed) 5 neck circumference http://www.ebi.ac.uk/efo/EFO_0011043 GCST90017135 Genome-wide genotyping array 8732 2021-05-18 33907307 Liu Y 2021-04-27 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/33907307 Genome-wide association study of neck circumference identifies sex-specific loci independent of generalized adiposity. Neck circumference (BMI adjusted) 13,625 European ancestry individuals, 1,465 African American individuals 3,297 European ancestry individuals Affymetrix, Illumina [8865513] (imputed) 2 BMI-adjusted neck circumference http://www.ebi.ac.uk/efo/EFO_0011044 GCST90017136 Genome-wide genotyping array 15090 2021-05-18 33907307 Liu Y 2021-04-27 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/33907307 Genome-wide association study of neck circumference identifies sex-specific loci independent of generalized adiposity. Neck circumference (BMI adjusted) 6,358 European and African American ancestry women 1,743 European ancestry women Affymetrix, Illumina [7322639] (imputed) 0 BMI-adjusted neck circumference http://www.ebi.ac.uk/efo/EFO_0011044 GCST90017137 Genome-wide genotyping array 6358 2021-05-18 33907307 Liu Y 2021-04-27 Int J Obes (Lond) www.ncbi.nlm.nih.gov/pubmed/33907307 Genome-wide association study of neck circumference identifies sex-specific loci independent of generalized adiposity. Neck circumference (BMI adjusted) 8,732 European and African American ancestry men 1,554 European ancestry men Affymetrix, Illumina [7789444] (imputed) 1 BMI-adjusted neck circumference http://www.ebi.ac.uk/efo/EFO_0011044 GCST90017138 Genome-wide genotyping array 8732 2021-05-17 33197388 Duckworth A 2020-11-13 Lancet Respir Med www.ncbi.nlm.nih.gov/pubmed/33197388 Telomere length and risk of idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease: a mendelian randomisation study. Idiopathic pulmonary fibrosis 1,369 European ancestry cases, 435,866 European ancestry controls NA Affymetrix [805426] (imputed) 0 idiopathic pulmonary fibrosis http://www.ebi.ac.uk/efo/EFO_0000768 GCST90018120 Genome-wide genotyping array 437235 2021-09-08 33832965 Sandoval-Plata G 2021-04-08 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/33832965 Variants in urate transporters, ADH1B, GCKR and MEPE genes associate with transition from asymptomatic hyperuricaemia to gout: results of the first gout versus asymptomatic hyperuricaemia GWAS in Caucasians using data from the UK Biobank. Gout 7,049 European ancestry cases, 64,424 European ancestry controls NA Affymetrix [710030] 34 gout http://www.ebi.ac.uk/efo/EFO_0004274 GCST012338 Genome-wide genotyping array 71473 2021-09-08 33832965 Sandoval-Plata G 2021-04-08 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/33832965 Variants in urate transporters, ADH1B, GCKR and MEPE genes associate with transition from asymptomatic hyperuricaemia to gout: results of the first gout versus asymptomatic hyperuricaemia GWAS in Caucasians using data from the UK Biobank. Gout vs asymptomatic hyperuricemia 4,934 European ancestry cases, 56,948 European ancestry controls 2,115 European ancestry cases, 24,406 European ancestry controls Affymetrix [710030] 13 gout http://www.ebi.ac.uk/efo/EFO_0004274 GCST012339 Genome-wide genotyping array 61882 2021-10-07 33990960 Hong M 2021-05-14 Eur J Clin Invest www.ncbi.nlm.nih.gov/pubmed/33990960 Ethnic similarities in genetic polymorphisms associated with atrial fibrillation: Far East Asian vs European populations. Atrial fibrillation 9,118 East Asian ancestry cases, 33,467 East Asian ancestry controls NA NR [2286360] (imputed) 14 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST012460 Genome-wide genotyping array 42585 2021-10-04 33976257 Yusuf I 2021-05-11 Sci Rep www.ncbi.nlm.nih.gov/pubmed/33976257 Genetic risk factors for colorectal cancer in multiethnic Indonesians. Colorectal cancer 89 Indonesian cases, 84 Indonesian controls NA Affymetrix [524765] (imputed) 3 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST012421 Genome-wide genotyping array 173 2020-11-07 32996047 Alsubaie LM 2020-09-29 Mol Biol Rep www.ncbi.nlm.nih.gov/pubmed/32996047 Risk Y-haplotypes and pathogenic variants of Arab-ancestry boys with autism by an exome-wide association study. Autism 47 Saudi Arab ancestry young male cases, 43 Saudi Arab ancestry young male controls NA Illumina [243345] 9 autism http://www.ebi.ac.uk/efo/EFO_0003758 GCST010733 Exome genotyping array [Exome array] 90 2008-09-17 17903305 Murabito JM 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903305 A genome-wide association study of breast and prostate cancer in the NHLBI's Framingham Heart Study. Prostate cancer 59 cases, 558 controls NA Affymetrix [70897] 5 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST000095 Genome-wide genotyping array 617 2008-09-10 17903305 Murabito JM 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903305 A genome-wide association study of breast and prostate cancer in the NHLBI's Framingham Heart Study. Breast cancer 58 cases, 665 controls NA Affymetrix [70897] 9 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST000079 Genome-wide genotyping array 723 2012-09-25 22843789 Baldwin RM 2012-07-27 Clin Cancer Res www.ncbi.nlm.nih.gov/pubmed/22843789 A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101. Paclitaxel-induced neuropathy 855 European ancestry breast cancer cases 154 European ancestry breast cancer cases, 117 African American breast cancer cases Illumina [521600] 0 response to paclitaxel, neuropathy http://purl.obolibrary.org/obo/GO_1901555, http://www.ebi.ac.uk/efo/EFO_0004149 GCST001624 Genome-wide genotyping array 855 2011-05-02 21460840 Hollingworth P 2011-04-03 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21460840 Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Alzheimer's disease 6,688 European ancestry cases, 13,685 European ancestry controls 13,182 European ancestry cases, 26,161 European ancestry controls Affymetrix, Illumina [496763] 4 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST001025 Genome-wide genotyping array 20373 2013-04-24 23354978 Rinella ES 2013-01-25 Hum Genet www.ncbi.nlm.nih.gov/pubmed/23354978 Genetic variants associated with breast cancer risk for Ashkenazi Jewish women with strong family histories but no identifiable BRCA1/2 mutation. Breast cancer 477 Ashkenazi Jewish cases, 524 Ashkenazi Jewish controls 203 Ashkenazi Jewish cases, 263 Ashkenazi Jewish contols Affymetrix [435632] 3 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST001831 Genome-wide genotyping array 1001 2008-09-16 18385739 Thorgeirsson TE 2008-04-03 Nature www.ncbi.nlm.nih.gov/pubmed/18385739 A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nicotine dependence 10,995 European ancestry individuals 4,848 European ancestry individuals Illumina [306207] 1 nicotine dependence http://www.ebi.ac.uk/efo/EFO_0003768 GCST000171 Genome-wide genotyping array 10995 2008-06-16 18385738 Hung RJ 2008-04-03 Nature www.ncbi.nlm.nih.gov/pubmed/18385738 A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Lung cancer 1,926 European ance other ancestry cases, 2,522 European and other ancestry controls 332 European ancestry cases, 462 European ancestry controls, 2,181 European and other ancestry cases, 4,290 European and other ancestry controls Illumina [310023] 1 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST000170 Genome-wide genotyping array 4448 2009-04-03 18711367 Yasuda K 2008-08-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18711367 Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Type 2 diabetes 187 Japanese ancestry cases, 1,504 Japanese ancestry controls 6,552 East Asian ancestry cases, 6,621 East Asian ancestry controls, 2,830 European ancestry cases, 3,740 European ancestry controls NR [82343] 1 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST000219 Genome-wide genotyping array 1691 2009-09-24 19714249 Liu YZ 2009-08-28 PLoS One www.ncbi.nlm.nih.gov/pubmed/19714249 Powerful bivariate genome-wide association analyses suggest the SOX6 gene influencing both obesity and osteoporosis phenotypes in males. Obesity and osteoporosis 499 European ancestry male individuals, 501 European ancestry female individuals 1,370 European ancestry male individuals and 1,985 European ancestry female individuals from 975 families Affymetrix [379319] 2 obesity, osteoporosis http://www.ebi.ac.uk/efo/EFO_0001073, http://www.ebi.ac.uk/efo/EFO_0003882 GCST000469 Genome-wide genotyping array 1000 2009-12-28 19950302 Zhou X 2009-11-30 Arthritis Rheum www.ncbi.nlm.nih.gov/pubmed/19950302 HLA-DPB1 and DPB2 are genetic loci for systemic sclerosis: a genome-wide association study in Koreans with replication in North Americans. Systemic sclerosis 133 Korean ancestry cases, 557 Korean ancestry controls 1,107 European ancestry cases, 2,747 European ancestry controls Affymetrix [440734] 0 systemic scleroderma http://www.ebi.ac.uk/efo/EFO_0000717 GCST000535 Genome-wide genotyping array 690 2011-12-24 22144915 Fan Q 2011-12-01 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22144915 Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism. Corneal astigmatism 1,231 Chinese ancestry cases, 785 Chinese ancestry controls, 1,018 Malay ancestry cases, 1,220 Malay ancestry controls 825 Indian ancestry cases, 1,314 Indian ancestry controls, 760 Chinese ancestry child cases, 169 Chinese ancestry child controls, 397 Chinese ancestry trios Illumina [460528] 6 Astigmatism http://purl.obolibrary.org/obo/HP_0000483 GCST001339 Genome-wide genotyping array 4254 2011-01-04 21061259 Plant D 2010-11-08 Arthritis Rheum www.ncbi.nlm.nih.gov/pubmed/21061259 Genome-wide association study of genetic predictors of anti-tumor necrosis factor treatment efficacy in rheumatoid arthritis identifies associations with polymorphisms at seven loci. Response to anti-TNF therapy in rheumatoid arthritis 566 European ancestry individuals 720 European ancestry individuals Affymetrix [459446] 0 response to TNF antagonist http://www.ebi.ac.uk/efo/EFO_0004653 GCST000865 Genome-wide genotyping array 566 2009-09-30 20061627 Heinzen EL 2009-09-11 J Alzheimers Dis www.ncbi.nlm.nih.gov/pubmed/20061627 Genome-wide scan of copy number variation in late-onset Alzheimer's disease. Alzheimer's disease 331 European ancestry cases, 368 European ancestry controls NA Illumina [~ 550000] 5 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST000484 Genome-wide genotyping array 699 2009-05-26 19442274 Fei Y 2009-05-14 Arthritis Res Ther www.ncbi.nlm.nih.gov/pubmed/19442274 Identification of novel genetic susceptibility loci for Behçet's disease using a genome-wide association study. Behcet's disease 152 cases, 170 controls NA Affymetrix [~ 500000] 0 Behcet's syndrome http://www.ebi.ac.uk/efo/EFO_0003780 GCST000399 Genome-wide genotyping array 322 2010-03-09 20154673 Van Deerlin VM 2010-02-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20154673 Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Frontotemporal lobar degeneration 515 European ancestry cases, 2,509 European ancestry controls 89 European ancestry cases, 553 European ancestry controls Illumina [~ 500000] 0 Pick disease http://www.ebi.ac.uk/efo/EFO_0003096 GCST000595 Genome-wide genotyping array 3024 2010-02-08 20081856 McMahon FJ 2010-01-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20081856 Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1. Major mood disorders 6,686 European ancestry cases, 9,068 European ancestry controls 1,930 European ancestry cases, 2,747 European ancestry controls Affymetrix, Illumina, Perlegen [~ 2100000] (imputed) 1 mood disorder http://www.ebi.ac.uk/efo/EFO_0004247 GCST000570 Genome-wide genotyping array 15754 2010-09-27 20808326 Krumbiegel M 2010-09-01 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/20808326 Genome-wide association study with DNA pooling identifies variants at CNTNAP2 associated with pseudoexfoliation syndrome. Pseudoexfoliation syndrome 160 European ancestry cases, 80 European ancestry controls 859 European ancestry cases, 554 European ancestry controls Affymetrix [~ 500000] 0 exfoliation syndrome http://www.ebi.ac.uk/efo/EFO_0004235 GCST000784 Genome-wide genotyping array 240 2010-09-22 20709820 Kong X 2010-08-13 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/20709820 Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema. Emphysema-related traits 2,383 European ancestry cases NA Illumina [499578] 7 emphysema http://www.ebi.ac.uk/efo/EFO_0000464 GCST000770 Genome-wide genotyping array 2383 2012-01-27 22182935 Chen DT 2011-12-20 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/22182935 Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. Bipolar disorder 5,568 European ancestry cases, 7,187 European ancestry controls, 1,000 Taiwanese ancestry cases, 1,000 Taiwanese ancestry controls 1,115 European ancestry cases, 2,728 European ancestry controls Affymetrix, Illumina [748555] 5 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST001358 Genome-wide genotyping array 14755 2008-09-09 17668382 Salonen JT 2007-06-26 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/17668382 Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium. Type 2 diabetes 201 Finland founder cases, 200 Finland founder controls, 200 Ashkenazi Jewish cases, 197 Ashkenazi Jewish controls, 99 European ancestry cases, 100 European ancestry controls 2,573 European ancestry cases, 2,776 European ancestry controls Illumina [315917] 2 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST000049 Genome-wide genotyping array 997 2009-02-28 19198613 Gudmundsson J 2009-02-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19198613 Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations. Thyroid cancer 192 European ancestry cases, 37,196 European ancestry controls 432 European ancestry cases, 1,727 European ancestry controls Illumina [304083] 2 thyroid carcinoma http://www.ebi.ac.uk/efo/EFO_0002892 GCST000335 Genome-wide genotyping array 37388 2009-02-07 19169255 Zhang XJ 2009-01-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19169255 Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21. Psoriasis 1,139 Han Chinese ancestry cases, 1,132 Han Chinese ancestry controls 5,721 Chinese ancestry cases, 7,340 Chinese ancestry controls Illumina [494902] 3 psoriasis http://www.ebi.ac.uk/efo/EFO_0000676 GCST000321 Genome-wide genotyping array 2271 2009-03-18 19252134 Pezzolesi MG 2009-02-27 Diabetes www.ncbi.nlm.nih.gov/pubmed/19252134 Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes. Type 2 diabetes nephropathy 820 European ancestry cases, 885 European ancestry controls 1,304 European ancestry individuals Affymetrix [359193] 0 diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0000401 GCST000348 Genome-wide genotyping array 1705 2008-06-16 18204098 Hom G 2008-01-20 N Engl J Med www.ncbi.nlm.nih.gov/pubmed/18204098 Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. Systemic lupus erythematosus 1,311 European ancestry cases, 3,340 European ancestry controls 793 European ancestry cases, 857 European ancestry controls Illumina [502033] 9 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST000144 Genome-wide genotyping array 4651 2010-03-17 20174558 Tsai FJ 2010-02-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/20174558 A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese. Type 2 diabetes 995 Han Chinese ancestry cases, 894 Han Chinese ancestry controls 1,803 Han Chinese ancestry cases, 1,473 Han Chinese ancestry controls Illumina [516737] 3 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST000601 Genome-wide genotyping array 1889 2011-01-16 21177295 Panoutsopoulou K 2010-12-21 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/21177295 Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study. Osteoarthritis 3,177 European ancestry cases, 4,894 European ancestry controls 10,312 European ancestry cases, 45,861 European ancestry controls, 213 cases, 2,531 controls Illumina [514898] 0 osteoarthritis http://www.ebi.ac.uk/efo/EFO_0002506 GCST000923 Genome-wide genotyping array 8071 2009-05-07 18839057 Lesch KP 2008-10-07 J Neural Transm (Vienna) www.ncbi.nlm.nih.gov/pubmed/18839057 Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies. Attention deficit hyperactivity disorder 343 European ancestry cases, 250 European ancestry controls, 54 controls NA Affymetrix [504219] 26 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST000246 Genome-wide genotyping array 647 2009-08-07 19584346 Vasan RS 2009-07-08 JAMA www.ncbi.nlm.nih.gov/pubmed/19584346 Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. Aortic root size 12,612 European ancestry individuals 4,094 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 6 aortic root size http://www.ebi.ac.uk/efo/EFO_0005037 GCST000442 Genome-wide genotyping array 12612 2009-08-07 19584346 Vasan RS 2009-07-08 JAMA www.ncbi.nlm.nih.gov/pubmed/19584346 Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. Cardiac structure and function 12,612 European ancestry individuals 4,094 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 4 cardiovascular measurement http://www.ebi.ac.uk/efo/EFO_0004298 GCST000441 Genome-wide genotyping array 12612 2010-04-12 20304771 Newman AB 2010-03-18 J Gerontol A Biol Sci Med Sci www.ncbi.nlm.nih.gov/pubmed/20304771 A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. Longevity 1,836 European ancestry long-lived individuals, 1,955 European ancestry controls 2,594 European ancestry long-lived individuals, 3,431 European ancestry controls Affymetrix, Illumina [2287520] (imputed) 1 longevity http://www.ebi.ac.uk/efo/EFO_0004300 GCST000632 Genome-wide genotyping array 3791 2009-12-01 19874204 Guo Y 2009-10-29 J Bone Miner Res www.ncbi.nlm.nih.gov/pubmed/19874204 IL21R and PTH may underlie variation of femoral neck bone mineral density as revealed by a genome-wide association study. Bone mineral density 983 European ancestry individuals 2,557 European ancestry individuals from 750 families Affymetrix [342854] 2 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST000515 Genome-wide genotyping array 983 2009-08-21 19648920 Wu X 2009-08-02 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19648920 Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer. Bladder cancer 969 European ancestry cases, 957 European ancestry controls 5,698 European ancestry cases, 38,633 European ancestry controls Illumina [556429] 1 bladder carcinoma http://www.ebi.ac.uk/efo/EFO_0000292 GCST000454 Genome-wide genotyping array 1926 2010-10-14 20871662 Fu YP 2010-09-02 J Ophthalmol www.ncbi.nlm.nih.gov/pubmed/20871662 Identification of Diabetic Retinopathy Genes through a Genome-Wide Association Study among Mexican-Americans from Starr County, Texas. Diabetic retinopathy 103 Mexican American cases, 183 Mexican American controls NA Affymetrix [421010] (imputed) 0 diabetic retinopathy http://www.ebi.ac.uk/efo/EFO_0003770 GCST000786 Genome-wide genotyping array 286 2009-11-09 19836008 Landi MT 2009-10-15 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/19836008 A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Lung adenocarcinoma 5,739 European ancestry cases, 5,848 European ancestry controls 7,561 European ancestry cases, 13,818 European ancestry controls Illumina [515922] 5 lung adenocarcinoma http://www.ebi.ac.uk/efo/EFO_0000571 GCST000506 Genome-wide genotyping array 11587 2013-03-26 23321320 Urabe Y 2013-01-12 J Hepatol www.ncbi.nlm.nih.gov/pubmed/23321320 A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region. Hepatitis C induced liver cirrhosis 682 Japanese ancestry cases, 1,045 Japanese ancestry controls 936 Japanese ancestry cases, 3,809 Japanese ancestry controls Illumina [431618] 5 hepatitis C induced liver cirrhosis http://www.ebi.ac.uk/efo/EFO_0005129 GCST001815 Genome-wide genotyping array 1727 2009-05-20 19426955 Himes BE 2009-05-07 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/19426955 Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene. Asthma 359 European ancestry cases, 846 European ancestry controls 2,981 European ancestry cases, 12,358 European ancestry controls, 769 European ancestry and hispanic cases, 1,007 European ancestry and hispanic controls, 592 Hispanic cases with their 1,184 Hispanic parental controls, 2,258 African American cases, 3,006 African American controls Illumina [518230] 1 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST000389 Genome-wide genotyping array 1205 2009-01-14 19114657 Wang Y 2008-12-29 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/19114657 From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene. Blood pressure 542 Old Order Amish individuals 5,229 European ancestry individuals, 1,347 Amish individuals, 575 Hutterite individuals Affymetrix [79447] 1 blood pressure http://www.ebi.ac.uk/efo/EFO_0004325 GCST000306 Genome-wide genotyping array 542 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pulmonary fibrosis 126 East Asian ancestry cases, 176,974 East Asian ancestry controls NA Illumina [13429783] (imputed) 1 pulmonary fibrosis http://www.ebi.ac.uk/efo/EFO_0009448 GCST90018688 Genome-wide genotyping array 177100 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pyelonephritis 1,811 East Asian ancestry cases, 175,288 East Asian ancestry controls NA Illumina [13429797] (imputed) 1 pyelonephritis http://www.ebi.ac.uk/efo/EFO_1001141 GCST90018689 Genome-wide genotyping array 177099 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Rheumatoid arthritis 5,348 East Asian ancestry cases, 173,268 East Asian ancestry controls NA Illumina [13429970] (imputed) 8 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST90018690 Genome-wide genotyping array 178616 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Retinal detachment 1,389 East Asian ancestry cases, 168,903 East Asian ancestry controls NA Illumina [13428804] (imputed) 0 retinal detachment http://www.ebi.ac.uk/efo/EFO_0005773 GCST90018691 Genome-wide genotyping array 170292 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Retinitis pigmentosa 155 East Asian ancestry cases, 168,903 East Asian ancestry controls NA Illumina [13428559] (imputed) 3 Retinitis pigmentosa http://www.orpha.net/ORDO/Orphanet_791 GCST90018692 Genome-wide genotyping array 169058 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Rheumatic fever 152 East Asian ancestry cases, 170,247 East Asian ancestry controls NA Illumina [13428587] (imputed) 0 susceptibility to rheumatic fever measurement http://www.ebi.ac.uk/efo/EFO_0008416 GCST90018693 Genome-wide genotyping array 170399 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Ringworm 692 East Asian ancestry cases, 178,034 East Asian ancestry controls NA Illumina [13429980] (imputed) 1 tinea http://www.ebi.ac.uk/efo/EFO_0007510 GCST90018694 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Stable angina pectoris 18,833 East Asian ancestry cases, 146,214 East Asian ancestry controls NA Illumina [13427711] (imputed) 28 angina pectoris http://www.ebi.ac.uk/efo/EFO_0003913 GCST90018695 Genome-wide genotyping array 165047 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Sleep apnea syndrome 473 East Asian ancestry cases, 177,864 East Asian ancestry controls NA Illumina [13429911] (imputed) 0 sleep apnea http://www.ebi.ac.uk/efo/EFO_0003877 GCST90018696 Genome-wide genotyping array 178337 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Systemic lupus erythematosus 317 East Asian ancestry cases, 175,937 East Asian ancestry controls NA Illumina [13429699] (imputed) 0 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST90018697 Genome-wide genotyping array 176254 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Sarcoidosis 220 East Asian ancestry cases, 177,667 East Asian ancestry controls NA Illumina [13429855] (imputed) 1 Sarcoidosis http://www.orpha.net/ORDO/Orphanet_797 GCST90018698 Genome-wide genotyping array 177887 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Schizophrenia 99 East Asian ancestry cases, 177,794 East Asian ancestry controls NA Illumina [13429798] (imputed) 0 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST90018699 Genome-wide genotyping array 177893 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Sjögren's syndrome 303 East Asian ancestry cases, 175,599 East Asian ancestry controls NA Illumina [13429612] (imputed) 1 Sjogren syndrome http://www.ebi.ac.uk/efo/EFO_0000699 GCST90018700 Genome-wide genotyping array 175902 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Skin cancer 154 East Asian ancestry cases, 178,572 East Asian ancestry controls NA Illumina [13429980] (imputed) 1 skin neoplasm http://www.ebi.ac.uk/efo/EFO_0004198 GCST90018701 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Spinal canal stenosis 661 East Asian ancestry cases, 178,065 East Asian ancestry controls NA Illumina [13429980] (imputed) 0 spinal stenosis http://www.ebi.ac.uk/efo/EFO_0007490 GCST90018702 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Subarachnoid hemorrhage 1,203 East Asian ancestry cases, 152,022 East Asian ancestry controls NA Illumina [13425781] (imputed) 1 subarachnoid hemorrhage http://www.ebi.ac.uk/efo/EFO_0000713 GCST90018703 Genome-wide genotyping array 153225 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Substance dependence 118 East Asian ancestry cases, 178,608 East Asian ancestry controls NA Illumina [13429980] (imputed) 1 drug dependence http://www.ebi.ac.uk/efo/EFO_0003890 GCST90018704 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Type 1 diabetes 1,219 East Asian ancestry cases, 132,032 East Asian ancestry controls NA Illumina [13421694] (imputed) 3 type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001359 GCST90018705 Genome-wide genotyping array 133251 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Type 2 diabetes 45,383 East Asian ancestry cases, 132,032 East Asian ancestry controls NA Illumina [13429769] (imputed) 104 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST90018706 Genome-wide genotyping array 177415 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Stevens-Johnson syndrome 93 East Asian ancestry cases, 171,753 East Asian ancestry controls NA Illumina [13429124] (imputed) 1 Stevens-Johnson syndrome http://www.ebi.ac.uk/efo/EFO_0004276 GCST90018707 Genome-wide genotyping array 171846 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Tatto pigmentation 224 East Asian ancestry cases, 178,502 East Asian ancestry controls NA Illumina [13429980] (imputed) 0 skin pigmentation http://www.ebi.ac.uk/efo/EFO_0003784 GCST90018708 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Thyroid cancer 361 East Asian ancestry cases, 178,362 East Asian ancestry controls NA Illumina [13429980] (imputed) 0 thyroid carcinoma http://www.ebi.ac.uk/efo/EFO_0002892 GCST90018709 Genome-wide genotyping array 178723 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Tonsillitis 420 East Asian ancestry cases, 151,846 East Asian ancestry controls NA Illumina [13425541] (imputed) 0 pharyngitis http://purl.obolibrary.org/obo/MONDO_0002258 GCST90018710 Genome-wide genotyping array 152266 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Typhoid fever 257 East Asian ancestry cases, 178,071 East Asian ancestry controls NA Illumina [13429923] (imputed) 0 typhoid fever http://www.ebi.ac.uk/efo/EFO_0006789 GCST90018711 Genome-wide genotyping array 178328 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Unstable angina pectoris 5,891 East Asian ancestry cases, 146,214 East Asian ancestry controls NA Illumina [13425416] (imputed) 13 angina pectoris http://www.ebi.ac.uk/efo/EFO_0003913 GCST90018712 Genome-wide genotyping array 152105 2008-06-27 18451265 Bouatia-Naji N 2008-06-19 Science www.ncbi.nlm.nih.gov/pubmed/18451265 A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels. Fasting plasma glucose 654 European ancestry individuals 9,353 European ancestry individuals Illumina [392935] 1 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST000205 Genome-wide genotyping array 654 2009-12-29 20031577 Danik JS 2009-04-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/20031577 Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study. Fibrinogen 17,686 European ancestry female individuals NA Illumina [337343] 6 fibrinogen measurement http://www.ebi.ac.uk/efo/EFO_0004623 GCST000368 Genome-wide genotyping array 17686 2008-07-22 18316681 Uhl GR 2008-03-01 Arch Gen Psychiatry www.ncbi.nlm.nih.gov/pubmed/18316681 Genome-wide association for methamphetamine dependence: convergent results from 2 samples. Methamphetamine dependence 240 East Asian ancestry cases, 340 East Asian ancestry controls NA Affymetrix [up to 466883] 0 methamphetamine dependence http://www.ebi.ac.uk/efo/EFO_0004701 GCST000156 Genome-wide genotyping array 580 2011-11-09 22010048 Wu X 2011-10-18 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22010048 A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23. Renal cell carcinoma 894 European ancestry cases, 1,516 European ancestry controls 3,772 European ancestry cases, 8,505 European ancestry controls Illumina [533191] 3 renal cell carcinoma http://www.ebi.ac.uk/efo/EFO_0000681 GCST001283 Genome-wide genotyping array 2410 2009-09-04 19680635 Alkelai A 2009-08-13 Psychopharmacology (Berl) www.ncbi.nlm.nih.gov/pubmed/19680635 Genome-wide association study of antipsychotic-induced parkinsonism severity among schizophrenia patients. Response to antipsychotic treatment 140 European ancestry cases, 117 European ancestry controls, 57 African American cases, 72 African American controls, 2 cases, 9 controls NA Affymetrix, Perlegen [495172] 1 response to antipsychotic drug http://purl.obolibrary.org/obo/GO_0097332 GCST000462 Genome-wide genotyping array 397 2015-05-27 21339755 Liu X 2011-02-22 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/21339755 A non-synonymous polymorphism in galactose mutarotase (GALM) is associated with serotonin transporter binding potential in the human thalamus: results of a genome-wide association study. 5-HTT brain serotonin transporter levels 16 European, African American and Hispanic unmedicated bipolar disorder cases, 17 European, African American and Hispanic unmedicated major depressive disorder cases, 22 controls 51 European ancestry individuals Illumina [93247] 1 brain serotonin transporter measurement http://www.ebi.ac.uk/efo/EFO_0004569 GCST000983 Genome-wide genotyping array 55 2008-09-17 18252221 Kayser M 2008-01-24 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/18252221 Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene. Iris color 925 Erasmus Rucphen individuals, 481 European ancestry females 5,575 European ancestry individuals, 1,292 Erasmus Rucphen individuals Affymetrix, Illumina [up to 500000] 1 eye color http://www.ebi.ac.uk/efo/EFO_0003949 GCST000146 Genome-wide genotyping array 1406 2010-11-23 20939080 Greenbaum L 2010-10-11 Mov Disord www.ncbi.nlm.nih.gov/pubmed/20939080 Evidence for association of the GLI2 gene with tardive dyskinesia in patients with chronic schizophrenia. Tardive dyskinesia in schizophrenia 88 European ancestry cases, 40 African American cases, 3 cases, 129 European ancestry controls, 62 African American controls, 5 controls 44 Ashkenazi Jewish Israeli cases, 33 Jewish Israeli cases, 52 Ashkenazi Jewish Israeli controls, 41 Jewish Israeli controls Perlegen [495172] 0 movement disorder http://www.ebi.ac.uk/efo/EFO_0004280 GCST000831 Genome-wide genotyping array 327 2009-08-21 19197363 Need AC 2009-02-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/19197363 A genome-wide investigation of SNPs and CNVs in schizophrenia. Schizophrenia 871 European ancestry cases, 863 European ancestry controls 1,460 European ancestry cases, 12,995 European ancestry controls Illumina [312565] 0 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST000336 Genome-wide genotyping array 1734 2009-02-27 19196962 Garcia-Barcelo MM 2009-02-05 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/19196962 Genome-wide association study identifies NRG1 as a susceptibility locus for Hirschsprung's disease. Hirschsprung disease 181 Chinese ancestry cases, 346 Chinese ancestry controls 190 Chinese ancestry cases, 510 Chinese ancestry controls Affymetrix [293836] 2 Hirschsprung disease http://www.orpha.net/ORDO/Orphanet_388 GCST000334 Genome-wide genotyping array 527 2009-02-27 19207018 Kim H 2009-02-01 Pharmacogenomics www.ncbi.nlm.nih.gov/pubmed/19207018 Genome-wide association study of acute post-surgical pain in humans. Pain 112 European ancestry individuals NA Affymetrix [374975] 3 pain http://www.ebi.ac.uk/efo/EFO_0003843 GCST000326 Genome-wide genotyping array 112 2010-06-21 20516156 Lewis CM 2010-06-01 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/20516156 Genome-wide association study of major recurrent depression in the U.K. population. Major depressive disorder 1,636 European ancestry cases, 1,594 European ancestry controls 1,418 European ancestry cases, 1,918 European ancestry controls Illumina [471747] 4 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST000689 Genome-wide genotyping array 3230 2010-09-27 20802204 Baranzini SE 2010-09-01 Brain www.ncbi.nlm.nih.gov/pubmed/20802204 Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis. Multiple sclerosis--Brain Glutamate Levels 382 cases NA Illumina [~ 500000] 5 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST000783 Genome-wide genotyping array 382 2009-12-04 19897590 Schaefer AS 2009-11-06 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/19897590 A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis. Periodontitis 283 European ancestry cases, 972 European ancestry controls 155 European ancestry cases, 341 European ancestry controls Affymetrix [345646] 1 periodontitis http://www.ebi.ac.uk/efo/EFO_0000649 GCST000521 Genome-wide genotyping array 1255 2013-10-24 23563609 Wheeler E 2013-04-07 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23563609 Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity. Obesity (early onset extreme) 1,509 European ancestry cases, 5,380 European ancestry controls 971 European ancestry cases, 1,990 European ancestry controls Affymetrix [~ 2000000] (imputed) 18 obesity http://www.ebi.ac.uk/efo/EFO_0001073 GCST001957 Genome-wide genotyping array 6889 2009-08-21 19625618 Nakano M 2009-07-22 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/19625618 Three susceptible loci associated with primary open-angle glaucoma identified by genome-wide association study in a Japanese population. Glaucoma (primary open-angle) 418 Japanese ancestry cases, 300 Japanese ancestry controls 409 Japanese ancestry cases, 448 Japanese ancestry controls Affymetrix [331838] 0 open-angle glaucoma http://www.ebi.ac.uk/efo/EFO_0004190 GCST000449 Genome-wide genotyping array 718 2008-08-11 18668548 Julia A 2008-08-01 Arthritis Rheum www.ncbi.nlm.nih.gov/pubmed/18668548 Genome-wide association study of rheumatoid arthritis in the Spanish population: KLF12 as a risk locus for rheumatoid arthritis susceptibility. Rheumatoid arthritis 400 European ancestry cases, 400 European ancestry controls 410 European ancestry cases, 394 European ancestry controls Illumina [299918] 2 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST000217 Genome-wide genotyping array 800 2012-02-21 22282500 Chien JW 2012-01-26 Blood www.ncbi.nlm.nih.gov/pubmed/22282500 Evaluation of published single nucleotide polymorphisms associated with acute GVHD. Acute graft versus host disease 1,298 Allogenic hematopoietic cell transplantation donors and recipients NA Affymetrix [NR] (imputed) 0 acute graft vs. host disease http://www.ebi.ac.uk/efo/EFO_0004599 GCST001386 Genome-wide genotyping array 1298 2008-11-12 18835860 Mushiroda T 2008-10-01 J Med Genet www.ncbi.nlm.nih.gov/pubmed/18835860 A genome-wide association study identifies an association of a common variant in TERT with susceptibility to idiopathic pulmonary fibrosis. Idiopathic pulmonary fibrosis 159 Japanese ancestry cases, 934 Japanese ancestry controls 83 Japanese ancestry cases, 535 Japanese ancestry controls Illumina [214508] 1 idiopathic pulmonary fibrosis http://www.ebi.ac.uk/efo/EFO_0000768 GCST000238 Genome-wide genotyping array 1093 2008-06-16 18326623 Gold B 2008-03-11 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/18326623 Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33. Breast cancer 249 Ashkenazi Jewish non-BRCA1/2 carriers cases, 299 Ashkenazi Jewish non-BRCA1/2 carriers controls 1,193 Ashkenazi Jewish non-BRCA1/2 carriers cases,1,166 Ashkenazi Jewish non-BRCA1/2 carriers controls Affymetrix [150080] 1 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST000162 Genome-wide genotyping array 554 2009-05-28 19448620 Perry JR 2009-05-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19448620 Meta-analysis of genome-wide association data identifies two loci influencing age at menarche. Menarche (age at onset) 17,510 European ancestry female individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 2 age at menarche http://www.ebi.ac.uk/efo/EFO_0004703 GCST000404 Genome-wide genotyping array 17510 2009-06-01 19448623 Ong KK 2009-05-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19448623 Genetic variation in LIN28B is associated with the timing of puberty. Menarche (age at onset) 4,714 European ancestry female individuals 16,373 European ancestry female individuals Affymetrix [up to 390631] 1 age at menarche http://www.ebi.ac.uk/efo/EFO_0004703 GCST000405 Genome-wide genotyping array 4714 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Hepatic cancer 2,122 East Asian ancestry cases, 159,201 East Asian ancestry controls NA Illumina [13427386] (imputed) 4 liver neoplasm http://www.ebi.ac.uk/efo/EFO_1001513 GCST90018638 Genome-wide genotyping array 161323 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Herpes infection 772 East Asian ancestry cases, 166,603 East Asian ancestry controls NA Illumina [13427944] (imputed) 0 Herpes simplex infection http://www.ebi.ac.uk/efo/EFO_1002022 GCST90018639 Genome-wide genotyping array 167375 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Hyperthyroidism 994 East Asian ancestry cases, 172,656 East Asian ancestry controls NA Illumina [13429005] (imputed) 0 Hyperthyroidism http://www.ebi.ac.uk/efo/EFO_0009189 GCST90018640 Genome-wide genotyping array 173650 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Hypertrophic cardiomyopathy 383 East Asian ancestry cases, 177,745 East Asian ancestry controls NA Illumina [13429920] (imputed) 0 hypertrophic cardiomyopathy http://www.ebi.ac.uk/efo/EFO_0000538 GCST90018641 Genome-wide genotyping array 178128 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Hypothyroidism 1,114 East Asian ancestry cases, 172,656 East Asian ancestry controls NA Illumina [13429045] (imputed) 7 hypothyroidism http://www.ebi.ac.uk/efo/EFO_0004705 GCST90018642 Genome-wide genotyping array 173770 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Interstitial lung disease 1,046 East Asian ancestry cases, 176,974 East Asian ancestry controls NA Illumina [13429875] (imputed) 3 interstitial lung disease http://www.ebi.ac.uk/efo/EFO_0004244 GCST90018643 Genome-wide genotyping array 178020 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Ischemic stroke 22,664 East Asian ancestry cases, 152,022 East Asian ancestry controls NA Illumina [13429439] (imputed) 5 Ischemic stroke http://purl.obolibrary.org/obo/HP_0002140 GCST90018644 Genome-wide genotyping array 174686 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Idiopathic thrombocytopenic purpura 168 East Asian ancestry cases, 178,558 East Asian ancestry controls NA Illumina [13429980] (imputed) 0 autoimmune thrombocytopenic purpura http://www.ebi.ac.uk/efo/EFO_0007160 GCST90018645 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. IgA nephropathy 71 East Asian ancestry cases, 175,288 East Asian ancestry controls NA Illumina [13429474] (imputed) 0 IGA glomerulonephritis http://www.ebi.ac.uk/efo/EFO_0004194 GCST90018646 Genome-wide genotyping array 175359 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Ileus 1,771 East Asian ancestry cases, 176,232 East Asian ancestry controls NA Illumina [13429884] (imputed) 0 ileus http://purl.obolibrary.org/obo/MONDO_0004567 GCST90018647 Genome-wide genotyping array 178003 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Inguinal hernia 1,664 East Asian ancestry cases, 177,062 East Asian ancestry controls NA Illumina [13429980] (imputed) 1 Inguinal hernia http://purl.obolibrary.org/obo/HP_0000023 GCST90018648 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Insomnia 389 East Asian ancestry cases, 177,864 East Asian ancestry controls NA Illumina [13429894] (imputed) 1 insomnia measurement http://www.ebi.ac.uk/efo/EFO_0007876 GCST90018649 Genome-wide genotyping array 178253 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Intracerebral hemorrhage 1,456 East Asian ancestry cases, 152,022 East Asian ancestry controls NA Illumina [13425819] (imputed) 1 intracerebral hemorrhage http://www.ebi.ac.uk/efo/EFO_0005669 GCST90018650 Genome-wide genotyping array 153478 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Iritis 110 East Asian ancestry cases, 175,543 East Asian ancestry controls NA Illumina [13429677] (imputed) 2 iritis http://www.ebi.ac.uk/efo/EFO_1000997 GCST90018651 Genome-wide genotyping array 175653 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Iron deficiency anemia 4,618 East Asian ancestry cases, 174,057 East Asian ancestry controls NA Illumina [13429953] (imputed) 1 anemia (phenotype) http://www.ebi.ac.uk/efo/EFO_0004272 GCST90018652 Genome-wide genotyping array 178675 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Juvenile rheumatoid arthritis 110 East Asian ancestry cases, 173,268 East Asian ancestry controls NA Illumina [13429185] (imputed) 0 juvenile idiopathic arthritis http://www.ebi.ac.uk/efo/EFO_0002609 GCST90018653 Genome-wide genotyping array 173378 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Keloid 1,055 East Asian ancestry cases, 177,671 East Asian ancestry controls NA Illumina [13429980] (imputed) 4 Keloid http://www.ebi.ac.uk/efo/EFO_0004212 GCST90018654 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Lung cancer 4,444 East Asian ancestry cases, 174,282 East Asian ancestry controls NA Illumina [13429980] (imputed) 8 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST90018655 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Myasthenia gravis 81 East Asian ancestry cases, 178,630 East Asian ancestry controls NA Illumina [13429979] (imputed) 0 Myasthenia gravis http://www.ebi.ac.uk/efo/EFO_0004991 GCST90018656 Genome-wide genotyping array 178711 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Myocardial infarction 14,992 East Asian ancestry cases, 146,214 East Asian ancestry controls NA Illumina [13427135] (imputed) 39 myocardial infarction http://www.ebi.ac.uk/efo/EFO_0000612 GCST90018657 Genome-wide genotyping array 161206 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Malignant lymphoma 335 East Asian ancestry cases, 177,342 East Asian ancestry controls NA Illumina [13429812] (imputed) 1 lymphoma http://www.ebi.ac.uk/efo/EFO_0000574 GCST90018658 Genome-wide genotyping array 177677 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Mastopathy 575 East Asian ancestry cases, 82,186 East Asian ancestry controls NA Illumina [13403071] (imputed) 0 breast fibrocystic disease http://www.ebi.ac.uk/efo/EFO_0003014 GCST90018659 Genome-wide genotyping array 82761 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Meniere's disease 1,290 East Asian ancestry cases, 177,436 East Asian ancestry controls NA Illumina [13429980] (imputed) 1 Meniere disease http://www.ebi.ac.uk/efo/EFO_0006862 GCST90018660 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Metal allergy 278 East Asian ancestry cases, 161,777 East Asian ancestry controls NA Illumina [13427091] (imputed) 0 allergy http://www.ebi.ac.uk/efo/EFO_0003785 GCST90018661 Genome-wide genotyping array 162055 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Myocarditis 102 East Asian ancestry cases, 177,745 East Asian ancestry controls NA Illumina [13429830] (imputed) 0 myocarditis http://www.ebi.ac.uk/efo/EFO_0009609 GCST90018662 Genome-wide genotyping array 177847 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Nasal polyps 160 East Asian ancestry cases, 151,846 East Asian ancestry controls NA Illumina [13425583] (imputed) 0 Nasal Cavity Polyp http://www.ebi.ac.uk/efo/EFO_1000391 GCST90018663 Genome-wide genotyping array 152006 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Nephrotic syndrome 1,314 East Asian ancestry cases, 177,412 East Asian ancestry controls NA Illumina [13429980] (imputed) 1 nephrotic syndrome http://www.ebi.ac.uk/efo/EFO_0004255 GCST90018664 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Neuropathic bladder 308 East Asian ancestry cases, 178,418 East Asian ancestry controls NA Illumina [13429980] (imputed) 1 bladder disease http://www.ebi.ac.uk/efo/EFO_1000018 GCST90018665 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Non-tuberculous mycobacterial infection 64 East Asian ancestry cases, 172,320 East Asian ancestry controls NA Illumina [13428847] (imputed) 0 Mycobacterium infection http://www.ebi.ac.uk/efo/EFO_0009429 GCST90018666 Genome-wide genotyping array 172384 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Osteoporosis 9,794 East Asian ancestry cases, 168,932 East Asian ancestry controls NA Illumina [13429980] (imputed) 0 osteoporosis http://www.ebi.ac.uk/efo/EFO_0003882 GCST90018667 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Ovarian cancer 843 East Asian ancestry cases, 60,614 East Asian ancestry controls NA Illumina [13381302] (imputed) 0 ovarian carcinoma http://www.ebi.ac.uk/efo/EFO_0001075 GCST90018668 Genome-wide genotyping array 61457 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Ovarian cyst 2,896 East Asian ancestry cases, 79,865 East Asian ancestry controls NA Illumina [13403071] (imputed) 0 Ovarian cyst http://purl.obolibrary.org/obo/HP_0000138 GCST90018669 Genome-wide genotyping array 82761 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Peripheral artery disease 4,112 East Asian ancestry cases, 173,601 East Asian ancestry controls NA Illumina [13429824] (imputed) 3 peripheral arterial disease http://www.ebi.ac.uk/efo/EFO_0004265 GCST90018670 Genome-wide genotyping array 177713 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Polymyositis 58 East Asian ancestry cases, 175,599 East Asian ancestry controls NA Illumina [13429616] (imputed) 1 polymyositis http://www.ebi.ac.uk/efo/EFO_0003063 GCST90018671 Genome-wide genotyping array 175657 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pulmonary tuberculosis 7,800 East Asian ancestry cases, 170,871 East Asian ancestry controls NA Illumina [13429952] (imputed) 1 pulmonary tuberculosis http://www.ebi.ac.uk/efo/EFO_1000049 GCST90018672 Genome-wide genotyping array 178671 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pancreatic cancer 499 East Asian ancestry cases, 159,201 East Asian ancestry controls NA Illumina [13427108] (imputed) 1 pancreatic carcinoma http://www.ebi.ac.uk/efo/EFO_0002618 GCST90018673 Genome-wide genotyping array 159700 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Parkinson's disease 340 East Asian ancestry cases, 175,788 East Asian ancestry controls NA Illumina [13429429] (imputed) 0 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST90018674 Genome-wide genotyping array 176128 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pediatric asthma 547 East Asian ancestry cases, 161,803 East Asian ancestry controls NA Illumina [13427081] (imputed) 0 childhood onset asthma http://www.ebi.ac.uk/efo/EFO_0004591 GCST90018675 Genome-wide genotyping array 162350 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pericarditis 89 East Asian ancestry cases, 177,745 East Asian ancestry controls NA Illumina [13429854] (imputed) 0 pericarditis http://www.ebi.ac.uk/efo/EFO_0007427 GCST90018676 Genome-wide genotyping array 177834 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Periodontal disease 9,560 East Asian ancestry cases, 169,166 East Asian ancestry controls NA Illumina [13429980] (imputed) 0 periodontitis http://www.ebi.ac.uk/efo/EFO_0000649 GCST90018677 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pharyngeal and laryngeal cancer 300 East Asian ancestry cases, 178,426 East Asian ancestry controls NA Illumina [13429980] (imputed) 0 pharynx cancer, laryngeal carcinoma http://www.ebi.ac.uk/efo/EFO_0005577, http://purl.obolibrary.org/obo/MONDO_0002358 GCST90018678 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pleurisy 541 East Asian ancestry cases, 176,974 East Asian ancestry controls NA Illumina [13429832] (imputed) 0 pleurisy http://www.ebi.ac.uk/efo/EFO_1001825 GCST90018679 Genome-wide genotyping array 177515 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pneumoconiosis 85 East Asian ancestry cases, 176,974 East Asian ancestry controls NA Illumina [13429760] (imputed) 0 pneumoconiosis http://www.orpha.net/ORDO/Orphanet_182098 GCST90018680 Genome-wide genotyping array 177059 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pneumonia 7,423 East Asian ancestry cases, 171,303 East Asian ancestry controls NA Illumina [13429980] (imputed) 2 pneumonia http://www.ebi.ac.uk/efo/EFO_0003106 GCST90018681 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pneumothorax 692 East Asian ancestry cases, 176,298 East Asian ancestry controls NA Illumina [13429753] (imputed) 0 pneumothorax http://purl.obolibrary.org/obo/MONDO_0002076 GCST90018682 Genome-wide genotyping array 176990 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pollinosis 18,593 East Asian ancestry cases, 153,666 East Asian ancestry controls NA Illumina [13429010] (imputed) 4 seasonal allergic rhinitis http://www.ebi.ac.uk/efo/EFO_0003956 GCST90018683 Genome-wide genotyping array 172259 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Polycystic kidney disease 510 East Asian ancestry cases, 178,216 East Asian ancestry controls NA Illumina [13429980] (imputed) 0 Polycystic Kidney Disease http://www.ebi.ac.uk/efo/EFO_0008620 GCST90018684 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Prostate cancer 5,672 East Asian ancestry cases, 84,660 East Asian ancestry controls NA Illumina [13406905] (imputed) 23 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST90018685 Genome-wide genotyping array 90332 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Preeclampsia 123 East Asian ancestry cases, 81,962 East Asian ancestry controls NA Illumina [13402395] (imputed) 0 preeclampsia http://www.ebi.ac.uk/efo/EFO_0000668 GCST90018686 Genome-wide genotyping array 82085 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Psoriasis vulgaris 206 East Asian ancestry cases, 172,289 East Asian ancestry controls NA Illumina [13429050] (imputed) 1 psoriasis vulgaris http://www.ebi.ac.uk/efo/EFO_1001494 GCST90018687 Genome-wide genotyping array 172495 2008-06-22 18454148 Loos RJ 2008-05-04 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18454148 Common variants near MC4R are associated with fat mass, weight and risk of obesity. Body mass index 16,876 European ancestry adult individuals 60,352 European ancestry adult individuals, 5,988 European ancestry children Affymetrix [344883] 2 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST000185 Genome-wide genotyping array 16876 2012-03-03 22306654 Feenstra B 2012-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22306654 Common variants near MBNL1 and NKX2-5 are associated with infantile hypertrophic pyloric stenosis. Infantile hypertrophic pyloric stenosis 1,001 European ancestry cases, 2,401 European ancestry controls 796 European ancestry cases, 876 European ancestry controls Illumina [523420] 5 infantile hypertrophic pyloric stenosis http://www.ebi.ac.uk/efo/EFO_0004707 GCST001399 Genome-wide genotyping array 3402 2008-06-22 18454146 Chambers JC 2008-05-04 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18454146 Common genetic variation near MC4R is associated with waist circumference and insulin resistance. Waist circumference and related phenotypes 2,684 Indian Asian ancestry male individuals 7,394 Indian Asian ancestry individuals, 4,561 European ancestry individuals Illumina [308067] 4 waist circumference, triglyceride measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004342, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0004612 GCST000184 Genome-wide genotyping array 2684 2009-02-05 19081515 Mead S 2008-12-11 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/19081515 Genetic risk factors for variant Creutzfeldt-Jakob disease: a genome-wide association study. Creutzfeldt-Jakob disease 117 European ancestry cases, 3,083 European ancestry controls 2 European ancestry vCJD cases, 506 Oceania ancestry sCJD cases, 28 Oceania ancestry iCJD cases, 151 Oceania ancestry Kuru cases, 125 Oceania ancestry Kuru resistant cases, 3,608 European ancestry controls, 562 Oceania ancestry controls Affymetrix [288908] 2 Creutzfeldt Jacob Disease http://www.ebi.ac.uk/efo/EFO_0004226 GCST000294 Genome-wide genotyping array 3200 2010-09-10 20686608 Low SK 2010-07-29 PLoS One www.ncbi.nlm.nih.gov/pubmed/20686608 Genome-wide association study of pancreatic cancer in Japanese population. Pancreatic cancer 991 Japanese ancestry cases, 5,209 Japanese ancestry controls NA Illumina [420236] 17 pancreatic carcinoma http://www.ebi.ac.uk/efo/EFO_0002618 GCST000745 Genome-wide genotyping array 6200 2010-10-05 20835239 Solouki AM 2010-09-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20835239 A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14. Refractive error 5,328 European ancestry individuals 10,280 European ancestry individuals Illumina [~ 2500000] (imputed) 1 Abnormality of refraction http://purl.obolibrary.org/obo/HP_0000539 GCST000795 Genome-wide genotyping array 5328 2008-06-16 17529967 Easton DF 2007-05-27 Nature www.ncbi.nlm.nih.gov/pubmed/17529967 Genome-wide association study identifies novel breast cancer susceptibility loci. Breast cancer 390 European ancestry cases, 364 European ancestry controls 4,364 East Asian ancestry cases, 24,174 European ancestry controls, 3,564 East Asian ancestry controls, 24,391 European ancestry controls Perlegen [205586] 6 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST000035 Genome-wide genotyping array 754 2013-10-31 20558996 Ott J 2010-06-17 Hum Hered www.ncbi.nlm.nih.gov/pubmed/20558996 Pilot study on schizophrenia in Sardinia. Schizophrenia 14 Sardinian cases, 23 Sardinian controls NA Affymetrix [255053] 0 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST000702 Genome-wide genotyping array 37 2009-12-29 20031582 Thompson JF 2009-04-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/20031582 Comprehensive whole-genome and candidate gene analysis for response to statin therapy in the Treating to New Targets (TNT) cohort. Response to statin therapy 1,984 European ancestry individuals 3,761 European ancestry individuals, 1,248 individuals Perlegen [291998] 0 response to statin http://purl.obolibrary.org/obo/GO_0036273 GCST000369 Genome-wide genotyping array 1984 2009-12-18 19944697 Karlsen TH 2009-11-25 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/19944697 Genome-wide association analysis in primary sclerosing cholangitis. Primary sclerosing cholangitis 285 European ancestry cases, 298 European ancestry controls 766 European ancestry cases, 2,935 European ancestry controls Affymetrix [375487] 0 sclerosing cholangitis http://www.ebi.ac.uk/efo/EFO_0004268 GCST000534 Genome-wide genotyping array 583 2012-03-10 22228203 Aslibekyan S 2012-01-05 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/22228203 A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network. Inflammatory biomarkers 1,092 European ancestry individuals NA Affymetrix [2543887] (imputed) 19 response to fenofibrate http://purl.obolibrary.org/obo/GO_1901557 GCST001371 Genome-wide genotyping array 1092 2009-01-21 19124843 Ober C 2009-01-07 J Lipid Res www.ncbi.nlm.nih.gov/pubmed/19124843 Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q. Lp (a) levels 357 Hutterite individuals 1,054 European ancestry males Affymetrix [290327] 1 apolipoprotein A 1 measurement http://www.ebi.ac.uk/efo/EFO_0004614 GCST000312 Genome-wide genotyping array 357 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Colorectal cancer 8,305 East Asian ancestry cases, 159,386 East Asian ancestry controls NA Illumina [13428297] (imputed) 14 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST90018588 Genome-wide genotyping array 167691 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic suppurative otitis media 2,206 East Asian ancestry cases, 176,520 East Asian ancestry controls NA Illumina [13429980] (imputed) 0 suppurative otitis media http://www.ebi.ac.uk/efo/EFO_0007503 GCST90018589 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Cesarian section 451 East Asian ancestry cases, 82,310 East Asian ancestry controls NA Illumina [13403071] (imputed) 0 cesarean section http://www.ebi.ac.uk/efo/EFO_0009636 GCST90018590 Genome-wide genotyping array 82761 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Cardiac valvular disease 1,995 East Asian ancestry cases, 176,731 East Asian ancestry controls NA Illumina [13429980] (imputed) 0 heart valve disease http://www.ebi.ac.uk/efo/EFO_0009551 GCST90018591 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Cardiomegaly 743 East Asian ancestry cases, 177,983 East Asian ancestry controls NA Illumina [13429980] (imputed) 0 cardiac hypertrophy http://www.ebi.ac.uk/efo/EFO_0002503 GCST90018592 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Carpal tunnel syndrome 192 East Asian ancestry cases, 178,534 East Asian ancestry controls NA Illumina [13429980] (imputed) 1 carpal tunnel syndrome http://www.ebi.ac.uk/efo/EFO_0004143 GCST90018593 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Cataracts 38,194 East Asian ancestry cases, 140,532 East Asian ancestry controls NA Illumina [13429980] (imputed) 2 cataract http://www.ebi.ac.uk/efo/EFO_0001059 GCST90018594 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Cerebral aneurysm 3,132 East Asian ancestry cases, 152,022 East Asian ancestry controls NA Illumina [13426064] (imputed) 4 brain aneurysm http://www.ebi.ac.uk/efo/EFO_0003870 GCST90018595 Genome-wide genotyping array 155154 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Unruptured cerebral aneurysm 91 East Asian ancestry cases, 152,022 East Asian ancestry controls NA Illumina [13425573] (imputed) 1 brain aneurysm http://www.ebi.ac.uk/efo/EFO_0003870 GCST90018596 Genome-wide genotyping array 152113 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Cervical cancer 967 East Asian ancestry cases, 60,614 East Asian ancestry controls NA Illumina [13381745] (imputed) 2 cervical carcinoma http://www.ebi.ac.uk/efo/EFO_0001061 GCST90018597 Genome-wide genotyping array 61581 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Cholecystitis 1,860 East Asian ancestry cases, 168,253 East Asian ancestry controls NA Illumina [13428642] (imputed) 0 Cholecystitis http://purl.obolibrary.org/obo/HP_0001082 GCST90018598 Genome-wide genotyping array 170113 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Cholelithiasis 9,305 East Asian ancestry cases, 168,253 East Asian ancestry controls NA Illumina [13429768] (imputed) 15 cholelithiasis http://www.ebi.ac.uk/efo/EFO_0004799 GCST90018599 Genome-wide genotyping array 177558 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic glomerulonephritis 210 East Asian ancestry cases, 174,345 East Asian ancestry controls NA Illumina [13429313] (imputed) 0 glomerulonephritis http://purl.obolibrary.org/obo/MONDO_0002462 GCST90018600 Genome-wide genotyping array 174555 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic pancreatitis 457 East Asian ancestry cases, 177,471 East Asian ancestry controls NA Illumina [13429808] (imputed) 1 pancreatitis http://www.ebi.ac.uk/efo/EFO_0000278 GCST90018601 Genome-wide genotyping array 177928 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic renal failure 2,117 East Asian ancestry cases, 174,345 East Asian ancestry controls NA Illumina [13429586] (imputed) 0 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST90018602 Genome-wide genotyping array 176462 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic sinusitis 4,617 East Asian ancestry cases, 152,226 East Asian ancestry controls NA Illumina [13426486] (imputed) 5 chronic rhinosinusitis http://www.ebi.ac.uk/efo/EFO_1000024 GCST90018603 Genome-wide genotyping array 156843 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic bronchitis 271 East Asian ancestry cases, 161,803 East Asian ancestry controls NA Illumina [13427039] (imputed) 1 chronic bronchitis http://www.ebi.ac.uk/efo/EFO_0006505 GCST90018604 Genome-wide genotyping array 162074 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic gastritis 744 East Asian ancestry cases, 177,982 East Asian ancestry controls NA Illumina [13429980] (imputed) 0 chronic gastritis http://www.ebi.ac.uk/efo/EFO_0000337 GCST90018605 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Cirrhosis 2,551 East Asian ancestry cases, 176,175 East Asian ancestry controls NA Illumina [13429980] (imputed) 5 cirrhosis of liver http://www.ebi.ac.uk/efo/EFO_0001422 GCST90018606 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Colon polyp 4,768 East Asian ancestry cases, 166,052 East Asian ancestry controls NA Illumina [13428894] (imputed) 1 polyp of colon http://purl.obolibrary.org/obo/MONDO_0021400 GCST90018607 Genome-wide genotyping array 170820 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Compression fracture 2,856 East Asian ancestry cases, 175,870 East Asian ancestry controls NA Illumina [13429980] (imputed) 0 bone fracture http://www.ebi.ac.uk/efo/EFO_0003931 GCST90018608 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Constipation 397 East Asian ancestry cases, 176,232 East Asian ancestry controls NA Illumina [13429711] (imputed) 0 Constipation http://purl.obolibrary.org/obo/HP_0002019 GCST90018609 Genome-wide genotyping array 176629 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Contact dermatitis 247 East Asian ancestry cases, 161,777 East Asian ancestry controls NA Illumina [13427082] (imputed) 0 contact dermatitis http://www.ebi.ac.uk/efo/EFO_0005319 GCST90018610 Genome-wide genotyping array 162024 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Cystitis 1,665 East Asian ancestry cases, 175,288 East Asian ancestry controls NA Illumina [13429618] (imputed) 0 cystitis http://www.ebi.ac.uk/efo/EFO_1000025 GCST90018611 Genome-wide genotyping array 176953 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Diabetic nephropathy 220 East Asian ancestry cases, 132,764 East Asian ancestry controls NA Illumina [13421642] (imputed) 0 diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0000401 GCST90018612 Genome-wide genotyping array 132984 2010-09-21 20694011 Ferreira RC 2010-08-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20694011 Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency. Immunoglobulin A 430 European ancestry cases, 1,090 European ancestry controls 342 European ancestry cases, 886 European ancestry controls Illumina [2057134] (imputed) 12 protein measurement http://www.ebi.ac.uk/efo/EFO_0004747 GCST000763 Genome-wide genotyping array 1520 2009-01-12 19047183 Friedman RA 2008-12-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/19047183 GRM7 variants confer susceptibility to age-related hearing impairment. Hearing impairment 846 European ancestry cases, 846 European ancestry controls 63 European ancestry cases, 67 European ancestry controls Affymetrix [506627] 0 hearing loss http://www.ebi.ac.uk/efo/EFO_0004238 GCST000275 Genome-wide genotyping array 1692 2009-11-25 19846067 Garriock HA 2009-10-19 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/19846067 A genomewide association study of citalopram response in major depressive disorder. Response to citalopram treatment Up to 659 European ancestry responders, up to 121 African American responders, up to 103 Hispanic responders, 408 European ancestry non-responders, 120 African American non-responders, 80 Hispanic non-responders NA Affymetrix [430198] 7 response to antidepressant http://purl.obolibrary.org/obo/GO_0036276 GCST000509 Genome-wide genotyping array 1491 2010-01-13 20018283 Heid IM 2009-12-02 Atherosclerosis www.ncbi.nlm.nih.gov/pubmed/20018283 Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals. Adiponectin levels 4,659 European ancestry individuals 13,795 European ancestry individuals Affymetrix, Illumina [2585854] (imputed) 1 adiponectin measurement http://www.ebi.ac.uk/efo/EFO_0004502 GCST000537 Genome-wide genotyping array 4659 2013-08-20 23583979 den Hoed M 2013-04-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23583979 Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Heart rate 85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals 88,823 European ancestry individuals Affymetrix, Illumina [2516789] (imputed) 32 heart rate http://www.ebi.ac.uk/efo/EFO_0004326 GCST001969 Genome-wide genotyping array 92355 2009-09-09 19668339 Potkin SG 2009-08-07 PLoS One www.ncbi.nlm.nih.gov/pubmed/19668339 Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease. Hippocampal atrophy 162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases NA Illumina [516645] 21 hippocampal atrophy http://www.ebi.ac.uk/efo/EFO_0005039 GCST000461 Genome-wide genotyping array 381 2010-01-13 20031538 Heid IM 2008-10-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/20031538 Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions. HDL cholesterol Up to 4,274 European ancestry individuals Up to 15,873 European ancestry individuals Affymetrix [up to 2557253] (imputed) 3 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST000240 Genome-wide genotyping array 4274 2009-12-29 20031604 Cheng YC 2009-08-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/20031604 Genome-wide association scan identifies variants near Matrix Metalloproteinase (MMP) genes on chromosome 11q21-22 strongly associated with serum MMP-1 levels. Matrix metalloproteinase levels 778 Old Order Amish individuals NA Affymetrix [338079] 4 matrix metalloproteinase measurement http://www.ebi.ac.uk/efo/EFO_0004744 GCST000450 Genome-wide genotyping array 778 2009-02-25 19165155 Ling H 2009-01-22 Obesity (Silver Spring) www.ncbi.nlm.nih.gov/pubmed/19165155 Genome-wide linkage and association analyses to identify genes influencing adiponectin levels: the GEMS Study. Adiponectin levels 997 European ancestry cases, 989 European ancestry controls NA Affymetrix [398625] 2 adiponectin measurement http://www.ebi.ac.uk/efo/EFO_0004502 GCST000319 Genome-wide genotyping array 1986 2009-03-01 19230858 Schrauwen I 2009-02-18 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/19230858 A genome-wide analysis identifies genetic variants in the RELN gene associated with otosclerosis. Otosclerosis 302 cases, 302 controls 847 cases, 872 controls Illumina [~ 555000] 1 otosclerosis http://www.ebi.ac.uk/efo/EFO_0004213 GCST000345 Genome-wide genotyping array 604 2009-03-01 19198612 Erdmann J 2009-02-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19198612 New susceptibility locus for coronary artery disease on chromosome 3q22.3. Coronary heart disease 1,222 European ancestry cases, 1,298 European ancestry controls 18,185 European ancestry cases, 20,068 European ancestry controls Affymetrix [567119] 2 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST000338 Genome-wide genotyping array 2520 2009-02-28 19187332 Kim SH 2009-02-01 Clin Exp Allergy www.ncbi.nlm.nih.gov/pubmed/19187332 Alpha-T-catenin (CTNNA3) gene was identified as a risk variant for toluene diisocyanate-induced asthma by genome-wide association analysis. Asthma (toluene diisocyanate-induced) 84 Korean ancestry cases, 263 Korean ancestry controls NA Affymetrix [312978] 3 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST000330 Genome-wide genotyping array 347 2009-02-26 19176441 Yang JJ 2009-01-28 JAMA www.ncbi.nlm.nih.gov/pubmed/19176441 Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia. Response to treatment for acute lymphoblastic leukemia 356 European ancestry cases, 53 Black cases, 78 cases NA Affymetrix [476796] 12 acute lymphoblastic leukemia, response to antineoplastic agent http://www.ebi.ac.uk/efo/EFO_0000220, http://purl.obolibrary.org/obo/GO_0097327 GCST000323 Genome-wide genotyping array 487 2009-06-30 19525955 Bahlo M 2009-06-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19525955 Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. Multiple sclerosis 1,618 European ancestry cases, 3,413 European ancestry controls 2,256 European ancestry cases, 2,310 European ancestry controls Illumina [302098] 8 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST000425 Genome-wide genotyping array 5031 2013-11-13 23696099 Ding K 2013-05-20 G3 (Bethesda) www.ncbi.nlm.nih.gov/pubmed/23696099 Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study. Red blood cell traits 1904 African American individuals 411 African American individuals Illumina [907954] 7 erythrocyte indices http://www.ebi.ac.uk/efo/EFO_0004306 GCST002027 Genome-wide genotyping array 1904 2013-08-24 23571587 Reitz C 2013-04-10 JAMA www.ncbi.nlm.nih.gov/pubmed/23571587 Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. Alzheimer's disease (late onset) 1,968 African American cases, 3,928 African American controls NA Illumina [17332474] (imputed) 2 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST001963 Genome-wide genotyping array 5896 2009-11-05 19820698 Chambers JC 2009-10-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19820698 Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels. Hemoglobin 6,316 European ancestry individuals, 9,685 Indian Asian ancestry individuals 5,187 European ancestry individuals, 6,721 Indian Asian ancestry individuals Affymetrix, Illumina, Perlegen [NR] 2 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST000501 Genome-wide genotyping array 16001 2015-05-13 21347282 Lettre G 2011-02-10 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21347282 Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. Coronary heart disease 260 African American cases, 5,053 African American controls 621 African American cases, 1,629 African American controls Affymetrix [~ 2740000] (imputed) 3 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST000972 Genome-wide genotyping array 5313 2015-05-13 21347282 Lettre G 2011-02-10 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21347282 Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. Type 2 diabetes 1,264 African American cases, 5,678 African American controls 503 African American cases, 1,656 African American controls Affymetrix [~ 2740000] (imputed) 2 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST000976 Genome-wide genotyping array 6942 2015-05-13 21347282 Lettre G 2011-02-10 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21347282 Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. LDL cholesterol 7,565 African American individuals 3,789 African American and Afro-Caribbean individuals Affymetrix [~ 2740000] (imputed) 17 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST000975 Genome-wide genotyping array 7565 2015-05-13 21347282 Lettre G 2011-02-10 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21347282 Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. HDL cholesterol 7,813 African American individuals 4,323 African American and Afro-Caribbean individuals Affymetrix [~ 2740000] (imputed) 18 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST000974 Genome-wide genotyping array 7813 2015-05-13 21347282 Lettre G 2011-02-10 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21347282 Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. Hypertension 4,069 African American cases, 3,848 African American controls 1,372 African American cases, 1,482 African American controls Affymetrix [~ 2740000] (imputed) 8 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST000973 Genome-wide genotyping array 7917 2011-04-06 21383967 Zhernakova A 2011-02-24 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21383967 Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. Celiac disease or Rheumatoid arthritis 4,533 European ancestry celiac disease cases, 5,539 European ancestry rheumatoid arthritis cases, 27,981 European ancestry controls 2,169 European ancestry celiac disease cases, 2,845 European ancestry rheumatoid arthritis cases, 7,199 European ancestry controls Illumina [472854] 15 immune system disease http://www.ebi.ac.uk/efo/EFO_0000540 GCST000987 Genome-wide genotyping array 38053 2010-09-23 20729853 Wang LD 2010-08-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20729853 Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54. Esophageal cancer 1,077 Han Chinese ancestry cases, 1,733 Han Chinese ancestry controls 7,673 Han Chinese ancestry cases, 11,013 Han Chinese ancestry controls, 303 Uygur-Kazakh Chinese ancestry cases, 537 Uygur-Kazakh Chinese ancestry controls Illumina [506666] 0 esophageal carcinoma http://www.ebi.ac.uk/efo/EFO_0002916 GCST000776 Genome-wide genotyping array 2810 2008-09-12 18391950 Lettre G 2008-04-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18391950 Identification of ten loci associated with height highlights new biological pathways in human growth. Height 15,821 European ancestry individuals Up to 17,801 European ancestry individuals Affymetrix, Illumina [2260683] (imputed) 18 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST000176 Genome-wide genotyping array 15821 2013-04-18 23337944 Haghighi A 2013-01-22 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/23337944 Opioid receptor mu 1 gene, fat intake and obesity in adolescence. Fat intake 598 European ancestry adolescents 490 European ancestry young adult individuals Illumina [530011] 0 energy intake http://www.ebi.ac.uk/efo/EFO_0003939 GCST001829 Genome-wide genotyping array 598 2010-03-30 20212171 Buil A 2010-03-08 Blood www.ncbi.nlm.nih.gov/pubmed/20212171 C4BPB/C4BPA is a new susceptibility locus for venous thrombosis with unknown protein S-independent mechanism: results from genome-wide association and gene expression analyses followed by case-control studies. C4b binding protein levels 352 European ancestry related individuals NA Illumina [283437] 1 C4BP measurement http://www.ebi.ac.uk/efo/EFO_0004572 GCST000621 Genome-wide genotyping array 352 2015-05-29 21323541 Stanescu HC 2011-02-22 N Engl J Med www.ncbi.nlm.nih.gov/pubmed/21323541 Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy. Idiopathic membranous nephropathy 556 European ancestry cases, 2,338 European ancestry controls NA Illumina [242824] 21 membranous glomerulonephritis http://www.ebi.ac.uk/efo/EFO_0004254 GCST000984 Genome-wide genotyping array 2894 2011-05-11 21499248 Kumar V 2011-04-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21499248 Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma. Hepatocellular carcinoma 721 Japanese ancestry cases, 2,890 Japanese ancestry controls 673 Japanese ancestry cases, 2,596 Japanese ancestry controls Illumina [432703] 2 hepatocellular carcinoma http://www.ebi.ac.uk/efo/EFO_0000182 GCST001041 Genome-wide genotyping array 3611 2010-02-28 20112360 Kerkhof HJ 2010-01-07 Arthritis Rheum www.ncbi.nlm.nih.gov/pubmed/20112360 A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22. Osteoarthritis 1,341 European ancestry cases, 3,496 European ancestry controls 9,779 European ancestry cases, up to 31,818 European ancestry controls, 3,818 cases, 7,278 controls Illumina [500510] 1 osteoarthritis http://www.ebi.ac.uk/efo/EFO_0002506 GCST000558 Genome-wide genotyping array 4837 2009-06-15 19483685 Daly AK 2009-05-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19483685 HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. Drug-induced liver injury (flucloxacillin) 58 European ancestry cases, 282 European ancestry controls NA Illumina [866399] 6 drug-induced liver injury http://www.ebi.ac.uk/efo/EFO_0004228 GCST000415 Genome-wide genotyping array 340 2009-07-01 19561606 Thorleifsson G 2009-06-28 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19561606 Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density. Kidney stones 1,507 European ancestry cases, 34,033 European ancestry controls 2,266 European ancestry cases, 8,477 European ancestry controls Illumina [303120] 1 nephrolithiasis http://www.ebi.ac.uk/efo/EFO_0004253 GCST000429 Genome-wide genotyping array 35540 2009-07-01 19553259 Cotsapas C 2009-06-24 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/19553259 Common body mass index-associated variants confer risk of extreme obesity. Obesity (extreme) 775 European ancestry cases, 3,197 European ancestry controls NA Illumina [457251] 13 obesity http://www.ebi.ac.uk/efo/EFO_0001073 GCST000426 Genome-wide genotyping array 3972 2009-09-04 19656524 Grant SF 2009-08-03 J Pediatr www.ncbi.nlm.nih.gov/pubmed/19656524 A genome-wide association study identifies a locus for nonsyndromic cleft lip with or without cleft palate on 8q24. Orofacial clefts 111 European ancestry cases, 5,951 European ancestry controls NA Illumina [495858] 2 cleft lip http://www.ebi.ac.uk/efo/EFO_0003959 GCST000458 Genome-wide genotyping array 6062 2011-05-26 21493818 Shaw SY 2011-04-21 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/21493818 Genetic and clinical correlates of early-outgrowth colony-forming units. Monocyte early outgrowth colony forming units 1,654 European ancestry individuals NA Affymetrix [~ 2500000] (imputed) 3 monocyte early outgrowth colony forming unit http://www.ebi.ac.uk/efo/EFO_0004506 GCST001048 Genome-wide genotyping array 1654 2013-04-24 21497773 Ziliak D 2011-02-08 Transl Res www.ncbi.nlm.nih.gov/pubmed/21497773 Germline polymorphisms discovered via a cell-based, genome-wide approach predict platinum response in head and neck cancers. Response to platinum-based chemotherapy in head and neck cancers 90 East Asian ancestry lymphoblastoid cell lines 90 European ancestry lymphoblastoid cell lines, 59 Yoruban ancestry lymphoblastoid cell lines NR [~ 2000000] 0 response to platinum based chemotherapy http://www.ebi.ac.uk/efo/EFO_0004647 GCST000968 Genome-wide genotyping array 90 2013-04-25 21497773 Ziliak D 2011-02-08 Transl Res www.ncbi.nlm.nih.gov/pubmed/21497773 Germline polymorphisms discovered via a cell-based, genome-wide approach predict platinum response in head and neck cancers. Response to platinum-based chemotherapy in head and neck cancers 90 European ancestry Lymphoblastoid cell lines NA NR [~ 2000000] 0 response to platinum based chemotherapy http://www.ebi.ac.uk/efo/EFO_0004647 GCST000967 Genome-wide genotyping array 90 2010-04-27 20372150 Freathy RM 2010-04-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20372150 Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Birth weight 10,623 European ancestry individuals 27,591 European ancestry individuals, 1,415 Filipino ancestry individuals, 746 North African ancestry individuals, 333 Turkish ancestry individuals Affymetrix, Illumina [~ 2400000] (imputed) 2 birth weight http://www.ebi.ac.uk/efo/EFO_0004344 GCST000648 Genome-wide genotyping array 10623 2008-10-14 18776929 Liu YZ 2008-09-08 PLoS One www.ncbi.nlm.nih.gov/pubmed/18776929 Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study. Hip bone size 501 European ancestry female individuals, 499 European ancestry male individuals 1,216 European ancestry female individuals Affymetrix [306823] 1 hip bone size http://www.ebi.ac.uk/efo/EFO_0004844 GCST000229 Genome-wide genotyping array 1000 2008-07-22 18332876 Kirov G 2008-03-11 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/18332876 A genome-wide association study in 574 schizophrenia trios using DNA pooling. Schizophrenia 574 European ancestry trios, 605 European ancestry controls NA Illumina [~ 550000] 1 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST000163 Genome-wide genotyping array 1179 2010-09-11 20670164 Horinouchi M 2010-08-01 Pediatr Hematol Oncol www.ncbi.nlm.nih.gov/pubmed/20670164 Association of genetic polymorphisms with hepatotoxicity in patients with childhood acute lymphoblastic leukemia or lymphoma. Acute lymphoblastic leukemia (childhood) 8 Japanese ancestry cases 16 Japanese ancestry cases Illumina [~ 318000] 0 acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000220 GCST000749 Genome-wide genotyping array 8 2010-09-02 20639880 Liu X 2010-07-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20639880 Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis. Primary biliary cholangitis 453 European ancestry cases, 945 European ancestry controls, 481 European ancestry cases, 3,706 European ancestry controls Illumina [276459] 6 biliary liver cirrhosis http://www.ebi.ac.uk/efo/EFO_0004267 GCST000733 Genome-wide genotyping array 1398 2009-08-21 19620980 Skibola CF 2009-07-20 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19620980 Genetic variants at 6p21.33 are associated with susceptibility to follicular lymphoma. Follicular lymphoma 189 European ancestry cases, 592 European controls 456 European ancestry cases, 2,785 European ancestry controls Illumina [~ 500000] 1 neoplasm of mature B-cells http://www.ebi.ac.uk/efo/EFO_0000096 GCST000448 Genome-wide genotyping array 781 2009-05-07 19389651 Smith JG 2009-02-15 Heart Rhythm www.ncbi.nlm.nih.gov/pubmed/19389651 Genome-wide association study of electrocardiographic conduction measures in an isolated founder population: Kosrae. Electrocardiographic conduction measures 1,262 Kosraen individuals NA Affymetrix [338049] 7 electrocardiography http://www.ebi.ac.uk/efo/EFO_0004327 GCST000344 Genome-wide genotyping array 1262 2008-11-12 18823527 Abraham R 2008-09-29 BMC Med Genomics www.ncbi.nlm.nih.gov/pubmed/18823527 A genome-wide association study for late-onset Alzheimer's disease using DNA pooling. Alzheimer's disease 1,082 European ancestry cases, 1,239 European ancestry controls 1,400 controls Illumina [561494] 2 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST000237 Genome-wide genotyping array 2321 2009-01-14 19074352 Pollin TI 2008-12-17 Science www.ncbi.nlm.nih.gov/pubmed/19074352 A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection. Triglycerides 809 Old Order Amish individuals 698 Old Order Amish individuals Affymetrix [381934] 1 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST000300 Genome-wide genotyping array 809 2008-09-15 17641165 Fellay J 2007-07-19 Science www.ncbi.nlm.nih.gov/pubmed/17641165 A whole-genome association study of major determinants for host control of HIV-1. HIV-1 viral setpoint 486 European ancestry cases 140 European ancestry cases Illumina [535101] 0 response to virus http://purl.obolibrary.org/obo/GO_0009615 GCST000059 Genome-wide genotyping array 486 2009-09-28 17903292 Hwang SJ 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903292 A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study. Cystatin C levels 981 individuals NA Affymetrix [70897] 1 cystatin C measurement http://www.ebi.ac.uk/efo/EFO_0004617 GCST000091 Genome-wide genotyping array 981 2008-09-02 17903292 Hwang SJ 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903292 A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study. Thyroid stimulating hormone levels 883 individuals NA Affymetrix [70897] 3 thyroid stimulating hormone measurement http://www.ebi.ac.uk/efo/EFO_0004748 GCST000100 Genome-wide genotyping array 883 2008-09-11 17903292 Hwang SJ 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903292 A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study. Urinary albumin excretion 822 individuals NA Affymetrix [70897] 2 albuminuria http://www.ebi.ac.uk/efo/EFO_0004285 GCST000105 Genome-wide genotyping array 822 2010-01-29 20062061 Chambers JC 2010-01-10 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20062061 Genetic variation in SCN10A influences cardiac conduction. Electrocardiographic traits 6,543 Indian Asian ancestry individuals 6,243 Indian Asian ancestry individuals, 5,370 European ancestry individuals Illumina [303309] 3 electrocardiography http://www.ebi.ac.uk/efo/EFO_0004327 GCST000564 Genome-wide genotyping array 6543 2009-09-28 18403759 Ober C 2008-04-09 N Engl J Med www.ncbi.nlm.nih.gov/pubmed/18403759 Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function. YKL-40 levels 632 Hutterite individuals 443 European ancestry cases, 491 European ancestry controls, 206 European ancestry individuals Affymetrix [290325] 1 YKL40 measurement http://www.ebi.ac.uk/efo/EFO_0004869 GCST000177 Genome-wide genotyping array 632 2010-02-04 20068591 Van Laer L 2010-01-13 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/20068591 A genome-wide association study for age-related hearing impairment in the Saami. Hearing impairment 347 Finnish Saami individuals NA Affymetrix [83381] 2 hearing loss http://www.ebi.ac.uk/efo/EFO_0004238 GCST000566 Genome-wide genotyping array 347 2009-09-28 19729612 Paterson AD 2009-09-03 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/19729612 Genome-wide association identifies the ABO blood group as a major locus associated with serum levels of soluble E-selectin. Soluble E-selectin levels 685 European ancestry individuals with type 1 diabetes 477 European ancestry individuals Illumina [~ 841000] 1 e-selectin measurement http://www.ebi.ac.uk/efo/EFO_0004575 GCST000476 Genome-wide genotyping array 686 2009-09-09 19714205 Hancock DB 2009-08-28 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/19714205 Genome-wide association study implicates chromosome 9q21.31 as a susceptibility locus for asthma in mexican children. Asthma (childhood onset) 492 Mexican ancestry trios 177 Mexican ancestry trios Illumina [520767] 1 childhood onset asthma http://www.ebi.ac.uk/efo/EFO_0004591 GCST000468 Genome-wide genotyping array 492 2011-01-03 21037115 Wan ES 2010-10-29 Am J Respir Cell Mol Biol www.ncbi.nlm.nih.gov/pubmed/21037115 Genome-wide association analysis of body mass in chronic obstructive pulmonary disease. Body mass in chronic obstructive pulmonary disease 2,950 European ancestry cases 502 European ancestry cases Illumina [~ 550000] 1 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST000850 Genome-wide genotyping array 2950 2009-03-31 19287509 Cui J 2009-03-14 Mol Med www.ncbi.nlm.nih.gov/pubmed/19287509 Genome-wide association study of determinants of anti-cyclic citrullinated peptide antibody titer in adults with rheumatoid arthritis. Anti-cyclic Citrullinated Peptide Antibody 531 European ancestry cases 849 European ancestry cases Affymetrix [97248] 1 anti-cyclic citrullinated peptide antibody measurement http://www.ebi.ac.uk/efo/EFO_0004733 GCST000356 Genome-wide genotyping array 531 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Alanine aminotransferase levels 342,387 European ancestry individuals, 6,017 African ancestry individuals, 7,325 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 189 serum alanine aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004735 GCST90019492 Genome-wide genotyping array 355729 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Serum albumin levels 313,032 European ancestry individuals, 5,573 African ancestry individuals, 6,687 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 202 serum albumin measurement http://www.ebi.ac.uk/efo/EFO_0004535 GCST90019493 Genome-wide genotyping array 325292 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Serum alkaline phosphatase levels 342,535 European ancestry individuals, 6,019 African ancestry individuals, 7,337 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 715 alkaline phosphatase measurement http://www.ebi.ac.uk/efo/EFO_0004533 GCST90019494 Genome-wide genotyping array 355891 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Apolipoprotein A1 levels 311,601 European ancestry individuals, 5,550 African ancestry individuals, 6,682 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 454 apolipoprotein A 1 measurement http://www.ebi.ac.uk/efo/EFO_0004614 GCST90019495 Genome-wide genotyping array 323833 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Apolipoprotein B levels 340,860 European ancestry individuals, 5,962 African ancestry individuals, 7,275 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 593 apolipoprotein B measurement http://www.ebi.ac.uk/efo/EFO_0004615 GCST90019496 Genome-wide genotyping array 354097 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Aspartate aminotransferase levels 341,246 European ancestry individuals, 5,982 African ancestry individuals, 7,313 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 265 aspartate aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004736 GCST90019497 Genome-wide genotyping array 354541 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Aspartate aminotransferase to alanine aminotransferase ratio 341,165 European ancestry individuals, 5,981 African ancestry individuals, 7,309 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 226 aspartate aminotransferase to alanine aminotransferase ratio http://www.ebi.ac.uk/efo/EFO_0010934 GCST90019498 Genome-wide genotyping array 354455 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. C-reactive protein levels 341,805 European ancestry individuals, 6,006 African ancestry individuals, 7,316 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 351 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST90019499 Genome-wide genotyping array 355127 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Calcium levels 313,387 European ancestry individuals, 5,576 African ancestry individuals, 6,696 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 208 calcium measurement http://www.ebi.ac.uk/efo/EFO_0004838 GCST90019500 Genome-wide genotyping array 325659 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Total cholesterol levels 342,508 European ancestry individuals, 6,014 African ancestry individuals, 7,336 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 596 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST90019501 Genome-wide genotyping array 355858 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Creatinine levels 342,376 European ancestry individuals, 6,016 African ancestry individuals, 7,339 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 359 creatinine measurement http://www.ebi.ac.uk/efo/EFO_0004518 GCST90019502 Genome-wide genotyping array 355731 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Urinary creatinine levels 333,115 European ancestry individuals, 5,789 African ancestry individuals, 7,009 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 7 creatinine measurement http://www.ebi.ac.uk/efo/EFO_0004518 GCST90019503 Genome-wide genotyping array 345913 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Cystatin C levels 342,399 European ancestry individuals, 6,015 African ancestry individuals, 7,338 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 360 cystatin C measurement http://www.ebi.ac.uk/efo/EFO_0004617 GCST90019504 Genome-wide genotyping array 355752 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Direct bilirubin levels 291,512 European ancestry individuals, 5,007 African ancestry individuals, 6,088 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 206 bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004570 GCST90019505 Genome-wide genotyping array 302607 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Estimated glomerular filtration rate 342,376 European ancestry individuals, 6,016 African ancestry individuals, 7,339 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 349 glomerular filtration rate http://www.ebi.ac.uk/efo/EFO_0005208 GCST90019506 Genome-wide genotyping array 355731 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Gamma glutamyl transferase levels 342,339 European ancestry individuals, 6,015 African ancestry individuals, 7,336 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 424 serum gamma-glutamyl transferase measurement http://www.ebi.ac.uk/efo/EFO_0004532 GCST90019507 Genome-wide genotyping array 355690 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Blood glucose levels 313,125 European ancestry individuals, 5,568 African ancestry individuals, 6,693 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 121 glucose measurement http://www.ebi.ac.uk/efo/EFO_0004468 GCST90019508 Genome-wide genotyping array 325386 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Glycated hemoglobin levels 327,177 European ancestry individuals, 4,847 African ancestry individuals, 6,895 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 470 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST90019509 Genome-wide genotyping array 338919 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. High density lipoprotein cholesterol levels 313,372 European ancestry individuals, 5,573 African ancestry individuals, 6,689 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 519 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST90019510 Genome-wide genotyping array 325634 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Insulin-like growth factor 1 levels 340,567 European ancestry individuals, 5,974 African ancestry individuals, 7,283 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 459 IGF-1 measurement http://www.ebi.ac.uk/efo/EFO_0004627 GCST90019511 Genome-wide genotyping array 353824 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Low density lipoprotein cholesterol levels 341,875 European ancestry individuals, 6,003 African ancestry individuals, 7,319 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 563 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST90019512 Genome-wide genotyping array 355197 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Lipoprotein (a) levels 272,573 European ancestry individuals, 5,018 African ancestry individuals, 6,453 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 194 lipoprotein A measurement http://www.ebi.ac.uk/efo/EFO_0006925 GCST90019513 Genome-wide genotyping array 284044 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Urinary microalbumin levels 102,944 European ancestry individuals, 2,679 African ancestry individuals, 2,560 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 6 urinary microalbumin measurement http://www.ebi.ac.uk/efo/EFO_0010967 GCST90019514 Genome-wide genotyping array 108183 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Non-albumin protein levels 313,032 European ancestry individuals, 5,573 African ancestry individuals, 6,687 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 336 serum non-albumin protein measurement http://www.ebi.ac.uk/efo/EFO_0004568 GCST90019515 Genome-wide genotyping array 325292 2021-06-29 33462484 Sinnott-Armstrong N 2021-01-18 Nat Genet www.ncbi.nlm.nih.gov/pubmed/33462484 Genetics of 35 blood and urine biomarkers in the UK Biobank. Serum phosphate levels 312,888 European ancestry individuals, 5,568 African ancestry individuals, 6,685 South Asian ancestry individuals NA Affymetrix [9000000] (imputed) 188 blood phosphate measurement http://www.ebi.ac.uk/efo/EFO_0010972 GCST90019516 Genome-wide genotyping array 325141 2009-07-10 19571809 Shi J 2009-07-01 Nature www.ncbi.nlm.nih.gov/pubmed/19571809 Common variants on chromosome 6p22.1 are associated with schizophrenia. Schizophrenia 2,681 European ancestry cases, 2,653 European ancestry controls, 1,286 African American cases, 973 African American controls 5,327 European ancestry cases, 16,424 European ancestry controls Affymetrix [up to 843798] 2 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST000433 Genome-wide genotyping array 7593 2010-01-19 20038947 Shyn SI 2009-12-29 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/20038947 Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies. Major depressive disorder (broad) 3,957 European ancestry cases, 3,428 European ancestry controls NA Affymetrix, Perlegen [2391203] (imputed) 9 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST000551 Genome-wide genotyping array 7385 2009-10-23 19812673 Weiss LA 2009-10-08 Nature www.ncbi.nlm.nih.gov/pubmed/19812673 A genome-wide linkage and association scan reveals novel loci for autism. Autism 1,553 cases from 1,031 families 2,073 trios Affymetrix [~ 365000] 2 autism http://www.ebi.ac.uk/efo/EFO_0003758 GCST000496 Genome-wide genotyping array 2584 2009-12-28 19929986 Craig DW 2009-11-01 Diabet Med www.ncbi.nlm.nih.gov/pubmed/19929986 Genome-wide SNP genotyping study using pooled DNA to identify candidate markers mediating susceptibility to end-stage renal disease attributed to Type 1 diabetes. End-stage renal disease 547 European ancestry cases, 549 European ancestry controls NA Illumina [474050] 0 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST000518 Genome-wide genotyping array 1096 2009-10-06 19786962 Roeske D 2009-09-29 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/19786962 First genome-wide association scan on neurophysiological endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic children. Speech perception in dyslexia 200 European ancestry cases 186 European ancestry cases Illumina [297086] 2 speech perception http://www.ebi.ac.uk/efo/EFO_0004336 GCST000492 Genome-wide genotyping array 200 2012-02-25 22286170 Cusanovich DA 2012-01-27 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22286170 The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes. Lymphocyte counts 462 Hutterite individuals NA Affymetrix [279749] 2 lymphocyte count http://www.ebi.ac.uk/efo/EFO_0004587 GCST001389 Genome-wide genotyping array 462 2009-06-26 19525478 Malarstig A 2009-06-12 Blood www.ncbi.nlm.nih.gov/pubmed/19525478 Identification of ZNF366 and PTPRD as novel determinants of plasma homocysteine in a family-based genome-wide association study. Homocysteine levels 387 European ancestry individuals from 21 families 1,238 individuals Illumina [283437] 0 homocysteine measurement http://www.ebi.ac.uk/efo/EFO_0004578 GCST000423 Genome-wide genotyping array 408 2010-10-15 20876614 Yoon KA 2010-09-28 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/20876614 A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population. Non-small cell lung cancer 621 Korean ancestry cases, 1,541 Korean ancestry controls 804 Korean ancestry cases, 1,470 Korean ancestry controls Affymetrix [246758] 3 non-small cell lung carcinoma http://www.ebi.ac.uk/efo/EFO_0003060 GCST000815 Genome-wide genotyping array 2162 2009-09-28 19729412 Tonjes A 2009-09-03 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/19729412 Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs. Height 929 Sorbian (founder/genetic isolate) individuals 5,758 European ancestry individuals Affymetrix [390619] 1 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST000475 Genome-wide genotyping array 929 2010-09-10 20673876 Rietschel M 2010-07-29 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/20673876 Genome-wide association-, replication-, and neuroimaging study implicates HOMER1 in the etiology of major depression. Major depressive disorder 597 European ancestry cases, 1,295 European ancestry controls 409 European ancestry cases, 541 European ancestry controls Illumina [491238] 3 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST000743 Genome-wide genotyping array 1892 2010-09-23 20801718 Laaksovirta H 2010-08-27 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/20801718 Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study. Amyotrophic lateral sclerosis 405 European ancestry cases, 497 European ancestry controls NA Illumina [318167] 2 amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0000253 GCST000781 Genome-wide genotyping array 902 2008-06-16 18264096 Thomas G 2008-02-10 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18264096 Multiple loci identified in a genome-wide association study of prostate cancer. Prostate cancer 1,172 European ancestry cases, 1,157 European ancestry controls 3,941 European ancestry cases, 3,964 European ancestry controls Illumina [527869] 7 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST000154 Genome-wide genotyping array 2329 2011-01-13 21051598 Pereyra F 2010-11-04 Science www.ncbi.nlm.nih.gov/pubmed/21051598 The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. HIV-1 control 516 European cases, 1,196 European controls, 341 African American cases, 892 African American controls, 117 Hispanic cases, 560 Hispanic controls NA Illumina [1384048] (imputed) 8 HIV-1 infection http://www.ebi.ac.uk/efo/EFO_0000180 GCST000863 Genome-wide genotyping array 3622 2009-05-11 19403135 Yamada Y 2009-04-05 Atherosclerosis www.ncbi.nlm.nih.gov/pubmed/19403135 Identification of CELSR1 as a susceptibility gene for ischemic stroke in Japanese individuals by a genome-wide association study. Stroke (ischemic) 131 Japanese ancestry cases, 135 Japanese ancestry controls 776 Japanese ancestry cases, 5,205 Japanese ancestry controls Affymetrix [~ 520000] 0 stroke http://www.ebi.ac.uk/efo/EFO_0000712 GCST000373 Genome-wide genotyping array 266 2009-06-22 19096518 Pare G 2008-12-19 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/19096518 Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study. Glycated hemoglobin levels 14,618 European ancestry females 455 European ancestry individuals Illumina [337343] 4 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST000303 Genome-wide genotyping array 14618 2013-05-08 23894747 Aberg KA 2013-02-01 JAMA Psychiatry www.ncbi.nlm.nih.gov/pubmed/23894747 A comprehensive family-based replication study of schizophrenia genes. Schizophrenia 11,185 European ancestry cases, 10,768 European ancestry controls 1,262 African American ancestry individuals, 2,740 European ancestry individuals, 2,296 Asian ancestry individuals NR [1085772] (imputed) 14 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST001851 Genome-wide genotyping array 21953 2008-09-08 17474819 Coon KD 2007-04-01 J Clin Psychiatry www.ncbi.nlm.nih.gov/pubmed/17474819 A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease. Alzheimer's disease (late onset) 664 European ancestry cases, 422 European ancestry controls NA Affymetrix [~ 502627] 1 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST000018 Genome-wide genotyping array 1086 2009-05-28 19448619 Stolk L 2009-05-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19448619 Loci at chromosomes 13, 19 and 20 influence age at natural menopause. Menopause (age at onset) 2,979 European ancestry female individuals 2,560 European ancestry female individuals Illumina [315418] 13 age at menopause http://www.ebi.ac.uk/efo/EFO_0004704 GCST000401 Genome-wide genotyping array 2979 2009-09-28 17407593 Uhl GR 2007-04-03 BMC Genet www.ncbi.nlm.nih.gov/pubmed/17407593 Molecular genetics of nicotine dependence and abstinence: whole genome association using 520,000 SNPs. Nicotine dependence 134 European ancestry cases, 320 European ancestry controls NA Affymetrix [~ 520000] 0 nicotine dependence http://www.ebi.ac.uk/efo/EFO_0003768 GCST000021 Genome-wide genotyping array 454 2008-06-16 17401363 Yeager M 2007-04-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/17401363 Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Prostate cancer 1,172 European ancestry cases, 1,157 European ancestry controls 3,124 European ancestry cases, 3,142 European ancestry controls Illumina [538548] 2 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST000017 Genome-wide genotyping array 2329 2009-06-04 19448621 He C 2009-05-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19448621 Genome-wide association studies identify loci associated with age at menarche and age at natural menopause. Menarche and menopause (age at onset) 17,438 European ancestry female individuals NA Illumina [317759] 6 age at menarche, age at menopause http://www.ebi.ac.uk/efo/EFO_0004703, http://www.ebi.ac.uk/efo/EFO_0004704 GCST000403 Genome-wide genotyping array 17438 2009-06-04 19461586 Norris JM 2009-05-21 Obesity (Silver Spring) www.ncbi.nlm.nih.gov/pubmed/19461586 Genome-wide association study and follow-up analysis of adiposity traits in Hispanic Americans: the IRAS Family Study. Obesity-related traits 229 Hispanic individuals from 34 families 961 Hispanic individuals from 59 families Illumina [309200] 0 adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004764 GCST000409 Genome-wide genotyping array 263 2009-06-29 19525953 De Jager PL 2009-06-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19525953 Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Multiple sclerosis 2,624 European ancestry cases, 7,220 European ancestry controls 2,215 European ancestry cases, 2,116 European ancestry controls Affymetrix, Illumina [~ 2560000] (imputed) 15 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST000424 Genome-wide genotyping array 9844 2009-08-12 19609347 Adeyemo A 2009-07-17 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/19609347 A genome-wide association study of hypertension and blood pressure in African Americans. Hypertension 509 African American cases, 508 African American controls 366 West African ancestry cases, 614 West African ancestry controls Affymetrix [808465] 2 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST000447 Genome-wide genotyping array 1017 2009-09-04 19684604 Papaemmanuil E 2009-08-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19684604 Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia. Acute lymphoblastic leukemia (childhood) 907 European ancestry cases, 2,398 European ancestry controls NA Illumina [291473] 3 acute lymphoblastic leukemia http://www.ebi.ac.uk/efo/EFO_0000220 GCST000463 Genome-wide genotyping array 3305 2010-10-15 20927387 Kullo IJ 2010-09-28 PLoS One www.ncbi.nlm.nih.gov/pubmed/20927387 A genome-wide association study of red blood cell traits using the electronic medical record. Red blood cell traits 3,012 European ancestry individuals NA Illumina [489421] 13 erythrocyte count, mean corpuscular hemoglobin concentration, mean corpuscular volume, mean corpuscular hemoglobin http://www.ebi.ac.uk/efo/EFO_0004305, http://www.ebi.ac.uk/efo/EFO_0004528, http://www.ebi.ac.uk/efo/EFO_0004526, http://www.ebi.ac.uk/efo/EFO_0004527 GCST000814 Genome-wide genotyping array 3012 2011-04-13 21441931 Okamoto K 2011-03-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21441931 Common variation in GPC5 is associated with acquired nephrotic syndrome. Nephrotic syndrome (acquired) 195 Japanese ancestry cases, 1,546 Japanese ancestry controls 662 Japanese ancestry cases, 4,919 Japanese ancestry controls Perlegen [205203] 2 nephrotic syndrome http://www.ebi.ac.uk/efo/EFO_0004255 GCST001018 Genome-wide genotyping array 1741 2008-06-16 16648850 Arking DE 2006-04-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/16648850 A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization. QT interval 100 European ancestry > 445ms female individuals, 100 European ancestry < 386ms female individuals 200 European ancestry > 85th pct female individuals, 200 European ancestry < 15th pct female individuals, 4,451 European ancestry individuals Affymetrix [88500] 1 QT interval http://www.ebi.ac.uk/efo/EFO_0004682 GCST000004 Genome-wide genotyping array 1031 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (vasodilators used in cardiac diseases) 17,050 East Asian ancestry cases, 161,676 East Asian ancestry controls NA Illumina [13429980] (imputed) 17 Vasodilators used in cardiac diseases use measurement http://www.ebi.ac.uk/efo/EFO_0009926 GCST90018763 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (antihypertensives) 5,688 East Asian ancestry cases, 173,038 East Asian ancestry controls NA Illumina [13134967] (imputed) 2 Antihypertensive use measurement http://www.ebi.ac.uk/efo/EFO_0009927 GCST90018764 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (diuretics) 22,356 East Asian ancestry cases, 156,370 East Asian ancestry controls NA Illumina [13134967] (imputed) 1 Diuretic use measurement http://www.ebi.ac.uk/efo/EFO_0009928 GCST90018765 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (beta blocking agents) 20,367 East Asian ancestry cases, 158,359 East Asian ancestry controls NA Illumina [13134967] (imputed) 8 Beta blocking agent use measurement http://www.ebi.ac.uk/efo/EFO_0009929 GCST90018766 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (calcium channel blockers) 49,327 East Asian ancestry cases, 129,399 East Asian ancestry controls NA Illumina [13134967] (imputed) 22 Calcium channel blocker use measurement http://www.ebi.ac.uk/efo/EFO_0009930 GCST90018767 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (agents acting on the renin-angiotensin system) 45,820 East Asian ancestry cases, 132,906 East Asian ancestry controls NA Illumina [13134967] (imputed) 12 Agents acting on the renin-angiotensin system use measurement http://www.ebi.ac.uk/efo/EFO_0009931 GCST90018768 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (HMG CoA reductase inhibitors) 33,295 East Asian ancestry cases, 145,431 East Asian ancestry controls NA Illumina [13429980] (imputed) 30 HMG CoA reductase inhibitor use measurement http://www.ebi.ac.uk/efo/EFO_0009932 GCST90018769 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (thyroid preparations) 3,103 East Asian ancestry cases, 175,623 East Asian ancestry controls NA Illumina [13429980] (imputed) 2 Thyroid preparation use measurement http://www.ebi.ac.uk/efo/EFO_0009933 GCST90018770 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (immunosuppressants) 3,483 East Asian ancestry cases, 175,243 East Asian ancestry controls NA Illumina [13134967] (imputed) 7 Immunosuppressant use measurement http://www.ebi.ac.uk/efo/EFO_0009934 GCST90018771 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (anti-inflammatory and antirheumatic products, non-steroids) 29,694 East Asian ancestry cases, 149,032 East Asian ancestry controls NA Illumina [13429980] (imputed) 1 Non-steroidal anti-inflammatory and antirheumatic product use measurement http://www.ebi.ac.uk/efo/EFO_0009935 GCST90018772 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (drugs affecting bone structure and mineralization) 6,143 East Asian ancestry cases, 172,583 East Asian ancestry controls NA Illumina [13429980] (imputed) 1 Drugs affecting bone structure and mineralization use measurement http://www.ebi.ac.uk/efo/EFO_0009936 GCST90018773 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (opioids) 3,566 East Asian ancestry cases, 175,160 East Asian ancestry controls NA Illumina [13429980] (imputed) 0 Opioid use measurement http://www.ebi.ac.uk/efo/EFO_0009937 GCST90018774 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (salicylic acid and derivatives) 41,461 East Asian ancestry cases, 137,265 East Asian ancestry controls NA Illumina [13429980] (imputed) 18 aspirin use measurement http://www.ebi.ac.uk/efo/EFO_0007013 GCST90018775 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (anilides) 4,421 East Asian ancestry cases, 174,305 East Asian ancestry controls NA Illumina [13429980] (imputed) 0 Anilide use measurement http://www.ebi.ac.uk/efo/EFO_0009938 GCST90018776 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (antimigraine preparations) 387 East Asian ancestry cases, 178,339 East Asian ancestry controls NA Illumina [13429980] (imputed) 1 Antimigraine preparation use measurement http://www.ebi.ac.uk/efo/EFO_0009939 GCST90018777 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (antidepressants) 3,288 East Asian ancestry cases, 175,438 East Asian ancestry controls NA Illumina [13429980] (imputed) 0 Antidepressant use measurement http://www.ebi.ac.uk/efo/EFO_0009940 GCST90018778 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (adrenergics, inhalants) 5,880 East Asian ancestry cases, 172,846 East Asian ancestry controls NA Illumina [13429980] (imputed) 2 Inhalant adrenergic use measurement http://www.ebi.ac.uk/efo/EFO_0009941 GCST90018779 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (glucocorticoids) 13,102 East Asian ancestry cases, 165,624 East Asian ancestry controls NA Illumina [13429980] (imputed) 1 Glucocorticoid use measurement http://www.ebi.ac.uk/efo/EFO_0009942 GCST90018780 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (antihistamines for systemic use) 10,163 East Asian ancestry cases, 168,563 East Asian ancestry controls NA Illumina [13429980] (imputed) 1 Antihistamine use measurement http://www.ebi.ac.uk/efo/EFO_0009943 GCST90018781 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (antiglaucoma preparations and miotics) 5,911 East Asian ancestry cases, 172,815 East Asian ancestry controls NA Illumina [13429980] (imputed) 3 Antiglaucoma preparations and miotics use measurement http://www.ebi.ac.uk/efo/EFO_0009944 GCST90018782 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Aortic aneurysm 3,230 European ancestry cases, 475,964 European ancestry controls, 1,155 East Asian ancestry cases, 173,601 East Asian ancestry controls NA Affymetrix, Illumina [25843950] (imputed) 7 aortic aneurysm http://www.ebi.ac.uk/efo/EFO_0001666 GCST90018783 Genome-wide genotyping array 653950 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Atopic dermatitis 6,224 European ancestry cases, 475,075 European ancestry controls, 4,296 East Asian ancestry cases, 163,807 East Asian ancestry controls NA Affymetrix, Illumina [25843389] (imputed) 23 atopic eczema http://www.ebi.ac.uk/efo/EFO_0000274 GCST90018784 Genome-wide genotyping array 649402 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Autoimmune hepatitis 821 European ancestry cases, 484,413 European ancestry controls, 85 East Asian ancestry cases, 166,529 East Asian ancestry controls NA Affymetrix, Illumina [25843756] (imputed) 1 Autoimmune Hepatitis http://www.ebi.ac.uk/efo/EFO_0005676 GCST90018785 Genome-wide genotyping array 651848 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Abortion 7,069 European ancestry cases, 250,492 European ancestry controls, 136 East Asian ancestry cases, 82,625 East Asian ancestry controls NA Affymetrix, Illumina [25789421] (imputed) 0 abortion http://www.ebi.ac.uk/efo/EFO_1001491 GCST90018786 Genome-wide genotyping array 340322 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Achilles tendon injury 7,746 European ancestry cases, 349,912 European ancestry controls, 312 East Asian ancestry cases, 175,979 East Asian ancestry controls NA Affymetrix, Illumina [20458085] (imputed) 0 Tendinopathy http://www.ebi.ac.uk/efo/EFO_1001434 GCST90018787 Genome-wide genotyping array 533949 2013-02-21 23267103 Desch KC 2012-12-24 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/23267103 Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association. Coagulation factor levels 3,250 European ancestry individuals, up to 212 individuals NA Illumina [723716] 7 coagulation factor measurement http://www.ebi.ac.uk/efo/EFO_0004634 GCST001793 Genome-wide genotyping array 3462 2011-01-27 21221998 Kim JJ 2011-01-09 Hum Genet www.ncbi.nlm.nih.gov/pubmed/21221998 A genome-wide association analysis reveals 1p31 and 2p13.3 as susceptibility loci for Kawasaki disease. Kawasaki disease 186 Korean ancestry child cases, 600 Korean ancestry controls 514 East Asian ancestry child cases, 1,042 East Asian ancestry controls Affymetrix [641760] 2 mucocutaneous lymph node syndrome http://www.ebi.ac.uk/efo/EFO_0004246 GCST000939 Genome-wide genotyping array 786 2009-06-16 19478329 Aston KI 2009-05-28 J Androl www.ncbi.nlm.nih.gov/pubmed/19478329 Genome-wide study of single-nucleotide polymorphisms associated with azoospermia and severe oligozoospermia. Male infertility 52 European ancestry oligozoospermic cases, 40 European ancestry non-obstructive azoospermic cases, 80 European ancestry controls NA Illumina [314776] 5 male infertility http://www.ebi.ac.uk/efo/EFO_0004248 GCST000412 Genome-wide genotyping array 172 2009-03-28 19270707 Birnbaum S 2009-03-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19270707 Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24. Orofacial clefts 224 European ancestry cases, 383 European ancestry controls 246 cases, 954 controls Illumina [521176] 2 cleft lip http://www.ebi.ac.uk/efo/EFO_0003959 GCST000353 Genome-wide genotyping array 607 2010-09-14 20675712 Reed DR 2010-07-31 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/20675712 The perception of quinine taste intensity is associated with common genetic variants in a bitter receptor cluster on chromosome 12. Bitter taste response 1,457 European ancestry individuals 73 European ancestry individuals Illumina [~ 2300000] (imputed) 1 sensory perception of bitter taste http://purl.obolibrary.org/obo/GO_0050913 GCST000746 Genome-wide genotyping array 1457 2011-09-27 21866343 Ahn MJ 2011-08-25 Hum Genet www.ncbi.nlm.nih.gov/pubmed/21866343 The 18p11.22 locus is associated with never smoker non-small cell lung cancer susceptibility in Korean populations. Non-small cell lung cancer 445 Korean ancestry cases, 497 Korean ancestry controls 396 Korean ancestry cases, 998 Korean ancestry controls Affymetrix [474503] 1 non-small cell lung carcinoma http://www.ebi.ac.uk/efo/EFO_0003060 GCST001210 Genome-wide genotyping array 942 2013-02-23 23275298 Fox ER 2012-12-28 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/23275298 Genome-wide association study of cardiac structure and systolic function in African Americans: the Candidate Gene Association Resource (CARe) study. Cardiac structure and function 6,765 African American individuals 2,468 African American individuals, 12,612 European ancestry individuals Affymetrix [~ 2500000] (imputed) 0 cardiovascular measurement http://www.ebi.ac.uk/efo/EFO_0004298 GCST001797 Genome-wide genotyping array 6765 2012-07-31 22745009 Melville SA 2012-05-15 Ann Neurol www.ncbi.nlm.nih.gov/pubmed/22745009 Multiple loci influencing hippocampal degeneration identified by genome scan. Hippocampal atrophy 1149 European ancestry Alzheimer disease cases, 336 European ancestry individuals with mild cognitive impairment, 188 European ancestry controls 419 African American Alzheimer disease cases Illumina [2131250] (imputed) 12 hippocampal atrophy http://www.ebi.ac.uk/efo/EFO_0005039 GCST001530 Genome-wide genotyping array 1673 2011-10-04 21931568 Geller F 2011-09-08 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21931568 Genome-wide association study identifies four loci associated with eruption of permanent teeth. Permanent tooth development 5,088 European ancestry females 2,994 European ancestry individuals, 161 individuals Illumina [521741] 4 tooth eruption http://purl.obolibrary.org/obo/GO_0044691 GCST001221 Genome-wide genotyping array 5088 2008-06-16 18198356 Hakonarson H 2008-01-15 Diabetes www.ncbi.nlm.nih.gov/pubmed/18198356 A novel susceptibility locus for type 1 diabetes on Chr12q13 identified by a genome-wide association study. Type 1 diabetes 467 European ancestry trios, 561 European ancestry cases, 1,143 European ancestry controls 946 European ancestry cases and 1,098 European ancestry controls from 549 families, 364 European ancestry trios Illumina [543071] 1 type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001359 GCST000141 Genome-wide genotyping array 2171 2008-06-11 17362836 Schymick JC 2007-02-20 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/17362836 Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data. Amyotrophic lateral sclerosis 276 European ancestry cases, 271 European ancestry controls NA Illumina [549062] 6 amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0000253 GCST000013 Genome-wide genotyping array 547 2008-06-16 18372905 Tomlinson IP 2008-03-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18372905 A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Colorectal cancer 922 European ancestry cases, 927 European ancestry controls 17,089 European ancestry cases, 16,862 European ancestry controls, 783 cases, 664 controls Illumina [547647] 5 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST000169 Genome-wide genotyping array 1849 2008-07-22 17223258 Spinola M 2007-01-16 Cancer Lett www.ncbi.nlm.nih.gov/pubmed/17223258 Genome-wide single nucleotide polymorphism analysis of lung cancer risk detects the KLF6 gene. Lung cancer 338 European ancestry lung adenocarcinoma cases, 335 European ancestry controls 265 European ancestry non-small cell lung carcinoma cases, 356 European ancestry controls Affymetrix [~ 116204] 0 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST000011 Genome-wide genotyping array 673 2009-02-27 19116933 Hinks A 2009-01-01 Arthritis Rheum www.ncbi.nlm.nih.gov/pubmed/19116933 Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis. Arthritis (juvenile idiopathic) 279 European ancestry cases, 184 European ancestry controls up to 654 European ancestry cases, 2,024 European ancestry controls Affymetrix [88862] 1 juvenile idiopathic arthritis http://www.ebi.ac.uk/efo/EFO_0002609 GCST000309 Genome-wide genotyping array 463 2009-06-22 19503597 Kolz M 2009-06-05 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/19503597 Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. Uric acid levels 12,328 European ancestry males, 15,813 European ancestry females NA Affymetrix, Illumina [2493963] (imputed) 11 uric acid measurement http://www.ebi.ac.uk/efo/EFO_0004761 GCST000418 Genome-wide genotyping array 28141 2008-09-12 18758464 Kugathasan S 2008-08-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18758464 Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease. Inflammatory bowel disease 1,011 European ancestry cases, 4,250 European ancestry controls 1,922 European ancestry cases, 14,124 European ancestry controls Illumina [NR] 6 inflammatory bowel disease http://www.ebi.ac.uk/efo/EFO_0003767 GCST000225 Genome-wide genotyping array 5261 2008-09-03 18846228 Weidinger S 2008-08-22 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/18846228 Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus. IgE levels 1,530 European ancesrty individuals 9,769 European ancestry individuals Affymetrix [353569] 2 serum IgE measurement http://www.ebi.ac.uk/efo/EFO_0004579 GCST000222 Genome-wide genotyping array 1530 2010-09-22 20713499 Huang J 2010-08-16 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/20713499 Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression. Schizophrenia, bipolar disorder and depression (combined) 402 European ancestry schizophrenia cases, 1,021 European ancestry bipolar I cases, 493 European ancestry bipolar II cases, 1,210 European ancestry MDD cases, 1,060 European ancestry controls NA Affymetrix, Perlegen [1574154] (imputed) 5 unipolar depression, mental or behavioural disorder, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0003761, http://www.ebi.ac.uk/efo/EFO_0000677, http://www.ebi.ac.uk/efo/EFO_0000289 GCST000774 Genome-wide genotyping array 4186 2011-01-08 21113153 van der Zanden LF 2010-11-28 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21113153 Common variants in DGKK are strongly associated with risk of hypospadias. Hypospadias 436 European ancestry cases, 494 European ancestry controls 133 European ancestry cases and their parents, 266 European ancestry cases, 402 European ancestry controls Affymetrix [574400] 1 Familial hypospadias http://www.orpha.net/ORDO/Orphanet_440 GCST000888 Genome-wide genotyping array 930 2009-09-28 19727025 De Moor MH 2009-09-02 Med Sci Sports Exerc www.ncbi.nlm.nih.gov/pubmed/19727025 Genome-wide association study of exercise behavior in Dutch and American adults. Leisure-time exercise behaviour 2,622 European ancestry individuals NA Affymetrix, Perlegen [~ 1600000] (imputed) 3 exercise http://www.ebi.ac.uk/efo/EFO_0000483 GCST000474 Genome-wide genotyping array 2622 2008-09-12 18711365 Ferreira MA 2008-08-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18711365 Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Bipolar disorder 4,387 European ancestry cases, 6,209 European ancestry controls NA Affymetrix [1769948] (imputed) 21 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST000220 Genome-wide genotyping array 10596 2009-09-28 17846124 Hayes MG 2007-09-10 Diabetes www.ncbi.nlm.nih.gov/pubmed/17846124 Identification of type 2 diabetes genes in Mexican Americans through genome-wide association studies. Type 2 diabetes 281 Mexican American cases, 280 Mexican American controls 1,087 European ancestry individuals, 440 Pima Indian ancestry cases, 455 Pima Indian ancestry controls, 124 Amish cases, 295 Amish controls Affymetrix [88142] 0 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST000075 Genome-wide genotyping array 561 2010-09-07 20661308 Kapur K 2010-07-22 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/20661308 Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene. Calcium levels 8,918 European ancestry individuals, 3,947 Indian Asian ancestry individuals 4,126 European ancestry individuals Affymetrix, Illumina, Perlegen [2557252] (imputed) 1 calcium measurement http://www.ebi.ac.uk/efo/EFO_0004838 GCST000736 Genome-wide genotyping array 12865 2010-09-23 20719862 Vitart V 2010-08-18 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/20719862 New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8. Central corneal thickness 1,445 European ancestry individuals 5,882 European ancestry individuals Illumina [~ 2000000] (imputed) 5 eye measurement http://www.ebi.ac.uk/efo/EFO_0004731 GCST000775 Genome-wide genotyping array 1445 2012-07-31 22678113 Cox HC 2012-06-08 Neurogenetics www.ncbi.nlm.nih.gov/pubmed/22678113 A genome-wide analysis of 'Bounty' descendants implicates several novel variants in migraine susceptibility. Migraine 76 Norfolk Island (founder or genetic isolate) cases, 209 Norfolk Island (founder or genetic isolate) controls 4,705 European ancestry cases, 21,008 European ancestry controls Illumina [544590] 0 migraine disorder http://www.ebi.ac.uk/efo/EFO_0003821 GCST001562 Genome-wide genotyping array 285 2012-07-17 22658931 Pajewski NM 2012-05-30 Vaccine www.ncbi.nlm.nih.gov/pubmed/22658931 A genome-wide association study of host genetic determinants of the antibody response to Anthrax Vaccine Adsorbed. Immune response to anthrax vaccine 726 European ancestry individuals NA Affymetrix [736996] 8 response to vaccine http://www.ebi.ac.uk/efo/EFO_0004645 GCST001547 Genome-wide genotyping array 726 2013-05-01 23364394 Lee JY 2013-01-31 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/23364394 A genome-wide association study of a coronary artery disease risk variant. Coronary heart disease 2,123 Korean ancestry cases, 3,591 Korean ancestry controls 3,052 Japanese ancestry cases, 4,976 Japanese ancestry controls Affymetrix [521786] 5 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST001845 Genome-wide genotyping array 5714 2013-08-23 23583978 Monda KL 2013-04-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23583978 A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Body mass index 37,956 African American individuals, 1,188 Nigerian ancestry individuals 27,661 African America/Afro-Caribbean individuals, 4,607 Sub-Saharan African ancestry individuals, 123,706 European ancestry inidividuals Affymetrix, Illumina [3283202] (imputed) 7 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST001967 Genome-wide genotyping array 39144 2014-01-31 23824729 van Meurs JB 2013-07-03 Am J Clin Nutr www.ncbi.nlm.nih.gov/pubmed/23824729 Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. Homocysteine levels 44,147 European ancestry individuals NA Affymetrix, Illumina [2090256] (imputed) 18 homocysteine measurement http://www.ebi.ac.uk/efo/EFO_0004578 GCST002087 Genome-wide genotyping array 44147 2012-12-04 23017229 Voruganti VS 2012-09-24 Cytokine www.ncbi.nlm.nih.gov/pubmed/23017229 Genome-wide association replicates the association of Duffy antigen receptor for chemokines (DARC) polymorphisms with serum monocyte chemoattractant protein-1 (MCP-1) levels in Hispanic children. Monocyte chemoattractant protein-1 levels 815 Hispanic children NA Illumina [NR] 5 CCL2 measurement http://www.ebi.ac.uk/efo/EFO_0004749 GCST001691 Genome-wide genotyping array 815 2013-01-29 23149075 Aslibekyan S 2012-11-10 Nutr Metab Cardiovasc Dis www.ncbi.nlm.nih.gov/pubmed/23149075 Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network. Response to fenofibrate (adiponectin levels) 793 European ancestry individuals NA Affymetrix [2543887] (imputed) 12 response to fenofibrate http://purl.obolibrary.org/obo/GO_1901557 GCST001738 Genome-wide genotyping array 793 2014-04-25 24143882 Gelernter J 2013-10-19 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/24143882 Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways. Opioid sensitivity 1,383 European ancestry cases, 996 European ancestry controls, 683 African American cases, 2,635 African American controls 2,116 European ancestry individuals, 4,496 African American individuals Illumina [988306] 3 response to opiate http://purl.obolibrary.org/obo/GO_0014072 GCST002235 Genome-wide genotyping array 5697 2020-01-09 23823483 Rhee EP 2013-07-02 Cell Metab www.ncbi.nlm.nih.gov/pubmed/23823483 A genome-wide association study of the human metabolome in a community-based cohort. Metabolite levels 2,076 European ancestry individuals NA Affymetrix [at least 2500000] (imputed) 2148 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST009391 Genome-wide genotyping array 2076 2011-07-14 21685912 Hoglinger GU 2011-06-19 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21685912 Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. Progressive supranuclear palsy 1,069 European ancestry cases, 2,958 European ancestry controls, 45 cases, 329 controls 1,051 European ancestry cases, 3,560 European ancestry controls Illumina [531451] 11 Progressive supranuclear palsy http://www.orpha.net/ORDO/Orphanet_683 GCST001116 Genome-wide genotyping array 4401 2012-08-16 22693232 Zhou J 2012-06-12 J Infect Dis www.ncbi.nlm.nih.gov/pubmed/22693232 A functional variation in CD55 increases the severity of 2009 pandemic H1N1 influenza A virus infection. Influenza (severity) 25 Chinese ancestry severe cases, 26 Chinese ancestry controls 152 Chinese ancestry severe cases, 222 Chinese ancestry controls Affymetrix [~ 1000000] 0 influenza http://www.ebi.ac.uk/efo/EFO_0007328 GCST001568 Genome-wide genotyping array 51 2010-09-11 20707712 Mosing MA 2010-08-01 Twin Res Hum Genet www.ncbi.nlm.nih.gov/pubmed/20707712 A genome-wide association study of self-rated health. Self-rated health 6,706 European individuals from 2,585 independent families NA Illumina [2380486] (imputed) 10 self rated health http://www.ebi.ac.uk/efo/EFO_0004778 GCST000747 Genome-wide genotyping array 9291 2010-12-09 20978177 Penney KL 2010-10-26 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/20978177 Genome-wide association study of prostate cancer mortality. Prostate cancer mortality 196 European ancestry lethal cases, 368 European ancestry long-term survivor cases 500 European ancestry lethal cases, 155 European ancestry long-term survivor cases Affymetrix [419613] 0 survival time, metastatic prostate cancer http://www.ebi.ac.uk/efo/EFO_0000714, http://www.ebi.ac.uk/efo/EFO_0000196 GCST000844 Genome-wide genotyping array 564 2011-04-06 21357381 Figueiredo JC 2011-02-25 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/21357381 Genotype-environment interactions in microsatellite stable/microsatellite instability-low colorectal cancer: results from a genome-wide association study. Colorectal cancer 1,191 European ancestry cases, 999 European ancestry controls 872 European ancestry cases, 810 European ancestry controls Illumina [770098] 0 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST000989 Genome-wide genotyping array 2190 2010-12-09 21062454 Li J 2010-11-09 Breast Cancer Res www.ncbi.nlm.nih.gov/pubmed/21062454 A genome-wide association scan on estrogen receptor-negative breast cancer. Breast cancer (estrogen-receptor negative) 617 European ancestry cases, 4,583 European ancestry controls 1,011 cases, 7,604 controls Illumina [285984] 0 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST000867 Genome-wide genotyping array 5200 2011-04-04 21359210 Ricci G 2011-02-16 PLoS One www.ncbi.nlm.nih.gov/pubmed/21359210 Pooled genome-wide analysis to identify novel risk loci for pediatric allergic asthma. Asthma (childhood onset) 135 European ancestry asthma child cases, 134 European ancestry rhinoconjunctivitis child cases 35 asthma child cases, 44 rhinoconjunctivitis child cases Affymetrix [~ 500000] 0 childhood onset asthma http://www.ebi.ac.uk/efo/EFO_0004591 GCST000979 Genome-wide genotyping array 269 2012-10-23 22889924 Scharf JM 2012-08-14 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/22889924 Genome-wide association study of Tourette's syndrome. Tourette syndrome 778 European ancestry cases, 4,414 European ancestry controls, 242 Ashkenazi Jewish cases, 354 Ashkenazi Jewish controls, 265 French Canadian founder cases, 196 French Canadian founder controls 211 Latin American cases, 285 Latin American controls Illumina [484295] 7 Tourette syndrome http://www.ebi.ac.uk/efo/EFO_0004895 GCST001635 Genome-wide genotyping array 6249 2012-08-14 22685421 Fan Q 2012-06-07 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22685421 Genetic variants on chromosome 1q41 influence ocular axial length and high myopia. Myopia (pathological) 2,789 Chinese ancestry individuals, 2,155 Malay ancestry individuals NA Illumina [456634] 4 pathological myopia http://www.ebi.ac.uk/efo/EFO_0004207 GCST001561 Genome-wide genotyping array 4944 2011-01-11 21139019 Walsh KM 2010-12-07 Endocr Relat Cancer www.ncbi.nlm.nih.gov/pubmed/21139019 A pilot genome-wide association study shows genomic variants enriched in the non-tumor cells of patients with well-differentiated neuroendocrine tumors of the ileum. Ileal carcinoids 239 European ancestry cases, 107 European ancestry controls NA Illumina [308330] 4 carcinoid tumor http://www.ebi.ac.uk/efo/EFO_0004243 GCST000908 Genome-wide genotyping array 346 2010-07-12 20570966 McGovern DP 2010-06-22 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/20570966 Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease. Crohn's disease 896 European ancestry cases, 3,204 European ancestry controls 1,174 European ancestry cases, 357 European ancestry controls Illumina [304825] 7 Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000384 GCST000705 Genome-wide genotyping array 4100 2011-06-18 21647738 Wu Y 2011-06-07 Inflammation www.ncbi.nlm.nih.gov/pubmed/21647738 Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment. C-reactive protein 1,709 Filipino ancestry female individuals NA Affymetrix [2073674] (imputed) 3 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST001093 Genome-wide genotyping array 1709 2010-10-15 20876420 Ingle JN 2010-09-27 J Clin Oncol www.ncbi.nlm.nih.gov/pubmed/20876420 Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors. Adverse response to aromatase inhibitors 293 cases, 585 controls NA Illumina [551395] 1 response to aromatase inhibitor http://purl.obolibrary.org/obo/GO_0061477 GCST000813 Genome-wide genotyping array 878 2011-12-17 22101970 Kho AN 2011-11-19 J Am Med Inform Assoc www.ncbi.nlm.nih.gov/pubmed/22101970 Use of diverse electronic medical record systems to identify genetic risk for type 2 diabetes within a genome-wide association study. Type 2 diabetes 2,413 European ancestry cases, 2,392 European ancestry controls, 810 African American cases, 873 African American controls NA Illumina [NR] 1 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST001326 Genome-wide genotyping array 6488 2008-08-27 19165918 Graham RR 2008-08-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19165918 Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. Systemic lupus erythematosus 431 European ancestry cases, 2,155 European ancestry controls 447 European ancestry trios, 293 trios Affymetrix [313238] 8 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST000216 Genome-wide genotyping array 2586 2008-10-14 18820697 Miyagawa T 2008-09-28 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18820697 Variant between CPT1B and CHKB associated with susceptibility to narcolepsy. Narcolepsy 222 Japanese ancestry cases, 389 Japanese ancestry controls 274 East Asian ancestry cases, 499 East Asian ancestry controls, 388 European ancestry cases, 397 European ancestry controls, 86 African American cases, 98 African American controls Affymetrix [249133] 1 narcolepsy with cataplexy http://www.ebi.ac.uk/efo/EFO_0000614 GCST000236 Genome-wide genotyping array 611 2011-10-20 21943158 Middelberg RP 2011-09-24 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/21943158 Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits. Cardiovascular disease risk factors 11,683 European ancestry individuals NA Illumina [NR] (imputed) 19 aspartate aminotransferase measurement, butyrylcholinesterase measurement, triglyceride measurement, ferritin measurement, serum gamma-glutamyl transferase measurement, low density lipoprotein cholesterol measurement, C-reactive protein measurement, uric acid measurement, high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004736, http://www.ebi.ac.uk/efo/EFO_0004571, http://www.ebi.ac.uk/efo/EFO_0004530, http://www.ebi.ac.uk/efo/EFO_0004459, http://www.ebi.ac.uk/efo/EFO_0004532, http://www.ebi.ac.uk/efo/EFO_0004611, http://www.ebi.ac.uk/efo/EFO_0004458, http://www.ebi.ac.uk/efo/EFO_0004761, http://www.ebi.ac.uk/efo/EFO_0004612 GCST001247 Genome-wide genotyping array 11683 2011-10-16 21940970 Meschia JF 2011-09-22 Stroke www.ncbi.nlm.nih.gov/pubmed/21940970 Siblings with ischemic stroke study: results of a genome-wide scan for stroke loci. Stroke 223 cases, 248 stroke-affected siblings, 84 stroke-unaffected siblings NA Illumina [NR] 0 stroke http://www.ebi.ac.uk/efo/EFO_0000712 GCST001246 Genome-wide genotyping array 555 2013-01-16 23114982 Siegert S 2012-11-02 Hum Genet www.ncbi.nlm.nih.gov/pubmed/23114982 Genome-wide investigation of gene-environment interactions in colorectal cancer. Colorectal cancer (environment interaction) 314 European ancestry cases 259 European ancestry cases, 1,002 European ancestry controls Affymetrix [4373163] (imputed) 0 smoking status measurement, colorectal cancer, alcohol consumption measurement, overweight body mass index status http://www.ebi.ac.uk/efo/EFO_0006527, http://www.ebi.ac.uk/efo/EFO_0005842, http://www.ebi.ac.uk/efo/EFO_0007878, http://www.ebi.ac.uk/efo/EFO_0005935 GCST001731 Genome-wide genotyping array 314 2013-06-21 23502781 Germain M 2013-03-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23502781 Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension. Pulmonary arterial hypertension (without BMPR2 mutations) 340 European ancestry cases, 1,068 European ancestry controls 285 cases, 457 controls Illumina [462499] 1 pulmonary arterial hypertension http://www.ebi.ac.uk/efo/EFO_0001361 GCST001908 Genome-wide genotyping array 1408 2011-10-11 21909109 Kim YJ 2011-09-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21909109 Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits. Gamma glutamyl transpeptidase 12,545 Korean ancestry individuals Up to 30,395 East Asian ancestry individuals Affymetrix [~ 2200000] (imputed) 7 serum gamma-glutamyl transferase measurement http://www.ebi.ac.uk/efo/EFO_0004532 GCST001234 Genome-wide genotyping array 12545 2011-10-11 21909109 Kim YJ 2011-09-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21909109 Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits. HDL cholesterol 12,545 Korean ancestry individuals Up to 30,395 East Asian ancestry individuals Affymetrix [~ 2200000] (imputed) 9 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST001237 Genome-wide genotyping array 12545 2011-10-11 21909109 Kim YJ 2011-09-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21909109 Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits. Metabolite levels 12,545 Korean ancestry individuals Up to 30,395 East Asian ancestry individuals Affymetrix [~ 2200000] (imputed) 18 serum albumin measurement, metabolite measurement, serum alanine aminotransferase measurement, low density lipoprotein cholesterol measurement, fasting blood glucose measurement, uric acid measurement http://www.ebi.ac.uk/efo/EFO_0004535, http://www.ebi.ac.uk/efo/EFO_0004725, http://www.ebi.ac.uk/efo/EFO_0004735, http://www.ebi.ac.uk/efo/EFO_0004611, http://www.ebi.ac.uk/efo/EFO_0004465, http://www.ebi.ac.uk/efo/EFO_0004761 GCST001233 Genome-wide genotyping array 12545 2011-10-11 21909109 Kim YJ 2011-09-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21909109 Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits. Triglycerides 12,545 Korean ancestry individuals Up to 30,395 East Asian ancestry individuals Affymetrix [~ 2200000] (imputed) 5 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST001230 Genome-wide genotyping array 12545 2011-11-26 22027810 Forstbauer LM 2011-10-26 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/22027810 Genome-wide pooling approach identifies SPATA5 as a new susceptibility locus for alopecia areata. Alopecia areata 729 European ancestry cases, 656 European ancestry controls 991 European ancestry cases, 2,021 European ancestry controls Illumina [487932] 0 alopecia areata http://www.ebi.ac.uk/efo/EFO_0004192 GCST001295 Genome-wide genotyping array 1385 2011-11-16 21991891 Tantisira KG 2011-09-26 N Engl J Med www.ncbi.nlm.nih.gov/pubmed/21991891 Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma. Asthma treatment response 1,169 European ancestry child and parent asthmatic cases 935 European ancestry adult asthmatic cases Illumina [534290] 0 response to glucocorticoid http://purl.obolibrary.org/obo/GO_0051384 GCST001252 Genome-wide genotyping array 1169 2013-09-07 23642732 Cox AJ 2013-04-19 Atherosclerosis www.ncbi.nlm.nih.gov/pubmed/23642732 Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study. Bilirubin levels 1,180 European ancestry individuals from ~475 families NA Affymetrix, Illumina [371951] 1 bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004570 GCST001976 Genome-wide genotyping array 1655 2012-03-09 22306652 Bellenguez C 2012-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22306652 Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Stroke 3,548 European ancestry cases, 5,972 European ancestry controls 6,594 European ancestry cases, 34,864 European ancestry controls Illumina [495851] 1 stroke http://www.ebi.ac.uk/efo/EFO_0000712 GCST001400 Genome-wide genotyping array 9520 2012-09-20 22773346 Edwards DR 2012-07-07 Age (Dordr) www.ncbi.nlm.nih.gov/pubmed/22773346 Linkage and association of successful aging to the 6q25 region in large Amish kindreds. Aging 263 Amish individuals aged 80 years or older NA Affymetrix [630309] 8 aging http://purl.obolibrary.org/obo/GO_0007568 GCST001599 Genome-wide genotyping array 343 2011-10-01 21896673 Chen D 2011-09-10 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21896673 Genome-wide association study of HPV seropositivity. HPV seropositivity 1,286 European ancestry lung cancer cases, 679 European ancestry head and neck cancer cases, 811 European ancestry kidney cancer cases, 2,035 European ancestry controls 1,307 Hispanic head and neck cancer cases, 1,037 Hispanic controls Illumina [316015] 1 HPV seropositivity http://www.ebi.ac.uk/efo/EFO_0004510 GCST001225 Genome-wide genotyping array 4811 2012-12-04 22990015 Arning A 2012-09-20 Blood www.ncbi.nlm.nih.gov/pubmed/22990015 A genome-wide association study identifies a gene network of ADAMTS genes in the predisposition to pediatric stroke. Stroke (pediatric) 270 European ancestry trios NA Illumina [334581] 4 stroke http://www.ebi.ac.uk/efo/EFO_0000712 GCST001689 Genome-wide genotyping array 270 2012-11-06 22951594 Elgazzar S 2012-09-06 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/22951594 A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor-positive breast cancer in Japanese. Breast cancer 1,086 Japanese ancestry cases, 1,816 Japanese ancestry controls 1,653 Japanese ancestry cases, 2,797 Japanese ancestry controls Illumina [453627] 2 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST001667 Genome-wide genotyping array 2902 2013-04-12 22075249 Tang WH 2011-11-10 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/22075249 Clinical and genetic association of serum ceruloplasmin with cardiovascular risk. Serum ceruloplasmin levels 2,647 European ancestry individuals 2,050 European ancestry individuals Affymetrix [2421770] (imputed) 1 serum ceruloplasmin measurement http://www.ebi.ac.uk/efo/EFO_0005139 GCST001318 Genome-wide genotyping array 2647 2012-07-19 22544366 Ellinor PT 2012-04-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22544366 Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Atrial fibrillation 6,707 European ancestry cases, 52,426 European ancestry controls 5,381 European ancestry casses, 10,030 European ancestry controls Affymetrix, Illumina [~ 2500000] (imputed) 10 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST001499 Genome-wide genotyping array 59133 2013-06-26 23518928 Liu M 2013-03-21 Mol Endocrinol www.ncbi.nlm.nih.gov/pubmed/23518928 TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression. Estradiol plasma levels (breast cancer) 700 European ancestry cases, 50 African ancestry cases, 17 Asian ancestry cases, 5 American Indian ancestry cases NA Illumina [563945] 18 estradiol measurement http://www.ebi.ac.uk/efo/EFO_0004697 GCST001914 Genome-wide genotyping array 772 2013-06-18 23471985 Jahanshad N 2013-03-05 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/23471985 Genome-wide scan of healthy human connectome discovers SPON1 gene variant influencing dementia severity. Brain connectivity 331 European ancestry individuals NA Illumina [428287] 12 brain connectivity measurement http://www.ebi.ac.uk/efo/EFO_0005210 GCST001889 Genome-wide genotyping array 331 2012-07-25 22665904 Willis JA 2012-06-04 Clin Cancer Res www.ncbi.nlm.nih.gov/pubmed/22665904 A replication study and genome-wide scan of single-nucleotide polymorphisms associated with pancreatic cancer risk and overall survival. Pancreatic cancer 252 European ancestry cases 798 European ancestry cases, 21 African American cases, 10 East Asian ancestry cases, 4 Asian Indian ancestry cases Illumina [301250] 0 pancreatic carcinoma http://www.ebi.ac.uk/efo/EFO_0002618 GCST001556 Genome-wide genotyping array 252 2009-03-01 19198610 Gudbjartsson DF 2009-02-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19198610 Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. Eosinophil counts 9,392 European ancestry individuals 12,118 European ancestry individuals, 5,212 East Asian ancestry individuals Illumina [312179] 7 eosinophil count http://www.ebi.ac.uk/efo/EFO_0004842 GCST000339 Genome-wide genotyping array 9392 2010-06-23 20528957 Oedegaard KJ 2010-06-07 Genes Brain Behav www.ncbi.nlm.nih.gov/pubmed/20528957 A genome-wide association study of bipolar disorder and comorbid migraine. Migraine in psychiatric disorder 56 European ancestry bipolar disorder cases, 699 European ancestry bipolar disorder controls 131 European ancestry attention deficit hyperactivity disorder cases, 324 European ancestry attention deficit hyperactivity disorder controls Affymetrix [724067] 0 migraine disorder http://www.ebi.ac.uk/efo/EFO_0003821 GCST000695 Genome-wide genotyping array 755 2010-06-18 20520587 Nielsen DA 2010-06-01 Psychiatr Genet www.ncbi.nlm.nih.gov/pubmed/20520587 Genome-wide association study identifies genes that may contribute to risk for developing heroin addiction. Heroin addiction 200 European ancestry cases, 150 European ancestry controls, 125 African American cases, 100 African American controls NA Affymetrix [up to 113174] 0 heroin dependence http://www.ebi.ac.uk/efo/EFO_0004240 GCST000690 Genome-wide genotyping array 575 2010-07-04 20487506 Joubert BR 2010-03-01 Genome Med www.ncbi.nlm.nih.gov/pubmed/20487506 A whole genome association study of mother-to-child transmission of HIV in Malawi. HIV (mother-to-child transmission) 100 Malawian ancestry infant cases, 126 Malawian ancestry infant controls NA Illumina [586681] 0 HIV mother to child transmission http://www.ebi.ac.uk/efo/EFO_0004595 GCST000613 Genome-wide genotyping array 226 2012-02-25 22290723 Ryu J 2012-01-30 Hum Mutat www.ncbi.nlm.nih.gov/pubmed/22290723 Association of glycosylated hemoglobin with the gene encoding CDKAL1 in the Korean Association Resource (KARE) study. Glycated hemoglobin levels 4,275 Korean ancestry individuals 3,782 Korean ancestry individuals Affymetrix [1693116] (imputed) 1 HbA1c measurement http://www.ebi.ac.uk/efo/EFO_0004541 GCST001393 Genome-wide genotyping array 4275 2009-05-05 19359809 Hiura Y 2009-04-10 Circ J www.ncbi.nlm.nih.gov/pubmed/19359809 Identification of genetic markers associated with high-density lipoprotein-cholesterol by genome-wide screening in a Japanese population: the Suita study. HDL cholesterol 900 Japanese ancestry individuals 1,810 Japanese ancestry individuals Illumina [368274] 1 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST000377 Genome-wide genotyping array 900 2009-04-14 19349984 Esparza-Gordillo J 2009-04-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19349984 A common variant on chromosome 11q13 is associated with atopic dermatitis. Atopic dermatitis 939 European ancestry cases, 975 European ancestry controls, 1,097 European ancestry individuals from 270 families 2,637 European ancestry cases, 3,957 European ancestry controls Affymetrix [342303] 1 atopic eczema http://www.ebi.ac.uk/efo/EFO_0000274 GCST000374 Genome-wide genotyping array 3281 2011-05-26 21502949 Stein JL 2011-04-19 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/21502949 Discovery and replication of dopamine-related gene effects on caudate volume in young and elderly populations (N=1198) using genome-wide search. Caudate nucleus volume 734 European ancestry individuals 464 European ancestry individuals Illumina [520459] 2 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST001045 Genome-wide genotyping array 734 2013-07-12 23565138 Trzaskowski M 2013-04-02 PLoS One www.ncbi.nlm.nih.gov/pubmed/23565138 First genome-wide association study on anxiety-related behaviours in childhood. Anxiety 2,810 European ancestry children 4,804 European ancestry children Affymetrix [~ 2500000] (imputed) 0 anxiety http://www.ebi.ac.uk/efo/EFO_0005230 GCST001948 Genome-wide genotyping array 2810 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Aortic aneurysm 1,155 East Asian ancestry cases, 173,601 East Asian ancestry controls NA Illumina [13429364] (imputed) 0 aortic aneurysm http://www.ebi.ac.uk/efo/EFO_0001666 GCST90018563 Genome-wide genotyping array 174756 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Atopic dermatitis 4,296 East Asian ancestry cases, 163,807 East Asian ancestry controls NA Illumina [13428180] (imputed) 16 atopic eczema http://www.ebi.ac.uk/efo/EFO_0000274 GCST90018564 Genome-wide genotyping array 168103 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Autoimmune hepatitis 85 East Asian ancestry cases, 166,529 East Asian ancestry controls NA Illumina [13427809] (imputed) 1 Autoimmune Hepatitis http://www.ebi.ac.uk/efo/EFO_0005676 GCST90018565 Genome-wide genotyping array 166614 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Abortion 136 East Asian ancestry cases, 82,625 East Asian ancestry controls NA Illumina [13403071] (imputed) 0 abortion http://www.ebi.ac.uk/efo/EFO_1001491 GCST90018566 Genome-wide genotyping array 82761 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Achilles tendon injury 312 East Asian ancestry cases, 175,979 East Asian ancestry controls NA Illumina [13429681] (imputed) 0 Tendinopathy http://www.ebi.ac.uk/efo/EFO_1001434 GCST90018567 Genome-wide genotyping array 176291 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Acute glomerulonephritis 443 East Asian ancestry cases, 174,345 East Asian ancestry controls NA Illumina [13429216] (imputed) 0 glomerulonephritis http://purl.obolibrary.org/obo/MONDO_0002462 GCST90018568 Genome-wide genotyping array 174788 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Acute pancreatitis 827 East Asian ancestry cases, 177,471 East Asian ancestry controls NA Illumina [13429917] (imputed) 1 pancreatitis http://www.ebi.ac.uk/efo/EFO_0000278 GCST90018569 Genome-wide genotyping array 178298 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Acute renal failure 465 East Asian ancestry cases, 174,345 East Asian ancestry controls NA Illumina [13429317] (imputed) 0 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST90018570 Genome-wide genotyping array 174810 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Allergic conjunctivitis 3,900 East Asian ancestry cases, 174,719 East Asian ancestry controls NA Illumina [13429967] (imputed) 0 conjunctivitis http://www.ebi.ac.uk/efo/EFO_0009450 GCST90018571 Genome-wide genotyping array 178619 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Allergic rhinitis 7,897 East Asian ancestry cases, 153,666 East Asian ancestry controls NA Illumina [13427369] (imputed) 0 allergic rhinitis http://www.ebi.ac.uk/efo/EFO_0005854 GCST90018572 Genome-wide genotyping array 161563 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Angina pectoris 14,007 East Asian ancestry cases, 145,158 East Asian ancestry controls NA Illumina [13426705] (imputed) 19 angina pectoris http://www.ebi.ac.uk/efo/EFO_0003913 GCST90018573 Genome-wide genotyping array 159165 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Aplastic anemia 53 East Asian ancestry cases, 174,057 East Asian ancestry controls NA Illumina [13429217] (imputed) 1 Aplastic anemia http://purl.obolibrary.org/obo/HP_0001915 GCST90018574 Genome-wide genotyping array 174110 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Asthma 13,015 East Asian ancestry cases, 162,933 East Asian ancestry controls NA Illumina [13429513] (imputed) 21 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST90018575 Genome-wide genotyping array 175948 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Atrial fibrillation/atrial flutter 4,150 East Asian ancestry cases, 155,540 East Asian ancestry controls NA Illumina [13427194] (imputed) 8 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST90018576 Genome-wide genotyping array 159690 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Back pain 1,732 East Asian ancestry cases, 176,994 East Asian ancestry controls NA Illumina [13429980] (imputed) 1 Back pain http://purl.obolibrary.org/obo/HP_0003418 GCST90018577 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Behcet's disease 78 East Asian ancestry cases, 171,966 East Asian ancestry controls NA Illumina [13428939] (imputed) 0 Behcet's syndrome http://www.ebi.ac.uk/efo/EFO_0003780 GCST90018578 Genome-wide genotyping array 172044 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Breast cancer 6,325 East Asian ancestry cases, 73,225 East Asian ancestry controls NA Illumina [13401000] (imputed) 8 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST90018579 Genome-wide genotyping array 79550 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Brain tumor 405 East Asian ancestry cases, 178,321 East Asian ancestry controls NA Illumina [13429980] (imputed) 0 brain neoplasm http://www.ebi.ac.uk/efo/EFO_0003833 GCST90018580 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Bronchiectasis 241 East Asian ancestry cases, 161,803 East Asian ancestry controls NA Illumina [13427077] (imputed) 1 bronchiectasis http://purl.obolibrary.org/obo/MONDO_0004822 GCST90018581 Genome-wide genotyping array 162044 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Bronchitis 1,465 East Asian ancestry cases, 170,000 East Asian ancestry controls NA Illumina [13428877] (imputed) 2 bronchitis http://www.ebi.ac.uk/efo/EFO_0009661 GCST90018582 Genome-wide genotyping array 171465 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Hepatic bile duct cancer 418 East Asian ancestry cases, 159,201 East Asian ancestry controls NA Illumina [13427010] (imputed) 0 cholangiocarcinoma http://www.ebi.ac.uk/efo/EFO_0005221 GCST90018583 Genome-wide genotyping array 159619 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic hepatitis B infection 2,234 East Asian ancestry cases, 169,588 East Asian ancestry controls NA Illumina [13428705] (imputed) 1 chronic hepatitis B virus infection http://www.ebi.ac.uk/efo/EFO_0004239 GCST90018584 Genome-wide genotyping array 171822 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic hepatitis C infection 7,110 East Asian ancestry cases, 169,588 East Asian ancestry controls NA Illumina [13429570] (imputed) 4 chronic hepatitis C virus infection http://www.ebi.ac.uk/efo/EFO_0004220 GCST90018585 Genome-wide genotyping array 176698 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic heart failure 10,540 East Asian ancestry cases, 168,186 East Asian ancestry controls NA Illumina [13429980] (imputed) 3 heart failure http://www.ebi.ac.uk/efo/EFO_0003144 GCST90018586 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic obstructive pulmonary disease 4,017 East Asian ancestry cases, 162,653 East Asian ancestry controls NA Illumina [13427899] (imputed) 5 chronic obstructive pulmonary disease http://www.ebi.ac.uk/efo/EFO_0000341 GCST90018587 Genome-wide genotyping array 166670 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Depression 836 East Asian ancestry cases, 177,794 East Asian ancestry controls NA Illumina [13429968] (imputed) 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90018613 Genome-wide genotyping array 178630 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Dilated cardiomyopathy 417 East Asian ancestry cases, 177,745 East Asian ancestry controls NA Illumina [13429894] (imputed) 0 dilated cardiomyopathy http://www.ebi.ac.uk/efo/EFO_0000407 GCST90018614 Genome-wide genotyping array 178162 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Diphtheria 541 East Asian ancestry cases, 170,247 East Asian ancestry controls NA Illumina [13428661] (imputed) 0 diphtheria http://www.ebi.ac.uk/efo/EFO_0005549 GCST90018615 Genome-wide genotyping array 170788 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Dysentery 411 East Asian ancestry cases, 178,071 East Asian ancestry controls NA Illumina [13429933] (imputed) 1 dysentery http://www.ebi.ac.uk/efo/EFO_1001869 GCST90018616 Genome-wide genotyping array 178482 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Ectopic pregnancy 605 East Asian ancestry cases, 82,156 East Asian ancestry controls NA Illumina [13403071] (imputed) 0 Ectopic pregnancy http://purl.obolibrary.org/obo/HP_0031456 GCST90018617 Genome-wide genotyping array 82761 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Endometrial cancer 1,200 East Asian ancestry cases, 60,614 East Asian ancestry controls NA Illumina [13381748] (imputed) 0 endometrial carcinoma http://www.ebi.ac.uk/efo/EFO_1001512 GCST90018618 Genome-wide genotyping array 61814 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Endometriosis 1,786 East Asian ancestry cases, 80,975 East Asian ancestry controls NA Illumina [13403071] (imputed) 2 endometriosis http://www.ebi.ac.uk/efo/EFO_0001065 GCST90018619 Genome-wide genotyping array 82761 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Epilepsy 2,466 East Asian ancestry cases, 175,788 East Asian ancestry controls NA Illumina [13429903] (imputed) 1 epilepsy http://www.ebi.ac.uk/efo/EFO_0000474 GCST90018620 Genome-wide genotyping array 178254 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Esophageal cancer 1,388 East Asian ancestry cases, 159,201 East Asian ancestry controls NA Illumina [13427188] (imputed) 4 esophageal carcinoma http://www.ebi.ac.uk/efo/EFO_0002916 GCST90018621 Genome-wide genotyping array 160589 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Esophageal varix 264 East Asian ancestry cases, 177,516 East Asian ancestry controls NA Illumina [13429790] (imputed) 0 esophageal varices http://www.ebi.ac.uk/efo/EFO_0009545 GCST90018622 Genome-wide genotyping array 177780 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Bell's palsy 343 East Asian ancestry cases, 178,191 East Asian ancestry controls NA Illumina [13429851] (imputed) 0 Bell's palsy http://www.ebi.ac.uk/efo/EFO_0007167 GCST90018623 Genome-wide genotyping array 178534 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Febrile seizures 574 East Asian ancestry cases, 175,272 East Asian ancestry controls NA Illumina [13429256] (imputed) 0 Seizure http://purl.obolibrary.org/obo/HP_0001250 GCST90018624 Genome-wide genotyping array 175846 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Food allergy 3,777 East Asian ancestry cases, 165,939 East Asian ancestry controls NA Illumina [13428657] (imputed) 0 food allergy measurement http://www.ebi.ac.uk/efo/EFO_0007016 GCST90018625 Genome-wide genotyping array 169716 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Gallbladder polyp 843 East Asian ancestry cases, 167,459 East Asian ancestry controls NA Illumina [13133316] (imputed) 1 polyp of gallbladder http://purl.obolibrary.org/obo/MONDO_0021416 GCST90018626 Genome-wide genotyping array 168302 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Graves' disease 2,809 East Asian ancestry cases, 172,656 East Asian ancestry controls NA Illumina [13429311] (imputed) 15 Graves disease http://www.ebi.ac.uk/efo/EFO_0004237 GCST90018627 Genome-wide genotyping array 175465 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Gastroesophageal reflux disease 948 East Asian ancestry cases, 177,516 East Asian ancestry controls NA Illumina [13429914] (imputed) 0 gastroesophageal reflux disease http://www.ebi.ac.uk/efo/EFO_0003948 GCST90018628 Genome-wide genotyping array 178464 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Gastric cancer 7,921 East Asian ancestry cases, 159,201 East Asian ancestry controls NA Illumina [13428249] (imputed) 7 gastric carcinoma http://www.ebi.ac.uk/efo/EFO_0000178 GCST90018629 Genome-wide genotyping array 167122 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Gastric polyp 1,337 East Asian ancestry cases, 158,249 East Asian ancestry controls NA Illumina [13427015] (imputed) 2 stomach polyp http://purl.obolibrary.org/obo/MONDO_0008277 GCST90018630 Genome-wide genotyping array 159586 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Gastric ulcer 12,650 East Asian ancestry cases, 161,227 East Asian ancestry controls NA Illumina [13429311] (imputed) 4 gastric ulcer http://www.ebi.ac.uk/efo/EFO_0009454 GCST90018631 Genome-wide genotyping array 173877 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Glaucoma 8,448 East Asian ancestry cases, 168,903 East Asian ancestry controls NA Illumina [13429686] (imputed) 8 glaucoma http://www.ebi.ac.uk/efo/EFO_0000516 GCST90018632 Genome-wide genotyping array 177351 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Goiter 1,127 East Asian ancestry cases, 172,656 East Asian ancestry controls NA Illumina [13429016] (imputed) 0 goiter http://www.ebi.ac.uk/efo/EFO_0004283 GCST90018633 Genome-wide genotyping array 173783 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Acute hepatitis A infection 261 East Asian ancestry cases, 166,603 East Asian ancestry controls NA Illumina [13427866] (imputed) 0 hepatitis A virus infection http://www.ebi.ac.uk/efo/EFO_0007305 GCST90018634 Genome-wide genotyping array 166864 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Hashimoto thyroiditis 537 East Asian ancestry cases, 172,656 East Asian ancestry controls NA Illumina [13428945] (imputed) 2 Hashimoto's thyroiditis http://www.ebi.ac.uk/efo/EFO_0003779 GCST90018635 Genome-wide genotyping array 173193 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Head injury 2,440 East Asian ancestry cases, 176,286 East Asian ancestry controls NA Illumina [13429980] (imputed) 0 head injury http://www.ebi.ac.uk/efo/EFO_0009505 GCST90018636 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Hearing loss, difficulty in hearing 3,400 East Asian ancestry cases, 175,326 East Asian ancestry controls NA Illumina [13429980] (imputed) 0 hearing loss http://www.ebi.ac.uk/efo/EFO_0004238 GCST90018637 Genome-wide genotyping array 178726 2008-09-15 17975299 Webster JA 2007-11-01 Neurodegener Dis www.ncbi.nlm.nih.gov/pubmed/17975299 Sorl1 as an Alzheimer's disease predisposition gene? Alzheimer's disease 664 cases, 422 controls NA Affymetrix [~ 502627] 1 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST000121 Genome-wide genotyping array 1086 2008-06-16 17435756 Rioux JD 2007-04-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/17435756 Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Crohn's disease 946 cases, 977 controls 530 trios, 353 cases, 207 controls Illumina [304413] 4 Crohn's disease http://www.ebi.ac.uk/efo/EFO_0000384 GCST000023 Genome-wide genotyping array 1923 2008-06-16 17999355 Stokowski RP 2007-10-15 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/17999355 A genomewide association study of skin pigmentation in a South Asian population. Skin pigmentation 363 South Asian ancestry low maxL* individuals, 374 South Asian ancestry high maxL* individuals 116 South Asian ancestry low maxL* individuals, 115 South Asian ancestry high maxL* individuals Perlegen [1502205] 3 skin pigmentation http://www.ebi.ac.uk/efo/EFO_0003784 GCST000114 Genome-wide genotyping array 737 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Ulcerative colitis 314 East Asian ancestry cases, 178,375 East Asian ancestry controls NA Illumina [13429945] (imputed) 1 ulcerative colitis http://www.ebi.ac.uk/efo/EFO_0000729 GCST90018713 Genome-wide genotyping array 178689 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Uterine fibroids 14,475 East Asian ancestry cases, 65,733 East Asian ancestry controls NA Illumina [13401454] (imputed) 20 uterine fibroid http://www.ebi.ac.uk/efo/EFO_0000731 GCST90018714 Genome-wide genotyping array 80208 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Urolithiasis 11,699 East Asian ancestry cases, 167,027 East Asian ancestry controls NA Illumina [13429980] (imputed) 19 urolithiasis http://purl.obolibrary.org/obo/MONDO_0024647 GCST90018715 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Urticaria 9,893 East Asian ancestry cases, 162,190 East Asian ancestry controls NA Illumina [13429081] (imputed) 2 NA NA GCST90018716 Genome-wide genotyping array 172083 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Uterine prolapse 423 East Asian ancestry cases, 82,338 East Asian ancestry controls NA Illumina [13403071] (imputed) 0 uterine prolapse http://www.ebi.ac.uk/efo/EFO_1001864 GCST90018717 Genome-wide genotyping array 82761 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Uveitis 125 East Asian ancestry cases, 174,600 East Asian ancestry controls NA Illumina [13429518] (imputed) 0 uveitis http://www.ebi.ac.uk/efo/EFO_1001231 GCST90018718 Genome-wide genotyping array 174725 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Varicose veins 474 East Asian ancestry cases, 178,252 East Asian ancestry controls NA Illumina [13429980] (imputed) 0 Varicose veins http://purl.obolibrary.org/obo/HP_0002619 GCST90018719 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Ventricular arrhythmia 1,673 East Asian ancestry cases, 155,540 East Asian ancestry controls NA Illumina [13426630] (imputed) 1 Ventricular arrhythmia http://purl.obolibrary.org/obo/HP_0004308 GCST90018720 Genome-wide genotyping array 157213 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Zoster infection 2,209 East Asian ancestry cases, 166,603 East Asian ancestry controls NA Illumina [13428120] (imputed) 1 Herpes Zoster http://www.ebi.ac.uk/efo/EFO_0006510 GCST90018721 Genome-wide genotyping array 168812 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Serum alkaline phosphatase levels 118,886 East Asian ancestry individuals NA Illumina [13474352] (imputed) 37 alkaline phosphatase measurement http://www.ebi.ac.uk/efo/EFO_0004533 GCST90018722 Genome-wide genotyping array 118886 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Alanine aminotransferase levels 150,545 East Asian ancestry individuals NA Illumina [13478866] (imputed) 32 serum alanine aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004735 GCST90018723 Genome-wide genotyping array 150545 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Aspartate aminotransferase levels 150,068 East Asian ancestry individuals NA Illumina [13478956] (imputed) 32 aspartate aminotransferase measurement http://www.ebi.ac.uk/efo/EFO_0004736 GCST90018724 Genome-wide genotyping array 150068 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Serum albumin levels 120,539 East Asian ancestry individuals NA Illumina [13474682] (imputed) 26 serum albumin measurement http://www.ebi.ac.uk/efo/EFO_0004535 GCST90018725 Genome-wide genotyping array 120539 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Basophil count 91,908 East Asian ancestry individuals NA Illumina [13469940] (imputed) 37 basophil count http://www.ebi.ac.uk/efo/EFO_0005090 GCST90018726 Genome-wide genotyping array 91908 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Body mass index 163,835 East Asian ancestry individuals NA Illumina [13479178] (imputed) 89 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST90018727 Genome-wide genotyping array 163835 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Blood urea nitrogen levels 148,767 East Asian ancestry individuals NA Illumina [13478792] (imputed) 44 blood urea nitrogen measurement http://www.ebi.ac.uk/efo/EFO_0004741 GCST90018728 Genome-wide genotyping array 148767 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Weight 165,419 East Asian ancestry individuals NA Illumina [13479924] (imputed) 157 body weight http://www.ebi.ac.uk/efo/EFO_0004338 GCST90018729 Genome-wide genotyping array 165419 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. C-reactive protein 83,025 East Asian ancestry individuals NA Illumina [13470202] (imputed) 5 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST90018730 Genome-wide genotyping array 83025 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Calcium levels 83,980 East Asian ancestry individuals NA Illumina [13468899] (imputed) 15 calcium measurement http://www.ebi.ac.uk/efo/EFO_0004838 GCST90018731 Genome-wide genotyping array 83980 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Diastolic blood pressure 145,515 East Asian ancestry individuals NA Illumina [13477770] (imputed) 24 diastolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006336 GCST90018732 Genome-wide genotyping array 145515 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Eosinophil counts 93,063 East Asian ancestry individuals NA Illumina [13470073] (imputed) 38 eosinophil count http://www.ebi.ac.uk/efo/EFO_0004842 GCST90018733 Genome-wide genotyping array 93063 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Gamma glutamyl transpeptidase 133,471 East Asian ancestry individuals NA Illumina [13476165] (imputed) 52 serum gamma-glutamyl transferase measurement http://www.ebi.ac.uk/efo/EFO_0004532 GCST90018734 Genome-wide genotyping array 133471 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Glucose levels 133,336 East Asian ancestry individuals NA Illumina [13476509] (imputed) 17 glucose measurement http://www.ebi.ac.uk/efo/EFO_0004468 GCST90018735 Genome-wide genotyping array 133336 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. HDL cholesterol 74,970 East Asian ancestry individuals NA Illumina [13465896] (imputed) 41 high density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004612 GCST90018736 Genome-wide genotyping array 74970 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Hemoglobin 152,447 East Asian ancestry individuals NA Illumina [13478948] (imputed) 45 hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004509 GCST90018737 Genome-wide genotyping array 152447 2008-07-22 18317468 Sklar P 2008-03-04 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/18317468 Whole-genome association study of bipolar disorder. Bipolar disorder 1,461 European ancestry cases, 2,008 European ancestry controls 409 European ancestry trios from 256 families, 365 European ancestry cases, 351 European ancestry controls Affymetrix [372193] 0 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST000158 Genome-wide genotyping array 3469 2011-01-12 21123754 Kim S 2010-12-01 Neurology www.ncbi.nlm.nih.gov/pubmed/21123754 Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort. Alzheimer's disease biomarkers 96 European ancestry Alzheimer disease cases, 176 European ancestry individuals with mild cognitive impairment, 102 European ancestry controls NA Illumina [322557] 7 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST000900 Genome-wide genotyping array 374 2013-09-21 20117844 Brynedal B 2010-02-01 J Neuroimmunol www.ncbi.nlm.nih.gov/pubmed/20117844 MGAT5 alters the severity of multiple sclerosis. Multiple sclerosis (severity) 1,040 European ancestry cases 873 European ancestry cases Affymetrix [105035] 1 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST000577 Genome-wide genotyping array 1040 2015-05-15 21347284 Smith JG 2011-02-10 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21347284 Genome-wide association studies of the PR interval in African Americans. PR interval 6,247 African American individuals 2,022 African American individuals Affymetrix [2801419] (imputed) 5 PR interval http://www.ebi.ac.uk/efo/EFO_0004462 GCST000971 Genome-wide genotyping array 6247 2013-10-18 20308991 Kim S 2010-03-23 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/20308991 Integrative genome-wide association analysis of cytoarchitectural abnormalities in the prefrontal cortex of psychiatric disorders. Brain cytoarchitecture 14 European ancestry bipolar cases, 15 European ancestry depression cases, 13 European ancestry schizophrenia cases, 14 European ancestry controls NA Affymetrix [309531] 2 prefrontal cortex cytoarchtiectural measurement http://www.ebi.ac.uk/efo/EFO_0006913 GCST000636 Genome-wide genotyping array 56 2010-02-08 20081857 Saxena R 2010-01-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20081857 Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Two-hour glucose challenge 15,234 individuals up to 30,620 European ancestry individuals Affymetrix, Illumina [NR] 5 glucose tolerance test http://www.ebi.ac.uk/efo/EFO_0004307 GCST000569 Genome-wide genotyping array 15234 2010-02-28 20101243 Petersen GM 2010-01-24 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20101243 A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33. Pancreatic cancer 3,851 European, Chinese and other ancestry cases, 3,934 European, Chinese and other ancestry controls NA Illumina [551766] 3 pancreatic carcinoma http://www.ebi.ac.uk/efo/EFO_0002618 GCST000574 Genome-wide genotyping array 7785 2009-07-24 19581569 Treutlein J 2009-07-01 Arch Gen Psychiatry www.ncbi.nlm.nih.gov/pubmed/19581569 Genome-wide association study of alcohol dependence. Alcohol dependence 476 European ancestry cases, 1,358 European ancestry controls 1,024 European ancestry cases, 996 European ancestry controls Illumina [524396] 6 alcohol dependence http://www.ebi.ac.uk/efo/EFO_0003829 GCST000432 Genome-wide genotyping array 1834 2010-02-10 20096396 Kung AW 2010-01-20 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/20096396 Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies. Bone mineral density 785 Han Chinese ancestry extreme high and low BMD female individuals 264 Han Chinese ancestry High BMD individuals, 456 Han Chinese ancestry Low BMD individuals, 3,465 Han Chinese ancestry individuals, 13,913 European ancestry individuals Illumina [488853] 1 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST000572 Genome-wide genotyping array 785 2012-03-17 22367966 Lin X 2012-02-24 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22367966 Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men. Vitamin B12 levels 1,999 Han Chinese ancestry individuals 1,496 Chinese ancestry individuals Illumina [1940245] (imputed) 6 vitamin B12 measurement http://www.ebi.ac.uk/efo/EFO_0004620 GCST001424 Genome-wide genotyping array 1999 2009-06-01 19430480 Barrett JC 2009-05-10 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19430480 Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. Type 1 diabetes 7,514 European ancestry cases, 9,045 European ancestry controls 4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families Affymetrix, Illumina [841622] (imputed) 38 type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001359 GCST000392 Genome-wide genotyping array 16559 2011-01-14 21211798 Yamada Y 2010-12-15 Atherosclerosis www.ncbi.nlm.nih.gov/pubmed/21211798 Association of a polymorphism of BTN2A1 with myocardial infarction in East Asian populations. Myocardial infarction 134 Japanese ancestry cases, 137 Japanese ancestry controls 3,954 East Asian ancestry cases, 13,222 East Asian ancestry controls Affymetrix [~ 500000] 0 myocardial infarction http://www.ebi.ac.uk/efo/EFO_0000612 GCST000920 Genome-wide genotyping array 271 2011-04-06 21357676 Sulem P 2011-02-28 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21357676 Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption. Coffee consumption 5,840 European ancestry individuals, 771 Sorbian (founder/genetic isolate) individuals 4,050 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 2 coffee consumption http://www.ebi.ac.uk/efo/EFO_0004330 GCST000992 Genome-wide genotyping array 6611 2009-01-21 19148276 Tanaka T 2009-01-16 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/19148276 Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study. Polyunsaturated fatty acid levels 1,075 European ancestry individuals 1,076 European ancestry individuals Illumina [495343] 0 lipid measurement http://www.ebi.ac.uk/efo/EFO_0004529 GCST000316 Genome-wide genotyping array 1075 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Carpal tunnel syndrome 18,855 European ancestry cases, 461,346 European ancestry controls, 192 East Asian ancestry cases, 178,534 East Asian ancestry controls NA Affymetrix, Illumina [25844227] (imputed) 16 carpal tunnel syndrome http://www.ebi.ac.uk/efo/EFO_0004143 GCST90018813 Genome-wide genotyping array 658927 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Cataracts 39,519 European ancestry cases, 452,358 European ancestry controls, 38,194 East Asian ancestry cases, 140,532 East Asian ancestry controls NA Affymetrix, Illumina [25845331] (imputed) 32 cataract http://www.ebi.ac.uk/efo/EFO_0001059 GCST90018814 Genome-wide genotyping array 670603 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Cerebral aneurysm 945 European ancestry cases, 472,738 European ancestry controls, 3,132 East Asian ancestry cases, 152,022 East Asian ancestry controls NA Affymetrix, Illumina [25841674] (imputed) 6 brain aneurysm http://www.ebi.ac.uk/efo/EFO_0003870 GCST90018815 Genome-wide genotyping array 628837 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Unruptured cerebral aneurysm 945 European ancestry cases, 472,738 European ancestry controls, 91 East Asian ancestry cases, 152,022 East Asian ancestry controls NA Affymetrix, Illumina [25841390] (imputed) 2 brain aneurysm http://www.ebi.ac.uk/efo/EFO_0003870 GCST90018816 Genome-wide genotyping array 625796 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Cervical cancer 909 European ancestry cases, 238,249 European ancestry controls, 967 East Asian ancestry cases, 60,614 East Asian ancestry controls NA Affymetrix, Illumina [25777760] (imputed) 1 cervical carcinoma http://www.ebi.ac.uk/efo/EFO_0001061 GCST90018817 Genome-wide genotyping array 300739 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Cholecystitis 9,820 European ancestry cases, 461,431 European ancestry controls, 1,860 East Asian ancestry cases, 168,253 East Asian ancestry controls NA Affymetrix, Illumina [25842273] (imputed) 13 Cholecystitis http://purl.obolibrary.org/obo/HP_0001082 GCST90018818 Genome-wide genotyping array 641364 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Cholelithiasis 26,122 European ancestry cases, 461,431 European ancestry controls, 9,305 East Asian ancestry cases, 168,253 East Asian ancestry controls NA Affymetrix, Illumina [25844936] (imputed) 51 cholelithiasis http://www.ebi.ac.uk/efo/EFO_0004799 GCST90018819 Genome-wide genotyping array 665111 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic glomerulonephritis 566 European ancestry cases, 475,255 European ancestry controls, 210 East Asian ancestry cases, 174,345 East Asian ancestry controls NA Affymetrix, Illumina [25844108] (imputed) 2 glomerulonephritis http://purl.obolibrary.org/obo/MONDO_0002462 GCST90018820 Genome-wide genotyping array 650376 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic pancreatitis 1,424 European ancestry cases, 476,104 European ancestry controls, 457 East Asian ancestry cases, 177,471 East Asian ancestry controls NA Affymetrix, Illumina [25843262] (imputed) 4 pancreatitis http://www.ebi.ac.uk/efo/EFO_0000278 GCST90018821 Genome-wide genotyping array 655456 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic renal failure 8,287 European ancestry cases, 474,571 European ancestry controls, 2,117 East Asian ancestry cases, 174,345 East Asian ancestry controls NA Affymetrix, Illumina [25844740] (imputed) 2 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST90018822 Genome-wide genotyping array 659320 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic sinusitis 7,529 European ancestry cases, 444,966 European ancestry controls, 4,617 East Asian ancestry cases, 152,226 East Asian ancestry controls NA Affymetrix, Illumina [25838895] (imputed) 6 chronic rhinosinusitis http://www.ebi.ac.uk/efo/EFO_1000024 GCST90018823 Genome-wide genotyping array 609338 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic bronchitis 10,159 European ancestry cases, 440,263 European ancestry controls, 271 East Asian ancestry cases, 161,803 East Asian ancestry controls NA Affymetrix, Illumina [25840074] (imputed) 4 chronic bronchitis http://www.ebi.ac.uk/efo/EFO_0006505 GCST90018824 Genome-wide genotyping array 612496 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic gastritis 3,645 European ancestry cases, 441,451 European ancestry controls, 744 East Asian ancestry cases, 177,982 East Asian ancestry controls NA Affymetrix, Illumina [25841562] (imputed) 0 chronic gastritis http://www.ebi.ac.uk/efo/EFO_0000337 GCST90018825 Genome-wide genotyping array 623822 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Cirrhosis 122 European ancestry cases, 347,284 European ancestry controls, 2,551 East Asian ancestry cases, 176,175 East Asian ancestry controls NA Affymetrix, Illumina [20457790] (imputed) 4 cirrhosis of liver http://www.ebi.ac.uk/efo/EFO_0001422 GCST90018826 Genome-wide genotyping array 526132 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Colon polyp 22,049 European ancestry cases, 332,368 European ancestry controls, 4,768 East Asian ancestry cases, 166,052 East Asian ancestry controls NA Affymetrix, Illumina [20457468] (imputed) 37 polyp of colon http://purl.obolibrary.org/obo/MONDO_0021400 GCST90018827 Genome-wide genotyping array 525237 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Compression fracture 1,796 European ancestry cases, 335,983 European ancestry controls, 2,856 East Asian ancestry cases, 175,870 East Asian ancestry controls NA Affymetrix, Illumina [20457262] (imputed) 0 bone fracture http://www.ebi.ac.uk/efo/EFO_0003931 GCST90018828 Genome-wide genotyping array 516505 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Constipation 15,902 European ancestry cases, 395,721 European ancestry controls, 397 East Asian ancestry cases, 176,232 East Asian ancestry controls NA Affymetrix, Illumina [25839155] (imputed) 2 Constipation http://purl.obolibrary.org/obo/HP_0002019 GCST90018829 Genome-wide genotyping array 588252 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Contact dermatitis 3,691 European ancestry cases, 475,075 European ancestry controls, 247 East Asian ancestry cases, 161,777 East Asian ancestry controls NA Affymetrix, Illumina [25842533] (imputed) 1 contact dermatitis http://www.ebi.ac.uk/efo/EFO_0005319 GCST90018830 Genome-wide genotyping array 640790 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Cystitis 4,921 European ancestry cases, 450,694 European ancestry controls, 1,665 East Asian ancestry cases, 175,288 East Asian ancestry controls NA Affymetrix, Illumina [25842667] (imputed) 2 cystitis http://www.ebi.ac.uk/efo/EFO_1000025 GCST90018831 Genome-wide genotyping array 632568 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Diabetic nephropathy 1,032 European ancestry cases, 451,248 European ancestry controls, 220 East Asian ancestry cases, 132,764 East Asian ancestry controls NA Affymetrix, Illumina [25836444] (imputed) 1 diabetic nephropathy http://www.ebi.ac.uk/efo/EFO_0000401 GCST90018832 Genome-wide genotyping array 585264 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Depression 13,559 European ancestry cases, 435,855 European ancestry controls, 836 East Asian ancestry cases, 177,794 East Asian ancestry controls NA Affymetrix, Illumina [25842841] (imputed) 1 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST90018833 Genome-wide genotyping array 628044 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Dilated cardiomyopathy 1,444 European ancestry cases, 353,937 European ancestry controls, 417 East Asian ancestry cases, 177,745 East Asian ancestry controls NA Affymetrix, Illumina [20458130] (imputed) 0 dilated cardiomyopathy http://www.ebi.ac.uk/efo/EFO_0000407 GCST90018834 Genome-wide genotyping array 533543 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Diphtheria 12,431 European ancestry cases, 341,584 European ancestry controls, 541 East Asian ancestry cases, 170,247 East Asian ancestry controls NA Affymetrix, Illumina [20457312] (imputed) 0 diphtheria http://www.ebi.ac.uk/efo/EFO_0005549 GCST90018835 Genome-wide genotyping array 524803 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Dysentery 2,733 European ancestry cases, 346,689 European ancestry controls, 411 East Asian ancestry cases, 178,071 East Asian ancestry controls NA Affymetrix, Illumina [20457834] (imputed) 2 dysentery http://www.ebi.ac.uk/efo/EFO_1001869 GCST90018836 Genome-wide genotyping array 527904 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Ectopic pregnancy 1,514 European ancestry cases, 250,492 European ancestry controls, 605 East Asian ancestry cases, 82,156 East Asian ancestry controls NA Affymetrix, Illumina [25786799] (imputed) 0 Ectopic pregnancy http://purl.obolibrary.org/obo/HP_0031456 GCST90018837 Genome-wide genotyping array 334767 2012-03-10 22327514 Postel-Vinay S 2012-02-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22327514 Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma. Ewing sarcoma Up to 427 European ancestry cases, up to 4,352 European ancestry controls 661 European ancestry cases, 1,299 European ancestry controls NR [286966] 3 Ewing sarcoma http://www.ebi.ac.uk/efo/EFO_0000174 GCST001407 Genome-wide genotyping array 4779 2013-09-26 23652523 Mayerle J 2013-05-08 JAMA www.ncbi.nlm.nih.gov/pubmed/23652523 Identification of genetic loci associated with Helicobacter pylori serologic status. Helicobacter pylori serologic status 2,623 European ancestry high titer cases, 7,862 European ancestry low or no titer controls NA Affymetrix, Illumina [~ 2500000] (imputed) 2 anti-Helicobacter pylori serum IgG measurement http://www.ebi.ac.uk/efo/EFO_0005247 GCST002014 Genome-wide genotyping array 10485 2012-03-17 22368281 Deshmukh HA 2012-02-24 J Lipid Res www.ncbi.nlm.nih.gov/pubmed/22368281 Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a). Response to statin therapy 2,702 European ancestry individuals 2,550 European ancestry individuals Illumina, Perlegen [NR] (imputed) 1 response to statin http://purl.obolibrary.org/obo/GO_0036273 GCST001425 Genome-wide genotyping array 2702 2012-06-18 22513714 Shin J 2012-04-19 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/22513714 Genetic architecture for susceptibility to gout in the KARE cohort study. Gout 520 Korean ancestry cases, 8,314 Korean ancestry controls NA Affymetrix [NR] (imputed) 0 gout http://www.ebi.ac.uk/efo/EFO_0004274 GCST001488 Genome-wide genotyping array 8834 2012-01-19 22205951 Kerner B 2011-12-21 PLoS One www.ncbi.nlm.nih.gov/pubmed/22205951 Genome-wide association study in bipolar patients stratified by co-morbidity. Bipolar disorder 1,000 European ancestry cases, 1,034 European ancestry controls NA Affymetrix [728331] 3 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST001359 Genome-wide genotyping array 2034 2013-11-20 23720494 Evans DM 2013-05-29 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23720494 Genome-wide association study identifies loci affecting blood copper, selenium and zinc. Blood trace element (Se levels) 5477 European ancestry individuals NA Illumina [> 2500000] (imputed) 10 serum selenium measurement http://www.ebi.ac.uk/efo/EFO_0005266 GCST002039 Genome-wide genotyping array 5477 2013-11-20 23720494 Evans DM 2013-05-29 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23720494 Genome-wide association study identifies loci affecting blood copper, selenium and zinc. Blood trace element (Cu levels) 2,603 European ancestry individuals NA Illumina [> 2500000] (imputed) 7 serum copper measurement http://www.ebi.ac.uk/efo/EFO_0005267 GCST002041 Genome-wide genotyping array 2603 2013-11-20 23720494 Evans DM 2013-05-29 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23720494 Genome-wide association study identifies loci affecting blood copper, selenium and zinc. Blood trace element (Zn levels) 2,603 European ancestry individuals NA Illumina [> 2500000] (imputed) 11 serum zinc measurement http://www.ebi.ac.uk/efo/EFO_0005268 GCST002040 Genome-wide genotyping array 2603 2012-01-11 22116950 Schuh-Huerta SM 2011-11-24 Hum Reprod www.ncbi.nlm.nih.gov/pubmed/22116950 Genetic variants and environmental factors associated with hormonal markers of ovarian reserve in Caucasian and African American women. Ovarian reserve 232 European ancestry female individuals, 200 African American female individuals NA Affymetrix [677261] 7 ovarian reserve http://www.ebi.ac.uk/efo/EFO_0004770 GCST001330 Genome-wide genotyping array 432 2009-09-29 19734900 Rung J 2009-09-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19734900 Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. Type 2 diabetes 679 European ancestry cases, 697 European ancestry controls 5,579 European ancestry cases, 7,096 European ancestry controls Illumina [392365] 6 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST000478 Genome-wide genotyping array 1376 2010-09-17 20802479 Anttila V 2010-08-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20802479 Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1. Migraine 2,731 European ancestry cases, 10,747 European ancestry controls 3,202 European ancestry cases, 40,062 European ancestry controls Illumina [429912] 1 migraine disorder http://www.ebi.ac.uk/efo/EFO_0003821 GCST000782 Genome-wide genotyping array 13478 2011-01-06 21084426 Saad M 2010-11-17 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21084426 Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population. Parkinson's disease 1,039 European ancestry cases, 1,984 European ancestry controls 3,232 European ancestry cases, 7,064 European ancestry controls Illumina [492929] 3 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST000874 Genome-wide genotyping array 3023 2009-09-10 19723657 Spain SL 2009-09-01 Cancer Res www.ncbi.nlm.nih.gov/pubmed/19723657 Colorectal cancer risk is not associated with increased levels of homozygosity in a population from the United Kingdom. Colorectal cancer 921 European ancestry cases, 929 European ancestry controls 1,214 European ancestry cases, 1,435 European ancestry controls Illumina [486303] 0 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST000472 Genome-wide genotyping array 1850 2009-10-14 19802338 Chasman DI 2008-10-01 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/19802338 Genetic loci associated with plasma concentration of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoprotein A1, and Apolipoprotein B among 6382 white women in genome-wide analysis with replication. Lipid traits 6,382 European ancestry females 970 European ancestry individuals Illumina [314518] 0 lipid measurement http://www.ebi.ac.uk/efo/EFO_0004529 GCST000241 Genome-wide genotyping array 6382 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Rheumatic fever 390 European ancestry cases, 476,850 European ancestry controls, 152 East Asian ancestry cases, 170,247 East Asian ancestry controls NA Affymetrix, Illumina [25843898] (imputed) 0 susceptibility to rheumatic fever measurement http://www.ebi.ac.uk/efo/EFO_0008416 GCST90018913 Genome-wide genotyping array 647639 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Ringworm 46 European ancestry cases, 354,498 European ancestry controls, 692 East Asian ancestry cases, 178,034 East Asian ancestry controls NA Affymetrix, Illumina [20458126] (imputed) 1 tinea http://www.ebi.ac.uk/efo/EFO_0007510 GCST90018914 Genome-wide genotyping array 533270 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Stable angina pectoris 17,894 European ancestry cases, 325,132 European ancestry controls, 18,833 East Asian ancestry cases, 146,214 East Asian ancestry controls NA Affymetrix, Illumina [20456336] (imputed) 50 angina pectoris http://www.ebi.ac.uk/efo/EFO_0003913 GCST90018915 Genome-wide genotyping array 508073 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Sleep apnea syndrome 13,818 European ancestry cases, 463,035 European ancestry controls, 473 East Asian ancestry cases, 177,864 East Asian ancestry controls NA Affymetrix, Illumina [25843213] (imputed) 2 sleep apnea http://www.ebi.ac.uk/efo/EFO_0003877 GCST90018916 Genome-wide genotyping array 655190 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Systemic lupus erythematosus 647 European ancestry cases, 482,264 European ancestry controls, 317 East Asian ancestry cases, 175,937 East Asian ancestry controls NA Affymetrix, Illumina [25844568] (imputed) 4 systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0002690 GCST90018917 Genome-wide genotyping array 659165 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Sarcoidosis 1,718 European ancestry cases, 484,955 European ancestry controls, 220 East Asian ancestry cases, 177,667 East Asian ancestry controls NA Affymetrix, Illumina [25845061] (imputed) 5 Sarcoidosis http://www.orpha.net/ORDO/Orphanet_797 GCST90018918 Genome-wide genotyping array 664560 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Schizophrenia 6,334 European ancestry cases, 445,120 European ancestry controls, 99 East Asian ancestry cases, 177,794 East Asian ancestry controls NA Affymetrix, Illumina [25843027] (imputed) 1 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST90018919 Genome-wide genotyping array 629347 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Sjögren's syndrome 1,296 European ancestry cases, 482,717 European ancestry controls, 303 East Asian ancestry cases, 175,599 East Asian ancestry controls NA Affymetrix, Illumina [25844664] (imputed) 3 Sjogren syndrome http://www.ebi.ac.uk/efo/EFO_0000699 GCST90018920 Genome-wide genotyping array 659915 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Skin cancer 25,928 European ancestry cases, 466,275 European ancestry controls, 154 East Asian ancestry cases, 178,572 East Asian ancestry controls NA Affymetrix, Illumina [25845421] (imputed) 50 skin neoplasm http://www.ebi.ac.uk/efo/EFO_0004198 GCST90018921 Genome-wide genotyping array 670929 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Spinal canal stenosis 9,660 European ancestry cases, 445,127 European ancestry controls, 661 East Asian ancestry cases, 178,065 East Asian ancestry controls NA Affymetrix, Illumina [25840105] (imputed) 11 spinal stenosis http://www.ebi.ac.uk/efo/EFO_0007490 GCST90018922 Genome-wide genotyping array 633513 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Subarachnoid hemorrhage 1,693 European ancestry cases, 471,562 European ancestry controls, 1,203 East Asian ancestry cases, 152,022 East Asian ancestry controls NA Affymetrix, Illumina [25841499] (imputed) 1 subarachnoid hemorrhage http://www.ebi.ac.uk/efo/EFO_0000713 GCST90018923 Genome-wide genotyping array 626480 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Substance dependence 868 European ancestry cases, 482,988 European ancestry controls, 118 East Asian ancestry cases, 178,608 East Asian ancestry controls NA Affymetrix, Illumina [25844850] (imputed) 1 drug dependence http://www.ebi.ac.uk/efo/EFO_0003890 GCST90018924 Genome-wide genotyping array 662582 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Type 1 diabetes 6,447 European ancestry cases, 451,248 European ancestry controls, 1,219 East Asian ancestry cases, 132,032 East Asian ancestry controls NA Affymetrix, Illumina [25837106] (imputed) 14 type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001359 GCST90018925 Genome-wide genotyping array 590946 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Type 2 diabetes 38,841 European ancestry cases, 451,248 European ancestry controls, 45,383 East Asian ancestry cases, 132,032 East Asian ancestry controls NA Affymetrix, Illumina [25845091] (imputed) 209 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST90018926 Genome-wide genotyping array 667504 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Stevens-Johnson syndrome 312 European ancestry cases, 483,011 European ancestry controls, 93 East Asian ancestry cases, 171,753 East Asian ancestry controls NA Affymetrix, Illumina [25844251] (imputed) 2 Stevens-Johnson syndrome http://www.ebi.ac.uk/efo/EFO_0004276 GCST90018927 Genome-wide genotyping array 655169 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Tatto pigmentation 810 European ancestry cases, 351,023 European ancestry controls, 224 East Asian ancestry cases, 178,502 East Asian ancestry controls NA Affymetrix, Illumina [20457982] (imputed) 0 skin pigmentation http://www.ebi.ac.uk/efo/EFO_0003784 GCST90018928 Genome-wide genotyping array 530559 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Thyroid cancer 1,054 European ancestry cases, 490,920 European ancestry controls, 361 East Asian ancestry cases, 178,362 East Asian ancestry controls NA Affymetrix, Illumina [25845394] (imputed) 3 thyroid carcinoma http://www.ebi.ac.uk/efo/EFO_0002892 GCST90018929 Genome-wide genotyping array 670697 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Tonsillitis 4,712 European ancestry cases, 454,117 European ancestry controls, 420 East Asian ancestry cases, 151,846 East Asian ancestry controls NA Affymetrix, Illumina [25839836] (imputed) 0 pharyngitis http://purl.obolibrary.org/obo/MONDO_0002258 GCST90018930 Genome-wide genotyping array 611095 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Typhoid fever 2,733 European ancestry cases, 346,689 European ancestry controls, 257 East Asian ancestry cases, 178,071 East Asian ancestry controls NA Affymetrix, Illumina [20457818] (imputed) 1 typhoid fever http://www.ebi.ac.uk/efo/EFO_0006789 GCST90018931 Genome-wide genotyping array 527750 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Unstable angina pectoris 9,481 European ancestry cases, 446,987 European ancestry controls, 5,891 East Asian ancestry cases, 146,214 East Asian ancestry controls NA Affymetrix, Illumina [25840389] (imputed) 22 angina pectoris http://www.ebi.ac.uk/efo/EFO_0003913 GCST90018932 Genome-wide genotyping array 608573 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Ulcerative colitis 5,371 European ancestry cases, 412,561 European ancestry controls, 314 East Asian ancestry cases, 178,375 East Asian ancestry controls NA Affymetrix, Illumina [25840981] (imputed) 19 ulcerative colitis http://www.ebi.ac.uk/efo/EFO_0000729 GCST90018933 Genome-wide genotyping array 596621 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Uterine fibroids 21,024 European ancestry cases, 237,694 European ancestry controls, 14,475 East Asian ancestry cases, 65,733 East Asian ancestry controls NA Affymetrix, Illumina [25795146] (imputed) 53 uterine fibroid http://www.ebi.ac.uk/efo/EFO_0000731 GCST90018934 Genome-wide genotyping array 338926 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Urolithiasis 6,223 European ancestry cases, 482,123 European ancestry controls, 11,699 East Asian ancestry cases, 167,027 East Asian ancestry controls NA Affymetrix, Illumina [25845211] (imputed) 35 urolithiasis http://purl.obolibrary.org/obo/MONDO_0024647 GCST90018935 Genome-wide genotyping array 667072 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Urticaria 1,057 European ancestry cases, 482,892 European ancestry controls, 9,893 East Asian ancestry cases, 162,190 East Asian ancestry controls NA Affymetrix, Illumina [25844326] (imputed) 3 NA NA GCST90018936 Genome-wide genotyping array 656032 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Uterine prolapse 10,647 European ancestry cases, 224,175 European ancestry controls, 423 East Asian ancestry cases, 82,338 East Asian ancestry controls NA Affymetrix, Illumina [25752093] (imputed) 11 uterine prolapse http://www.ebi.ac.uk/efo/EFO_1001864 GCST90018937 Genome-wide genotyping array 317583 2013-05-31 23449627 Cousminer DL 2013-02-27 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23449627 Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. Pubertal anthropometrics up to 5,043 European ancestry males, up to 5,756 European ancestry females NA Affymetrix, Illumina [~ 2500000] (imputed) 14 puberty, height growth measurement http://www.ebi.ac.uk/efo/EFO_0001382, http://www.ebi.ac.uk/efo/EFO_0005201 GCST001876 Genome-wide genotyping array 10799 2013-05-31 23449627 Cousminer DL 2013-02-27 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23449627 Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. Pubertal anthropometrics 7,161 European ancestry males, 6,879 European ancestry females 5,133 European ancestry males, 4,577 European ancestry females Affymetrix, Illumina [~ 2500000] (imputed) 11 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST001875 Genome-wide genotyping array 14040 2008-12-09 18991354 Gretarsdottir S 2008-10-01 Ann Neurol www.ncbi.nlm.nih.gov/pubmed/18991354 Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke. Stroke (ischemic) 1,661 European ancestry cases, 10,815 European ancestry controls 4,576 European ancestry cases, 19,343 European ancestry controls Illumina [310881] 1 stroke http://www.ebi.ac.uk/efo/EFO_0000712 GCST000239 Genome-wide genotyping array 12476 2009-06-10 19456320 Ma D 2009-05-28 Ann Hum Genet www.ncbi.nlm.nih.gov/pubmed/19456320 A genome-wide association study of autism reveals a common novel risk locus at 5p14.1. Autism 1,390 European ancestry individuals from 438 families 2,390 European ancestry individuals from 457 families Illumina [775311] 1 autism http://www.ebi.ac.uk/efo/EFO_0003758 GCST000411 Genome-wide genotyping array 1828 2013-08-16 20014019 Dubinsky MC 2010-08-01 Inflamm Bowel Dis www.ncbi.nlm.nih.gov/pubmed/20014019 Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease. Response to anti-TNF alpha therapy in inflammatory bowel disease 94 pediatric cases NA Illumina [301742] 4 response to TNF antagonist http://www.ebi.ac.uk/efo/EFO_0004653 GCST000748 Genome-wide genotyping array 94 2012-08-15 22703881 Tang W 2012-06-14 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/22703881 Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease. Activated partial thromboplastin time 9,240 European ancestry individuals 2611 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 9 partial thromboplastin time http://www.ebi.ac.uk/efo/EFO_0004310 GCST001574 Genome-wide genotyping array 9240 2012-08-15 22703881 Tang W 2012-06-14 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/22703881 Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease. Prothrombin time 2,583 European ancestry individuals 986 European ancestry individuals Illumina [~ 2500000] (imputed) 2 prothrombin time measurement http://www.ebi.ac.uk/efo/EFO_0008390 GCST001573 Genome-wide genotyping array 2583 2010-09-28 20800221 Terracciano A 2010-08-25 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/20800221 Genome-wide association scan of trait depression. Depression (quantitative trait) 3,972 Sardinian individuals, 839 European ancestry individuals NA Affymetrix, Illumina [up to 2500000] (imputed) 11 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST000779 Genome-wide genotyping array 4811 2010-12-01 20953188 Ellinghaus E 2010-10-17 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20953188 Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2. Psoriasis 472 European ancestry cases, 1,146 European ancestry controls 2,668, European ancestry cases, 762 French Canadian founder population cases, 2,585 cases, 3,485 European ancestry controls, 994 French Canadian founder population controls, 2,412 controls Illumina [2339118] (imputed) 3 psoriasis http://www.ebi.ac.uk/efo/EFO_0000676 GCST000836 Genome-wide genotyping array 1618 2012-04-25 22449649 Loo SK 2012-02-28 J Am Acad Child Adolesc Psychiatry www.ncbi.nlm.nih.gov/pubmed/22449649 Genome-wide association study of intelligence: additive effects of novel brain expressed genes. Intelligence 656 European ancestry individuals from ADHD families NA Illumina [795637] 21 intelligence http://www.ebi.ac.uk/efo/EFO_0004337 GCST001428 Genome-wide genotyping array 656 2012-12-06 22993228 Williams FM 2012-09-19 Ann Rheum Dis www.ncbi.nlm.nih.gov/pubmed/22993228 Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects. Disc degeneration (lumbar) 4,683 European ancestry individuals NA Affymetrix, Illumina [2552511] (imputed) 35 lumbar disc degeneration http://www.ebi.ac.uk/efo/EFO_0004994 GCST001687 Genome-wide genotyping array 4683 2012-04-28 22456796 Imamura M 2012-03-28 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22456796 A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations. Type 2 diabetes 4,470 Japanese ancestry cases, 3,071 Japanese ancestry controls 7,605 Japanese ancestry cases, 3,534 Japanese ancestry controls NR [2229890] (imputed) 4 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST001461 Genome-wide genotyping array 7541 2012-06-18 22541561 Zhao H 2012-04-26 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/22541561 A genome-wide association study reveals that variants within the HLA region are associated with risk for nonobstructive azoospermia. Non-obstructive azoospermia 802 Han Chinese ancestry cases, 1,863 Han Chinese ancestry controls 1,424 Han Chinese ancestry cases, 2,713 Han Chinese ancestry controls Affymetrix, Illumina [912924] 1 azoospermia http://www.ebi.ac.uk/efo/EFO_0000279 GCST001494 Genome-wide genotyping array 2665 2013-07-27 23511034 Yang SK 2013-04-01 Inflamm Bowel Dis www.ncbi.nlm.nih.gov/pubmed/23511034 Genome-wide association study of ulcerative colitis in Koreans suggests extensive overlapping of genetic susceptibility with Caucasians. Ulcerative colitis 388 Korean ancestry cases, 739 Korean ancestry controls 810 Korean ancestry cases, 1709 Korean ancestry controls Illumina [581060] 1 ulcerative colitis http://www.ebi.ac.uk/efo/EFO_0000729 GCST001934 Genome-wide genotyping array 1127 2013-07-27 23511034 Yang SK 2013-04-01 Inflamm Bowel Dis www.ncbi.nlm.nih.gov/pubmed/23511034 Genome-wide association study of ulcerative colitis in Koreans suggests extensive overlapping of genetic susceptibility with Caucasians. Ulcerative colitis 388 Korean ancestry cases, 739 Korean ancestry controls 417 Korean ancestry cases, 732 Korean ancestry controls Illumina [581060] 7 ulcerative colitis http://www.ebi.ac.uk/efo/EFO_0000729 GCST001938 Genome-wide genotyping array 1127 2013-07-31 23534349 Jeff JM 2013-03-28 Ann Hum Genet www.ncbi.nlm.nih.gov/pubmed/23534349 Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans. QT interval 455 African American individuals NA Illumina [> 930000] 8 QT interval http://www.ebi.ac.uk/efo/EFO_0004682 GCST001922 Genome-wide genotyping array 455 2013-07-31 23534349 Jeff JM 2013-03-28 Ann Hum Genet www.ncbi.nlm.nih.gov/pubmed/23534349 Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans. Heart rate 455 African American individuals NA Illumina [> 930000] 5 heart rate http://www.ebi.ac.uk/efo/EFO_0004326 GCST001921 Genome-wide genotyping array 455 2013-07-31 23534349 Jeff JM 2013-03-28 Ann Hum Genet www.ncbi.nlm.nih.gov/pubmed/23534349 Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans. PR interval 455 African American individuals NA Illumina [> 930000] 9 PR interval http://www.ebi.ac.uk/efo/EFO_0004462 GCST001925 Genome-wide genotyping array 455 2013-07-31 23534349 Jeff JM 2013-03-28 Ann Hum Genet www.ncbi.nlm.nih.gov/pubmed/23534349 Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans. QRS duration 455 African American individuals NA Illumina [> 930000] 9 QRS duration http://www.ebi.ac.uk/efo/EFO_0005055 GCST001920 Genome-wide genotyping array 455 2012-08-14 22832964 David SP 2012-05-22 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/22832964 Genome-wide meta-analyses of smoking behaviors in African Americans. Smoking behavior Up to 32,389 African American individuals NA Affymetrix, Illumina [~ 2900000] (imputed) 5 smoking behavior http://www.ebi.ac.uk/efo/EFO_0004318 GCST001539 Genome-wide genotyping array 32389 2015-05-06 23575227 Urbanek M 2013-04-10 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23575227 The chromosome 3q25 genomic region is associated with measures of adiposity in newborns in a multi-ethnic genome-wide association study. Anthropometric traits in newborns 1,095 Afro-Caribbean individuals, 1,363 European ancestry individuals, 616 Mexican American individuals, 1,207 Thai ancestry individuals 2,296 European ancestry individuals Illumina [up to 3563305] (imputed) 5 anthropometric measurement http://www.ebi.ac.uk/efo/EFO_0004302 GCST001964 Genome-wide genotyping array 4281 2011-11-09 22001756 Khor CC 2011-10-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22001756 Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1. Dengue shock syndrome 2,008 Vietnamese ancestry child cases, 2,018 Vietnamese ancestry child controls 1,737 Vietnamese ancestry child cases, 2,934 Vietnamese ancestry child controls Illumina [481342] 4 Dengue Hemorrhagic Fever http://www.ebi.ac.uk/efo/EFO_0004227 GCST001278 Genome-wide genotyping array 4026 2013-09-10 23620142 Reiner AP 2013-04-24 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23620142 Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia. Circulating myeloperoxidase levels (serum) 9,305 European ancestry individuals NA Affymetrix, Illumina [2397181] 5 myeloperoxidase measurement http://www.ebi.ac.uk/efo/EFO_0005243 GCST001979 Genome-wide genotyping array 9305 2013-09-10 23620142 Reiner AP 2013-04-24 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23620142 Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia. Circulating myeloperoxidase levels (plasma) 9,260 European ancestry individuals NA Affymetrix, Illumina [2421770] 3 myeloperoxidase measurement http://www.ebi.ac.uk/efo/EFO_0005243 GCST001980 Genome-wide genotyping array 9260 2011-11-15 22006218 Yoon D 2011-10-18 Hum Genet www.ncbi.nlm.nih.gov/pubmed/22006218 Large-scale genome-wide association study of Asian population reveals genetic factors in FRMD4A and other loci influencing smoking initiation and nicotine dependence. Smoking behavior 8,842 Korean ancestry individuals 1,366 African American individuals, 671 European ancestry individuals Affymetrix [352228] 6 smoking behavior http://www.ebi.ac.uk/efo/EFO_0004318 GCST001286 Genome-wide genotyping array 8842 2011-11-04 21977987 Trompet S 2011-10-06 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/21977987 Replication of LDL GWAs hits in PROSPER/PHASE as validation for future (pharmaco)genetic analyses. LDL cholesterol 5,244 European ancestry individuals 10,754 individuals Illumina [2500000] (imputed) 0 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST001262 Genome-wide genotyping array 5244 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Acute glomerulonephritis 274 European ancestry cases, 475,255 European ancestry controls, 443 East Asian ancestry cases, 174,345 East Asian ancestry controls NA Affymetrix, Illumina [25844004] (imputed) 1 glomerulonephritis http://purl.obolibrary.org/obo/MONDO_0002462 GCST90018788 Genome-wide genotyping array 650317 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Acute pancreatitis 3,798 European ancestry cases, 476,104 European ancestry controls, 827 East Asian ancestry cases, 177,471 East Asian ancestry controls NA Affymetrix, Illumina [25843473] (imputed) 3 pancreatitis http://www.ebi.ac.uk/efo/EFO_0000278 GCST90018789 Genome-wide genotyping array 658200 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Acute renal failure 7,695 European ancestry cases, 474,571 European ancestry controls, 465 East Asian ancestry cases, 174,345 East Asian ancestry controls NA Affymetrix, Illumina [25844422] (imputed) 0 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST90018790 Genome-wide genotyping array 657076 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Allergic conjunctivitis 613 European ancestry cases, 474,657 European ancestry controls, 3,900 East Asian ancestry cases, 174,719 East Asian ancestry controls NA Affymetrix, Illumina [25843839] (imputed) 0 conjunctivitis http://www.ebi.ac.uk/efo/EFO_0009450 GCST90018791 Genome-wide genotyping array 653889 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Allergic rhinitis 4,387 European ancestry cases, 471,273 European ancestry controls, 7,897 East Asian ancestry cases, 153,666 East Asian ancestry controls NA Affymetrix, Illumina [25843170] (imputed) 1 allergic rhinitis http://www.ebi.ac.uk/efo/EFO_0005854 GCST90018792 Genome-wide genotyping array 637223 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Angina pectoris 30,025 European ancestry cases, 440,906 European ancestry controls, 14,007 East Asian ancestry cases, 145,158 East Asian ancestry controls NA Affymetrix, Illumina [25842036] (imputed) 55 angina pectoris http://www.ebi.ac.uk/efo/EFO_0003913 GCST90018793 Genome-wide genotyping array 630096 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Aplastic anemia 4,128 European ancestry cases, 469,372 European ancestry controls, 53 East Asian ancestry cases, 174,057 East Asian ancestry controls NA Affymetrix, Illumina [25844082] (imputed) 1 Aplastic anemia http://purl.obolibrary.org/obo/HP_0001915 GCST90018794 Genome-wide genotyping array 647610 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Asthma 38,369 European ancestry cases, 411,131 European ancestry controls, 13,015 East Asian ancestry cases, 162,933 East Asian ancestry controls NA Affymetrix, Illumina [25837673] (imputed) 60 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST90018795 Genome-wide genotyping array 625448 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Atrial fibrillation/atrial flutter 29,212 European ancestry cases, 400,539 European ancestry controls, 4,150 East Asian ancestry cases, 155,540 East Asian ancestry controls NA Affymetrix, Illumina [25830072] (imputed) 77 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST90018796 Genome-wide genotyping array 589441 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Back pain 22,413 European ancestry cases, 445,856 European ancestry controls, 1,732 East Asian ancestry cases, 176,994 East Asian ancestry controls NA Affymetrix, Illumina [25841286] (imputed) 3 Back pain http://purl.obolibrary.org/obo/HP_0003418 GCST90018797 Genome-wide genotyping array 646995 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Behcet's disease 27 European ancestry cases, 317,225 European ancestry controls, 78 East Asian ancestry cases, 171,966 East Asian ancestry controls NA Affymetrix, Illumina [20455535] (imputed) 0 Behcet's syndrome http://www.ebi.ac.uk/efo/EFO_0003780 GCST90018798 Genome-wide genotyping array 489296 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Breast cancer 17,389 European ancestry cases, 240,341 European ancestry controls, 6,325 East Asian ancestry cases, 73,225 East Asian ancestry controls NA Affymetrix, Illumina [25794640] (imputed) 46 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST90018799 Genome-wide genotyping array 337280 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Brain tumor 833 European ancestry cases, 490,709 European ancestry controls, 405 East Asian ancestry cases, 178,321 East Asian ancestry controls NA Affymetrix, Illumina [25845383] (imputed) 2 brain neoplasm http://www.ebi.ac.uk/efo/EFO_0003833 GCST90018800 Genome-wide genotyping array 670268 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Bronchiectasis 2,888 European ancestry cases, 440,263 European ancestry controls, 241 East Asian ancestry cases, 161,803 East Asian ancestry controls NA Affymetrix, Illumina [25839694] (imputed) 2 bronchiectasis http://purl.obolibrary.org/obo/MONDO_0004822 GCST90018801 Genome-wide genotyping array 605195 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Bronchitis 4,483 European ancestry cases, 474,818 European ancestry controls, 1,465 East Asian ancestry cases, 170,000 East Asian ancestry controls NA Affymetrix, Illumina [25844193] (imputed) 3 bronchitis http://www.ebi.ac.uk/efo/EFO_0009661 GCST90018802 Genome-wide genotyping array 650766 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Hepatic bile duct cancer 832 European ancestry cases, 475,259 European ancestry controls, 418 East Asian ancestry cases, 159,201 East Asian ancestry controls NA Affymetrix, Illumina [25843020] (imputed) 1 cholangiocarcinoma http://www.ebi.ac.uk/efo/EFO_0005221 GCST90018803 Genome-wide genotyping array 635710 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic hepatitis B infection 145 European ancestry cases, 351,740 European ancestry controls, 2,234 East Asian ancestry cases, 169,588 East Asian ancestry controls NA Affymetrix, Illumina [20457334] (imputed) 1 chronic hepatitis B virus infection http://www.ebi.ac.uk/efo/EFO_0004239 GCST90018804 Genome-wide genotyping array 523707 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic hepatitis C infection 273 European ancestry cases, 351,740 European ancestry controls, 7,110 East Asian ancestry cases, 169,588 East Asian ancestry controls NA Affymetrix, Illumina [20457788] (imputed) 4 chronic hepatitis C virus infection http://www.ebi.ac.uk/efo/EFO_0004220 GCST90018805 Genome-wide genotyping array 528711 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic heart failure 14,262 European ancestry cases, 471,898 European ancestry controls, 10,540 East Asian ancestry cases, 168,186 East Asian ancestry controls NA Affymetrix, Illumina [25844553] (imputed) 9 heart failure http://www.ebi.ac.uk/efo/EFO_0003144 GCST90018806 Genome-wide genotyping array 664886 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic obstructive pulmonary disease 13,530 European ancestry cases, 454,945 European ancestry controls, 4,017 East Asian ancestry cases, 162,653 East Asian ancestry controls NA Affymetrix, Illumina [25843162] (imputed) 13 chronic obstructive pulmonary disease http://www.ebi.ac.uk/efo/EFO_0000341 GCST90018807 Genome-wide genotyping array 635145 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Colorectal cancer 6,581 European ancestry cases, 463,421 European ancestry controls, 8,305 East Asian ancestry cases, 159,386 East Asian ancestry controls NA Affymetrix, Illumina [25843452] (imputed) 34 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST90018808 Genome-wide genotyping array 637693 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Chronic suppurative otitis media 1,108 European ancestry cases, 483,037 European ancestry controls, 2,206 East Asian ancestry cases, 176,520 East Asian ancestry controls NA Affymetrix, Illumina [25844637] (imputed) 0 suppurative otitis media http://www.ebi.ac.uk/efo/EFO_0007503 GCST90018809 Genome-wide genotyping array 662871 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Cesarian section 5,336 European ancestry cases, 237,735 European ancestry controls, 451 East Asian ancestry cases, 82,310 East Asian ancestry controls NA Affymetrix, Illumina [25770781] (imputed) 0 cesarean section http://www.ebi.ac.uk/efo/EFO_0009636 GCST90018810 Genome-wide genotyping array 325832 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Cardiac valvular disease 25,070 European ancestry cases, 440,457 European ancestry controls, 1,995 East Asian ancestry cases, 176,731 East Asian ancestry controls NA Affymetrix, Illumina [25842568] (imputed) 2 heart valve disease http://www.ebi.ac.uk/efo/EFO_0009551 GCST90018811 Genome-wide genotyping array 644253 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Cardiomegaly 3,233 European ancestry cases, 349,893 European ancestry controls, 743 East Asian ancestry cases, 177,983 East Asian ancestry controls NA Affymetrix, Illumina [20458035] (imputed) 0 cardiac hypertrophy http://www.ebi.ac.uk/efo/EFO_0002503 GCST90018812 Genome-wide genotyping array 531852 2011-10-07 21912425 Tohkin M 2011-09-13 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/21912425 A whole-genome association study of major determinants for allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients. Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN) 14 Japanese ancestry cases, 991 Japanese ancestry controls NA Illumina [890321] 1 Stevens-Johnson syndrome, toxic epidermal necrolysis http://www.ebi.ac.uk/efo/EFO_0004276, http://www.ebi.ac.uk/efo/EFO_0004775 GCST001239 Genome-wide genotyping array 1005 2012-05-16 22472174 Xiao Y 2012-04-03 Clin Cancer Res www.ncbi.nlm.nih.gov/pubmed/22472174 SSBP2 variants are associated with survival in glioblastoma patients. Glioblastoma 315 European ancestry cases 434 European ancestry cases Illumina [314635] 1 glioblastoma multiforme http://www.ebi.ac.uk/efo/EFO_0000519 GCST001470 Genome-wide genotyping array 315 2011-09-30 21876539 Amin N 2011-08-30 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/21876539 Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM. Coffee consumption 18,176 European ancestry individuals 7,929 European ancestry individuals Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) 4 coffee consumption http://www.ebi.ac.uk/efo/EFO_0004330 GCST001215 Genome-wide genotyping array 18176 2011-10-04 21912186 Smith AK 2011-09-09 Neuropsychobiology www.ncbi.nlm.nih.gov/pubmed/21912186 Convergent genomic studies identify association of GRIK2 and NPAS2 with chronic fatigue syndrome. Chronic fatigue syndrome 40 European ancestry cases, 40 European ancestry controls NA Affymetrix [93508] 0 chronic fatigue syndrome http://www.ebi.ac.uk/efo/EFO_0004540 GCST001223 Genome-wide genotyping array 80 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Endometrial cancer 2,188 European ancestry cases, 237,839 European ancestry controls, 1,200 East Asian ancestry cases, 60,614 East Asian ancestry controls NA Affymetrix, Illumina [25777865] (imputed) 2 endometrial carcinoma http://www.ebi.ac.uk/efo/EFO_1001512 GCST90018838 Genome-wide genotyping array 301841 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Endometriosis 4,511 European ancestry cases, 227,260 European ancestry controls, 1,786 East Asian ancestry cases, 80,975 East Asian ancestry controls NA Affymetrix, Illumina [25734875] (imputed) 7 endometriosis http://www.ebi.ac.uk/efo/EFO_0001065 GCST90018839 Genome-wide genotyping array 314532 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Epilepsy 4,382 European ancestry cases, 453,928 European ancestry controls, 2,466 East Asian ancestry cases, 175,788 East Asian ancestry controls NA Affymetrix, Illumina [25841675] (imputed) 2 epilepsy http://www.ebi.ac.uk/efo/EFO_0000474 GCST90018840 Genome-wide genotyping array 636564 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Esophageal cancer 998 European ancestry cases, 475,308 European ancestry controls, 1,388 East Asian ancestry cases, 159,201 East Asian ancestry controls NA Affymetrix, Illumina [25843129] (imputed) 4 esophageal carcinoma http://www.ebi.ac.uk/efo/EFO_0002916 GCST90018841 Genome-wide genotyping array 636895 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Esophageal varix 2,135 European ancestry cases, 434,019 European ancestry controls, 264 East Asian ancestry cases, 177,516 East Asian ancestry controls NA Affymetrix, Illumina [25840700] (imputed) 2 esophageal varices http://www.ebi.ac.uk/efo/EFO_0009545 GCST90018842 Genome-wide genotyping array 613934 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Bell's palsy 1,894 European ancestry cases, 461,346 European ancestry controls, 343 East Asian ancestry cases, 178,191 East Asian ancestry controls NA Affymetrix, Illumina [25842617] (imputed) 1 Bell's palsy http://www.ebi.ac.uk/efo/EFO_0007167 GCST90018843 Genome-wide genotyping array 641774 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Febrile seizures 2,366 European ancestry cases, 342,965 European ancestry controls, 574 East Asian ancestry cases, 175,272 East Asian ancestry controls NA Affymetrix, Illumina [20457414] (imputed) 0 Seizure http://purl.obolibrary.org/obo/HP_0001250 GCST90018844 Genome-wide genotyping array 521177 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Food allergy 182 European ancestry cases, 350,904 European ancestry controls, 3,777 East Asian ancestry cases, 165,939 East Asian ancestry controls NA Affymetrix, Illumina [20457211] (imputed) 0 food allergy measurement http://www.ebi.ac.uk/efo/EFO_0007016 GCST90018845 Genome-wide genotyping array 520802 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Gallbladder polyp 458 European ancestry cases, 340,083 European ancestry controls, 843 East Asian ancestry cases, 167,459 East Asian ancestry controls NA Affymetrix, Illumina [20456458] (imputed) 3 polyp of gallbladder http://purl.obolibrary.org/obo/MONDO_0021416 GCST90018846 Genome-wide genotyping array 508843 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Graves' disease 1,678 European ancestry cases, 456,942 European ancestry controls, 2,809 East Asian ancestry cases, 172,656 East Asian ancestry controls NA Affymetrix, Illumina [25841587] (imputed) 25 Graves disease http://www.ebi.ac.uk/efo/EFO_0004237 GCST90018847 Genome-wide genotyping array 634085 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Gastroesophageal reflux disease 32,957 European ancestry cases, 434,296 European ancestry controls, 948 East Asian ancestry cases, 177,516 East Asian ancestry controls NA Affymetrix, Illumina [25843127] (imputed) 2 gastroesophageal reflux disease http://www.ebi.ac.uk/efo/EFO_0003948 GCST90018848 Genome-wide genotyping array 645717 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Gastric cancer 1,029 European ancestry cases, 475,087 European ancestry controls, 7,921 East Asian ancestry cases, 159,201 East Asian ancestry controls NA Affymetrix, Illumina [25843697] (imputed) 7 gastric carcinoma http://www.ebi.ac.uk/efo/EFO_0000178 GCST90018849 Genome-wide genotyping array 643238 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Gastric polyp 6,155 European ancestry cases, 341,871 European ancestry controls, 1,337 East Asian ancestry cases, 158,249 East Asian ancestry controls NA Affymetrix, Illumina [20456140] (imputed) 5 stomach polyp http://purl.obolibrary.org/obo/MONDO_0008277 GCST90018850 Genome-wide genotyping array 507612 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Gastric ulcer 6,293 European ancestry cases, 467,985 European ancestry controls, 12,650 East Asian ancestry cases, 161,227 East Asian ancestry controls NA Affymetrix, Illumina [25842546] (imputed) 5 gastric ulcer http://www.ebi.ac.uk/efo/EFO_0009454 GCST90018851 Genome-wide genotyping array 648155 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Glaucoma 10,411 European ancestry cases, 474,568 European ancestry controls, 8,448 East Asian ancestry cases, 168,903 East Asian ancestry controls NA Affymetrix, Illumina [25844939] (imputed) 37 glaucoma http://www.ebi.ac.uk/efo/EFO_0000516 GCST90018852 Genome-wide genotyping array 662330 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Goiter 2,711 European ancestry cases, 456,942 European ancestry controls, 1,127 East Asian ancestry cases, 172,656 East Asian ancestry controls NA Affymetrix, Illumina [25841617] (imputed) 16 goiter http://www.ebi.ac.uk/efo/EFO_0004283 GCST90018853 Genome-wide genotyping array 633436 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Acute hepatitis A infection 69 European ancestry cases, 351,740 European ancestry controls, 261 East Asian ancestry cases, 166,603 East Asian ancestry controls NA Affymetrix, Illumina [20456890] (imputed) 0 hepatitis A virus infection http://www.ebi.ac.uk/efo/EFO_0007305 GCST90018854 Genome-wide genotyping array 518673 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Hashimoto thyroiditis 15,654 European ancestry cases, 379,986 European ancestry controls, 537 East Asian ancestry cases, 172,656 East Asian ancestry controls NA Affymetrix, Illumina [25797652] (imputed) 14 Hashimoto's thyroiditis http://www.ebi.ac.uk/efo/EFO_0003779 GCST90018855 Genome-wide genotyping array 568833 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Head injury 7,746 European ancestry cases, 349,912 European ancestry controls, 2,440 East Asian ancestry cases, 176,286 East Asian ancestry controls NA Affymetrix, Illumina [20458276] (imputed) 0 head injury http://www.ebi.ac.uk/efo/EFO_0009505 GCST90018856 Genome-wide genotyping array 536384 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Hearing loss, difficulty in hearing 14,654 European ancestry cases, 474,839 European ancestry controls, 3,400 East Asian ancestry cases, 175,326 East Asian ancestry controls NA Affymetrix, Illumina [25845022] (imputed) 4 hearing loss http://www.ebi.ac.uk/efo/EFO_0004238 GCST90018857 Genome-wide genotyping array 668219 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Hepatic cancer 379 European ancestry cases, 475,259 European ancestry controls, 2,122 East Asian ancestry cases, 159,201 East Asian ancestry controls NA Affymetrix, Illumina [25843189] (imputed) 4 liver neoplasm http://www.ebi.ac.uk/efo/EFO_1001513 GCST90018858 Genome-wide genotyping array 636961 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Herpes infection 313 European ancestry cases, 351,740 European ancestry controls, 772 East Asian ancestry cases, 166,603 East Asian ancestry controls NA Affymetrix, Illumina [20456945] (imputed) 0 Herpes simplex infection http://www.ebi.ac.uk/efo/EFO_1002022 GCST90018859 Genome-wide genotyping array 519428 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Hyperthyroidism 3,557 European ancestry cases, 456,942 European ancestry controls, 994 East Asian ancestry cases, 172,656 East Asian ancestry controls NA Affymetrix, Illumina [25841580] (imputed) 11 Hyperthyroidism http://www.ebi.ac.uk/efo/EFO_0009189 GCST90018860 Genome-wide genotyping array 634149 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Hypertrophic cardiomyopathy 507 European ancestry cases, 489,220 European ancestry controls, 383 East Asian ancestry cases, 177,745 East Asian ancestry controls NA Affymetrix, Illumina [25845237] (imputed) 6 hypertrophic cardiomyopathy http://www.ebi.ac.uk/efo/EFO_0000538 GCST90018861 Genome-wide genotyping array 667855 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Hypothyroidism 30,155 European ancestry cases, 379,986 European ancestry controls, 1,114 East Asian ancestry cases, 172,656 East Asian ancestry controls NA Affymetrix, Illumina [25801083] (imputed) 77 hypothyroidism http://www.ebi.ac.uk/efo/EFO_0004705 GCST90018862 Genome-wide genotyping array 583911 2013-06-06 23468962 Song C 2013-02-28 PLoS One www.ncbi.nlm.nih.gov/pubmed/23468962 A genome-wide scan for breast cancer risk haplotypes among African American women. Breast cancer 3,016 African American cases, 2,745 African American controls NA Illumina [1006480] 13 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST001879 Genome-wide genotyping array 5761 2013-06-16 23474815 Stambolian D 2013-03-07 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23474815 Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error. Refractive error 6,597 European ancestry and Erasmus Rucphen individuals, 683 Sardinian inidividuals 19,763 European ancestry individuals Affymetrix, Illumina [2093862] (imputed) 1 Abnormality of refraction http://purl.obolibrary.org/obo/HP_0000539 GCST001898 Genome-wide genotyping array 7280 2010-08-17 20664687 Lin HJ 2010-07-01 Mol Vis www.ncbi.nlm.nih.gov/pubmed/20664687 Single-nucleotide polymorphisms in chromosome 3p14.1- 3p14.2 are associated with susceptibility of type 2 diabetes with cataract. Cataracts in type 2 diabetes 109 Han Chinese ancestry cases, 649 Han Chinese ancestry controls NA Illumina [517401] 0 diabetes mellitus type 2 associated cataract http://www.ebi.ac.uk/efo/EFO_0004596 GCST000717 Genome-wide genotyping array 758 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Ovarian cancer 1,588 European ancestry cases, 244,932 European ancestry controls, 843 East Asian ancestry cases, 60,614 East Asian ancestry controls NA Affymetrix, Illumina [25778302] (imputed) 0 ovarian carcinoma http://www.ebi.ac.uk/efo/EFO_0001075 GCST90018888 Genome-wide genotyping array 307977 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Ovarian cyst 10,847 European ancestry cases, 207,622 European ancestry controls, 2,896 East Asian ancestry cases, 79,865 East Asian ancestry controls NA Affymetrix, Illumina [25752875] (imputed) 5 Ovarian cyst http://purl.obolibrary.org/obo/HP_0000138 GCST90018889 Genome-wide genotyping array 301230 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Peripheral artery disease 7,114 European ancestry cases, 475,964 European ancestry controls, 4,112 East Asian ancestry cases, 173,601 East Asian ancestry controls NA Affymetrix, Illumina [25844651] (imputed) 7 peripheral arterial disease http://www.ebi.ac.uk/efo/EFO_0004265 GCST90018890 Genome-wide genotyping array 660791 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Polymyositis 44 European ancestry cases, 350,228 European ancestry controls, 58 East Asian ancestry cases, 175,599 East Asian ancestry controls NA Affymetrix, Illumina [20457706] (imputed) 1 polymyositis http://www.ebi.ac.uk/efo/EFO_0003063 GCST90018891 Genome-wide genotyping array 525929 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pulmonary tuberculosis 895 European ancestry cases, 476,491 European ancestry controls, 7,800 East Asian ancestry cases, 170,871 East Asian ancestry controls NA Affymetrix, Illumina [25844658] (imputed) 1 pulmonary tuberculosis http://www.ebi.ac.uk/efo/EFO_1000049 GCST90018892 Genome-wide genotyping array 656057 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pancreatic cancer 1,196 European ancestry cases, 475,049 European ancestry controls, 499 East Asian ancestry cases, 159,201 East Asian ancestry controls NA Affymetrix, Illumina [25843042] (imputed) 0 pancreatic carcinoma http://www.ebi.ac.uk/efo/EFO_0002618 GCST90018893 Genome-wide genotyping array 635945 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Parkinson's disease 2,638 European ancestry cases, 477,380 European ancestry controls, 340 East Asian ancestry cases, 175,788 East Asian ancestry controls NA Affymetrix, Illumina [25844586] (imputed) 2 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST90018894 Genome-wide genotyping array 656146 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pediatric asthma 27,712 European ancestry cases, 411,131 European ancestry controls, 547 East Asian ancestry cases, 161,803 East Asian ancestry controls NA Affymetrix, Illumina [25832605] (imputed) 35 childhood onset asthma http://www.ebi.ac.uk/efo/EFO_0004591 GCST90018895 Genome-wide genotyping array 601193 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pericarditis 1,795 European ancestry cases, 453,370 European ancestry controls, 89 East Asian ancestry cases, 177,745 East Asian ancestry controls NA Affymetrix, Illumina [25837988] (imputed) 0 pericarditis http://www.ebi.ac.uk/efo/EFO_0007427 GCST90018896 Genome-wide genotyping array 632999 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Periodontal disease 1,740 European ancestry cases, 347,186 European ancestry controls, 9,560 East Asian ancestry cases, 169,166 East Asian ancestry controls NA Affymetrix, Illumina [20457829] (imputed) 0 periodontitis http://www.ebi.ac.uk/efo/EFO_0000649 GCST90018897 Genome-wide genotyping array 527652 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pharyngeal and laryngeal cancer 329 European ancestry cases, 355,235 European ancestry controls, 300 East Asian ancestry cases, 178,426 East Asian ancestry controls NA Affymetrix, Illumina [20458189] (imputed) 0 pharynx cancer, laryngeal carcinoma http://www.ebi.ac.uk/efo/EFO_0005577, http://purl.obolibrary.org/obo/MONDO_0002358 GCST90018898 Genome-wide genotyping array 534290 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pleurisy 8,528 European ancestry cases, 475,987 European ancestry controls, 541 East Asian ancestry cases, 176,974 East Asian ancestry controls NA Affymetrix, Illumina [25844732] (imputed) 0 pleurisy http://www.ebi.ac.uk/efo/EFO_1001825 GCST90018899 Genome-wide genotyping array 662030 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pneumoconiosis 433 European ancestry cases, 478,607 European ancestry controls, 85 East Asian ancestry cases, 176,974 East Asian ancestry controls NA Affymetrix, Illumina [25844546] (imputed) 0 pneumoconiosis http://www.orpha.net/ORDO/Orphanet_182098 GCST90018900 Genome-wide genotyping array 656099 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pneumonia 16,887 European ancestry cases, 463,412 European ancestry controls, 7,423 East Asian ancestry cases, 171,303 East Asian ancestry controls NA Affymetrix, Illumina [25843326] (imputed) 1 pneumonia http://www.ebi.ac.uk/efo/EFO_0003106 GCST90018901 Genome-wide genotyping array 659025 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pneumothorax 1,747 European ancestry cases, 475,987 European ancestry controls, 692 East Asian ancestry cases, 176,298 East Asian ancestry controls NA Affymetrix, Illumina [25844290] (imputed) 2 pneumothorax http://purl.obolibrary.org/obo/MONDO_0002076 GCST90018902 Genome-wide genotyping array 654724 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pollinosis 2,894 European ancestry cases, 472,484 European ancestry controls, 18,593 East Asian ancestry cases, 153,666 East Asian ancestry controls NA Affymetrix, Illumina [25844049] (imputed) 5 seasonal allergic rhinitis http://www.ebi.ac.uk/efo/EFO_0003956 GCST90018903 Genome-wide genotyping array 647637 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Polycystic kidney disease 424 European ancestry cases, 355,431 European ancestry controls, 510 East Asian ancestry cases, 178,216 East Asian ancestry controls NA Affymetrix, Illumina [20458172] (imputed) 0 Polycystic Kidney Disease http://www.ebi.ac.uk/efo/EFO_0008620 GCST90018904 Genome-wide genotyping array 534581 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Prostate cancer 11,599 European ancestry cases, 199,628 European ancestry controls, 5,672 East Asian ancestry cases, 84,660 East Asian ancestry controls NA Affymetrix, Illumina [25775424] (imputed) 59 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST90018905 Genome-wide genotyping array 301559 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Preeclampsia 2,355 European ancestry cases, 264,887 European ancestry controls, 123 East Asian ancestry cases, 81,962 East Asian ancestry controls NA Affymetrix, Illumina [25813232] (imputed) 0 preeclampsia http://www.ebi.ac.uk/efo/EFO_0000668 GCST90018906 Genome-wide genotyping array 349327 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Psoriasis vulgaris 5,072 European ancestry cases, 478,102 European ancestry controls, 206 East Asian ancestry cases, 172,289 East Asian ancestry controls NA Affymetrix, Illumina [25844455] (imputed) 10 psoriasis vulgaris http://www.ebi.ac.uk/efo/EFO_1001494 GCST90018907 Genome-wide genotyping array 655669 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pulmonary fibrosis 1,566 European ancestry cases, 467,560 European ancestry controls, 126 East Asian ancestry cases, 176,974 East Asian ancestry controls NA Affymetrix, Illumina [25843031] (imputed) 6 pulmonary fibrosis http://www.ebi.ac.uk/efo/EFO_0009448 GCST90018908 Genome-wide genotyping array 646226 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pyelonephritis 7,992 European ancestry cases, 454,495 European ancestry controls, 1,811 East Asian ancestry cases, 175,288 East Asian ancestry controls NA Affymetrix, Illumina [25843519] (imputed) 0 pyelonephritis http://www.ebi.ac.uk/efo/EFO_1001141 GCST90018909 Genome-wide genotyping array 639586 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Rheumatoid arthritis 8,255 European ancestry cases, 409,001 European ancestry controls, 5,348 East Asian ancestry cases, 173,268 East Asian ancestry controls NA Affymetrix, Illumina [25835038] (imputed) 21 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST90018910 Genome-wide genotyping array 595872 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Retinal detachment 6,591 European ancestry cases, 470,440 European ancestry controls, 1,389 East Asian ancestry cases, 168,903 East Asian ancestry controls NA Affymetrix, Illumina [25843609] (imputed) 4 retinal detachment http://www.ebi.ac.uk/efo/EFO_0005773 GCST90018911 Genome-wide genotyping array 647323 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Retinitis pigmentosa 121 European ancestry cases, 126,333 European ancestry controls, 155 East Asian ancestry cases, 168,903 East Asian ancestry controls NA Illumina [23539365] (imputed) 5 Retinitis pigmentosa http://www.orpha.net/ORDO/Orphanet_791 GCST90018912 Genome-wide genotyping array 295512 2009-01-07 19030899 Lei SF 2008-11-23 Hum Genet www.ncbi.nlm.nih.gov/pubmed/19030899 Genome-wide association scan for stature in Chinese: evidence for ethnic specific loci. Height 618 Chinese ancestry individuals 2,953 Chinese ancestry individuals Affymetrix [281533] 1 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST000272 Genome-wide genotyping array 618 2012-01-14 22156575 Paus T 2011-12-09 Cereb Cortex www.ncbi.nlm.nih.gov/pubmed/22156575 KCTD8 gene and brain growth in adverse intrauterine environment: a genome-wide association study. Brain development 557 French Canadian female adolescent individuals 2,601 European ancestry adolescent individuals Illumina [530011] 0 infant head circumference http://www.ebi.ac.uk/efo/EFO_0004577 GCST001349 Genome-wide genotyping array 557 2013-06-20 23496005 Luca G 2013-03-18 J Sleep Res www.ncbi.nlm.nih.gov/pubmed/23496005 Clinical, polysomnographic and genome-wide association analyses of narcolepsy with cataplexy: a European Narcolepsy Network study. Narcolepsy with cataplexy 585 European ancestry cases 387 European ancestry cases NR [NR] 4 narcolepsy with cataplexy http://www.ebi.ac.uk/efo/EFO_0000614 GCST001909 Genome-wide genotyping array 585 2013-06-18 23536807 Scheetz TE 2013-03-11 PLoS One www.ncbi.nlm.nih.gov/pubmed/23536807 A genome-wide association study for primary open angle glaucoma and macular degeneration reveals novel Loci. Age-related macular degeneration 200 cases, 197 controls 200 cases, 200 controls Affymetrix [500000] 2 glaucoma, age-related macular degeneration http://www.ebi.ac.uk/efo/EFO_0000516, http://www.ebi.ac.uk/efo/EFO_0001365 GCST001899 Genome-wide genotyping array 397 2013-03-19 23209189 Tabassum R 2012-12-03 Diabetes www.ncbi.nlm.nih.gov/pubmed/23209189 Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21. Type 2 diabetes 1,101 Indo-European ancestry cases, 1,027 Indo-European ancestry controls 3,607 Indo-European ancestry cases, 2,924 Indo-European ancestry controls, 1,184 Dravidian ancestry cases, 1,061 Dravidian ancestry controls, 11,285 European ancestry cases, 11,285 European ancestry controls Illumina [536420] 6 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST001759 Genome-wide genotyping array 2128 2013-06-18 23561647 van Setten J 2013-03-13 Atherosclerosis www.ncbi.nlm.nih.gov/pubmed/23561647 Genome-wide association study of coronary and aortic calcification implicates risk loci for coronary artery disease and myocardial infarction. Coronary artery calcification 2,620 European ancestry males NA Illumina [2500000] (imputed) 2 coronary artery calcification http://www.ebi.ac.uk/efo/EFO_0004723 GCST001902 Genome-wide genotyping array 2620 2013-04-09 22982463 Tang WH 2012-09-13 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/22982463 Clinical and genetic association of serum paraoxonase and arylesterase activities with cardiovascular risk. Paraoxonase activity 2,136 European ancestry individuals NA Affymetrix [2421770] (imputed) 2 arylesterase enzyme measurement http://www.ebi.ac.uk/efo/EFO_0005126 GCST001677 Genome-wide genotyping array 2136 2012-08-14 22832961 Kamboh MI 2012-05-15 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/22832961 Genome-wide association study of Alzheimer's disease. Alzheimer's disease 1,291 European ancestry cases, 938 European ancestry controls 509 European ancestry cases, 753 European ancestry controls, 2,218 cases, 2,583 controls Illumina [2543888] (imputed) 8 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST001529 Genome-wide genotyping array 2229 2012-01-27 22086417 Cozen W 2011-11-15 Blood www.ncbi.nlm.nih.gov/pubmed/22086417 A genome-wide meta-analysis of nodular sclerosing Hodgkin lymphoma identifies risk loci at 6p21.32. Nodular sclerosis Hodgkin lymphoma 393 European ancestry cases, 3,315 European ancestry controls 113 European ancestry cases, 214 European ancestry controls Illumina [705591] 2 nodular sclerosis Hodgkin lymphoma http://www.ebi.ac.uk/efo/EFO_0004708 GCST001323 Genome-wide genotyping array 3708 2013-05-09 23376709 Kerns SL 2013-01-31 J Urol www.ncbi.nlm.nih.gov/pubmed/23376709 A 2-stage genome-wide association study to identify single nucleotide polymorphisms associated with development of urinary symptoms after radiotherapy for prostate cancer. Urinary symptoms in response to radiotherapy in prostate cancer 346 European, African, Hispanic and Asian ancestry individuals 377 European, African, Hispanic and Asian ancestry individuals Affymetrix [613496] 1 response to radiation, lower urinary tract symptom http://purl.obolibrary.org/obo/GO_0009314, http://www.ebi.ac.uk/efo/EFO_0008008 GCST001847 Genome-wide genotyping array 346 2011-12-14 22087292 Sun L 2011-11-07 PLoS One www.ncbi.nlm.nih.gov/pubmed/22087292 Bivariate genome-wide association analyses of femoral neck bone geometry and appendicular lean mass. Femoral neck bone geometry 1,627 Han Chinese ancestry individuals 2,286 European ancestry individuals Affymetrix [689368] 2 femoral neck bone geometry http://www.ebi.ac.uk/efo/EFO_0004511 GCST001315 Genome-wide genotyping array 1627 2012-12-02 23001122 Orr N 2012-09-23 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23001122 Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk. Breast cancer (male) 823 European ancestry cases, 2,795 European ancestry controls 438 European ancestry cases, 474 European ancestry controls Illumina [447760] 3 male breast carcinoma http://www.ebi.ac.uk/efo/EFO_0006861 GCST001690 Genome-wide genotyping array 3618 2013-01-09 23100282 Hopewell JC 2012-10-24 Eur Heart J www.ncbi.nlm.nih.gov/pubmed/23100282 Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study. Response to statin therapy 3,895 European ancestry individuals 14,810 individuals Illumina [546210] 0 response to statin http://purl.obolibrary.org/obo/GO_0036273 GCST001716 Genome-wide genotyping array 3895 2013-03-11 23242368 Jiang DK 2012-12-16 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23242368 Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. Hepatocellular carcinoma in hepatitis B infection 1,161 Chinese ancestry cases, 1,353 Chinese ancestry controls 4,319 Chinese ancestry cases, 4,966 Chinese ancestry controls Illumina [1672517] (imputed) 2 hepatocellular carcinoma http://www.ebi.ac.uk/efo/EFO_0000182 GCST001775 Genome-wide genotyping array 2514 2012-08-15 22672568 Heit JA 2012-06-05 J Thromb Haemost www.ncbi.nlm.nih.gov/pubmed/22672568 A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q. Venous thromboembolism 1,503 European and other ancestry cases, 1,459 European and other ancestry controls 1,407 cases, 1,418 controls Illumina [~ 2500000] (imputed) 5 venous thromboembolism http://www.ebi.ac.uk/efo/EFO_0004286 GCST001557 Genome-wide genotyping array 2962 2012-05-24 22479191 Pattaro C 2012-03-29 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22479191 Genome-wide association and functional follow-up reveals new loci for kidney function. Chronic kidney disease 74,354 European ancestry individuals 56,246 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 2 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST001466 Genome-wide genotyping array 74354 2012-04-06 22419738 Osman W 2012-03-22 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22419738 A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma. Glaucoma (primary open-angle) 1,394 Japanese ancestry cases, 6,599 Japanese ancestry controls 1,802 Japanese ancestry cases, 7,212 Japanese ancestry controls Illumina [602216] 3 open-angle glaucoma http://www.ebi.ac.uk/efo/EFO_0004190 GCST001451 Genome-wide genotyping array 7993 2009-03-24 19268276 Vink JM 2009-03-04 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/19268276 Genome-wide association study of smoking initiation and current smoking. Smoking behavior 3,497 European ancestry individuals 6,215 individuals, 1,648 twins Perlegen [427037] 0 smoking behavior http://www.ebi.ac.uk/efo/EFO_0004318 GCST000351 Genome-wide genotyping array 3497 2013-03-22 23269536 Sun J 2012-12-27 Hum Genet www.ncbi.nlm.nih.gov/pubmed/23269536 Genome-wide association study identified novel genetic variant on SLC45A3 gene associated with serum levels prostate-specific antigen (PSA) in a Chinese population. Prostate-specific antigen levels 1,999 Chinese ancestry males 1,496 Chinese ancestry males Illumina [> 709211] (imputed) 3 prostate specific antigen measurement http://www.ebi.ac.uk/efo/EFO_0004624 GCST001796 Genome-wide genotyping array 1999 2013-05-01 23382809 Xu C 2013-01-29 PLoS One www.ncbi.nlm.nih.gov/pubmed/23382809 BCL9 and C9orf5 are associated with negative symptoms in schizophrenia: meta-analysis of two genome-wide association studies. Schizophrenia (negative symptoms) 1,774 European ancestry cases, 2,726 European ancestry controls NA Affymetrix [729454] 3 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST001836 Genome-wide genotyping array 4500 2013-05-21 23437003 Paternoster L 2013-02-21 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/23437003 Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure. Bone mineral density up to 5,878 European ancestry individuals up to 1,052 European ancestry individuals Illumina [2401124] (imputed) 7 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST001870 Genome-wide genotyping array 5878 2013-02-08 23223146 Le Clerc S 2012-12-06 J Invest Dermatol www.ncbi.nlm.nih.gov/pubmed/23223146 A genome-wide association study in Caucasian women points out a putative role of the STXBP5L gene in facial photoaging. Aging (facial) 502 European ancestry females NA Illumina [795063] 4 aging http://purl.obolibrary.org/obo/GO_0007568 GCST001767 Genome-wide genotyping array 502 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Interstitial lung disease 2,267 European ancestry cases, 467,560 European ancestry controls, 1,046 East Asian ancestry cases, 176,974 East Asian ancestry controls NA Affymetrix, Illumina [25843170] (imputed) 8 interstitial lung disease http://www.ebi.ac.uk/efo/EFO_0004244 GCST90018863 Genome-wide genotyping array 647847 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Ischemic stroke 11,929 European ancestry cases, 472,192 European ancestry controls, 22,664 East Asian ancestry cases, 152,022 East Asian ancestry controls NA Affymetrix, Illumina [25844498] (imputed) 15 Ischemic stroke http://purl.obolibrary.org/obo/HP_0002140 GCST90018864 Genome-wide genotyping array 658807 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Idiopathic thrombocytopenic purpura 675 European ancestry cases, 488,749 European ancestry controls, 168 East Asian ancestry cases, 178,558 East Asian ancestry controls NA Affymetrix, Illumina [25845163] (imputed) 0 autoimmune thrombocytopenic purpura http://www.ebi.ac.uk/efo/EFO_0007160 GCST90018865 Genome-wide genotyping array 668150 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. IgA nephropathy 15,587 European ancestry cases, 462,197 European ancestry controls, 71 East Asian ancestry cases, 175,288 East Asian ancestry controls NA Affymetrix, Illumina [25844273] (imputed) 8 IGA glomerulonephritis http://www.ebi.ac.uk/efo/EFO_0004194 GCST90018866 Genome-wide genotyping array 653143 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Ileus 2,911 European ancestry cases, 395,721 European ancestry controls, 1,771 East Asian ancestry cases, 176,232 East Asian ancestry controls NA Affymetrix, Illumina [25838128] (imputed) 0 ileus http://purl.obolibrary.org/obo/MONDO_0004567 GCST90018867 Genome-wide genotyping array 576635 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Inguinal hernia 16,725 European ancestry cases, 428,356 European ancestry controls, 1,664 East Asian ancestry cases, 177,062 East Asian ancestry controls NA Affymetrix, Illumina [25841416] (imputed) 23 Inguinal hernia http://purl.obolibrary.org/obo/HP_0000023 GCST90018868 Genome-wide genotyping array 623807 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Insomnia 1,402 European ancestry cases, 485,225 European ancestry controls, 389 East Asian ancestry cases, 177,864 East Asian ancestry controls NA Affymetrix, Illumina [25845016] (imputed) 1 insomnia measurement http://www.ebi.ac.uk/efo/EFO_0007876 GCST90018869 Genome-wide genotyping array 664880 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Intracerebral hemorrhage 1,935 European ancestry cases, 471,578 European ancestry controls, 1,456 East Asian ancestry cases, 152,022 East Asian ancestry controls NA Affymetrix, Illumina [25841532] (imputed) 3 intracerebral hemorrhage http://www.ebi.ac.uk/efo/EFO_0005669 GCST90018870 Genome-wide genotyping array 626991 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Iritis 2,616 European ancestry cases, 478,126 European ancestry controls, 110 East Asian ancestry cases, 175,543 East Asian ancestry controls NA Affymetrix, Illumina [25844196] (imputed) 6 iritis http://www.ebi.ac.uk/efo/EFO_1000997 GCST90018871 Genome-wide genotyping array 656395 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Iron deficiency anemia 12,317 European ancestry cases, 468,624 European ancestry controls, 4,618 East Asian ancestry cases, 174,057 East Asian ancestry controls NA Affymetrix, Illumina [25844780] (imputed) 4 anemia (phenotype) http://www.ebi.ac.uk/efo/EFO_0004272 GCST90018872 Genome-wide genotyping array 659616 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Juvenile rheumatoid arthritis 216 European ancestry cases, 409,001 European ancestry controls, 110 East Asian ancestry cases, 173,268 East Asian ancestry controls NA Affymetrix, Illumina [25833140] (imputed) 1 juvenile idiopathic arthritis http://www.ebi.ac.uk/efo/EFO_0002609 GCST90018873 Genome-wide genotyping array 582595 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Keloid 668 European ancestry cases, 481,244 European ancestry controls, 1,055 East Asian ancestry cases, 177,671 East Asian ancestry controls NA Affymetrix, Illumina [25844469] (imputed) 5 Keloid http://www.ebi.ac.uk/efo/EFO_0004212 GCST90018874 Genome-wide genotyping array 660638 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Lung cancer 3,791 European ancestry cases, 489,012 European ancestry controls, 4,444 East Asian ancestry cases, 174,282 East Asian ancestry controls NA Affymetrix, Illumina [25845450] (imputed) 11 lung carcinoma http://www.ebi.ac.uk/efo/EFO_0001071 GCST90018875 Genome-wide genotyping array 671529 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Myasthenia gravis 197 European ancestry cases, 354,945 European ancestry controls, 81 East Asian ancestry cases, 178,630 East Asian ancestry controls NA Affymetrix, Illumina [20458161] (imputed) 0 Myasthenia gravis http://www.ebi.ac.uk/efo/EFO_0004991 GCST90018876 Genome-wide genotyping array 533853 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Myocardial infarction 20,917 European ancestry cases, 440,906 European ancestry controls, 14,992 East Asian ancestry cases, 146,214 East Asian ancestry controls NA Affymetrix, Illumina [25841367] (imputed) 71 myocardial infarction http://www.ebi.ac.uk/efo/EFO_0000612 GCST90018877 Genome-wide genotyping array 623029 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Malignant lymphoma 3,546 European ancestry cases, 487,257 European ancestry controls, 335 East Asian ancestry cases, 177,342 East Asian ancestry controls NA Affymetrix, Illumina [25845276] (imputed) 7 lymphoma http://www.ebi.ac.uk/efo/EFO_0000574 GCST90018878 Genome-wide genotyping array 668480 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Mastopathy 2,541 European ancestry cases, 257,308 European ancestry controls, 575 East Asian ancestry cases, 82,186 East Asian ancestry controls NA Affymetrix, Illumina [25793968] (imputed) 1 breast fibrocystic disease http://www.ebi.ac.uk/efo/EFO_0003014 GCST90018879 Genome-wide genotyping array 342610 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Meniere's disease 1,526 European ancestry cases, 481,248 European ancestry controls, 1,290 East Asian ancestry cases, 177,436 East Asian ancestry controls NA Affymetrix, Illumina [25844443] (imputed) 3 Meniere disease http://www.ebi.ac.uk/efo/EFO_0006862 GCST90018880 Genome-wide genotyping array 661500 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Metal allergy 2,409 European ancestry cases, 350,904 European ancestry controls, 278 East Asian ancestry cases, 161,777 East Asian ancestry controls NA Affymetrix, Illumina [20456616] (imputed) 1 allergy http://www.ebi.ac.uk/efo/EFO_0003785 GCST90018881 Genome-wide genotyping array 515368 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Myocarditis 633 European ancestry cases, 427,278 European ancestry controls, 102 East Asian ancestry cases, 177,745 East Asian ancestry controls NA Affymetrix, Illumina [25823913] (imputed) 0 myocarditis http://www.ebi.ac.uk/efo/EFO_0009609 GCST90018882 Genome-wide genotyping array 605758 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Nasal polyps 5,093 European ancestry cases, 444,966 European ancestry controls, 160 East Asian ancestry cases, 151,846 East Asian ancestry controls NA Affymetrix, Illumina [25837843] (imputed) 22 Nasal Cavity Polyp http://www.ebi.ac.uk/efo/EFO_1000391 GCST90018883 Genome-wide genotyping array 602065 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Nephrotic syndrome 775 European ancestry cases, 475,255 European ancestry controls, 1,314 East Asian ancestry cases, 177,412 East Asian ancestry controls NA Affymetrix, Illumina [25844401] (imputed) 2 nephrotic syndrome http://www.ebi.ac.uk/efo/EFO_0004255 GCST90018884 Genome-wide genotyping array 654756 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Neuropathic bladder 2,237 European ancestry cases, 464,793 European ancestry controls, 308 East Asian ancestry cases, 178,418 East Asian ancestry controls NA Affymetrix, Illumina [25842983] (imputed) 2 bladder disease http://www.ebi.ac.uk/efo/EFO_1000018 GCST90018885 Genome-wide genotyping array 645756 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Non-tuberculous mycobacterial infection 26 European ancestry cases, 341,584 European ancestry controls, 64 East Asian ancestry cases, 172,320 East Asian ancestry controls NA Affymetrix, Illumina [20456798] (imputed) 0 Mycobacterium infection http://www.ebi.ac.uk/efo/EFO_0009429 GCST90018886 Genome-wide genotyping array 513994 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Osteoporosis 8,520 European ancestry cases, 479,981 European ancestry controls, 9,794 East Asian ancestry cases, 168,932 East Asian ancestry controls NA Affymetrix, Illumina [25844994] (imputed) 21 osteoporosis http://www.ebi.ac.uk/efo/EFO_0003882 GCST90018887 Genome-wide genotyping array 667227 2008-06-16 17158188 Bierut LJ 2006-12-07 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/17158188 Novel genes identified in a high-density genome wide association study for nicotine dependence. Nicotine dependence 482 European ancestry cases, 466 European ancestry controls 568 European ancestry cases, 413 European ancestry controls Perlegen [2400000] 2 nicotine dependence http://www.ebi.ac.uk/efo/EFO_0003768 GCST000010 Genome-wide genotyping array 948 2011-05-28 21552555 Wang K 2011-04-28 PLoS One www.ncbi.nlm.nih.gov/pubmed/21552555 A genome-wide association study on obesity and obesity-related traits. Obesity 520 European ancestry cases, 540 European ancestry controls 1,196 European ancestry individuals Illumina [~ 550000] 14 obesity http://www.ebi.ac.uk/efo/EFO_0001073 GCST001057 Genome-wide genotyping array 1060 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Hemoglobin A1c levels 71,221 East Asian ancestry individuals NA Illumina [13466143] (imputed) 25 hemoglobin A1 measurement http://www.ebi.ac.uk/efo/EFO_0007629 GCST90018738 Genome-wide genotyping array 71221 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Height 165,056 East Asian ancestry individuals NA Illumina [13479295] (imputed) 388 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST90018739 Genome-wide genotyping array 165056 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Hematocrit 153,015 East Asian ancestry individuals NA Illumina [13478961] (imputed) 51 hematocrit http://www.ebi.ac.uk/efo/EFO_0004348 GCST90018740 Genome-wide genotyping array 153015 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. LDL cholesterol 72,866 East Asian ancestry individuals NA Illumina [13461863] (imputed) 29 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST90018741 Genome-wide genotyping array 72866 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Lymphocyte counts 95,717 East Asian ancestry individuals NA Illumina [13471431] (imputed) 29 lymphocyte count http://www.ebi.ac.uk/efo/EFO_0004587 GCST90018742 Genome-wide genotyping array 95717 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Mean arterial pressure 145,502 East Asian ancestry individuals NA Illumina [13477767] (imputed) 35 mean arterial pressure http://www.ebi.ac.uk/efo/EFO_0006340 GCST90018743 Genome-wide genotyping array 145502 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Mean corpuscular hemoglobin 128,028 East Asian ancestry individuals NA Illumina [13476299] (imputed) 122 mean corpuscular hemoglobin http://www.ebi.ac.uk/efo/EFO_0004527 GCST90018744 Genome-wide genotyping array 128028 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Mean corpuscular hemoglobin concentration 135,482 East Asian ancestry individuals NA Illumina [13477028] (imputed) 48 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90018745 Genome-wide genotyping array 135482 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Mean corpuscular volume 129,832 East Asian ancestry individuals NA Illumina [13476266] (imputed) 134 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST90018746 Genome-wide genotyping array 129832 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Monocyte count 95,119 East Asian ancestry individuals NA Illumina [13471440] (imputed) 53 monocyte count http://www.ebi.ac.uk/efo/EFO_0005091 GCST90018747 Genome-wide genotyping array 95119 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Neutrophil count 82,810 East Asian ancestry individuals NA Illumina [13467171] (imputed) 29 neutrophil count http://www.ebi.ac.uk/efo/EFO_0004833 GCST90018748 Genome-wide genotyping array 82810 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Platelet count 148,623 East Asian ancestry individuals NA Illumina [13478928] (imputed) 136 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST90018749 Genome-wide genotyping array 148623 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pulse pressure 145,445 East Asian ancestry individuals NA Illumina [13477769] (imputed) 21 pulse pressure measurement http://www.ebi.ac.uk/efo/EFO_0005763 GCST90018750 Genome-wide genotyping array 145445 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Red blood cell count 153,512 East Asian ancestry individuals NA Illumina [13479135] (imputed) 97 erythrocyte count http://www.ebi.ac.uk/efo/EFO_0004305 GCST90018751 Genome-wide genotyping array 153512 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Systolic blood pressure 145,505 East Asian ancestry individuals NA Illumina [13477770] (imputed) 37 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST90018752 Genome-wide genotyping array 145505 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Total bilirubin levels 124,341 East Asian ancestry individuals NA Illumina [13476323] (imputed) 15 bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004570 GCST90018753 Genome-wide genotyping array 124341 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Total cholesterol levels 135,808 East Asian ancestry individuals NA Illumina [13476599] (imputed) 41 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST90018754 Genome-wide genotyping array 135808 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Triglycerides 111,667 East Asian ancestry individuals NA Illumina [13471903] (imputed) 28 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST90018755 Genome-wide genotyping array 111667 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Serum total protein level 133,321 East Asian ancestry individuals NA Illumina [13477433] (imputed) 38 total blood protein measurement http://www.ebi.ac.uk/efo/EFO_0004536 GCST90018756 Genome-wide genotyping array 133321 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Serum uric acid levels 129,405 East Asian ancestry individuals NA Illumina [13475706] (imputed) 40 uric acid measurement http://www.ebi.ac.uk/efo/EFO_0004761 GCST90018757 Genome-wide genotyping array 129405 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. White blood cell count 154,355 East Asian ancestry individuals NA Illumina [13479091] (imputed) 75 leukocyte count http://www.ebi.ac.uk/efo/EFO_0004308 GCST90018758 Genome-wide genotyping array 154355 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Serum creatinine levels 150,266 East Asian ancestry individuals NA Illumina [13478778] (imputed) 87 creatinine measurement http://www.ebi.ac.uk/efo/EFO_0004518 GCST90018759 Genome-wide genotyping array 150266 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (drugs for peptic ulcer and gastro-oesophageal reflux disease) 53,363 East Asian ancestry cases, 125,363 East Asian ancestry controls NA Illumina [13429980] (imputed) 1 Peptic ulcer and gastro-oesophageal reflux disease (GORD) drug use measurement http://www.ebi.ac.uk/efo/EFO_0009923 GCST90018760 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (drugs used in diabetes) 30,515 East Asian ancestry cases, 148,211 East Asian ancestry controls NA Illumina [13134967] (imputed) 65 Drugs used in diabetes use measurement http://www.ebi.ac.uk/efo/EFO_0009924 GCST90018761 Genome-wide genotyping array 178726 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (antithrombotic agents) 54,220 East Asian ancestry cases, 124,506 East Asian ancestry controls NA Illumina [13429980] (imputed) 20 Antithrombotic agent use measurement http://www.ebi.ac.uk/efo/EFO_0009925 GCST90018762 Genome-wide genotyping array 178726 2011-02-16 21155030 Cheong MY 2011-01-11 Yonsei Med J www.ncbi.nlm.nih.gov/pubmed/21155030 Association of the adiponectin gene variations with risk of ischemic stroke in a Korean population. Stroke (ischemic) 160 Korean ancestry cases, 160 Korean ancestry controls 673 Korean ancestry cases, 267 Korean ancestry controls Affymetrix [~ 320250] 0 stroke http://www.ebi.ac.uk/efo/EFO_0000712 GCST000941 Genome-wide genotyping array 320 2012-01-10 22171074 Tan A 2011-12-30 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22171074 A genome-wide association and gene-environment interaction study for serum triglycerides levels in a healthy Chinese male population. Triglycerides 1,999 Han Chinese ancestry male individuals 1,496 Han Chinese ancestry male individuals Illumina [1940243] (imputed) 3 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST001367 Genome-wide genotyping array 1999 2009-05-21 19421330 Yang HC 2009-05-07 PLoS One www.ncbi.nlm.nih.gov/pubmed/19421330 Genome-wide association study of young-onset hypertension in the Han Chinese population of Taiwan. Hypertension (young onset) 175 Han Chinese ancestry cases, 175 Han Chinese ancestry controls 833 Han Chinese ancestry cases, 833 Han Chinese ancestry controls Affymetrix [91713] 1 early onset hypertension http://www.ebi.ac.uk/efo/EFO_0004772 GCST000390 Genome-wide genotyping array 350 2009-05-21 19430760 Rich SS 2009-05-09 Diabetologia www.ncbi.nlm.nih.gov/pubmed/19430760 A genome-wide association scan for acute insulin response to glucose in Hispanic-Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS FS). Insulin resistance/response 229 Hispanic individuals from 34 families 961 Hispanic family members Illumina [309200] 0 insulin resistance http://www.ebi.ac.uk/efo/EFO_0002614 GCST000391 Genome-wide genotyping array 263 2010-09-23 20729852 Abnet CC 2010-08-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20729852 A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma. Esophageal cancer and gastric cancer 1,625 Chinese ancestry gastric cancer cases, 1,898 Chinese ancestry ESCC cases, 2,100 Chinese ancestry controls NA Illumina [551152] 4 esophageal carcinoma, gastric carcinoma http://www.ebi.ac.uk/efo/EFO_0002916, http://www.ebi.ac.uk/efo/EFO_0000178 GCST000777 Genome-wide genotyping array 5623 2010-09-14 20732627 Neale BM 2010-08-05 J Am Acad Child Adolesc Psychiatry www.ncbi.nlm.nih.gov/pubmed/20732627 Case-control genome-wide association study of attention-deficit/hyperactivity disorder. Attention deficit hyperactivity disorder 896 European ancestry cases, 2,455 European ancestry controls NA Affymetrix [1033244] (imputed) 0 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST000757 Genome-wide genotyping array 3351 2010-06-22 20522523 Kasperaviciute D 2010-06-03 Brain www.ncbi.nlm.nih.gov/pubmed/20522523 Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study. Partial epilepsies Up to 3,445 European ancestry cases, 6,935 European ancestry controls NA Illumina [528745] 6 partial epilepsy http://www.ebi.ac.uk/efo/EFO_0004263 GCST000691 Genome-wide genotyping array 10380 2012-09-21 22843503 Qi Q 2012-07-26 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22843503 Genome-wide association analysis identifies TYW3/CRYZ and NDST4 loci associated with circulating resistin levels. Resistin levels 3,248 European ancestry individuals 659 European ancestry individuals Affymetrix, Illumina [2543887] (imputed) 4 resistin measurement http://www.ebi.ac.uk/efo/EFO_0004819 GCST001620 Genome-wide genotyping array 3248 2012-11-22 22699663 Divaris K 2012-07-01 J Dent Res www.ncbi.nlm.nih.gov/pubmed/22699663 Genome-wide association study of periodontal pathogen colonization. Periodontal microbiota 1,020 European ancestry individuals NA Affymetrix [~ 2500000] (imputed) 16 periodontitis http://www.ebi.ac.uk/efo/EFO_0000649 GCST001588 Genome-wide genotyping array 1020 2011-06-03 21602798 Haiman CA 2011-05-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21602798 Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21. Prostate cancer 3,425 African American cases, 3,290 African American controls 1,500 African American/Afro-Caribbean cases, 1,908 African American/Afro-Caribbean controls, 344 Sub-Saharan African ancestry cases, 1,361 Sub-Saharan African ancestry controls Illumina [10471986] 1 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST001078 Genome-wide genotyping array 6715 2012-04-03 22428042 Nakano M 2012-03-12 PLoS One www.ncbi.nlm.nih.gov/pubmed/22428042 Common variants in CDKN2B-AS1 associated with optic-nerve vulnerability of glaucoma identified by genome-wide association studies in Japanese. Glaucoma (primary open-angle) 833 Japanese ancestry cases, 686 Japanese ancestry controls 411 Japanese ancestry cases, 289 Japanese ancestry controls Affymetrix [653519] 1 open-angle glaucoma http://www.ebi.ac.uk/efo/EFO_0004190 GCST001441 Genome-wide genotyping array 1519 2012-12-05 23001564 Mangino M 2012-09-25 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23001564 Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans. Telomere length 9,190 European ancestry individuals 2,226 individuals Affymetrix, Illumina [~ 2500000] (imputed) 4 telomere length http://www.ebi.ac.uk/efo/EFO_0004505 GCST001697 Genome-wide genotyping array 9190 2011-07-27 21738484 Smith EN 2011-06-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21738484 Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes. Bipolar disorder 1,190 European and unknown ancestry cases, 401 European and unknown ancestry controls 16,179 individuals Affymetrix [703019] 6 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST001135 Genome-wide genotyping array 1591 2011-07-21 21738478 Okada Y 2011-06-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21738478 Identification of nine novel loci associated with white blood cell subtypes in a Japanese population. White blood cell types 8,794 Japanese ancestry individuals 5,998 Japanese ancestry individuals Illumina [2178645] (imputed) 20 leukocyte count http://www.ebi.ac.uk/efo/EFO_0004308 GCST001134 Genome-wide genotyping array 8794 2011-07-20 21738487 Do CB 2011-06-23 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21738487 Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease. Parkinson's disease 3,426 European ancestry cases, 29,624 European ancestry controls NA Illumina [522782] 11 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST001126 Genome-wide genotyping array 33050 2012-06-27 22570697 Matesanz F 2012-05-03 PLoS One www.ncbi.nlm.nih.gov/pubmed/22570697 Genome-wide association study of multiple sclerosis confirms a novel locus at 5p13.1. Multiple sclerosis 2,127 European ancestry cases, 4,558 European ancestry controls 2,785 European ancestry cases, 2,940 European ancestry controls Affymetrix, Illumina [130903] 1 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST001505 Genome-wide genotyping array 6685 2012-06-27 22551897 Mahasirimongkol S 2012-05-03 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/22551897 Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis. Tuberculosis 433 Thai ancestry cases, 295 Thai ancestry controls, 188 Japanese ancestry cases, 934 Japanese ancestry controls 369 Thai ancestry cases, 439 Thai ancestry controls, 112 Japanese ancestry cases, 1,089 Japanese ancestry controls Illumina [533252] 0 Tuberculosis http://www.orpha.net/ORDO/Orphanet_3389 GCST001504 Genome-wide genotyping array 1850 2013-05-26 23455491 Zuo L 2013-02-27 Drug Alcohol Depend www.ncbi.nlm.nih.gov/pubmed/23455491 NKAIN1-SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent. Alcohol dependence 1,409 European ancestry cases, 1,518 European ancestry controls 6,438 European ancestry individuals from 1,645 affected families Illumina [805814] 1 alcohol dependence http://www.ebi.ac.uk/efo/EFO_0003829 GCST001874 Genome-wide genotyping array 2927 2012-06-18 22524403 Rice JP 2012-04-24 Addiction www.ncbi.nlm.nih.gov/pubmed/22524403 CHRNB3 is more strongly associated with Fagerström test for cigarette dependence-based nicotine dependence than cigarettes per day: phenotype definition changes genome-wide association studies results. Nicotine dependence 2,267 European ancestry individuals, 99 Hispanic individuals, 999 African American individuals 835 individuals Illumina [948658] 1 nicotine dependence http://www.ebi.ac.uk/efo/EFO_0003768 GCST001490 Genome-wide genotyping array 3365 2009-03-24 19268274 Liu XG 2009-03-04 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/19268274 Genome-wide association and replication studies identified TRHR as an important gene for lean body mass. Body mass (lean) 973 European ancestry individuals 1,488 European ancestry individuals, 1,972 European ancestry individuals from 593 families, 2,955 Chinese ancestry individuals Affymetrix [379319] 1 lean body mass http://www.ebi.ac.uk/efo/EFO_0004995 GCST000352 Genome-wide genotyping array 973 2011-10-16 21946350 Soler Artigas M 2011-09-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21946350 Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Pulmonary function 48,201 European ancestry individuals 46,411 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 18 pulmonary function measurement http://www.ebi.ac.uk/efo/EFO_0003892 GCST001248 Genome-wide genotyping array 48201 2011-10-18 21946350 Soler Artigas M 2011-09-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21946350 Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Pulmonary function 48,201 European ancestry individuals 46,411 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 16 pulmonary function measurement http://www.ebi.ac.uk/efo/EFO_0003892 GCST001251 Genome-wide genotyping array 48201 2012-08-14 22688191 Bergen SE 2012-06-12 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/22688191 Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder. Schizophrenia 2,111 European ancestry cases, 2,535 European ancestry controls 11,271 European ancestry cases, 14,601 European ancestry controls Affymetrix [745006] 15 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST001565 Genome-wide genotyping array 4646 2012-08-14 22688191 Bergen SE 2012-06-12 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/22688191 Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder. Bipolar disorder and schizophrenia 2,111 European ancestry schizophrenia cases, 836 European ancestry bipolar disorder cases, 2,535 European ancestry controls NA Affymetrix [745006] 13 schizophrenia, bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0000289 GCST001567 Genome-wide genotyping array 5482 2012-08-14 22688191 Bergen SE 2012-06-12 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/22688191 Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder. Bipolar disorder 836 European ancestry cases, 2,093 European ancestry controls NA Affymetrix [745006] 4 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST001569 Genome-wide genotyping array 2929 2012-11-04 22895189 Timmann C 2012-08-15 Nature www.ncbi.nlm.nih.gov/pubmed/22895189 Genome-wide association study indicates two novel resistance loci for severe malaria. Malaria 1,325 African ancestry, 828 African ancestry controls 2,229 African ancestry cases, 3,526 African ancestry controls Affymetrix [4205739] (imputed) 4 malaria http://www.ebi.ac.uk/efo/EFO_0001068 GCST001637 Genome-wide genotyping array 2153 2008-06-18 18471798 Valdes AM 2008-05-08 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/18471798 Genome-wide association scan identifies a prostaglandin-endoperoxide synthase 2 variant involved in risk of knee osteoarthritis. Knee osteoarthritis 357 European ancestry cases, 285 European ancestry controls 1,177 European ancestry cases, 2,372 European ancestry controls Illumina [413461] 2 osteoarthritis, knee http://www.ebi.ac.uk/efo/EFO_0004616 GCST000186 Genome-wide genotyping array 642 2009-09-29 19734903 Lambert JC 2009-09-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19734903 Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Alzheimer's disease 2,032 European ancestry cases, 5,328 European ancestry controls 3,978 European ancestry cases, 3,297 European ancestry controls Illumina [537029] 3 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST000480 Genome-wide genotyping array 7360 2009-07-30 19597491 Gudbjartsson DF 2009-07-13 Nat Genet www.ncbi.nlm.nih.gov/pubmed/19597491 A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke. Atrial fibrillation 2,385 European ancestry cases, 33,752 European ancestry controls up to 2,427 European ancestry cases, 3,379 European ancestry controls, 286 Han Chinese ancestry cases, 2,763 Han Chinese ancestry controls Illumina [303136] 2 atrial fibrillation http://www.ebi.ac.uk/efo/EFO_0000275 GCST000446 Genome-wide genotyping array 36137 2011-01-14 21059979 Shen H 2010-11-08 Arch Intern Med www.ncbi.nlm.nih.gov/pubmed/21059979 Familial defective apolipoprotein B-100 and increased low-density lipoprotein cholesterol and coronary artery calcification in the old order amish. LDL cholesterol 841 Amish individuals 663 Amish inidividuals Affymetrix [369241] 2 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST000866 Genome-wide genotyping array 841 2013-01-11 23118974 Candille SI 2012-10-31 PLoS One www.ncbi.nlm.nih.gov/pubmed/23118974 Genome-wide association studies of quantitatively measured skin, hair, and eye pigmentation in four European populations. Eye color 175 European ancestry individuals 293 European ancestry individuals Illumina [313763] 3 eye color http://www.ebi.ac.uk/efo/EFO_0003949 GCST001723 Genome-wide genotyping array 175 2012-06-20 22538805 Tantisira KG 2012-04-26 Am J Respir Crit Care Med www.ncbi.nlm.nih.gov/pubmed/22538805 Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus. Asthma 418 European ancestry cases 407 European ancestry cases Affymetrix [444088] 1 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST001495 Genome-wide genotyping array 418 2013-09-14 23612905 Zhao SX 2013-04-29 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23612905 Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis. Graves' disease 1,442 Han Chinese ancestry cases, 1,468 Han Chinese ancestry controls 7,891 Han Chinese ancestry cases, 8,351 Han Chinese ancestry controls Illumina [8019905] (imputed) 5 Graves disease http://www.ebi.ac.uk/efo/EFO_0004237 GCST001984 Genome-wide genotyping array 2910 2013-09-14 23612905 Zhao SX 2013-04-29 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23612905 Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis. Graves' disease 1,442 Han Chinese ancestry cases, 1,468 Han Chinese ancestry controls 6,358 Han Chinese ancestry cases, 6,722 Han Chinese ancestry controls Illumina [483947] 1 Graves disease http://www.ebi.ac.uk/efo/EFO_0004237 GCST001982 Genome-wide genotyping array 2910 2010-01-19 20044523 Debette S 2009-12-31 Stroke www.ncbi.nlm.nih.gov/pubmed/20044523 Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium. Subclinical brain infarct 9,401 European ancestry individuals 1,822 European ancestry individuals, 644 Black individuals Affymetrix, Illumina [2217889] (imputed) 0 MRI defined brain infarct http://www.ebi.ac.uk/efo/EFO_0004715 GCST000554 Genome-wide genotyping array 9401 2012-06-18 22437554 Major JM 2012-03-21 J Nutr www.ncbi.nlm.nih.gov/pubmed/22437554 Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men. Response to Vitamin E supplementation 2,112 European ancestry individuals NA Illumina [549989] 8 response to vitamin http://purl.obolibrary.org/obo/GO_0033273 GCST001450 Genome-wide genotyping array 2112 2011-11-30 22028671 Surakka I 2011-10-20 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22028671 A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol. Lipid traits Up to 32,225 European ancestry individuals 11,509 European ancestry individuals, 11,163 individuals Affymetrix, Illumina, Perlegen [~ 2500000] (imputed) 1 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST001289 Genome-wide genotyping array 32225 2013-07-25 23539754 Yamada Y 2013-03-28 J Med Genet www.ncbi.nlm.nih.gov/pubmed/23539754 Identification of chromosome 3q28 and ALPK1 as susceptibility loci for chronic kidney disease in Japanese individuals by a genome-wide association study. Chronic kidney disease 252 Japanese ancestry cases, 249 Japanese ancestry controls 1,100 Japanese ancestry cases, 2,250 Japanese ancestry controls Illumina [297707] 0 chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0003884 GCST001924 Genome-wide genotyping array 501 2011-11-02 21983785 Macgregor S 2011-10-09 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21983785 Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3. Melanoma 2,168 European ancestry cases, 4,387 European ancestry controls 5,193 European ancestry cases, 15,144 European ancestry controls Illumina [5480804] (imputed) 2 melanoma http://www.ebi.ac.uk/efo/EFO_0000756 GCST001266 Genome-wide genotyping array 6555 2011-12-03 22044751 Foster MC 2011-11-01 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/22044751 Heritability and genome-wide association analysis of renal sinus fat accumulation in the Framingham Heart Study. Renal sinus fat 2,809 European ancestry individuals NA Affymetrix [~ 2500000] (imputed) 8 renal sinus adipose tissue measurement http://www.ebi.ac.uk/efo/EFO_0004864 GCST001304 Genome-wide genotyping array 2809 2013-04-11 23300138 He M 2013-01-07 Gut www.ncbi.nlm.nih.gov/pubmed/23300138 A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk. Tumor biomarkers 3,451 Han Chinese ancestry individuals 10,326 Chinese ancestry individuals Affymetrix, Illumina [NR] (imputed) 11 cancer biomarker measurement http://www.ebi.ac.uk/efo/EFO_0005127 GCST001808 Genome-wide genotyping array 3451 2011-11-30 22029572 Simonson MA 2011-10-26 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/22029572 Recent methods for polygenic analysis of genome-wide data implicate an important effect of common variants on cardiovascular disease risk. Cardiovascular disease risk factors 1,772 individuals NA Affymetrix [258891] 0 cardiovascular measurement http://www.ebi.ac.uk/efo/EFO_0004298 GCST001294 Genome-wide genotyping array 1772 2013-04-09 23290196 Hek K 2013-01-02 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/23290196 A genome-wide association study of depressive symptoms. Depression (quantitative trait) up to 34,549 European ancestry individuals up to 16,709 European ancestry individuals Affymetrix, Illumina [2391896] (imputed) 2 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST001802 Genome-wide genotyping array 34549 2010-09-11 20686651 Gudbjartsson DF 2010-07-29 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/20686651 Association of variants at UMOD with chronic kidney disease and kidney stones-role of age and comorbid diseases. Chronic kidney disease and serum creatinine levels 1,689 European ancestry cases, 37,076 European ancestry controls 1,972 European ancestry cases, 6,125 European ancestry controls Illumina [~ 2500000] (imputed) 4 creatinine measurement, chronic kidney disease http://www.ebi.ac.uk/efo/EFO_0004518, http://www.ebi.ac.uk/efo/EFO_0003884 GCST000742 Genome-wide genotyping array 38765 2010-09-07 20662065 Clancy RM 2010-07-26 Arthritis Rheum www.ncbi.nlm.nih.gov/pubmed/20662065 Identification of candidate loci at 6p21 and 21q22 in a genome-wide association study of cardiac manifestations of neonatal lupus. Neonatal lupus 116 European ancestry cases, 3,351 European ancestry controls NA Illumina [346110] 5 neonatal systemic lupus erythematosus http://www.ebi.ac.uk/efo/EFO_0004537 GCST000738 Genome-wide genotyping array 3467 2012-07-13 22544364 Turnbull C 2012-04-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22544364 A genome-wide association study identifies susceptibility loci for Wilms tumor. Wilms tumor 757 European ancestry cases, 1,879 European ancestry controls 1,488 European ancestry cases, 3,851 European ancestry controls Illumina [599255] 7 Nephroblastoma http://www.orpha.net/ORDO/Orphanet_654 GCST001500 Genome-wide genotyping array 2636 2011-11-03 21971053 Takeuchi F 2011-10-05 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/21971053 Genome-wide association study of coronary artery disease in the Japanese. Coronary heart disease 806 Japanese ancestry cases, 1,337 Japanese ancestry controls 3,593 Japanese ancestry cases, 6,335 Japanese ancestry controls Illumina [451382] 3 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST001260 Genome-wide genotyping array 2143 2011-03-01 21248740 Simon-Sanchez J 2011-01-19 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/21248740 Genome-wide association study confirms extant PD risk loci among the Dutch. Parkinson's disease 772 European ancestry cases, 2,024 European ancestry controls NA Illumina [514799] 0 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST000950 Genome-wide genotyping array 2796 2012-06-22 22558097 Milton JN 2012-04-27 PLoS One www.ncbi.nlm.nih.gov/pubmed/22558097 A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia. Cholelithiasis-related traits in sickle cell anemia 905 African American cases 2,152 African American cases Illumina [569615] 1 cholelithiasis, bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004799, http://www.ebi.ac.uk/efo/EFO_0004570 GCST001497 Genome-wide genotyping array 905 2012-04-03 22420046 Stergiakouli E 2012-02-01 Am J Psychiatry www.ncbi.nlm.nih.gov/pubmed/22420046 Investigating the contribution of common genetic variants to the risk and pathogenesis of ADHD. Attention deficit hyperactivity disorder 727 European ancestry children, 5,081 European ancestry individuals 1,142 European ancestry individuals, 896 cases and 2,455 controls from 2,064 trios Illumina [502702] 0 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST001395 Genome-wide genotyping array 5808 2013-06-11 23455637 Iles MM 2013-03-03 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23455637 A variant in FTO shows association with melanoma risk not due to BMI. Melanoma 1,353 European ancestry cases, 3,566 European ancestry controls 12,313 European ancestry cases, Up to 55,667 European ancestry controls Illumina [2600000] (imputed) 1 melanoma http://www.ebi.ac.uk/efo/EFO_0000756 GCST001886 Genome-wide genotyping array 4919 2012-04-20 22451204 Pankratz N 2012-03-01 Ann Neurol www.ncbi.nlm.nih.gov/pubmed/22451204 Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2. Parkinson's disease 4,238 European ancestry cases, 4,239 European ancestry controls 3,738 European ancestry cases, 2,111 European ancestry controls Illumina [2500000] (imputed) 17 Parkinson's disease http://www.ebi.ac.uk/efo/EFO_0002508 GCST001430 Genome-wide genotyping array 8477 2012-04-28 22452962 Kim HC 2012-03-27 Breast Cancer Res www.ncbi.nlm.nih.gov/pubmed/22452962 A genome-wide association study identifies a breast cancer risk variant in ERBB4 at 2q34: results from the Seoul Breast Cancer Study. Breast cancer 2,273 Korean ancestry cases, 2,052 Korean ancestry controls 4,049 Korean ancestry cases, 3,845 Korean ancestry controls Affymetrix [555525] 1 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST001457 Genome-wide genotyping array 4325 2012-07-17 22637743 Wei S 2012-05-27 Carcinogenesis www.ncbi.nlm.nih.gov/pubmed/22637743 Genome-wide gene-environment interaction analysis for asbestos exposure in lung cancer susceptibility. Lung cancer (asbestos exposure interaction) 1,154 European ancestry cases, 1,137 European ancestry controls NA Illumina [307944] 2 lung carcinoma, asbestos exposure measurement http://www.ebi.ac.uk/efo/EFO_0001071, http://www.ebi.ac.uk/efo/EFO_0004806 GCST001543 Genome-wide genotyping array 2291 2012-08-15 22705344 Sobrin L 2012-06-15 Ophthalmology www.ncbi.nlm.nih.gov/pubmed/22705344 Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes. Age-related macular degeneration (choroidal neovascularisation) 1,775 European ancestry choroidal neovascularization cases, 4,134 European ancestry controls 4,515 European and unknown ancestry choroidal neovascularization cases, 15,240 European and unknown ancestry controls Affymetrix, Illumina [6036699] (imputed) 6 wet macular degeneration http://www.ebi.ac.uk/efo/EFO_0004683 GCST001579 Genome-wide genotyping array 5909 2012-08-15 22705344 Sobrin L 2012-06-15 Ophthalmology www.ncbi.nlm.nih.gov/pubmed/22705344 Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes. Age-related macular degeneration (geographic atrophy) 819 European ancestry geographic atrophy cases, 4,134 European ancestry controls NA Affymetrix, Illumina [6036699] (imputed) 9 atrophic macular degeneration http://www.ebi.ac.uk/efo/EFO_1001492 GCST001578 Genome-wide genotyping array 4953 2012-08-30 22705344 Sobrin L 2012-06-15 Ophthalmology www.ncbi.nlm.nih.gov/pubmed/22705344 Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes. Age-related macular degeneration (CNV vs. GA) 1,775 European ancestry choroidal neovascularization cases, 819 European ancestry geographic atrophy cases, 4,515 European and unknown ancestry choroidal neovascularization cases, 868 European and unknown ancestry geographic atrophy cases Affymetrix, Illumina [6036699] (imputed) 1 atrophic macular degeneration, wet macular degeneration http://www.ebi.ac.uk/efo/EFO_1001492, http://www.ebi.ac.uk/efo/EFO_0004683 GCST001577 Genome-wide genotyping array 2594 2013-06-06 23362303 Wu JH 2013-01-29 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/23362303 Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. Palmitic acid (16:0) levels 8,961 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 12 fatty acid measurement http://www.ebi.ac.uk/efo/EFO_0005110 GCST001838 Genome-wide genotyping array 8961 2013-06-06 23362303 Wu JH 2013-01-29 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/23362303 Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. Palmitoleic acid (16:1n-7) levels 8,961 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 15 fatty acid measurement http://www.ebi.ac.uk/efo/EFO_0005110 GCST001841 Genome-wide genotyping array 8961 2013-06-06 23362303 Wu JH 2013-01-29 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/23362303 Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. Stearic acid (18:0) levels 8,961 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 11 fatty acid measurement http://www.ebi.ac.uk/efo/EFO_0005110 GCST001840 Genome-wide genotyping array 8961 2013-06-05 23362303 Wu JH 2013-01-29 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/23362303 Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. Oleic acid (18:1n-9) levels 8,961 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 9 fatty acid measurement http://www.ebi.ac.uk/efo/EFO_0005110 GCST001834 Genome-wide genotyping array 8961 2011-09-08 21829389 Barbalic M 2011-08-04 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21829389 Genome-wide association analysis of incident coronary heart disease (CHD) in African Americans: a short report. Coronary heart disease 362 African American cases, 2,543 African American controls 862 African American female cases, 7,293 African American female controls Affymetrix [NR] 0 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST001190 Genome-wide genotyping array 2905 2012-12-04 23021708 Kerns SL 2012-09-26 Int J Radiat Oncol Biol Phys www.ncbi.nlm.nih.gov/pubmed/23021708 A 2-stage genome-wide association study to identify single nucleotide polymorphisms associated with development of erectile dysfunction following radiation therapy for prostate cancer. Erectile dysfunction and prostate cancer treatment 132 African American, European, Hispanic/Latin American, East Asian and South Asian ancestry cases, 103 African American, European, Hispanic/Latin American, East Asian ancestry and South Asian ancestry controls 128 African American, European, Hispanic/Latin American, East Asian and South Asian ancestry cases, 102 African American, European, Hispanic/Latin American, East Asian and South Asian ancestry controls Affymetrix [614453] 0 response to radiation, prostate carcinoma, erectile dysfunction http://purl.obolibrary.org/obo/GO_0009314, http://www.ebi.ac.uk/efo/EFO_0001663, http://www.ebi.ac.uk/efo/EFO_0004234 GCST001700 Genome-wide genotyping array 235 2014-02-25 23894154 Kohler A 2013-07-26 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/23894154 Genome-wide association study on differentiated thyroid cancer. Thyroid cancer 690 European ancestry cases, 497 European ancestry controls 2,958 European ancestry cases, 3,727 European ancestry controls Illumina [572042] 2 thyroid carcinoma http://www.ebi.ac.uk/efo/EFO_0002892 GCST002102 Genome-wide genotyping array 1187 2011-07-29 21750702 Schosser A 2011-07-05 PLoS One www.ncbi.nlm.nih.gov/pubmed/21750702 Genomewide association scan of suicidal thoughts and behaviour in major depression. Suicidal ideation 2,023 European ancestry major depressive disorder cases 1,531 European ancestry major depressive disorder cases Illumina [532774] 0 lentiform nucleus measurement http://www.ebi.ac.uk/efo/EFO_0004913 GCST001141 Genome-wide genotyping array 2023 2013-01-18 23139255 Butler AM 2012-11-08 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/23139255 Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts. PR interval 13,415 African American individuals NA Affymetrix, Illumina [2845108] (imputed) 8 PR interval http://www.ebi.ac.uk/efo/EFO_0004462 GCST001735 Genome-wide genotyping array 13415 2013-09-27 23666238 Kou I 2013-05-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23666238 Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis. Scoliosis 1,033 Japanese ancestry cases, 1,473 Japanese ancestry controls 1,529 East Asian ancestry cases, 25,675 East Asian ancestry controls, 447 European ancestry cases, 737 European ancestry controls Illumina [465762] 2 scoliosis http://www.ebi.ac.uk/efo/EFO_0004273 GCST002020 Genome-wide genotyping array 2506 2011-09-17 21826061 Davies G 2011-08-09 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/21826061 Genome-wide association studies establish that human intelligence is highly heritable and polygenic. Intelligence 3,511 European ancestry individuals 670 European ancestry individuals Illumina [549692] 0 intelligence http://www.ebi.ac.uk/efo/EFO_0004337 GCST001195 Genome-wide genotyping array 3511 2013-09-12 23535729 Michailidou K 2013-04-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23535729 Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Breast cancer 10,052 European ancestry cases, 12,575 European ancestry controls 45,290 European ancestry cases, 41,880 European ancestry controls Affymetrix, Illumina [~ 2600000] (imputed) 63 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST001937 Genome-wide genotyping array 22627 2012-11-22 23055271 Gregersen PK 2012-07-16 Ann Neurol www.ncbi.nlm.nih.gov/pubmed/23055271 Risk for myasthenia gravis maps to a (151) Pro→Ala change in TNIP1 and to human leukocyte antigen-B*08. Myasthenia gravis 400 European ancestry cases, 5,505 European ancestry controls 249 European ancestry cases, 3,415 European ancestry controls Illumina [274256] 6 immune system disease http://www.ebi.ac.uk/efo/EFO_0000540 GCST001611 Genome-wide genotyping array 5905 2013-09-21 23650146 Tang W 2013-05-05 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/23650146 A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. Venous thromboembolism 1,618 European ancestry cases, 42,881 European ancestry controls 3,231 European ancestry cases, 3,536 European ancestry controls Affymetrix, Illumina [2543885] (imputed) 8 venous thromboembolism http://www.ebi.ac.uk/efo/EFO_0004286 GCST002012 Genome-wide genotyping array 44499 2013-10-18 20152958 Xing C 2010-02-11 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/20152958 A weighted false discovery rate control procedure reveals alleles at FOXA2 that influence fasting glucose levels. Fasting plasma glucose 2,029 African American individuals, 7,428 European ancestry individuals 1,571 African American individuals, 3,825 European ancestry individuals Affymetrix [814004] 1 fasting blood glucose measurement http://www.ebi.ac.uk/efo/EFO_0004465 GCST000591 Genome-wide genotyping array 9457 2013-04-11 22504420 Estrada K 2012-04-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22504420 Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Lumbar spine bone mineral density Up to 32,961 European and East Asian ancestry individuals Up to 50,933 European and East Asian ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 34 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST001482 Genome-wide genotyping array 32961 2019-05-01 22504420 Estrada K 2012-04-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22504420 Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Femoral neck bone mineral density Up to 32,961 European and East Asian ancestry individuals Up to 50,933 European and East Asian ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 35 femoral neck bone mineral density http://www.ebi.ac.uk/efo/EFO_0007785 GCST007691 Genome-wide genotyping array 32961 2011-09-21 21829393 Plagnol V 2011-08-04 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21829393 Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. Type 1 diabetes 8,506 European ancestry cases, up to 10,596 European ancestry controls NA Affymetrix, Illumina [NR] 22 type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001359 GCST001191 Genome-wide genotyping array 19102 2017-07-24 21829393 Plagnol V 2011-08-04 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21829393 Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. Glutamate decarboxylase autoantibody levels in type 1 diabetes 2,506 European ancestry cases NA Affymetrix, Illumina [NR] 0 autoantibody measurement http://www.ebi.ac.uk/efo/EFO_0004866 GCST004380 Genome-wide genotyping array 2506 2017-07-24 21829393 Plagnol V 2011-08-04 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21829393 Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes 2,498 European ancestry cases 3,897 sibling cases Affymetrix, Illumina [NR] 1 autoantibody measurement http://www.ebi.ac.uk/efo/EFO_0004866 GCST004381 Genome-wide genotyping array 2498 2017-07-24 21829393 Plagnol V 2011-08-04 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21829393 Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. Gastric parietal cell autoantibody levels in type 1 diabetes 4,328 European ancestry cases NA Affymetrix, Illumina [NR] 1 autoantibody measurement http://www.ebi.ac.uk/efo/EFO_0004866 GCST004382 Genome-wide genotyping array 4328 2017-07-24 21829393 Plagnol V 2011-08-04 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21829393 Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. Thyroid peroxidase autoantibody levels in type 1 diabetes 8,300 European ancestry cases NA Affymetrix, Illumina [NR] 1 thyroid peroxidase antibody measurement http://www.ebi.ac.uk/efo/EFO_0005666 GCST004383 Genome-wide genotyping array 8300 2013-09-12 23624525 Deng M 2013-04-28 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23624525 Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis 506 Han Chinese ancestry cases, 1,859 Han Chinese ancestry controls 706 Han Chinese ancestry cases, 1,777 Han Chinese ancestry controls Illumina [473683] 2 amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0000253 GCST001981 Genome-wide genotyping array 2365 2012-06-19 22491018 Wang J 2012-04-10 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/22491018 Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis. Response to tocilizumab in rheumatoid arthritis 1,157 European and other ancestry rheumatoid arthritis cases 526 European and other ancestry rheumatoid arthritis cases Illumina [534053] 31 response to drug http://purl.obolibrary.org/obo/GO_0042493 GCST001476 Genome-wide genotyping array 1157 2012-04-28 22497812 Clark PJ 2012-02-22 J Viral Hepat www.ncbi.nlm.nih.gov/pubmed/22497812 Interleukin 28B polymorphisms are the only common genetic variants associated with low-density lipoprotein cholesterol (LDL-C) in genotype-1 chronic hepatitis C and determine the association between LDL-C and treatment response. Lipid levels in hepatitis C treatment 1,017 European ancestry cases, 207 African American cases, 95 Hispanic cases NA Illumina [565759] 1 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST001418 Genome-wide genotyping array 1319 2011-12-21 22131368 Chen CT 2011-11-30 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22131368 Replication of loci influencing ages at menarche and menopause in Hispanic women: the Women's Health Initiative SHARe Study. Menarche and menopause (age at onset) 3,468 Hispanic female individuals NA Affymetrix [871309] 0 age at menarche, age at menopause http://www.ebi.ac.uk/efo/EFO_0004703, http://www.ebi.ac.uk/efo/EFO_0004704 GCST001336 Genome-wide genotyping array 3468 2011-08-03 21750679 Allanore Y 2011-07-07 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21750679 Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis. Systemic sclerosis 564 European ancestry cases, 1,776 European ancestry controls 1,682 European ancestry cases, 3,926 European ancestry controls Illumina [489814] 7 systemic scleroderma http://www.ebi.ac.uk/efo/EFO_0000717 GCST001146 Genome-wide genotyping array 2340 2011-08-15 21779176 Winkelmann J 2011-07-14 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21779176 Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1. Restless legs syndrome 922 European ancestry cases, 1,526 European ancestry controls 3,935 European ancestry cases, 5,754 European ancestry controls Affymetrix [301406] 6 restless legs syndrome http://www.ebi.ac.uk/efo/EFO_0004270 GCST001159 Genome-wide genotyping array 2448 2012-07-27 22566624 Castano Betancourt MC 2012-05-07 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/22566624 Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis. Osteoarthritis 6,523 European ancestry individuals 4,442 European ancestry individuals Illumina [2455290] (imputed) 1 osteoarthritis http://www.ebi.ac.uk/efo/EFO_0002506 GCST001516 Genome-wide genotyping array 6523 2012-03-27 22403646 Froguel P 2012-03-05 PLoS One www.ncbi.nlm.nih.gov/pubmed/22403646 A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels. Haptoglobin levels 631 European ancestry children 2,957 European ancestry family members, 1,434 European ancestry individuals Illumina [318237] 1 haptoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004640 GCST001435 Genome-wide genotyping array 631 2011-05-25 21533074 Smedby KE 2011-04-21 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21533074 GWAS of follicular lymphoma reveals allelic heterogeneity at 6p21.32 and suggests shared genetic susceptibility with diffuse large B-cell lymphoma. Follicular lymphoma 379 European ancestry cases, 791 European ancestry controls 1,049 European ancestry cases, 3,952 European ancestry controls Illumina [298168] 1 neoplasm of mature B-cells http://www.ebi.ac.uk/efo/EFO_0000096 GCST001051 Genome-wide genotyping array 1170 2011-05-27 21570397 Lucena MI 2011-04-12 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/21570397 Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. Drug-induced liver injury (amoxicillin-clavulanate) 201 European ancestry cases, 532 European ancestry controls NA Illumina [822927] 2 drug-induced liver injury http://www.ebi.ac.uk/efo/EFO_0004228 GCST001036 Genome-wide genotyping array 733 2011-12-10 21981779 Denny JC 2011-10-07 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/21981779 Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies. Hypothyroidism 1,317 European ancestry cases, 5,053 European ancestry controls 263 European ancestry cases, 1,616 European ancestry controls Illumina [522164] 1 hypothyroidism http://www.ebi.ac.uk/efo/EFO_0004705 GCST001265 Genome-wide genotyping array 6370 2011-09-28 21878436 Sampietro ML 2011-08-30 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21878436 A genome-wide association study identifies a region at chromosome 12 as a potential susceptibility locus for restenosis after percutaneous coronary intervention. Coronary restenosis 295 European ancestry cases, 571 European ancestry controls 455 European ancestry cases, 2,880 European ancestry controls Illumina [556099] 1 Coronary Restenosis http://www.ebi.ac.uk/efo/EFO_0004224 GCST001214 Genome-wide genotyping array 866 2013-10-31 23668334 Shan J 2013-05-13 J Transl Med www.ncbi.nlm.nih.gov/pubmed/23668334 Genome scan study of prostate cancer in Arabs: identification of three genomic regions with multiple prostate cancer susceptibility loci in Tunisians. Prostate cancer 90 Tunisian ancestry cases, 131 Tunisian ancestry controls 155 Arab ancestry cases, 182 Arab ancestry controls Affymetrix [534781] 0 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST002024 Genome-wide genotyping array 221 2012-07-17 22634755 Dunlop MG 2012-05-27 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22634755 Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk. Colorectal cancer 8,323 European ancestry cases, 9,457 European ancestry controls 19,513 European ancestry cases, 17,657 European ancestry controls, 1,583 Japanese ancestry cases, 1,898 Japanese ancestry controls Illumina [NR] (imputed) 3 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST001544 Genome-wide genotyping array 17780 2012-03-13 22310353 Man M 2012-02-07 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/22310353 Beyond single-marker analyses: mining whole genome scans for insights into treatment responses in severe sepsis. Treatment response for severe sepsis 1,446 individuals NA Illumina [856627] 8 response to drug http://purl.obolibrary.org/obo/GO_0042493 GCST001402 Genome-wide genotyping array 1446 2011-04-13 21424380 Sehrawat B 2011-03-19 Hum Genet www.ncbi.nlm.nih.gov/pubmed/21424380 Potential novel candidate polymorphisms identified in genome-wide association study for breast cancer susceptibility. Breast cancer 302 European ancestry female cases, 321 European ancestry female controls 1,153 European ancestry female cases, 1,215 European ancestry female controls Affymetrix [782838] 2 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST001012 Genome-wide genotyping array 623 2012-08-09 22566560 Malhotra AK 2012-05-07 Arch Gen Psychiatry www.ncbi.nlm.nih.gov/pubmed/22566560 Association between common variants near the melanocortin 4 receptor gene and severe antipsychotic drug-induced weight gain. Antipsychotic drug-induced weight gain 77 European ancestry individuals, 32 African American individuals, 30 individuals 183 European ancestry individuals, 22 African American individuals Illumina [803582] 1 antipsychotic drug related weight gain http://www.ebi.ac.uk/efo/EFO_0004567 GCST001517 Genome-wide genotyping array 139 2014-03-28 24023788 Ong BA 2013-09-02 PLoS One www.ncbi.nlm.nih.gov/pubmed/24023788 Gene network analysis in a pediatric cohort identifies novel lung function genes. Lung function (FEV1) 1,015 European ancestry individuals, 541 African American individuals NA Illumina [up to 524000] 9 forced expiratory volume http://www.ebi.ac.uk/efo/EFO_0004314 GCST002165 Genome-wide genotyping array 1556 2014-03-28 24023788 Ong BA 2013-09-02 PLoS One www.ncbi.nlm.nih.gov/pubmed/24023788 Gene network analysis in a pediatric cohort identifies novel lung function genes. Lung function (FEV1/FVC) 1,015 European ancestry individuals, 541 African American individuals NA Illumina [up to 524000] 5 FEV/FEC ratio http://www.ebi.ac.uk/efo/EFO_0004713 GCST002164 Genome-wide genotyping array 1556 2014-03-28 24023788 Ong BA 2013-09-02 PLoS One www.ncbi.nlm.nih.gov/pubmed/24023788 Gene network analysis in a pediatric cohort identifies novel lung function genes. Lung function (FVC) 1,015 European ancestry individuals, 541 African American individuals NA Illumina [up to 524000] 9 vital capacity http://www.ebi.ac.uk/efo/EFO_0004312 GCST002162 Genome-wide genotyping array 1556 2014-03-28 24023788 Ong BA 2013-09-02 PLoS One www.ncbi.nlm.nih.gov/pubmed/24023788 Gene network analysis in a pediatric cohort identifies novel lung function genes. Lung function (forced expiratory flow during mid-portion (25% and 75%) of forced vital capacity) 1,015 European ancestry individuals, 541 African American individuals NA Illumina [up to 524000] 12 maximal midexpiratory flow rate http://www.ebi.ac.uk/efo/EFO_0004313 GCST002163 Genome-wide genotyping array 1556 2010-08-12 20596022 Petukhova L 2010-07-01 Nature www.ncbi.nlm.nih.gov/pubmed/20596022 Genome-wide association study in alopecia areata implicates both innate and adaptive immunity. Alopecia areata Up to 1,054 European ancestry cases, 3,278 European ancestry controls NA Illumina [463301] 8 alopecia areata http://www.ebi.ac.uk/efo/EFO_0004192 GCST000719 Genome-wide genotyping array 4332 2010-07-12 20585626 Long J 2010-06-24 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/20585626 Identification of a functional genetic variant at 16q12.1 for breast cancer risk: results from the Asia Breast Cancer Consortium. Breast cancer 2,073 Chinese ancestry cases, 2,084 Chinese ancestry controls 15,159 East Asian ancestry cases, 12,993 East Asian ancestry controls, 2,797 European ancestry cases, 2,662 European ancestry controls Affymetrix [684457] 1 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST000709 Genome-wide genotyping array 4157 2011-09-08 21810271 Antoni G 2011-08-02 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/21810271 Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels. vWF and FVIII levels 1,624 European ancestry individuals NA Illumina [442728] 11 coagulation factor measurement http://www.ebi.ac.uk/efo/EFO_0004634 GCST001188 Genome-wide genotyping array 1624 2012-02-09 22267200 Gudmundsson J 2012-01-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22267200 Discovery of common variants associated with low TSH levels and thyroid cancer risk. Thyroid cancer 27,758 European ancestry individuals 1,156 European ancestry cases, up to 42,617 European ancestry controls Illumina [~ 16000000] (imputed) 3 thyroid carcinoma http://www.ebi.ac.uk/efo/EFO_0002892 GCST001382 Genome-wide genotyping array 27758 2011-08-12 21768215 Tin A 2011-07-18 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21768215 Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele. Urate levels 8,651 African American individuals 1,996 African American individuals Affymetrix [NR] (imputed) 5 urate measurement http://www.ebi.ac.uk/efo/EFO_0004531 GCST001163 Genome-wide genotyping array 8651 2014-03-14 23983088 Miller FW 2013-08-27 Arthritis Rheum www.ncbi.nlm.nih.gov/pubmed/23983088 Genome-wide association study of dermatomyositis reveals genetic overlap with other autoimmune disorders. Dermatomyositis 1,178 European ancestry cases, 4,724 European ancestry controls NA Illumina [up to 242876] 1 dermatomyositis http://www.ebi.ac.uk/efo/EFO_0000398 GCST002151 Genome-wide genotyping array 5902 2011-05-11 21478494 Nan H 2011-04-09 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21478494 Genome-wide association study identifies nidogen 1 (NID1) as a susceptibility locus to cutaneous nevi and melanoma risk. Cutaneous nevi 9,136 European ancestry individuals 3,581 European ancestry individuals Affymetrix, Illumina [2318094] (imputed) 3 nevus http://www.ebi.ac.uk/efo/EFO_0000625 GCST001034 Genome-wide genotyping array 9136 2013-04-11 23314186 Crosslin DR 2013-03-03 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23314186 Genetic variation associated with circulating monocyte count in the eMERGE Network. Monocyte count 9,849 European ancestry individuals, 894 African ancestry individuals, 271 individuals NA Illumina [NR] 6 monocyte count http://www.ebi.ac.uk/efo/EFO_0005091 GCST001887 Genome-wide genotyping array 11014 2013-02-27 23237013 Power RA 2012-12-14 Psychol Med www.ncbi.nlm.nih.gov/pubmed/23237013 Estimating the heritability of reporting stressful life events captured by common genetic variants. Reporting of stressful life event 2,578 European ancestry depression cases and controls 864 European ancestry depression cases, 257 European ancestry controls Illumina [541628] 0 self rated health, stressful life event measurement http://www.ebi.ac.uk/efo/EFO_0004778, http://www.ebi.ac.uk/efo/EFO_0007781 GCST001774 Genome-wide genotyping array 2578 2013-09-21 23667675 Tanikawa C 2013-05-07 PLoS One www.ncbi.nlm.nih.gov/pubmed/23667675 Genome wide association study of age at menarche in the Japanese population. Menarche (age at onset) 15,495 Japanese ancestry females NA Illumina [2310762] (imputed) 8 age at menarche http://www.ebi.ac.uk/efo/EFO_0004703 GCST002013 Genome-wide genotyping array 15495 2011-12-15 22072270 Wang KS 2011-11-11 J Neural Transm (Vienna) www.ncbi.nlm.nih.gov/pubmed/22072270 Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms. Alcohol withdrawal symptoms 461 European ancestry cases, 408 European ancestry controls 318 European ancestry cases, 507 European ancestry controls Illumina [778974] 0 alcohol withdrawal http://www.ebi.ac.uk/efo/EFO_0004777 GCST001319 Genome-wide genotyping array 869 2013-05-14 23393555 Jensen RA 2013-02-05 PLoS One www.ncbi.nlm.nih.gov/pubmed/23393555 Genome-wide association study of retinopathy in individuals without diabetes. Retinopathy in non-diabetics 19,411 European ancestry individuals NA Illumina [2675979] (imputed) 11 retinopathy http://www.ebi.ac.uk/efo/EFO_0003839 GCST001854 Genome-wide genotyping array 19411 2013-06-06 23420232 Duggal P 2013-02-19 Ann Intern Med www.ncbi.nlm.nih.gov/pubmed/23420232 Genome-wide association study of spontaneous resolution of hepatitis C virus infection: data from multiple cohorts. Chronic hepatitis C infection 1,482 chronic HCV cases, 919 spontaneously cleared HCV cases 461 chronic HCV cases, 284 spontaneously cleared HCV cases Illumina [792721] (imputed) 2 chronic hepatitis C virus infection http://www.ebi.ac.uk/efo/EFO_0004220 GCST001867 Genome-wide genotyping array 2401 2012-09-20 22797724 Shiraishi K 2012-07-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22797724 A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population. Lung adenocarcinoma 1,695 Japanese ancestry cases, 5,333 Japanese ancestry controls 4,334 Japanese ancestry cases, 8,202 Japanese ancestry controls Illumina [538166] 4 lung adenocarcinoma http://www.ebi.ac.uk/efo/EFO_0000571 GCST001609 Genome-wide genotyping array 7028 2012-09-20 22788528 Kong M 2012-07-13 Int J Immunogenet www.ncbi.nlm.nih.gov/pubmed/22788528 Genetic associations with C-reactive protein level and white blood cell count in the KARE study. C-reactive protein and white blood cell count 8,722 individuals NA Affymetrix [1701735] (imputed) 9 leukocyte count, C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004308, http://www.ebi.ac.uk/efo/EFO_0004458 GCST001605 Genome-wide genotyping array 8722 2013-05-09 23378610 Xie W 2013-02-01 Diabetes www.ncbi.nlm.nih.gov/pubmed/23378610 Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes. Metabolite levels 1,004 European ancestry individuals 339 European ancestry individuals Affymetrix [909508] (imputed) 6 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST001852 Genome-wide genotyping array 1004 2013-07-09 23535734 Codd V 2013-04-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23535734 Identification of seven loci affecting mean telomere length and their association with disease. Telomere length 37,684 European ancestry individuals 10,739 European ancestry individuals Affymetrix, Illumina [2362330] 3 telomere length http://www.ebi.ac.uk/efo/EFO_0004505 GCST001936 Genome-wide genotyping array 37684 2015-05-14 22041458 Clark SL 2011-11-01 Psychol Med www.ncbi.nlm.nih.gov/pubmed/22041458 Pharmacogenomic study of side-effects for antidepressant treatment options in STAR*D. Response to anti-depressant treatment in major depressive disorder 1,151 European ancestry cases, 288 African American cases NA Affymetrix [421789] 22 response to antidepressant http://purl.obolibrary.org/obo/GO_0036276 GCST001308 Genome-wide genotyping array 1439 2011-11-25 22021425 Carty CL 2011-10-21 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22021425 Genome-wide association study of body height in African Americans: the Women's Health Initiative SNP Health Association Resource (SHARe). Height 8,149 African American female individuals Up to 20,809 African American and African ancestry individuals Affymetrix [855034] 8 body height http://www.ebi.ac.uk/efo/EFO_0004339 GCST001290 Genome-wide genotyping array 8149 2012-05-11 22472876 Sullivan PF 2012-04-03 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/22472876 A mega-analysis of genome-wide association studies for major depressive disorder. Major depressive disorder 9,240 European ancestry cases, 9,519 European ancestry controls 6,783 European ancestry cases, 50,695 European ancestry controls Affymetrix, Illumina, Perlegen [~ 1200000] (imputed) 5 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST001469 Genome-wide genotyping array 18759 2012-06-21 22504417 Stein JL 2012-04-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22504417 Identification of common variants associated with human hippocampal and intracranial volumes. Brain structure 2,020 European ancestry neuropsychiatric disorder cases, 5,775 European ancestry controls 599 European ancestry neuropsychiatric disorder cases, 11,915 European ancestry controls, 143 European ancestry and African American neuropsychiatric disorder cases, 94 European ancestry and African American controls, 605 Hispanic controls Affymetrix, Illumina [NR] (imputed) 2 brain measurement http://www.ebi.ac.uk/efo/EFO_0004464 GCST001481 Genome-wide genotyping array 7795 2013-12-05 23749188 Tan DE 2013-06-09 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23749188 Genome-wide association study of B cell non-Hodgkin lymphoma identifies 3q27 as a susceptibility locus in the Chinese population. B cell non-Hodgkin lymphoma 253 Singaporean Chinese ancestry cases, 1,438 Singaporean Chinese ancestry controls 1,175 Han Chinese ancestry cases, 5,492 Han Chinese ancestry controls Illumina [550946] 1 lymphoma http://www.ebi.ac.uk/efo/EFO_0000574 GCST002066 Genome-wide genotyping array 1691 2009-01-06 19065144 Sullivan PF 2008-12-09 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/19065144 Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. Major depressive disorder 1,738 European ancestry cases, 1,802 European ancestry controls 6,079 European ancestry cases, 5,893 European ancestry controls Perlegen [435291] 0 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST000293 Genome-wide genotyping array 3540 2008-11-12 18836448 Franke A 2008-10-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18836448 Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility. Ulcerative colitis 1,167 European ancestry cases, 777 European ancestry controls 1,855 European ancestry cases, 3,091 European ancestry controls Affymetrix [355262] 2 ulcerative colitis http://www.ebi.ac.uk/efo/EFO_0000729 GCST000243 Genome-wide genotyping array 1944 2008-12-09 18802019 Burkhardt R 2008-09-18 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/18802019 Common SNPs in HMGCR in micronesians and whites associated with LDL-cholesterol levels affect alternative splicing of exon13. LDL cholesterol 2,346 Micronesian ancestry individuals NA Affymetrix [~ 500000] 2 low density lipoprotein cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004611 GCST000234 Genome-wide genotyping array 2346 2012-09-26 22821403 Ellinghaus D 2012-07-23 Hepatology www.ncbi.nlm.nih.gov/pubmed/22821403 Genome-wide association analysis in primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4. Sclerosing cholangitis and ulcerative colitis (combined) Up to 389 European ancestry primary sclerosing cholangitis cases, 987 European ancestry ulcerative colitis cases, 2,968 European ancestry controls 1,012 European ancestry primary sclerosing cholangitis cases, 4,444 European ancestry ulcerative colitis cases, 11,659 European ancestry controls Affymetrix [up to 1279891] (imputed) 2 ulcerative colitis, sclerosing cholangitis http://www.ebi.ac.uk/efo/EFO_0000729, http://www.ebi.ac.uk/efo/EFO_0004268 GCST001615 Genome-wide genotyping array 4344 2014-02-04 23853074 Meder B 2013-07-12 Eur Heart J www.ncbi.nlm.nih.gov/pubmed/23853074 A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy. Idiopathic dilated cardiomyopathy 909 European ancestry cases, 2,120 European ancestry controls 3,234 European ancestry cases, 5,590 European ancestry controls Affymetrix [292367] 0 dilated cardiomyopathy http://www.ebi.ac.uk/efo/EFO_0000407 GCST002093 Genome-wide genotyping array 3029 2012-01-20 22188591 Anantharaman R 2011-12-21 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/22188591 Genome-wide association study identifies PERLD1 as asthma candidate gene. Asthma 490 Chinese ancestry cases, 490 Chinese ancestry controls 521 Chinese ancestry cases, 524 Chinese ancestry controls Affymetrix [683349] 0 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST001360 Genome-wide genotyping array 980 2010-11-05 20921969 Aberg K 2010-10-05 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/20921969 Genome-wide association study of antipsychotic-induced QTc interval prolongation. Antipsychotic drug-induced QTc interval prolongation 738 European, African American, Hispanic, and other ancestry Schizophrenia cases NA Affymetrix [492000] 3 response to antipsychotic drug http://purl.obolibrary.org/obo/GO_0097332 GCST000822 Genome-wide genotyping array 738 2010-11-15 20887962 Jee SH 2010-10-08 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/20887962 Adiponectin concentrations: a genome-wide association study. Adiponectin levels 4,001 Korean ancestry individuals 2,304 Korean ancestry individuals Affymetrix [up to 354357] 1 adiponectin measurement http://www.ebi.ac.uk/efo/EFO_0004502 GCST000828 Genome-wide genotyping array 4001 2012-03-27 22359512 Demirkan A 2012-02-16 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22359512 Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. Phospholipid levels (plasma) 4,034 European ancestry individuals NA Illumina [NR] (imputed) 25 phospholipid measurement http://www.ebi.ac.uk/efo/EFO_0004639 GCST001414 Genome-wide genotyping array 4034 2012-03-27 22359512 Demirkan A 2012-02-16 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22359512 Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. Sphingolipid levels 4,034 European ancestry individuals NA Illumina [NR] (imputed) 10 sphingolipid measurement http://www.ebi.ac.uk/efo/EFO_0004622 GCST001413 Genome-wide genotyping array 4034 2011-07-30 21743469 Evans DM 2011-07-10 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21743469 Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Ankylosing spondylitis 3,023 European ancestry cases, 8,779 European ancestry controls 2,111 European ancestry cases, 4,483 European ancestry controls Illumina [2223620] (imputed) 13 ankylosing spondylitis http://www.ebi.ac.uk/efo/EFO_0003898 GCST001149 Genome-wide genotyping array 11802 2011-07-30 21703177 Thompson AJ 2011-05-20 J Hepatol www.ncbi.nlm.nih.gov/pubmed/21703177 Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients. IFN-related cytopenia 984 European ancestry with genotype 1 HCV cases, 201 African American genotype 1 HCV cases, 99 Hispanic genotype 1 HCV cases NA Illumina [565759] 1 chronic hepatitis C virus infection http://www.ebi.ac.uk/efo/EFO_0004220 GCST001076 Genome-wide genotyping array 1287 2014-04-02 24023777 Miyake A 2013-09-04 PLoS One www.ncbi.nlm.nih.gov/pubmed/24023777 Identification of a susceptibility locus for severe adolescent idiopathic scoliosis on chromosome 17q24.3. Adolescent idiopathic scoliosis (severe) 554 Japanese ancestry cases, 1,474 Japanese ancestry controls 839 East Asian ancestry cases, 10,149 East Asian ancestry controls Illumina [455121] 1 adolescent idiopathic scoliosis http://www.ebi.ac.uk/efo/EFO_0005423 GCST002169 Genome-wide genotyping array 2028 2011-10-16 21957438 Meschia JF 2011-09-21 PLoS One www.ncbi.nlm.nih.gov/pubmed/21957438 Genomic risk profiling of ischemic stroke: results of an international genome-wide association meta-analysis. Stroke 1,470 European ancestry cases, 1,932 European ancestry controls NA Illumina [5156597] (imputed) 0 stroke http://www.ebi.ac.uk/efo/EFO_0000712 GCST001243 Genome-wide genotyping array 3402 2010-06-08 20453840 Sanna S 2010-05-09 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20453840 Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis. Multiple sclerosis 882 Sardinian cases, 872 Sardinian controls 1,775 Sardinian cases, 2,005 Sardinian controls Affymetrix [6607266] (imputed) 2 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST000680 Genome-wide genotyping array 1754 2012-03-30 22399142 Jongjaroenprasert W 2012-03-08 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/22399142 A genome-wide association study identifies novel susceptibility genetic variation for thyrotoxic hypokalemic periodic paralysis. Thyrotoxic hypokalemic periodic paralysis 78 Thai ancestry cases, 74 Thai ancestry controls 28 Thai ancestry cases, 48 Thai ancestry controls Illumina [508393] 1 Thyrotoxic periodic paralysis http://www.orpha.net/ORDO/Orphanet_79102 GCST001437 Genome-wide genotyping array 152 2012-03-09 22306650 Thye T 2012-02-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22306650 Common variants at 11p13 are associated with susceptibility to tuberculosis. Tuberculosis 1,329 African ancestry cases, 1,847 African ancestry controls 2,024 African ancestry cases, 5,154 African ancestry controls, 1,025 Indonesian ancestry cases, 983 Indonesian ancestry controls, 4,441 European ancestry cases, 5,874 European ancestry controls Affymetrix [793964] 1 Tuberculosis http://www.orpha.net/ORDO/Orphanet_3389 GCST001398 Genome-wide genotyping array 3176 2011-05-25 21502573 Smith NL 2011-04-21 Circulation www.ncbi.nlm.nih.gov/pubmed/21502573 Genetic predictors of fibrin D-dimer levels in healthy adults. D-dimer levels 21,052 European ancestry individuals NA Affymetrix, Illumina [2522393] (imputed) 15 D dimer measurement http://www.ebi.ac.uk/efo/EFO_0004507 GCST001049 Genome-wide genotyping array 21052 2012-01-27 22216198 Athanasiadis G 2011-12-28 PLoS One www.ncbi.nlm.nih.gov/pubmed/22216198 A genome-wide association study of the Protein C anticoagulant pathway. Anticoagulant levels 397 European ancestry individuals from 21 families NA Illumina [283437] 8 coagulation factor measurement http://www.ebi.ac.uk/efo/EFO_0004634 GCST001365 Genome-wide genotyping array 418 2013-11-14 23648065 Low SK 2013-05-04 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/23648065 Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide) 168 Japanese ancestry cases, 335 Japanese ancestry controls NA Illumina [733202] 3 response to cyclophosphamide, response to antineoplastic agent http://purl.obolibrary.org/obo/GO_1902518, http://purl.obolibrary.org/obo/GO_0097327 GCST002002 Genome-wide genotyping array 503 2013-11-14 23648065 Low SK 2013-05-04 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/23648065 Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs) 371 Japanese ancestry cases, 825 Japanese ancestry controls NA Illumina [733202] 12 response to antineoplastic agent, response to antimicrotubule agent http://purl.obolibrary.org/obo/GO_0097327, http://www.ebi.ac.uk/efo/EFO_0005260 GCST002001 Genome-wide genotyping array 1196 2013-11-14 23648065 Low SK 2013-05-04 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/23648065 Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) 218 Japanese ancestry cases, 364 Japanese controls NA Illumina [733202] 8 response to paclitaxel, response to antineoplastic agent http://purl.obolibrary.org/obo/GO_1901555, http://purl.obolibrary.org/obo/GO_0097327 GCST001999 Genome-wide genotyping array 582 2013-11-14 23648065 Low SK 2013-05-04 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/23648065 Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel) 147 Japanese ancestry cases, 233 Japanese ancestry controls NA Illumina [733202] 7 response to docetaxel, response to antineoplastic agent http://purl.obolibrary.org/obo/GO_1902519, http://purl.obolibrary.org/obo/GO_0097327 GCST001995 Genome-wide genotyping array 380 2013-11-14 23648065 Low SK 2013-05-04 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/23648065 Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors) 106 Japanese ancestry cases, 187 Japanese ancestry controls NA Illumina [733202] 6 response to topoisomerase inhibitor, response to antineoplastic agent http://purl.obolibrary.org/obo/GO_0072758, http://purl.obolibrary.org/obo/GO_0097327 GCST001994 Genome-wide genotyping array 293 2013-11-14 23648065 Low SK 2013-05-04 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/23648065 Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin) 59 Japanese ancestry cases, 155 Japanese ancestry controls NA Illumina [733202] 3 response to camptothecin, response to antineoplastic agent http://purl.obolibrary.org/obo/GO_1901563, http://purl.obolibrary.org/obo/GO_0097327 GCST001993 Genome-wide genotyping array 214 2013-11-14 23648065 Low SK 2013-05-04 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/23648065 Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide) 54 Japanese ancestry cases, 39 Japanese ancestry controls NA Illumina [733202] 4 response to etoposide, response to antineoplastic agent http://purl.obolibrary.org/obo/GO_1902521, http://purl.obolibrary.org/obo/GO_0097327 GCST002000 Genome-wide genotyping array 93 2013-11-14 23648065 Low SK 2013-05-04 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/23648065 Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin) 261 Japanese ancestry cases, 262 Japanese ancestry controls NA Illumina [733202] 9 response to carboplatin, response to antineoplastic agent http://purl.obolibrary.org/obo/GO_0097328, http://purl.obolibrary.org/obo/GO_0097327 GCST002004 Genome-wide genotyping array 523 2013-11-14 23648065 Low SK 2013-05-04 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/23648065 Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs) 294 Japanese ancestry cases, 2,249 Japanese ancestry controls NA Illumina [733202] 6 response to antineoplastic agent, response to antimetabolite http://purl.obolibrary.org/obo/GO_0097327, http://purl.obolibrary.org/obo/GO_0097329 GCST002005 Genome-wide genotyping array 2543 2013-11-14 23648065 Low SK 2013-05-04 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/23648065 Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin) 150 Japanese ancestry cases, 166 Japanese ancestry controls NA Illumina [733202] 7 response to carboplatin, response to paclitaxel, response to antineoplastic agent http://purl.obolibrary.org/obo/GO_0097328, http://purl.obolibrary.org/obo/GO_1901555, http://purl.obolibrary.org/obo/GO_0097327 GCST002006 Genome-wide genotyping array 316 2013-11-14 23648065 Low SK 2013-05-04 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/23648065 Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) 176 Japanese ancestry cases, 471 Japanese ancestry controls NA Illumina [733202] 7 response to cisplatin, response to antineoplastic agent http://purl.obolibrary.org/obo/GO_0072718, http://purl.obolibrary.org/obo/GO_0097327 GCST002007 Genome-wide genotyping array 647 2013-11-14 23648065 Low SK 2013-05-04 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/23648065 Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs) 184 Japanese ancestry cases, 459 Japanese ancestry controls NA Illumina [733202] 6 response to antineoplastic agent, response to anthracycline-based chemotherapy http://purl.obolibrary.org/obo/GO_0097327, http://www.ebi.ac.uk/efo/EFO_0005257 GCST002008 Genome-wide genotyping array 643 2013-11-14 23648065 Low SK 2013-05-04 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/23648065 Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin) 83 Japanese ancestry cases, 66 Japanese ancestry controls NA Illumina [733202] 3 response to antineoplastic agent, response to doxorubicin http://purl.obolibrary.org/obo/GO_0097327, http://purl.obolibrary.org/obo/GO_1902520 GCST002009 Genome-wide genotyping array 149 2013-11-14 23648065 Low SK 2013-05-04 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/23648065 Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin) 83 Japanese ancestry cases, 370 Japanese ancestry controls NA Illumina [733202] 5 response to epirubicin, response to antineoplastic agent http://purl.obolibrary.org/obo/GO_1902522, http://purl.obolibrary.org/obo/GO_0097327 GCST001996 Genome-wide genotyping array 453 2013-11-14 23648065 Low SK 2013-05-04 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/23648065 Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil) 177 Japanese ancestry cases, 952 Japanese ancestry controls NA Illumina [733202] 4 response to 5' fluorouracil, response to antineoplastic agent http://purl.obolibrary.org/obo/GO_0036275, http://purl.obolibrary.org/obo/GO_0097327 GCST001997 Genome-wide genotyping array 1129 2013-11-14 23648065 Low SK 2013-05-04 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/23648065 Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs) 428 Japanese ancestry cases, 743 Japanese ancestry controls NA Illumina [733202] 6 response to platinum based chemotherapy, response to antineoplastic agent http://www.ebi.ac.uk/efo/EFO_0004647, http://purl.obolibrary.org/obo/GO_0097327 GCST001998 Genome-wide genotyping array 1171 2013-11-14 23648065 Low SK 2013-05-04 Cancer Sci www.ncbi.nlm.nih.gov/pubmed/23648065 Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine) 80 Japanese ancestry cases, 226 Japanese ancestry controls NA Illumina [733202] 5 response to gemcitabine, response to antineoplastic agent http://purl.obolibrary.org/obo/GO_0036272, http://purl.obolibrary.org/obo/GO_0097327 GCST002003 Genome-wide genotyping array 306 2014-03-14 23982368 Qi L 2013-08-28 JAMA www.ncbi.nlm.nih.gov/pubmed/23982368 Association between a genetic variant related to glutamic acid metabolism and coronary heart disease in individuals with type 2 diabetes. Cardiovascular heart disease in diabetics 669 European ancestry cases, 1,641 European ancestry controls 848 European ancestry cases, 1,030 European ancestry controls Affymetrix [2543016] 1 cardiovascular disease http://www.ebi.ac.uk/efo/EFO_0000319 GCST002153 Genome-wide genotyping array 2310 2012-06-02 22504421 Bis JC 2012-04-15 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22504421 Common variants at 12q14 and 12q24 are associated with hippocampal volume. Hippocampal volume 9,232 European ancestry individuals 2,318 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 5 hippocampal volume http://www.ebi.ac.uk/efo/EFO_0005035 GCST001485 Genome-wide genotyping array 9232 2012-09-18 22792221 Takamoto M 2012-07-05 PLoS One www.ncbi.nlm.nih.gov/pubmed/22792221 Common variants on chromosome 9p21 are associated with normal tension glaucoma. Glaucoma 286 Japanese ancestry cases, 557 Japanese ancestry controls 334 Japanese ancestry cases, 701 Japanese ancestry controls Affymetrix [531009] 1 glaucoma http://www.ebi.ac.uk/efo/EFO_0000516 GCST001596 Genome-wide genotyping array 843 2012-04-27 22424883 Imboden M 2012-03-15 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/22424883 Genome-wide association study of lung function decline in adults with and without asthma. Pulmonary function decline 1,441 European ancestry asthma cases, 2,677 European ancestry controls 1,160 European ancestry asthma cases, 10,858 European ancestry controls Illumina [~ 2500000] (imputed) 39 forced expiratory volume, FEV/FEC ratio http://www.ebi.ac.uk/efo/EFO_0004314, http://www.ebi.ac.uk/efo/EFO_0004713 GCST001444 Genome-wide genotyping array 4118 2011-01-15 21151127 Melum E 2010-12-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21151127 Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci. Primary sclerosing cholangitis 715 European ancestry cases, 2,962 European ancestry controls 1,025 European ancestry cases, 2,174 European ancestry controls Affymetrix [2466182] (imputed) 2 sclerosing cholangitis http://www.ebi.ac.uk/efo/EFO_0004268 GCST000915 Genome-wide genotyping array 3677 2012-03-08 22318345 Cha PC 2012-02-09 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/22318345 A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population. Gallbladder cancer 41 Japanese ancestry cases, 866 Japanese ancestry controls 30 Japanese ancestry cases, 898 Japanese ancestry controls Illumina [425706] (imputed) 5 gallbladder neoplasm http://www.ebi.ac.uk/efo/EFO_0004606 GCST001404 Genome-wide genotyping array 907 2013-09-20 23644492 Wu C 2013-05-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23644492 Genome-wide association study identifies common variants in SLC39A6 associated with length of survival in esophageal squamous-cell carcinoma. Esophageal squamous cell cancer (length of survival) 1,331 Chinese ancestry cases 1,062 Chinese ancestry individuals Affymetrix [665999] 1 survival time, squamous cell carcinoma, esophageal carcinoma http://www.ebi.ac.uk/efo/EFO_0000714, http://www.ebi.ac.uk/efo/EFO_0000707, http://www.ebi.ac.uk/efo/EFO_0002916 GCST002010 Genome-wide genotyping array 1331 2011-06-23 21666692 Chasman DI 2011-06-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21666692 Genome-wide association study reveals three susceptibility loci for common migraine in the general population. Migraine 5,122 European ancestry cases, 18,108 European ancestry controls 3,831 European ancestry cases, 13,889 European ancestry controls Affymetrix, Illumina [2608509] (imputed) 3 migraine disorder http://www.ebi.ac.uk/efo/EFO_0003821 GCST001105 Genome-wide genotyping array 23230 2011-04-13 21428769 McCormack M 2011-03-24 N Engl J Med www.ncbi.nlm.nih.gov/pubmed/21428769 HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans. Adverse response to carbamazepine 65 European ancestry cases, 3,987 European ancestry controls 80 European ancestry cases, 257 European ancestry controls Illumina [~ 1200000] (imputed) 1 response to anticonvulsant http://purl.obolibrary.org/obo/GO_0036277 GCST001014 Genome-wide genotyping array 4052 2011-11-24 22030708 Menke A 2011-10-26 Neuropsychopharmacology www.ncbi.nlm.nih.gov/pubmed/22030708 Genome-wide association study of antidepressant treatment-emergent suicidal ideation. Suicidal ideation 397 European ancestry depressive disorder cases 501 European ancestry depressive disorder cases Illumina [371335] 0 lentiform nucleus measurement http://www.ebi.ac.uk/efo/EFO_0004913 GCST001296 Genome-wide genotyping array 397 2011-06-07 21602797 Wright FA 2011-05-22 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21602797 Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2. Cystic fibrosis severity 2,317 European ancestry cases, 177 cases 898 European ancestry sibling pair cases, 75 sibling pair cases Illumina [~ 2609000] (imputed) 6 Cystic fibrosis http://www.orpha.net/ORDO/Orphanet_586 GCST001077 Genome-wide genotyping array 2494 2012-08-10 22744181 Hai R 2012-06-29 Sci China Life Sci www.ncbi.nlm.nih.gov/pubmed/22744181 Bivariate genome-wide association study suggests that the DARC gene influences lean body mass and age at menarche. Lean body mass and age at menarche (combined) 801 Han Chinese ancestry female individuals 1,692 European ancestry female individuals Affymetrix [909622] 1 body fat distribution, age at menarche http://www.ebi.ac.uk/efo/EFO_0004341, http://www.ebi.ac.uk/efo/EFO_0004703 GCST001584 Genome-wide genotyping array 801 2011-12-16 22075330 Granada M 2011-11-08 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/22075330 A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study. IgE levels 6,819 European ancestry individuals 7,809 European ancestry indivduals Affymetrix [2540223] (imputed) 11 serum IgE measurement http://www.ebi.ac.uk/efo/EFO_0004579 GCST001316 Genome-wide genotyping array 6819 2013-02-06 23146381 Levin AM 2012-11-10 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/23146381 A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations. IgE levels 2,469 African American individuals, 259 Latino individuals, 1,564 European ancestry individuals 2,961 African American individuals, 1,477 Latino individuals, 649 European ancestry individuals, 680 Hutterite individuals Affymetrix, Illumina [NR] (imputed) 4 serum IgE measurement http://www.ebi.ac.uk/efo/EFO_0004579 GCST001739 Genome-wide genotyping array 4292 2012-10-09 22885925 Shi Y 2012-08-12 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22885925 Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome. Polycystic ovary syndrome 2,254 Han Chinese ancestry cases, 3,001 Han Chinese ancestry controls 8,226 Han Chinese ancestry cases, 7,578 Han Chinese ancestry controls Affymetrix [NR] (imputed) 11 polycystic ovary syndrome http://www.ebi.ac.uk/efo/EFO_0000660 GCST001634 Genome-wide genotyping array 5255 2014-02-25 23910658 McRae JF 2013-07-31 Curr Biol www.ncbi.nlm.nih.gov/pubmed/23910658 Identification of regions associated with variation in sensitivity to food-related odors in the human genome. Odorant perception (isobutyraldehyde) 187 European ancestry individuals Up to 109 Asian ancestry indiviudals Affymetrix [619656] 1 sensory perception of smell http://purl.obolibrary.org/obo/GO_0007608 GCST002105 Genome-wide genotyping array 187 2014-02-21 23910658 McRae JF 2013-07-31 Curr Biol www.ncbi.nlm.nih.gov/pubmed/23910658 Identification of regions associated with variation in sensitivity to food-related odors in the human genome. Odorant perception (β-damascenone) 187 European ancestry individuals 89 European ancestry individuals Affymetrix [619656] 1 sensory perception of smell http://purl.obolibrary.org/obo/GO_0007608 GCST002106 Genome-wide genotyping array 187 2015-04-14 23910658 McRae JF 2013-07-31 Curr Biol www.ncbi.nlm.nih.gov/pubmed/23910658 Identification of regions associated with variation in sensitivity to food-related odors in the human genome. Odorant perception (β-ionone) 187 European ancestry individuals Up to 109 Asian ancestry individuals Affymetrix [619656] 1 sensory perception of smell http://purl.obolibrary.org/obo/GO_0007608 GCST002107 Genome-wide genotyping array 187 2013-06-13 23472185 Mero IL 2013-03-05 PLoS One www.ncbi.nlm.nih.gov/pubmed/23472185 Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles. Multiple sclerosis (OCB status) 1,367 European ancestry OCB positive cases, 161 European ancestry OCB negative cases, 428 European ancestry controls NA Illumina [495970] 8 multiple sclerosis, oligoclonal band measurement http://www.ebi.ac.uk/efo/EFO_0003885, http://www.ebi.ac.uk/efo/EFO_0005206 GCST001892 Genome-wide genotyping array 1956 2013-06-13 23472185 Mero IL 2013-03-05 PLoS One www.ncbi.nlm.nih.gov/pubmed/23472185 Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles. Multiple sclerosis (OCB status) 1,367 European ancestry OCB positive cases, 161 European ancestry OCB negative cases 3,029 European ancestry OCB positive cases, 374 European ancestry OCB negative cases Illumina [495970] 3 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST001891 Genome-wide genotyping array 1528 2008-12-09 18976728 Bertram L 2008-10-29 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/18976728 Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. Alzheimer's disease 941 European ancestry cases and 404 European ancestry controls from 410 families 1,767 European ancestry cases and 838 European ancestry controls from 875 families Affymetrix [484522] 2 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST000255 Genome-wide genotyping array 1755 2008-12-01 18980221 Neale BM 2008-11-03 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/18980221 Genome-wide association scan of attention deficit hyperactivity disorder. Attention deficit hyperactivity disorder 909 European ancestry trios NA Perlegen [438784] 0 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST000259 Genome-wide genotyping array 909 2011-06-25 21659360 Wade R 2011-06-09 Haematologica www.ncbi.nlm.nih.gov/pubmed/21659360 Association between single nucleotide polymorphism-genotype and outcome of patients with chronic lymphocytic leukemia in a randomized chemotherapy trial. Response to antineoplastic agents 356 European ancestry cases 380 European ancestry cases Illumina [326385] 9 response to antineoplastic agent http://purl.obolibrary.org/obo/GO_0097327 GCST001095 Genome-wide genotyping array 356 2013-06-13 23463857 Ritchie MD 2013-03-05 Circulation www.ncbi.nlm.nih.gov/pubmed/23463857 Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk. Electrocardiographic conduction measures 5,272 European ancestry indiviudals 40,407 European ancestry individuals Illumina [528508] 5 QRS duration http://www.ebi.ac.uk/efo/EFO_0005055 GCST001893 Genome-wide genotyping array 5272 2008-06-16 18264097 Eeles RA 2008-02-10 Nat Genet www.ncbi.nlm.nih.gov/pubmed/18264097 Multiple newly identified loci associated with prostate cancer susceptibility. Prostate cancer 1,854 European ancestry cases, 1,894 European ancestry controls 3,268 European ancestry cases, 3,366 European ancestry controls Illumina [541129] 12 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST000152 Genome-wide genotyping array 3748 2011-11-16 22003152 Grallert H 2011-10-14 Eur Heart J www.ncbi.nlm.nih.gov/pubmed/22003152 Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies. Lipoprotein-associated phospholipase A2 activity and mass 12,126 European ancestry individuals, 1,538 individuals NA Affymetrix, Illumina [2661766] (imputed) 7 lipoprotein-associated phospholipase A(2) measurement http://www.ebi.ac.uk/efo/EFO_0004746 GCST001273 Genome-wide genotyping array 13664 2011-12-08 22010049 Middelberg RP 2011-11-01 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22010049 Loci affecting gamma-glutamyl transferase in adults and adolescents show age × SNP interaction and cardiometabolic disease associations. Gamma glutamyl transferase levels 12,526 European ancestry individuals NA Illumina [2380486] (imputed) 4 serum gamma-glutamyl transferase measurement http://www.ebi.ac.uk/efo/EFO_0004532 GCST001307 Genome-wide genotyping array 12526 2015-05-11 22037903 Crosslin DR 2011-10-30 Hum Genet www.ncbi.nlm.nih.gov/pubmed/22037903 Genetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network. White blood cell count 12,046 European ancestry individuals, 1,487 African ancestry individuals NA Illumina [532566] 4 leukocyte count http://www.ebi.ac.uk/efo/EFO_0004308 GCST001302 Genome-wide genotyping array 13533 2014-02-04 23857890 Power RA 2013-07-15 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/23857890 Genome-wide association analysis accounting for environmental factors through propensity-score matching: application to stressful live events in major depressive disorder. Major depressive disorder 805 European ancestry cases, 805 European ancestry controls NA Illumina [457670] 2 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST002095 Genome-wide genotyping array 1610 2014-03-15 24009623 Jiang J 2013-08-30 Front Genet www.ncbi.nlm.nih.gov/pubmed/24009623 Genome-wide association study for biomarker identification of Rapamycin and Everolimus using a lymphoblastoid cell line system. Response to mTOR inhibitor (everolimus) 87 European ancestry individuals, 91 African American individuals, 94 Han Chinese ancestry individuals NA Affymetrix, Illumina [1348798] 8 response to mTOR inhibitor http://www.ebi.ac.uk/efo/EFO_0005417 GCST002157 Genome-wide genotyping array 272 2014-03-15 24009623 Jiang J 2013-08-30 Front Genet www.ncbi.nlm.nih.gov/pubmed/24009623 Genome-wide association study for biomarker identification of Rapamycin and Everolimus using a lymphoblastoid cell line system. Response to mTOR inhibitor (rapamycin) 87 European ancestry individuals, 91 African American individuals, 94 Han Chinese ancestry individuals NA Affymetrix, Illumina [1348798] 5 response to mTOR inhibitor http://www.ebi.ac.uk/efo/EFO_0005417 GCST002156 Genome-wide genotyping array 272 2013-08-07 23572186 Zheng HF 2013-04-09 J Med Genet www.ncbi.nlm.nih.gov/pubmed/23572186 Meta-analysis of genome-wide studies identifies MEF2C SNPs associated with bone mineral density at forearm. Bone mineral density 5,866 European ancestry individuals 715 Mexican American individuals Illumina [NR] (imputed) 1 bone density http://www.ebi.ac.uk/efo/EFO_0003923 GCST001962 Genome-wide genotyping array 5866 2012-01-06 22142827 Innocenti F 2011-12-05 Clin Cancer Res www.ncbi.nlm.nih.gov/pubmed/22142827 A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303. Response to gemcitabine in pancreatic cancer 294 European ancestry cases NA Illumina [330690] 3 response to gemcitabine http://purl.obolibrary.org/obo/GO_0036272 GCST001346 Genome-wide genotyping array 294 2012-06-22 22605921 Gibson J 2012-04-28 Mol Vis www.ncbi.nlm.nih.gov/pubmed/22605921 Genome-wide association study of primary open angle glaucoma risk and quantitative traits. Glaucoma (primary open-angle) 387 European ancestry cases, 5,380 European ancestry controls 294 European ancestry cases, 50 European ancestry controls Affymetrix [681552] 0 open-angle glaucoma http://www.ebi.ac.uk/efo/EFO_0004190 GCST001498 Genome-wide genotyping array 5767 2012-08-08 22745674 Hager J 2012-06-20 PLoS One www.ncbi.nlm.nih.gov/pubmed/22745674 Genome-wide association study in a Lebanese cohort confirms PHACTR1 as a major determinant of coronary artery stenosis. Coronary heart disease 1,949 Middle Eastern ancestry individuals 2,547 Middle Eastern ancestry individuals Illumina [513079] 3 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST001581 Genome-wide genotyping array 1949 2008-06-22 18521091 Volpi S 2008-06-03 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/18521091 Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia. Response to iloperidone treatment (QT prolongation) 91 African American Schizophrenia cases, 69 European ancestry Schizophrenia cases, 16 Asian ancestry Schizophrenia cases, 7 Schizophrenia cases NA Affymetrix [339272] 6 response to iloperidone http://purl.obolibrary.org/obo/GO_0036287 GCST000201 Genome-wide genotyping array 183 2012-06-18 22613542 Chen XD 2012-03-01 Chin Med J (Engl) www.ncbi.nlm.nih.gov/pubmed/22613542 ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior. Drinking behavior 904 European ancestry individuals 1,972 European ancestry individuals from 593 families, 761 European ancestry individuals, 2,955 Han Chinese ancestry individuals Affymetrix [379319] 0 drinking behavior http://www.ebi.ac.uk/efo/EFO_0004315 GCST001429 Genome-wide genotyping array 904 2013-02-19 23266556 Peters U 2012-12-21 Gastroenterology www.ncbi.nlm.nih.gov/pubmed/23266556 Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. Colorectal cancer 12,696 European ancestry colorectal tumor cases, 15,113 European ancestry controls 958 European ancestry colorectal tumor cases, 909 European ancestry controls, up to 2,098 East Asian ancestry colorectal tumor cases, up to 5,749 East Asian ancestry controls Affymetrix, Illumina [2708280] (imputed) 15 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST001787 Genome-wide genotyping array 27809 2013-02-26 23259602 Wang X 2012-12-21 BMC Oral Health www.ncbi.nlm.nih.gov/pubmed/23259602 Genome-wide association scan of dental caries in the permanent dentition. Dental caries 1,483 European ancestry comparatively younger individuals, 5,960 European ancestry comparatively older individuals NA Affymetrix, Illumina [~ 1400000] (imputed) 34 dental caries http://www.ebi.ac.uk/efo/EFO_0003819 GCST001786 Genome-wide genotyping array 7443 2011-07-20 21706340 Teerlink C 2011-06-26 Hum Genet www.ncbi.nlm.nih.gov/pubmed/21706340 A unique genome-wide association analysis in extended Utah high-risk pedigrees identifies a novel melanoma risk variant on chromosome arm 10q. Melanoma 156 European ancestry cases from 34 high-risk families, 2,150 European ancestry controls NA Illumina [491227] 1 melanoma http://www.ebi.ac.uk/efo/EFO_0000756 GCST001129 Genome-wide genotyping array 2340 2012-10-16 22864933 O'Donnell PH 2012-01-03 Cancer www.ncbi.nlm.nih.gov/pubmed/22864933 Identification of novel germline polymorphisms governing capecitabine sensitivity. Capecitabine sensitivity Up to 84 East Asian ancestry lymphoblastoid cell lines, up to 164 European ancestry lymphoblastoid cell lines, up to 173 African ancestry lymphoblastoid cell lines, up to 82 African American lymphoblastoid cell lines NA NR [~ 2000000] 22 response to antineoplastic agent http://purl.obolibrary.org/obo/GO_0097327 GCST001368 Genome-wide genotyping array 503 2012-03-03 22322875 Kim SJ 2012-02-09 Circ J www.ncbi.nlm.nih.gov/pubmed/22322875 Genetic association of short sleep duration with hypertension incidence--a 6-year follow-up in the Korean genome and epidemiology study. Hypertension risk in short sleep duration 4,965 Korean ancestry individuals NA Affymetrix [334750] 3 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST001405 Genome-wide genotyping array 4965 2012-03-13 22333899 Wei WH 2012-02-15 Eur J Hum Genet www.ncbi.nlm.nih.gov/pubmed/22333899 Genome-wide analysis of epistasis in body mass index using multiple human populations. Body mass index (SNP x SNP interaction) 3,653 European ancestry individuals 5,071 European ancestry individuals Illumina [NR] 0 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST001409 Genome-wide genotyping array 3653 2011-01-04 21094521 Wan YI 2010-11-10 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/21094521 A genome-wide association study to identify genetic determinants of atopy in subjects from the United Kingdom. Atopy 1,083 European ancestry cases, 2,770 European ancestry controls Up to 1,058 European ancestry cases, 2,254 European ancestry controls Illumina [459334] 0 atopy http://www.ebi.ac.uk/efo/EFO_0002686 GCST000870 Genome-wide genotyping array 3853 2013-06-26 23535033 Sherva R 2013-03-24 Alzheimers Dement www.ncbi.nlm.nih.gov/pubmed/23535033 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. Alzheimer's disease (cognitive decline) 303 European ancestry cases NA Illumina [NR] (imputed) 44 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST001915 Genome-wide genotyping array 303 2012-03-30 22377092 Wang KS 2012-02-27 Drug Alcohol Depend www.ncbi.nlm.nih.gov/pubmed/22377092 ANAPC1 and SLCO3A1 are associated with nicotine dependence: meta-analysis of genome-wide association studies. Nicotine dependence 1,079 European ancestry cases, 1,341 European ancestry controls 1,419 European ancestry cases, 1,885 European ancestry controls from 778 nuclear families Illumina [818866] 0 nicotine dependence http://www.ebi.ac.uk/efo/EFO_0003768 GCST001427 Genome-wide genotyping array 2420 2012-04-24 22455414 Tekola Ayele F 2012-03-29 N Engl J Med www.ncbi.nlm.nih.gov/pubmed/22455414 HLA class II locus and susceptibility to podoconiosis. Podoconiosis 194 African ancestry cases, 203 African ancestry controls 202 African ancestry family trios Illumina [551840] 0 podoconiosis http://www.ebi.ac.uk/efo/EFO_0004712 GCST001464 Genome-wide genotyping array 397 2012-05-02 22470424 Kwee LC 2012-03-28 PLoS One www.ncbi.nlm.nih.gov/pubmed/22470424 A high-density genome-wide association screen of sporadic ALS in US veterans. Amyotrophic lateral sclerosis Up to 639 European ancestry cases, 6,257 European ancestry controls Up to 183 European ancestry cases, 961 European ancestry controls Affymetrix, Illumina [1280579] 2 amyotrophic lateral sclerosis http://www.ebi.ac.uk/efo/EFO_0000253 GCST001460 Genome-wide genotyping array 6896 2012-04-06 22417934 Athanasiu L 2012-03-12 Psychiatry Res www.ncbi.nlm.nih.gov/pubmed/22417934 Genome-wide association study identifies genetic loci associated with body mass index and high density lipoprotein-cholesterol levels during psychopharmacological treatment - a cross-sectional naturalistic study. Body mass index and cholesterol (psychopharmacological treatment) 283 European ancestry schizophrenia cases, 213 European ancestry bipolar disorder cases, 98 European ancestry psychosis cases NA Affymetrix [608239] 2 total cholesterol measurement, response to drug, body mass index http://www.ebi.ac.uk/efo/EFO_0004574, http://purl.obolibrary.org/obo/GO_0042493, http://www.ebi.ac.uk/efo/EFO_0004340 GCST001440 Genome-wide genotyping array 594 2012-05-11 22492993 Doumatey AP 2012-04-05 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22492993 C-reactive protein (CRP) promoter polymorphisms influence circulating CRP levels in a genome-wide association study of African Americans. C-reactive protein 837 African American individuals 486 West African ancestry individuals Affymetrix [2366856] (imputed) 1 C-reactive protein measurement http://www.ebi.ac.uk/efo/EFO_0004458 GCST001472 Genome-wide genotyping array 837 2012-01-24 22197929 Yu XQ 2011-12-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22197929 A genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy. IgA nephropathy 1,434 Han Chinese ancestry cases, 4,270 Han Chinese ancestry controls 2,703 Han Chinese ancestry cases, 3,464 Han Chinese ancestry controls Illumina [444882] 9 IGA glomerulonephritis http://www.ebi.ac.uk/efo/EFO_0004194 GCST001364 Genome-wide genotyping array 5704 2011-01-04 21051773 Scerri TS 2010-11-09 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21051773 PCSK6 is associated with handedness in individuals with dyslexia. Handedness in dyslexia 192 individuals 573 European ancestry individuals Illumina [~ 2000000] (imputed) 1 handedness http://www.ebi.ac.uk/efo/EFO_0009902 GCST000868 Genome-wide genotyping array 192 2013-12-11 23760081 Kim YJ 2013-06-10 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23760081 A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. Chronic hepatitis B infection 400 Korean ancestry cases, 1,000 Korean ancestry controls 971 Korean ancestry cases, 1,938 Korean ancestry controls Illumina [719265] 6 chronic hepatitis B virus infection http://www.ebi.ac.uk/efo/EFO_0004239 GCST002068 Genome-wide genotyping array 1400 2015-04-28 22666496 Shiffman D 2012-05-30 PLoS One www.ncbi.nlm.nih.gov/pubmed/22666496 Genome-wide study of gene variants associated with differential cardiovascular event reduction by pravastatin therapy. Coronary heart disease event reduction (statin therapy interaction) 682 European, African American, Hispanic, Asian, Pacific Islander and other ancestry cases with events, 383 cases with events 29 European, African American, Hispanic, Asian, Pacific Islander and other ancestry cases with events, 2,398 European, African American, Hispanic, Asian, Pacific Islander and other ancestry cases without events, 729 cases with events, 9,563 cases without events Illumina [~ 1400000] 1 response to statin, coronary artery disease http://purl.obolibrary.org/obo/GO_0036273, http://www.ebi.ac.uk/efo/EFO_0001645 GCST001545 Genome-wide genotyping array 1065 2011-09-30 21900290 Qi Q 2011-09-06 Eur Heart J www.ncbi.nlm.nih.gov/pubmed/21900290 Genetic variants, plasma lipoprotein(a) levels, and risk of cardiovascular morbidity and mortality among two prospective cohorts of type 2 diabetes. Lp (a) levels 1,450 European ancestry individuals NA Illumina [~ 2500000] (imputed) 4 apolipoprotein A 1 measurement http://www.ebi.ac.uk/efo/EFO_0004614 GCST001218 Genome-wide genotyping array 1450 2011-08-27 21804548 Hirota T 2011-07-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21804548 Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. Asthma 1,532 Japanese ancestry cases, 3,304 Japanese ancestry controls 5,639 Japanese ancestry cases, 24,608 Japanese ancestry controls Illumina [458847] 14 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST001183 Genome-wide genotyping array 4836 2011-09-17 21844665 Hu HJ 2011-08-16 Exp Mol Med www.ncbi.nlm.nih.gov/pubmed/21844665 Common variants at the promoter region of the APOM confer a risk of rheumatoid arthritis. Rheumatoid arthritis 100 Korean ancestry cases, 600 Korean ancestry controls 578 Korean ancestry cases, 711 Korean ancestry controls Affymetrix [300909] 1 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST001203 Genome-wide genotyping array 700 2010-04-14 20339536 Barber MJ 2010-03-22 PLoS One www.ncbi.nlm.nih.gov/pubmed/20339536 Genome-wide association of lipid-lowering response to statins in combined study populations. Response to statin therapy 3,928 European ancestry individuals NA Illumina [~ 2500000] (imputed) 36 response to statin http://purl.obolibrary.org/obo/GO_0036273 GCST000635 Genome-wide genotyping array 3928 2010-04-27 20370913 Ma L 2010-04-06 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/20370913 Genome-wide association analysis of total cholesterol and high-density lipoprotein cholesterol levels using the Framingham heart study data. Cholesterol 6,078 individuals 1,231 European ancestry individuals NR [432096] 0 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST000647 Genome-wide genotyping array 6078 2013-08-06 23509962 Greliche N 2013-03-20 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/23509962 A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosis. Venous thromboembolism (SNP x SNP interaction) 411 European ancestry cases, 1,228 European ancestry controls 1,542 European ancestry cases, 1,110 European ancestry controls Illumina [291872] 37 venous thromboembolism http://www.ebi.ac.uk/efo/EFO_0004286 GCST001913 Genome-wide genotyping array 1639 2013-03-27 23291587 Kirino Y 2013-01-06 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23291587 Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1. Behcet's disease 435 Turkish uveitis cases, 780 Turkish without uveitis cases, 1,278 Turkish controls 355 Turkish uveitis cases, 483 Turkish without uveitis cases, 601 Turkish controls, up to 612 Japanese ancestry cases, up to 740 Japanese ancestry controls Illumina [779465] (imputed) 6 Behcet's syndrome http://www.ebi.ac.uk/efo/EFO_0003780 GCST001804 Genome-wide genotyping array 2493 2012-04-03 22423221 Qayyum R 2012-03-08 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22423221 A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans. Mean platelet volume 16,388 African American individuals NA Affymetrix, Illumina [~ 2200000] (imputed) 3 mean platelet volume http://www.ebi.ac.uk/efo/EFO_0004584 GCST001439 Genome-wide genotyping array 16388 2019-07-02 22423221 Qayyum R 2012-03-08 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22423221 A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans. Platelet count 16,388 African American individuals NA Affymetrix, Illumina [~ 2200000] (imputed) 10 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST008047 Genome-wide genotyping array 16388 2012-12-21 23043469 Menzel S 2012-10-09 Br J Haematol www.ncbi.nlm.nih.gov/pubmed/23043469 HbA2 levels in normal adults are influenced by two distinct genetic mechanisms. HbA2 levels 2,322 European ancestry individuals 1,716 European ancestry individuals Illumina [531038] 2 hemoglobin A2 measurement http://www.ebi.ac.uk/efo/EFO_0005845 GCST001710 Genome-wide genotyping array 2322 2012-07-19 22648509 Wang KS 2012-05-31 J Mol Neurosci www.ncbi.nlm.nih.gov/pubmed/22648509 PKNOX2 is associated with formal thought disorder in schizophrenia: a meta-analysis of two genome-wide association studies. Formal thought disorder in schizophrenia 835 European ancestry cases, 2,694 European ancestry controls NA Affymetrix [729454] 5 formal thought disorder http://www.ebi.ac.uk/efo/EFO_0004805 GCST001549 Genome-wide genotyping array 3529 2013-08-28 23592221 Rahmani M 2013-04-16 Hum Reprod www.ncbi.nlm.nih.gov/pubmed/23592221 Shared genetic factors for age at natural menopause in Iranian and European women. Menopause (age at onset) 165 Iranian ancestry early menopause females, 187 Iranian ancestry late menopause females 573 Iranian ancestry females, 38,968 European ancestry females Illumina [694326] 0 age at menopause http://www.ebi.ac.uk/efo/EFO_0004704 GCST001970 Genome-wide genotyping array 352 2012-05-23 22466613 Sun L 2012-04-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22466613 Multiple apical plasma membrane constituents are associated with susceptibility to meconium ileus in individuals with cystic fibrosis. Cystic fibrosis (meconium ileus) 3,763 European ancestry cases 2,372 European ancestry cases Illumina [7245292] (imputed) 0 cystic fibrosis associated meconium ileus http://www.ebi.ac.uk/efo/EFO_0004608 GCST001468 Genome-wide genotyping array 3763 2012-08-15 22693459 Li R 2012-05-31 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22693459 Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases. Male-pattern baldness 3,891 European ancestry cases, 8,915 European ancestry controls NA Affymetrix, Illumina [2391230] (imputed) 8 androgenetic alopecia http://www.ebi.ac.uk/efo/EFO_0004191 GCST001548 Genome-wide genotyping array 12806 2012-05-25 22503698 Bhatnagar R 2012-04-12 Oral Oncol www.ncbi.nlm.nih.gov/pubmed/22503698 Genome-wide disease association study in chewing tobacco associated oral cancers. Oral cancers (chewing tobacco related) 55 South Asian ancestry cases, 92 South Asian ancestry controls NA Illumina [316018] 0 matrix metalloproteinase measurement, mouth neoplasm http://www.ebi.ac.uk/efo/EFO_0004744, http://www.ebi.ac.uk/efo/EFO_0003868 GCST001480 Genome-wide genotyping array 147 2012-05-25 22509378 Burri A 2012-04-11 PLoS One www.ncbi.nlm.nih.gov/pubmed/22509378 A genome-wide association study of female sexual dysfunction. Sexual dysfunction (female) 1,104 European ancestry twins NA Illumina [2287762] (imputed) 3 sexual dysfunction http://www.ebi.ac.uk/efo/EFO_0004714 GCST001477 Genome-wide genotyping array 1104 2011-09-08 21799462 Srinivasan Y 2011-07-27 Pharmacogenet Genomics www.ncbi.nlm.nih.gov/pubmed/21799462 Genome-wide association study of epirubicin-induced leukopenia in Japanese patients. Epirubicin-induced leukopenia 67 Japanese ancestry cases, 203 Japanese ancestry controls 48 Japanese ancestry cases Illumina [478359] 2 leukopenia http://www.ebi.ac.uk/efo/EFO_0004233 GCST001175 Genome-wide genotyping array 270 2011-08-12 21757653 Lovely RS 2011-07-14 Arterioscler Thromb Vasc Biol www.ncbi.nlm.nih.gov/pubmed/21757653 Assessment of genetic determinants of the association of γ' fibrinogen in relation to cardiovascular disease. Fibrinogen 3,042 individuals NA Affymetrix [~ 2500000] (imputed) 5 fibrinogen measurement http://www.ebi.ac.uk/efo/EFO_0004623 GCST001158 Genome-wide genotyping array 3042 2015-05-06 22791750 Chen G 2012-07-12 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22791750 Genome-wide association study identifies novel loci association with fasting insulin and insulin resistance in African Americans. Insulin-related traits 927 African American non-diabetic individuals 570 West African ancestry non-diabetic individuals Affymetrix [5396838] (imputed) 6 insulin measurement http://www.ebi.ac.uk/efo/EFO_0004467 GCST001604 Genome-wide genotyping array 927 2012-09-12 22792082 Himes BE 2012-07-05 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22792082 Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene. Asthma (bronchodilator response) 1,644 European ancestry cases 1,051 European ancestry cases Affymetrix, Illumina [4571615] (imputed) 1 response to bronchodilator http://purl.obolibrary.org/obo/GO_0097366 GCST001597 Genome-wide genotyping array 1644 2011-01-10 21149285 Ozeki T 2010-12-10 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21149285 Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population. Adverse response to carbamazepine 53 Japanese ancestry cases, 881 Japanese ancestry controls 23 Japanese ancestry cases, 44 Japanese ancestry controls Illumina [444823] 1 response to anticonvulsant http://purl.obolibrary.org/obo/GO_0036277 GCST000912 Genome-wide genotyping array 934 2011-06-16 21626137 Slavin TP 2011-05-28 Hum Genet www.ncbi.nlm.nih.gov/pubmed/21626137 Two-marker association tests yield new disease associations for coronary artery disease and hypertension. Hypertension (SNP x SNP interaction) ~2,000 European ancestry cases, ~3,000 European ancestry controls NA Affymetrix [405022] 9 hypertension http://www.ebi.ac.uk/efo/EFO_0000537 GCST001085 Genome-wide genotyping array 5000 2011-06-16 21626137 Slavin TP 2011-05-28 Hum Genet www.ncbi.nlm.nih.gov/pubmed/21626137 Two-marker association tests yield new disease associations for coronary artery disease and hypertension. Coronary heart disease (SNP X SNP interaction) ~2,000 European ancestry cases, ~3,000 European ancestry controls NA Affymetrix [407576] 5 coronary artery disease http://www.ebi.ac.uk/efo/EFO_0001645 GCST001084 Genome-wide genotyping array 5000 2011-06-14 21621269 Aragam N 2011-05-26 J Affect Disord www.ncbi.nlm.nih.gov/pubmed/21621269 Genome-wide association analysis of gender differences in major depressive disorder in the Netherlands NESDA and NTR population-based samples. Major depressive disorder 1,726 cases, 1,630 controls NA Perlegen [433556] 5 unipolar depression http://www.ebi.ac.uk/efo/EFO_0003761 GCST001083 Genome-wide genotyping array 3356 2012-11-04 22951595 Hwang JY 2012-09-06 J Hum Genet www.ncbi.nlm.nih.gov/pubmed/22951595 Genome-wide association study identifies GYS2 as a novel genetic factor for polycystic ovary syndrome through obesity-related condition. Polycystic ovary syndrome 774 Korean ancestry cases, 967 Korean ancestry controls 482 Korean ancestry children, 468 Korean ancestry pregnant female individuals, 1,242 Korean ancestry female controls Illumina [~ 3091653] (imputed) 0 polycystic ovary syndrome http://www.ebi.ac.uk/efo/EFO_0000660 GCST001669 Genome-wide genotyping array 1741 2013-02-08 23180272 Park BL 2012-11-21 Hum Genet www.ncbi.nlm.nih.gov/pubmed/23180272 Genome-wide association study of aspirin-exacerbated respiratory disease in a Korean population. Aspirin exacerbated respiratory disease in asthmatics 117 Korean ancestry cases, 685 Korean ancestry controls 142 Korean ancestry cases, 996 Korean ancestry controls Illumina [430486] 1 Aspirin-induced asthma http://purl.obolibrary.org/obo/HP_0012042 GCST001747 Genome-wide genotyping array 802 2014-03-13 23918589 Negi S 2013-12-01 Arthritis Rheum www.ncbi.nlm.nih.gov/pubmed/23918589 A genome-wide association study reveals ARL15, a novel non-HLA susceptibility gene for rheumatoid arthritis in North Indians. Rheumatoid arthritis 706 North Indian ancestry cases, 761 North Indian ancestry controls 927 North Indian ancestry cases, 1,148 North Indian ancestry controls Illumina [559348] 2 rheumatoid arthritis http://www.ebi.ac.uk/efo/EFO_0000685 GCST002300 Genome-wide genotyping array 1467 2013-11-03 20350937 Takahashi M 2010-03-29 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/20350937 The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl. Thyroid cancer (Papillary, radiation-related) 401 European ancestry cases, 620 European ancestry controls 259 cases, 648 controls Illumina [506840] 1 thyroid carcinoma http://www.ebi.ac.uk/efo/EFO_0002892 GCST000640 Genome-wide genotyping array 1021 2012-06-18 22570617 Wiggs JL 2012-04-26 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22570617 Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma. Glaucoma (primary open-angle) 3,146 European ancestry cases, 3,487 European ancestry controls NA Illumina [495132] (imputed) 4 open-angle glaucoma http://www.ebi.ac.uk/efo/EFO_0004190 GCST001493 Genome-wide genotyping array 6633 2012-07-11 22532574 Stevens KN 2012-04-24 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/22532574 Identification of a novel percent mammographic density locus at 12q24. Percent mammographic density 1,241 European ancestry female individuals 9,126 European ancestry individuals Illumina [2510880] 1 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST001489 Genome-wide genotyping array 1241 2012-06-27 22570627 van Koolwijk LM 2012-05-03 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22570627 Common genetic determinants of intraocular pressure and primary open-angle glaucoma. Intraocular pressure 11,972 European ancestry individuals 7,482 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 2 intraocular pressure measurement http://www.ebi.ac.uk/efo/EFO_0004695 GCST001506 Genome-wide genotyping array 11972 2012-07-11 22584459 Sasayama D 2012-05-15 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/22584459 Possible association of CUX1 gene polymorphisms with antidepressant response in major depressive disorder. Response to antidepressants 92 Japanese ancestry cases 136 Japanese ancestry cases Illumina [291512] 1 response to antidepressant http://purl.obolibrary.org/obo/GO_0036276 GCST001528 Genome-wide genotyping array 92 2014-02-08 23871474 Psychosis Endophenotypes International Consortium 2013-07-17 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/23871474 A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation. Psychosis 1,239 European ancestry cases, 3,596 European ancestry control 10,352 cases, 24,474 controls Affymetrix [695193] 0 mental or behavioural disorder http://www.ebi.ac.uk/efo/EFO_0000677 GCST002096 Genome-wide genotyping array 4835 2013-05-30 23533358 Liu Z 2013-02-28 ScientificWorldJournal www.ncbi.nlm.nih.gov/pubmed/23533358 NCK2 is significantly associated with opiates addiction in African-origin men. Addiction 1,393 European ancestry females, 1,131 European ancestry males, 568 African ancestry females, 535 African ancestry males NA Illumina [859185] 3 drug dependence http://www.ebi.ac.uk/efo/EFO_0003890 GCST001880 Genome-wide genotyping array 3627 2013-09-16 23535732 Eeles RA 2013-04-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/23535732 Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Prostate cancer 11,085 European ancestry cases, 11,463 European ancestry controls 19,662 European ancestry cases, 19,715 European ancestry controls Illumina [~ 2600000] (imputed) 23 prostate carcinoma http://www.ebi.ac.uk/efo/EFO_0001663 GCST001942 Genome-wide genotyping array 22548 2015-04-22 23754948 Randall JC 2013-06-06 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/23754948 Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. Sexual dimorphism in anthropometric traits up to 60,586 European ancestry males, up to 73,137 European ancestry females up to 62,395 European ancestry males, up to 74,657 European ancestry females Affymetrix, Illumina [2846694] (imputed) 10 sexual dimorphism http://www.ebi.ac.uk/efo/EFO_0005951 GCST002063 Genome-wide genotyping array 133723 2010-08-11 20610541 Lascorz J 2010-07-07 Carcinogenesis www.ncbi.nlm.nih.gov/pubmed/20610541 Genome-wide association study for colorectal cancer identifies risk polymorphisms in German familial cases and implicates MAPK signalling pathways in disease susceptibility. Colorectal cancer 371 European ancestry cases, 1,263 European ancestry controls 4,915 European ancestry cases, 8,159 European ancestry controls Affymetrix [610664] 0 colorectal cancer http://www.ebi.ac.uk/efo/EFO_0005842 GCST000722 Genome-wide genotyping array 1634 2013-09-16 23633212 Rinella ES 2013-04-30 J Clin Endocrinol Metab www.ncbi.nlm.nih.gov/pubmed/23633212 Genome-wide association of single-nucleotide polymorphisms with weight loss outcomes after Roux-en-Y gastric bypass surgery. Weight loss (gastric bypass surgery) 86 European ancestry individuals with least EBWL, 89 European ancestry individuals with most EBWL 164 European ancestry individuals with least EBWL, 169 European ancestry individuals with most EBWL Affymetrix [730767] 2 body weight loss http://www.ebi.ac.uk/efo/EFO_0005245 GCST001985 Genome-wide genotyping array 175 2011-09-21 21841780 Chu X 2011-08-14 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21841780 A genome-wide association study identifies two new risk loci for Graves' disease. Graves' disease 1,468 Chinese ancestry cases, 1,490 Chinese ancestry controls 3,994 Chinese ancestry cases, 3,510 Chinese ancestry controls Illumina [486049] 11 Graves disease http://www.ebi.ac.uk/efo/EFO_0004237 GCST001200 Genome-wide genotyping array 2958 2011-08-05 21750111 Mbarek H 2011-07-12 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21750111 A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population. Hepatitis B 458 Japanese ancestry cases, 2,056 Japanese ancestry controls 2,209 Japanese ancestry cases, 4,440 Japanese ancestry controls Illumina [423627] 4 hepatitis B virus infection http://www.ebi.ac.uk/efo/EFO_0004197 GCST001150 Genome-wide genotyping array 2514 2011-11-30 22012869 Hinney A 2011-10-19 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/22012869 Genome-wide association study in German patients with attention deficit/hyperactivity disorder. Attention deficit hyperactivity disorder 495 European ancestry child and adolescent cases, 1,300 European ancestry adult controls 1,023 European ancestry individuals from 320 families, 2455 European ancestry cases and 896 European ancestry controls from 2,064 trios Illumina [487484] 2 attention deficit hyperactivity disorder http://www.ebi.ac.uk/efo/EFO_0003888 GCST001287 Genome-wide genotyping array 1795 2011-10-16 21940522 Shaffer JR 2011-09-21 J Dent Res www.ncbi.nlm.nih.gov/pubmed/21940522 Genome-wide association scan for childhood caries implicates novel genes. Dental caries 1,305 European ancestry children 1,695 European ancestry children Illumina [1450678] (imputed) 3 dental caries http://www.ebi.ac.uk/efo/EFO_0003819 GCST001244 Genome-wide genotyping array 1305 2012-08-07 22693455 Perry JR 2012-05-31 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22693455 Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. Type 2 diabetes 2,112 lean type 2 diabetes cases, 4,123 obese type 2 diabetes cases, 54,412 controls 2,881 lean type 2 diabetes cases, 8,702 obese type 2 diabetes cases, 18,957 controls NR [NR] 12 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST001550 Genome-wide genotyping array 60651 2014-03-04 23934736 Yu B 2013-08-11 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/23934736 Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study. Metabolite levels (Dihydroxy docosatrienoic acid) 1,260 African American individuals NA Affymetrix [~ 2500000] (imputed) 20 dihydroxy docosatrienoic acid measurement http://www.ebi.ac.uk/efo/EFO_0005275 GCST002120 Genome-wide genotyping array 1260 2014-03-04 23934736 Yu B 2013-08-11 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/23934736 Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study. Metabolite levels (Pyroglutamine) 1,260 African American individuals NA Affymetrix [~ 2500000] (imputed) 23 pyroglutamine measurement http://www.ebi.ac.uk/efo/EFO_0005408 GCST002118 Genome-wide genotyping array 1260 2014-03-04 23934736 Yu B 2013-08-11 Genet Epidemiol www.ncbi.nlm.nih.gov/pubmed/23934736 Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study. Metabolite levels (X-11787) 1,260 African American individuals NA Affymetrix [~ 2500000] (imputed) 29 hydroxy-leucine measurement http://www.ebi.ac.uk/efo/EFO_0005276 GCST002119 Genome-wide genotyping array 1260 2013-08-07 23568457 Wade TD 2013-04-09 Int J Eat Disord www.ncbi.nlm.nih.gov/pubmed/23568457 Genetic variants associated with disordered eating. Anorexia nervosa 237 European ancestry female cases, 2,287 European ancestry female controls NA Illumina [6150213] (imputed) 15 eating disorder http://www.ebi.ac.uk/efo/EFO_0005203 GCST001961 Genome-wide genotyping array 2524 2013-08-07 23568457 Wade TD 2013-04-09 Int J Eat Disord www.ncbi.nlm.nih.gov/pubmed/23568457 Genetic variants associated with disordered eating. Bulimia nervosa 151 European ancestry female cases, 2,291 European ancestry female controls NA Illumina [6150213] (imputed) 23 bulimia nervosa http://www.ebi.ac.uk/efo/EFO_0005204 GCST001958 Genome-wide genotyping array 2442 2013-08-07 23568457 Wade TD 2013-04-09 Int J Eat Disord www.ncbi.nlm.nih.gov/pubmed/23568457 Genetic variants associated with disordered eating. Eating disorders (purging via substances) 600 European ancestry female cases, 1,921 European ancestry female controls NA Illumina [6150213] (imputed) 11 eating disorder http://www.ebi.ac.uk/efo/EFO_0005203 GCST001959 Genome-wide genotyping array 2521 2013-08-07 23568457 Wade TD 2013-04-09 Int J Eat Disord www.ncbi.nlm.nih.gov/pubmed/23568457 Genetic variants associated with disordered eating. Eating disorders 543 European ancestry female cases, 1,116 European ancestry female controls NA Illumina [6150213] (imputed) 8 eating disorder http://www.ebi.ac.uk/efo/EFO_0005203 GCST001960 Genome-wide genotyping array 1659 2012-03-20 22396660 Urabe Y 2012-03-01 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/22396660 A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1. Nephrolithiasis 904 Japanese ancestry cases, 7,471 Japanese ancestry controls 4,892 Japanese ancestry cases, 9,873 Japanese ancestry controls Illumina [556249] 3 nephrolithiasis http://www.ebi.ac.uk/efo/EFO_0004253 GCST001432 Genome-wide genotyping array 8375 2012-10-13 22863731 Cheung CL 2012-08-05 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22863731 Genome-wide association study identifies a susceptibility locus for thyrotoxic periodic paralysis at 17q24.3. Thyrotoxic hypokalemic periodic paralysis 69 Chinese ancestry cases, 1,170 East Asian ancestry controls 54 Chinese ancestry cases, 400 Taiwanese ancestry controls Illumina [486782] 1 Thyrotoxic periodic paralysis http://www.orpha.net/ORDO/Orphanet_79102 GCST001627 Genome-wide genotyping array 1239 2015-05-14 22005930 Hollingworth P 2011-10-18 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/22005930 Genome-wide association study of Alzheimer's disease with psychotic symptoms. Psychosis and Alzheimer's disease 1,039 European ancestry cases with psychosis, 5,659 European ancestry controls, 260 European, African American and Native American ancestry cases with psychosis from 264 families NA Illumina [1847262] (imputed) 11 Alzheimer's disease, psychotic symptoms http://www.ebi.ac.uk/efo/EFO_0000249, http://www.ebi.ac.uk/efo/EFO_0005940 GCST001285 Genome-wide genotyping array 7222 2015-05-14 22005930 Hollingworth P 2011-10-18 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/22005930 Genome-wide association study of Alzheimer's disease with psychotic symptoms. Psychosis in Alzheimer's disease 1,039 European ancestry cases with psychosis, 610 European ancestry cases without psychosis, 260 European, African American and Native American ancestry cases with psychosis and 125 European, African American and Native American ancestry cases without psychosis from 264 families NA Illumina [1882172] (imputed) 8 psychotic symptoms http://www.ebi.ac.uk/efo/EFO_0005940 GCST001282 Genome-wide genotyping array 2298 2012-05-11 22457343 Martinelli-Boneschi F 2012-03-28 Mult Scler www.ncbi.nlm.nih.gov/pubmed/22457343 A genome-wide association study in progressive multiple sclerosis. Multiple sclerosis 197 European ancestry cases, 234 European ancestry controls 379 European ancestry cases, 398 European ancestry controls Affymetrix [277866] 1 multiple sclerosis http://www.ebi.ac.uk/efo/EFO_0003885 GCST001459 Genome-wide genotyping array 431 2011-07-14 21703634 Wang KS 2011-06-22 J Psychiatr Res www.ncbi.nlm.nih.gov/pubmed/21703634 A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence. Alcohol dependence 1,283 European ancestry cases, 1,416 European ancestry controls 1,650 European ancestry cases and 1,684 European ancestry controls from 778 nuclear families Illumina [up to 818773] 2 alcohol dependence http://www.ebi.ac.uk/efo/EFO_0003829 GCST001121 Genome-wide genotyping array 2699 2013-04-24 21705454 Huang RS 2011-06-24 Clin Cancer Res www.ncbi.nlm.nih.gov/pubmed/21705454 Platinum sensitivity-related germline polymorphism discovered via a cell-based approach and analysis of its association with outcome in ovarian cancer patients. Response to platinum-based agents 87 European ancestry lymphoblastoid cell lines 52 European ancestry lymphoblastoid cell lines NR [2286186] 0 response to platinum based chemotherapy http://www.ebi.ac.uk/efo/EFO_0004647 GCST001127 Genome-wide genotyping array 87 2011-12-02 22051697 Du R 2011-11-01 J Allergy Clin Immunol www.ncbi.nlm.nih.gov/pubmed/22051697 Genome-wide association study reveals class I MHC-restricted T cell-associated molecule gene (CRTAM) variants interact with vitamin D levels to affect asthma exacerbations. Asthma 395 European ancestry child cases 584 Hispanic child cases Illumina [534290] 0 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST001309 Genome-wide genotyping array 395 2011-08-19 21795503 Alkelai A 2011-07-27 FASEB J www.ncbi.nlm.nih.gov/pubmed/21795503 Identification of new schizophrenia susceptibility loci in an ethnically homogeneous, family-based, Arab-Israeli sample. Schizophrenia 189 Arab-Israeli founder individuals from 57 families 627 European ancestry cases, 541 European ancestry controls Illumina [307472] 0 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST001176 Genome-wide genotyping array 246 2011-07-27 21738479 Reiner AP 2011-06-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21738479 Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). White blood cell count 16,388 African American individuals 3,551 Hispanic individuals, 14,767 Japanese ancestry individuals, 19,509 European ancestry individuals Affymetrix, Illumina [2489215] (imputed) 2 leukocyte count http://www.ebi.ac.uk/efo/EFO_0004308 GCST001133 Genome-wide genotyping array 16388 2012-09-29 22883433 Irish Schizophrenia Genomics Consortium and the Wellcome Trust Case Control Consortium 2 2012-08-07 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/22883433 Genome-wide association study implicates HLA-C*01:02 as a risk factor at the major histocompatibility complex locus in schizophrenia. Schizophrenia 1,606 European ancestry cases, 1,794 European ancestry controls 13,195 European ancestry cases, 31,021 European ancestry controls Affymetrix [6212339] 2 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST001631 Genome-wide genotyping array 3400 2011-05-27 21533024 Pare G 2011-04-21 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21533024 Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci. Soluble ICAM-1 22,435 European ancestry female individuals 9,813 individuals Illumina [334295] 3 ICAM-1 measurement http://www.ebi.ac.uk/efo/EFO_0004520 GCST001047 Genome-wide genotyping array 22435 2011-06-18 21665988 Horne BD 2011-06-10 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/21665988 Genome-wide significance and replication of the chromosome 12p11.22 locus near the PTHLH gene for peripartum cardiomyopathy. Peripartum cardiomyopathy 36 European ancestry female cases, 703 European ancestry female controls, 5 female cases 59 European ancestry female cases, 303 European ancestry female controls Illumina [541327] 0 peripartum cardiomyopathy http://www.ebi.ac.uk/efo/EFO_0002628 GCST001098 Genome-wide genotyping array 744 2012-09-14 22780124 Lind PA 2012-07-11 Addict Biol www.ncbi.nlm.nih.gov/pubmed/22780124 Genome-wide association study of a quantitative disordered gambling trait. Gambling 1,312 European ancestry twins from 894 families NA Illumina [2373249] (imputed) 5 gambling behaviour http://www.ebi.ac.uk/efo/EFO_0004699 GCST001601 Genome-wide genotyping array 2206 2014-04-04 23999434 Ho JE 2013-09-03 J Clin Invest www.ncbi.nlm.nih.gov/pubmed/23999434 Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling. Serum protein levels (sST2) 2,797 individuals NA Affymetrix [2500000] (imputed) 14 serum ST2 measurement http://www.ebi.ac.uk/efo/EFO_0005416 GCST002166 Genome-wide genotyping array 2797 2012-05-15 22488850 Zuo L 2012-04-04 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/22488850 Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence. Alcohol and nicotine co-dependence 818 European ancestry cases, 1,396 European ancestry controls, 449 African American cases, 480 African American controls NA Illumina [805814] 8 alcohol and nicotine codependence http://www.ebi.ac.uk/efo/EFO_0004776 GCST001471 Genome-wide genotyping array 3143 2012-08-16 22692763 Liu CT 2012-06-12 J Bone Miner Res www.ncbi.nlm.nih.gov/pubmed/22692763 Assessment of gene-by-sex interaction effect on bone mineral density. Bone mineral density (sex interaction) 16,297 European ancestry female individuals, 9,056 European ancestry male individuals 17,949 European, East Asian, and Hispanic ancestry female individuals, 6,814 European, East Asian, and Hispanic ancestry male individuals Illumina [> 2300000] (imputed) 0 sex interaction measurement, bone density http://www.ebi.ac.uk/efo/EFO_0008343, http://www.ebi.ac.uk/efo/EFO_0003923 GCST001566 Genome-wide genotyping array 25353 2012-08-10 22737229 Nishida N 2012-06-21 PLoS One www.ncbi.nlm.nih.gov/pubmed/22737229 Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean. Hepatitis B (viral clearance) 181 East Asian ancestry HBV carriers, 184 East Asian ancestry controls, 185 East Asian ancestry spontaneously HBV-resolved individuals Up to 8,045 East Asian ancestry HBV carriers, up to 9,003 East Asian ancestry controls, up to 3,995 East Asian ancestry spontaneously HBV-resolved individuals Affymetrix [597789] 4 hepatitis B virus infection http://www.ebi.ac.uk/efo/EFO_0004197 GCST001582 Genome-wide genotyping array 550 2012-05-25 22484627 Bradfield JP 2012-04-08 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22484627 A genome-wide association meta-analysis identifies new childhood obesity loci. Obesity 5,530 European ancestry cases, 8,318 European ancestry controls 2,214 European ancestry cases, 2,674 European ancestry controls Affymetrix, Illumina [2700000] (imputed) 5 obesity http://www.ebi.ac.uk/efo/EFO_0001073 GCST001475 Genome-wide genotyping array 13848 2015-05-08 22295569 Karunas AS 2011-11-01 Mol Biol (Mosk) www.ncbi.nlm.nih.gov/pubmed/22295569 [Genome-wide association study of bronchial asthma in the Volga-Ural region of Russia]. Asthma 141 Russian ancestry cases, 120 Tatar ancestry cases, 69 Bashkir ancestry cases, 145 Russian ancestry controls, 111 Tatar ancestry controls, 92 Bashkir ancestry controls 202 Russian, Tatar, and Bashkir ancestry cases, 109 Russian ancestry controls, 54 Tatar ancestry controls, 53 Bashkir ancestry controls Illumina [550915] 0 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST001306 Genome-wide genotyping array 678 2012-09-12 22763110 Zeggini E 2012-07-03 Lancet www.ncbi.nlm.nih.gov/pubmed/22763110 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. Osteoarthritis 7,410 European ancestry cases, 11,009 European ancestry controls 7,473 European ancestry cases, 42,938 European ancestry controls Illumina [485491] 4 osteoarthritis http://www.ebi.ac.uk/efo/EFO_0002506 GCST001592 Genome-wide genotyping array 18419 2011-03-02 21283782 Tore S 2011-01-20 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21283782 Application of a new method for GWAS in a related case/control sample with known pedigree structure: identification of new loci for nephrolithiasis. Nephrolithiasis 80 Sardinian cases, 94 Sardinian controls 125 European ancestry cases, 157 European ancestry controls Affymetrix [334674] 0 nephrolithiasis http://www.ebi.ac.uk/efo/EFO_0004253 GCST000951 Genome-wide genotyping array 174 2012-02-10 21931564 Nicholson G 2011-09-08 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21931564 A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection. Metabolite levels 142 European ancestry female twins 202 European ancestry individuals Illumina [2541644] (imputed) 3 metabolite measurement http://www.ebi.ac.uk/efo/EFO_0004725 GCST001220 Genome-wide genotyping array 142 2011-12-20 22126837 LeBlanc M 2011-11-28 J Psychiatr Res www.ncbi.nlm.nih.gov/pubmed/22126837 Genome-wide study identifies PTPRO and WDR72 and FOXQ1-SUMO1P1 interaction associated with neurocognitive function. Cognitive function 190 European ancestry schizophrenia cases, 157 European ancestry bipolar disorder cases, 353 European ancestry controls NA Affymetrix [550291] 2 mental process http://www.ebi.ac.uk/efo/EFO_0004323 GCST001332 Genome-wide genotyping array 700 2009-02-25 19125160 Feulner TM 2009-01-07 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/19125160 Examination of the current top candidate genes for AD in a genome-wide association study. Alzheimer's disease 491 European ancestry cases, 479 European ancestry controls NA Illumina [~ 550000] 1 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST000313 Genome-wide genotyping array 970 2010-09-01 20622881 Gretarsdottir S 2010-07-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20622881 Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm. Abdominal aortic aneurysm 1,292 European ancestry cases, 30,503 European ancestry controls 3,267 European ancestry cases, 7,451 European ancestry controls Illumina [293677] 2 Abdominal Aortic Aneurysm http://www.ebi.ac.uk/efo/EFO_0004214 GCST000727 Genome-wide genotyping array 31795 2011-06-08 21623375 Albagha OM 2011-05-29 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21623375 Genome-wide association identifies three new susceptibility loci for Paget's disease of bone. Paget's disease 741 European ancestry cases, 2,699 European ancestry controls 1,474 European ancestry cases, 1,671 European ancestry controls Illumina [2487078] (imputed) 9 osteitis deformans http://www.ebi.ac.uk/efo/EFO_0004261 GCST001086 Genome-wide genotyping array 3440 2013-06-26 23508266 Duan QL 2013-03-19 Pharmacogenomics J www.ncbi.nlm.nih.gov/pubmed/23508266 A genome-wide association study of bronchodilator response in asthmatics. Asthma (bronchodilator response) Up to 403 European ancestry asthmatic children and their parents 764 European ancestry cases, 592 Costa Rican ancestry cases Illumina [534290] 2 response to bronchodilator http://purl.obolibrary.org/obo/GO_0097366 GCST001911 Genome-wide genotyping array 403 2011-11-18 22004471 Frank J 2011-10-18 Addict Biol www.ncbi.nlm.nih.gov/pubmed/22004471 Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster. Alcohol dependence 1,333 European ancestry male cases, 2,168 European ancestry male controls NA Illumina [463044] 6 alcohol dependence http://www.ebi.ac.uk/efo/EFO_0003829 GCST001281 Genome-wide genotyping array 3501 2011-11-08 21989058 Qin Y 2011-10-18 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21989058 Association of 8q22.3 locus in Chinese Han with idiopathic premature ovarian failure (POF). Premature ovarian failure 391 Han Chinese ancestry cases, 895 Han Chinese ancestry controls 400 Han Chinese ancestry cases, 800 Han Chinese ancestry controls Affymetrix [642069] 1 primary ovarian insufficiency http://www.ebi.ac.uk/efo/EFO_0004266 GCST001284 Genome-wide genotyping array 1286 2011-08-20 21811574 van Manen D 2011-07-21 PLoS One www.ncbi.nlm.nih.gov/pubmed/21811574 Genome-wide association scan in HIV-1-infected individuals identifying variants influencing disease course. HIV-1 progression 404 cases NA Illumina [309494] 0 HIV-1 infection http://www.ebi.ac.uk/efo/EFO_0000180 GCST001171 Genome-wide genotyping array 404 2011-05-24 21460841 Naj AC 2011-04-03 Nat Genet www.ncbi.nlm.nih.gov/pubmed/21460841 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Alzheimer's disease (late onset) 8,309 European ancestry cases, 7,366 European ancestry controls 10,523 European ancestry cases, 28,231 European ancestry controls Affymetrix, Illumina [2324889] (imputed) 9 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST001026 Genome-wide genotyping array 15675 2013-11-14 23726511 Xie P 2013-05-28 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/23726511 Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder. Post-traumatic stress disorder 300 European ancestry cases, up to 1,538 European ancestry controls, 444 African American cases, up to 2,936 African American controls 207 European ancestry cases, up to 1,692 European ancestry controls, 89 African American cases, up to 655 African American controls Illumina [up to 871502] 2 post-traumatic stress disorder http://www.ebi.ac.uk/efo/EFO_0001358 GCST002038 Genome-wide genotyping array 5218 2013-11-14 23726511 Xie P 2013-05-28 Biol Psychiatry www.ncbi.nlm.nih.gov/pubmed/23726511 Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder. Post-traumatic stress disorder (asjusted for relatedness) up to 308 European ancestry cases, up to 1,538 European ancestry controls, up to 456 African American cases, up to 2,936 African American controls NA Illumina [up to 871502] 19 post-traumatic stress disorder http://www.ebi.ac.uk/efo/EFO_0001358 GCST002037 Genome-wide genotyping array 5238 2013-04-17 23297363 Cordell HJ 2013-01-07 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23297363 Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot. Tetralogy of Fallot 835 European ancestry cases, 5,159 European ancestry controls 798 European ancestry cases, 2,931 European ancestry controls Illumina [516131] 6 Tetralogy of Fallot http://purl.obolibrary.org/obo/HP_0001636 GCST001807 Genome-wide genotyping array 5994 2014-02-04 23874384 Viding E 2013-07-09 PLoS One www.ncbi.nlm.nih.gov/pubmed/23874384 Genetics of callous-unemotional behavior in children. Callous-unemotional behaviour 2,930 European ancestry children NA Affymetrix [1724317] (imputed) 3 callous-unemotional behaviour http://www.ebi.ac.uk/efo/EFO_0005322 GCST002092 Genome-wide genotyping array 2930 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Mean arterial pressure 360,863 European ancestry individuals, 145,502 East Asian ancestry individuals NA Affymetrix, Illumina [20537389] (imputed) 241 mean arterial pressure http://www.ebi.ac.uk/efo/EFO_0006340 GCST90018963 Genome-wide genotyping array 506365 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Mean corpuscular hemoglobin 350,472 European ancestry individuals, 128,028 East Asian ancestry individuals NA Affymetrix, Illumina [20535878] (imputed) 381 mean corpuscular hemoglobin http://www.ebi.ac.uk/efo/EFO_0004527 GCST90018964 Genome-wide genotyping array 478500 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Mean corpuscular hemoglobin concentration 350,468 European ancestry individuals, 135,482 East Asian ancestry individuals NA Affymetrix, Illumina [20536605] (imputed) 125 mean corpuscular hemoglobin concentration http://www.ebi.ac.uk/efo/EFO_0004528 GCST90018965 Genome-wide genotyping array 485950 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Mean corpuscular volume 350,473 European ancestry individuals, 129,832 East Asian ancestry individuals NA Affymetrix, Illumina [20535844] (imputed) 425 mean corpuscular volume http://www.ebi.ac.uk/efo/EFO_0004526 GCST90018966 Genome-wide genotyping array 480305 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Monocyte count 349,856 European ancestry individuals, 95,119 East Asian ancestry individuals NA Affymetrix, Illumina [20531031] (imputed) 355 monocyte count http://www.ebi.ac.uk/efo/EFO_0005091 GCST90018967 Genome-wide genotyping array 444975 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Neutrophil count 349,856 European ancestry individuals, 82,810 East Asian ancestry individuals NA Affymetrix, Illumina [20526770] (imputed) 343 neutrophil count http://www.ebi.ac.uk/efo/EFO_0004833 GCST90018968 Genome-wide genotyping array 432666 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Platelet count 350,474 European ancestry individuals, 148,623 East Asian ancestry individuals NA Affymetrix, Illumina [20538505] (imputed) 516 platelet count http://www.ebi.ac.uk/efo/EFO_0004309 GCST90018969 Genome-wide genotyping array 499097 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Pulse pressure 360,863 European ancestry individuals, 145,445 East Asian ancestry individuals NA Affymetrix, Illumina [20537391] (imputed) 333 pulse pressure measurement http://www.ebi.ac.uk/efo/EFO_0005763 GCST90018970 Genome-wide genotyping array 506308 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Red blood cell count 350,475 European ancestry individuals, 153,512 East Asian ancestry individuals NA Affymetrix, Illumina [20538708] (imputed) 425 erythrocyte count http://www.ebi.ac.uk/efo/EFO_0004305 GCST90018971 Genome-wide genotyping array 503987 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Systolic blood pressure 340,159 European ancestry individuals, 145,505 East Asian ancestry individuals NA Affymetrix, Illumina [20537302] (imputed) 300 systolic blood pressure http://www.ebi.ac.uk/efo/EFO_0006335 GCST90018972 Genome-wide genotyping array 485664 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Total bilirubin levels 342,829 European ancestry individuals, 124,341 East Asian ancestry individuals NA Affymetrix, Illumina [20535842] (imputed) 145 bilirubin measurement http://www.ebi.ac.uk/efo/EFO_0004570 GCST90018973 Genome-wide genotyping array 467170 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Total cholesterol levels 344,278 European ancestry individuals, 135,808 East Asian ancestry individuals NA Affymetrix, Illumina [20536134] (imputed) 183 total cholesterol measurement http://www.ebi.ac.uk/efo/EFO_0004574 GCST90018974 Genome-wide genotyping array 480086 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Triglycerides 343,992 European ancestry individuals, 111,667 East Asian ancestry individuals NA Affymetrix, Illumina [20531459] (imputed) 258 triglyceride measurement http://www.ebi.ac.uk/efo/EFO_0004530 GCST90018975 Genome-wide genotyping array 455659 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Serum total protein level 314,921 European ancestry individuals, 133,321 East Asian ancestry individuals NA Affymetrix, Illumina [20536782] (imputed) 297 total blood protein measurement http://www.ebi.ac.uk/efo/EFO_0004536 GCST90018976 Genome-wide genotyping array 448242 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Serum uric acid levels 343,836 European ancestry individuals, 129,405 East Asian ancestry individuals NA Affymetrix, Illumina [20535231] (imputed) 279 uric acid measurement http://www.ebi.ac.uk/efo/EFO_0004761 GCST90018977 Genome-wide genotyping array 473241 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. White blood cell count 350,470 European ancestry individuals, 154,355 East Asian ancestry individuals NA Affymetrix, Illumina [20538670] (imputed) 420 leukocyte count http://www.ebi.ac.uk/efo/EFO_0004308 GCST90018978 Genome-wide genotyping array 504825 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Serum creatinine levels 344,104 European ancestry individuals, 150,266 East Asian ancestry individuals NA Affymetrix, Illumina [20538295] (imputed) 427 creatinine measurement http://www.ebi.ac.uk/efo/EFO_0004518 GCST90018979 Genome-wide genotyping array 494370 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (drugs for peptic ulcer and gastro-oesophageal reflux disease) 53,137 European ancestry cases, 79,230 European ancestry controls, 53,363 East Asian ancestry cases, 125,363 East Asian ancestry controls NA Affymetrix, Illumina [15248280] (imputed) 6 Peptic ulcer and gastro-oesophageal reflux disease (GORD) drug use measurement http://www.ebi.ac.uk/efo/EFO_0009923 GCST90018980 Genome-wide genotyping array 311093 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (drugs used in diabetes) 15,272 European ancestry cases, 290,641 European ancestry controls, 30,515 East Asian ancestry cases, 148,211 East Asian ancestry controls NA Affymetrix, Illumina [15248280] (imputed) 122 Drugs used in diabetes use measurement http://www.ebi.ac.uk/efo/EFO_0009924 GCST90018981 Genome-wide genotyping array 484639 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (antithrombotic agents) 67,653 European ancestry cases, 85,986 European ancestry controls, 54,220 East Asian ancestry cases, 124,506 East Asian ancestry controls NA Affymetrix, Illumina [15248280] (imputed) 35 Antithrombotic agent use measurement http://www.ebi.ac.uk/efo/EFO_0009925 GCST90018982 Genome-wide genotyping array 332365 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (vasodilators used in cardiac diseases) 5,546 European ancestry cases, 237,113 European ancestry controls, 17,050 East Asian ancestry cases, 161,676 East Asian ancestry controls NA Affymetrix, Illumina [15248280] (imputed) 24 Vasodilators used in cardiac diseases use measurement http://www.ebi.ac.uk/efo/EFO_0009926 GCST90018983 Genome-wide genotyping array 421385 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (diuretics) 34,453 European ancestry cases, 194,633 European ancestry controls, 22,356 East Asian ancestry cases, 156,370 East Asian ancestry controls NA Affymetrix, Illumina [15248280] (imputed) 87 Diuretic use measurement http://www.ebi.ac.uk/efo/EFO_0009928 GCST90018985 Genome-wide genotyping array 407812 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (beta blocking agents) 31,700 European ancestry cases, 192,324 European ancestry controls, 20,367 East Asian ancestry cases, 158,359 East Asian ancestry controls NA Affymetrix, Illumina [15248280] (imputed) 72 Beta blocking agent use measurement http://www.ebi.ac.uk/efo/EFO_0009929 GCST90018986 Genome-wide genotyping array 402750 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (antihypertensives) 6,431 European ancestry cases, 145,949 European ancestry controls, 5,688 East Asian ancestry cases, 173,038 East Asian ancestry controls NA Affymetrix, Illumina [15248280] (imputed) 8 Antihypertensive use measurement http://www.ebi.ac.uk/efo/EFO_0009927 GCST90018984 Genome-wide genotyping array 331106 2021-10-20 34594039 Sakaue S 2021-09-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/34594039 A cross-population atlas of genetic associations for 220 human phenotypes. Medication use (calcium channel blockers) 31,904 European ancestry cases, 172,474 European ancestry controls, 49,327 East Asian ancestry cases, 129,399 East Asian ancestry controls NA Affymetrix, Illumina [15248280] (imputed) 113 Calcium channel blocker use measurement http://www.ebi.ac.uk/efo/EFO_0009930 GCST90018987 Genome-wide genotyping array 383104 2014-05-13 24204828 Zheng JS 2013-10-28 PLoS One www.ncbi.nlm.nih.gov/pubmed/24204828 Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits. Homeostasis model assessment of beta-cell function (dietary factor interaction) 820 European ancestry individuals NA Affymetrix [590000] 12 diet measurement, HOMA-B http://www.ebi.ac.uk/efo/EFO_0008111, http://www.ebi.ac.uk/efo/EFO_0004469 GCST002251 Genome-wide genotyping array 820 2014-05-13 24204828 Zheng JS 2013-10-28 PLoS One www.ncbi.nlm.nih.gov/pubmed/24204828 Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits. Fasting insulin (dietary factor interaction) 820 European ancestry individuals NA Affymetrix [590000] 14 diet measurement, fasting blood insulin measurement http://www.ebi.ac.uk/efo/EFO_0008111, http://www.ebi.ac.uk/efo/EFO_0004466 GCST002248 Genome-wide genotyping array 820 2014-05-13 24204828 Zheng JS 2013-10-28 PLoS One www.ncbi.nlm.nih.gov/pubmed/24204828 Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits. Homeostasis model assessment of insulin resistance (dietary factor interaction) 820 European ancestry individuals NA Affymetrix [590000] 15 diet measurement, HOMA-IR http://www.ebi.ac.uk/efo/EFO_0008111, http://www.ebi.ac.uk/efo/EFO_0004501 GCST002253 Genome-wide genotyping array 820 2011-10-06 21935397 Paternoster L 2011-09-15 PLoS One www.ncbi.nlm.nih.gov/pubmed/21935397 Genome-wide population-based association study of extremely overweight young adults--the GOYA study. Obesity (extreme) 2,633 European ancestry extremely obese adult cases, 2,740 European ancestry controls 29,181 European ancestry individuals Illumina [545349] 4 obesity http://www.ebi.ac.uk/efo/EFO_0001073 GCST001240 Genome-wide genotyping array 5373 2013-11-09 20018918 Solovieff N 2009-12-16 Blood www.ncbi.nlm.nih.gov/pubmed/20018918 Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster. Fetal hemoglobin levels 848 Black cases 305 Black cases, 406 Chinese ancestry cases, 113 Thai ancestry cases Illumina [~ 600000] 3 fetal hemoglobin measurement http://www.ebi.ac.uk/efo/EFO_0004576 GCST000545 Genome-wide genotyping array 848 2014-03-26 24124408 Hong KW 2013-09-30 Genomics Inform www.ncbi.nlm.nih.gov/pubmed/24124408 Genome-wide association study of orthostatic hypotension and supine-standing blood pressure changes in two korean populations. Orthostatic hypotension 667 Korean ancestry cases, 5,761 Korean ancestry controls NA Affymetrix [333651] 5 orthostatic hypotension http://www.ebi.ac.uk/efo/EFO_0005252 GCST002209 Genome-wide genotyping array 6428 2011-07-14 21701565 Malhotra A 2011-06-23 Obesity (Silver Spring) www.ncbi.nlm.nih.gov/pubmed/21701565 A genome-wide association study of BMI in American Indians. Body mass index 1,120 Pima Indian ancestry individuals 2,133 Pima Indian ancestry individuals Affymetrix [454194] 0 body mass index http://www.ebi.ac.uk/efo/EFO_0004340 GCST001123 Genome-wide genotyping array 1120 2009-09-28 17903299 Kathiresan S 2007-09-19 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/17903299 A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. Lipid traits 1,087 European ancestry individuals ~8,100 European ancestry individuals Affymetrix [70897] 0 lipid measurement http://www.ebi.ac.uk/efo/EFO_0004529 GCST000078 Genome-wide genotyping array 1087 2011-10-26 21980299 Bradfield JP 2011-09-29 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21980299 A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci. Type 1 diabetes 9,934 European ancestry cases, 16,956 European ancestry controls 1,120 European ancestry affected trios Affymetrix, Illumina [~ 2540000] (imputed) 9 type I diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001359 GCST001255 Genome-wide genotyping array 26890 2011-09-23 21871595 Day-Williams AG 2011-08-25 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/21871595 A variant in MCF2L is associated with osteoarthritis. Osteoarthritis 3,177 European ancestry cases, 4,894 European ancestry controls 15,864 European ancestry cases, 19,610 European ancestry controls NR [7258070] (imputed) 1 osteoarthritis http://www.ebi.ac.uk/efo/EFO_0002506 GCST001209 Genome-wide genotyping array 8071 2011-10-22 21980494 Germain M 2011-09-27 PLoS One www.ncbi.nlm.nih.gov/pubmed/21980494 Genetics of venous thrombosis: insights from a new genome wide association study. Venous thromboembolism 1,542 European ancestry cases, 1,110 European ancestry controls NA Illumina [481002] 4 venous thromboembolism http://www.ebi.ac.uk/efo/EFO_0004286 GCST001253 Genome-wide genotyping array 2652 2012-02-10 22239941 Png E 2012-01-13 BMC Med Genet www.ncbi.nlm.nih.gov/pubmed/22239941 A genome wide association study of pulmonary tuberculosis susceptibility in Indonesians. Tuberculosis 108 Indonesian ancestry cases, 115 Indonesian ancestry controls 600 Indonesian ancestry cases, 540 Indonesian ancestry controls, 1,837 European ancestry cases, 1,779 European ancestry controls Affymetrix [95207] 0 Tuberculosis http://www.orpha.net/ORDO/Orphanet_3389 GCST001377 Genome-wide genotyping array 223 2010-06-14 20460622 Seshadri S 2010-05-12 JAMA www.ncbi.nlm.nih.gov/pubmed/20460622 Genome-wide analysis of genetic loci associated with Alzheimer disease. Alzheimer's disease 973 incident AD cases, 2,033 prevalent AD cases, 22,604 controls of European and Hispanic ancestry 6,505 European ancestry cases, 13,532 European ancestry controls Affymetrix, Illumina [~ 2500000] (imputed) 1 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST000682 Genome-wide genotyping array 25610 2010-05-05 20383145 Chambers JC 2010-04-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20383145 Genetic loci influencing kidney function and chronic kidney disease. Creatinine levels 23,812 European ancestry individuals 16,626 European ancestry individuals Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) 5 creatinine measurement http://www.ebi.ac.uk/efo/EFO_0004518 GCST000651 Genome-wide genotyping array 23812 2010-04-02 20305777 Nakajima M 2010-03-18 PLoS One www.ncbi.nlm.nih.gov/pubmed/20305777 New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study. Knee osteoarthritis 899 Japanese ancestry cases, 3,396 Japanese ancestry controls 167 Japanese ancestry cases, 347 Japanese ancestry controls, 813 European ancestry cases, 1,071 European ancestry controls, Illumina [459393] 1 osteoarthritis, knee http://www.ebi.ac.uk/efo/EFO_0004616 GCST000629 Genome-wide genotyping array 4295 2010-09-14 20691247 Verweij KJ 2010-08-04 Biol Psychol www.ncbi.nlm.nih.gov/pubmed/20691247 A genome-wide association study of Cloninger's temperament scales: implications for the evolutionary genetics of personality. Personality dimensions 5,117 European ancestry individuals from 2567 families NA Affymetrix, Illumina [1252387] (imputed) 7 personality trait http://www.ebi.ac.uk/efo/EFO_0004365 GCST000754 Genome-wide genotyping array 7684 2014-03-11 23945395 Hara K 2013-08-14 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23945395 Genome-wide association study identifies three novel loci for type 2 diabetes. Type 2 diabetes 5,976 Japanese ancestry cases, 20,829 Japanese ancestry controls 24,416 East Asian ancestry cases, 13,985 East Asian ancestry controls Illumina [6209637] (imputed) 16 type II diabetes mellitus http://www.ebi.ac.uk/efo/EFO_0001360 GCST002128 Genome-wide genotyping array 26805 2010-09-11 20676096 Zhang H 2010-08-01 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20676096 Genome-wide association study identifies 1p36.22 as a new susceptibility locus for hepatocellular carcinoma in chronic hepatitis B virus carriers. Hepatocellular carcinoma 348 Chinese ancestry cases, 359 Chinese ancestry controls 2,121 Chinese ancestry cases, 1,748 Chinese ancestry controls Affymetrix [294566] 1 hepatocellular carcinoma http://www.ebi.ac.uk/efo/EFO_0000182 GCST000752 Genome-wide genotyping array 707 2014-02-06 23829686 Ding L 2013-07-05 Hum Genomics www.ncbi.nlm.nih.gov/pubmed/23829686 Rank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations. Asthma (childhood onset) 429 European ancestry affected offspring trios 52 African American affected offspring trios, 46 Hispanic affected offspring trios Affymetrix [786195] 19 childhood onset asthma http://www.ebi.ac.uk/efo/EFO_0004591 GCST002088 Genome-wide genotyping array 429 2014-01-10 23827383 Cadby G 2013-07-01 Lung Cancer www.ncbi.nlm.nih.gov/pubmed/23827383 A genome-wide association study for malignant mesothelioma risk. Malignant mesothelioma 428 European ancestry cases, 2,047 European ancestry controls 392 European ancestry cases, 367 European ancestry controls Illumina [2508203] (imputed) 0 mesothelioma http://www.ebi.ac.uk/efo/EFO_0000588 GCST002085 Genome-wide genotyping array 2475 2014-03-20 23962720 Speed D 2013-08-19 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23962720 A genome-wide association study and biological pathway analysis of epilepsy prognosis in a prospective cohort of newly treated epilepsy. Epilepsy (remission after treatment) 889 European and unknown ancestry epilepsy cases NA Illumina [6923995] (imputed) 7 response to drug, epilepsy http://purl.obolibrary.org/obo/GO_0042493, http://www.ebi.ac.uk/efo/EFO_0000474 GCST002141 Genome-wide genotyping array 889 2013-12-10 23738518 Luciano M 2013-06-05 Genes Brain Behav www.ncbi.nlm.nih.gov/pubmed/23738518 A genome-wide association study for reading and language abilities in two population cohorts. Word reading 6,649 European ancestry children and adolescents NA Illumina [~ 2400000] (imputed) 15 word reading http://www.ebi.ac.uk/efo/EFO_0005300 GCST002060 Genome-wide genotyping array 6649 2013-12-10 23738518 Luciano M 2013-06-05 Genes Brain Behav www.ncbi.nlm.nih.gov/pubmed/23738518 A genome-wide association study for reading and language abilities in two population cohorts. Reading and spelling 6,649 European ancestry children and adolescents NA Illumina [~ 2400000] (imputed) 10 reading and spelling ability http://www.ebi.ac.uk/efo/EFO_0005301 GCST002062 Genome-wide genotyping array 6649 2013-12-10 23738518 Luciano M 2013-06-05 Genes Brain Behav www.ncbi.nlm.nih.gov/pubmed/23738518 A genome-wide association study for reading and language abilities in two population cohorts. Non-word repetition 6,649 European ancestry children and adolescents NA Illumina [~ 2400000] (imputed) 5 non-word reading http://www.ebi.ac.uk/efo/EFO_0005299 GCST002059 Genome-wide genotyping array 6649 2013-09-14 23620144 Sulkava S 2013-04-29 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23620144 Genome-wide scan of job-related exhaustion with three replication studies implicate a susceptibility variant at the UST gene locus. Job-related exhaustion 1,256 European ancestry individuals 13,864 European ancestry individuals Illumina [555388] 1 occupation-related stress disorder http://www.ebi.ac.uk/efo/EFO_0005250 GCST001983 Genome-wide genotyping array 1256 2010-09-01 20622880 Bezzina CR 2010-07-11 Nat Genet www.ncbi.nlm.nih.gov/pubmed/20622880 Genome-wide association study identifies a susceptibility locus at 21q21 for ventricular fibrillation in acute myocardial infarction. Ventricular fibrillation Up to 515 European ancestry cases, 457 European ancestry controls 146 European ancestry cases, 391 European ancestry controls Illumina [507436] 0 ventricular fibrillation http://www.ebi.ac.uk/efo/EFO_0004287 GCST000725 Genome-wide genotyping array 972 2013-06-06 23419831 Ramanan VK 2013-02-19 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/23419831 APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study. Alzheimer's disease biomarkers 555 European ancestry individuals NA Illumina [6108668] (imputed) 13 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST001868 Genome-wide genotyping array 555 2013-02-06 23184150 Henrion M 2012-11-25 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/23184150 Common variation at 2q22.3 (ZEB2) influences the risk of renal cancer. Renal cell carcinoma 2,215 European ancestry cases, 8,566 European ancestry controls 3,739 European ancestry cases, 8,786 European ancestry controls Illumina [284377] 2 renal cell carcinoma http://www.ebi.ac.uk/efo/EFO_0000681 GCST001750 Genome-wide genotyping array 10781 2015-06-12 25457201 de Tayrac M 2014-10-18 J Hepatol www.ncbi.nlm.nih.gov/pubmed/25457201 Genome-wide association study identifies TF as a significant modifier gene of iron metabolism in HFE hemochromatosis. Hereditary hemochromatosis-related traits (HFE mutation homozygotes) 474 European ancestry cases 746 European ancestry cases Illumina [534213] 2 hereditary hemochromatosis type 1, transferrin measurement, serum iron measurement http://www.ebi.ac.uk/efo/EFO_0006513, http://www.ebi.ac.uk/efo/EFO_0006341, http://www.ebi.ac.uk/efo/EFO_0006332 GCST002660 Genome-wide genotyping array 474 2015-05-16 25451450 Jacobsen KK 2014-10-12 J Affect Disord www.ncbi.nlm.nih.gov/pubmed/25451450 Genome wide association study identifies variants in NBEA associated with migraine in bipolar disorder. Migraine in bipolar disorder 460 European ancestry cases with migraine, 914 European ancestry cases without migraine 289 European ancestry cases with migraine, 697 European ancestry without migraine Affymetrix [723224] 0 migraine disorder http://www.ebi.ac.uk/efo/EFO_0003821 GCST002656 Genome-wide genotyping array 1374 2015-09-15 25387706 Vaidyanathan U 2014-12-01 Psychophysiology www.ncbi.nlm.nih.gov/pubmed/25387706 Heritability and molecular genetic basis of electrodermal activity: a genome-wide association study. Electrodermal activity Up to 4,424 European ancestry twins and their parents NA Illumina [527829] 13 skin conductance level, skin conductance response frequency, electrodermal activity measurement, skin conductance response amplitude http://www.ebi.ac.uk/efo/EFO_0006867, http://www.ebi.ac.uk/efo/EFO_0006869, http://www.ebi.ac.uk/efo/EFO_0006866, http://www.ebi.ac.uk/efo/EFO_0006868 GCST002706 Genome-wide genotyping array 4424 2014-10-30 24578125 Olden M 2014-02-27 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/24578125 Common variants in UMOD associate with urinary uromodulin levels: a meta-analysis. Urinary uromodulin levels 10,884 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 5 urinary uromodulin measurement http://www.ebi.ac.uk/efo/EFO_0005663 GCST002376 Genome-wide genotyping array 10884 2014-06-28 24277619 Quillen EE 2013-11-26 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/24277619 "ALDH2 is associated to alcohol dependence and is the major genetic determinant of ""daily maximum drinks"" in a GWAS study of an isolated rural Chinese sample." Alcohol dependence 102 Han Chinese ancestry cases, 212 Han Chinese ancestry controls NA Illumina [247725] 2 alcohol dependence http://www.ebi.ac.uk/efo/EFO_0003829 GCST002293 Genome-wide genotyping array 314 2014-06-28 24277619 Quillen EE 2013-11-26 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/24277619 "ALDH2 is associated to alcohol dependence and is the major genetic determinant of ""daily maximum drinks"" in a GWAS study of an isolated rural Chinese sample." Response to alcohol consumption (flushing response) 108 Han Chinese ancestry cases, 190 Han Chinese ancestry controls NA Illumina [247725] 3 response to alcohol http://www.ebi.ac.uk/efo/EFO_0005526 GCST002292 Genome-wide genotyping array 298 2014-06-28 24277619 Quillen EE 2013-11-26 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/24277619 "ALDH2 is associated to alcohol dependence and is the major genetic determinant of ""daily maximum drinks"" in a GWAS study of an isolated rural Chinese sample." Alcohol consumption (max-drinks) 272 Han Chinese ancestry individuals NA Illumina [247725] 3 alcohol drinking http://www.ebi.ac.uk/efo/EFO_0004329 GCST002294 Genome-wide genotyping array 272 2014-04-01 24047820 St Pourcain B 2013-09-18 Mol Autism www.ncbi.nlm.nih.gov/pubmed/24047820 Common variation contributes to the genetic architecture of social communication traits. Social communication problems 5,584 European ancestry children 1,364 European ancestry children Illumina [~ 2500000] (imputed) 4 social communication impairment http://www.ebi.ac.uk/efo/EFO_0005427 GCST002194 Genome-wide genotyping array 5584 2015-07-27 25500335 Tintle NL 2014-12-02 Prostaglandins Leukot Essent Fatty Acids www.ncbi.nlm.nih.gov/pubmed/25500335 A genome-wide association study of saturated, mono- and polyunsaturated red blood cell fatty acids in the Framingham Heart Offspring Study. Red blood cell fatty acid levels 2,633 individuals NA Affymetrix [~ 2500000] (imputed) 13 arachidonic acid measurement, fatty acid measurement, linolenic acid measurement, oleic acid measurement, docosapentaenoic acid measurement, linoleic acid measurement http://www.ebi.ac.uk/efo/EFO_0006808, http://www.ebi.ac.uk/efo/EFO_0005110, http://www.ebi.ac.uk/efo/EFO_0006811, http://www.ebi.ac.uk/efo/EFO_0006810, http://www.ebi.ac.uk/efo/EFO_0006809, http://www.ebi.ac.uk/efo/EFO_0006807 GCST002712 Genome-wide genotyping array 2633 2015-02-05 24943344 Ferrari R 2014-07-01 Lancet Neurol www.ncbi.nlm.nih.gov/pubmed/24943344 Frontotemporal dementia and its subtypes: a genome-wide association study. Frontotemporal dementia 1,377 European ancestry behavioural variant cases, 308 European ancestry Semantic dementia cases, 269 European ancestry Progressive nonfluent aphasia cases, 200 European ancestry Frontotremporal dementia with motor neuron disease cases, up to 4,308 European ancestry controls 690 European ancestry behavioural variant cases, 190 European ancestry Semantic dementia cases, 221 European ancestry Progressive nonfluent aphasia cases, 94 European ancestry Frontotremporal dementia with motor neuron disease cases, 177 European ancestry Frontotemporal lobar degeneration cases, up to 5,094 European ancestry controls Illumina [6026385] (imputed) 2 Frontotemporal dementia http://www.orpha.net/ORDO/Orphanet_282 GCST002516 Genome-wide genotyping array 6462 2015-07-09 25101718 Lee JH 2015-03-01 Am J Respir Cell Mol Biol www.ncbi.nlm.nih.gov/pubmed/25101718 IREB2 and GALC are associated with pulmonary artery enlargement in chronic obstructive pulmonary disease. Pulmonary artery enlargement and chronic obstructive pulmonary disease 1,006 European ancestry cases, 260 African American cases, 2,712 European ancestry smoker controls, 1,749 African American smoker controls NA Illumina [NR] (imputed) 1 pulmonary artery enlargement, chronic obstructive pulmonary disease http://www.ebi.ac.uk/efo/EFO_0006347, http://www.ebi.ac.uk/efo/EFO_0000341 GCST002798 Genome-wide genotyping array 5727 2015-07-09 25101718 Lee JH 2015-03-01 Am J Respir Cell Mol Biol www.ncbi.nlm.nih.gov/pubmed/25101718 IREB2 and GALC are associated with pulmonary artery enlargement in chronic obstructive pulmonary disease. Pulmonary artery enlargement in chronic obstructive pulmonary disease 1,006 European ancestry cases, 260 African American cases, 3,281 European ancestry controls, 494 African American controls NA Illumina [NR] (imputed) 2 pulmonary artery enlargement http://www.ebi.ac.uk/efo/EFO_0006347 GCST002797 Genome-wide genotyping array 5041 2015-07-09 25101718 Lee JH 2015-03-01 Am J Respir Cell Mol Biol www.ncbi.nlm.nih.gov/pubmed/25101718 IREB2 and GALC are associated with pulmonary artery enlargement in chronic obstructive pulmonary disease. Chronic obstructive pulmonary disease 3,281 European ancestry cases, 494 African American cases, 2,712 European ancestry smoker controls, 1,749 African American smoker controls NA Illumina [NR] (imputed) 5 chronic obstructive pulmonary disease http://www.ebi.ac.uk/efo/EFO_0000341 GCST002795 Genome-wide genotyping array 8236 2014-11-15 24823311 Guan W 2014-05-13 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/24823311 Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium. Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) 8,631 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 10 omega-6 polyunsaturated fatty acid measurement http://www.ebi.ac.uk/efo/EFO_0005680 GCST002450 Genome-wide genotyping array 8631 2014-11-15 24823311 Guan W 2014-05-13 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/24823311 Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium. Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) 8,631 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 8 omega-6 polyunsaturated fatty acid measurement http://www.ebi.ac.uk/efo/EFO_0005680 GCST002449 Genome-wide genotyping array 8631 2014-11-15 24823311 Guan W 2014-05-13 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/24823311 Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium. Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) 8,631 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 6 omega-6 polyunsaturated fatty acid measurement http://www.ebi.ac.uk/efo/EFO_0005680 GCST002448 Genome-wide genotyping array 8631 2014-11-15 24823311 Guan W 2014-05-13 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/24823311 Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium. Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) 8,631 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 8 omega-6 polyunsaturated fatty acid measurement http://www.ebi.ac.uk/efo/EFO_0005680 GCST002446 Genome-wide genotyping array 8631 2014-11-15 24823311 Guan W 2014-05-13 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/24823311 Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium. Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) 8,631 European ancestry individuals NA Affymetrix, Illumina [~ 2500000] (imputed) 8 omega-6 polyunsaturated fatty acid measurement http://www.ebi.ac.uk/efo/EFO_0005680 GCST002444 Genome-wide genotyping array 8631 2015-08-14 25533491 Rautanen A 2014-12-18 Lancet Respir Med www.ncbi.nlm.nih.gov/pubmed/25533491 Genome-wide association study of survival from sepsis due to pneumonia: an observational cohort study. Sepsis from pneumonia (survival) 359 European ancestry non-survivor cases, 1,194 European ancestry survivor cases 106 European ancestry non-survivor cases, 432 European ancestry survivor cases Affymetrix, Illumina [5888277] (imputed) 2 survival time, pneumonia, septic shock, Sepsis http://www.ebi.ac.uk/efo/EFO_0000714, http://www.ebi.ac.uk/efo/EFO_0003106, http://www.ebi.ac.uk/efo/EFO_0006834, http://purl.obolibrary.org/obo/HP_0100806 GCST002725 Genome-wide genotyping array 1553 2015-04-30 25173105 Gharahkhani P 2014-08-31 Nat Genet www.ncbi.nlm.nih.gov/pubmed/25173105 Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma. Glaucoma (primary open-angle) 1,155 European ancestry cases, 1,922 European ancestry controls 3,548 European ancestry cases, 9,496 European ancestry controls Illumina [7594768] (imputed) 9 open-angle glaucoma http://www.ebi.ac.uk/efo/EFO_0004190 GCST002582 Genome-wide genotyping array 3077 2015-07-09 25199915 Broer L 2014-09-08 J Gerontol A Biol Sci Med Sci www.ncbi.nlm.nih.gov/pubmed/25199915 GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy. Longevity (90 years and older) 6,036 European ancestry cases, 3,757 European ancestry controls NA Affymetrix, Illumina [2500000] (imputed) 7 longevity http://www.ebi.ac.uk/efo/EFO_0004300 GCST002599 Genome-wide genotyping array 9793 2012-06-19 22446962 Onouchi Y 2012-03-25 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22446962 A genome-wide association study identifies three new risk loci for Kawasaki disease. Kawasaki disease 428 Japanese ancestry cases, 3,379 Japanese ancestry controls 754 Japanese ancestry cases, 947 Japanese ancestry controls Illumina [463793] 5 mucocutaneous lymph node syndrome http://www.ebi.ac.uk/efo/EFO_0004246 GCST001455 Genome-wide genotyping array 3807 2012-03-20 22388998 Zhang CK 2012-01-19 Am J Hematol www.ncbi.nlm.nih.gov/pubmed/22388998 Genome-wide association study of N370S homozygous Gaucher disease reveals the candidacy of CLN8 gene as a genetic modifier contributing to extreme phenotypic variation. Gaucher disease severity 139 Ashkenazi Jewish cases NA Illumina [540902] 3 Gaucher disease http://www.orpha.net/ORDO/Orphanet_355 GCST001380 Genome-wide genotyping array 139 2011-09-30 21908515 Cai Q 2011-09-09 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21908515 Genome-wide association study identifies breast cancer risk variant at 10q21.2: results from the Asia Breast Cancer Consortium. Breast cancer 2,062 East Asian ancestry cases, 2,066 East Asian ancestry controls 15,091 East Asian ancestry cases, 14,877 East Asian ancestry controls Affymetrix [684457] 2 breast carcinoma http://www.ebi.ac.uk/efo/EFO_0000305 GCST001224 Genome-wide genotyping array 4128 2011-09-27 21901158 Irvin MR 2011-08-25 PLoS One www.ncbi.nlm.nih.gov/pubmed/21901158 Genome-wide detection of allele specific copy number variation associated with insulin resistance in African Americans from the HyperGEN study. Insulin resistance/response 1,040 African American individuals NA Affymetrix [872243] 14 insulin resistance http://www.ebi.ac.uk/efo/EFO_0002614 GCST001208 Genome-wide genotyping array 1040 2011-09-02 21814517 Noguchi E 2011-07-21 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21814517 Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations. Asthma 938 Japanese ancestry cases, 2,376 Japanese ancestry controls 1653 East Asian ancestry cases, 1453 East Asian ancestry controls Illumina [450326] 2 asthma http://www.ebi.ac.uk/efo/EFO_0000270 GCST001172 Genome-wide genotyping array 3314 2011-08-06 21764829 Png E 2011-07-15 Hum Mol Genet www.ncbi.nlm.nih.gov/pubmed/21764829 A genome-wide association study of hepatitis B vaccine response in an Indonesian population reveals multiple independent risk variants in the HLA region. Hepatitis B vaccine response 1,683 Indonesian ancestry individuals 1,931 Indonesian ancestry individuals Illumina [455508] 3 response to vaccine http://www.ebi.ac.uk/efo/EFO_0004645 GCST001162 Genome-wide genotyping array 1683 2011-07-19 21738491 Arking DE 2011-06-30 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21738491 Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals. Sudden cardiac arrest 1,283 European ancestry cases, ~20,000 European ancestry controls 3,119 European ancestry cases, 11,146 European ancestry controls Affymetrix, Illumina [~ 2500000] (imputed) 1 sudden cardiac arrest http://www.ebi.ac.uk/efo/EFO_0004278 GCST001132 Genome-wide genotyping array 21283 2013-12-06 23761726 Yazar S 2013-06-06 Mol Vis www.ncbi.nlm.nih.gov/pubmed/23761726 Interrogation of the platelet-derived growth factor receptor alpha locus and corneal astigmatism in Australians of Northern European ancestry: results of a genome-wide association study. Corneal astigmatism 2,784 European ancestry individuals NA Illumina [~ 2500000] (imputed) 7 Astigmatism http://purl.obolibrary.org/obo/HP_0000483 GCST002064 Genome-wide genotyping array 2784 2011-11-04 21990027 Drago A 2011-10-11 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/21990027 The genetics of antipsychotic induced tremors: a genome-wide pathway analysis on the STEP-BD SCP sample. Response to antipsychotic therapy (extrapyramidal side effects) 409 European and other ancestry bipolar cases NA Affymetrix [NR] 1 response to antipsychotic drug http://purl.obolibrary.org/obo/GO_0097332 GCST001271 Genome-wide genotyping array 409 2011-08-12 21779181 Gorlova O 2011-07-14 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21779181 Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy. Systemic sclerosis 2,296 European ancestry cases, 5,172 European ancestry controls 3,175 European ancestry cases, 4,210 European ancestry controls Illumina [NR] (imputed) 6 systemic scleroderma http://www.ebi.ac.uk/efo/EFO_0000717 GCST001160 Genome-wide genotyping array 7468 2011-08-12 21779181 Gorlova O 2011-07-14 PLoS Genet www.ncbi.nlm.nih.gov/pubmed/21779181 Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy. Systemic sclerosis 2,296 European ancestry cases, 5,172 European ancestry controls 3,175 European ancestry cases, 4,210 European ancestry controls Illumina [NR] (imputed) 12 systemic scleroderma http://www.ebi.ac.uk/efo/EFO_0000717 GCST001156 Genome-wide genotyping array 7468 2010-06-02 20445134 Smith NL 2010-05-05 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/20445134 Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. Heart failure 20,926 European ancestry individuals, 2,895 African ancestry individuals NA Affymetrix, Illumina [2478304] (imputed) 16 heart failure http://www.ebi.ac.uk/efo/EFO_0003144 GCST000675 Genome-wide genotyping array 23821 2010-06-08 20452100 Kramer PL 2010-05-06 Neurobiol Aging www.ncbi.nlm.nih.gov/pubmed/20452100 Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study. Alzheimer's disease 185 European ancestry low NFT individuals, 114 European ancestry high NFT individuals NA Illumina [292175] 2 Alzheimer's disease http://www.ebi.ac.uk/efo/EFO_0000249 GCST000676 Genome-wide genotyping array 299 2010-04-02 20303062 Medland SE 2010-03-18 Am J Hum Genet www.ncbi.nlm.nih.gov/pubmed/20303062 A variant in LIN28B is associated with 2D:4D finger-length ratio, a putative retrospective biomarker of prenatal testosterone exposure. Digit length ratio 2,889 European ancestry children and adolescents 3,659 European ancestry children Illumina [310613] 1 digit length ratio http://www.ebi.ac.uk/efo/EFO_0004841 GCST000630 Genome-wide genotyping array 2889 2011-12-02 22037552 Yue WH 2011-10-30 Nat Genet www.ncbi.nlm.nih.gov/pubmed/22037552 Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2. Schizophrenia 746 Han Chinese ancestry cases, 1,599 Han Chinese ancestry controls 4,027 Han Chinese ancestry cases, 5,603 Han Chinese ancestry controls Illumina [493203] 2 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST001299 Genome-wide genotyping array 2345 2011-12-03 22068335 Mitchell GF 2011-11-08 Circ Cardiovasc Genet www.ncbi.nlm.nih.gov/pubmed/22068335 Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium. Aortic stiffness 4,216 Sardinian individuals, 20,634 European ancestry individuals 5,306 European ancestry individuals Affymetrix, Illumina [~ 2500000] (imputed) 1 carotid-femoral pulse wave velocity http://www.ebi.ac.uk/efo/EFO_0004724 GCST001317 Genome-wide genotyping array 24850 2012-09-26 22828495 Brown AA 2012-07-24 Transl Psychiatry www.ncbi.nlm.nih.gov/pubmed/22828495 Genetic variants affecting the neural processing of human facial expressions: evidence using a genome-wide functional imaging approach. Neural processing (facial expression) 246 European ancestry individuals 85 European ancestry individuals Affymetrix [549640] 0 facial neural processing http://www.ebi.ac.uk/efo/EFO_0004914 GCST001618 Genome-wide genotyping array 246 2015-04-28 22343285 Bakken TE 2012-02-16 Proc Natl Acad Sci U S A www.ncbi.nlm.nih.gov/pubmed/22343285 Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. Occipital cortical area (total cortical area interaction) 421 European ancestry individuals 760 European ancestry individuals Affymetrix [597198] 1 total cortical area measurement, visual cortical surface area measurement http://www.ebi.ac.uk/efo/EFO_0008381, http://www.ebi.ac.uk/efo/EFO_0004771 GCST001411 Genome-wide genotyping array 421 2015-05-13 21688384 Wang KS 2011-06-17 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/21688384 Genome-wide association analysis of age at onset in schizophrenia in a European-American sample. Schizophrenia (age at onset) 1,162 European ancestry cases 1,068 European ancestry cases Affymetrix [722112] 2 schizophrenia, age at onset http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0004847 GCST001115 Genome-wide genotyping array 1162 2015-05-13 21688384 Wang KS 2011-06-17 Am J Med Genet B Neuropsychiatr Genet www.ncbi.nlm.nih.gov/pubmed/21688384 Genome-wide association analysis of age at onset in schizophrenia in a European-American sample. Schizophrenia (age at onset) (sex interaction) 1,162 European ancestry cases 1,068 European ancestry cases Affymetrix [722112] 0 schizophrenia, age at onset http://www.ebi.ac.uk/efo/EFO_0000692, http://www.ebi.ac.uk/efo/EFO_0004847 GCST001114 Genome-wide genotyping array 1162 2011-07-08 21682944 Alkelai A 2011-06-20 Int J Neuropsychopharmacol www.ncbi.nlm.nih.gov/pubmed/21682944 DOCK4 and CEACAM21 as novel schizophrenia candidate genes in the Jewish population. Schizophrenia 155 Jewish-Israeli ancestry cases and 176 Jewish-Israeli ancestry controls from 107 families 99 Arab-Israeli ancestry cases and 99 Arab-Israeli ancestry controls from 57 families Illumina [311517] 2 schizophrenia http://www.ebi.ac.uk/efo/EFO_0000692 GCST001119 Genome-wide genotyping array 438 2013-09-27 23661040 Liao M 2013-05-10 Immunogenetics www.ncbi.nlm.nih.gov/pubmed/23661040 Genome-wide scan on total serum IgE levels identifies no common variants in a healthy Chinese male population. IgE levels 1,999 Han Chinese ancestry males 1,496 East Asian ancestry males Illumina [1940243] (imputed) 0 serum IgE measurement http://www.ebi.ac.uk/efo/EFO_0004579 GCST002019 Genome-wide genotyping array 1999 2014-03-15 23979607 Lubke GH 2013-08-27 Mol Psychiatry www.ncbi.nlm.nih.gov/pubmed/23979607 Genome-wide analyses of borderline personality features. Borderline personality disorder features up to 7,125 individuals 1,301 individuals Affymetrix, Illumina [6670475] 1 borderline personality disorder symptom http://www.ebi.ac.uk/efo/EFO_0005429 GCST002150 Genome-wide genotyping array 7125 2011-09-03 21771265 Yosifova A 2011-07-19 Genes Brain Behav www.ncbi.nlm.nih.gov/pubmed/21771265 Genome-wide association study on bipolar disorder in the Bulgarian population. Bipolar disorder 188 Bulgarian ancestry cases, 376 Bulgarian ancestry controls 122 Bulgarian ancestry cases, 328 Bulgarian ancestry controls Illumina [497732] 3 bipolar disorder http://www.ebi.ac.uk/efo/EFO_0000289 GCST001164 Genome-wide genotyping array 564 2010-08-12 20595679 Feehally J 2010-07-01 J Am Soc Nephrol www.ncbi.nlm.nih.gov/pubmed/20595679 HLA has strongest association with IgA nephropathy in genome-wide analysis. Nephropathy 187 European ancestry child cases, 244 European ancestry cases, 4,980 European ancestry controls NA Illumina [286200] 1 kidney disease http://www.ebi.ac.uk/efo/EFO_0003086 GCST000718 Genome-wide genotyping array 5411 2011-05-20 21467234 FitzGerald LM 2011-04-05 Cancer Epidemiol Biomarkers Prev www.ncbi.nlm.nih.gov/pubmed/21467234 Genome-wide association study identifies a genetic variant associated with risk for more aggressiv